| GO ID | Ontology | GO Term | Term Definition |
Proteins |
GO:0051873 | BP | killing by host of symbiont cells | Any process mediated by an organism that results in the death of cells in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. |
MBL2 |
GO:0051877 | BP | pigment granule aggregation in cell center | The directed movement of dispersed pigment granules towards the center of the cell. |
BBS7, MKKS |
GO:0051879 | MF | Hsp90 protein binding | Interacting selectively and non-covalently with Hsp90 proteins, any of a group of heat shock proteins around 90kDa in size. |
ARNTL, ERN1, GBP1, AHR, NUP62, NASP, PPID, KPNB1, CDC37, HIF1A, PACRG, NPAS2, HDAC8, HDAC6, CHORDC1, STUB1 |
GO:0051880 | MF | G-quadruplex DNA binding | Interacting selectively and non-covalently with G-quadruplex DNA structures, in which groups of four guanines adopt a flat, cyclic Hoogsteen hydrogen-bonding arrangement known as a guanine tetrad. The stacking of guanine tetrads results in G-quadruplex DNA structures. G-quadruplex DNA can form under physiological conditions from some G-rich sequences, such as those found in telomeres, immunoglobulin switch regions, gene promoters, fragile X repeats, and the dimerization domain in the human immunodeficiency virus (HIV) genome. |
BLM, RAD50, DHX36, PIF1 |
GO:0051881 | BP | regulation of mitochondrial membrane potential | Any process that modulates the establishment or extent of the mitochondrial membrane potential, the electric potential existing across the mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane. |
CLIC1, PARK2, TUSC2, BCL2, NDUFS1, UCP2, BAX, PID1, SPG20, SLC25A36, PINK1, PANK2, PRELID1 |
GO:0051882 | BP | mitochondrial depolarization | The process in which the potential difference across the mitochondrial membrane is reduced from its steady state level. |
CASP1 |
GO:0051891 | BP | positive regulation of cardioblast differentiation | Any process that activates or increases the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. |
GATA4, TGFB2, GATA6 |
GO:0051893 | BP | regulation of focal adhesion assembly | Any process that modulates the frequency, rate or extent of focal adhesion formation, the establishment and maturation of focal adhesions. |
RHOD, DAPK3, GREM1, ROCK2, EPHA3, EFNA5, PTK2, GPM6B, CORO1C, MACF1 |
GO:0051894 | BP | positive regulation of focal adhesion assembly | Any process that activates or increases the frequency, rate or extent of focal adhesion assembly, the establishment and maturation of focal adhesions. |
ITGB1BP1, VEGFA, SDC4, IQGAP1, LIMS1, PPM1F, S100A10, RAC1, SMAD3, TEK, COL16A1, PTPRJ, SFRP1 |
GO:0051895 | BP | negative regulation of focal adhesion assembly | Any process that stops, prevents, or reduces the frequency, rate or extent of focal adhesion assembly, the establishment and maturation of focal adhesions. |
ITGB1BP1, ARHGAP6, APOD, THBS1, MMP14, PTEN, PHLDB2, DLC1, CORO1C |
GO:0051896 | BP | regulation of protein kinase B signaling | Any process that modulates the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B. |
RRAS, SESN3, STK11, NTRK2, RICTOR |
GO:0051897 | BP | positive regulation of protein kinase B signaling | Any process that activates or increases the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B. |
HAX1, ITGB1BP1, TNFSF11, SPRY2, EGFR, TGFB1, INS, IGF2, TNF, PDGFA, IL6, INSR, GPX1, THBS1, CCL3, TXN, CD28, HCLS1, ZP3, IGFBP5, CHI3L1, TGFBR1, LEP, AKR1C3, PIK3CG, AKR1C2, ADAM8, NRG1, TEK, PTK2, C1QBP, PTPRJ, ILK, SEMA5A, IL18, GAS6, ANGPT1, ITSN1, FAM110C, RICTOR, MTDH, TSPYL5, GCNT2, MYDGF, RASD2, HBEGF, MEIS3, C1QTNF1, PINK1, OSBPL8, NOX4, TCF7L2, HPSE |
GO:0051898 | BP | negative regulation of protein kinase B signaling | Any process that stops, prevents, or reduces the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B. |
MSTN, KLF4, PDCD6, DRD2, DDIT3, XDH, TSC2, PTEN, RACK1, HYAL2, PTPRJ, DLG1, MTM1, RAPGEF1, DAG1, SFRP5, MAGI2, FLCN, PRKCDBP, GPER1, CIB1, INPP5K, LMBRD1 |
GO:0051899 | BP | membrane depolarization | The process in which membrane potential decreases with respect to its steady-state potential, usually from negative potential to a more positive potential. For example, the initial depolarization during the rising phase of an action potential is in the direction from the negative steady-state resting potential towards the positive membrane potential that will be the peak of the action potential. |
EDN1, JUN, CACNB3, CAV1, ADIPOQ, CACNA1E, P2RX4 |
GO:0051900 | BP | regulation of mitochondrial depolarization | Any process that modulates the frequency, rate or extent of the change in the membrane potential of the mitochondria from negative to positive. |
GCLC, GCLM |
GO:0051901 | BP | positive regulation of mitochondrial depolarization | Any process that activates, maintains or increases the frequency, rate or extent of the change in the membrane potential of the mitochondria from negative to positive. |
CCK, DCN, PARP1, TSPO, RACK1, MLLT11 |
GO:0051902 | BP | negative regulation of mitochondrial depolarization | Any process that stops, prevents, or reduces the frequency, rate or extent of the change in the membrane potential of the mitochondria from negative to positive. |
BCL2 |
GO:0051908 | MF | double-stranded DNA 5'-3' exodeoxyribonuclease activity | Catalysis of the sequential cleavage of mononucleotides from a free 5' terminus of a double-stranded DNA molecule. |
EXO1 |
GO:0051917 | BP | regulation of fibrinolysis | Any process that modulates the frequency, rate or extent of fibrinolysis, an ongoing process that solubilizes fibrin, resulting in the removal of small blood clots. |
APOH |
GO:0051918 | BP | negative regulation of fibrinolysis | Any process that stops, prevents, or reduces the frequency, rate or extent of fibrinolysis, an ongoing process that solubilizes fibrin, resulting in the removal of small blood clots. |
F2, PLG, APOH, SERPINE1, THBS1, CPB2 |
GO:0051919 | BP | positive regulation of fibrinolysis | Any process that activates, maintains or increases the frequency, rate or extent of fibrinolysis, an ongoing process that solubilizes fibrin, resulting in the removal of small blood clots. |
PLG |
GO:0051920 | MF | peroxiredoxin activity | Catalysis of the reaction: 2 R'-SH + ROOH = R'-S-S-R' + H2O + ROH. |
PRDX6, SESN1 |
GO:0051923 | BP | sulfation | The addition of a sulfate group to a molecule. |
SULT1A3, SULT2A1, CHSY1 |
GO:0051924 | BP | regulation of calcium ion transport | Any process that modulates the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
BEST1, AGT, GNAI2, BCL2, GJA1, PLN, SRI, CACNA2D1, ANK2 |
GO:0051926 | BP | negative regulation of calcium ion transport | Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
ICAM1, PLN, NOS3, PTGS2, STC1, LILRB1, INPP5K |
GO:0051928 | BP | positive regulation of calcium ion transport | Any process that activates or increases the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
CCL3, CCL4, CCL5, F2R, TSPO, ANK2, MYLK, HOMER1, P2RX4, WNK3, STIM2, TRPC6 |
GO:0051930 | BP | regulation of sensory perception of pain | Any process that modulates the frequency, rate or extent of the sensory perception of pain, the series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal. |
EDN1, CCK, CCL3, ACPP, COMT, F2R, ADORA1, NPY2R, GRIN2A, MGLL, PROL1, SPX |
GO:0051932 | BP | synaptic transmission, GABAergic | The process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA). |
RAC3, RAC1 |
GO:0051938 | BP | L-glutamate import | The directed movement of L-glutamate, the L-enantiomer of the anion of 2-aminopentanedioic acid, into a cell or organelle. |
SLC1A3, SLC1A2 |
GO:0051939 | BP | gamma-aminobutyric acid import | The directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate) into a cell or organelle. |
SLC6A1 |
GO:0051946 | BP | regulation of glutamate uptake involved in transmission of nerve impulse | Any process that modulates the frequency, rate or extent of the directed movement of L-glutamate into a neuron or glial cell. |
ATP1A2 |
GO:0051958 | BP | methotrexate transport | The directed movement of methotrexate, 4-amino-10-methylformic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Methotrexate is a folic acid analogue and a potent competitive inhibitor of dihydrofolate reductase. |
SLC19A1, SLC46A1 |
GO:0051959 | MF | dynein light intermediate chain binding | Interacting selectively and non-covalently with a light intermediate chain of the dynein complex. |
RAB11FIP3, DYNC1H1, BICD2 |
GO:0051963 | BP | regulation of synapse assembly | Any process that modulates the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse. |
MEF2C, NECTIN1, GHSR, PDLIM5 |
GO:0051964 | BP | negative regulation of synapse assembly | Any process that stops, prevents, or reduces the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse. |
WNT5A, PTK2, ROBO2 |
GO:0051965 | BP | positive regulation of synapse assembly | Any process that activates, maintains or increases the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse. |
FLRT2, SRPX2, CLSTN1, NTRK1, CBLN1, BDNF, EPHB2, OXTR, EFNA5, EPHB1, UBE2V2, ASIC2, NTRK2, LRRN1, LINGO2, SLITRK4, NLGN1, CLSTN2, ADGRL3, IL1RAP, FLRT3, FLRT1, GHRL, NRXN1 |
GO:0051966 | BP | regulation of synaptic transmission, glutamatergic | Any process that modulates the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate. |
GRM8, GRM6, DKK1, SERPINE2, CNR1, SYT1, PSEN1, ATP1A2, MEF2C, MAPK8IP2, GRM3 |
GO:0051967 | BP | negative regulation of synaptic transmission, glutamatergic | Any process that stops, prevents, or reduces the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate. |
DRD2, ADORA1, NPY2R, ATAD1 |
GO:0051968 | BP | positive regulation of synaptic transmission, glutamatergic | Any process that activates, maintains or increases the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate. |
EGFR, NTRK1, OXTR, PTGS2, NLGN1, TNR, NRXN1 |
GO:0051969 | BP | regulation of transmission of nerve impulse | Any process that modulates the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation. |
AGT |
GO:0051971 | BP | positive regulation of transmission of nerve impulse | Any process that activates, maintains or increases the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation. |
IL6, ITGA2, CARTPT, TNR |
GO:0051973 | BP | positive regulation of telomerase activity | Any process that activates or increases the frequency, rate or extent of telomerase activity, the catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). |
MAP2K7, KLF4, GREM1, DKC1, TNKS, TCP1, MAPK3, MAPK1, CTNNB1, NEK2, CCT2, PRKCQ, PARM1, NEK7, ACD, AURKB, OBFC1, POT1, MAP3K4 |
GO:0051974 | BP | negative regulation of telomerase activity | Any process that stops or reduces the activity of the enzyme telomerase, which catalyzes of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). |
TP53, PPARG, TERF1, PIF1, OBFC1, POT1 |
GO:0051977 | BP | lysophospholipid transport | The directed movement of phospholipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A lysophospholipid is a phospholipid that lacks one of its fatty acyl chains; it is an intermediate formed during digestion of dietary and biliary phospholipids. |
MFSD2A |
GO:0051978 | MF | lysophospholipid transporter activity | Enables the directed movement of lysophospholipids into, out of or within a cell, or between cells. A lysophospholipid is a phospholipid that lacks one of its fatty acyl chains; it is an intermediate formed during digestion of dietary and biliary phospholipids. |
MFSD2A |
GO:0051983 | BP | regulation of chromosome segregation | Any process that modulates the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets. |
ZNF207, BUB1, MKI67, PUM1, PUM2, AURKB, KIF2C |
GO:0051984 | BP | positive regulation of chromosome segregation | Any process that activates or increases the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets. |
SMC5, SMC6, CDC6, RAD18 |
GO:0051987 | BP | positive regulation of attachment of spindle microtubules to kinetochore | Any process that activates or increases the frequency, rate or extent of the attachment of spindle microtubules to the kinetochore. |
CCNB1, SIRT2 |
GO:0051988 | BP | regulation of attachment of spindle microtubules to kinetochore | Any process that modulates the frequency, rate or extent of the attachment of spindle microtubules to the kinetochore. |
APC, NEK2, CDC42, SPAG5, RACGAP1, ECT2, KNSTRN |
GO:0051990 | MF | (R)-2-hydroxyglutarate dehydrogenase activity | Catalysis of the reaction: (R)-2-hydroxyglutarate + acceptor = 2-oxoglutarate + reduced acceptor. |
IDH1 |
GO:0051996 | MF | squalene synthase activity | Catalysis of the reaction: presqualene diphosphate + NADPH = squalene + NADP+ + diphosphate. |
FDFT1 |
GO:0052066 | BP | entry of symbiont into host cell by promotion of host phagocytosis | The invasion by an organism of a cell of its host organism by utilizing the host phagocytosis mechanism. The host is defined as the larger of the organisms involved in a symbiotic interaction. |
ITGAV |
GO:0052106 | BP | quorum sensing involved in interaction with host | The process in which a community of single-celled organisms living in intimate contact with a host organism monitors population density by detecting the concentration of small diffusible signal molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction. |
SLC22A5 |
GO:0052314 | BP | phytoalexin metabolic process | The chemical reactions and pathways involving phytoalexins, any of a range of substances produced by plants as part of their defense response. |
TH |
GO:0052405 | BP | negative regulation by host of symbiont molecular function | Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the functional activity of symbiont proteins. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. |
RAB9A |
GO:0052547 | BP | regulation of peptidase activity | Any process that modulates the frequency, rate or extent of peptidase activity, the hydrolysis of peptide bonds within proteins. |
CAV1 |
GO:0052548 | BP | regulation of endopeptidase activity | Any process that modulates the frequency, rate or extent of endopeptidase activity, the endohydrolysis of peptide bonds within proteins. |
NRDC, FURIN, PSMA3, PSMB8, ATP13A2 |
GO:0052567 | BP | response to defense-related host reactive oxygen species production | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of reactive oxygen species produced as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. |
TUSC2 |
GO:0052591 | MF | sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity | Catalysis of the reaction: sn-glycerol 3-phosphate + ubiquinone-8 = glycerone phosphate + ubiquinol-8. |
GPD2 |
GO:0052593 | MF | tryptamine:oxygen oxidoreductase (deaminating) activity | Catalysis of the reaction: tryptamine + H2O + O2 = NH3 + indole acetaldehyde + hydrogen peroxide + H+. |
AOC2, AOC3 |
GO:0052594 | MF | aminoacetone:oxygen oxidoreductase(deaminating) activity | Catalysis of the reaction: aminoacetone + H2O + O2 = methylglyoxal + NH3 + hydrogen peroxide + H+. |
AOC2, AOC3 |
GO:0052595 | MF | aliphatic-amine oxidase activity | Catalysis of the reaction: an aliphatic amine + H2O + O2 = an aldehyde + NH3 + hydrogen peroxide + H+. |
AOC2, AOC3 |
GO:0052596 | MF | phenethylamine:oxygen oxidoreductase (deaminating) activity | Catalysis of the reaction: phenylethylamine + O2 + H2O = phenylacetaldehyde + NH3 + hydrogen peroxide + H+. |
AOC2, AOC3 |
GO:0052629 | MF | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity | Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate + H2O = a 1-phosphatidyl-1D-myo-inositol 5-phosphate + phosphate + 2 H+. |
SYNJ2, SYNJ1, MTM1, MTMR1, MTMR2, MTMR4 |
GO:0052642 | MF | lysophosphatidic acid phosphatase activity | Catalysis of the reaction: lysophosphatidic acid + H2O = phosphate + monoacylglycerol. |
ACPP, ACP6 |
GO:0052650 | MF | NADP-retinol dehydrogenase activity | Catalysis of the reaction: all-trans-retinol + NADP+ = all-trans-retinal + NADPH + H+. |
DHRS3, AKR1C3, RDH10, RDH13, RDH11, DHRS4 |
GO:0052651 | BP | monoacylglycerol catabolic process | The chemical reactions and pathways resulting in the breakdown of monoacylglycerol, any ester of glycerol in which any one of its hydroxyl groups has been acylated with a fatty acid, the other being non-esterified. |
ABHD12 |
GO:0052654 | MF | L-leucine transaminase activity | Catalysis of the reaction: 2-oxoglutarate + L-leucine = 4-methyl-2-oxopentanoate + L-glutamatic acid. |
BCAT1 |
GO:0052655 | MF | L-valine transaminase activity | Catalysis of the reaction: 2-oxoglutarate + L-valine = 3-methyl-2-oxobutanoic acid + L-glutamatic acid. |
BCAT1 |
GO:0052656 | MF | L-isoleucine transaminase activity | Catalysis of the reaction: 2-oxoglutarate + L-isoleucine = (S)-3-methyl-2-oxopentanoic acid + L-glutamic acid. |
BCAT1 |
GO:0052658 | MF | inositol-1,4,5-trisphosphate 5-phosphatase activity | Catalysis of the reaction: 1D-myo-inositol 1,4,5-trisphosphate + H2O = 1D-myo-inositol 1,4-bisphosphate + phosphate. |
SYNJ1, OCRL, INPP5A, INPP5K |
GO:0052659 | MF | inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity | Catalysis of the reaction: 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate. |
SYNJ1, OCRL, ITPK1, INPP5A, INPP5D, INPP5K |
GO:0052689 | MF | carboxylic ester hydrolase activity | Catalysis of the hydrolysis of a carboxylic ester bond. |
ACOT7, ACOT8, LYPLA2, CES3, NLGN4X, NLGN1, ACOT4, ABHD4, ABHD5, LIPH, FAM135A, ACOT9 |
GO:0052695 | BP | cellular glucuronidation | The modification of an organic chemical by the conjugation of glucuronic acid. The substances resulting from glucuronidation are known as glucuronosides (or glucuronides) and are often much more water-soluble than the non-glucuronic acid-containing precursor. |
UGT2B4, UGT2A3, ABHD10 |
GO:0052696 | BP | flavonoid glucuronidation | The modification of a flavonoid by the conjugation of glucuronic acid. The resultant flavonoid glucuronosides are often much more water-soluble than the precursor. |
UGT2B4, UGT2A3 |
GO:0052723 | MF | inositol hexakisphosphate 1-kinase activity | Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + 1-diphospho-1D-myo-inositol (2,3,4,5,6)pentakisphosphate. |
PPIP5K1, IP6K2 |
GO:0052724 | MF | inositol hexakisphosphate 3-kinase activity | Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + 3-diphospho-1D-myo-inositol (1,2,4,5,6)pentakisphosphate. |
PPIP5K1, IP6K2 |
GO:0052725 | MF | inositol-1,3,4-trisphosphate 6-kinase activity | Catalysis of the reaction: 1D-myo-inositol 1,3,4-trisphosphate + ATP = 1D-myo-inositol 1,3,4,6-tetrakisphosphate + ADP + 2 H(+). |
ITPK1 |
GO:0052726 | MF | inositol-1,3,4-trisphosphate 5-kinase activity | Catalysis of the reaction: 1D-myo-inositol 1,3,4-trisphosphate + ATP = 1D-myo-inositol 1,3,4,5-tetrakisphosphate + ADP + 2 H(+). |
ITPK1 |
GO:0052739 | MF | phosphatidylserine 1-acylhydrolase activity | Catalysis of the reaction: phosphatidylserine + H2O = 2-acyl-sn-glycero-3-phosphoserine + fatty acid. |
PLA2G16 |
GO:0052740 | MF | 1-acyl-2-lysophosphatidylserine acylhydrolase activity | Catalysis of the reaction: 1-acyl-2-lysophosphatidylserine + H2O = sn-glycerol-phosphoserine + a carboxylate. |
PLA2G16 |
GO:0052741 | MF | (R)-limonene 6-monooxygenase activity | Catalysis of the reaction: (4R)-limonene + H+ + NADPH + O2 = (1R,5S)-carveol + H2O + NADP+. |
CYP2C9 |
GO:0052745 | MF | inositol phosphate phosphatase activity | Catalysis of the reaction: inositol phosphate(n) + H2O = inositol phosphate(n-1) + phosphate. This reaction is the removal of a phosphate group from an inositol phosphate. |
OCRL, MINPP1 |
GO:0052794 | MF | exo-alpha-(2->3)-sialidase activity | Catalysis of the hydrolysis of alpha-(2->3)-glycosidic linkages of terminal sialic residues in substrates. |
NEU1 |
GO:0052795 | MF | exo-alpha-(2->6)-sialidase activity | Catalysis of the hydrolysis of alpha-(2->6)-glycosidic linkages of terminal sialic residues in substrates. |
NEU1 |
GO:0052796 | MF | exo-alpha-(2->8)-sialidase activity | Catalysis of the hydrolysis of alpha-(2->8)-glycosidic linkages of terminal sialic residues in substrates. |
NEU1 |
GO:0052798 | MF | beta-galactoside alpha-2,3-sialyltransferase activity | Catalysis of the transfer of sialyl residues alpha-2,3-linked to a beta galactosyl residue on the donor to form an alpha-2,3 linkage to a terminal beta galactosyl residue on the acceptor. |
ST3GAL6 |
GO:0052810 | MF | 1-phosphatidylinositol-5-kinase activity | Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol + ATP = a 1-phosphatidyl-1D-myo-inositol 5-phosphate + ADP + 2 H(+). |
PIP5K1B |
GO:0052811 | MF | 1-phosphatidylinositol-3-phosphate 4-kinase activity | Catalysis of the reaction: a 1-phosphatidyl-1D-myo-inositol 4-phosphate + ATP = a 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + ADP + 2 H(+). |
PIP5K1B, PIP5K1C, PIP4K2B |
GO:0052812 | MF | phosphatidylinositol-3,4-bisphosphate 5-kinase activity | Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + ATP = a 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate + ADP + 2 H(+). |
PIP5K1B, PIP5K1C |
GO:0052815 | MF | medium-chain acyl-CoA hydrolase activity | Catalysis of the reaction: H2O + a medium-chain acyl-CoA = a medium-chain carboxylate + CoA. A medium chain is a chain of between eight and twelve carbons in length. |
ACOT8 |
GO:0052821 | MF | DNA-7-methyladenine glycosylase activity | Catalysis of the reaction: DNA containing 7-methyladenine + H2O = DNA with abasic site + 7-methyladenine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 7-methyladenine and the deoxyribose sugar to remove the 7-methyladenine, leaving an abasic site. |
MPG |
GO:0052822 | MF | DNA-3-methylguanine glycosylase activity | Catalysis of the reaction: DNA containing 3-methylguanine + H2O = DNA with abasic site + 3-methylguanine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 3-methylguanine and the deoxyribose sugar to remove the 3-methylguanine, leaving an abasic site. |
MPG |
GO:0052825 | MF | inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity | Catalysis of the reaction: inositol-1,3,4,5,6-pentakisphosphate + H2O = inositol-3,4,5,6-tetrakisphosphate + phosphate. |
ITPK1 |
GO:0052826 | MF | inositol hexakisphosphate 2-phosphatase activity | Catalysis of the reaction: myo-inositol hexakisphosphate + H2O = myo-inositol 1,3,4,5,6-pentakisphosphate + phosphate. |
MINPP1 |
GO:0052828 | MF | inositol-3,4-bisphosphate 4-phosphatase activity | Catalysis of the reaction: 1D-myo-inositol 3,4-bisphosphate + H2O = 1D-myo-inositol 3-phosphate + phosphate. |
INPP4B, INPP4A |
GO:0052829 | MF | inositol-1,3,4-trisphosphate 1-phosphatase activity | Catalysis of the reaction: D-myo-inositol 1,3,4-trisphosphate + H2O = myo-inositol 3,4-bisphosphate + phosphate. |
INPP1 |
GO:0052830 | MF | inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity | Catalysis of the reaction: inositol-1,3,4,6-tetrakisphosphate + H2O = inositol-1,3,4-trisphosphate + phosphate. |
ITPK1 |
GO:0052831 | MF | inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity | Catalysis of the reaction: inositol-1,3,4,6-tetrakisphosphate + H2O = inositol-3,4,6-trisphosphate + phosphate. |
ITPK1 |
GO:0052832 | MF | inositol monophosphate 3-phosphatase activity | Catalysis of the reaction: myo-inositol 3-phosphate + H2O = myo-inositol + phosphate. |
IMPA1 |