| GO ID | Ontology | GO Term | Term Definition |
Proteins |
GO:0050852 | BP | T cell receptor signaling pathway | A series of molecular signals initiated by the cross-linking of an antigen receptor on a T cell. |
PSMD11, PSMD12, PIK3CD, FYB, PSMD3, MAP3K7, RIPK2, TNFRSF21, PSMD10, PAK3, BCL10, CD4, HLA-DRA, HLA-DQA2, HLA-DQA1, HLA-DQB1, FYN, PTPRC, UBC, CD28, HLA-DRB4, PLCG2, PSMC3, NFKB1, HLA-DPA1, PSMB1, PSMA1, PSMA2, PSMA3, PSMA4, PIK3R1, PSMB8, PSMB9, PSMB4, PSMB5, MAPK1, PSMC2, PSMB10, CSK, PIK3CA, PIK3CB, PSMC4, PSMB3, PSEN1, PSMD7, CACNB3, PTEN, PSME3, PSMC1, PSMC6, RPS27A, UBA52, SKP1, HLA-DRB3, RELA, PRKCQ, PDE4D, PTPRJ, PAK2, PSMD2, UBE2V1, RFTN1, PSME4, SHB, STK11, HLA-DRB5, THEMIS2, SPPL3, INPP5D, PRKD2, FOXP3, PAG1, BTRC |
GO:0050853 | BP | B cell receptor signaling pathway | A series of molecular signals initiated by the cross-linking of an antigen receptor on a B cell. |
IGLL5, PIK3CD, PRKCB, LYN, PTPRC, BCL2, PLCG2, MAPK1, MNDA, SYK, MEF2C, NFATC2, RFTN1, KLHL6, VAV3 |
GO:0050855 | BP | regulation of B cell receptor signaling pathway | Any process that modulates the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B cell. |
LYN, PTPN22 |
GO:0050856 | BP | regulation of T cell receptor signaling pathway | Any process that modulates the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell. |
BCL10 |
GO:0050857 | BP | positive regulation of antigen receptor-mediated signaling pathway | Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B- or T cell. |
PTPRC |
GO:0050859 | BP | negative regulation of B cell receptor signaling pathway | Any process that stops, prevents, or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B cell. |
LPXN, PLCL2 |
GO:0050860 | BP | negative regulation of T cell receptor signaling pathway | Any process that stops, prevents, or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell. |
PRNP, EZR, PTPN2, LGALS3, GBP1, DUSP3, PTPRJ, PAWR, DUSP22, PHPT1, PTPN22 |
GO:0050861 | BP | positive regulation of B cell receptor signaling pathway | Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B cell. |
PRKCB, LYN, CMTM3, SLC39A10 |
GO:0050862 | BP | positive regulation of T cell receptor signaling pathway | Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell. |
RAB29, ADA, PRKD2 |
GO:0050863 | BP | regulation of T cell activation | Any process that modulates the frequency, rate or extent of T cell activation. |
CD4, CCL5, PAG1 |
GO:0050865 | BP | regulation of cell activation | Any process that modulates the frequency, rate or extent of cell activation, the change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand. |
LMO4 |
GO:0050867 | BP | positive regulation of cell activation | Any process that activates or increases the frequency, rate or extent of activation. |
JAK2, CTGF |
GO:0050868 | BP | negative regulation of T cell activation | Any process that stops, prevents, or reduces the frequency, rate or extent of T cell activation. |
SOCS6, LAG3, DUSP3, JAK3, VTCN1, DUSP22, PAG1, PTPN22 |
GO:0050869 | BP | negative regulation of B cell activation | Any process that stops, prevents, or reduces the frequency, rate or extent of B cell activation. |
TNFAIP3, FAS, SAMSN1 |
GO:0050870 | BP | positive regulation of T cell activation | Any process that activates or increases the frequency, rate or extent of T cell activation. |
TNFSF11, MAP3K7, BCL10, HSPD1, CCL2, HLA-DPA1, PRKCQ, CD47, PYCARD |
GO:0050871 | BP | positive regulation of B cell activation | Any process that activates or increases the frequency, rate or extent of B cell activation. |
IGLL5, IL6, TNFSF4 |
GO:0050872 | BP | white fat cell differentiation | The process in which a relatively unspecialized cell acquires specialized features of a white adipocyte, an animal connective tissue cell involved in energy storage. White adipocytes have cytoplasmic lipids arranged in a unique vacuole. |
SNAI2, FABP4, PPARG, CTBP2, AACS, TBL1XR1 |
GO:0050873 | BP | brown fat cell differentiation | The process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria. |
LRG1, ADRB2, ADRB1, NUDT7, ADRB3, SLC2A4, FABP4, CEBPB, ITGA6, UCP1, PTGS2, RGS2, ALDH6A1, BNIP3, ADIPOQ, MRAP, ERO1A, RARRES2, EBF2, PPARGC1A |
GO:0050877 | BP | neurological system process | A organ system process carried out by any of the organs or tissues of neurological system. |
CHRNB1, KCNJ11, GPR98 |
GO:0050878 | BP | regulation of body fluid levels | Any process that modulates the levels of body fluids. |
EPHB2, PDSS2, HEG1 |
GO:0050880 | BP | regulation of blood vessel size | Any process that modulates the size of blood vessels. |
ITGB1BP1, NOS3, NTS, GCLC, GCLM, HBB, FOXC1 |
GO:0050881 | BP | musculoskeletal movement | The movement of an organism or part of an organism using mechanoreceptors, the nervous system, striated muscle and/or the skeletal system. |
GIGYF2 |
GO:0050882 | BP | voluntary musculoskeletal movement | The movement of an organism or part of an organism using mechanoreceptors, the nervous system, striated muscle and/or the skeletal system that can be controlled at will. |
ITPR1, HIPK2 |
GO:0050883 | BP | musculoskeletal movement, spinal reflex action | Involuntary movement caused by the application of a stimulus to an organism and a subsequent movement. The signal processing of this movement takes place in the spinal cord. |
ASCL1 |
GO:0050884 | BP | neuromuscular process controlling posture | Any process in which an organism voluntarily modulates its posture, the alignment of its anatomical parts. |
GAA, TCF15, PNKD |
GO:0050885 | BP | neuromuscular process controlling balance | Any process that an organism uses to control its balance, the orientation of the organism (or the head of the organism) in relation to the source of gravity. In humans and animals, balance is perceived through visual cues, the labyrinth system of the inner ears and information from skin pressure receptors and muscle and joint receptors. |
TPP1, RBFOX2, NBN, APP, GAA, BCR, GM2A, SLC1A3, ALDH1A3, RAC3, DLG4, ABR, CLN3, GIGYF2, NR4A3, TNR, CLIC5, NRXN1, CAMTA1 |
GO:0050890 | BP | cognition | The operation of the mind by which an organism becomes aware of objects of thought or perception; it includes the mental activities associated with thinking, learning, and memory. |
SOBP, CHL1, HLA-DRA, LHCGR, ADORA1, CHRNA7, SLC1A4, HOXA1, GNAS, ST3GAL4, GNAS, NIPBL, CYFIP1, LINS1, RP9, PTCHD1, CHD7, GTF2A1L, HRH3 |
GO:0050891 | BP | multicellular organismal water homeostasis | Any process involved in the maintenance of an internal steady state of water within a tissue, organ, or a multicellular organism. |
SCNN1A, SCNN1G, TRPV4 |
GO:0050892 | BP | intestinal absorption | Any process in which nutrients are taken up from the contents of the intestine. |
VDR, CD36, LEP, SCARB1, TJP2, F11R |
GO:0050893 | BP | sensory processing | Any neural process required for an organism to sense and interpret the dimensions of a sensory experience: modality, location, intensity and affect. |
TTC8 |
GO:0050896 | BP | response to stimulus | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism. |
PDE6D, MIP, SCNN1A, PPT1, SCNN1G, TGFBI, FAM161A, CYP4V2, ZNF513, BBS1, WDR36, BBS10, RPGR, HPS1, SPATA7, SLC45A2 |
GO:0050897 | MF | cobalt ion binding | Interacting selectively and non-covalently with a cobalt (Co) ion. |
NUDT16 |
GO:0050900 | BP | leukocyte migration | The movement of a leukocyte within or between different tissues and organs of the body. |
ANGPT2, SLC16A3, GPR32, F2, NRAS, KRAS, COL1A1, FN1, MMP1, APOB, CD74, ATP1B1, ITGB3, ITGB2, ICAM1, ITGB1, FYN, ITGAV, LYN, COL1A2, SLC3A2, ITGA5, CD48, ITGAM, SELL, MIF, MMP9, B4GALT1, CD44, PECAM1, SELE, CD58, ITGAX, MAG, FPR1, C5AR1, ITGA6, FPR2, ITGA3, PIK3R1, MYH9, BSG, PIK3CA, PIK3CB, ATP1B3, F2RL1, JAM2, PPIA, GRB2, CXADR, SIRPA, OLR1, SLC7A9, SLC7A5, TEK, CAV1, PTPN11, SOS1, CD47, MERTK, PPIL2, SELPLG, GAS6, GRB14, ANGPT1, CD177, SLC7A6, INPP5D, GLG1, JAM3, CD244, TREM1, SLC7A8, SLC7A7, PROCR, SLC7A11, F11R |
GO:0050901 | BP | leukocyte tethering or rolling | Transient adhesive interactions between leukocytes and endothelial cells lining blood vessels. Carbohydrates on circulating leukocytes bind selectins on the vessel wall causing the leukocytes to slow down and roll along the inner surface of the vessel wall. During this rolling motion, transitory bonds are formed and broken between selectins and their ligands. Typically the first step in cellular extravasation (the movement of leukocytes out of the circulatory system, towards the site of tissue damage or infection). |
TNF, ITGB1, SELE, VCAM1, LEP |
GO:0050902 | BP | leukocyte adhesive activation | The activation of loosely bound or rolling leukocytes by signals displayed on blood vessel endothelial cells, which is typically the second step in cellular extravasation. |
SELPLG |
GO:0050904 | BP | diapedesis | The passage of a leukocyte between the tight junctions of endothelial cells lining blood vessels, typically the fourth and final step of cellular extravasation. |
PECAM1 |
GO:0050905 | BP | neuromuscular process | Any process pertaining to the functions of the nervous and muscular systems of an organism. |
UCHL1, HOXD10, HOXA1, FGF12, KCNA1, SPG20, AGTPBP1 |
GO:0050908 | BP | detection of light stimulus involved in visual perception | The series of events involved in visual perception in which a light stimulus is received and converted into a molecular signal. |
GRM6, BEST1, EYS |
GO:0050909 | BP | sensory perception of taste | The series of events required for an organism to receive a gustatory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Gustation involves the direct detection of chemical composition, usually through contact with chemoreceptor cells. This is a neurological process. |
CD36, SCNN1A, SCNN1G, GNB1 |
GO:0050910 | BP | detection of mechanical stimulus involved in sensory perception of sound | The series of events involved in the perception of sound vibration in which the vibration is received and converted into a molecular signal. |
KIT, COL11A1, MKKS |
GO:0050911 | BP | detection of chemical stimulus involved in sensory perception of smell | The series of events involved in the perception of smell in which an olfactory chemical stimulus is received and converted into a molecular signal. |
OR3A3, OR52E8, OR5A2, OR5L2, OR14C36, OR2A5, OR51E2 |
GO:0050913 | BP | sensory perception of bitter taste | The series of events required to receive a bitter taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. |
ITPR3 |
GO:0050915 | BP | sensory perception of sour taste | The series of events required to receive a sour taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. |
ASIC2, ASIC3 |
GO:0050916 | BP | sensory perception of sweet taste | The series of events required to receive a sweet taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. |
ITPR3 |
GO:0050917 | BP | sensory perception of umami taste | The series of events required to receive an umami taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. Umami taste is the savory taste of meats and other foods that are rich in glutamates. This is a neurological process. |
ITPR3 |
GO:0050918 | BP | positive chemotaxis | The directed movement of a motile cell or organism towards a higher concentration of a chemical. |
NRP1, PDGFB, MET, FGF2, HMGB1, SAA1, SAA2, CCL3, BMP4, CCL5, SCG2, MIF, HGF, VEGFA, LGALS3, FGF7, HMGB2, CORO1A, CXCL12, VEGFC, TSC2, PTPRJ, SEMA5A, ALKBH1, ANGPT1 |
GO:0050919 | BP | negative chemotaxis | The directed movement of a motile cell or organism towards a lower concentration of a chemical. |
SEMA3E, FLRT2, SLIT2, SEMA3D, APOA1, PDGFA, ITGB3, ITGAV, PLXNA3, EFNA5, RHOA, SEMA3B, SEMA5A, SEMA3A, SEMA6D, SEMA3C, SEMA6A, SEMA4A, SEMA6B, FLRT3 |
GO:0050920 | BP | regulation of chemotaxis | Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient. |
PDGFRA, EFNB2, CXCR4 |
GO:0050921 | BP | positive regulation of chemotaxis | Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient. |
PDGFB, TGFB1, THBS1, PDGFRB, PPM1F, F2RL1, STX4, STX3, RARRES2 |
GO:0050922 | BP | negative regulation of chemotaxis | Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient. |
PTPN2 |
GO:0050925 | BP | negative regulation of negative chemotaxis | Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical. |
ROBO2 |
GO:0050927 | BP | positive regulation of positive chemotaxis | Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical. |
VEGFA, ITGA2, S1PR1, F2RL1, CDH13, SMAD3 |
GO:0050928 | BP | negative regulation of positive chemotaxis | Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical. |
ANGPT2 |
GO:0050929 | BP | induction of negative chemotaxis | Any process that initiates the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical. |
SLIT2 |
GO:0050930 | BP | induction of positive chemotaxis | Any process that initiates the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical. |
CXCL8, SCG2, VEGFA, CXCL12, PGF, VEGFC |
GO:0050942 | BP | positive regulation of pigment cell differentiation | Any process that activates or increases the frequency, rate or extent of pigment cell differentiation. |
BLOC1S6 |
GO:0050951 | BP | sensory perception of temperature stimulus | The series of events required for an organism to receive a sensory temperature stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. |
BTBD9 |
GO:0050953 | BP | sensory perception of light stimulus | The series of events required for an organism to receive a sensory light stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. |
GPR98 |
GO:0050954 | BP | sensory perception of mechanical stimulus | The series of events required for an organism to receive a sensory mechanical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. |
TRPV1 |
GO:0050955 | BP | thermoception | The series of events required for an organism to receive a temperature stimulus, convert it to a molecular signal, and recognize and characterize the signal. Thermoception in larger animals is mainly done in the skin; mammals have at least two types of sensor, for detecting heat (temperatures above body temperature) and cold (temperatures below body temperature). |
TRPV1 |
GO:0050960 | BP | detection of temperature stimulus involved in thermoception | The series of events in which a temperature stimulus is received and converted into a molecular signal as part of thermoception. |
TRPV1 |
GO:0050965 | BP | detection of temperature stimulus involved in sensory perception of pain | The series of events involved in the perception of pain in which a temperature stimulus is received and converted into a molecular signal. |
NTRK1, ADORA1, EPHB1, TRPV1, LXN, ASIC3, MMP24 |
GO:0050966 | BP | detection of mechanical stimulus involved in sensory perception of pain | The series of events involved in the perception of pain in which a mechanical stimulus is received and converted into a molecular signal. |
NTRK1, FYN, ITGA2, KCNA1, ASIC3 |
GO:0050968 | BP | detection of chemical stimulus involved in sensory perception of pain | The series of events involved in the perception of pain in which a chemical stimulus is received and converted into a molecular signal. |
TRPV1, ASIC3 |
GO:0050974 | BP | detection of mechanical stimulus involved in sensory perception | The series of events in which a mechanical stimulus is received and converted into a molecular signal as part of sensory perception. |
SERPINE2, ASIC2 |
GO:0050976 | BP | detection of mechanical stimulus involved in sensory perception of touch | The series of events involved in the perception of touch in which a mechanical stimulus is received and converted into a molecular signal. |
KCNA1 |
GO:0050982 | BP | detection of mechanical stimulus | The series of events by which a mechanical stimulus is received and converted into a molecular signal. |
JUP, PKD1, PKD2, DENND5A, DENND5B |
GO:0050983 | BP | deoxyhypusine biosynthetic process from spermidine | The chemical reactions resulting in the formation of deoxyhypusine from spermidine by the enzyme [eIF-5A]-deoxyhypusine synthase. The reaction occurs in four steps: 1. spermidine + NAD+ = dehydrospermidine + NADH + H+; 2. dehydrospermidine + [enzyme]-lysine = 1,3-diaminopropane + [enzyme]-lysine-N6=CH(CH2)3NH2; 3. [enzyme]-lysine-N6=CH(CH2)3NH2 = [eIF-5A]-lysine-N6=CH(CH2)3NH2; 4. [eIF-5A]-lysine-N6=CH(CH2)3NH2 + NADH + H+ = [eIF-5A]-deoxyhypusine + NAD+. |
DHPS |
GO:0050992 | BP | dimethylallyl diphosphate biosynthetic process | The chemical reactions and pathways resulting in the formation of dimethylallyl diphosphate. |
IDI1, IDI2 |
GO:0050994 | BP | regulation of lipid catabolic process | Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of lipids. |
THRA, LGALS12, RARRES2 |
GO:0050995 | BP | negative regulation of lipid catabolic process | Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids. |
INS, TNF, IL1B, APOA2, APOC1, APOC3, ADORA1, PDE3B, CRTC3, C7orf55 |
GO:0050996 | BP | positive regulation of lipid catabolic process | Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids. |
IL1B, APOA2, APOA5 |
GO:0050998 | MF | nitric-oxide synthase binding | Interacting selectively and non-covalently with the enzyme nitric-oxide synthase. |
CD74, DMD, ATP2B4, ACTB, CALM2, CAV1, SNTA1, CAMK2D |
GO:0050999 | BP | regulation of nitric-oxide synthase activity | Any process that modulates the activity of the enzyme nitric-oxide synthase. |
WASL, LYPLA1, DDAH1, DDAH2, EGFR, IL1B, HSP90AA1, ACVR2A, NOS3, AKT1, LEP, CALM2, CAV1, NOSTRIN, CYGB |
GO:0051000 | BP | positive regulation of nitric-oxide synthase activity | Any process that activates or increases the activity of the enzyme nitric-oxide synthase. |
DHFR, KRAS, INS, APOE, NPR3, AKT1, HTR2B, AGTR2, CALM2, HIF1A, SCARB1 |
GO:0051001 | BP | negative regulation of nitric-oxide synthase activity | Any process that stops or reduces the activity of the enzyme nitric-oxide synthase. |
CNR1, ATP2B4, CAV1 |
GO:0051005 | BP | negative regulation of lipoprotein lipase activity | Any process that stops or reduces the activity of the enzyme lipoprotein lipase. |
APOC1, APOC3 |
GO:0051006 | BP | positive regulation of lipoprotein lipase activity | Any process that activates or increases the activity of the enzyme lipoprotein lipase. |
APOA1, APOH, NR1H2, NR1H3, APOA5, ABHD5, LMF1 |
GO:0051010 | MF | microtubule plus-end binding | Interacting selectively and non-covalently with the plus end of a microtubule. |
APC, CLIP1, DST, MAPRE1, KIF18A, KIF2C, CLIP2 |
GO:0051011 | MF | microtubule minus-end binding | Interacting selectively and non-covalently with the minus end of a microtubule. |
CAMSAP2, TUBGCP3, CAMSAP3 |
GO:0051013 | BP | microtubule severing | The process in which a microtubule is broken down into smaller segments. |
KATNB1, KATNAL1, SPAST |
GO:0051014 | BP | actin filament severing | The process in which an actin filament is broken down into smaller filaments. |
DSTN |
GO:0051015 | MF | actin filament binding | Interacting selectively and non-covalently with an actin filament, also known as F-actin, a helical filamentous polymer of globular G-actin subunits. |
WIPF3, BIN1, ARPC2, ARPC3, ACTN4, WDR1, NEBL, MYO1D, EGFR, ACTN1, MYL4, EEF2, LCP1, EZR, FLNA, CFL1, CTNNA2, TMOD1, SSFA2, MARCKS, CORO1A, CTNNA1, MYH9, ACTN2, MYH11, ABL2, CAPZB, ARPC4, DSTN, ACTR3, ACTR2, NEXN, MYO1E, IQGAP2, SHROOM2, FLNC, PLS1, FSCN1, CYFIP1, ADSSL1, SHROOM3, SYNE2, TTN, CORO2A, AJUBA, PANX1, AIF1L, CORO1B, TRIOBP, TRPV4, MYO10, CTNNAL1, LIMA1, BLOC1S6, CORO1C, MYO6, MACF1, TLN1 |
GO:0051016 | BP | barbed-end actin filament capping | The binding of a protein or protein complex to the barbed (or plus) end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits. |
RDX, CAPG, CAPZB, CAPZA1, TWF1, EPS8, TWF2, TRIOBP |
GO:0051017 | BP | actin filament bundle assembly | The assembly of actin filament bundles; actin filaments are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness. |
RHOD, ACTN4, ACTN1, LCP1, EZR, CDC42, EPS8, DPYSL3, NEDD9, PLS1, FSCN1, PAWR, CORO1B, LIMA1, BAIAP2L1 |
GO:0051018 | MF | protein kinase A binding | Interacting selectively and non-covalently with any subunit of protein kinase A. |
RDX, AKAP13, AKAP6, SPHKAP, MYRIP, DACT3, DACT1, AKAP7, AKAP11, AKAP2 |
GO:0051019 | MF | mitogen-activated protein kinase binding | Interacting selectively and non-covalently with a mitogen-activated protein kinase. |
TPR, ACE, ATF7, PTAFR, IQGAP1, GTF2I, DUSP2, PTPRJ, MAPK7, NBR1 |
GO:0051020 | MF | GTPase binding | Interacting selectively and non-covalently with a GTPase, any enzyme that catalyzes the hydrolysis of GTP. |
ENO1, EPRS, HSP90AA1, LCP1, GNB3, RASA1, FLNA, GNB1, GNB2, YBX1, SPTBN1, BNIP3, GOLGA4 |
GO:0051022 | MF | Rho GDP-dissociation inhibitor binding | Interacting selectively and non-covalently with a Rho GDP-dissociation inhibitor protein. |
HSP90AA1, CDC42, RAC1 |
GO:0051023 | BP | regulation of immunoglobulin secretion | Any process that modulates the frequency, rate or extent of the regulated release of immunoglobulins from a cell. |
TNF, CD40LG |
GO:0051024 | BP | positive regulation of immunoglobulin secretion | Any process that activates or increases the frequency, rate or extent of the regulated release of immunoglobulins from a cell. |
IL33, RBP4, IL6, HLA-E, XBP1, TNFSF4, STX4 |
GO:0051025 | BP | negative regulation of immunoglobulin secretion | Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of immunoglobulins from a cell. |
IL33 |
GO:0051026 | BP | chiasma assembly | The cell cycle process in which a connection between chromatids assembles, indicating where an exchange of homologous segments has taken place by the crossing-over of non-sister chromatids. |
UBE2B |
GO:0051028 | BP | mRNA transport | The directed movement of mRNA, messenger ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
MYO1C, IGF2BP3, XPO1, KIF5C, TNKS, HNRNPA1, ZFP36, LRPPRC, HNRNPA3, SEC13, FMR1, ZFP36L1, SLBP, NCBP3, SUPT6H, AHCTF1, KHSRP, QKI, EIF5A2, UPF3A, PARP11, G3BP2, NPIPA1, IGF2BP2 |
GO:0051033 | MF | RNA transmembrane transporter activity | Enables the transfer of RNA, ribonucleic acid, from one side of a membrane to the other. |
HNRNPA3 |
GO:0051036 | BP | regulation of endosome size | Any process that modulates the volume of an endosome, a membrane-bounded organelle that carries materials newly ingested by endocytosis. |
RAB5A, ALS2 |
GO:0051042 | BP | negative regulation of calcium-independent cell-cell adhesion | Any process that stops, prevents, or reduces the frequency, rate or extent of calcium-independent cell-cell adhesion. |
BMP2 |
GO:0051044 | BP | positive regulation of membrane protein ectodomain proteolysis | Any process that activates or increases the frequency, rate or extent of membrane protein ectodomain peptidolysis. |
NRDC, TNF, IL1B, APOE, FURIN, TNFRSF1B, ADAM8, GPLD1, ADAM9, SNX33, SNX9 |
GO:0051045 | BP | negative regulation of membrane protein ectodomain proteolysis | Any process that stops, prevents, or reduces the frequency, rate or extent of membrane protein ectodomain proteolysis. |
TIMP1, TIMP2, IL10, TIMP3 |
GO:0051046 | BP | regulation of secretion | Any process that modulates the frequency, rate or extent of the controlled release of a substance from a cell or a tissue. |
MYO6 |