| GO ID | Ontology | GO Term | Term Definition |
Proteins |
GO:0047256 | MF | lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity | Catalysis of the reaction: cytolipin-H + UDP-N-acetyl-D-glucosamine = N-acetyl-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide + UDP. |
B3GNT5 |
GO:0047280 | MF | nicotinamide phosphoribosyltransferase activity | Catalysis of the reaction: diphosphate + nicotinamide mononucleotide = 5-phospho-alpha-D-ribose 1-diphosphate + H(+) + nicotinamide. |
NAMPT |
GO:0047288 | MF | monosialoganglioside sialyltransferase activity | Catalysis of the reaction: D-galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide + CMP-N-acetylneuraminate = N-acetylneuraminyl-D-galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide + CMP. |
ST3GAL4 |
GO:0047290 | MF | (alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl-galactosaminide 6-alpha-sialyltransferase activity | Catalysis of the reaction: alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-D-galactosaminyl-R + CMP-N-acetyl-beta-neuraminate = alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-(1->3)-[N-acetyl-alpha-neuraminyl-(2->6)]-N-acetyl-D-galactosaminyl-R + CMP. |
ST6GALNAC4 |
GO:0047293 | MF | 4-hydroxybenzoate nonaprenyltransferase activity | Catalysis of the reaction: p-hydroxybenzoate + solanesyl pyrophosphate = nonaprenyl-4-hydroxybenzoate + diphosphate. |
COQ2 |
GO:0047298 | MF | (S)-3-amino-2-methylpropionate transaminase activity | Catalysis of the reaction: (S)-3-amino-2-methylpropanoate + 2-oxoglutarate = 2-methyl-3-oxopropanoate + L-glutamate. |
ABAT |
GO:0047322 | MF | [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity | Catalysis of the reaction: [3-hydroxy-3-methylglutaryl-CoA reductase (NADPH)] + ATP = [3-hydroxy-3-methylglutaryl-CoA reductase (NADPH)] phosphate + ADP. |
PRKAA2 |
GO:0047325 | MF | inositol tetrakisphosphate 1-kinase activity | Catalysis of the reaction: 1D-myo-inositol 3,4,5,6-tetrakisphosphate + ATP = 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP. |
ITPK1 |
GO:0047372 | MF | acylglycerol lipase activity | Catalysis of the reaction: H2O + acylglycerol = a fatty acid + glycerol. |
ABHD12, DAGLB, MGLL, ABHD6 |
GO:0047391 | MF | alkylglycerophosphoethanolamine phosphodiesterase activity | Catalysis of the reaction: H2O + 1-alkyl-sn-glycero-3-phosphoethanolamine = ethanolamine + 1-alkyl-sn-glycerol 3-phosphate. |
GNB1, ENPP2 |
GO:0047395 | MF | glycerophosphoinositol glycerophosphodiesterase activity | Catalysis of the reaction: 1-(sn-glycero-3-phospho)-1D-myo-inositol + H(2)O = sn-glycerol 3-phosphate + myo-inositol + H(+). |
GDE1 |
GO:0047429 | MF | nucleoside-triphosphate diphosphatase activity | Catalysis of the reaction: H2O + a nucleoside triphosphate = diphosphate + a nucleotide. |
ENPP3, ENPP1, DCTPP1, NUDT15 |
GO:0047442 | MF | 17-alpha-hydroxyprogesterone aldolase activity | Catalysis of the reaction: 17-alpha-hydroxyprogesterone = acetaldehyde + 4-androstene-3,17-dione. |
CYP17A1 |
GO:0047451 | MF | 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity | Catalysis of the reaction: (3R)-3-hydroxyoctanoyl-[acyl-carrier protein] = H2O + 2-octenoyl-[acyl-carrier protein]. |
FASN |
GO:0047453 | MF | ATP-dependent NAD(P)H-hydrate dehydratase activity | Catalysis of the reaction: (6S)-6beta-hydroxy-1,4,5,6-tetrahydronicotinamide adenine dinucleotide + ATP = ADP + 3 H(+) + NADH + phosphate. |
CARKD |
GO:0047484 | BP | regulation of response to osmotic stress | Any process that modulates the rate or extent of the response to osmotic stress. |
TRPV4 |
GO:0047485 | MF | protein N-terminus binding | Interacting selectively and non-covalently with a protein N-terminus, the end of any peptide chain at which the 2-amino (or 2-imino) function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue. |
HAX1, EXOC5, SDCBP, ACTN4, SYNGR3, NBN, PEX14, ZWINT, TGFB1, VWF, TP53, DCN, SCT, PARP1, ERCC2, GLRX, PPP1CC, SNCA, ID1, SMARCA4, STXBP1, RPS21, EIF5A, MAP2K1, RELA, HDAC1, GTF2H2, NPAT, ACOX1, TAF11, NCOA1, NIPBL, ERCC4, SMARCC1, EXOC4, PDLIM5, EXOC2, PHB2, FEZ1, PDCD10, TBL1XR1, KCNIP2, MORF4L1, SRRM2, NCOR2, NCOA3 |
GO:0047493 | MF | ceramide cholinephosphotransferase activity | Catalysis of the reaction: CDP-choline + ceramide = CMP + H(+) + sphingomyelin. |
SGMS1, SGMS2 |
GO:0047496 | BP | vesicle transport along microtubule | The directed movement of a vesicle along a microtubule, mediated by motor proteins. This process begins with the attachment of a vesicle to a microtubule, and ends when the vesicle reaches its final destination. |
DYNC1I1, HTT, VAMP7, RAB1A, CLN3, NDEL1, NDE1 |
GO:0047497 | BP | mitochondrion transport along microtubule | The directed movement of a mitochondrion along a microtubule, mediated by motor proteins. |
KIF1B, MAPT, LRPPRC, MAP1B, UXT |
GO:0047498 | MF | calcium-dependent phospholipase A2 activity | Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate. This reaction requires Ca2+. |
PLA2G2A, PLA2G5, PLA2G4A, PLA2G12A |
GO:0047499 | MF | calcium-independent phospholipase A2 activity | Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate. This reaction does not require Ca2+. |
PLA2G7, PNPLA8, PLA2G4C |
GO:0047522 | MF | 15-oxoprostaglandin 13-oxidase activity | Catalysis of the reaction: (5Z)-(15S)-11-alpha-hydroxy-9,15-dioxoprostanoate + NAD(P)+ -> (5Z)-(15S)-11-alpha-hydroxy-9,15-dioxoprosta-13-enoate + NAD(P)H + H+. |
PTGR1 |
GO:0047555 | MF | 3',5'-cyclic-GMP phosphodiesterase activity | Catalysis of the reaction: guanosine 3',5'-cyclic phosphate + H2O = guanosine 5'-phosphate. |
PDE5A, PDE9A, PDE3B, PDE3A |
GO:0047598 | MF | 7-dehydrocholesterol reductase activity | Catalysis of the reaction: cholesterol + NADP+ = cholesta-5,7-dien-3-beta-ol + NADPH + H+. |
DHCR7 |
GO:0047617 | MF | acyl-CoA hydrolase activity | Catalysis of the reaction: acyl-CoA + H2O = CoA + a carboxylate. |
NUDT19, ACOT7, ACOT8, THEM4, ACOT4, ACOT13, ACOT9 |
GO:0047631 | MF | ADP-ribose diphosphatase activity | Catalysis of the reaction: ADP-ribose + H2O = AMP + D-ribose 5-phosphate. |
NUDT9, NUDT5 |
GO:0047638 | MF | albendazole monooxygenase activity | Catalysis of the reaction: albendazole + H(+) + NADPH + O(2) = albendazole S-oxide + H(2)O + NADP(+). |
CYP3A4 |
GO:0047676 | MF | arachidonate-CoA ligase activity | Catalysis of the reaction: arachidonate + ATP + CoA = AMP + arachidonoyl-CoA + diphosphate + H(+). |
ACSL4 |
GO:0047693 | MF | ATP diphosphatase activity | Catalysis of the reaction: ATP + H2O = AMP + diphosphate. |
NUDT1 |
GO:0047696 | MF | beta-adrenergic receptor kinase activity | Catalysis of the reaction: ATP + beta-adrenergic receptor = ADP + phospho-beta-adrenergic receptor. |
GRK5, ADRBK2, GRK6 |
GO:0047704 | MF | bile-salt sulfotransferase activity | Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + taurolithocholate = adenosine 3',5'-bisphosphate + taurolithocholate sulfate. |
SULT2A1 |
GO:0047710 | MF | bis(5'-adenosyl)-triphosphatase activity | Catalysis of the reaction: P(1),P(3)-bis(5'-adenosyl) triphosphate + H(2)O = ADP + AMP + 2 H(+). |
FHIT, ENPP4 |
GO:0047718 | MF | indanol dehydrogenase activity | Catalysis of the reaction: indan-1-ol + NAD(P)+ = indanone + NAD(P)H + H+. |
AKR1C3, AKR1C1 |
GO:0047750 | MF | cholestenol delta-isomerase activity | Catalysis of the reaction: 5-alpha-cholest-7-en-3-beta-ol = 5-alpha-cholest-8-en-3-beta-ol. |
EBP, EBPL |
GO:0047751 | MF | cholestenone 5-alpha-reductase activity | Catalysis of the reaction: 5alpha-cholestan-3-one + NADP(+) = cholest-4-en-3-one + H(+) + NADPH. |
SRD5A1, SRD5A2 |
GO:0047756 | MF | chondroitin 4-sulfotransferase activity | Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 4'-sulfate. |
CHST11 |
GO:0047757 | MF | chondroitin-glucuronate 5-epimerase activity | Catalysis of the reaction: chondroitin D-glucuronate = dermatan L-iduronate. |
DSEL, DSE |
GO:0047760 | MF | butyrate-CoA ligase activity | Catalysis of the reaction: ATP + an acid + CoA = AMP + diphosphate + an acyl-CoA. |
ACSM3, AACS |
GO:0047783 | MF | corticosterone 18-monooxygenase activity | Catalysis of the reaction: corticosterone + reduced adrenal ferredoxin + O2 = 18-hydroxycorticosterone + oxidized adrenal ferredoxin + H2O. |
CYP11B1, CYP11B2 |
GO:0047787 | MF | delta4-3-oxosteroid 5beta-reductase activity | Catalysis of the reactions: (1) 5beta-cholestan-3-one + NADP+ = cholest-4-en-3-one + NADPH + H+ and (2) 17,21-dihydroxy-5beta-pregnane-3,11,20-trione + NADP+ = cortisone + NADPH + H+. |
AKR1C3 |
GO:0047840 | MF | dCTP diphosphatase activity | Catalysis of the reaction: dCTP + H2O = dCMP + diphosphate. |
DCTPP1 |
GO:0047844 | MF | deoxycytidine deaminase activity | Catalysis of the reaction: deoxycytidine + H2O = deoxyuridine + NH3. |
APOBEC3G, APOBEC3B |
GO:0047860 | MF | diiodophenylpyruvate reductase activity | Catalysis of the reaction: 3-(3,5-diiodo-4-hydroxyphenyl)lactate + NAD(+) = 3-(3,5-diiodo-4-hydroxyphenyl)pyruvate + H(+) + NADH. |
MDH1 |
GO:0047865 | MF | dimethylglycine dehydrogenase activity | Catalysis of the reaction: N,N-dimethylglycine + electron-transfer flavoprotein + H2O = sarcosine + formaldehyde + reduced electron-transfer flavoprotein. |
DMGDH |
GO:0047888 | MF | fatty acid peroxidase activity | Catalysis of the reaction: 2 H(2)O(2) + H(+) + palmitate = CO(2) + 3 H(2)O + pentadecanal. |
CYGB |
GO:0047915 | MF | ganglioside galactosyltransferase activity | Catalysis of the reaction: UDP-galactose + N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-1,4-beta-D-glucosyl-N-acylsphingosine = UDP + D-galactosyl-1,3-beta-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosyl-N-acylsphingosine. |
B3GALT4 |
GO:0047936 | MF | glucose 1-dehydrogenase [NAD(P)] activity | Catalysis of the reaction: beta-D-glucose + NAD(P)+ = D-glucono-1,5-lactone + NAD(P)H. |
H6PD |
GO:0047977 | MF | hepoxilin-epoxide hydrolase activity | Catalysis of the reaction: (5Z,9E,14Z)-(8x,11R,12S)-11,12-epoxy-8-hydroxyicosa-5,9,14-trienoate + H2O = (5Z,9E,14Z)-(8x,11x,12S)-8,11,12-trihydroxyicosa-5,9,14-trienoate. |
ALOX15 |
GO:0047982 | MF | homocysteine desulfhydrase activity | Catalysis of the reaction: L-homocysteine + H2O = sulfide + NH3 + 2-oxobutanoate. |
CTH |
GO:0047988 | MF | hydroxyacid-oxoacid transhydrogenase activity | Catalysis of the reaction: (S)-3-hydroxybutanoate + 2-oxoglutarate = acetoacetate + (R)-2-hydroxyglutarate. |
ADHFE1 |
GO:0048002 | BP | antigen processing and presentation of peptide antigen | The process in which an antigen-presenting cell expresses peptide antigen in association with an MHC protein complex on its cell surface, including proteolysis and transport steps for the peptide antigen both prior to and following assembly with the MHC protein complex. The peptide antigen is typically, but not always, processed from an endogenous or exogenous protein. |
CTSS, SLC11A1 |
GO:0048006 | BP | antigen processing and presentation, endogenous lipid antigen via MHC class Ib | The process in which an antigen-presenting cell expresses lipid antigen of endogenous origin in association with an MHC class Ib protein complex on its cell surface. Class Ib here refers to non-classical class I molecules, such as those of the CD1 family. |
CD1D |
GO:0048007 | BP | antigen processing and presentation, exogenous lipid antigen via MHC class Ib | The process in which an antigen-presenting cell expresses lipid antigen of exogenous origin in association with an MHC class Ib protein complex on its cell surface. Class Ib here refers to non-classical class I molecules, such as those of the CD1 family. |
AP3D1, CD1D |
GO:0048008 | BP | platelet-derived growth factor receptor signaling pathway | The series of molecular signals generated as a consequence of a platelet-derived growth factor receptor binding to one of its physiological ligands. |
PIK3C2A, NRP1, JAK2, ZFAND5, PLAT, PDGFB, PDGFA, PDGFRB, BCR, PDGFRA, IQGAP1, PTEN, PTPN11, PTPRJ, MYO1E, GAB1, RAPGEF1, ARID5B, CSRNP1, PDGFD, TXNIP, PDGFC |
GO:0048009 | BP | insulin-like growth factor receptor signaling pathway | The series of molecular signals generated as a consequence of the insulin-like growth factor receptor binding to one of its physiological ligands. |
IGF1, IGF1R, GHR, IGF2R, PIK3R1, AKT1, IRS1, TSC2, GRB10, GIGYF2, PLCB1, CRIM1 |
GO:0048010 | BP | vascular endothelial growth factor receptor signaling pathway | Any series of molecular signals initiated by the binding of an extracellular ligand to a vascular endothelial growth factor receptor (VEGFR) located on the surface of the receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription. |
NRP1, MAPK13, NRP2, ROCK2, HSPB1, CYBB, ITGB3, FYN, ITGAV, HSP90AA1, CCL2, VAV1, VEGFA, NCF2, PIK3R1, FLT4, PIK3CA, PIK3CB, MAPKAPK2, PGF, VEGFB, VEGFC, ACTB, CDC42, RHOA, RAC1, ACTG1, SHC2, PTK2, FOXC1, PAK2, BMPR2, NCF4, PRKD1, SHB, MAPK14, CYFIP1, SULF1, ABI1, ELMO1, CYFIP2, PRKD2, VAV3, WASF2 |
GO:0048011 | BP | neurotrophin TRK receptor signaling pathway | A series of molecular signals initiated by the binding of a neurotrophin to a receptor on the surface of the target cell where the receptor possesses tyrosine kinase activity, and ending with regulation of a downstream cellular process, e.g. transcription. |
NGF, RAF1, NTRK1, NGFR, PTPN11, SOS1, DDIT4 |
GO:0048012 | BP | hepatocyte growth factor receptor signaling pathway | The series of molecular signals generated as a consequence of the hepatocyte growth factor receptor binding to one of its physiological ligands. |
NRP1, MET, HGF, MST1, SIRT2, MUC20 |
GO:0048013 | BP | ephrin receptor signaling pathway | The series of molecular signals generated as a consequence of an ephrin receptor binding to an ephrin. |
WASL, SDCBP, ADAM10, ARPC2, ARPC3, ROCK2, PAK3, AP2A2, NTRK1, FYN, LYN, MMP2, MMP9, CHN1, MYL12A, EFNA1, RASA1, EPHA3, EPHB2, SDC2, PSEN2, EFNA4, EFNB2, EFNA5, AP2S1, EPHA5, EPHB4, EPHB1, EPHA4, ARPC4, ACTB, CDC42, ACTR3, ACTR2, RHOA, RAC1, AP2B1, ACTG1, PTK2, PTPN11, TIAM1, ARHGEF7, ITSN1, ARHGEF28, APH1B, ANKS1A, APH1A, AP2M1, EPHA6, VAV3, GIT1 |
GO:0048014 | BP | Tie signaling pathway | The series of molecular signals generated as a consequence of a Tie protein (a receptor) binding to one of its physiological ligands (an angiopoietin). |
ANGPT2, TEK, ANGPT1 |
GO:0048015 | BP | phosphatidylinositol-mediated signaling | A series of molecular signals in which a cell uses a phosphatidylinositol-mediated signaling to convert a signal into a response. Phosphatidylinositols include phosphatidylinositol (PtdIns) and its phosphorylated derivatives. |
PIK3CD, PIK3C2A, EREG, OGT, FGF18, FGF19, EGFR, PDGFB, NGF, PDGFA, ERBB2, NTRK1, IGF1, FYN, CSF1R, IGF1R, FGF2, PDGFRB, KIT, CD28, FGFR1, EZR, VAV1, PDGFRA, NPR3, KITLG, ZP3, FGF7, FGFR2, ERBB3, PTAFR, PIK3R1, FGF9, AKT1, BTC, CA8, IRS1, PIK3CA, PIK3CB, PTEN, RHOA, NCS1, GRB2, MUC5AC, NRG1, PTPN11, GAB1, ERBB4, RICTOR, TNRC6A, PIK3C3, FRS2, HBEGF, MAPKAP1, MLST8, TNRC6C, AGO4, EXOC1, PI4KB, KL, AGO2, TNRC6B, IRS2 |
GO:0048016 | BP | inositol phosphate-mediated signaling | Any intracellular signal transduction in which the signal is passed on within the cell via an inositol phosphate. Includes production of the inositol phosphate, and downstream effectors that further transmit the signal within the cell. Inositol phosphates are a group of mono- to poly-phosphorylated inositols, and include inositol monophosphate (IP), inositol trisphosphate (IP3), inositol pentakisphosphate (IP5) and inositol hexaphosphate (IP6). |
EDN1, EDN2, HRH1, ITPR2, ITPR3, INPP5A, ITPR1 |
GO:0048017 | BP | inositol lipid-mediated signaling | A series of molecular signals in which a cell uses an inositol-containing lipid to convert a signal into a response. Inositol lipids include the phosphoinositides (phosphatidylinositol and its phosphorylated derivatives), ceramides containing inositol, and inositol glycolipids. |
PLD1 |
GO:0048018 | MF | receptor agonist activity | Interacts with receptors such that the proportion of receptors in the active form is increased. |
GREM1, WNT2, VEGFA, WNT5A, WNT3, GAS6 |
GO:0048019 | MF | receptor antagonist activity | Interacts with receptors to reduce the action of another ligand, the agonist. |
DKK1, LRPAP1, ADH7, AGTR2, ESR2 |
GO:0048020 | MF | CCR chemokine receptor binding | Interacting selectively and non-covalently with a CCR chemokine receptor. |
CCL4, CCL20, CCL8 |
GO:0048022 | BP | negative regulation of melanin biosynthetic process | Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of melanin. |
WNT5A |
GO:0048023 | BP | positive regulation of melanin biosynthetic process | Any process that activates or increases the rate or extent of the chemical reactions and pathways resulting in the formation of melanin. |
ZEB2 |
GO:0048024 | BP | regulation of mRNA splicing, via spliceosome | Any process that modulates the frequency, rate or extent of mRNA splicing via a spliceosomal mechanism. |
SRSF10, SON, TIA1, SRPK2, JMJD6, YTHDC1, SRPK1, CWC22 |
GO:0048025 | BP | negative regulation of mRNA splicing, via spliceosome | Any process that stops, prevents or reduces the rate or extent of mRNA splicing via a spliceosomal mechanism. |
SAP18, SRSF10, HNRNPA2B1, PTBP1, RBMX, TRA2B, C1QBP, SRSF9, SRSF6, RNPS1 |
GO:0048026 | BP | positive regulation of mRNA splicing, via spliceosome | Any process that activates or increases the rate or extent of mRNA splicing via a spliceosomal mechanism. |
RBMX, TRA2B, DAZAP1, PRPF19, THRAP3 |
GO:0048027 | MF | mRNA 5'-UTR binding | Interacting selectively and non-covalently with the 5' untranslated region of an mRNA molecule. |
IGF2BP3, DDX3X, RPS14, FMR1, LARP1, IGF2BP2 |
GO:0048029 | MF | monosaccharide binding | Interacting selectively and non-covalently with any monosaccharide. Monosaccharides are the simplest carbohydrates; they are polyhydroxy aldehydes H[CH(OH)]nC(=O)H or polyhydroxy ketones H[CHOH]nC(=O)[CHOH]mH with three or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides. |
GPI, FBP1, TALDO1 |
GO:0048037 | MF | cofactor binding | Interacting selectively and non-covalently with a cofactor, a substance that is required for the activity of an enzyme or other protein. Cofactors may be inorganic, such as the metal atoms zinc, iron, and copper in certain forms, or organic, in which case they are referred to as coenzymes. Cofactors may either be bound tightly to active sites or bind loosely with the substrate. |
TYMS, ASNS, LMO2, TKT, SUCLG1, ME3 |
GO:0048038 | MF | quinone binding | Interacting selectively and non-covalently with a quinone, any member of a class of diketones derivable from aromatic compounds by conversion of two CH groups into CO groups with any necessary rearrangement of double bonds. |
AOC2, NDUFS2, ETFDH, AOC3, HHIP, VKORC1 |
GO:0048039 | MF | ubiquinone binding | Interacting selectively and non-covalently with ubiquinone, a quinone derivative with a tail of isoprene units. |
SDHB, DHODH, ETFDH |
GO:0048040 | MF | UDP-glucuronate decarboxylase activity | Catalysis of the reaction: H(+) + UDP-alpha-D-glucuronate = CO(2) + UDP-alpha-D-xylose. |
UXS1 |
GO:0048041 | BP | focal adhesion assembly | The aggregation and bonding together of a set of components to form a focal adhesion, a complex of intracellular signaling and structural proteins that provides a structural link between the internal actin cytoskeleton and the ECM, and also function as a locus of signal transduction activity. |
RHOD, ARHGAP6, BCL2, ACTN1, ITGA2, ACTN2, ARHGEF7, CTTN, PTPRK, TRIP6, AJUBA, DLC1, SORBS1, TAOK2 |
GO:0048048 | BP | embryonic eye morphogenesis | The process occurring in the embryo by which the anatomical structures of the post-embryonic eye are generated and organized. |
AXIN1, FBN1, FBN2, ALDH1A3, MFAP2, FOXL2, EFEMP1 |
GO:0048050 | BP | post-embryonic eye morphogenesis | The process, occurring after embryonic development, by which the anatomical structures of the eye are generated and organized. The eye is the organ of sight. |
FBN1, MFAP2, EFEMP1 |
GO:0048066 | BP | developmental pigmentation | The developmental process that results in the deposition of coloring matter in an organism, tissue or cell. |
BCL2L11, ZEB2, GNA11, PMEL, GNAQ, SLC45A2 |
GO:0048070 | BP | regulation of developmental pigmentation | Any process that modulates the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism. |
BCL2L11, KIT |
GO:0048075 | BP | positive regulation of eye pigmentation | Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in the eye of an organism. |
HPS4 |
GO:0048087 | BP | positive regulation of developmental pigmentation | Any process that increases the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism. |
BAX |
GO:0048096 | BP | chromatin-mediated maintenance of transcription | Maintenance of transcription by remodelling of chromatin into an 'open configuration'. Once established, this regulation is mitotically stable and is maintained over many cell divisions. It is also heritable. |
ARID1A, CHEK1, CTNNB1, ELOF1, ARID1B, SMARCD1, BAZ1B, KMT2B |
GO:0048102 | BP | autophagic cell death | A form of programmed cell death that is accompanied by the formation of autophagosomes. Autophagic cell death is characterized by lack of chromatin condensation and massive vacuolization of the cytoplasm, with little or no uptake by phagocytic cells. |
LAMP1, CDKN1B, BNIP3, TP53INP1, SH3GLB1 |
GO:0048103 | BP | somatic stem cell division | The self-renewing division of a somatic stem cell, a stem cell that can give rise to cell types of the body other than those of the germ-line. |
FZD7, KIT, NOTCH1, ZFP36L2, TGFB2 |
GO:0048133 | BP | male germ-line stem cell asymmetric division | The self-renewing division of a germline stem cell in the male gonad, to produce a daughter stem cell and a daughter germ cell, which will divide to form the male gametes. |
ETV5, ZBTB16 |
GO:0048143 | BP | astrocyte activation | A change in morphology and behavior of an astrocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. |
EGFR, MT1X |
GO:0048144 | BP | fibroblast proliferation | The multiplication or reproduction of fibroblast cells, resulting in the expansion of the fibroblast population. |
AGT |
GO:0048145 | BP | regulation of fibroblast proliferation | Any process that modulates the frequency, rate or extent of multiplication or reproduction of fibroblast cells. |
CREB1, CTNNB1 |
GO:0048146 | BP | positive regulation of fibroblast proliferation | Any process that activates or increases the frequency, rate or extent of multiplication or reproduction of fibroblast cells. |
EREG, NDUFS4, EGFR, AGT, MYC, PDGFB, TGFB1, FN1, ESR1, PDGFA, CD74, IGF1, JUN, S100A6, ANXA2, WNT2, PDGFRB, CDK4, MIF, CCNB1, FOSL2, PDGFRA, CCNA2, BTC, CDKN1A, WNT5A, PRKDC, CDK6, E2F1, GAS6, RNASEH2B, WAPL, CDC6, PDGFD, PDGFC, SPHK1, ZMIZ1 |
GO:0048147 | BP | negative regulation of fibroblast proliferation | Any process that stops, prevents, or reduces the frequency, rate or extent of multiplication or reproduction of fibroblast cells. |
NUPR1, MYC, FTH1, TP53, GSTP1, SKI, AGTR2, EMD, BAX, PMAIP1, MORC3, SFRP1, PAWR, DACH1 |
GO:0048148 | BP | behavioral response to cocaine | Any process that results in a change in the behavior of an organism as a result of a cocaine stimulus. |
DRD2, SNCA, ABAT, CDK5, SDK1, HOMER1 |
GO:0048149 | BP | behavioral response to ethanol | Any process that results in a change in the behavior of an organism as a result of an ethanol stimulus. |
DRD2, CHRNA7, USP46, EPS8, HDAC2 |
GO:0048156 | MF | tau protein binding | Interacting selectively and non-covalently with tau protein. tau is a microtubule-associated protein, implicated in Alzheimer's disease, Down Syndrome and ALS. |
APBB1, BIN1, APOE, S100B, HSP90AA1, SNCA, FKBP4, AATF, HDAC6 |
GO:0048160 | BP | primary follicle stage | The stage in oogenesis when a single layer of cuboidal follicle cells surrounds the oocyte. The oocyte nucleus is large. |
EREG |
GO:0048167 | BP | regulation of synaptic plasticity | A process that modulates synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers. |
NCAM1, ITPKA, HRH1, PSEN1, CDK5, YWHAH, MEF2C, EIF4EBP2, NFATC4, CNTN4, CPEB3, FGF14, SYNGAP1, PLK2, LZTS1 |
GO:0048168 | BP | regulation of neuronal synaptic plasticity | A process that modulates neuronal synaptic plasticity, the ability of neuronal synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers. |
APOE, S100B, EGR2, STAR, DBN1, NSMF, ARC |