GO:0046483

BP

heterocycle metabolic process

The chemical reactions and pathways involving heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings).

CYP2E1, CYP3A4, CYP2D6

GO:0046486

BP

glycerolipid metabolic process

The chemical reactions and pathways involving glycerolipids, any lipid with a glycerol backbone. Diacylglycerol and phosphatidate are key lipid intermediates of glycerolipid biosynthesis.

DGKZ

GO:0046487

BP

glyoxylate metabolic process

The chemical reactions and pathways involving glyoxylate, the anion of glyoxylic acid, HOC-COOH.

NDUFAB1, PDHA1, DLD, DLAT, PDHB, DBT, BCKDHA, AGXT, BCKDHB, GCSH, DLST, OGDH, GRHPR, LIPT1

GO:0046488

BP

phosphatidylinositol metabolic process

The chemical reactions and pathways involving phosphatidylinositol, any glycophospholipid in which a sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol.

SYNJ1, CSF1R, PDGFRB, DRD2, PLCB1

GO:0046490

BP

isopentenyl diphosphate metabolic process

The chemical reactions and pathways involving isopentenyl diphosphate, an isomer of dimethylallyl diphosphate and the key precursor of all isoprenoids.

IDI2

GO:0046491

BP

L-methylmalonyl-CoA metabolic process

The chemical reactions and pathways involving L-methylmalonyl-CoA, the L-enantiomer of 2-carboxypropanoyl-CoA. S-methylmalonyl-CoA is an intermediate in the beta oxidation of odd-numbered fatty acids in animals.

MCEE

GO:0046496

BP

nicotinamide nucleotide metabolic process

The chemical reactions and pathways involving nicotinamide nucleotides, any nucleotide that contains combined nicotinamide.

CARKD

GO:0046498

BP

S-adenosylhomocysteine metabolic process

The chemical reactions and pathways involving S-adenosylhomocysteine; the L-enantiomer is formed from S-adenosylmethionine and is a strong inhibitor of S-adenosylmethionine-mediated methylation reactions. It can be cleaved to form adenosine and homocysteine.

DNMT3B, PEMT

GO:0046499

BP

S-adenosylmethioninamine metabolic process

The chemical reactions and pathways involving S-adenosylmethioninamine, (5-deoxy-5-adenosyl)(3-aminopropyl) methylsulfonium salt.

DNMT3B

GO:0046500

BP

S-adenosylmethionine metabolic process

The chemical reactions and pathways involving S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism.

AMD1, MTHFR, PEMT

GO:0046511

BP

sphinganine biosynthetic process

The chemical reactions and pathways resulting in the formation of sphinganine, D-erythro-2-amino-1,3-octadecanediol.

SPTLC2

GO:0046512

BP

sphingosine biosynthetic process

The chemical reactions and pathways resulting in the formation of sphingosine (sphing-4-enine), trans-D-erytho-2-amino-octadec-4-ene-1,3-diol, a long chain amino diol sphingoid base that occurs in most sphingolipids in animal tissues.

SPTLC2, SPHK1

GO:0046513

BP

ceramide biosynthetic process

The chemical reactions and pathways resulting in the formation of ceramides, any N-acylated sphingoid.

SPTLC2, CERS6, SGMS1, CERS5, SGMS2, CERS4, SMPD4

GO:0046521

BP

sphingoid catabolic process

The chemical reactions and pathways resulting in the breakdown of sphingoids, any of a class of compounds comprising sphinganine and its homologues and stereoisomers, and derivatives of these compounds.

SPHK1

GO:0046526

MF

D-xylulose reductase activity

Catalysis of the reaction: NAD(+) + xylitol = D-xylulose + H(+) + NADH.

SORD

GO:0046527

MF

glucosyltransferase activity

Catalysis of the transfer of a glucosyl group to an acceptor molecule, typically another carbohydrate or a lipid.

KDELC1, KDELC2, ALG6

GO:0046533

BP

negative regulation of photoreceptor cell differentiation

Any process that stops, prevents, or reduces the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster.

NOTCH1, SOX9, SOX8

GO:0046538

MF

2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity

Catalysis of the reaction: 2-phospho-D-glycerate = 3-phospho-D-glycerate; this reaction requires the cofactor 2,3-bisphosphoglycerate.

BPGM, PGAM1

GO:0046539

MF

histamine N-methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine(1+) + histamine = N(tau)-methylhistamine + S-adenosyl-L-homocysteine + H(+).

HNMT

GO:0046540

CC

U4/U6 x U5 tri-snRNP complex

A ribonucleoprotein complex formed by the association of the U4/U6 and U5 small nuclear ribonucleoproteins.

PRPF3, PPIH, LSM8, SNRPB, SNU13, LSM3, LSM6, SNRPD2, SNRPN, PRPF31, ZMAT2, PRPF18, LSM2, LSM5

GO:0046541

BP

saliva secretion

The regulated release of saliva from the salivary glands. In man, the saliva is a turbid and slightly viscous fluid, generally of an alkaline reaction, and is secreted by the parotid, submaxillary, and sublingual glands. In the mouth the saliva is mixed with the secretion from the buccal glands. In man and many animals, saliva is an important digestive fluid on account of the presence of the peculiar enzyme, ptyalin.

CHRM3

GO:0046543

BP

development of secondary female sexual characteristics

The process whose specific outcome is the progression of the secondary female sexual characteristics over time, from their formation to the mature structures. In female humans, these include growth of axillary and pubic hair, breast development and menstrual periods. Their development occurs in response to sex hormone secretion.

STAT5B

GO:0046544

BP

development of secondary male sexual characteristics

The process whose specific outcome is the progression of the secondary male sexual characteristics over time, from their formation to the mature structures. In male humans, these include growth of axillary, chest, and pubic hair, voice changes, and testicular/penile enlargement. Development occurs in response to sex hormone secretion.

STAT5B

GO:0046545

BP

development of primary female sexual characteristics

The process whose specific outcome is the progression of the primary female sexual characteristics over time, from their formation to the mature structure. The primary female sexual characteristics are the ovaries, and they develop in response to sex hormone secretion.

ACVR1B, ADCYAP1R1, DACH1

GO:0046548

BP

retinal rod cell development

Development of a rod cell, one of the sensory cells in the eye that reacts to the presence of light. Rod cells contain the photopigment rhodopsin or porphyropsin and are responsible for vision in dim light.

NAGLU, NTRK2

GO:0046554

MF

malate dehydrogenase (NADP+) activity

Catalysis of the reaction: (S)-malate + NADP+ = oxaloacetate + NADPH + H+.

MDH2

GO:0046577

MF

long-chain-alcohol oxidase activity

Catalysis of the reaction: 2 long-chain alcohol + O2 = 2 long-chain aldehyde + 2 H2O.

ALDH3A2

GO:0046578

BP

regulation of Ras protein signal transduction

Any process that modulates the frequency, rate or extent of Ras protein signal transduction.

NUP62, FOXM1, SQSTM1

GO:0046579

BP

positive regulation of Ras protein signal transduction

Any process that activates or increases the frequency, rate or extent of Ras protein signal transduction.

NGF, NTRK1, IGF1, KITLG, NRG1, NOTCH2

GO:0046580

BP

negative regulation of Ras protein signal transduction

Any process that stops, prevents, or reduces the frequency, rate or extent of Ras protein signal transduction.

RASA4, SPRY2, SPRY1, MFN2, STAMBP, FBP1, TIMP2, RASA1, NUP62, TGFB2, PPP2CB, RAPGEF1, RASA3, RASA2, SYNGAP1, MAPKAP1, RABGEF1

GO:0046581

CC

intercellular canaliculus

An extremely narrow tubular channel located between adjacent cells. An instance of this is the secretory canaliculi occurring between adjacent parietal cells in the gastric mucosa of vertebrates.

DPP4, TJP1, MTDH

GO:0046587

BP

positive regulation of calcium-dependent cell-cell adhesion

Any process that activates or increases the frequency, rate or extent of calcium-dependent cell-cell adhesion.

KIFAP3

GO:0046596

BP

regulation of viral entry into host cell

Any process that modulates the frequency, rate or extent of the viral entry into the host cell.

TRIM25, TRIM62

GO:0046597

BP

negative regulation of viral entry into host cell

Any process that stops, prevents, or reduces the frequency, rate or extent of the entry of viral entry into a host cell.

SNX3, APCS, IFITM1, PTX3, IFITM3, TRIM26, TRIM25, TRIM8

GO:0046598

BP

positive regulation of viral entry into host cell

Any process that activates or increases the frequency, rate or extent of the introduction of viral entry into the host cell.

TRIM38, P4HB, LGALS1

GO:0046599

BP

regulation of centriole replication

Any process that modulates the frequency, rate or extent of the formation of a daughter centriole of an existing centriole.

NPM1, STIL, CENPJ, PLK2

GO:0046600

BP

negative regulation of centriole replication

Any process that stops, prevents, or reduces the frequency, rate or extent of centriole replication.

TRIM37, BRCA1, MDM1

GO:0046601

BP

positive regulation of centriole replication

Any process that activates or increases the frequency, rate or extent of centriole replication.

PLK4

GO:0046602

BP

regulation of mitotic centrosome separation

Any process that modulates the frequency, rate or extent of the separation of duplicated centrosome components at the beginning of mitosis.

CHEK1, NEK2, KIF11

GO:0046604

BP

positive regulation of mitotic centrosome separation

Any process that activates or increases the frequency, rate or extent of centrosome separation.

RANBP1

GO:0046605

BP

regulation of centrosome cycle

Any process that modulates the frequency, rate or extent of the centrosome cycle, the processes of centrosome duplication and separation.

AURKA

GO:0046618

BP

drug export

The directed movement of a drug, a substance used in the diagnosis, treatment or prevention of a disease, out of a cell or organelle.

SLC22A18, SLC47A1

GO:0046619

BP

optic placode formation involved in camera-type eye formation

Establishment and formation of the optic placode, paired ectodermal placodes that become invaginated to form the embryonic lens vesicles.

FRS2, PROX1

GO:0046620

BP

regulation of organ growth

Any process that modulates the frequency, rate or extent of growth of an organ of an organism.

BCL2L11, LATS1, FOXC1, LATS2

GO:0046621

BP

negative regulation of organ growth

Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organ of an organism.

PTEN, PTK2, STK4, FXN, WWC2, WWC1, WWC3

GO:0046622

BP

positive regulation of organ growth

Any process that activates or increases the frequency, rate or extent of growth of an organ of an organism.

SASH3, YAP1

GO:0046625

MF

sphingolipid binding

Interacting selectively and non-covalently with sphingolipids, a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).

S1PR1

GO:0046626

BP

regulation of insulin receptor signaling pathway

Any process that modulates the frequency, rate or extent of insulin receptor signaling.

OGT, TSC2, SIK2, NUCKS1, BAIAP2L1

GO:0046627

BP

negative regulation of insulin receptor signaling pathway

Any process that stops, prevents, or reduces the frequency, rate or extent of insulin receptor signaling.

SOCS2, SOCS3, MSTN, SOCS1, IL1B, AHSG, PRKCB, PTPN2, ENPP1, IRS1, TSC2, RELA, PRKCQ, PRKCD, GRB10, KANK1, PID1, INPP5K, LMBRD1

GO:0046628

BP

positive regulation of insulin receptor signaling pathway

Any process that increases the frequency, rate or extent of insulin receptor signaling.

INS, IGF2, IRS1, LEP, SERPINA12, ADIPOR1, NR1H4, OSBPL8, NUCKS1

GO:0046629

BP

gamma-delta T cell activation

The change in morphology and behavior of a gamma-delta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.

CXADR, MICB, MICA

GO:0046631

BP

alpha-beta T cell activation

The change in morphology and behavior of an alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.

INS

GO:0046632

BP

alpha-beta T cell differentiation

The process in which a precursor cell type acquires the specialized features of an alpha-beta T cell. An alpha-beta T cell is a T cell that expresses an alpha-beta T cell receptor complex.

ANXA1, RPL22

GO:0046633

BP

alpha-beta T cell proliferation

The expansion of an alpha-beta T cell population by cell division.

DOCK2

GO:0046636

BP

negative regulation of alpha-beta T cell activation

Any process that stops, prevents, or reduces the frequency, rate or extent of alpha-beta T cell activation.

LILRB1

GO:0046638

BP

positive regulation of alpha-beta T cell differentiation

Any process that activates or increases the frequency, rate or extent of alpha-beta T cell differentiation.

PNP, ADA, GLI3, SYK, NKAP

GO:0046639

BP

negative regulation of alpha-beta T cell differentiation

Any process that stops, prevents, or reduces the frequency, rate or extent of alpha-beta T cell differentiation.

GLI3

GO:0046641

BP

positive regulation of alpha-beta T cell proliferation

Any process that activates or increases the frequency, rate or extent of alpha-beta T cell proliferation.

RIPK2, CD28, TNFSF4, SYK

GO:0046651

BP

lymphocyte proliferation

The expansion of a lymphocyte population by cell division.

HELLS

GO:0046653

BP

tetrahydrofolate metabolic process

The chemical reactions and pathways involving tetrahydrofolate, 5,6,7,8-tetrahydrofolic acid, a folate derivative bearing additional hydrogens on the pterin group.

DHFR, MTHFD2, SHMT1, MTHFS, MTHFD1L, PIPOX

GO:0046654

BP

tetrahydrofolate biosynthetic process

The chemical reactions and pathways resulting in the formation of tetrahydrofolate, 5,6,7,8-tetrahydrofolic acid, a folate derivative bearing additional hydrogens on the pterin group.

DHFR, GART

GO:0046655

BP

folic acid metabolic process

The chemical reactions and pathways involving folic acid, pteroylglutamic acid. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines.

ALDH1L1, DHFR, MTHFD1, MTHFD2, FOLR1, SHMT1, SLC19A1, MTHFR, MTHFS, ALDH1L2, MTHFD1L, SLC46A1, MTHFD2L

GO:0046657

BP

folic acid catabolic process

The chemical reactions and pathways resulting in the breakdown of folic acid, pteroylglutamic acid.

MTHFS

GO:0046658

CC

anchored component of plasma membrane

The component of the plasma membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group, that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.

MFI2, EFNA1, GAS1, HYAL2, RGMB, RTN4RL1, ULBP3, ULBP2, RHBG

GO:0046661

BP

male sex differentiation

The establishment of the sex of a male organism by physical differentiation.

FKBP4

GO:0046666

BP

retinal cell programmed cell death

Programmed cell death that occurs in the developing retina.

BAX

GO:0046671

BP

negative regulation of retinal cell programmed cell death

Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death that occurs in the retina.

BCL2

GO:0046676

BP

negative regulation of insulin secretion

Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of insulin.

PARK2, PDE8B, INHBB, DRD2, PFKL, IRS1, SREBF1, PTPN11, PPP3CA, HDAC1, KCNJ11, HADH, MIDN, BMP8A, SFRP1, GHSR, SYTL4, GHRL, STXBP5L

GO:0046677

BP

response to antibiotic

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms.

JAK2, TP53, CYP1A1, ALPL, IL6, HSP90AA1, CCL2, ADRB3, JAK1, ID1, SLC1A3, UQCRFS1, CASP9, PPP2CB, MDM2, HYAL2, CASP8, AOC3, RSRC1

GO:0046680

BP

response to DDT

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a DDT stimulus. DDT, dichlorodiphenyltrichloroethane, is a chlorinated hydrocarbon pesticide moderately toxic to humans and other animals.

CCNB1

GO:0046683

BP

response to organophosphorus

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organophosphorus stimulus. Organophosphorus is a compound containing phosphorus bound to an organic molecule; several organophosphorus compounds are used as insecticides, and they are highly toxic cholinesterase inhibitors.

TYMS, RFC3, AKR1C1

GO:0046684

BP

response to pyrethroid

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pyrethroid stimulus. Pyrethroids are a group of growth regulators, analogous to insect juvenile hormones, that interfere with the development of insect larvae and are used in the control of insects that are harmful in the adult stage.

TH

GO:0046685

BP

response to arsenic-containing substance

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenic stimulus from compounds containing arsenic, including arsenates, arsenites, and arsenides.

TNFRSF11B, CYP1A1, ALAD, CPOX, SERPINF1, CDKN1A, GCLC, PTEN, RBM4

GO:0046686

BP

response to cadmium ion

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.

NPC1, CYB5A, PTH, PRNP, CDK1, GPI, SPARC, PCNA, ALAD, DTYMK, NUDT1, MAPK9, CDKN1B, GCLC, B2M, SORD, MTF1

GO:0046688

BP

response to copper ion

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus.

IL1A, ICAM1, CDK1, SOD3, PAM, ATP5D, SORD, S100A13, LOXL2

GO:0046689

BP

response to mercury ion

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mercury ion stimulus.

AQP9, ALAD, BSG

GO:0046690

BP

response to tellurium ion

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tellurium ion stimulus.

HMGCS1

GO:0046696

CC

lipopolysaccharide receptor complex

A multiprotein complex that consists of at least three proteins, CD14, TLR4, and MD-2, each of which is glycosylated and which functions as a lipopolysaccharide (LPS) receptor that primes the innate immune response against bacterial pathogens.

TLR4, BCL10, CD14, HSPD1

GO:0046697

BP

decidualization

The cellular and vascular changes occurring in the endometrium of the pregnant uterus just after the onset of blastocyst implantation. This process involves the proliferation and differentiation of the fibroblast-like endometrial stromal cells into large, polyploid decidual cells that eventually form the maternal component of the placenta.

CYP27B1, STC2, CTSB, SPP1, VDR, LIF, JUNB, EPOR, PTGS2, BSG, STC1, PPARD, PTGIS, GHSR, GHRL

GO:0046703

MF

natural killer cell lectin-like receptor binding

Interacting selectively and non-covalently with a lectin-like natural killer cell receptor.

HLA-E, MICB, MICA, ULBP3, ULBP2

GO:0046709

BP

IDP catabolic process

The chemical reactions and pathways resulting in the breakdown of IDP, inosine 5'-diphosphate.

NUDT16, NUDT9

GO:0046710

BP

GDP metabolic process

The chemical reactions and pathways involving GDP, guanosine 5'-diphosphate.

CASK, DLG4, MPP1, DLG1, TJP2

GO:0046711

BP

GDP biosynthetic process

The chemical reactions and pathways resulting in the formation of GDP, guanosine 5'-diphosphate.

GUK1

GO:0046716

BP

muscle cell cellular homeostasis

The cellular homeostatic process that preserves a muscle cell in a stable functional or structural state.

MSTN, LARGE, ALDOA, IL6, GAA, DMD, LAMP2, CAPN3, MTM1, HIF1A, SGCZ

GO:0046717

BP

acid secretion

The controlled release of acid by a cell or a tissue.

DRD2

GO:0046718

BP

viral entry into host cell

The process that occurs after viral attachment by which a virus, or viral nucleic acid, breaches the plasma membrane or cell envelope and enters the host cell. The process ends when the viral nucleic acid is released into the host cell cytoplasm.

WWP2, KPNA3, NPC1, SIVA1, CLDN1, LDLR, GYPA, TFRC, ITGB3, ICAM1, ITGB1, ITGAV, CTSB, CD55, ITGA5, RPSA, HSPA1A, HSPA1B, LAMP1, NCAM1, IDE, PVR, CD46, ITGA2, CR1, ITGB5, MRC1, DPP4, SERPINB3, EPS15, NUP153, EFNB2, CD81, DYNLT1, CXADR, TYRO3, SLC20A2, HYAL2, DAG1, SELPLG, GAS6, NECTIN1, SLC1A5, SCARB1, ITCH, WWP1, CD209, ZNF639, F11R

GO:0046724

BP

oxalic acid secretion

The controlled release of oxalic acid, ethanedioic acid, by a cell or a tissue.

AGXT

GO:0046726

BP

positive regulation by virus of viral protein levels in host cell

Any process where the infecting virus increases the levels of viral proteins in a cell.

STAU1, HACD3

GO:0046732

BP

active induction of host immune response by virus

The intentional, virally-encoded stimulation of a host defense response to viral infection.

TGFB1

GO:0046745

BP

viral capsid secondary envelopment

The process in which a capsid acquires another membrane envelope, subsequent to acquiring an initial membrane envelope.

IST1

GO:0046755

BP

viral budding

A viral process by which enveloped viruses acquire a host-derived membrane enriched in viral proteins to form their external envelope. The process starts when nucleocapsids, assembled or in the process of being built, induce formation of a membrane curvature in the host plasma or organelle membrane and wrap up in the forming bud. The process ends when the bud is eventually pinched off by membrane scission to release the enveloped particle into the lumenal or extracellular space.

CHMP4B, VTA1

GO:0046777

BP

protein autophosphorylation

The phosphorylation by a protein of one or more of its own amino acid residues (cis-autophosphorylation), or residues on an identical protein (trans-autophosphorylation).

AURKA, MUSK, MAP3K13, DAPK3, JAK2, ULK1, ERN1, STK17B, EGFR, ERBB2, NTRK1, EIF2S1, INSR, CSF1R, LYN, IGF1R, PDGFRB, FGR, KIT, BCR, FGFR1, PDGFRA, PRKACA, MAK, FGFR2, NME2, CAD, AKT1, GRK5, FLT4, ACVR1B, MAPKAPK2, CLK2, GSK3B, IRAK1, PRKX, NEK2, DAPK1, EPHB4, EPHB1, EPHA4, SIK1, CDK5, TEK, PTK2, TYRO3, DDR1, STK4, PAK2, TRIM28, RIPK1, CAMK2D, MELK, PRKD1, ERBB4, STK11, NTRK2, AAK1, MLK4, MINK1, UHMK1, AURKB, SMG1, TRPM7, PASK, VRK1, MKNK1, WNK3, PRKD2, SIK2, TAOK3, WNK1, CLK4, MKNK2, NEK6, ATP13A2, CDK12, EIF2AK4, NLK, TNIK, IRAK3, STK24

GO:0046778

BP

modification by virus of host mRNA processing

Any viral process that interferes with the processing of mRNA in the host cell.

PABPN1

GO:0046784

BP

viral mRNA export from host cell nucleus

The directed movement of intronless viral mRNA from the host nucleus to the cytoplasm for translation.

THOC7, ALYREF, THOC2, THOC3

GO:0046785

BP

microtubule polymerization

The addition of tubulin heterodimers to one or both ends of a microtubule.

ZNF207, TPPP, FGF13, TRPV4, CENPJ, FBXO5, HDGFRP3

GO:0046789

MF

host cell surface receptor binding

Interacting selectively and non-covalently with a receptor on the host cell surface.

INHBB

GO:0046790

MF

virion binding

Interacting selectively and non-covalently with a virion, either by binding to components of the capsid or the viral envelope.

APCS, HSP90B1, PTX3, PPIA, NECTIN1, HIPK2, CD209

GO:0046811

MF

histone deacetylase inhibitor activity

Stops, prevents or reduces the activity of histone deacetylase, which catalyzes of the removal of acetyl groups from histones, proteins complexed to DNA in chromatin and chromosomes.

SKI

GO:0046813

BP

receptor-mediated virion attachment to host cell

The process by which a virion attaches to a host cell by binding to a receptor on the host cell surface.

ICAM1, CD81, GAS6

GO:0046817

MF

chemokine receptor antagonist activity

Interacts with chemokine receptors to reduce the action of a chemokine.

CCL5