| GO ID | Ontology | GO Term | Term Definition |
Proteins |
GO:0040015 | BP | negative regulation of multicellular organism growth | Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organism to reach its usual body size. |
STC2, ADRB2, ADRB1, ADRB3, PTCH1, FXN, BBS2 |
GO:0040016 | BP | embryonic cleavage | The first few specialized divisions of an activated animal egg. |
TOP1, TOP2A, ERCC2, PIK3CB, CUL3, TPRA1, AATF |
GO:0040017 | BP | positive regulation of locomotion | Any process that activates or increases the frequency, rate or extent of locomotion of a cell or organism. |
BVES |
GO:0040018 | BP | positive regulation of multicellular organism growth | Any process that activates or increases the frequency, rate or extent of growth of an organism to reach its usual body size. |
GH1, GHRH, BCL2, GHR, DRD2, EZR, CREB1, PPIB, STAT5B, HSF1, PLS1, NIPBL, GHSR, BBS2, SPTBN4, GPAM, MKKS, CHD7, GHRL |
GO:0040019 | BP | positive regulation of embryonic development | Any process that activates or increases the frequency, rate or extent of embryonic development. |
OTX2, AMOT, PLCB1 |
GO:0040020 | BP | regulation of meiotic nuclear division | Any process that modulates the frequency, rate or extent of meiosis, the process in which the nucleus of a diploid cell divides twice forming four haploid cells, one or more of which usually function as gametes. |
CALR, CDC20, PDE3A, FZR1 |
GO:0040023 | BP | establishment of nucleus localization | The directed movement of the nucleus to a specific location within a cell. |
PTK2 |
GO:0040029 | BP | regulation of gene expression, epigenetic | Any process that modulates the frequency, rate or extent of gene expression; the process is mitotically or meiotically heritable, or is stably self-propagated in the cytoplasm of a resting cell, and does not entail a change in DNA sequence. |
H2AFY, GPX1, HDAC4, MTA1, TDG, IFI16, GLMN, ZNF335, HDAC6, HDAC5, KLF2 |
GO:0040032 | BP | post-embryonic body morphogenesis | The process in which the anatomical structures of the post-embryonic soma are generated and organized. |
GNAS, GNAS |
GO:0040036 | BP | regulation of fibroblast growth factor receptor signaling pathway | Any process that modulates the frequency, rate or extent of fibroblast growth factor receptor signaling pathway activity. |
FGFR2, OTX2, RUNX2, DUSP6, SULF1, FAM20C, HHIP |
GO:0040037 | BP | negative regulation of fibroblast growth factor receptor signaling pathway | Any process that stops, prevents, or reduces the frequency, rate or extent of fibroblast growth factor receptor signaling pathway activity. |
SPRY2, SPRY1, THBS1, GPC1, WNT5A, SHISA2, SULF2, SULF1 |
GO:0040038 | BP | polar body extrusion after meiotic divisions | The cell cycle process in which two small cells are generated, as byproducts destined to degenerate, as a result of the first and second meiotic divisions of a primary oocyte during its development to a mature ovum. One polar body is formed in the first division of meiosis and the other in the second division; at each division, the cytoplasm divides unequally, so that the polar body is of much smaller size than the developing oocyte. At the second division in which a polar body is formed, the polar body and the developing oocyte each contain a haploid set of chromosomes. |
FMN2 |
GO:0042008 | MF | interleukin-18 receptor activity | Combining with interleukin-18 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. |
IL18R1 |
GO:0042015 | MF | interleukin-20 binding | Interacting selectively and non-covalently with interleukin-20. |
IFNGR1, IFNAR2 |
GO:0042019 | MF | interleukin-23 binding | Interacting selectively and non-covalently with interleukin-23. |
IL12RB1 |
GO:0042020 | MF | interleukin-23 receptor activity | Combining with interleukin-23 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. |
IL12RB1 |
GO:0042022 | CC | interleukin-12 receptor complex | A protein complex that binds interleukin-12 and that consists of, at a minimum, a dimeric interleukin and its two receptor subunits as well as optional additional kinase subunits. |
IL12RB1 |
GO:0042023 | BP | DNA endoreduplication | Regulated re-replication of DNA within a single cell cycle, resulting in an increased cell ploidy. An example of this process occurs in the synthesis of Drosophila salivary gland cell polytene chromosomes. |
ZPR1 |
GO:0042026 | BP | protein refolding | The process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones. |
DNAJA2, HSP90AA1, HSPA1A, HSPA1B, HSPD1, HSPA6, DNAJB2, HSPA1L, B2M, DNAJA4 |
GO:0042030 | MF | ATPase inhibitor activity | Stops, prevents or reduces the activity of any enzyme that catalyzes the hydrolysis of ATP to ADP and orthophosphate. |
PLN |
GO:0042033 | BP | chemokine biosynthetic process | The chemical reactions and pathways resulting in the formation of chemokines, any member of a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria. |
IL18 |
GO:0042035 | BP | regulation of cytokine biosynthetic process | Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cytokines. |
IGF2BP3, PRG2, ZNF287, IGF2BP2 |
GO:0042036 | BP | negative regulation of cytokine biosynthetic process | Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cytokines. |
TIA1, RNF128, FOXP3 |
GO:0042043 | MF | neurexin family protein binding | Interacting selectively and non-covalently with neurexins, synaptic cell surface proteins related to latrotoxin receptor, laminin and agrin. Neurexins act as cell recognition molecules at nerve terminals. |
SDCBP, CASK, CPE, NLGN4X, NLGN1, SYTL4, SYTL2 |
GO:0042045 | BP | epithelial fluid transport | The directed movement of fluid across epithelia. |
AHCYL1, EDN1, ITPR1 |
GO:0042048 | BP | olfactory behavior | The behavior of an organism in response to an odor. |
UBR3, CHD7 |
GO:0042053 | BP | regulation of dopamine metabolic process | Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving dopamine. |
PARK2, NR4A2, PNKD |
GO:0042054 | MF | histone methyltransferase activity | Catalysis of the reaction: S-adenosyl-L-methionine + histone = S-adenosyl-L-homocysteine + methyl-histone. Histone methylation generally occurs on either an arginine or lysine residue. |
SUZ12, EZH2, CARM1, PRMT6, PRMT1 |
GO:0042056 | MF | chemoattractant activity | Providing the environmental signal that initiates the directed movement of a motile cell or organism towards a higher concentration of that signal. |
PDGFB, FGF2, HMGB1, SAA1, SAA2, CCL3, BMP4, CCL5, SCG2, MIF, HGF, VEGFA, LGALS3, FGF7, HMGB2, CXCL12, VEGFC, ALKBH1 |
GO:0042058 | BP | regulation of epidermal growth factor receptor signaling pathway | Any process that modulates the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity. |
CDH13, RHBDF1, MVB12A |
GO:0042059 | BP | negative regulation of epidermal growth factor receptor signaling pathway | Any process that stops, prevents, or reduces the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity. |
SPRY2, SPRY1, STAM2, AP2A2, EGFR, CLTA, UBC, PTPN2, NUP62, EPS15, AP2S1, CDC42, RPS27A, UBA52, GRB2, AP2B1, PTPRJ, ARHGEF7, STAM, AP2M1, SH3GL2, RNF126 |
GO:0042060 | BP | wound healing | The series of events that restore integrity to a damaged tissue, following an injury. |
EREG, EGFR, TIMP1, INS, COL3A1, FN1, RAF1, PDGFA, ERBB2, ITGB3, S100A8, DCN, FGF2, SPARC, TPM1, PDGFRB, GLI3, DSP, ALOX15, PDGFRA, SDC1, ERBB3, TNC, LOX, SDC4, TGFBR1, TGFBR2, WNT5A, ELK3, SLC11A1, TGFB2, CCL20, SMAD3, NRG1, PPARD, PPARA, PTK7, ITGA9, C6orf89, SCARB1, DCBLD2, MAP3K5, CORO1B, WNT5B, EPB41L4B, FGFR1OP2, SPRR3, MACF1 |
GO:0042063 | BP | gliogenesis | The process that results in the generation of glial cells. This includes the production of glial progenitors and their differentiation into mature glia. |
ANXA1, CDK6 |
GO:0042073 | BP | intraciliary transport | The bidirectional movement of large protein complexes along microtubules within a cilium, mediated by motor proteins. |
SSNA1, BBS12, RPGR, IFT27, IFT46, HSPB11 |
GO:0042074 | BP | cell migration involved in gastrulation | The migration of individual cells within the blastocyst to help establish the multi-layered body plan of the organism (gastrulation). For example, the migration of cells from the surface to the interior of the embryo (ingression). |
LRP5, AMOT, SOX17 |
GO:0042088 | BP | T-helper 1 type immune response | An immune response which is associated with resistance to intracellular bacteria, fungi, and protozoa, and pathological conditions such as arthritis, and which is typically orchestrated by the production of particular cytokines by T-helper 1 cells, most notably interferon-gamma, IL-2, and lymphotoxin. |
TLR4, BCL3, IL18 |
GO:0042089 | BP | cytokine biosynthetic process | The chemical reactions and pathways resulting in the formation of cytokines, any of a group of proteins that function to control the survival, growth and differentiation of tissues and cells, and which have autocrine and paracrine activity. |
CD28, PCSK5 |
GO:0042092 | BP | type 2 immune response | An immune response which is associated with resistance to extracellular organisms such as helminths and pathological conditions such as allergy, which is orchestrated by the production of particular cytokines, most notably IL-4, IL-5, IL-10, and IL-13, by any of a variety of cell types including T-helper 2 cells, eosinophils, basophils, mast cells, and nuocytes, resulting in enhanced production of certain antibody isotypes and other effects. |
IL33, IL10, BCL6, IL18 |
GO:0042093 | BP | T-helper cell differentiation | The process in which a relatively unspecialized thymocyte acquires specialized features of a T-helper cell. |
PTGER4 |
GO:0042094 | BP | interleukin-2 biosynthetic process | The chemical reactions and pathways resulting in the formation of interleukin-2. |
IL18, PAWR, IL1RAP |
GO:0042095 | BP | interferon-gamma biosynthetic process | The chemical reactions and pathways resulting in the formation of interferon-gamma. Interferon gamma is the only member of the type II interferon found so far. |
IL18 |
GO:0042098 | BP | T cell proliferation | The expansion of a T cell population by cell division. Follows T cell activation. |
RIPK2, CTPS1, TNFSF4, CCND3, PSMB10, CD151, PIK3CG, RC3H2 |
GO:0042100 | BP | B cell proliferation | The expansion of a B cell population by cell division. Follows B cell activation. |
IFNA1 , IFNA16, PTPRC, BCL2, HSPD1, IL7R, CTPS1, IL10, CD40LG, PRKCD, MEF2C, SHB, IFNE |
GO:0042101 | CC | T cell receptor complex | A protein complex that contains a disulfide-linked heterodimer of T cell receptor (TCR) chains, which are members of the immunoglobulin superfamily, and mediates antigen recognition, ultimately resulting in T cell activation. The TCR heterodimer is associated with the CD3 complex, which consists of the nonpolymorphic polypeptides gamma, delta, epsilon, zeta, and, in some cases, eta (an RNA splice variant of zeta) or Fc epsilon chains. |
BCL10, CD4, CD6, SYK, ALCAM |
GO:0042102 | BP | positive regulation of T cell proliferation | Any process that activates or increases the rate or extent of T cell proliferation. |
SASH3, PNP, IL1B, CD4, TFRC, ANXA1, IL6, PTPRC, CD28, CCL5, CD46, CD1D, VCAM1, HLA-DPA1, ZP3, TNFSF4, HLA-DMB, IL12A, CD40LG, CD6, CORO1A, IL6ST, LEP, DHPS, JAK3, PRKCQ, HES1, CD276, VTCN1, TNFSF13B |
GO:0042104 | BP | positive regulation of activated T cell proliferation | Any process that activates or increases the rate or extent of activated T cell proliferation. |
IGF2, IGF1, HMGB1, IGFBP2, TNFSF4, CD24, IL12RB1, STAT5B, FADD, IL18, GPAM, PYCARD |
GO:0042108 | BP | positive regulation of cytokine biosynthetic process | Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cytokines. |
EREG |
GO:0042109 | BP | lymphotoxin A biosynthetic process | The chemical reactions and pathways resulting in the formation of the cytokine lymphotoxin A. |
BCL10 |
GO:0042110 | BP | T cell activation | The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. |
PIK3CD, RAB29, ADA, FYN, HSPD1, PRLR, IFNAR1, DPP4, CHRNA7, DDOST, PIK3CG, SMAD3, PPP3CA, DLG1, CASP8, CD276, CLEC7A, FOXP3, AZI2, KIF13B |
GO:0042113 | BP | B cell activation | The change in morphology and behavior of a mature or immature B cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. |
PIK3CD, SKAP2, PRKCB, HSPD1, CHRNA7, HDAC4, IGBP1, BST2, CASP8, HDAC9, HDAC5 |
GO:0042116 | BP | macrophage activation | A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. |
TLR4, EDN2, SLC11A1, SLC7A2, TLR1, JMJD6, CRTC3, FOXP1, CD93 |
GO:0042117 | BP | monocyte activation | The change in morphology and behavior of a monocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. |
ADAM10, MT1G, HYAL2, ADAM9, FOXP1 |
GO:0042118 | BP | endothelial cell activation | The change in morphology and behavior of an endothelial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. |
TGFBR1, SMAD4, BMPER, APOLD1, P2RX4, FOXP1 |
GO:0042119 | BP | neutrophil activation | The change in morphology and behavior of a neutrophil resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. |
CXCL8, CCL5, CXCR2, F2RL1, PRKCD, KMT2E |
GO:0042126 | BP | nitrate metabolic process | The chemical reactions and pathways involving nitrates, inorganic or organic salts and esters of nitric acid. |
MARC1 |
GO:0042127 | BP | regulation of cell proliferation | Any process that modulates the frequency, rate or extent of cell proliferation. |
TNFRSF11B, NR5A2, CHEK1, TNFRSF10C, MAFG, RBFOX2, NUAK1, JAK2, LGR5, TNFRSF21, PLAU, AGT, PPBP, PF4, INHA, JUN, FYN, NGFR, FGR, KIT, ESRRA, JUP, JUNB, JUND, TAL1, CXCL2, TNFRSF1B, SAT1, ERBB3, PTGS1, JAK1, IL4R, FAS, DNMT1, CD27, AGTR1, RPA3, LTBR, TGFBR2, BRCA1, BCL6, CSK, EPS15, ABL2, PTGER2, PLA2G4A, SOX9, PLCD1, BID, JAG1, CXCL6, XIAP, HHEX, PTK2, TNK2, PKD2, BMPR2, EZH2, CCDC88A, STYK1, FA2H, EID2, ARHGEF2, TNFRSF25, SGK3, CIB1, RNF126, GNL3, CDCA7, TXNIP, EGLN3, CHST11, DUSP22, PDS5B, DHCR7, GHRL, CFDP1, TCFL5 |
GO:0042128 | BP | nitrate assimilation | The nitrogen metabolic process that encompasses the uptake of nitrate from the environment and reduction to ammonia, and results in the incorporation of nitrogen derived from nitrate into cellular substances. |
SUOX |
GO:0042129 | BP | regulation of T cell proliferation | Any process that modulates the frequency, rate or extent of T cell proliferation. |
RAC2, LGALS3, CTNNB1, SOS1, CD209 |
GO:0042130 | BP | negative regulation of T cell proliferation | Any process that stops, prevents or reduces the rate or extent of T cell proliferation. |
TNFRSF21, PDE5A, TGFB1, CEBPB, HLA-G, IL10, DLG1, CD276, LILRB1, GLMN, PELI1, PAWR, NDFIP1, FOXP3, MARCH7, VSIG4, MAD1L1 |
GO:0042131 | MF | thiamine phosphate phosphatase activity | Catalysis of the reaction: thiamine phosphate + H2O = thiamine + phosphate. |
ACPP |
GO:0042132 | MF | fructose 1,6-bisphosphate 1-phosphatase activity | Catalysis of the reaction: D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate. |
FBP2, FBP1 |
GO:0042133 | BP | neurotransmitter metabolic process | The chemical reactions and pathways involving neurotransmitters, any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. |
MAOA, CLN3 |
GO:0042134 | MF | rRNA primary transcript binding | Interacting selectively and non-covalently with an unprocessed ribosomal RNA transcript. |
PTRF |
GO:0042135 | BP | neurotransmitter catabolic process | The chemical reactions and pathways resulting in the breakdown of any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. |
MAOA, COMT, MAOB, ABAT |
GO:0042136 | BP | neurotransmitter biosynthetic process | The chemical reactions and pathways resulting in the formation of any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. |
TH, ALDH9A1, DAGLB |
GO:0042137 | BP | sequestering of neurotransmitter | The process of binding or confining a neurotransmitter such that it is separated from other components of a biological system. |
SLC18A2 |
GO:0042138 | BP | meiotic DNA double-strand break formation | The cell cycle process in which double-strand breaks are generated at defined hotspots throughout the genome during meiosis I. This results in the initiation of meiotic recombination. |
TOP6BL |
GO:0042147 | BP | retrograde transport, endosome to Golgi | The directed movement of membrane-bounded vesicles from endosomes back to the trans-Golgi network where they are recycled for further rounds of transport. |
WASH1, GOSR2, RAB29, STX6, SPAG9, VPS26A, CLN5, RHOBTB3, RAB7A, RAB9A, AP1S1, SNX1, DCTN1, VAMP3, DENND5A, ERC1, GBF1, TBC1D5, VPS35, RNF126, RAB6B, BET1L, ANKFY1, VPS29, VTI1B, SNX6, PIKFYVE, SNX5 |
GO:0042148 | BP | strand invasion | The process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules. |
RAD51C, RAD51D, RAD51 |
GO:0042149 | BP | cellular response to glucose starvation | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of glucose. |
TP53, ASNS, BCL2, HSPA5, SLC2A1, XBP1, ATF4, PRKAA2, PMAIP1, IFI16, UPP1, CPEB4, PIK3C3, PIK3R4, MYBBP1A, IMPACT, SH3GLB1, TBL2 |
GO:0042157 | BP | lipoprotein metabolic process | The chemical reactions and pathways involving any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids. |
ABCA1, APOA1, APOE, APOA2, APOC1, APOC3, ALB, APOB, LPL, BMP1, PRKACA, SDC1, HSPG2, PPARA, APOA5, PCSK9, SCARB1, APOLD1, APOL2 |
GO:0042158 | BP | lipoprotein biosynthetic process | The chemical reactions and pathways resulting in the formation of any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids. |
APOA1, APOE, APOA2, APOB, P4HB |
GO:0042159 | BP | lipoprotein catabolic process | The chemical reactions and pathways resulting in the breakdown of any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids. |
LDLR, APOE, APOB |
GO:0042162 | MF | telomeric DNA binding | Interacting selectively and non-covalently with a telomere, a specific structure at the end of a linear chromosome required for the integrity and maintenance of the end. |
KDM1A, XRCC5, TERF1, HNRNPD, ACD, SMG1, UPF3A, PIF1, OBFC1, UPF2, POT1, SMG5 |
GO:0042163 | MF | interleukin-12 beta subunit binding | Interacting selectively and non-covalently with the beta subunit of interleukin-12. |
IL12A |
GO:0042165 | MF | neurotransmitter binding | Interacting selectively and non-covalently with a neurotransmitter, any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell. |
NIPSNAP1 |
GO:0042166 | MF | acetylcholine binding | Interacting selectively and non-covalently with acetylcholine, an acetic acid ester of the organic base choline that functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions. |
CHRNB1, CHRM3, CHRNA5, CHRNA7 |
GO:0042167 | BP | heme catabolic process | The chemical reactions and pathways resulting in the breakdown of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring. |
AMBP, HMOX1, BLVRB |
GO:0042168 | BP | heme metabolic process | The chemical reactions and pathways involving heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring. |
BDH2 |
GO:0042169 | MF | SH2 domain binding | Interacting selectively and non-covalently with a SH2 domain (Src homology 2) of a protein, a protein domain of about 100 amino-acid residues and belonging to the alpha + beta domain class. |
SH3PXD2B, SYNGR3, JAK2, IRS1, NUP62, RACK1, PTK2, ARHGAP5, SQSTM1, DAG1, AFAP1L2, SHCBP1, LILRB1, DLC1, TRPV4, PAG1, NLK |
GO:0042171 | MF | lysophosphatidic acid acyltransferase activity | Catalysis of the transfer of acyl groups from an acyl-CoA to lysophosphatidic acid to form phosphatidic acid. |
ABHD5 |
GO:0042176 | BP | regulation of protein catabolic process | Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds. |
XPO1, FURIN, ODC1, CDC42, MDM2, NEDD4L, FAM83D, FAF1 |
GO:0042177 | BP | negative regulation of protein catabolic process | Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds. |
AZIN1, MDM4, SNX3, EGFR, INS, FYN, SERPINE2, FLNA, PHB, SMAD3, NRG1, RELA, GRIN2A, MAD2L1, SIRT2, BANP, FMN2, SNX12, IRAK3 |
GO:0042178 | BP | xenobiotic catabolic process | The chemical reactions and pathways resulting in the breakdown of a xenobiotic compound, a compound foreign to living organisms. Used of chemical compounds, e.g. a xenobiotic chemical, such as a pesticide. |
GSTM1, GSTM3, GSTM2, ACSL1, GSTO1, GSTM4, CRYZ |
GO:0042180 | BP | cellular ketone metabolic process | The chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms, as carried out by individual cells. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups. |
CYP2B6, DHRS4 |
GO:0042182 | BP | ketone catabolic process | The chemical reactions and pathways resulting in the breakdown of ketones, a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups. |
OXCT1 |
GO:0042197 | BP | halogenated hydrocarbon metabolic process | The chemical reactions and pathways involving halogenated hydrocarbons, any hydrocarbon with one or more halogen atoms attached to it. Halogens include fluorine, chlorine, bromine and iodine. |
CYP2E1 |
GO:0042214 | BP | terpene metabolic process | The chemical reactions and pathways involving terpenes, any of a large group of hydrocarbons that are made up of isoprene (C5H8) units which may be cyclic, acyclic or multicyclic, saturated or unsaturated, and may contain various functional groups. |
TH |
GO:0042219 | BP | cellular modified amino acid catabolic process | The chemical reactions and pathways resulting in the breakdown of compounds derived from amino acids, organic acids containing one or more amino substituents. |
GGACT |
GO:0042220 | BP | response to cocaine | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cocaine stimulus. Cocaine is a crystalline alkaloid obtained from the leaves of the coca plant. |
HSP90AA1, HSP90AB1, HSPD1, DRD2, CNR1, SLC6A1, OXTR, HNMT, MDM2, TIAM1, DPYSL2, HDAC2, ADGRL3, DNMT3B, HDAC5 |
GO:0042226 | BP | interleukin-6 biosynthetic process | The chemical reactions and pathways resulting in the formation of interleukin-6. |
BCL10 |
GO:0042231 | BP | interleukin-13 biosynthetic process | The chemical reactions and pathways resulting in the formation of interleukin-13. |
IL18 |
GO:0042245 | BP | RNA repair | Any process that results in the repair of damaged RNA. |
ALKBH1, FTO |
GO:0042246 | BP | tissue regeneration | The regrowth of lost or destroyed tissues. |
APOD, IGFBP1, CCNB1, GAP43, NOTCH1, TM4SF4, APOA5, CPQ |
GO:0042253 | BP | granulocyte macrophage colony-stimulating factor biosynthetic process | The chemical reactions and pathways resulting in the formation of granulocyte macrophage colony-stimulating factor, cytokines that act in hemopoiesis by controlling the production, differentiation, and function of two related white cell populations, granulocytes and monocytes-macrophages. |
IL18 |
GO:0042254 | BP | ribosome biogenesis | A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits; includes transport to the sites of protein synthesis. |
GTPBP10, GNL1, RPL34, RPS18, BOP1, ZNF658, MINA, NAF1, MTG1, GNL3, MTG2, DDX31, GNL3L, AATF, RRN3, MRPL36 |
GO:0042255 | BP | ribosome assembly | The aggregation, arrangement and bonding together of the mature ribosome and of its subunits. |
NPM1, TSR1, NIP7 |
GO:0042256 | BP | mature ribosome assembly | The aggregation, arrangement and bonding together of the large and small ribosomal subunits into a functional ribosome. |
DDX3X, EIF6, C1QBP, SBDS |
GO:0042262 | BP | DNA protection | Any process in which DNA is protected from damage by, for example, oxidative stress. |
CBS, NUDT1, GLRX2, NUDT15 |
GO:0042267 | BP | natural killer cell mediated cytotoxicity | The directed killing of a target cell by a natural killer cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors. |
TUBB, CEBPG, TUBB4B, PRDX1, MICB, MICA, LYST, ULBP3, ULBP2 |