GO:0033630

BP

positive regulation of cell adhesion mediated by integrin

Any process that activates or increases the frequency, rate, or extent of cell adhesion mediated by integrin.

SYK, RAC3, TGFB2, ADAM9, IFT74, CIB1

GO:0033631

BP

cell-cell adhesion mediated by integrin

The attachment of one cell to another cell via an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits.

ITGB1, ITGA5, ADAM9

GO:0033632

BP

regulation of cell-cell adhesion mediated by integrin

Any process that modulates the frequency, rate, or extent of cell-cell adhesion mediated by integrin.

ADA, DPP4

GO:0033634

BP

positive regulation of cell-cell adhesion mediated by integrin

Any process that activates or increases the frequency, rate, or extent of cell-cell adhesion mediated by integrin.

CCL5, PIEZO1

GO:0033668

BP

negative regulation by symbiont of host apoptotic process

Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of programmed cell death in the host, where programmed cell death proceeds by apoptosis. The host is defined as the larger of the organisms involved in a symbiotic interaction.

SERPINB9

GO:0033673

BP

negative regulation of kinase activity

Any process that stops, prevents, or reduces the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.

MSTN, CSK, CDKN1B, CDKN1C, AJUBA, IRS2

GO:0033674

BP

positive regulation of kinase activity

Any process that activates or increases the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.

NBN, MRE11A, LMO4, DSTYK, PIFO, GCN1, RAD50

GO:0033676

MF

double-stranded DNA-dependent ATPase activity

Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction requires the presence of double-stranded DNA, and it drives another reaction.

ANXA1

GO:0033682

MF

ATP-dependent 5'-3' DNA/RNA helicase activity

Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of a DNA/RNA duplex in the direction 5' to 3'.

PIF1

GO:0033683

BP

nucleotide-excision repair, DNA incision

A process that results in the endonucleolytic cleavage of the damaged strand of DNA. The incision occurs at the junction of single-stranded DNA and double-stranded DNA that is formed when the DNA duplex is unwound.

ERCC1, PARP1, UBC, PCNA, ERCC2, XPA, POLD1, GTF2H1, RPA3, RFC4, RFC2, RFC5, RFC3, RBX1, RPS27A, UBA52, CUL4A, CUL4B, GTF2H2, POLD3, CHD1L, GTF2H4, ERCC4, POLD4, POLK, FAN1

GO:0033686

BP

positive regulation of luteinizing hormone secretion

Any process that activates or increases the frequency, rate or extent of the regulated release of luteinizing hormone.

LEP, FOXL2, SMAD4, KISS1

GO:0033687

BP

osteoblast proliferation

The multiplication or reproduction of osteoblasts, resulting in the expansion of an osteoblast cell population. An osteoblast is a bone-forming cell which secretes an extracellular matrix. Hydroxyapatite crystals are then deposited into the matrix to form bone.

JUNB

GO:0033688

BP

regulation of osteoblast proliferation

Any process that modulates the frequency, rate or extent of osteoblast proliferation.

NPR3, FGFR2, RHOA

GO:0033689

BP

negative regulation of osteoblast proliferation

Any process that stops, prevents or reduces the rate or extent of osteoblast proliferation.

GREM1, BCL2, SMAD3, SFRP1

GO:0033690

BP

positive regulation of osteoblast proliferation

Any process that activates or increases the rate or extent of osteoblast proliferation.

CYR61, LRP5, ITGAV, BMP2, SOX8, CTHRC1, HPSE

GO:0033691

MF

sialic acid binding

Interacting selectively and non-covalently with sialic acid, any of a variety of N- or O- substituted derivatives of neuraminic acid, a nine carbon monosaccharide. Sialic acids often occur in polysaccharides, glycoproteins, and glycolipids in animals and bacteria.

SELE, ADIPOQ, ST8SIA4

GO:0033692

BP

cellular polysaccharide biosynthetic process

The chemical reactions and pathways resulting in the formation of polysaccharides, polymers of many (typically more than 10) monosaccharide residues linked glycosidically, occurring at the level of an individual cell.

EXT1, EXT2

GO:0033693

BP

neurofilament bundle assembly

The assembly of neurofilaments into bundles, in which the filaments are longitudinally oriented, with numerous crossbridges between them. Neurofilament bundles may be cross-linked to each other, to membrane-bounded organelles or other cytoskeletal structures such as microtubules.

NEFH

GO:0033700

BP

phospholipid efflux

The directed movement of a phospholipid out of a cell or organelle.

ABCA1, APOA1, APOE, APOA2, APOC1, APOC3, APOA5

GO:0033737

MF

1-pyrroline dehydrogenase activity

Catalysis of the reaction: 1-pyrroline + NAD+ + 2 H2O = 4-aminobutanoate + NADH + 2 H+.

ALDH9A1

GO:0033743

MF

peptide-methionine (R)-S-oxide reductase activity

Catalysis of the reaction: peptide-L-methionine + H(2)O + thioredoxin disulfide = peptide-L-methionine (R)-S-oxide + thioredoxin. Can act on oxidized methionine in peptide linkage with specificity for the R enantiomer. Thioredoxin disulfide is the oxidized form of thioredoxin.

MSRB3, TXN2

GO:0033746

MF

histone demethylase activity (H3-R2 specific)

Catalysis of the removal of a methyl group from arginine at position 2 of the histone H3 protein.

JMJD6

GO:0033749

MF

histone demethylase activity (H4-R3 specific)

Catalysis of the removal of a methyl group from arginine at position 3 of the histone H4 protein.

JMJD6

GO:0033762

BP

response to glucagon

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucagon stimulus.

CYC1, QDPR, PFKFB1, CREB1, CCNA2, SREBF1, CRY1, CDO1

GO:0033778

MF

7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase activity

Catalysis of the reaction: 7alpha-hydroxycholest-4-en-3-one + H(+) + NADPH + O(2) = 7alpha,12alpha-dihydroxycholest-4-en-3-one + H(2)O + NADP(+).

CYP8B1

GO:0033780

MF

taurochenodeoxycholate 6alpha-hydroxylase activity

Catalysis of the reactions: taurochenodeoxycholate + NADPH + H+ + O2 = taurohyocholate + NADP+ + H2O, and lithocholate + NADPH + H+ + O2 = hyodeoxycholate + NADP+ + H2O.

CYP3A4

GO:0033791

MF

3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity

Catalysis of the reaction: (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA + H2O + acceptor = (24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestan-26-oyl-CoA + reduced acceptor.

ACOX2

GO:0033814

MF

propanoyl-CoA C-acyltransferase activity

Catalysis of the reaction: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA + propanoyl-CoA = CoA + 3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestanoyl-CoA.

SCP2

GO:0033857

MF

diphosphoinositol-pentakisphosphate kinase activity

Catalysis of the reaction: ATP + 1D-myo-inositol 5-diphosphate pentakisphosphate = ADP + 1D-myo-inositol bisdiphosphate tetrakisphosphate.

PPIP5K1

GO:0033858

MF

N-acetylgalactosamine kinase activity

Catalysis of the reaction: ATP + N-acetyl-D-galactosamine = ADP + N-acetyl-alpha-D-galactosamine 1-phosphate.

GALK2

GO:0033861

BP

negative regulation of NAD(P)H oxidase activity

Any process that stops or reduces the activity of the enzyme NAD(P)H oxidase.

INS

GO:0033862

MF

UMP kinase activity

Catalysis of the reaction: ATP + UMP = ADP + UDP.

CMPK2

GO:0033864

BP

positive regulation of NAD(P)H oxidase activity

Any process that activates or increases the activity of the enzyme NAD(P)H oxidase.

AGT, AGTR1, RFK

GO:0033867

MF

Fas-activated serine/threonine kinase activity

Catalysis of the reaction: ATP + Fas-activated serine/threonine protein = ADP + Fas-activated serine/threonine phosphoprotein.

FASTK

GO:0033872

MF

[heparan sulfate]-glucosamine 3-sulfotransferase 3 activity

Catalysis of the reaction: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate.

HS3ST3B1

GO:0033878

MF

hormone-sensitive lipase activity

Catalysis of the reactions: diacylglycerol + H2O = monoacylglycerol + a carboxylate; triacylglycerol + H2O = diacylglycerol + a carboxylate; and monoacylglycerol + H2O = glycerol + a carboxylate.

LIPE

GO:0033882

MF

choloyl-CoA hydrolase activity

Catalysis of the reaction: choloyl-CoA + H2O = cholate + CoA.

ACOT8

GO:0033897

MF

ribonuclease T2 activity

Catalysis of the two-stage endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides with 2',3'-cyclic phosphate intermediates.

RNASET2

GO:0033906

MF

hyaluronoglucuronidase activity

Catalysis of the random hydrolysis of 1,3-linkages between beta-D-glucuronate and N-acetyl-D-glucosamine residues in hyaluronate.

HYAL2

GO:0033919

MF

glucan 1,3-alpha-glucosidase activity

Catalysis of the hydrolysis of terminal (1->3)-alpha-D-glucosidic links in 1,3-alpha-D-glucans.

GANAB

GO:0033925

MF

mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity

Catalysis of the endohydrolysis of the N,N'-diacetylchitobiosyl unit in high-mannose glycopeptides and glycoproteins containing the -[Man(GlcNAc)2]Asn-structure. One N-acetyl-D-glucosamine residue remains attached to the protein; the rest of the oligosaccharide is released intact.

ENGASE

GO:0033961

MF

cis-stilbene-oxide hydrolase activity

Catalysis of the reaction: cis-stilbene oxide + H2O = (+)-(1R,2R)-1,2-diphenylethane-1,2-diol.

EPHX1

GO:0033962

BP

cytoplasmic mRNA processing body assembly

The aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic mRNA processing body.

LSM3, DYNC1H1, LSM14A, EDC3, LIMD1, CNOT7, NOCT, LSM4

GO:0033981

MF

D-dopachrome decarboxylase activity

Catalysis of the reaction: D-dopachrome + H(+) = 5,6-dihydroxyindole + CO(2).

DDT

GO:0033989

MF

3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity

Catalysis of the reaction: (24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA = (24E)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA + H2O.

HSD17B4

GO:0033993

BP

response to lipid

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus.

VPS4B, CD36, PPARG, HRSP12

GO:0034012

MF

FAD-AMP lyase (cyclizing) activity

Catalysis of the reaction: FAD = AMP + riboflavin cyclic-4',5'-phosphate.

TKFC

GO:0034038

MF

deoxyhypusine synthase activity

Catalysis of the reaction: [eIF5A-precursor]-lysine + spermidine = [eIF5A-precursor]-deoxyhypusine + propane-1,3-diamine. Four sub-reactions have been identified,in which the intermediates remain tightly associated with the enzyme: spermidine + NAD+ = dehydrospermidine + NADH; dehydrospermidine + [enzyme]-lysine = N-(4-aminobutylidene)-[enzyme]-lysine + propane-1,3-diamine; N-(4-aminobutylidene)-[enzyme]-lysine + [eIF5A-precursor]-lysine = N-(4-aminobutylidene)-[eIF5A-precursor]-lysine + [enzyme]-lysine; N-(4-aminobutylidene)-[eIF5A-precursor]-lysine + NADH + H+ = [eIF5A-precursor]-deoxyhypusine + NAD+.

DHPS

GO:0034045

CC

pre-autophagosomal structure membrane

A cellular membrane associated with the pre-autophagosomal structure.

ULK1, ATG12, RAB7A, WIPI1, RB1CC1, ATG2B, RAB1B, WDR45, WIPI2

GO:0034046

MF

poly(G) binding

Interacting selectively and non-covalently with a sequence of guanine residues in an RNA molecule.

ATXN1, HNRNPU, FMR1, PNPT1

GO:0034047

BP

regulation of protein phosphatase type 2A activity

Any process that modulates the activity of the enzyme protein phosphatase type 2A.

ENSA, PPP2R1A, PPP2R1B, HTT, ARPP19, IGBP1, SET, PPP2R3A, PPP2R5C, PPP2R5D, PPP2R5A, PPP2R5B, PPP2R4, ANKLE2, PPME1

GO:0034048

BP

negative regulation of protein phosphatase type 2A activity

Any process that stops or reduces the activity of the enzyme protein phosphatase type 2A.

MASTL

GO:0034056

MF

estrogen response element binding

Interacting selectively and non-covalently with the estrogen response element (ERE), a conserved sequence found in the promoters of genes whose expression is regulated in response to estrogen.

TOX3, ESR1, ESR2

GO:0034057

MF

RNA strand-exchange activity

Facilitates the displacement of one strand of an RNA-RNA duplex and its replacement with a different strand of higher complementarity.

EIF4B

GO:0034058

BP

endosomal vesicle fusion

The homotypic fusion of endocytic vesicles to form or add to an early endosome.

VPS8, ANKFY1

GO:0034059

BP

response to anoxia

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating a decline in oxygen levels to trace amounts, <0.1%.

CTGF, OXTR

GO:0034062

MF

RNA polymerase activity

Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); the synthesis of RNA from ribonucleotide triphosphates in the presence of a nucleic acid template.

TRNT1

GO:0034063

BP

stress granule assembly

The aggregation, arrangement and bonding together of proteins and RNA molecules to form a stress granule.

DDX3X, CIRBP, DYNC1H1, PUM2, ATXN2L, BICD1

GO:0034067

BP

protein localization to Golgi apparatus

A process in which a protein is transported to, or maintained in, a location within the Golgi apparatus.

OBSL1, CSNK1D, GBF1

GO:0034080

BP

CENP-A containing nucleosome assembly

The formation of nucleosomes containing the histone H3 variant CENP-A to form centromeric chromatin. This specialised chromatin occurs at centromeric region in point centromeres, and the central core in modular centromeres.

STRA13, OIP5, SMARCA5, NPM1, CENPA, HIST1H4A, CENPC, RBBP4, ITGB3BP, CENPW, MIS18BP1, CENPU, CENPQ, CENPL, APITD1, HJURP, CASC5, CENPN, RSF1, CENPK, CENPO, CENPH, CENPM, MIS18A, RUVBL1

GO:0034088

BP

maintenance of mitotic sister chromatid cohesion

The process in which the association between sister chromatids of a replicated chromosome is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a mitotic cell cycle.

RB1, NIPBL, DSCC1

GO:0034097

BP

response to cytokine

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus.

PTGES, ALDH1A2, TIMP1, FOS, COL3A1, TYMS, JUN, IL6R, SPARC, BCL2, SKIL, FOSL1, TIMP2, JUNB, JUND, AVPR2, OXTR, DDOST, PLA2G5, IL6ST, LIFR, MAPKAPK2, PGGT1B, RELB, REL, MCL1, OSMR, CITED1, CXCL16, TNFRSF11A

GO:0034098

CC

VCP-NPL4-UFD1 AAA ATPase complex

A multiprotein ATPase complex required for the efficient dislocation of ER-lumenal degradation substrates, and their subsequent proteolysis by the proteasome. In budding yeast, this complex includes Cdc48p, Npl4p and Ufd1p proteins. In mammals, this complex includes a hexamer of VCP/p97 (a cytosolic ATPase) and trimers of each of its cofactors UFD1L and NPL4 (NPLOC4) (e.g. a 6:3:3 stoichiometry).

UBXN7, VCP, CAV1, UFD1L, FAF2, FAF1

GO:0034101

BP

erythrocyte homeostasis

Any process of regulating the production and elimination of erythrocytes within an organism.

GPI, RPS17, HMOX1, AMPD3, PRDX1

GO:0034103

BP

regulation of tissue remodeling

Any process that modulates the frequency, rate, or extent of tissue remodeling.

CST3, THBS4

GO:0034104

BP

negative regulation of tissue remodeling

Any process that stops, prevents, or reduces the frequency, rate, or extent of tissue remodeling.

AGT

GO:0034105

BP

positive regulation of tissue remodeling

Any process that activates or increases the frequency, rate, or extent of tissue remodeling.

IL18

GO:0034109

BP

homotypic cell-cell adhesion

The attachment of a cell to a second cell of the identical type via adhesion molecules.

PLPP3, MEGF10

GO:0034111

BP

negative regulation of homotypic cell-cell adhesion

Any process that stops, prevents, or reduces the frequency, rate, or extent of homotypic cell-cell adhesion.

RDX

GO:0034112

BP

positive regulation of homotypic cell-cell adhesion

Any process that activates or increases the frequency, rate, or extent of homotypic cell-cell adhesion.

TNFSF11, CCL5, ANK3

GO:0034113

BP

heterotypic cell-cell adhesion

The attachment of a cell to a cell of a different type via adhesion molecules.

ITGB3, ITGB2, ITGB1, ITGAV, ITGA5, CD1D, CD58, ITGAX, GLDN, NRCAM, PERP, PARVA

GO:0034115

BP

negative regulation of heterotypic cell-cell adhesion

Any process that stops, prevents, or reduces the frequency, rate, or extent of heterotypic cell-cell adhesion.

KLF4, APOA1, IL1RN, IL10, MAP2K5, MAPK7, ADIPOQ, MYADM

GO:0034116

BP

positive regulation of heterotypic cell-cell adhesion

Any process that activates or increases the frequency, rate, or extent of heterotypic cell-cell adhesion.

FLOT1, TNF, IL1B, FGA, FGB, FGG, ALOX15, CD44, IL10, GCNT2

GO:0034120

BP

positive regulation of erythrocyte aggregation

Any process that activates or increases the frequency, rate, or extent of erythrocyte aggregation.

LGALS1

GO:0034121

BP

regulation of toll-like receptor signaling pathway

Any process that modulates the frequency, rate, or extent of toll-like receptor signaling pathway.

ESR1, BIRC3

GO:0034122

BP

negative regulation of toll-like receptor signaling pathway

Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor signaling pathway.

TYRO3, LGR4, NFKBIL1, IRAK3

GO:0034123

BP

positive regulation of toll-like receptor signaling pathway

Any process that activates or increases the frequency, rate, or extent of toll-like receptor signaling pathway.

TLR3, TLR5, TLR2

GO:0034124

BP

regulation of MyD88-dependent toll-like receptor signaling pathway

Any process that modulates the frequency, rate, or extent of MyD88-dependent toll-like receptor signaling pathway.

IRF1

GO:0034128

BP

negative regulation of MyD88-independent toll-like receptor signaling pathway

Any process that stops, prevents, or reduces the frequency, rate, or extent of MyD88-independent toll-like receptor signaling pathway.

TLR4, TLR3, CD14, SARM1

GO:0034130

BP

toll-like receptor 1 signaling pathway

Any series of molecular signals generated as a consequence of binding to toll-like receptor 1.

TLR1

GO:0034134

BP

toll-like receptor 2 signaling pathway

Any series of molecular signals generated as a consequence of binding to toll-like receptor 2.

RIPK2, TLR2, IRAK1

GO:0034136

BP

negative regulation of toll-like receptor 2 signaling pathway

Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 2 signaling pathway.

LYN, TNFAIP3

GO:0034137

BP

positive regulation of toll-like receptor 2 signaling pathway

Any process that activates or increases the frequency, rate, or extent of toll-like receptor 2 signaling pathway.

F2RL1, TIRAP

GO:0034138

BP

toll-like receptor 3 signaling pathway

Any series of molecular signals generated as a consequence of binding to toll-like receptor 3.

TLR3, RFTN1, COLEC12

GO:0034140

BP

negative regulation of toll-like receptor 3 signaling pathway

Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 3 signaling pathway.

TNFAIP3, F2RL1

GO:0034141

BP

positive regulation of toll-like receptor 3 signaling pathway

Any process that activates or increases the frequency, rate, or extent of toll-like receptor 3 signaling pathway.

FLOT1, F2RL1, TIRAP, CAV1, PELI1, PTPN22

GO:0034142

BP

toll-like receptor 4 signaling pathway

Any series of molecular signals generated as a consequence of binding to toll-like receptor 4.

TLR4, RIPK2, ITGB2, CD14, ITGAM, IRAK1, TIRAP, NR1H4

GO:0034144

BP

negative regulation of toll-like receptor 4 signaling pathway

Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 4 signaling pathway.

LYN, NR1D1, TNFAIP3, BPIFB1

GO:0034145

BP

positive regulation of toll-like receptor 4 signaling pathway

Any process that activates or increases the frequency, rate, or extent of toll-like receptor 4 signaling pathway.

F2RL1, TIRAP, NR1H3, PELI1, PTPN22

GO:0034146

BP

toll-like receptor 5 signaling pathway

Any series of molecular signals generated as a consequence of binding to toll-like receptor 5.

TLR5

GO:0034148

BP

negative regulation of toll-like receptor 5 signaling pathway

Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 5 signaling pathway.

TNFAIP3

GO:0034162

BP

toll-like receptor 9 signaling pathway

Any series of molecular signals generated as a consequence of binding to toll-like receptor 9.

IRAK2, IRAK1, PIK3C3, NR1H4, PIK3R4

GO:0034165

BP

positive regulation of toll-like receptor 9 signaling pathway

Any process that activates or increases the frequency, rate, or extent of toll-like receptor 9 signaling pathway.

HMGB1

GO:0034184

BP

positive regulation of maintenance of mitotic sister chromatid cohesion

Any process that increases the extent to which the association between sister chromatids of a replicated chromosome is maintained during a mitotic cell cycle.

H2AFY, SLF2, SMC5, SLF1

GO:0034185

MF

apolipoprotein binding

Interacting selectively and non-covalently with an apolipoprotein, the protein component of a lipoprotein complex.

LRP6, ABCA1, PLG, LPL, MAPT, CANX, VLDLR, PCSK9, SCARB1

GO:0034186

MF

apolipoprotein A-I binding

Interacting selectively and non-covalently with apolipoprotein A-I.

ABCA1, SCARB1

GO:0034188

MF

apolipoprotein A-I receptor activity

Combining with apolipoprotein A-I and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.

ABCA1

GO:0034189

MF

very-low-density lipoprotein particle binding

Interacting selectively and non-covalently with a very-low-density lipoprotein particle, a triglyceride-rich lipoprotein particle that is typically composed of APOB100, APOE and APOCs and has a density of about 1.006 g/ml and a diameter of between 20-80 nm.

VLDLR, PCSK9

GO:0034190

MF

apolipoprotein receptor binding

Interacting selectively and non-covalently with an apolipoprotein receptor.

APOA1, APOA2, PCSK9

GO:0034191

MF

apolipoprotein A-I receptor binding

Interacting selectively and non-covalently with an apolipoprotein A-I receptor.

APOA1, NR1H2, CDC42