GO:0033211

BP

adiponectin-activated signaling pathway

A series of molecular signals initiated by the binding of adiponectin to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.

ACSL1, ADIPOQ, SLC27A1, ADIPOR2, ADIPOR1

GO:0033218

MF

amide binding

Interacting selectively and non-covalently with an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group.

SRD5A1, SRD5A2, PHB2

GO:0033227

BP

dsRNA transport

The directed movement of dsRNA, double-stranded ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

FLOT1, RFTN1, RFTN2

GO:0033233

BP

regulation of protein sumoylation

Any process that modulates the frequency, rate or extent of the addition of SUMO groups to a protein.

EGR1

GO:0033234

BP

negative regulation of protein sumoylation

Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of SUMO groups to a protein.

CAPN3, CTNNB1, GNL3L, HMG20B

GO:0033235

BP

positive regulation of protein sumoylation

Any process that activates or increases the frequency, rate or extent of the addition of SUMO groups to a protein.

ARNT, HDAC4, RASD2, GNL3, TOLLIP

GO:0033256

CC

I-kappaB/NF-kappaB complex

A protein complex containing an inhibitory-kappaB (I-kappaB/IKB) protein and one or more copies of an NF-kappaB protein. In the resting state, NF-kappaB dimers are bound to I-kappaB proteins, sequestering NF-kappaB in the cytoplasm.

NFKB1, RELB, RELA, REL

GO:0033257

CC

Bcl3/NF-kappaB2 complex

A protein complex containing one Bcl protein and one or more copies of NF-kappaB2; formation of complexes of different stoichiometry depends on the Bcl3:NF-kappaB2 ratio, and allow Bcl3 to exert different regulatory effects on NF-kappaB2-dependent transcription.

BCL3

GO:0033260

BP

nuclear DNA replication

The DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle.

SLBP, DONSON

GO:0033262

BP

regulation of nuclear cell cycle DNA replication

Any process that modulates the frequency, rate or extent of The DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle.

TIPIN, CDT1, DACH1

GO:0033263

CC

CORVET complex

A multimeric protein complex that acts as an endosomal tethering complex (CORVET = class C core vacuole/endosome tethering) by cooperating with Rab GTPases to capture endosomal vesicles and trap them prior to the action of SNAREs; the complex is involved in endo-lysosomal biogenesis and required for transport between endosome and vacuole. The Saccharomyces cerevisiae complex contains Vps8p, Vps3p, Pep5p, Vps16p, Pep3p, and Vps33p.

VPS8

GO:0033265

MF

choline binding

Interacting selectively and non-covalently with choline, the amine 2-hydroxy-N,N,N-trimethylethanaminium.

CRP, CHKA

GO:0033268

CC

node of Ranvier

An axon part that is a gap in the myelin where voltage-gated sodium channels cluster and saltatory conduction is executed.

BIN1, ANK3, DLG1, DAG1, SPTBN4

GO:0033269

CC

internode region of axon

An axon part that is located between the nodes of Ranvier and surrounded by compact myelin sheath.

TUBB4A, PARD3

GO:0033270

CC

paranode region of axon

An axon part that is located adjacent to the nodes of Ranvier and surrounded by lateral loop portions of myelin sheath.

MAG, KCNA1, ANK3, SIRT2, SPTBN4, KIF13B, EPB41L3

GO:0033273

BP

response to vitamin

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin stimulus.

PEMT

GO:0033274

BP

response to vitamin B2

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B2 stimulus.

MTHFR

GO:0033275

BP

actin-myosin filament sliding

The sliding movement of actin thin filaments and myosin thick filaments past each other.

ACTC1

GO:0033276

CC

transcription factor TFTC complex

A protein complex that does not contain either a TATA-binding protein (TBP) or a TBP-like factor, but is composed of several TAFIIs and other proteins, including a histone acetyltransferase. This complex is able to nucleate transcription initiation by RNA polymerase II, can mediate transcriptional activation, and has histone acetyltransferase activity.

SUPT3H, TADA3, TAF10, TAF5, TAF12, TAF9B, TRRAP

GO:0033277

BP

abortive mitotic cell cycle

A cell cycle in which mitosis is begun and progresses normally through the end of anaphase, but not completed, resulting in a cell with increased ploidy.

PTPN11

GO:0033278

BP

cell proliferation in midbrain

The multiplication or reproduction of cells, resulting in the expansion of a cell population in the midbrain.

FZD6, WNT2

GO:0033280

BP

response to vitamin D

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin D stimulus.

CYP27B1, STC2, TGFB1, PTH, CD4, BGLAP, ALPL, SPP1, TYR, PTGS2, STC1, TRIM25, TPCN2, AQP3

GO:0033290

CC

eukaryotic 48S preinitiation complex

A protein complex composed of the small ribosomal subunit, eIF3, eIF1A, methionyl-initiatior methionine and a capped mRNA. The complex is initially positioned at the 5'-end of the capped mRNA.

EIF3J, EIF2S1, EIF3B, EIF3A, EIF3K

GO:0033291

CC

eukaryotic 80S initiation complex

A protein complex composed of the large and small ribosomal subunits, methionyl-initiatior tRNA, and the capped mRNA. The initiator tRNA is positioned at the ribosomal P site at the AUG codon corresponding to the beginning of the coding region.

RPL38

GO:0033292

BP

T-tubule organization

A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of the T-tubule. A T-tubule is an invagination of the plasma membrane of a muscle cell that extends inward from the cell surface around each myofibril.

ATP2A2, ANK2

GO:0033299

BP

secretion of lysosomal enzymes

The controlled release of lysosomal enzymes by a cell.

GNPTAB, NAGPA, BLOC1S6

GO:0033300

MF

dehydroascorbic acid transporter activity

Enables the directed movement of dehydroascorbate, 5-(1,2-dihydroxyethyl)furan-2,3,4(5H)-trione, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

SLC2A1, SLC2A3

GO:0033301

BP

cell cycle comprising mitosis without cytokinesis

A mitotic cell cycle in which mitosis is completed but cytokinesis does not occur, resulting in a cell containing multiple nuclei each with a chromosomal complement of the original ploidy (usually 2N).

E2F8

GO:0033306

BP

phytol metabolic process

The chemical reactions and pathways involving phytol, (2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-en-1-ol.

ALDH3A2

GO:0033313

BP

meiotic cell cycle checkpoint

A cell cycle checkpoint that ensures accurate chromosome replication and segregation by preventing progression through a meiotic cell cycle until conditions are suitable for the cell to proceed to the next stage.

NSUN2

GO:0033314

BP

mitotic DNA replication checkpoint

A cell cycle checkpoint that acts during a mitotic cell cycle and prevents the initiation of mitosis until DNA replication is complete, thereby ensuring that progeny inherit a full complement of the genome.

NAE1, TOPBP1, SLF1

GO:0033320

BP

UDP-D-xylose biosynthetic process

The chemical reactions and pathways resulting in the formation of UDP-D-xylose, uridinediphosphoxylose, a substance composed of xylose in glycosidic linkage with uridine diphosphate.

UXS1

GO:0033327

BP

Leydig cell differentiation

The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Leydig cell. A Leydig cell is a testosterone-secreting cell in the interstitial area, between the seminiferous tubules, in the testis.

DHH, AR, MGST1, NKX2-1, NR0B1, TMF1

GO:0033343

BP

positive regulation of collagen binding

Any process that activates or increases the frequency, rate or extent of collagen binding.

ITGA2

GO:0033344

BP

cholesterol efflux

The directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle.

NPC1, ABCA1, APOA1, APOE, APOA2, APOC1, APOC3, APOB, SOAT1, NPC2, APOA5, SCARB1, ABCA5, ABCG8

GO:0033345

BP

asparagine catabolic process via L-aspartate

The chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate L-aspartate.

ASRGL1

GO:0033353

BP

S-adenosylmethionine cycle

A cyclic series of interconversions involving S-adenosylmethionine, S-adenosyl-L-homocysteine, L-cysteine, and L-methionine. Couples utilization of the methyl group of SAM with recycling of the homocysteinyl group and regeneration of methionine.

AHCYL1, AHCY

GO:0033363

BP

secretory granule organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion.

SERPINE2, CREB1

GO:0033364

BP

mast cell secretory granule organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule in a mast cell. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion.

SRGN, LYST

GO:0033365

BP

protein localization to organelle

A process in which a protein is transported to, or maintained in, a location within an organelle.

AP3D1, ANK2, CROCC, BICD1, BBS2

GO:0033368

BP

protease localization to mast cell secretory granule

Any process in which a protease is transported to, or maintained in, a location within a secretory granule in a mast cell.

SRGN

GO:0033371

BP

T cell secretory granule organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule in a T cell. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion.

SRGN

GO:0033373

BP

maintenance of protease location in mast cell secretory granule

A process in which a protease is maintained in a secretory granule in a mast cell and prevented from moving elsewhere.

SRGN

GO:0033382

BP

maintenance of granzyme B location in T cell secretory granule

A process in which the protease granyme B is maintained in a secretory granule in a T cell and prevented from moving elsewhere.

SRGN

GO:0033384

BP

geranyl diphosphate biosynthetic process

The chemical reactions and pathways resulting in the formation of geranyl diphosphate.

FDPS

GO:0033387

BP

putrescine biosynthetic process from ornithine

The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane by decarboxylation of ornithine.

AZIN1, ODC1

GO:0033388

BP

putrescine biosynthetic process from arginine

The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane, from other compounds, including arginine.

AGMAT

GO:0033391

CC

chromatoid body

A ribonucleoprotein complex found in the cytoplasm of male germ cells, composed of exceedingly thin filaments that are consolidated into a compact mass or into dense strands of varying thickness that branch to form an irregular network. Contains mRNAs, miRNAs, and protein components involved in miRNA processing (such as Argonaute proteins and the endonuclease Dicer) and in RNA decay (such as the decapping enzyme DCP1a and GW182).

ARNTL, EIF4E, NSUN2

GO:0033484

BP

nitric oxide homeostasis

A homeostatic process involved in the maintenance of an internal steady state of nitric oxide within an organism or cell.

CAV1

GO:0033488

BP

cholesterol biosynthetic process via 24,25-dihydrolanosterol

The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, via the intermediate 24,25-dihydrolanosterol.

CYP51A1

GO:0033489

BP

cholesterol biosynthetic process via desmosterol

The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, via the intermediate desmosterol.

SC5D, EBP, DHCR24, DHCR7

GO:0033490

BP

cholesterol biosynthetic process via lathosterol

The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, via the intermediate lathosterol.

SC5D, EBP, DHCR24, DHCR7

GO:0033503

CC

HULC complex

A ubiquitin-conjugating enzyme complex that contains two RING finger proteins, which have ubiquitin ligase activity, in addition to a protein with ubiquitin-conjugating enzyme activity; catalyzes the ubiquitination of histone H2B at lysine 119 (or the equivalent residue). In Schizosaccharomyces the subunits are Rhp1, Brl2/Rfp1 and Brl1/Rfp2.

UBE2A, UBE2B

GO:0033504

BP

floor plate development

The progression of the floor plate over time from its initial formation until its mature state.

COBL, STIL

GO:0033512

BP

L-lysine catabolic process to acetyl-CoA via saccharopine

The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including acetyl-CoA, via the intermediate saccharopine.

DLST, AASS

GO:0033514

BP

L-lysine catabolic process to acetyl-CoA via L-pipecolate

The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including acetyl-CoA, via the intermediate L-pipecolate.

PIPOX

GO:0033522

BP

histone H2A ubiquitination

The modification of histone H2A by addition of one or more ubiquitin groups.

RNF8, UBE2A, UBE2B

GO:0033523

BP

histone H2B ubiquitination

The modification of histone H2B by addition of ubiquitin groups.

RNF8, UBE2E1

GO:0033539

BP

fatty acid beta-oxidation using acyl-CoA dehydrogenase

A fatty acid beta-oxidation pathway in which the initial step of each oxidation cycle, which converts an acyl-CoA to a trans-2-enoyl-CoA, is catalyzed by acyl-CoA dehydrogenase; the electrons removed by oxidation pass through the respiratory chain to oxygen and leave H2O as the product. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).

ACOX3, ACADSB, ACADVL, ACOX1, ETFDH, ACOX2

GO:0033540

BP

fatty acid beta-oxidation using acyl-CoA oxidase

A fatty acid beta-oxidation pathway in which the initial step, which converts an acyl-CoA to a trans-2-enoyl-CoA, is catalyzed by acyl-CoA oxidase; the electrons removed by oxidation pass directly to oxygen and produce hydrogen peroxide, which is cleaved by peroxisomal catalases. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).

NUDT19, ACOT8, ACOX3, SCP2, CRAT, HSD17B4, ACOX1, ACOX2, CROT

GO:0033549

MF

MAP kinase phosphatase activity

Catalysis of the reaction: a phosphorylated MAP kinase + H2O = a MAP kinase + phosphate.

DUSP3, DUSP10

GO:0033552

BP

response to vitamin B3

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B3 stimulus.

CCL2

GO:0033555

BP

multicellular organismal response to stress

Any process that results in a change in state or activity of a multicellular organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).

LGALS1, ADCYAP1R1, PTEN, PPP3CA, SEPN1

GO:0033558

MF

protein deacetylase activity

Catalysis of the hydrolysis of an acetyl group or groups from a protein substrate.

HDAC3, HDAC4, HDAC1, SIRT2, HDAC2, HDAC9, HDAC5

GO:0033560

MF

folate reductase activity

Catalysis of the reaction: 7,8-dihydrofolate + NADP+ = folate + NADPH + H+.

DHFR

GO:0033564

BP

anterior/posterior axon guidance

The process in which the migration of an axon growth cone is directed to a specific target site along the anterior-posterior body axis in response to a combination of attractive and repulsive cues. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.

UNC5C, UNC5B

GO:0033565

CC

ESCRT-0 complex

A protein complex required for the recycling of Golgi proteins, formation of lumenal membranes and sorting of ubiquitinated proteins into those membranes. This complex includes Vps1p and Hse1p in yeast and the Hrs and STAM proteins in mammals.

STAM2, STAM

GO:0033566

BP

gamma-tubulin complex localization

Any process in which a gamma-tubulin complex is transported to, or maintained in, a specific location.

MZT1

GO:0033567

BP

DNA replication, Okazaki fragment processing

The DNA metabolic process, occurring during lagging strand synthesis, by which RNA primers are removed from Okazaki fragments, the resulting gaps filled by DNA polymerization, and the ends ligated to form a continuous strand.

DNA2

GO:0033570

MF

transferrin transmembrane transporter activity

Enables the transfer of transferrin from one side of a membrane to the other.

TFRC, SLC11A2

GO:0033572

BP

transferrin transport

The directed movement of transferrin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

ATP6V0E1, ATP6V1G1, ATP6V1G2, TFRC, TF, ATP6V1B2, ATP6V1C1, SLC11A2, ATP6V0D1, TCIRG1, RAB11B, ATP6V1F, ATP6V1C2, ATP6V0A1, ATP6V1H, TFR2, ATP6V1D

GO:0033574

BP

response to testosterone

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a testosterone stimulus.

MSTN, GNRH1, BGLAP, EDN1, GPI, THBS1, CDK4, NME1, PLN, CAD, CALR, DUSP1, TSPO, SRD5A2, NASP, HSF1, MTAP, KCNJ11, BAD

GO:0033578

BP

protein glycosylation in Golgi

The addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid in any compartment of the Golgi apparatus.

LMF1, FUT8

GO:0033588

CC

Elongator holoenzyme complex

A heterohexameric protein complex that is involved in modification of wobble nucleosides in tRNA. The complex can associate physically with hyperphosphorylated RNA polymerase II; it contains two discrete heterotrimeric subcomplexes.

IKBKAP, ELP6, ELP4, ELP3

GO:0033590

BP

response to cobalamin

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalamin (vitamin B12) stimulus.

EGFR, RELA

GO:0033591

BP

response to L-ascorbic acid

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an L-ascorbic acid (vitamin C) stimulus.

GSTP1, SPARC, ITGA2

GO:0033592

MF

RNA strand annealing activity

Facilitates the base-pairing of complementary single-stranded RNA.

EIF4B, FXR1, FMR1

GO:0033593

CC

BRCA2-MAGE-D1 complex

A heterodimeric protein complex formed of BRCA2 and MAGE-D1; may mediate the synergistic activities of the two proteins in regulating cell growth.

BRCA2

GO:0033594

BP

response to hydroxyisoflavone

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroxyisoflavone stimulus.

EGFR, BGLAP

GO:0033596

CC

TSC1-TSC2 complex

A protein complex consisting of at least tumerin and hamartin; its formation may regulate hamartin homomultimer formation. The complex acts as a GTPase activating protein (GAP) for the small GTPase (Rheb), and inhibits the TOR signaling pathway.

TSC2

GO:0033597

CC

mitotic checkpoint complex

A multiprotein complex that functions as a mitotic checkpoint inhibitor of the anaphase-promoting complex/cyclosome (APC/C). In budding yeast this complex consists of Mad2p, Mad3p, Bub3p and Cdc20p, and in mammalian cells it consists of MAD2, BUBR1, BUB3, and CDC20.

BUB3

GO:0033598

BP

mammary gland epithelial cell proliferation

The multiplication or reproduction of mammary gland epithelial cells, resulting in the expansion of a cell population. Mammary gland epithelial cells make up the covering of surfaces of the mammary gland. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk.

TNFSF11, CEBPB, MAPK1, ID2, BTRC

GO:0033599

BP

regulation of mammary gland epithelial cell proliferation

Any process that modulates the frequency, rate or extent of mammary gland epithelial cell proliferation.

GPX1, BAX, PYGO2

GO:0033600

BP

negative regulation of mammary gland epithelial cell proliferation

Any process that stops, prevents or reduces the rate or extent of mammary gland epithelial cell proliferation.

BRCA2, PHB2

GO:0033601

BP

positive regulation of mammary gland epithelial cell proliferation

Any process that activates or increases the rate or extent of mammary gland epithelial cell proliferation.

IQGAP3, KDM5B

GO:0033602

BP

negative regulation of dopamine secretion

Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of dopamine.

DRD2, CNR1, ABAT

GO:0033603

BP

positive regulation of dopamine secretion

Any process that activates or increases the frequency, rate or extent of the regulated release of dopamine.

CXCL12, NPY2R, PINK1

GO:0033612

MF

receptor serine/threonine kinase binding

Interacting selectively and non-covalently with a receptor that possesses protein serine/threonine kinase activity.

BMP10

GO:0033613

MF

activating transcription factor binding

Interacting selectively and non-covalently with an activating transcription factor, any protein whose activity is required to initiate or upregulate transcription.

PPARG, GATA4, HDAC4, MEF2A, RELA, MEF2C, EP300, HDAC1, MEF2D, SMAD2, HDAC7, ATOH8

GO:0033615

BP

mitochondrial proton-transporting ATP synthase complex assembly

The aggregation, arrangement and bonding together of a proton-transporting ATP synthase in the mitochondrial inner membrane.

ATPAF1

GO:0033617

BP

mitochondrial respiratory chain complex IV assembly

The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex IV (also known as cytochrome c oxidase) in the mitochondrial inner membrane.

PET100, COX17, COX19, COX20, COX14, TIMM21, COA4, BCS1L, COA3

GO:0033619

BP

membrane protein proteolysis

The proteolytic cleavage of a transmembrane protein leading to the release of its intracellular or ecto-domains.

CTSH, TMPRSS6, SPPL3, SPPL2A, HM13

GO:0033622

BP

integrin activation

The aggregation, arrangement and bonding together of an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits, that lead to the increased affinity of the integrin for its extracellular ligands.

ITGB1BP1, FN1, COL16A1

GO:0033623

BP

regulation of integrin activation

Any process that modulates the frequency, rate, or extent of integrin activation.

FARP2, FBLIM1

GO:0033624

BP

negative regulation of integrin activation

Any process that stops, prevents, or reduces the frequency, rate, or extent of integrin activation.

PTGER4, KIF14

GO:0033625

BP

positive regulation of integrin activation

Any process that activates or increases the frequency, rate, or extent of integrin activation.

PIEZO1

GO:0033626

BP

positive regulation of integrin activation by cell surface receptor linked signal transduction

Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell that lead to the increased affinity of an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits, for its extracellular ligands.

CDH17

GO:0033627

BP

cell adhesion mediated by integrin

The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits.

VTN, ITGB3, ICAM1, ITGB1, ITGAV, ITGA5, ITGA2, ITGA6, FBN1, ADAM17, COL16A1, ADAM9, ITGA11

GO:0033628

BP

regulation of cell adhesion mediated by integrin

Any process that modulates the frequency, rate, or extent of cell adhesion mediated by integrin.

ITGB1BP1, LPXN, PLAU, LYN, EFNA1, PIK3CG, PTK2, PTPN11

GO:0033629

BP

negative regulation of cell adhesion mediated by integrin

Any process that stops, prevents, or reduces the frequency, rate, or extent of cell adhesion mediated by integrin.

SNAI2, SERPINE1, MUC1, PTPN11, PDE3B, CYP1B1