| GO ID | Ontology | GO Term | Term Definition |
Proteins |
GO:0032732 | BP | positive regulation of interleukin-1 production | Any process that activates or increases the frequency, rate, or extent of interleukin-1 production. |
TLR4, HDAC1, HDAC2 |
GO:0032733 | BP | positive regulation of interleukin-10 production | Any process that activates or increases the frequency, rate, or extent of interleukin-10 production. |
TLR4, TLR2, TUSC2, SASH3, HMGB1, CD28, HSPD1, HGF, CD46, TNFSF4, CD40LG, CD83, PIBF1 |
GO:0032735 | BP | positive regulation of interleukin-12 production | Any process that activates or increases the frequency, rate, or extent of interleukin-12 production. |
TLR4, TLR3, RIPK2, TLR2, HMGB1, HSPD1, CD36, HLA-G, TNFSF4, CD40LG, TIRAP, PLCB1 |
GO:0032736 | BP | positive regulation of interleukin-13 production | Any process that activates or increases the frequency, rate, or extent of interleukin-13 production. |
IL33, HLA-E, TNFSF4, IL1RAP |
GO:0032738 | BP | positive regulation of interleukin-15 production | Any process that activates or increases the frequency, rate, or extent of interleukin-15 production. |
TIRAP |
GO:0032740 | BP | positive regulation of interleukin-17 production | Any process that activates or increases the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines. |
TGFB1, PRKCQ, IL18 |
GO:0032741 | BP | positive regulation of interleukin-18 production | Any process that activates or increases the frequency, rate, or extent of interleukin-18 production. |
TLR2 |
GO:0032743 | BP | positive regulation of interleukin-2 production | Any process that activates or increases the frequency, rate, or extent of interleukin-2 production. |
MAP3K7, RIPK2, SASH3, ANXA1, TNFSF4, CD83, RUNX1, PDE4D, PRKD2 |
GO:0032753 | BP | positive regulation of interleukin-4 production | Any process that activates or increases the frequency, rate, or extent of interleukin-4 production. |
SASH3, IL33, CD28, PRG2, HLA-E, CEBPB, ZP3, TNFSF4, CD40LG, PRKCQ, FOXP3 |
GO:0032754 | BP | positive regulation of interleukin-5 production | Any process that activates or increases the frequency, rate, or extent of interleukin-5 production. |
IL33, IL1RL1, PDE4D, IL1RAP |
GO:0032755 | BP | positive regulation of interleukin-6 production | Any process that activates or increases the frequency, rate, or extent of interleukin-6 production. |
TLR4, MAPK13, TLR3, RIPK2, TLR2, IL33, TNF, IL1A, IL1B, IL6, IL6R, HSPD1, CD36, TNFSF4, ADORA2B, WNT5A, ARHGEF2, SPON2, ZBTB20, TBC1D23, PYCARD |
GO:0032757 | BP | positive regulation of interleukin-8 production | Any process that activates or increases the frequency, rate, or extent of interleukin-8 production. |
TLR4, TLR3, TLR5, TLR2, TNF, IL1B, SERPINE1, HSPA1A, HSPA1B, DDIT3, TIRAP, FADD, RIPK1, ADIPOQ, MAVS, AFAP1L2, PRKD2, ZNF580 |
GO:0032759 | BP | positive regulation of TRAIL production | Any process that activates or increases the frequency, rate, or extent of TRAIL production. |
HLA-E |
GO:0032760 | BP | positive regulation of tumor necrosis factor production | Any process that activates or increases the frequency, rate, or extent of tumor necrosis factor production. |
TLR4, TLR3, RIPK2, TLR2, JAK2, SASH3, PF4, CD14, CCL3, CLU, CCL2, HLA-E, CD36, PTAFR, PIK3R1, LEP, TIRAP, FADD, RIPK1, HDAC1, NFATC4, TWIST1, MAVS, HDAC2, ARHGEF2, SPON2, ZBTB20, PYCARD, ARFGEF2 |
GO:0032762 | BP | mast cell cytokine production | Any process that contributes to cytokine production by a mast cell. |
KIT |
GO:0032764 | BP | negative regulation of mast cell cytokine production | Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell cytokine production. |
HMOX1, BCL6 |
GO:0032765 | BP | positive regulation of mast cell cytokine production | Any process that activates or increases the frequency, rate, or extent of mast cell cytokine production. |
BCL10, NR4A3 |
GO:0032767 | MF | copper-dependent protein binding | Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules), in the presence of copper. |
ATOX1, FKBP4 |
GO:0032769 | BP | negative regulation of monooxygenase activity | Any process that stops or reduces the activity of a monooxygenase. |
SNCA |
GO:0032775 | BP | DNA methylation on adenine | The covalent transfer of a methyl group to N-6 of adenine in a DNA molecule. |
METTL4 |
GO:0032777 | CC | Piccolo NuA4 histone acetyltransferase complex | A heterotrimeric H4/H2A histone acetyltransferase complex with a substrate preference of chromatin over free histones. It contains a subset of the proteins found in the larger NuA4 histone acetyltransferase complex; for example, the S. cerevisiae complex contains Esa1p, Yng2p, and Epl1p. |
EPC2, EPC1, ING3 |
GO:0032780 | BP | negative regulation of ATPase activity | Any process that stops or reduces the rate of ATP hydrolysis by an ATPase. |
TNNI3, PLN, PPIF, CNN3, PXK, PAM16 |
GO:0032781 | BP | positive regulation of ATPase activity | Any process that activates or increases the rate of ATP hydrolysis by an ATPase. |
DNAJB6, ATP1B1, PFN1, TPM1, MYL4, DNAJB1, ATP1B3, GABARAPL2, RGN, AHSA2, DNAJC10, DNAJC9, DNAJC1, DNAJC7 |
GO:0032783 | CC | ELL-EAF complex | A heterodimeric protein complex that acts as an RNA polymerase II elongation factor; the complex is conserved from yeast to humans, and is present in S. pombe, but absent from S. cerevisiae. |
EAF1 |
GO:0032784 | BP | regulation of DNA-templated transcription, elongation | Any process that modulates the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides catalyzed by a DNA-dependent RNA polymerase. |
TCEA3, TSFM, ZNF326, CCAR2 |
GO:0032785 | BP | negative regulation of DNA-templated transcription, elongation | Any process that stops, prevents, or reduces the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides catalyzed by a DNA-dependent RNA polymerase. |
SUPT5H |
GO:0032786 | BP | positive regulation of DNA-templated transcription, elongation | Any process that activates or increases the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides catalyzed by a DNA-dependent RNA polymerase. |
SUPT5H, ALYREF, SUPT16H |
GO:0032787 | BP | monocarboxylic acid metabolic process | The chemical reactions and pathways involving monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-). |
CYP2C9 |
GO:0032788 | BP | saturated monocarboxylic acid metabolic process | The chemical reactions and pathways involving saturated monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-) and fully saturated C-C bonds. |
ACOT4 |
GO:0032789 | BP | unsaturated monocarboxylic acid metabolic process | The chemical reactions and pathways involving unsaturated monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-) and one or more unsaturated C-C bonds. |
ACOT4 |
GO:0032790 | BP | ribosome disassembly | The disaggregation of a ribosome into its constituent components; includes the dissociation of ribosomal subunits. |
DENR, MTIF3, HBS1L |
GO:0032791 | MF | lead ion binding | Interacting selectively and non-covalently with lead (Pb) ions. |
ALAD |
GO:0032792 | BP | negative regulation of CREB transcription factor activity | Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the transcription factor CREB. |
DDIT3, SIK1, FOXP3, EIF2AK4 |
GO:0032793 | BP | positive regulation of CREB transcription factor activity | Any process that activates or increases the frequency, rate or extent of activity of the transcription factor CREB. |
RPS6KA5, VEGFA, EPHA5, PRKD1, CRTC3, CAMK1D, PRKD2 |
GO:0032794 | MF | GTPase activating protein binding | Interacting selectively and non-covalently with a GTPase activating protein. |
TUBB, GNAI3, AKT1, PLCD1, GNAI1 |
GO:0032795 | MF | heterotrimeric G-protein binding | Interacting selectively and non-covalently with a heterotrimeric G-protein. |
ADORA1 |
GO:0032796 | BP | uropod organization | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a uropod, a rigid membrane projection with related cytoskeletal components at the trailing edge of a lymphocyte or other cell in the process of migrating or being activated. |
CORO1A, MYH9 |
GO:0032797 | CC | SMN complex | A protein complex that contains the survival motor neuron (SMN) protein and at least eight additional integral components, including the Gemin2-8 and Unrip proteins; the complex is found in the cytoplasm and in nuclear Gems, and is involved in spliceosomal snRNP assembly in the cytoplasm and in pre-mRNA splicing in the nucleus. |
ZPR1, GEMIN4, FMR1, GEMIN5, GEMIN6, GEMIN8, DDX20 |
GO:0032798 | CC | Swi5-Sfr1 complex | A conserved DNA recombinase mediator complex that contains two Swi5 monomers and one Sfr1 monomer in Schizosaccharomyces, or orthologs thereof (e.g. Sae3p and Mei5p in Saccharomyces). |
SWI5 |
GO:0032800 | BP | receptor biosynthetic process | The chemical reactions and pathways resulting in the formation of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function. |
TNF, IL10 |
GO:0032801 | BP | receptor catabolic process | The chemical reactions and pathways resulting in the breakdown of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function. |
TGFB1, CDK5, PIK3R4, SH3GLB1 |
GO:0032802 | BP | low-density lipoprotein particle receptor catabolic process | The chemical reactions and pathways resulting in the breakdown of a low-density lipoprotein particle receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function. |
PCSK9 |
GO:0032803 | BP | regulation of low-density lipoprotein particle receptor catabolic process | Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of low-density lipoprotein particle receptors. |
MYLIP |
GO:0032804 | BP | negative regulation of low-density lipoprotein particle receptor catabolic process | Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of low-density lipoprotein receptors. |
ANXA2, FURIN |
GO:0032805 | BP | positive regulation of low-density lipoprotein particle receptor catabolic process | Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of low-density lipoprotein particle receptors. |
APOE, PCSK9 |
GO:0032807 | CC | DNA ligase IV complex | A eukaryotically conserved protein complex that contains DNA ligase IV and is involved in DNA repair by non-homologous end joining; in addition to the ligase, the complex also contains XRCC4 or a homolog, e.g. Saccharomyces Lif1p. |
XRCC4 |
GO:0032808 | BP | lacrimal gland development | The process whose specific outcome is the progression of the lacrimal gland over time, from its formation to the mature structure. The lacrimal gland produces secretions that lubricate and protect the cornea of the eye. |
FGFR2, SOX9, FOXC1 |
GO:0032809 | CC | neuronal cell body membrane | The plasma membrane of a neuron cell body - excludes the plasma membrane of cell projections such as axons and dendrites. |
ATP2B1, GABRA5, SLC4A8, FLRT1 |
GO:0032810 | MF | sterol response element binding | Interacting selectively and non-covalently with the sterol response element (SRE), a nonpalindromic sequence found in the promoters of genes involved in lipid metabolism. |
SREBF1, NR1H3 |
GO:0032811 | BP | negative regulation of epinephrine secretion | Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of epinephrine. |
ADRA2B |
GO:0032812 | BP | positive regulation of epinephrine secretion | Any process that activates or increases the frequency, rate or extent of the regulated release of epinephrine. |
CARTPT |
GO:0032813 | MF | tumor necrosis factor receptor superfamily binding | Interacting selectively and non-covalently with any member of the tumor necrosis factor receptor superfamily. |
TNFSF11, TNFSF4, FADD |
GO:0032814 | BP | regulation of natural killer cell activation | Any process that modulates the frequency, rate or extent of natural killer cell activation. |
LEP |
GO:0032815 | BP | negative regulation of natural killer cell activation | Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell activation. |
MICA, PIBF1 |
GO:0032816 | BP | positive regulation of natural killer cell activation | Any process that activates or increases the frequency, rate or extent of natural killer cell activation. |
IL12A, BLOC1S6 |
GO:0032817 | BP | regulation of natural killer cell proliferation | Any process that modulates the frequency, rate or extent of natural killer cell proliferation. |
LEP, PTPN22 |
GO:0032819 | BP | positive regulation of natural killer cell proliferation | Any process that activates or increases the frequency, rate or extent of natural killer cell proliferation. |
STAT5B, IL18, CD244 |
GO:0032825 | BP | positive regulation of natural killer cell differentiation | Any process that activates or increases the frequency, rate or extent of natural killer cell differentiation. |
STAT5B, GAS6 |
GO:0032827 | BP | negative regulation of natural killer cell differentiation involved in immune response | Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell differentiation as part of an immune response. |
PGLYRP2 |
GO:0032831 | BP | positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation | Any process that activates or increases the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells. |
FOXP3 |
GO:0032835 | BP | glomerulus development | The progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the vertebrate kidney. The glomerulus is part of the nephron and is restricted to one body segment. |
TCF21, BCL2, WT1, PTPRO, HEYL |
GO:0032836 | BP | glomerular basement membrane development | The process whose specific outcome is the progression of the glomerular basement membrane over time, from its formation to the mature structure. The glomerular basement membrane is the basal laminal portion of the glomerulus which performs the actual filtration. |
NID1, WT1, MPV17, COL4A3, MYO1E, SULF2, SULF1 |
GO:0032838 | CC | cell projection cytoplasm | All of the contents of a cell projection, excluding the plasma membrane surrounding the projection. |
AKR1B1 |
GO:0032839 | CC | dendrite cytoplasm | All of the contents of a dendrite, excluding the surrounding plasma membrane. |
ADA, CANX, MAPK1, DLG4, WLS, UHMK1, GABARAPL1 |
GO:0032848 | BP | negative regulation of cellular pH reduction | Any process that stops, prevents, or reduces the frequency, rate, or extent of a process that reduces the internal pH of a cell. |
BCL2 |
GO:0032849 | BP | positive regulation of cellular pH reduction | Any process that activates or increases the frequency, rate, or extent of a process that reduces the internal pH of a cell. |
CA2 |
GO:0032868 | BP | response to insulin | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms. |
AGRP, OGT, TLR2, IL6, FABP3, LYN, EGR2, PFKFB1, EGR1, IL10, GAL, PLN, CAD, MC4R, ADM, PCK1, IRS1, LEP, TNFSF10, UCP3, EIF6, SESN2, SESN3, HSD11B2, RELA, PPARA, SRSF6, CRY1, HADH, SLC27A1, EPM2AIP1, GGH, UPRT, CITED1, TRPV4, RETN |
GO:0032869 | BP | cellular response to insulin stimulus | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms. |
TBC1D4, INSR, APRT, GSTP1, INHBB, PARP1, CCL2, SLC2A4, RHOQ, XBP1, SRD5A1, ENPP1, PIK3R1, AKT1, AKT2, PCK1, IRS1, PPARG, PRKCI, GCLC, STAR, UCP2, VAMP2, PRKDC, GPLD1, PPAT, ZFP36L1, FOXO1, SRSF5, PDE3B, RAB31, LPIN1, ADIPOQ, DENND4C, CPEB2, C2CD5, PCSK9, KAT2B, GHSR, TRIB3, VIMP, INPP5K, SORBS1, CAPN10, ERRFI1, HDAC9, HDAC5, IRS2, MYO5A |
GO:0032870 | BP | cellular response to hormone stimulus | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus. |
SOCS2, SLIT2, FOS, JUN, ASNS, GHR, CYP11B1, JUNB, JUND, IGFBP2, CYP11B2, DUSP1, AVPR2, OXTR, STAT3, PGF, STAT5B, FOSB, UCP3, SIK1, NCOA2, NCOA1, IGFBP7, INPP5K, SIK2, ROBO2 |
GO:0032872 | BP | regulation of stress-activated MAPK cascade | Any process that modulates the frequency, rate or extent of signal transduction mediated by the stress-activated MAPK cascade. |
GSTP1, MAPK3, MAPK1, MAP2K2, MAP2K1, PRDX1, NBR1 |
GO:0032873 | BP | negative regulation of stress-activated MAPK cascade | Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the stress-activated MAPK cascade. |
MYC, GSTP1, IGBP1, FOXM1, FOXO1, PBK |
GO:0032874 | BP | positive regulation of stress-activated MAPK cascade | Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the stress-activated MAPK cascade. |
MID1, ARL6IP5, HMGCR, TGFB2, MAPK8IP2, PDCD10, TAOK3, TAOK2 |
GO:0032876 | BP | negative regulation of DNA endoreduplication | Any process that stops, prevents, or reduces the frequency, rate or extent of DNA endoreduplication. |
MRE11A, SMC1A, SMC3 |
GO:0032877 | BP | positive regulation of DNA endoreduplication | Any process that activates or increases the frequency, rate or extent of DNA endoreduplication. |
E2F8 |
GO:0032878 | BP | regulation of establishment or maintenance of cell polarity | Any process that modulates the frequency, rate or extent of the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns. |
TEK |
GO:0032880 | BP | regulation of protein localization | Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location. |
WASL, STX6, DNAJB6, RSL1D1, INS, PRNP, MAPK8, RAB9A, RACK1, PICALM, PTCH1, CAMK1, SEPT2, MMD, AAK1, RABGAP1L, BORA, TRIM22, CEP120, TEX15, CELSR3, B9D1 |
GO:0032886 | BP | regulation of microtubule-based process | Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the microtubule cytoskeleton. |
ERBB2, APC, GSK3B, KLHL42, MACF1 |
GO:0032897 | BP | negative regulation of viral transcription | Any process that stops, prevents, or reduces the frequency, rate or extent of viral transcription. |
TRIM13, ZFP36, IFITM3, TRIM14, TRIM62, TRIM8 |
GO:0032900 | BP | negative regulation of neurotrophin production | Any process that stops, prevents, or reduces the frequency, rate, or extent of production of a neurotrophin. |
ADORA1 |
GO:0032902 | BP | nerve growth factor production | The appearance of nerve growth factor (NGF) due to biosynthesis or secretion by cells in a neuron's target field, resulting in an increase in its intracellular or extracellular levels. |
FURIN, PCSK6 |
GO:0032909 | BP | regulation of transforming growth factor beta2 production | Any process that modulates the frequency, rate, or extent of production of transforming growth factor-beta2. |
TGFB2, SMAD3, SMAD4, HIF1A |
GO:0032911 | BP | negative regulation of transforming growth factor beta1 production | Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta1. |
FURIN, GATA6 |
GO:0032912 | BP | negative regulation of transforming growth factor beta2 production | Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta2. |
GATA6 |
GO:0032913 | BP | negative regulation of transforming growth factor beta3 production | Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta3. |
CD24 |
GO:0032914 | BP | positive regulation of transforming growth factor beta1 production | Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta1. |
THBS1, LUM, FOXP3 |
GO:0032916 | BP | positive regulation of transforming growth factor beta3 production | Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta3. |
CREB1, SMAD3 |
GO:0032918 | BP | spermidine acetylation | The modification of spermidine by addition of acetyl groups. |
SAT1, SAT2 |
GO:0032919 | BP | spermine acetylation | The modification of spermine by addition of acetyl groups. |
SAT1, SAT2 |
GO:0032920 | BP | putrescine acetylation | The modification of putrescine by addition of acetyl groups. |
SAT1, SAT2 |
GO:0032922 | BP | circadian regulation of gene expression | Any process that modulates the frequency, rate or extent of gene expression such that an expression pattern recurs with a regularity of approximately 24 hours. |
ARNTL, BHLHE40, OGT, PER1, USP2, NGFR, TOP1, DRD2, ATF4, NR1D1, KDM5A, RORA, AHR, PPP1CC, NAMPT, NRIP1, CSNK1D, CSNK1E, PPP1CA, PPP1CB, HNRNPU, RELB, ID2, CREM, GFPT1, PPARA, MTA1, HDAC1, NCOA2, ZFHX3, CRY1, CARTPT, HDAC2, PRKCDBP, NPAS2, RBM4B, MYBBP1A, LGR4, PPARGC1A, NOCT |
GO:0032924 | BP | activin receptor signaling pathway | A series of molecular signals initiated by the binding of an extracellular ligand to an activin receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. |
BMP10, INHBA, INHBB, ACVR2A, ACVR1B, TGFBR1, SMAD3, ACVR1, ACVR2B, BMPR2, SMAD2 |
GO:0032925 | BP | regulation of activin receptor signaling pathway | Any process that modulates the frequency, rate or extent of the activity of any activin receptor signaling pathway. |
SMAD7 |
GO:0032926 | BP | negative regulation of activin receptor signaling pathway | Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of any activin receptor signaling pathway. |
SKI, FST, SYNJ2BP, ACVR1, MAGI2, LEMD3 |
GO:0032927 | BP | positive regulation of activin receptor signaling pathway | Any process that activates or increases the frequency, rate or extent of the activity of any activin receptor signaling pathway. |
ACVR2A, FGF9, ACVR1B, SYNJ2BP, ACVR2B, ZC3H3 |
GO:0032928 | BP | regulation of superoxide anion generation | Any process that modulates the frequency, rate or extent of enzymatic generation of superoxide by a cell. |
SYK |
GO:0032929 | BP | negative regulation of superoxide anion generation | Any process that stops, prevents, or reduces the frequency, rate or extent of enzymatic generation of superoxide by a cell. |
AATF |
GO:0032930 | BP | positive regulation of superoxide anion generation | Any process that activates or increases the frequency, rate or extent of enzymatic generation of superoxide by a cell. |
EGFR, AGT, TGFB1, CRP, GSTP1, F2RL1, PRKCD |
GO:0032933 | BP | SREBP signaling pathway | A series of molecular signals from the endoplasmic reticulum to the nucleus generated as a consequence of decreased levels of one or more sterols (and in some yeast, changes in oxygen levels) and which proceeds through activation of a sterol response element binding transcription factor (SREBP) to result in up-regulation of target gene transcription. |
INSIG1, ERLIN2 |
GO:0032937 | CC | SREBP-SCAP-Insig complex | A protein complex formed by the association of sterol regulatory element binding protein (SREBP), SREBP-cleavage-activating protein (SCAP), and an Insig protein (Insig-1 or Insig-2) in the ER membrane. |
INSIG1, SREBF2 |
GO:0032940 | BP | secretion by cell | The controlled release of a substance by a cell. |
SERPINE2, FURIN, PCSK6, TYRO3, MERTK, CKLF |