| GO ID | Ontology | GO Term | Term Definition |
Proteins |
GO:0032469 | BP | endoplasmic reticulum calcium ion homeostasis | Any process involved in the maintenance of an internal steady state of calcium ions within the endoplasmic reticulum of a cell or between the endoplasmic reticulum and its surroundings. |
BCL2, ATP2A2, PSEN1, BAX, CAMK2D, ITPR1, GRINA, TMCO1 |
GO:0032470 | BP | positive regulation of endoplasmic reticulum calcium ion concentration | Any process that increases the concentration of calcium ions in the endoplasmic reticulum. |
ATP2A2 |
GO:0032471 | BP | negative regulation of endoplasmic reticulum calcium ion concentration | Any process that decreases the concentration of calcium ions in the endoplasmic reticulum. |
TGM2, BCAP31, RAP1GDS1, BAX |
GO:0032472 | BP | Golgi calcium ion transport | The directed movement of calcium ions (Ca2+) into, out of or within the Golgi apparatus. |
ATP2C1, TMEM165 |
GO:0032474 | BP | otolith morphogenesis | The process in which the anatomical structures of an otolith are generated and organized. |
LRIG3, LRIG1 |
GO:0032479 | BP | regulation of type I interferon production | Any process that modulates the frequency, rate, or extent of interferon type I production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families. |
UBC, RPS27A, UBA52 |
GO:0032480 | BP | negative regulation of type I interferon production | Any process that stops, prevents, or reduces the frequency, rate, or extent of type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families. |
ISG15, UBC, TNFAIP3, UBA7, RPS27A, UBA52, TRIM25, MAVS, TAX1BP1, NLRC5, ITCH, CYLD, RNF216, TBK1 |
GO:0032481 | BP | positive regulation of type I interferon production | Any process that activates or increases the frequency, rate, or extent of type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families. |
POLR1C, POLR3G, CRCP, CD14, IRF1, XRCC5, PLCG2, POLR2E, NFKB1, CTNNB1, SYK, MRE11A, IRAK1, POLR2K, POLR2L, PRKDC, RELA, EP300, IFI16, LRRFIP1, CREBBP, POLR3GL, POLR3C, POLR3F, DHX36, POLR3B, TBK1, PTPN22, POLR1D, POLR3K |
GO:0032482 | BP | Rab protein signal transduction | A series of molecular signals within the cell that are mediated by a member of the Rab family of proteins switching to a GTP-bound active state. |
GDI1 |
GO:0032483 | BP | regulation of Rab protein signal transduction | Any process that modulates the frequency, rate or extent of Rab protein signal transduction. |
DENND1A |
GO:0032485 | BP | regulation of Ral protein signal transduction | Any process that modulates the frequency, rate or extent of Ral protein signal transduction. |
RALGPS1, RALGPS2 |
GO:0032486 | BP | Rap protein signal transduction | A series of molecular signals within the cell that are mediated by a member of the Rap family of proteins switching to a GTP-bound active state. |
RAP2A, RAP2B, RAP1A, RAPGEF1, PLK2 |
GO:0032487 | BP | regulation of Rap protein signal transduction | Any process that modulates the frequency, rate or extent of Rap protein signal transduction. |
TIMP2, RDX, KIF14 |
GO:0032489 | BP | regulation of Cdc42 protein signal transduction | Any process that modulates the frequency, rate or extent of Cdc42 protein signal transduction. |
ABCA1, APOA1, APOE, APOC3 |
GO:0032490 | BP | detection of molecule of bacterial origin | The series of events in which a stimulus from a molecule of bacterial origin is received and converted into a molecular signal. |
C4A, C4B |
GO:0032494 | BP | response to peptidoglycan | Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptidoglycan stimulus. Peptidoglycan is a bacterial cell wall macromolecule. |
IL6, C5AR1, IRAK3 |
GO:0032495 | BP | response to muramyl dipeptide | Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muramyl dipeptide stimulus. Muramyl dipeptide is derived from peptidoglycan. |
TNFAIP3, NOTCH1, JAG1, RELA, MAPK14 |
GO:0032496 | BP | response to lipopolysaccharide | Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria. |
TLR4, TNFRSF11B, PTGES, TNFRSF10C, CYP27B1, JAK2, TNFRSF21, FOS, GNRH1, PENK, PPBP, PF4, SLPI, APOB, CYP1A1, S100A8, MPO, ALPL, EDN1, JUN, TH, DCN, NGFR, CXCL1, SPARC, CNP, MGST1, HSPD1, BCR, ALAD, SELE, PLCG2, IFNAR1, JUNB, JUND, VCAM1, CXCL2, CNR1, C5AR1, COMT, F2R, FAS, HMGB2, CD27, MAOB, TNFRSF8, IL12A, CASP1, CD6, S100A7, ADM, PTGS2, PTGER4, PCK1, LTBR, SNCA, CXCL5, PTGFR, PTGER2, NOTCH1, MAPKAPK2, SLC11A1, IRAK1, CASP9, TIRAP, ADAM17, CXCL6, TJP1, LOXL1, ABR, MTA1, HDAC1, CASP8, PCK2, HDAC2, TNFRSF25, PELI1, TRIB1, MGST2, CITED1, TRIM6, FOXP1, NOCT, PTPN22, IRAK3, TNFRSF11A, DUSP10 |
GO:0032497 | BP | detection of lipopolysaccharide | The series of events in which a lipopolysaccharide stimulus is received by a cell and converted into a molecular signal. Lipopolysaccharide is a major component of the cell wall of gram-negative bacteria. |
TLR4, SCARB1 |
GO:0032502 | BP | developmental process | A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition. |
COMT, NUDCD2, RNPC3, CITED4 |
GO:0032506 | BP | cytokinetic process | A cellular process that is involved in cytokinesis (the division of the cytoplasm of a cell and its separation into two daughter cells). |
SPAST |
GO:0032507 | BP | maintenance of protein location in cell | Any process in which a protein is maintained in a specific location within, or in the membrane of, a cell, and is prevented from moving elsewhere. |
CD4, CAV1, DBN1 |
GO:0032508 | BP | DNA duplex unwinding | The process in which interchain hydrogen bonds between two strands of DNA are broken or 'melted', generating a region of unpaired single strands. |
DDX3X, CHD1, CHD2, NBN, RECQL4, FSBP, ANXA1, XRCC5, MCM3, MCM5, RECQL, ATRX, MRE11A, DNA2, BLM, G3BP1, GINS1, CHD4, SETX, SUPV3L1, ASCC3, FBXO18, RAD50, GINS4, PIF1, CHD8, POT1, RUVBL2, GINS2, RUVBL1, RAD54B |
GO:0032510 | BP | endosome to lysosome transport via multivesicular body sorting pathway | The directed movement of substances from endosomes to lysosomes by a pathway in which molecules are sorted into multivesicular bodies, which then fuse with the lysosome. |
VPS4B, LYST |
GO:0032514 | BP | positive regulation of protein phosphatase type 2B activity | Any process that activates or increases the activity of the enzyme protein phosphatase type 2B. |
AKAP6 |
GO:0032515 | BP | negative regulation of phosphoprotein phosphatase activity | Any process that stops or reduces the activity of a phosphoprotein phosphatase. |
PPP1R11, PPP1R15A, PPP2R4, RGN |
GO:0032516 | BP | positive regulation of phosphoprotein phosphatase activity | Any process that activates or increases the activity of a phosphoprotein phosphatase. |
JAK2, PPP1R15A, HSP90AB1, PDGFRB, AGTR2, CALM2, PPP2R4, MAGI2 |
GO:0032525 | BP | somite rostral/caudal axis specification | The establishment, maintenance and elaboration of the rostro-caudal axis of a somite, prior to the morphological formation of a somite boundary. |
KDM6A, SMAD4, TMED2 |
GO:0032526 | BP | response to retinoic acid | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a retinoic acid stimulus. |
PTGES, DKK1, RBP4, PDGFRB, CTSH, IGF2R, IGFBP2, BMP6, DUSP1, TIE1, SREBF1, HSD17B2, PPARG, CLK2, ASCL1, PTCH1, NCOA1, IGFBP7, MICB, AQP3, DNAAF2 |
GO:0032527 | BP | protein exit from endoplasmic reticulum | The directed movement of proteins from the endoplasmic reticulum. |
RANGRF |
GO:0032528 | BP | microvillus organization | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microvillus, a thin cylindrical membrane-covered projection on the surface of a cell. |
PTPN11, GLDN |
GO:0032532 | BP | regulation of microvillus length | A process that modulates the length of a microvillus. |
EZR, PLS1, TWF2, CDHR2 |
GO:0032534 | BP | regulation of microvillus assembly | A process that modulates the formation of a microvillus. |
ATP8B1, PLD1, FSCN1 |
GO:0032535 | BP | regulation of cellular component size | A process that modulates the size of a cellular component. |
PTEN |
GO:0032541 | CC | cortical endoplasmic reticulum | A cortical network of highly dynamic tubules that are juxtaposed to the plasma membrane and undergo ring closure and tubule-branching movements. |
ASPH |
GO:0032542 | MF | sulfiredoxin activity | Catalysis of the reaction: peroxiredoxin-(S-hydroxy-S-oxocysteine) + ATP + 2 R-SH = peroxiredoxin-(S-hydroxycysteine) + ADP + phosphate + R-S-S-R. |
SESN2 |
GO:0032543 | BP | mitochondrial translation | The chemical reactions and pathways resulting in the formation of a protein in a mitochondrion. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the mitochondrion has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code. |
MRPS12, GATC, GATB, NDUFA7, HARS, MRPS21, MRPS34, MRPL23, MRPL51, PTCD3, MRPL57, QRSL1, MRPL47, MRPS18A, MRPL16, MRPS2, MRPS18B |
GO:0032545 | CC | CURI complex | A protein complex that is involved in the transcription of ribosomal genes. In Saccharomyces this complex consists of Ckb2p, Utp22p, Rrp7p and Ifh1p. |
RRP7A |
GO:0032549 | MF | ribonucleoside binding | Interacting selectively and non-covalently with a ribonucleoside, a compound consisting of a purine or pyrimidine nitrogenous base linked to ribose. |
POLR2B, POLR3B |
GO:0032556 | MF | pyrimidine deoxyribonucleotide binding | Interacting selectively and non-covalently with a pyrimidine deoxyribonucleotide, any compound consisting of a pyrimidine deoxyribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety. |
DCTPP1 |
GO:0032557 | MF | pyrimidine ribonucleotide binding | Interacting selectively and non-covalently with a pyrimidine ribonucleotide, any compound consisting of a pyrimidine ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety. |
UGP2 |
GO:0032564 | MF | dATP binding | Interacting selectively and non-covalently with dATP, deoxyadenosine triphosphate. |
HSP90AA1, HSP90AB1 |
GO:0032567 | MF | dGTP binding | Interacting selectively and non-covalently with dGTP, deoxyguanosine triphosphate. |
SAMHD1 |
GO:0032570 | BP | response to progesterone | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus. |
CLDN4, TLR2, FOS, TGFB1, TYMS, GPI, THBS1, CCL2, FOSL1, TSPO, OXTR, SREBF1, PTGER2, FOSB, TGFB2, CAV1, RELA, NR1H3, DSG2, NCOA1, BAD, TXNIP |
GO:0032571 | BP | response to vitamin K | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin K stimulus. |
BGLAP |
GO:0032580 | CC | Golgi cisterna membrane | The lipid bilayer surrounding any of the thin, flattened compartments that form the central portion of the Golgi complex. |
GOLGA8A, GPR89A, GOLIM4, ASAP2, B4GALT5, B4GALT4, GPR89B, B4GALT1, ST6GAL1, FUT1, FUT4, BCAP31, NUCB1, GOLGA2, GALNT2, GALNT1, FUT2, ST3GAL1, ST3GAL3, ST3GAL4, TMED2, ST3GAL2, CHSY3, CHSY1, HACE1, UXS1, CSGALNACT1, GOLGA1, YIPF5, APH1A, ST6GAL2, ARAP1, FUT8, INPP5E, B4GALT6, NAGPA, RAB21, TMED3, SAR1B |
GO:0032584 | CC | growth cone membrane | The portion of the plasma membrane surrounding a growth cone. |
GAP43, NECTIN1, EXOC4, LAMP5, EXOC7, TRPV2 |
GO:0032585 | CC | multivesicular body membrane | The lipid bilayer surrounding a multivesicular body. |
RAB27B, PMEL, RAB27A, ATP13A2, NDFIP2 |
GO:0032587 | CC | ruffle membrane | The portion of the plasma membrane surrounding a ruffle. |
MYO1C, SPRY2, PIP5K1C, PDE9A, ITGB3, ITGB1, ITGAV, HSP90AA1, ITGA5, TPM1, FGR, LCP1, EZR, NME1, ARF4, CFL1, APC, AKT2, NF2, TIRAP, RAC1, EEF1A1, ADAM17, TWF1, PTPRJ, EPS8, TIAM1, IFIT5, KANK1, PLEKHO1, THEM4, RASGRP2, FGD2, PDPN, C2CD5, WWC1, ARHGEF2, SH3YL1, SPATA13, DLC1, CIB1, AIF1L, FERMT1, INPP5K, PACSIN1, SPRY4, TRPV4, ARHGEF4, MYO6, MACF1, TLN1 |
GO:0032588 | CC | trans-Golgi network membrane | The lipid bilayer surrounding any of the compartments that make up the trans-Golgi network. |
SCAMP2, STX6, VAMP4, LGR5, RHOBTB3, HLA-DRA, HLA-DQA2, HLA-DQA1, HLA-DQB1, CD74, APP, CLTA, IGF2R, HLA-DRB4, HLA-DPA1, RAB9A, ARFIP1, AP1S2, AP1S1, HLA-DRB3, AP1B1, RAB31, COG2, VAMP3, HLA-DRB5, RABEPK, VPS52, MARCH1, USP6NL, LGR6, TMEM165, COG6, AP4S1, MMP24 |
GO:0032590 | CC | dendrite membrane | The portion of the plasma membrane surrounding a dendrite. |
ATF4, WLS, GABARAPL1, LAMP5 |
GO:0032591 | CC | dendritic spine membrane | The portion of the plasma membrane surrounding a dendritic spine. |
ATP2B1, TRPV1, GPER1 |
GO:0032592 | CC | integral component of mitochondrial membrane | The component of the mitochondrial membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
BID, MFF, ABCB10 |
GO:0032593 | CC | insulin-responsive compartment | A small membrane-bounded vesicle that releases its contents by exocytosis in response to insulin stimulation; the contents are enriched in GLUT4, IRAP and VAMP2. |
SLC2A4, RAB4B, DENND4C, MYO5A |
GO:0032596 | BP | protein transport into membrane raft | The directed movement of a protein into a membrane raft. Membrane rafts are small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. |
RFTN1, RFTN2 |
GO:0032597 | BP | B cell receptor transport into membrane raft | The directed movement of a B cell receptor into a membrane raft. |
CD24 |
GO:0032600 | BP | chemokine receptor transport out of membrane raft | The directed movement of a chemokine receptor out of a membrane raft. |
CD24 |
GO:0032602 | BP | chemokine production | The appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. |
S100A8, S100A9 |
GO:0032606 | BP | type I interferon production | The appearance of type I interferon due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families. |
TBK1 |
GO:0032607 | BP | interferon-alpha production | The appearance of interferon-alpha due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. |
AZI2 |
GO:0032609 | BP | interferon-gamma production | The appearance of interferon-gamma due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Interferon-gamma is also known as type II interferon. |
TLR4, AVPR2, LILRB1, AZI2 |
GO:0032611 | BP | interleukin-1 beta production | The appearance of interleukin-1 beta due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. |
IL1B, CASP1, MR1, PYCARD |
GO:0032613 | BP | interleukin-10 production | The appearance of interleukin-10 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. |
TLR2, CD46, PRKCD |
GO:0032615 | BP | interleukin-12 production | The appearance of interleukin-12 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. |
LEP, PRKCD |
GO:0032618 | BP | interleukin-15 production | The appearance of interleukin-15 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. |
TUSC2 |
GO:0032620 | BP | interleukin-17 production | The appearance of any member of the interleukin-17 family of cytokines due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. |
RFTN1, MR1 |
GO:0032623 | BP | interleukin-2 production | The appearance of interleukin-2 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. |
SLC11A1 |
GO:0032632 | BP | interleukin-3 production | The appearance of interleukin-3 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. |
SLC11A1 |
GO:0032635 | BP | interleukin-6 production | The appearance of interleukin-6 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. |
AZI2, ASH1L |
GO:0032640 | BP | tumor necrosis factor production | The appearance of tumor necrosis factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. |
AZI2 |
GO:0032642 | BP | regulation of chemokine production | Any process that modulates the frequency, rate, or extent of chemokine production. |
SNAI2 |
GO:0032648 | BP | regulation of interferon-beta production | Any process that modulates the frequency, rate, or extent of interferon-beta production. |
TRIM38, TIRAP, RNF216 |
GO:0032649 | BP | regulation of interferon-gamma production | Any process that modulates the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon. |
ISG15 |
GO:0032651 | BP | regulation of interleukin-1 beta production | Any process that modulates the frequency, rate, or extent of interleukin-1 beta production. |
F2R, S1PR3, SPHK1 |
GO:0032652 | BP | regulation of interleukin-1 production | Any process that modulates the frequency, rate, or extent of interleukin-1 production. |
ANXA1 |
GO:0032667 | BP | regulation of interleukin-23 production | Any process that modulates the frequency, rate, or extent of interleukin-23 production. |
TGFB1 |
GO:0032674 | BP | regulation of interleukin-5 production | Any process that modulates the frequency, rate, or extent of interleukin-5 production. |
IL5RA |
GO:0032675 | BP | regulation of interleukin-6 production | Any process that modulates the frequency, rate, or extent of interleukin-6 production. |
MAPKAPK2, AFAP1L2 |
GO:0032680 | BP | regulation of tumor necrosis factor production | Any process that modulates the frequency, rate, or extent of tumor necrosis factor production. |
ZFP36, MAPKAPK2, ANGPT1, FOXP1, TBC1D23 |
GO:0032688 | BP | negative regulation of interferon-beta production | Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-beta production. |
PPM1B, RELB, REL, PYCARD |
GO:0032689 | BP | negative regulation of interferon-gamma production | Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon. |
TLR4, IL33, PRNP, HMGB1, IL10, TNFSF4, IL1RL1, C1QBP, GAS6, LILRB1, PGLYRP2, FOXP3 |
GO:0032691 | BP | negative regulation of interleukin-1 beta production | Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-1 beta production. |
GSTP1, TNFAIP3, CHRNA7, GHSR, GHRL, ERRFI1 |
GO:0032692 | BP | negative regulation of interleukin-1 production | Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-1 production. |
IL10, NR1H4 |
GO:0032693 | BP | negative regulation of interleukin-10 production | Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-10 production. |
PRG2, JAK3, FOXP3 |
GO:0032695 | BP | negative regulation of interleukin-12 production | Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-12 production. |
THBS1, IL10, JAK3, C1QBP, PIBF1, IRAK3 |
GO:0032700 | BP | negative regulation of interleukin-17 production | Any process that stops, prevents, or reduces the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines. |
TLR4, TUSC2, TGFB1, PRNP, TNFSF4, IL12A, FOXP3 |
GO:0032701 | BP | negative regulation of interleukin-18 production | Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-18 production. |
IL10 |
GO:0032703 | BP | negative regulation of interleukin-2 production | Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-2 production. |
PRNP, TNFAIP3, HDAC7, NR1H4, FOXP3, VSIG4 |
GO:0032707 | BP | negative regulation of interleukin-23 production | Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-23 production. |
TLR4, RAC1 |
GO:0032713 | BP | negative regulation of interleukin-4 production | Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-4 production. |
CD83, NDFIP1, FOXP3 |
GO:0032714 | BP | negative regulation of interleukin-5 production | Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-5 production. |
FOXP3 |
GO:0032715 | BP | negative regulation of interleukin-6 production | Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-6 production. |
TLR4, SOCS5, TNF, ORM1, HGF, TNFAIP3, IL10, CHRNA7, CSK, GAS6, NR1H4, VIMP, FOXP3, KLF2, IRAK3 |
GO:0032717 | BP | negative regulation of interleukin-8 production | Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-8 production. |
IL10, OTUD7B |
GO:0032720 | BP | negative regulation of tumor necrosis factor production | Any process that stops, prevents, or reduces the frequency, rate, or extent of tumor necrosis factor production. |
TLR4, POMC, ORM1, GSTP1, TNFAIP3, IL10, TSPO, CHRNA7, HSF1, GAS6, GPNMB, TWIST1, ADIPOQ, VIMP, FOXP3, NFKBIL1, PTPN22, IRAK3 |
GO:0032722 | BP | positive regulation of chemokine production | Any process that activates or increases the frequency, rate, or extent of chemokine production. |
TLR4, TLR3, RIPK2, TLR2, TNF, IL6, IL6R, ADORA2B, ADAM17, HIF1A |
GO:0032725 | BP | positive regulation of granulocyte macrophage colony-stimulating factor production | Any process that activates or increases the frequency, rate, or extent of granulocyte macrophage colony-stimulating factor production. |
IL1B, PAEP, IL18 |
GO:0032727 | BP | positive regulation of interferon-alpha production | Any process that activates or increases the frequency, rate, or extent of interferon-alpha production. |
TLR4, RIPK2, HSPD1, MAVS, TBK1 |
GO:0032728 | BP | positive regulation of interferon-beta production | Any process that activates or increases the frequency, rate, or extent of interferon-beta production. |
TLR4, DDX3X, POLR3G, TLR3, RIPK2, TLR2, FLOT1, IRF1, IFNAR1, HMGB2, MAVS, POLR3C, POLR3F, ZBTB20, POLR3B, TBK1 |
GO:0032729 | BP | positive regulation of interferon-gamma production | Any process that activates or increases the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon. |
TLR4, RIPK2, SASH3, TNF, IL1B, CD14, HSPD1, IFNAR1, HLA-DPA1, BCL3, ZP3, TNFSF4, IL12A, WNT5A, IL12RB1, SLC11A1, PDE4D, FADD, IL18R1, IL18, PYCARD |
GO:0032731 | BP | positive regulation of interleukin-1 beta production | Any process that activates or increases the frequency, rate, or extent of interleukin-1 beta production. |
JAK2, HSPB1, SMAD3, IFI16 |