GO:0032269

BP

negative regulation of cellular protein metabolic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.

EDN1, MIF, NFKB1

GO:0032270

BP

positive regulation of cellular protein metabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.

KLF4, AGT, TGFB1, INS, INHBA, AGTR1, AKT1, NR1H2, NR1H3, ADIPOQ, UHRF1

GO:0032272

BP

negative regulation of protein polymerization

Any process that stops, prevents, or reduces the frequency, rate or extent of the process of creating protein polymers.

VDAC2

GO:0032273

BP

positive regulation of protein polymerization

Any process that activates or increases the frequency, rate or extent of the process of creating protein polymers.

TPPP

GO:0032275

BP

luteinizing hormone secretion

The regulated release of luteinizing hormone, a gonadotropic glycoprotein hormone secreted by the anterior pituitary.

TMF1

GO:0032279

CC

asymmetric synapse

A type of synapse occurring between an axon and a dendritic spine or dendritic shaft. Asymmetric synapses, the most abundant synapse type in the central nervous system, involve axons that contain predominantly spherical vesicles and contain a thickened postsynaptic density. Most or all synapses of this type are excitatory.

CHRM2, CHRM3, ADORA1, ARFGEF2

GO:0032280

CC

symmetric synapse

A synapse that lacks an electron dense postsynaptic specialization. In vertebtrates, these occur primarily on dendrite shafts and neuronal cell bodies and involve persynapses containing clusters of predominantly flattened or elongated vesicles and are typcially inhibitory.

PENK, CHRM2, ARFGEF2

GO:0032281

CC

AMPA glutamate receptor complex

An assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. The AMPA receptors mediate fast synaptic transmission in the CNS and are composed of subunits GluR1-4, products from separate genes. These subunits have an extracellular N-terminus and an intracellular C-terminus.

GRIA4, DLG4, SHISA6, ABHD12, CACNG8, ABHD6

GO:0032286

BP

central nervous system myelin maintenance

The process in which the structure and material content of mature central nervous system myelin is kept in a functional state.

CLU, PTEN, FA2H, MYRF

GO:0032287

BP

peripheral nervous system myelin maintenance

The process in which the structure and material content of mature peripheral nervous system myelin is kept in a functional state.

AKT1, AKT2, FA2H, MPP5, SH3TC2, NDRG1

GO:0032288

BP

myelin assembly

The process in which the wraps of cell membrane that constitute myelin are laid down around an axon in the central or peripheral nervous system.

GPC1, ILK, MTMR2, MPP5, PIKFYVE

GO:0032289

BP

central nervous system myelin formation

The process in which the wraps of cell membrane that constitute myelin are laid down around an axon by an oligodendrocyte in the central nervous system.

TLR2, ERCC2, TENM4

GO:0032290

BP

peripheral nervous system myelin formation

The process in which the wraps of cell membrane that constitute myelin are laid down around an axon by an oligodendrocyte in the peripheral nervous system.

DICER1

GO:0032298

BP

positive regulation of DNA-dependent DNA replication initiation

Any process that activates or increases the frequency, rate or extent of initiation of DNA-dependent DNA replication.

CDK2

GO:0032299

CC

ribonuclease H2 complex

A protein complex that possesses ribonuclease H activity, in which the catalytic subunit is a member of the RNase H2 (or HII) class. For example, in Saccharomyces the complex contains Rnh201p, Rnh202p and Rnh203p.

RNASEH2A, RNASEH2B

GO:0032300

CC

mismatch repair complex

Any complex formed of proteins that act in mismatch repair.

MLH3

GO:0032301

CC

MutSalpha complex

A heterodimer involved in the recognition and repair of base-base and small insertion/deletion mismatches. In human the complex consists of two subunits, MSH2 and MSH6.

MSH2, MSH6

GO:0032302

CC

MutSbeta complex

A heterodimer involved in binding to and correcting insertion/deletion mutations. In human the complex consists of two subunits, MSH2 and MSH3.

MSH3, MSH2

GO:0032304

BP

negative regulation of icosanoid secretion

Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of an icosanoid from a cell.

AGTR2

GO:0032308

BP

positive regulation of prostaglandin secretion

Any process that activates or increases the frequency, rate or extent of the regulated release of a prostaglandin from a cell.

IL1B, EDN1, MAP2K6, P2RX4

GO:0032310

BP

prostaglandin secretion

The regulated release of a prostaglandin, any of a group of biologically active metabolites which contain a cyclopentane ring, from a cell or a tissue.

ABCC4, LEP

GO:0032311

CC

angiogenin-PRI complex

A stable heterodimer of angiogenin and placental ribonuclease inhibitor; interaction between angiogenin and PRI prevents angiogenin binding to its receptor to stimulate angiogenesis.

ANG, RNH1

GO:0032324

BP

molybdopterin cofactor biosynthetic process

The chemical reactions and pathways resulting in the formation of the molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands.

MOCOS, GPHN

GO:0032330

BP

regulation of chondrocyte differentiation

Any process that modulates the frequency, rate or extent of chondrocyte differentiation.

SHOX2, MAF, CTGF, GLG1, LNP, TRPS1

GO:0032331

BP

negative regulation of chondrocyte differentiation

Any process that stops, prevents, or reduces the frequency, rate or extent of chondrocyte differentiation.

SNAI2, GREM1, GLI2, PTHLH, BMP4, CTNNB1, TGFBR1, GDF5, SOX9, ADAMTS12, EFEMP1, ADAMTS7

GO:0032332

BP

positive regulation of chondrocyte differentiation

Any process that activates or increases the frequency, rate or extent of chondrocyte differentiation.

FGF18, GLI3, BMP6, SOX6, GDF5, SOX9, SMAD3, RELA, ZBTB16, RUNX2, LOXL2

GO:0032342

BP

aldosterone biosynthetic process

The chemical reactions and pathways resulting in the formation of aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance.

CYP11B1, CYP11B2

GO:0032348

BP

negative regulation of aldosterone biosynthetic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone.

BMP2, DKK3

GO:0032349

BP

positive regulation of aldosterone biosynthetic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone.

BMP6

GO:0032350

BP

regulation of hormone metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving any hormone.

TCF7L2

GO:0032354

BP

response to follicle-stimulating hormone

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a follicle-stimulating hormone stimulus.

ASNS, SRD5A1, SRD5A2, TGFBR3, PAPPA

GO:0032355

BP

response to estradiol

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen.

SOCS2, DHH, ALDH1A2, MBD4, MBD3, ASS1, CST3, TGFB1, PENK, GH1, CD4, COL1A1, CRYAB, ESR1, ANXA1, GPI, TH, GSTP1, PDGFRB, TFPI, ESRRA, PCNA, EEF2, ETS1, AREG, NQO1, IGFBP2, PAM, NR2F2, CALR, DUSP1, CTGF, SLC6A1, OXTR, CTNNB1, PTGS2, STAT3, OPRL1, LEP, ADCYAP1R1, PTGFR, CDKN1B, MMP15, STAT5B, CASP9, BID, PTEN, STRN3, PTCH1, KCNJ11, CASP8, POSTN, NCOA1, EZH2, BAD, TXNIP, WFDC1, DNMT3B

GO:0032357

MF

oxidized purine DNA binding

Interacting selectively and non-covalently with oxidized purine residues in DNA.

MSH2, MSH6

GO:0032364

BP

oxygen homeostasis

A homeostatic process involved in the maintenance of an internal steady state of oxygen within an organism or cell.

SOD2, HIF1A

GO:0032366

BP

intracellular sterol transport

The directed movement of sterols within cells.

NPC2

GO:0032367

BP

intracellular cholesterol transport

The directed movement of cholesterol, cholest-5-en-3-beta-ol, within cells.

ABCA1, STAR, NPC2, STARD4

GO:0032368

BP

regulation of lipid transport

Any process that modulates the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

PARK2

GO:0032369

BP

negative regulation of lipid transport

Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

ITGB3, ITGAV, NR1H2, NR1H3

GO:0032374

BP

regulation of cholesterol transport

Any process that modulates the frequency, rate or extent of the directed movement of cholesterol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

APOC1, TSPO

GO:0032375

BP

negative regulation of cholesterol transport

Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of cholesterol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

APOA2, APOC1, NFKB1

GO:0032376

BP

positive regulation of cholesterol transport

Any process that activates or increases the frequency, rate or extent of the directed movement of cholesterol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

NR1H2, NR1H3, LIPG

GO:0032385

BP

positive regulation of intracellular cholesterol transport

Any process that activates or increases the frequency, rate or extent of the directed movement of cholesterol within cells.

SCP2

GO:0032386

BP

regulation of intracellular transport

Any process that modulates the frequency, rate or extent of the directed movement of substances within cells.

WWC1

GO:0032387

BP

negative regulation of intracellular transport

Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances within cells.

CRYAB, MAPT, MAP1B

GO:0032388

BP

positive regulation of intracellular transport

Any process that activates or increases the frequency, rate or extent of the directed movement of substances within cells.

CAPN10

GO:0032389

CC

MutLalpha complex

A heterodimer involved in the recognition of base-base and small insertion/deletion mismatches. In human the complex consists of two subunits, MLH1 and PMS2.

MLH1, PMS1

GO:0032391

CC

photoreceptor connecting cilium

A nonmotile primary cilium that has a 9+0 microtubule array and forms the portion of the axoneme traversing the boundary between the photoreceptor inner and outer segments.

NPHP1, C21orf2, MAK, SEPT2, FAM161A, KIFAP3, IFT122, SPATA7

GO:0032392

BP

DNA geometric change

The process in which a transformation is induced in the geometry of a DNA double helix, resulting in a change in twist, writhe, or both, but with no change in linking number. Includes the unwinding of double-stranded DNA by helicases.

HMGB3, HMGB1, HMGB2, MTERF1

GO:0032393

MF

MHC class I receptor activity

Combining with an MHC class I protein complex to initiate a change in cellular activity. Class I here refers to classical class I molecules.

LILRB1, MR1

GO:0032395

MF

MHC class II receptor activity

Combining with an MHC class II protein complex and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.

HLA-DRA, HLA-DQA2, HLA-DQA1, HLA-DQB1, HLA-DOB, HLA-DPA1, HLA-DRB3, KRT17

GO:0032398

CC

MHC class Ib protein complex

A transmembrane protein complex composed of a MHC class Ib alpha chain and, in most cases, an invariant beta2-microglobin chain, and with or without a bound peptide or lipid antigen. Class Ib here refers to non-classical class I molecules, such as those of the CD1 or HLA-E gene families.

HLA-E

GO:0032400

BP

melanosome localization

Any process in which a melanosome is transported to, and/or maintained in, a specific location within the cell.

RAB27A

GO:0032401

BP

establishment of melanosome localization

The directed movement of a melanosome to a specific location.

SHROOM2

GO:0032402

BP

melanosome transport

The directed movement of melanosomes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

RAB27B, RAB27A, RAB11A, RAB1A, DCTN2, DCTN1, RAB11B, BLOC1S3, BBS7, BBS2, MKKS, BLOC1S6, MYO5A

GO:0032403

MF

protein complex binding

Interacting selectively and non-covalently with any protein complex (a complex of two or more proteins that may include other nonprotein molecules).

APBB1, NDUFA4, KRIT1, ITGB1BP1, FYB, CFLAR, ULK1, TULP3, CRTAP, MYC, NRAS, KRAS, NR3C1, ITGB2, ITGB1, KRT8, C8G, TUBB, KRT19, RRAS, PTPRF, HSPD1, THRA, CDK4, HCLS1, EPCAM, ITGA2, ATF1, UQCRC2, FBLN1, PPIB, NFYB, UQCRC1, YWHAB, FBN1, PPP1CC, SREBF1, CDKN1A, CAPG, MTHFR, NSF, CDKN1B, IQGAP1, UQCRFS1, TMED10, RANBP2, BCAP31, KIF11, IST1, EPHB1, ATP6V0D1, PPP1CA, RAP1A, GNB1, RBX1, GNB2, AP2B1, IGBP1, DLG4, SLC25A3, SPTBN1, RELA, KHDRBS1, PPARA, TWF1, STRN3, FADD, PDCL, MAPK8IP2, RIPK1, CUL2, PTCH1, DAG1, GIT2, COG2, CASP8, TCEB1, NR0B2, TRADD, TSN, TAB1, NCOA1, LRRC16A, CYFIP1, SLF2, ABI1, FLCN, KAT6B, KAT2B, UFD1L, TXN2, SLF1, TAPBPL, NDEL1, STRN4, RAD18, ABI2, PLK2, CRIPT, GIT1, WASF2

GO:0032405

MF

MutLalpha complex binding

Interacting selectively and non-covalently with the mismatch repair complex MutLalpha.

PCNA, MSH2, MSH6

GO:0032407

MF

MutSalpha complex binding

Interacting selectively and non-covalently with the mismatch repair complex MutSalpha.

MLH1, MUTYH

GO:0032410

BP

negative regulation of transporter activity

Any process that stops or reduces the activity of a transporter.

WWP2, SNCA, NDFIP1, NDFIP2, CTTNBP2NL

GO:0032411

BP

positive regulation of transporter activity

Any process that activates or increases the activity of a transporter.

SYNGR3, PON1, SGK3

GO:0032412

BP

regulation of ion transmembrane transporter activity

Any process that modulates the activity of an ion transporter.

AHCYL1

GO:0032414

BP

positive regulation of ion transmembrane transporter activity

Any process that activates or increases the activity of an ion transporter.

WNK3, WNK1, TRPC6

GO:0032417

BP

positive regulation of sodium:proton antiporter activity

Any process that activates or increases the activity of a sodium:hydrogen antiporter, which catalyzes the reaction: Na+(out) + H+(in) = Na+(in) + H+(out).

ACTN4, CHP1

GO:0032418

BP

lysosome localization

Any process in which a lysosome is transported to, and/or maintained in, a specific location.

SNAPIN, BLOC1S1, LAMTOR1, LOH12CR1, BORCS6, RAB34, TMEM106B, ARL8B, HDAC6

GO:0032419

CC

extrinsic component of lysosome membrane

The component of an lysosome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.

RAB7A

GO:0032420

CC

stereocilium

An actin-based protrusion from the apical surface of auditory and vestibular hair cells and of neuromast cells. These protrusions are supported by a bundle of cross-linked actin filaments (an actin cable), oriented such that the plus (barbed) ends are at the tip of the protrusion, capped by a tip complex which bridges to the plasma. Bundles of stereocilia act as mechanosensory organelles.

ATP8B1, RDX, MPP1, EPS8, TWF2, GPR98, BBS2, CLIC5

GO:0032422

MF

purine-rich negative regulatory element binding

Interacting selectively and non-covalently with a 30-bp purine-rich negative regulatory element; the best characterized such element is found in the first intronic region of the rat cardiac alpha-myosin heavy chain gene, and contains two palindromic high-affinity Ets-binding sites (CTTCCCTGGAAG). The presence of this element restricts expression of the gene containing it to cardiac myocytes.

ELK3, PURA

GO:0032425

BP

positive regulation of mismatch repair

Any process that activates or increases the frequency, rate or extent of mismatch repair.

HMGB1

GO:0032427

MF

GBD domain binding

Interacting selectively and non-covalently with the GTPase protein binding domain (GDB) domain of a protein. The GBD is a short motif, including a minimum region of 16 amino acids, identified in proteins that bind to small GTPases such as Cdc42 and Rac.

RHOQ

GO:0032428

MF

beta-N-acetylgalactosaminidase activity

Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-galactosamine residues in N-acetyl-beta-D-galactosaminides.

GM2A

GO:0032429

BP

regulation of phospholipase A2 activity

Any process that modulates the activity of the enzyme phospholipase A2.

PPT1

GO:0032430

BP

positive regulation of phospholipase A2 activity

Any process that activates or increases the activity of the enzyme phospholipase A2.

AGTR1

GO:0032431

BP

activation of phospholipase A2 activity

Any process that initiates the activity of the inactive enzyme phospholipase A2.

ANG

GO:0032432

CC

actin filament bundle

An assembly of actin filaments that are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness.

CRYAB, LCP1, PLS1, FAM101A, FAM101B

GO:0032433

CC

filopodium tip

The end of a filopodium distal to the body of the cell.

EPHB1, FMR1, NLGN1, CIB1, TTYH1, MYO10, MYO5A

GO:0032434

BP

regulation of proteasomal ubiquitin-dependent protein catabolic process

Any process that modulates the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.

RAD23A, RAD23B, GNA12, COMMD1, GLMN, DDA1, UBQLN4

GO:0032435

BP

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.

SDCBP, N4BP1, HSP90AB1, FHIT, MTM1, HFE, CCAR2, SMARCC1, PBK, WAC, BAG5

GO:0032436

BP

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

Any process that activates or increases the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.

AURKA, SMAD7, PARK2, SOCS5, PSMD10, IL33, CLU, AKT1, GCLC, CSNK1A1, CSNK1D, CSNK1E, PSEN1, GSK3B, RNF144A, PLK1, VCP, SUMO2, RACK1, DAB2, MDM2, UBE2V2, RNF19B, RNF144B, BBS7, SIRT2, FBXO22, TRIB2, PRICKLE1, TRIB3, TRIB1, RNF19A, PLK2, RNF14, STUB1, ARIH1, RNF114, NUB1

GO:0032437

CC

cuticular plate

A dense network of actin filaments found beneath the apical cell surface of hair cells, and into which stereocilia are inserted.

SPTBN1

GO:0032438

BP

melanosome organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a melanosome. A melanosome is a tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored.

AP3D1, RAB29, SNAPIN, PMEL, BLOC1S1, SHROOM2, BLOC1S3, LYST, BLOC1S6

GO:0032439

BP

endosome localization

Any process in which endosomes are transported to, and/or maintained in, a specific location within the cell.

LAMTOR1, ANKFY1, MYO5B

GO:0032440

MF

2-alkenal reductase [NAD(P)] activity

Catalysis of the reaction: n-alkanal + NAD(P)+ = alk-2-enal + NAD(P)H + H+.

PTGR1

GO:0032444

CC

activin responsive factor complex

A transcriptionally active complex that binds to an activin response element (ARE) in the promoter of target genes, and is composed of two SMAD2 proteins, one SMAD4 protein and a Forkhead activin signal transducer (FAST) transcription factor.

SMAD4, SMAD2

GO:0032446

BP

protein modification by small protein conjugation

A protein modification process in which one or more groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are covalently attached to a target protein.

UBD, ATG10

GO:0032448

MF

DNA hairpin binding

Interacting selectively and non-covalently with DNA containing a hairpin. A hairpin structure forms when a DNA strand folds back on itself and intrachain base pairing occurs between inverted repeat sequences.

NR0B1

GO:0032449

CC

CBM complex

A protein complex comprising Carma1, Bcl10 and MALT1; plays a role in signal transduction during NF-kappaB activation.

BCL10, CARD10

GO:0032450

MF

maltose alpha-glucosidase activity

Catalysis of the reaction: alpha-maltose + H2O = 2 alpha-D-glucose.

MGAM, GAA

GO:0032451

MF

demethylase activity

Catalysis of the removal of a methyl group from a substrate.

KDM1A, CYP1A1

GO:0032452

MF

histone demethylase activity

Catalysis of the removal of a methyl group from a histone.

UTY, KDM6A, KDM1A, KDM4B, KDM5A, ARID5B, JMJD6, KDM7A, KDM5B, KDM2A

GO:0032453

MF

histone demethylase activity (H3-K4 specific)

Catalysis of the removal of a methyl group from lysine at position 4 of the histone H3 protein.

KDM1A, KDM5B

GO:0032454

MF

histone demethylase activity (H3-K9 specific)

Catalysis of the reaction: histone H3 N6-methyl-L-lysine (position 9) + alpha-ketoglutarate + O2 = succinate + CO2 + formaldehyde + lysine. This reaction is the removal of a methyl group from lysine at position 9 of the histone H3 protein.

KDM1A, JMJD1C, KDM7A

GO:0032455

BP

nerve growth factor processing

The generation of a mature nerve growth factor (NGF) by proteolysis of a precursor.

NGF, FURIN, PCSK6, PCSK5

GO:0032456

BP

endocytic recycling

The directed movement of membrane-bounded vesicles from recycling endosomes back to the plasma membrane where they are recycled for further rounds of transport.

STX6, RAB11FIP3, SNX4, EPS15, VPS52, DENND1A, EHD4, EPG5, EHD3

GO:0032460

BP

negative regulation of protein oligomerization

Any process that stops, prevents, or reduces the frequency, rate or extent of protein oligomerization.

INS, SORL1

GO:0032461

BP

positive regulation of protein oligomerization

Any process that activates or increases the frequency, rate or extent of protein oligomerization.

MMP1, TP53, CCK, IDE, BID, BAX, PMAIP1, TRABD2A, SH3GLB1, SNX9

GO:0032463

BP

negative regulation of protein homooligomerization

Any process that stops, prevents, or reduces the frequency, rate or extent of protein homooligomerization.

CLU

GO:0032464

BP

positive regulation of protein homooligomerization

Any process that activates or increases the frequency, rate or extent of protein homooligomerization.

BCL2L11, FAS, BID, RACK1, MIEF2

GO:0032465

BP

regulation of cytokinesis

Any process that modulates the frequency, rate or extent of the division of the cytoplasm of a cell and its separation into two daughter cells.

AURKA, PRPF40A, BRCA2, CALM2, PIK3C3, FLCN, PIK3R4, GIT1, SH3GLB1

GO:0032466

BP

negative regulation of cytokinesis

Any process that stops, prevents, or reduces the frequency, rate or extent of the division of the cytoplasm of a cell, and its separation into two daughter cells.

E2F8, TEX14, AURKB, ZFYVE19

GO:0032467

BP

positive regulation of cytokinesis

Any process that activates or increases the frequency, rate or extent of the division of the cytoplasm of a cell, and its separation into two daughter cells.

DRD2, CDC25B, SSTR5, CDC42, RHOA, KIF23, CUL3, KIF14, PKN2, CSPP1, CENPV, AURKB, KIF20B, PKP4, CDC6, RACGAP1, ECT2, SPAST

GO:0032468

BP

Golgi calcium ion homeostasis

Any process involved in the maintenance of an internal steady state of calcium ions within the Golgi apparatus of a cell or between the Golgi and its surroundings.

ATP2C1