GO:0030515

MF

snoRNA binding

Interacting selectively and non-covalently with small nucleolar RNA.

NOP56, NUDT7, NUDT1, SNU13, TBL3, NUDT16, NUFIP1, NUDT5, WDR3

GO:0030516

BP

regulation of axon extension

Any process that modulates the rate, direction or extent of axon extension.

APOE, CTTN, DPYSL2, TTL, WDR36, NRCAM, OLFM1, RAB21

GO:0030517

BP

negative regulation of axon extension

Any process that stops, prevents, or reduces the frequency, rate or extent of axon outgrowth.

IFRD1, MT3, CDK5, RTN4, RNF6

GO:0030518

BP

intracellular steroid hormone receptor signaling pathway

A series of molecular signals generated as a consequence of a intracellular steroid hormone receptor binding to one of its physiological ligands.

PLPP1, MED14, ESR1, MED12, MED30, GPER1, MED4, MED17, THRAP3, MED16

GO:0030520

BP

intracellular estrogen receptor signaling pathway

Any series of molecular signals generated as a consequence of an intracellular estrogen receptor binding to one of its physiological ligands. The pathway begins with receptor-ligand binding, and ends with regulation of a downstream cellular process (e.g. transcription).

ARID1A, RBFOX2, TADA3, ESR1, CARM1, PPARGC1B, DDX54, ESR2

GO:0030521

BP

androgen receptor signaling pathway

Any series of molecular signals generated as a consequence of an androgen binding to its receptor.

PLPP1, ARID1A, TGFB1I1, MED14, RB1, AR, DNAJA1, CTNNB1, BRCA1, NRIP1, CDK7, FKBP4, NCOA4, NCOA1, MED12, PMEPA1, MED30, MED4, MED17, PPARGC1A, RNF14, THRAP3, MED16, NCOA3

GO:0030522

BP

intracellular receptor signaling pathway

Any series of molecular signals initiated by a ligand binding to an receptor located within a cell.

NR5A2, AR, NR2F1, THRA, ESRRA, NR1D1, NR4A1, NR2F2, ARNT, RORA, AHR, STAT3, NR4A2, NR0B1, PPARD, NOTCH2, PPARA, NR1H3, NR1D2, NCOA2, NCOA1, GLMP, NR4A3, DCBLD2, NR1H4, NCOA3

GO:0030529

CC

intracellular ribonucleoprotein complex

An intracellular macromolecular complex containing both protein and RNA molecules.

XPO1, HNRNPR, ACTN4, SYNCRIP, GAPDH, RPLP0, SSB, NPM1, EPRS, HNRNPA1, TROVE2, EEF2, HNRNPL, DDX5, RPL7, HNRNPA2B1, ZFP36, RPL22, RPL4, NUP62, RBMX, BRCA1, RPL13A, LRPPRC, RPL5, RPS9, RPS5, CSNK1A1, CSNK1E, GSK3B, HNRNPA3, HNRNPH2, PCBP4, ACTB, RPS3A, RPL27, RPS7, RPS8, RPS6, YBX1, HNRNPU, FMR1, ZFP36L1, NCBP1, ILF2, ILF3, G3BP1, NFATC2, HNRNPD, BOP1, SLBP, PCBP1, LARP7, JMJD6, PABPN1, MRPL41, DYRK2, SECISBP2L, TEFM, SECISBP2, HNRNPAB, TEP1, LARP6, HNRNPUL1, SLIRP, APOBEC3G, SRA1, PUF60, AGO2, G3BP2, PA2G4

GO:0030532

CC

small nuclear ribonucleoprotein complex

A complex composed of RNA of the small nuclear RNA (snRNA) class and protein, found in the nucleus of a eukaryotic cell. These are typically named after the snRNA(s) they contain, e.g. U1 snRNP or U4/U6 snRNP. Many, but not all, of these complexes are involved in splicing of nuclear mRNAs.

SNRPA1, SNRPB, GEMIN4, SNRPF, LSM6, SNRPD1, SNRPD2, SNRPD3, SNRPN

GO:0030534

BP

adult behavior

Behavior in a fully developed and mature organism.

PCDH17, MAFG, SLC1A2, PTEN, NLGN4X, NR4A3, BBS2, NRXN1

GO:0030539

BP

male genitalia development

The process whose specific outcome is the progression of the male genitalia over time, from its formation to the mature structure.

SRD5A1, WT1, BMP6, LHCGR, SRD5A2, CTNNB1, DHCR24, LGR4, TEX15

GO:0030540

BP

female genitalia development

The process whose specific outcome is the progression of the female genitalia over time, from formation to the mature structure.

SRD5A1, SRD5A2, CHD7

GO:0030544

MF

Hsp70 protein binding

Interacting selectively and non-covalently with Hsp70 proteins, any of a group of heat shock proteins around 70kDa in size.

GPR37, PARK2, ERN1, CDK1, CREB1, DNAJB1, DNAJA1, STIP1, NUP62, CDKN1B, MVD, PPID, C11orf73, DNAJC10, METTL21A, PACRG, HDAC8, IQCG, STUB1

GO:0030546

MF

receptor activator activity

The function of interacting (directly or indirectly) with receptors such that the proportion of receptors in the active form is increased.

IGF2, ANXA2, PPARGC1B

GO:0030547

MF

receptor inhibitor activity

The function of interacting (directly or indirectly) with receptors such that the proportion of receptors in the active form is decreased.

PCSK9

GO:0030549

MF

acetylcholine receptor activator activity

Interacting (directly or indirectly) with acetylcholine receptors such that the proportion of receptors in the active form is increased.

CDK5

GO:0030550

MF

acetylcholine receptor inhibitor activity

Interacting (directly or indirectly) with acetylcholine receptors such that the proportion of receptors in the active form is decreased.

LYPD1

GO:0030551

MF

cyclic nucleotide binding

Interacting selectively and non-covalently with a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue.

CNP

GO:0030552

MF

cAMP binding

Interacting selectively and non-covalently with cAMP, the nucleotide cyclic AMP (adenosine 3',5'-cyclophosphate).

PRKAR1A, PRKAR2A, PRKAR2B, PDE4D, PDE3A, BVES, RAPGEF4, POPDC3

GO:0030553

MF

cGMP binding

Interacting selectively and non-covalently with cGMP, the nucleotide cyclic GMP (guanosine 3',5'-cyclophosphate).

PDE5A, CNGA1

GO:0030554

MF

adenyl nucleotide binding

Interacting selectively and non-covalently with adenyl nucleotides, any compound consisting of adenosine esterified with (ortho)phosphate.

AHCY

GO:0030573

BP

bile acid catabolic process

The chemical reactions and pathways resulting in the breakdown of bile acids, any of a group of steroid carboxylic acids occurring in bile.

SULT2A1

GO:0030574

BP

collagen catabolic process

The proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix, usually carried out by proteases secreted by nearby cells.

COL1A1, COL3A1, MMP1, COL5A2, CTSD, CTSL, CTSB, COL1A2, MMP2, COL4A2, MMP10, FURIN, COL11A1, COL6A1, COL6A2, COL6A3, COL11A2, MMP9, COL5A1, MMP8, MMP11, COL8A2, CTSS, COL5A3, COL15A1, COL18A1, CTSK, MMP14, MMP15, MMP16, COL4A3, COL10A1, COL4A6, COL13A1, PHYKPL, MMP19, COL12A1, MMP26

GO:0030576

BP

Cajal body organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of Cajal bodies, nuclear bodies that appear ultrastructurally as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter and are enriched in ribonucleoproteins, and certain general RNA polymerase II transcription factors.

ZPR1

GO:0030578

BP

PML body organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of PML bodies, a class of nuclear body; they react against SP100 auto-antibodies (PML = promyelocytic leukemia).

ETS1, HIPK2

GO:0030579

BP

ubiquitin-dependent SMAD protein catabolic process

The chemical reactions and pathways resulting in the breakdown of SMAD signaling proteins by ubiquitination and targeting to the proteasome.

TGFB1I1, RNF111, SMURF2, STUB1

GO:0030593

BP

neutrophil chemotaxis

The directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.

PIK3CD, PIP5K1C, IL1B, PPBP, ITGB2, S100A8, S100A9, SAA1, CXCL8, CCL3, CCL4, CCL2, CCL5, VAV1, LGALS3, EDN2, C5AR1, CXCR2, SYK, PIK3CG, TGFB2, CXADR, CCL20, CCL8, PDE4D, ITGA9, GBF1, CSF3R, TREM1, CKLF, VAV3

GO:0030594

MF

neurotransmitter receptor activity

Combining with a neurotransmitter and transmitting the signal to initiate a change in cell activity.

HTR2C, HTR7, HTR2B

GO:0030595

BP

leukocyte chemotaxis

The movement of a leukocyte in response to an external stimulus.

PF4, S1PR1, IL10, CORO1A, GPR183, LYST, SBDS

GO:0030616

MF

transforming growth factor beta receptor, common-partner cytoplasmic mediator activity

A TGF-beta cytoplasmic mediator that forms a complex with a phosphorylated pathway-specific mediator. The heterocomplex translocates to the nucleus to regulate transcription.

SMAD4

GO:0030617

MF

transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity

A TGF-beta cytoplasmic mediator that inhibits the signaling function of common-partner and pathway-specific mediators.

SMAD7, SMAD6

GO:0030618

MF

transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity

A TGF-beta cytoplasmic mediator that is phosphorylated by a TGFbeta receptor and complexes with a common-partner mediator. The- heterocomplex translocates to the nucleus to regulate transcription.

SMAD9, SMAD3, SMAD2, SMAD1, SMAD5

GO:0030619

MF

U1 snRNA binding

Interacting selectively and non-covalently with the U1 small nuclear RNA (U1 snRNA).

SNRPA, ISG20

GO:0030620

MF

U2 snRNA binding

Interacting selectively and non-covalently with the U2 small nuclear RNA (U2 snRNA).

SNRPA1, TROVE2, SNRPB, SNRPD3, ISG20

GO:0030621

MF

U4 snRNA binding

Interacting selectively and non-covalently with the U4 small nuclear RNA (U4 snRNA).

SNU13, SART3, PRPF31

GO:0030622

MF

U4atac snRNA binding

Interacting selectively and non-covalently with the U4atac small nuclear RNA (U4atac snRNA).

SNU13, PRPF31

GO:0030624

MF

U6atac snRNA binding

Interacting selectively and non-covalently with the U6atac small nuclear RNA (U6atac snRNA).

SART3

GO:0030626

MF

U12 snRNA binding

Interacting selectively and non-covalently with the U12 small nuclear RNA (U12 snRNA).

RNPC3

GO:0030627

MF

pre-mRNA 5'-splice site binding

Interacting selectively and non-covalently with the pre-mRNA 5' splice site sequence.

SNRPC, PRPF39

GO:0030641

BP

regulation of cellular pH

Any process involved in the maintenance of an internal equilibrium of hydrogen ions (protons) within a cell or between a cell and its external environment.

MAFG

GO:0030643

BP

cellular phosphate ion homeostasis

Any process involved in the maintenance of an internal steady state of phosphate ions at the level of a cell.

ENPP1

GO:0030644

BP

cellular chloride ion homeostasis

Any process involved in the maintenance of an internal steady state of chloride ions at the level of a cell.

CKB

GO:0030656

BP

regulation of vitamin metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.

CD320

GO:0030658

CC

transport vesicle membrane

The lipid bilayer surrounding a transport vesicle.

HLA-DRA, HLA-DQA2, HLA-DQA1, HLA-DQB1, CD74, HLA-DRB4, CPE, HLA-DPA1, CA4, AQP2, CLCN3, VAMP7, HLA-DRB3, SNTB2, HLA-DRB5, ARFGEF3, SLC30A8, SYTL4, TMEM30A, RPH3AL

GO:0030659

CC

cytoplasmic vesicle membrane

The lipid bilayer surrounding a cytoplasmic vesicle.

TOR1A, PDE6D, KIF1B, TBC1D4, FZD6, ANXA1, RALA, SLC2A4, CLIP1, YWHAB, SFN, IFNGR2, HTT, RNF144A, AP3M2, AP1S2, AP3S2, AP1S1, YWHAE, RAB11A, YWHAZ, YWHAH, TNK2, SMAGP, AP1B1, MARCH8, STXBP5, ARHGAP21, DENND4C, AGTRAP, LRIG3, RAB11FIP2, C2CD5, ZDHHC17, GPRC5A, MARCH1, SNX33, SNX19, APPBP2, SNX21, ANKRD27, SNX18, GPER1, PACSIN1, GABARAPL1, RHBG, GPRC5C, SNX15, FMN2, GDE1, GPRC5B, FLRT1, LNPEP, LAMP5, RAB21, TAOK2, MYO5B, AP3M1, SNX24, SNX9, SNX5

GO:0030660

CC

Golgi-associated vesicle membrane

The lipid bilayer surrounding a vesicle associated with the Golgi apparatus.

GPR89A, CSPG5, GPR89B, CFTR, RHOQ, GJA1, PKD1, ZDHHC17, SPPL3, SPPL2A, HM13, GOPC, ITM2B

GO:0030663

CC

COPI-coated vesicle membrane

The lipid bilayer surrounding a COPI-coated vesicle.

KDELR1, TMED2

GO:0030665

CC

clathrin-coated vesicle membrane

The lipid bilayer surrounding a clathrin-coated vesicle.

HIP1, DAB2, VAMP3, DENND1A, CEMIP, MYO6

GO:0030666

CC

endocytic vesicle membrane

The lipid bilayer surrounding an endocytic vesicle.

WASL, AP2A2, HLA-DRA, HLA-DQA2, HLA-DQA1, HLA-DQB1, CD74, UBC, HLA-DRB4, CD36, HLA-DPA1, CD9, NOS3, WNT5A, GRIA4, AP2S1, WNT3, RPS27A, UBA52, AP2B1, DLG4, HLA-DRB3, MDM2, CAV1, CAMK2D, PTCH1, SCARF1, HLA-DRB5, COLEC12, WLS, CD163, NOSTRIN, SCARB1, STAB2, CACNG8, AP2M1, HBEGF, WNT5B, STAB1, WNT6

GO:0030667

CC

secretory granule membrane

The lipid bilayer surrounding a secretory granule.

EXOC3, CPE, PAM, CA4, TMED10, RAB27A, VAMP7, VAMP2, ICA1, ITPR2, ITPR3, SLC30A8, RPH3AL

GO:0030669

CC

clathrin-coated endocytic vesicle membrane

The lipid bilayer surrounding a clathrin-coated endocytic vesicle.

AP2A2, LDLR, HLA-DRA, HLA-DQA2, HLA-DQA1, HLA-DQB1, APOB, CD74, FCGR1A, HLA-DRB4, HLA-DPA1, CD9, WNT5A, AP2S1, AP1S2, AP1S1, AP2B1, HLA-DRB3, AP1B1, HLA-DRB5, FCGR1B, AP2M1, HBEGF, SH3GL2, FZD4

GO:0030670

CC

phagocytic vesicle membrane

The lipid bilayer surrounding a phagocytic vesicle.

ATP6V0E1, TLR2, ATG12, HLA-B, CYBB, ANXA3, LAMP2, HLA-E, RAC2, HLA-G, RAB5A, HLA-A, HLA-F, CORO1A, SLC11A1, RAB7A, RAB9A, VAMP7, ATP6V0D1, B2M, OCRL, TCIRG1, RAB31, RAB32, TLR1, RAB11B, RAB11FIP1, PIK3C3, RAB8B, ATP6V0A1, PIK3R4, RAB34, DMBT1, RAB22A, RAB23

GO:0030672

CC

synaptic vesicle membrane

The lipid bilayer surrounding a synaptic vesicle.

SCAMP1, SYNGR2, SYNGR3, SNAPIN, DRD2, SYN1, SYT1, VAMP2, ICA1, SLC18A2, RAB11B, SV2A, SV2B, DMXL2, SYN2, SYT11

GO:0030673

CC

axolemma

The portion of the plasma membrane surrounding an axon; it is a specialized trilaminar random mosaic of protein molecules floating within a fluid matrix of highly mobile phospholipid molecules, 7-8 nm in thickness.

MYO1D, ADORA1, CHRNA7, SLC1A2, SPTBN1, NRG1, KCNJ11, ROBO2, MAPK8IP3, EPB41L3

GO:0030674

MF

protein binding, bridging

The binding activity of a molecule that brings together two or more protein molecules, or a protein and another macromolecule or complex, through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way.

FLRT2, CSTA, FGA, FGB, FGG, ANXA1, COL1A2, NEFH, COL11A1, COL11A2, DSP, BCL3, COL8A2, CBX5, CAV2, TIRAP, ARPC4, PSMC6, CRADD, ANK2, FKBP4, CAV1, COL14A1, ANK3, CUX1, FSCN1, GATAD2A, WWC1, TRIM22, RAD50, OPTN, TRIM6, ADAP2, FLRT3, FLRT1, FRMD4A, TJP2, DDX20, NUFIP1, C14orf1, AMFR, STUB1

GO:0030676

MF

Rac guanyl-nucleotide exchange factor activity

Stimulates the exchange of guanyl nucleotides associated with a GTPase of the Rac family. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase.

FARP2, VAV1, TIAM1, PREX2, DOCK2, ARHGEF2, SPATA13, ALS2, ARHGEF4, VAV3, FARP1

GO:0030677

CC

ribonuclease P complex

A ribonucleoprotein complex that catalyzes cleavage of the leader sequence of precursor tRNAs (pre-tRNAs), generating the mature 5' end of tRNAs.

POP4

GO:0030686

CC

90S preribosome

A large ribonucleoprotein complex considered to be the earliest preribosomal complex. In S. cerevisiae, it has a size of 90S and consists of the 35S pre-rRNA, early-associating ribosomal proteins most of which are part of the small ribosomal subunit, the U3 snoRNA and associated proteins.

UTP20, RSL1D1, RPSA, RPS7

GO:0030687

CC

preribosome, large subunit precursor

A preribosomal complex consisting of 27SA, 27SB, and/or 7S pre-rRNA, 5S rRNA, ribosomal proteins including late-associating large subunit proteins, and associated proteins; a precursor of the eukaryotic cytoplasmic large ribosomal subunit.

NSA2, RPLP1, RPLP2, RPLP0, EIF6, BOP1, RRP1B, RRS1, WDR74, EBNA1BP2, WDR12, MDN1, MRTO4, NIP7, WDR37, LAS1L

GO:0030688

CC

preribosome, small subunit precursor

A preribosomal complex consisting of 20S pre-rRNA, ribosomal proteins including late-associating small subunit proteins, and associated proteins; a precursor of the eukaryotic cytoplasmic small ribosomal subunit.

UTP20, RRP1B, TSR1, NOB1

GO:0030690

CC

Noc1p-Noc2p complex

A heterodimer associated with 90S and 66S preribosomes. Predominantly, but not exclusively, nucleolar; involved in ribosomal large subunit biogenesis.

NOC2L

GO:0030691

CC

Noc2p-Noc3p complex

A heterodimer associated with 66S preribosomes; predominantly nucleoplasmic, but also locates to the nucleolus; involved in ribosomal large subunit biogenesis.

NOC2L

GO:0030695

MF

GTPase regulator activity

Modulates the rate of GTP hydrolysis by a GTPase.

WASL, KRIT1, RGS12, RALGDS, PCP2, RIN2, GOPC, GPSM3

GO:0030705

BP

cytoskeleton-dependent intracellular transport

The directed movement of substances along cytoskeletal fibers such as microfilaments or microtubules within a cell.

KIF1C, KIF5C, KIF1B, TUBB, TUBA1B, KIF14, TUBA1A, MYO10, KIF13B, STARD9

GO:0030728

BP

ovulation

The release of a mature ovum/oocyte from an ovary.

EREG, HPGD, IL4R, PTGS2, TNFAIP6, KMT2B

GO:0030729

MF

acetoacetate-CoA ligase activity

Catalysis of the reaction: acetoacetate + ATP + CoA = acetoacetyl-CoA + AMP + diphosphate + H(+).

AACS

GO:0030730

BP

sequestering of triglyceride

The process of binding or confining any triester of glycerol such that it is separated from other components of a biological system.

TNF, IL1B, ENPP1

GO:0030742

MF

GTP-dependent protein binding

Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules) using energy from the hydrolysis of GTP.

RAB3B, CDC42, RAB5B, RAC1, RAB32, EEA1, RAPGEF6, RAB34, PARD6A

GO:0030760

MF

pyridine N-methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine(1+) + pyridine = N-methylpyridinium + S-adenosyl-L-homocysteine.

NNMT

GO:0030791

MF

arsenite methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine + arsenite = S-adenosyl-L-homocysteine + methylarsonate.

AS3MT

GO:0030792

MF

methylarsonite methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine + methylarsonite = S-adenosyl-L-homocysteine + dimethylarsinate.

AS3MT

GO:0030801

BP

positive regulation of cyclic nucleotide metabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving cyclic nucleotides.

CALM2

GO:0030814

BP

regulation of cAMP metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).

DRD2, PDE4D, PKD2, NPHP3, TBL1XR1

GO:0030816

BP

positive regulation of cAMP metabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).

PF4

GO:0030818

BP

negative regulation of cAMP biosynthetic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).

GRM8, EDN1, EDNRA, OPRL1, NPY2R, AKAP6

GO:0030819

BP

positive regulation of cAMP biosynthetic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).

RAMP1, ABCA1, PTH, GCG, GHRH, ADRB1, SCT, PTHLH, NME2, MC4R, ADM, ADCYAP1R1, ADCY7, MC2R, MRAP, MRAP2, GPER1

GO:0030821

BP

negative regulation of cAMP catabolic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).

MAPK7

GO:0030822

BP

positive regulation of cAMP catabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).

RACK1

GO:0030823

BP

regulation of cGMP metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving cGMP.

PDE5A, THBS1, VEGFA

GO:0030825

BP

positive regulation of cGMP metabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving cGMP.

WNT5A

GO:0030828

BP

positive regulation of cGMP biosynthetic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cGMP.

APOE, MTNR1A

GO:0030832

BP

regulation of actin filament length

Any process that controls the length of actin filaments in a cell.

EPS8

GO:0030833

BP

regulation of actin filament polymerization

Any process that modulates the frequency, rate or extent of the assembly of actin filaments by the addition of actin monomers to a filament.

HAX1, PAK3, FCHSD2, LATS1, HCLS1, RASA1, ARHGAP18

GO:0030834

BP

regulation of actin filament depolymerization

Any process that modulates the frequency, rate or extent of the disassembly of actin filaments by the removal of actin monomers from a filament.

WDR1, SH3BGRL3

GO:0030835

BP

negative regulation of actin filament depolymerization

Any process that stops, prevents, or reduces the frequency, rate or extent of actin depolymerization.

PLEKHH2, LIMA1

GO:0030836

BP

positive regulation of actin filament depolymerization

Any process that activates or increases the frequency, rate or extent of actin depolymerization.

WDR1, F2RL1, DSTN, SEMA5A

GO:0030837

BP

negative regulation of actin filament polymerization

Any process that stops, prevents, or reduces the frequency, rate or extent of actin polymerization.

SLIT2, PFN1, PRKCD, TWF1, KANK1, TWF2, MYADM, MKKS

GO:0030838

BP

positive regulation of actin filament polymerization

Any process that activates or increases the frequency, rate or extent of actin polymerization.

MYO1C, ICAM1, PFN1, ALOX15, LMOD1, GRB2, RAC1, DLG1, CTTN, LRRC16A, RICTOR, MLST8, BAIAP2L1, EVL, CDC42EP3, PYCARD

GO:0030844

BP

positive regulation of intermediate filament depolymerization

Any process that activates or increases the frequency, rate or extent of intermediate filament depolymerization.

NES

GO:0030849

CC

autosome

Any chromosome other than a sex chromosome.

SIN3B

GO:0030850

BP

prostate gland development

The process whose specific outcome is the progression of the prostate gland over time, from its formation to the mature structure. The prostate gland is a partly muscular, partly glandular body that is situated near the base of the mammalian male urethra and secretes an alkaline viscid fluid which is a major constituent of the ejaculatory fluid.

ANXA1, AR, SOX9, FKBP4, SMARCC1

GO:0030851

BP

granulocyte differentiation

The process in which a myeloid precursor cell acquires the specialized features of a granulocyte. Granulocytes are a class of leukocytes characterized by the presence of granules in their cytoplasm. These cells are active in allergic immune reactions such as arthritic inflammation and rashes. This class includes basophils, eosinophils and neutrophils.

KDM1A, SP3, NKAP, L3MBTL3

GO:0030853

BP

negative regulation of granulocyte differentiation

Any process that stops, prevents, or reduces the frequency, rate or extent of granulocyte differentiation.

CUL4A, ADIPOQ

GO:0030854

BP

positive regulation of granulocyte differentiation

Any process that activates or increases the frequency, rate or extent of granulocyte differentiation.

HAX1, OGT, HCLS1, RUNX1, KMT2E

GO:0030855

BP

epithelial cell differentiation

The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell, any of the cells making up an epithelium.

NR5A2, TPP1, TBX1, CBFA2T2, TCF21, PGK1, CDK1, CTSB, GSTA1, ANXA4, ALDOC, PCNA, KRT3, VEGFA, CBR1, LGALS3, WT1, FGFR2, HNRNPH3, PPARG, TAGLN2, ACADVL, CPT1A, AKR1C2, CASP6, DLX5, ELF3, TAGLN, ID3, AKR1C1, CNN3, PTER, DHRS9, BDH2, CDHR2, TOLLIP, EHF, DMBT1, GSTK1

GO:0030856

BP

regulation of epithelial cell differentiation

Any process that modulates the frequency, rate or extent of epithelial cell differentiation.

PRLR, CD24, ASCL1, STAT5B

GO:0030857

BP

negative regulation of epithelial cell differentiation

Any process that stops, prevents, or reduces the frequency, rate or extent of epithelial cell differentiation.

ZEB1, YAP1, SOX9, CAV1, OSR1

GO:0030858

BP

positive regulation of epithelial cell differentiation

Any process that activates or increases the frequency, rate or extent of epithelial cell differentiation.

SOX9

GO:0030859

BP

polarized epithelial cell differentiation

The process in which a relatively unspecialized cell acquires specialized features of a polarized epithelial cell. The polarized epithelial cell can be any of the cells within an epithelium where the epithelial sheet is oriented with respect to the planar axis.

DLG5

GO:0030862

BP

positive regulation of polarized epithelial cell differentiation

Any process that activates or increases the rate or extent of polarized epithelial cell differentiation.

NUMB, AHI1