Search Geneontologies

Geneontologies

GO ID Ontology GO Term Term Definition Proteins

GO:0019265

BP

glycine biosynthetic process, by transamination of glyoxylate

The chemical reactions and pathways resulting in the formation of glycine by the transamination of glyoxylate.

AGXT

GO:0019276

BP

UDP-N-acetylgalactosamine metabolic process

The chemical reactions and pathways involving UDP-N-acetylgalactosamine, a substance composed of N-acetylgalactosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate.

CSGALNACT1

GO:0019285

BP

glycine betaine biosynthetic process from choline

The chemical reactions and pathways resulting in the formation of betaine (N-trimethylglycine) from the oxidation of choline.

ALDH7A1

GO:0019287

BP

isopentenyl diphosphate biosynthetic process, mevalonate pathway

The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate, via the intermediate mevalonate. This pathway converts acetate, in the form of acetyl-CoA, to isopentenyl diphosphate (IPP), the fundamental unit in isoprenoid biosynthesis, through a series of mevalonate intermediates.

MVD, MVK

GO:0019290

BP

siderophore biosynthetic process

The chemical reactions and pathways resulting in the formation of siderophores, low molecular weight Fe(III)-chelating substances made by aerobic or facultatively anaerobic bacteria, especially when growing under iron deficient conditions. The complexes of Fe(3+)-siderophores have very high stability constants and are taken up by specific transport systems by microorganisms; the subsequent release of iron requires enzymatic action.

BDH2

GO:0019303

BP

D-ribose catabolic process

The chemical reactions and pathways resulting in the breakdown of D-ribose (ribo-pentose).

NUDT5

GO:0019310

BP

inositol catabolic process

The chemical reactions and pathways resulting in the breakdown of inositol, 1,2,3,4,5,6-cyclohexanehexol, a growth factor for animals and microorganisms.

MIOX

GO:0019318

BP

hexose metabolic process

The chemical reactions and pathways involving a hexose, any monosaccharide with a chain of six carbon atoms in the molecule.

HKDC1

GO:0019319

BP

hexose biosynthetic process

The chemical reactions and pathways resulting in the formation of hexose, any monosaccharide with a chain of six carbon atoms in the molecule.

CHST15

GO:0019322

BP

pentose biosynthetic process

The chemical reactions and pathways resulting in the formation of a pentose, any monosaccharide with a chain of five carbon atoms in the molecule.

G6PD, PGD

GO:0019341

BP

dibenzo-p-dioxin catabolic process

The chemical reactions and pathways resulting in the breakdown of dibenzo-p-dioxin, a substance composed of two benzene rings linked by two ether bonds.

CYP1A1

GO:0019343

BP

cysteine biosynthetic process via cystathionine

The chemical reactions and pathways resulting in the formation of cysteine, via the intermediate cystathionine.

CTH, CBS

GO:0019344

BP

cysteine biosynthetic process

The chemical reactions and pathways resulting in the formation of cysteine, 2-amino-3-mercaptopropanoic acid.

CTH, CBS

GO:0019346

BP

transsulfuration

The interconversion of homocysteine and cysteine via cystathionine. In contrast with enteric bacteria and mammals, Saccharomyces cerevisiae has two transsulfuration pathways employing two separate sets of enzymes.

MTHFD1, MPST, CTH, CBS

GO:0019367

BP

fatty acid elongation, saturated fatty acid

Elongation of a saturated fatty acid chain.

ELOVL7, ELOVL1, ELOVL4, ELOVL6, ELOVL5

GO:0019369

BP

arachidonic acid metabolic process

The chemical reactions and pathways involving arachidonic acid, a straight chain fatty acid with 20 carbon atoms and four double bonds per molecule. Arachidonic acid is the all-Z-(5,8,11,14)-isomer.

CYP2D6, ALOX15, MAPK3, PLA2G4A, CYP1B1, DAGLB, MGLL, PNPLA8, PLA2G4C

GO:0019370

BP

leukotriene biosynthetic process

The chemical reactions and pathways resulting in the formation of leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid.

ALOX5, PLA2G5, SYK, MGST2, GGT7

GO:0019371

BP

cyclooxygenase pathway

The chemical reactions and pathways by which prostaglandins are formed from arachidonic acid, and in which prostaglandin-endoperoxide synthase (cyclooxygenase) catalyzes the committed step in the conversion of arachidonic acid to the prostaglandin-endoperoxides PGG2 and PGH2.

PTGES, CBR1, PTGS1, PTGS2, PTGDS, AKR1C3, PTGES3, PTGIS

GO:0019372

BP

lipoxygenase pathway

The chemical reactions and pathways by which an unsaturated fatty acid (such as arachidonic acid or linolenic acid) is converted to other compounds, and in which the first step is hydroperoxide formation catalyzed by lipoxygenase.

GPX1, ALOX5, HPGD, ALOX15, PTGS2, GPX4

GO:0019373

BP

epoxygenase P450 pathway

The chemical reactions and pathways by which arachidonic acid is converted to other compounds including epoxyeicosatrienoic acids and dihydroxyeicosatrienoic acids.

CYP1A1, CYP2E1, CYP2A6, CYP2C9, CYP2B6, CYP1B1

GO:0019388

BP

galactose catabolic process

The chemical reactions and pathways resulting in the breakdown of galactose, the aldohexose galacto-hexose.

GALT, PGM1, GALE, PGM2

GO:0019391

BP

glucuronoside catabolic process

The chemical reactions and pathways resulting in the breakdown of glucuronosides, compound composed of a hydroxy compound linked to a glucuronate residue.

ABHD10

GO:0019395

BP

fatty acid oxidation

The removal of one or more electrons from a fatty acid, with or without the concomitant removal of a proton or protons, by reaction with an electron-accepting substance, by addition of oxygen or by removal of hydrogen.

PPARG, ACOX1, ADIPOQ, MAPK14, ADIPOR2, CYGB, ADIPOR1, HAO2, PPARGC1A

GO:0019413

BP

acetate biosynthetic process

The chemical reactions and pathways resulting in the formation of acetate, the anion of acetic acid.

ACSS2, ACSS1

GO:0019417

BP

sulfur oxidation

The chemical reactions and pathways resulting the addition of oxygen to elemental sulfur.

MICAL2, MICAL1

GO:0019427

BP

acetyl-CoA biosynthetic process from acetate

The chemical reactions and pathways resulting in the formation of acetyl-CoA from acetate, either directly or via acetylphosphate.

ACSS2, ACSS1

GO:0019430

BP

removal of superoxide radicals

Any process, acting at the cellular level, involved in removing superoxide radicals (O2-) from a cell or organism, e.g. by conversion to dioxygen (O2) and hydrogen peroxide (H2O2).

CCS, SOD2, MPO, SOD3, NQO1, MT3, NOS3, PRDX2, PRDX1

GO:0019432

BP

triglyceride biosynthetic process

The chemical reactions and pathways resulting in the formation of a triglyceride, any triester of glycerol.

LPL, GK, LPIN1, GPAT3, LCLAT1, GPAT4, DGAT2, GPAM, AGPAT4, AGPAT3, PNPLA3

GO:0019433

BP

triglyceride catabolic process

The chemical reactions and pathways resulting in the breakdown of a triglyceride, any triester of glycerol.

FABP12, APOA1, APOE, APOC3, APOB, FABP3, LPL, FABP4, FABP6, FABP5, LIPE, APOA5, PNPLA5, PNPLA2, MGLL, PNPLA3

GO:0019439

BP

aromatic compound catabolic process

The chemical reactions and pathways resulting in the breakdown of aromatic compounds, any substance containing an aromatic carbon ring.

EPHX1, PON1

GO:0019441

BP

tryptophan catabolic process to kynurenine

The chemical reactions and pathways resulting in the breakdown of tryptophan into other compounds, including kynurenine.

KMO, KYNU

GO:0019442

BP

tryptophan catabolic process to acetyl-CoA

The chemical reactions and pathways resulting in the breakdown of tryptophan into other compounds, including acetyl-CoA.

KYNU

GO:0019448

BP

L-cysteine catabolic process

The chemical reactions and pathways resulting in the breakdown of L-cysteine, the L-enantiomer of 2-amino-3-mercaptopropanoic acid, i.e. (2R)-2-amino-3-mercaptopropanoic acid.

AGXT, CBS, CDO1

GO:0019451

BP

L-cysteine catabolic process to pyruvate, using cysteine dioxygenase

The chemical reactions and pathways resulting in the breakdown into pyruvate of L-cystine, catalyzed by the enzyme cysteine dioxygenase (EC:1.13.11.20).

CDO1

GO:0019464

BP

glycine decarboxylation via glycine cleavage system

The chemical reactions and pathways resulting in the breakdown of glycine by oxidative cleavage to carbon dioxide, ammonia, and a methylene group, mediated by enzymes of the glycine cleavage complex.

GCSH

GO:0019470

BP

4-hydroxyproline catabolic process

The chemical reactions and pathways resulting in the breakdown of 4-hydroxyproline, C5H9NO3, a derivative of the amino acid proline.

PRODH, GOT2

GO:0019471

BP

4-hydroxyproline metabolic process

The chemical reactions and pathways involving 4-hydroxyproline, C5H9NO3, a derivative of the amino acid proline. The presence of hydroxyproline is essential to produce stable triple helical tropocollagen, hence the problems caused by ascorbate deficiency in scurvy. This unusual amino acid is also present in considerable amounts in the major glycoprotein of primary plant cell walls.

PRDX4, ERO1B, ERO1A

GO:0019478

BP

D-amino acid catabolic process

The chemical reactions and pathways resulting in the breakdown of D-amino acids, the D-enantiomers of amino acids.

DTD2

GO:0019482

BP

beta-alanine metabolic process

The chemical reactions and pathways involving beta-alanine (3-aminopropanoic acid), an achiral amino acid and an isomer of alanine. It occurs free (e.g. in brain) and in combination (e.g. in pantothenate) but it is not a constituent of proteins.

AASDH

GO:0019483

BP

beta-alanine biosynthetic process

The chemical reactions and pathways resulting in the formation of beta-alanine (3-aminopropanoic acid), an achiral amino acid and an isomer of alanine. It occurs free (e.g. in brain) and in combination (e.g. in pantothenate) but it is not a constituent of proteins.

DPYD

GO:0019509

BP

L-methionine biosynthetic process from methylthioadenosine

The generation of L-methionine (2-amino-4-(methylthio)butanoic acid) from methylthioadenosine.

MTAP, ADI1

GO:0019510

BP

S-adenosylhomocysteine catabolic process

The chemical reactions and pathways resulting in the breakdown of S-adenosylhomocysteine, forming homocysteine and then methionine.

AHCY

GO:0019511

BP

peptidyl-proline hydroxylation

The hydroxylation of peptidyl-proline to form peptidyl-hydroxyproline.

P4HA2, P3H2

GO:0019521

BP

D-gluconate metabolic process

The chemical reactions and pathways involving D-gluconate, the anion of D-gluconic acid, the aldonic acid derived from glucose.

PGD

GO:0019530

BP

taurine metabolic process

The chemical reactions and pathways involving taurine (2-aminoethanesulfonic acid), a sulphur-containing amino acid derivative important in the metabolism of fats.

PHGDH, GHR, STAT5A, STAT5B

GO:0019531

MF

oxalate transmembrane transporter activity

Enables the transfer of oxalate from one side of the membrane to the other. Oxalate, or ethanedioic acid, occurs in many plants and is highly toxic to animals.

SLC26A2, SLC26A11, SLC26A1

GO:0019532

BP

oxalate transport

The directed movement of oxalate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Oxalate, or ethanedioic acid, occurs in many plants and is highly toxic to animals.

SLC26A2, SLC26A11, SLC26A1

GO:0019534

MF

toxin transporter activity

Enables the directed movement of a toxin into, out of or within a cell, or between cells. A toxin is a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism.

LRP6, SLC22A3, SLC7A8

GO:0019538

BP

protein metabolic process

The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification.

BAG2, MMP16, NECAB3

GO:0019542

BP

propionate biosynthetic process

The chemical reactions and pathways resulting in the formation of propionate, the anion derived from propionic acid.

ACSS2, ACSS1

GO:0019550

BP

glutamate catabolic process to aspartate

The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including aspartate.

GOT2

GO:0019551

BP

glutamate catabolic process to 2-oxoglutarate

The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including 2-oxoglutarate.

GOT2

GO:0019563

BP

glycerol catabolic process

The chemical reactions and pathways resulting in the breakdown of glycerol, 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids.

GK, GPD2, TPI1, GK5

GO:0019626

BP

short-chain fatty acid catabolic process

The chemical reactions and pathways resulting in the breakdown of fatty acids with a chain length of less than C6.

PCCA, MMAA, MCEE

GO:0019627

BP

urea metabolic process

The chemical reactions and pathways involving urea, the water soluble compound O=C-(NH2)2.

CYP2C9

GO:0019640

BP

glucuronate catabolic process to xylulose 5-phosphate

The chemical reactions and pathways resulting in the breakdown of glucuronate into other compounds, including xylulose 5-phosphate.

SORD, DCXR, CRYL1

GO:0019673

BP

GDP-mannose metabolic process

The chemical reactions and pathways involving GDP-mannose, a substance composed of mannose in glycosidic linkage with guanosine diphosphate.

GMDS, GUK1

GO:0019674

BP

NAD metabolic process

The chemical reactions and pathways involving nicotinamide adenine dinucleotide (NAD), a coenzyme present in most living cells and derived from the B vitamin nicotinic acid.

KMO, LDHA, LDHB, QPRT, NADK2, NADSYN1, NMNAT3

GO:0019695

BP

choline metabolic process

The chemical reactions and pathways involving choline (2-hydroxyethyltrimethylammonium), an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine.

CHKA, DMGDH

GO:0019706

MF

protein-cysteine S-palmitoyltransferase activity

Catalysis of the transfer of a palmitoyl group to a sulfur atom on the cysteine of a protein molecule.

ZDHHC20, ZDHHC17, ZDHHC14, ZDHHC6, ZDHHC7, ZDHHC2, ZDHHC9

GO:0019722

BP

calcium-mediated signaling

Any intracellular signal transduction in which the signal is passed on within the cell via calcium ions.

TNFSF11, EDN1, CXCL8, CCL3, SELE, PLCG2, EDN2, AGTR1, HTR2B, CXCR4, NCALD, MCTP1, TPCN2, RYR2, SPHK1

GO:0019724

BP

B cell mediated immunity

Any process involved with the carrying out of an immune response by a B cell, through, for instance, the production of antibodies or cytokines, or antigen presentation to T cells.

FAS, MSH2

GO:0019725

BP

cellular homeostasis

Any process involved in the maintenance of an internal steady state at the level of the cell.

CCL2, MCL1, TNS2

GO:0019730

BP

antimicrobial humoral response

An immune response against microbes mediated through a body fluid. Examples of this process are seen in the antimicrobial humoral response of Drosophila melanogaster and Mus musculus.

DEFA4, BCL3

GO:0019731

BP

antibacterial humoral response

An immune response against bacteria mediated through a body fluid. Examples of this process are the antibacterial humoral responses in Mus musculus and Drosophila melanogaster.

HIST1H2BK, ANG, SLPI, APP, DEFA4, HLA-E, ADM, B2M, HIST1H2BC, HIST2H2BE

GO:0019732

BP

antifungal humoral response

An immune response against a fungus mediated through a body fluid. An example of this process is the antifungal humoral response in Drosophila melanogaster.

ANG, APP

GO:0019740

BP

nitrogen utilization

A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary nitrogen source, usually ammonia, and then activates genes to scavenge the last traces of the primary nitrogen source and to transport and metabolize alternative nitrogen sources. The utilization process begins when the cell or organism detects nitrogen levels, includes the activation of genes whose products detect, transport or metabolize nitrogen-containing substances, and ends when nitrogen is incorporated into the cell or organism's metabolism.

RHBG

GO:0019747

BP

regulation of isoprenoid metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving isoprenoids.

NPC2

GO:0019752

BP

carboxylic acid metabolic process

The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-).

MIF, CSAD

GO:0019763

MF

immunoglobulin receptor activity

Combining with the Fc region of an immunoglobulin protein and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.

FCGR1B

GO:0019773

CC

proteasome core complex, alpha-subunit complex

The proteasome core subcomplex that constitutes the two outer rings of the proteasome core complex. An example of this component is found in Mus musculus.

PSMA1, PSMA2, PSMA3, PSMA4

GO:0019774

CC

proteasome core complex, beta-subunit complex

The proteasome core subcomplex that constitutes the two inner rings of the proteasome core complex. An example of this component is found in Mus musculus.

PSMB3

GO:0019776

MF

Atg8 ligase activity

Catalysis of the covalent attachment of the ubiquitin-like protein Atg8 to substrate molecules; phosphatidylethanolamine is a known substrate.

ATG12

GO:0019777

MF

Atg12 transferase activity

Catalysis of the transfer of ATG12 from one protein to another via the reaction X-ATG12 + Y --> Y-ATG12 + X, where both X-ATG12 and Y-ATG12 are covalent linkages.

ATG10

GO:0019780

MF

FAT10 activating enzyme activity

Catalysis of the activation of the small ubiquitin-related modifier FAT10, through the formation of an ATP-dependent high-energy thiolester bond.

UBA6

GO:0019781

MF

NEDD8 activating enzyme activity

Catalysis of the initiation of the NEDD8 (RUB1) conjugation cascade.

NAE1

GO:0019782

MF

ISG15 activating enzyme activity

Catalysis of the activation of the small ubiquitin-related modifier ISG15, through the formation of an ATP-dependent high-energy thiolester bond.

UBA7

GO:0019784

MF

NEDD8-specific protease activity

Catalysis of the hydrolysis of NEDD8, a small ubiquitin-related modifier, from previously neddylated substrates.

OTUB2, OTUB1

GO:0019787

MF

ubiquitin-like protein transferase activity

Catalysis of the transfer of a ubiquitin-like from one protein to another via the reaction X-ULP + Y --> Y-ULP + X, where both X-ULP and Y-ULP are covalent linkages. ULP represents a ubiquitin-like protein.

ITCH, RNF14, ARIH1

GO:0019788

MF

NEDD8 transferase activity

Catalysis of the transfer of NEDD8 from one protein to another via the reaction X-NEDD8 + Y --> Y-NEDD8 + X, where both X-NEDD8 and Y-NEDD8 are covalent linkages.

UBE2M, RBX1

GO:0019789

MF

SUMO transferase activity

Catalysis of the transfer of SUMO from one protein to another via the reaction X-SUMO + Y --> Y-SUMO + X, where both X-SUMO and Y-SUMO are covalent linkages.

RANBP2, SUMO2, UBE2I, MDM2, HDAC7

GO:0019797

MF

procollagen-proline 3-dioxygenase activity

Catalysis of the reaction: procollagen L-proline + 2-oxoglutarate + O2 = procollagen trans-3-hydroxy-L-proline + succinate + CO2.

P3H2

GO:0019800

BP

peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan

The formation of a cross-link between peptide chains mediated by a chondroitin 4-sulfate glycosaminoglycan that originates from a typical O-glycosidic link to serine of one chain; the other chain is esterified, via the alpha-carbon of its C-terminal Asp, to C-6 of an internal N-acetylgalactosamine of the glycosaminoglycan chain.

DCN, BGN, NDNF, SPOCK2, SPOCK3

GO:0019805

BP

quinolinate biosynthetic process

The chemical reactions and pathways resulting in the formation of quinolinate, the anion of quinolinic acid, also known as 2,3-pyridinedicarboxylic acid.

KMO, KYNU

GO:0019809

MF

spermidine binding

Interacting selectively and non-covalently with spermidine, N-(3-aminopropyl)-1,4-diaminobutane.

SAT1, SAT2

GO:0019810

MF

putrescine binding

Interacting selectively and non-covalently with putrescine, 1,4-diaminobutane, the polyamine formed by decarboxylation of ornithine and the metabolic precursor of spermidine and spermine.

AMD1

GO:0019815

CC

B cell receptor complex

An immunoglobulin complex that is present in the plasma membrane of B cells and that in its canonical form is composed of two identical immunoglobulin heavy chains and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins.

SYK

GO:0019825

MF

oxygen binding

Interacting selectively and non-covalently with oxygen (O2).

CYP26A1, ALB, CYP1A1, CYP17A1, CYP2E1, TH, CYP3A4, CYP2D6, CYP19A1, CYP2C9, CYP2B6, CYP3A5, CYP3A7, CBS, HBB, HBG1, HBA1, CYP1B1, CYP2U1, CYGB, NGB, CYP8B1

GO:0019826

MF

oxygen sensor activity

Interacting selectively and non-covalently with and responding, e.g. by conformational change, to changes in the cellular level of oxygen (O2).

NOX4

GO:0019827

BP

stem cell population maintenance

The process by which an organism or tissue maintains a population of stem cells of a single type. This can be achieved by a number of mechanisms: stem cell asymmetric division maintains stem cell numbers; stem cell symmetric division increases them; maintenance of a stem cell niche maintains the conditions for commitment to the stem cell fate for some types of stem cell; stem cells may arise de novo from other cell types.

KLF4, MED7, MED14, FZD7, EIF4E, KIT, LIF, CTNNB1, BMPR1A, NOTCH2, MED21, SMC1A, RIF1, NIPBL, NKAP, SETD6, RTF1, MED12, MED30, TRIM8, LIN28A, METTL14, EIF4ENIF1, MED17, ZNF358, PADI4, SMC3, MTF2

GO:0019828

MF

aspartic-type endopeptidase inhibitor activity

Stops, prevents or reduces the activity of aspartic-type endopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide bonds in a polypeptide chain; the optimum reaction pH is below 5 due to an aspartic residue involved in the catalytic process.

WFDC2

GO:0019829

MF

cation-transporting ATPase activity

Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + cation(out) = ADP + phosphate + cation(in).

ATP13A5, ATP13A3, ATP13A2

GO:0019834

MF

phospholipase A2 inhibitor activity

Stops, prevents or reduces the activity of the enzyme phospholipase A2.

ANXA1, ANXA2, ANXA3

GO:0019835

BP

cytolysis

The rupture of cell membranes and the loss of cytoplasm.

C8G, C7, C6, LYZ, MMD, MICB, MICA

GO:0019836

BP

hemolysis by symbiont of host erythrocytes

The cytolytic destruction of red blood cells, with the release of intracellular hemoglobin, in the host organism by a symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.

ALB

GO:0019838

MF

growth factor binding

Interacting selectively and non-covalently with any growth factor, proteins or polypeptides that stimulate a cell or organism to grow or proliferate.

SDCBP, NRP1, NRP2, A2M, ERBB2, ERBB3, ACVR2A, DUSP1, FLT4, ACVR1B, TGFBR1, IL6ST, LIFR, TEK, ACVR2B, BMPR2, RHBDF1, OSMR

GO:0019840

MF

isoprenoid binding

Interacting selectively and non-covalently with any isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues.

PGGT1B

GO:0019841

MF

retinol binding

Interacting selectively and non-covalently with retinol, vitamin A1, 2,6,6-trimethyl-1-(9'-hydroxy-3',7'-dimethylnona-1',3',5',7'-tetraenyl)cyclohex-1-ene, one of the three components that makes up vitamin A. Retinol is an intermediate in the vision cycle and it also plays a role in growth and differentiation.

RBP4, C8G, RBP1, ADH7

GO:0019843

MF

rRNA binding

Interacting selectively and non-covalently with ribosomal RNA.

ANG, RPS4Y1, RPL12, RPS9, RPS5, RPL37, RPS18, RPS11, RPL23A, RPL11, RNASEL, EMG1, PTCD3, DDX28, MRPL16, NOL12, SBDS

GO:0019852

BP

L-ascorbic acid metabolic process

The chemical reactions and pathways involving L-ascorbic acid, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate; L-ascorbic acid is vitamin C and has co-factor and anti-oxidant activities in many species.

CYB5A, CYB5R3, SLC2A1, SLC2A3, GCLC, GSTO1, GSTO2, SLC23A2

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