| GO ID | Ontology | GO Term | Term Definition |
Proteins |
GO:0010454 | BP | negative regulation of cell fate commitment | Any process that stops, prevents or reduces the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field. |
SOSTDC1 |
GO:0010457 | BP | centriole-centriole cohesion | The process in which the two centrioles within a centrosome remain tightly paired. |
SGOL1, CROCC, CEP135 |
GO:0010458 | BP | exit from mitosis | The cell cycle transition where a cell leaves M phase and enters a new G1 phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place. |
UBE2C, CHMP2A, RPL24, EPS8, UBE2S, CHMP4B, SPAST |
GO:0010459 | BP | negative regulation of heart rate | Any process that stops, prevents or reduces the frequency or rate of heart contraction. |
PLN, SRI, AGTR2, SPX, SPTBN4 |
GO:0010460 | BP | positive regulation of heart rate | Any process that activates or increases the frequency or rate of heart contraction. |
ADA, EDN1, ATP2A2, EDN2, ADM, TRPM4, RYR2 |
GO:0010463 | BP | mesenchymal cell proliferation | The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets. |
FGF7 |
GO:0010464 | BP | regulation of mesenchymal cell proliferation | Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets. |
ZEB1 |
GO:0010465 | MF | nerve growth factor receptor activity | Combining with nerve growth factor (NGF), to prevent apoptosis in neurons and promote nerve growth, or to initiate a change in cell activity. |
NTRK1 |
GO:0010466 | BP | negative regulation of peptidase activity | Any process that stops or reduces the rate of peptidase activity, the hydrolysis of peptide bonds within proteins. |
SSPO, PI15, CST3, CSTA, CSTB, SERPINB3, SERPINB4, PI16 |
GO:0010467 | BP | gene expression | The process in which a gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form. |
IGF2BP3, POLR2D, HNRNPR, HNRNPC, HNRNPA1, GTF2F2, HNRNPL, POLR2E, HNRNPA2B1, POLR2A, FAS, PTBP1, POLR2B, HNRNPH1, GTF2F1, POLR2I, RBMX, HNRNPA3, HNRNPM, POLR2J, POLR2K, HNRNPH2, POLR2G, POLR2L, HNRNPU, NCBP1, HNRNPD, WTAP, PCBP1, METTL14, NOX4, IGF2BP2 |
GO:0010468 | BP | regulation of gene expression | Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form. |
DDX39A, UTY, PHGDH, F2, MYC, GNRH1, PTH, APOE, IGF1, ATP1B1, BCL2, CDK4, PTHLH, PLCG2, IL10, G6PC, AHR, TGFBR2, PIK3CA, ASCL1, EIF4A1, PPP2CB, CDK6, INSM1, POU5F1, APBA1, ZFP36L1, ALKBH1, TOB2, NPAT, SART3, ASIC2, HIF1A, PHLDA2, STXBP5, RICTOR, MSANTD1, DDX46, STAB2, PROX1, FAM46A, FUT8, MAPK8IP3, KIAA0430, MAP3K4 |
GO:0010469 | BP | regulation of receptor activity | Any process that modulates the frequency, rate or extent of receptor activity. Receptor activity is when a molecule combines with an extracellular or intracellular messenger to initiate a change in cell activity. |
PLAU, SERPINE1, PRKCD, PDE4D, MAPK8IP2, PPP2R5B, PCSK9, HDAC6 |
GO:0010470 | BP | regulation of gastrulation | Any process that modulates the rate or extent of gastrulation. Gastrulation is the complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals. |
DAG1, PHLDB2, PHLDB1 |
GO:0010477 | BP | response to sulfur dioxide | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sulfur dioxide (SO2) stimulus. |
ICAM1 |
GO:0010482 | BP | regulation of epidermal cell division | Any process that modulates the frequency, rate or extent of the physical partitioning and separation of an epidermal cell into daughter cells. An epidermal cell is any of the cells that make up the epidermis. |
SFN |
GO:0010484 | MF | H3 histone acetyltransferase activity | Catalysis of the reaction: acetyl-CoA + histone H3 = CoA + acetyl-histone H3. |
BRCA2, ELP3 |
GO:0010485 | MF | H4 histone acetyltransferase activity | Catalysis of the reaction: acetyl-CoA + histone H4 = CoA + acetyl-histone H4. |
BRCA2, NAA50, NAA60, ELP3, USP22 |
GO:0010494 | CC | cytoplasmic stress granule | A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress. |
FAM195B, DDX3X, PQBP1, STAU1, EIF2S1, EIF4E, ZFP36, TIA1, YBX1, G3BP1, CIRBP, CAPRIN1, PUM1, NUFIP2, LSM14A, PUM2, ATXN2L, KHSRP, RBPMS, FAM195A, RBM4, LIN28A, MBNL1 |
GO:0010498 | BP | proteasomal protein catabolic process | The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome. |
SOCS6, PARK2, NR1D1, AGXT, PMAIP1, PRPF19 |
GO:0010499 | BP | proteasomal ubiquitin-independent protein catabolic process | The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome but do not involve ubiquitin. |
ENC1, PSME4 |
GO:0010501 | BP | RNA secondary structure unwinding | The process in which a secondary structure of RNA are broken or 'melted'. |
DDX39A, DDX3X, DDX5, EIF4A1, EIF4A2, DDX46, DDX54, DDX17, DDX27, DDX23, DDX24, DDX47, DHX36, DDX31, AGO4, DDX28, DDX43, DDX20, AGO2, DDX52, DDX49 |
GO:0010506 | BP | regulation of autophagy | Any process that modulates the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm. |
DAPK3, PARK2, ULK1, HSPB1, PSAP, HMGB1, MAPT, XBP1, CASP1, ABL2, DAPK1, PIP4K2B, EP300, ITPR1, IFI16, DRAM2, CISD2, DRAM1, TPCN2, USP13, NRBF2, VMP1, RRAGC, RRAGD, HDAC6, FBXL2, PYCARD, BOK, LAMP3 |
GO:0010507 | BP | negative regulation of autophagy | Any process that stops, prevents, or reduces the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm. |
DAPL1, WASH1, MET, BCL2, HGF, MT3, AKT1, LEP, HTR2B, GATA4, LEPR, DAP, MCL1, GOLGA2, SIRT2, TAB3, TBC1D14, PTPN22 |
GO:0010508 | BP | positive regulation of autophagy | Any process that activates, maintains or increases the rate of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm. |
ULK1, DCN, TFEB, PIK3CB, PRKAA2, FOXO1, BNIP3, STK11, MTDH, TP53INP2, TRIM22, RNF152, FLCN, SVIP, TBC1D5, BAD, TP53INP1, TMEM59, TRIM8, PLK2, SH3BP4, SH3GLB1 |
GO:0010509 | BP | polyamine homeostasis | Any biological process involved in the maintenance of an internal steady state of a polyamine. |
EIF5A2 |
GO:0010510 | BP | regulation of acetyl-CoA biosynthetic process from pyruvate | Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of acetyl-CoA from pyruvate. |
PDHA1, DLD, DLAT, PDHB, PDK1, PDK4, PDP1 |
GO:0010512 | BP | negative regulation of phosphatidylinositol biosynthetic process | Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phosphatidylinositol. |
PDGFB, PDGFA |
GO:0010513 | BP | positive regulation of phosphatidylinositol biosynthetic process | Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phosphatidylinositol. |
ZP3, HTR2C, HTR2B |
GO:0010517 | BP | regulation of phospholipase activity | Any process that modulates the frequency, rate or extent of phospholipase activity, the hydrolysis of a phospholipid. |
SNCA |
GO:0010518 | BP | positive regulation of phospholipase activity | Any process that increases the frequency, rate or extent of phospholipase activity, the hydrolysis of a phospholipid. |
CYR61, FGFR1, FGFR2, PLA2G5 |
GO:0010519 | BP | negative regulation of phospholipase activity | Any process that decreases the frequency, rate or extent of phospholipase activity, the hydrolysis of a phospholipid. |
RGS2 |
GO:0010521 | MF | telomerase inhibitor activity | Stops, prevents or reduces the activity of a telomerase. Telomerase catalyzes the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Catalyzes extension of the 3'- end of a DNA strand by one deoxynucleotide at a time using an internal RNA template that encodes the telomeric repeat sequence. |
PIF1, OBFC1, POT1 |
GO:0010523 | BP | negative regulation of calcium ion transport into cytosol | Any process that decreases the rate of the directed movement of calcium ions into the cytosol of a cell. The cytosol is that part of the cytoplasm that does not contain membranous or particulate subcellular components. |
BCL2 |
GO:0010524 | BP | positive regulation of calcium ion transport into cytosol | Any process that increases the rate of the directed movement of calcium ions into the cytosol of a cell. The cytosol is that part of the cytoplasm that does not contain membranous or particulate subcellular components. |
CD4, ADCYAP1R1, CAV1, TRPC3, P2RX4 |
GO:0010529 | BP | negative regulation of transposition | Any process that decreases the frequency, rate or extent of transposition. Transposition results in the movement of discrete segments of DNA between nonhomologous sites. |
APOBEC3G, APOBEC3B |
GO:0010531 | BP | activation of JAK1 kinase activity | The process of introducing a phosphate group to a tyrosine residue of a JAK1 (Janus Activated Kinase 1) protein, thereby activating it. |
PIBF1 |
GO:0010534 | BP | regulation of activation of JAK2 kinase activity | Any process that modulates the frequency or rate of activation of JAK2 protein. The activation of JAK2 protein is the process of introducing a phosphate group to a tyrosine residue of a JAK2 (Janus Activated Kinase 2) protein, thereby activating it. |
SOCS1 |
GO:0010535 | BP | positive regulation of activation of JAK2 kinase activity | Any process that increase the frequency or rate of activation of JAK2 protein. The activation of JAK2 protein is the process of introducing a phosphate group to a tyrosine residue of a JAK2 (Janus Activated Kinase 2) protein, thereby activating it. |
AGT, GH1, CCL5 |
GO:0010543 | BP | regulation of platelet activation | Any process that modulates the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. |
SYK |
GO:0010544 | BP | negative regulation of platelet activation | Any process that decreases the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. |
F2, PDGFB, APOE, PDGFA, PDGFRA, NOS3, C1QTNF1 |
GO:0010557 | BP | positive regulation of macromolecule biosynthetic process | Any process that increases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. |
MTPN |
GO:0010559 | BP | regulation of glycoprotein biosynthetic process | Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of glycoproteins, any protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide. |
BCL2 |
GO:0010560 | BP | positive regulation of glycoprotein biosynthetic process | Any process that increases the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of glycoproteins, any protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide. |
IGF1 |
GO:0010564 | BP | regulation of cell cycle process | Any process that modulates a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. |
SOX9, HMGA2, SFRP1, TXLNG |
GO:0010565 | BP | regulation of cellular ketone metabolic process | Any process that modulates the chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups. |
PDK4 |
GO:0010569 | BP | regulation of double-strand break repair via homologous recombination | Any process that modulates the frequency, rate or extent of the error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. |
CHEK1, KDM1A, PPP4C, RAD51, SPIDR, RAD51AP1, TEX15 |
GO:0010571 | BP | positive regulation of nuclear cell cycle DNA replication | Any process that activates or increases the frequency, rate or extent of The DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle. |
CDC7, WIZ, ATRX, DBF4B |
GO:0010572 | BP | positive regulation of platelet activation | Any process that increases the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. |
TLR4 |
GO:0010573 | BP | vascular endothelial growth factor production | The appearance of vascular endothelial growth factor production due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. |
HIF1A, ADGRG1 |
GO:0010574 | BP | regulation of vascular endothelial growth factor production | Any process that modulates the frequency, rate, or extent of production of vascular endothelial growth factor. |
IL6, CCL2, NDRG2 |
GO:0010575 | BP | positive regulation of vascular endothelial growth factor production | Any process that increases or activates the frequency, rate, or extent of production of vascular endothelial growth factor. |
C3, TGFB1, IL1A, IL1B, ATF4, C5AR1, ARNT, ADORA2B, PTGS2, RORA, FLT4, BRCA1, IL6ST, GATA4, HIF1A, CYP1B1, CCBE1, SULF2, SULF1, HPSE |
GO:0010579 | BP | positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway | Any process that increases the frequency, rate or extent of adenylate cyclase (AC) activity that is an integral part of a G-protein coupled receptor signaling pathway. |
ADGRD1, GPER1 |
GO:0010586 | BP | miRNA metabolic process | The chemical reactions and pathways involving miRNA, microRNA, a class of single-stranded RNA molecules of about 21-23 nucleotides in length, which regulates gene expression. |
BCDIN3D, AGO4, AGO2 |
GO:0010587 | BP | miRNA catabolic process | The chemical reactions and pathways resulting in the breakdown of miRNA, microRNA, a class of single-stranded RNA molecules of about 21-23 nucleotides in length, which regulates gene expression. |
LIN28A |
GO:0010591 | BP | regulation of lamellipodium assembly | Any process that modulates the rate, frequency or extent of the formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell. |
CAPZB, SSH2, SSH3 |
GO:0010592 | BP | positive regulation of lamellipodium assembly | Any process that increases the rate, frequency or extent of the formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell. |
ARPC2, HSP90AA1, RAC2, HDAC4, RAC1, FSCN1, TWF2, WASF2 |
GO:0010593 | BP | negative regulation of lamellipodium assembly | Any process that decreases the rate, frequency or extent of the formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell. |
SLIT2 |
GO:0010594 | BP | regulation of endothelial cell migration | Any process that modulates the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium. |
EMP2, PTK2, BMPER, SEMA4A |
GO:0010595 | BP | positive regulation of endothelial cell migration | Any process that increases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium. |
ITGB1BP1, NRP1, NRP2, ROCK2, PDCD6, AGT, ITGB3, EDN1, THBS1, SPARC, ANXA3, BMP4, TDGF1, ETS1, VEGFA, PRKCA, FLT4, WNT5A, RHOB, GPLD1, TEK, BMPR2, PRKD1, ANGPT1, CCBE1, SCARB1, PROX1, ATOH8, PRKD2, FOXP1, ZNF580 |
GO:0010596 | BP | negative regulation of endothelial cell migration | Any process that decreases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium. |
KRIT1, SLIT2, BMP10, APOH, DCN, THBS1, SP100, NR2F2, PTPRM, SERPINF1, STC1, SYNJ2BP, DLL4 |
GO:0010603 | BP | regulation of cytoplasmic mRNA processing body assembly | Any process that modulates the rate, frequency, or extent of the aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic mRNA processing body. |
ATXN2L |
GO:0010606 | BP | positive regulation of cytoplasmic mRNA processing body assembly | Any process that increases the rate, frequency, or extent of the aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic mRNA processing body. |
CNOT1, PAN3, CNOT6 |
GO:0010608 | BP | posttranscriptional regulation of gene expression | Any process that modulates the frequency, rate or extent of gene expression after the production of an RNA transcript. |
PER1, ACE, MATR3, CAV1, PUM1, CDC37, GCNT2, PUM2, NANOS1, RC3H2 |
GO:0010609 | BP | mRNA localization resulting in posttranscriptional regulation of gene expression | Any process that modulates the frequency, rate or extent of gene expression after the production of a mRNA transcript by its transport into, or maintainance in, a specific location within the cell. |
MEX3D |
GO:0010611 | BP | regulation of cardiac muscle hypertrophy | Any process that modulates the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division. |
AKAP13, LMCD1 |
GO:0010613 | BP | positive regulation of cardiac muscle hypertrophy | Any process that increases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division. |
PDE5A, PDE9A, BMP10, AGT, IGF1, EDN1, PARP1, PRKCA, IL6ST, MTPN, MEF2A, CAMK2D, NR4A3 |
GO:0010614 | BP | negative regulation of cardiac muscle hypertrophy | Any process that decreases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division. |
BMP10, RGS2, GSK3B, SMAD4, P2RX4 |
GO:0010621 | BP | negative regulation of transcription by transcription factor localization | Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-dependent transcription using a mechanism that involves the localization of a transcription factor. |
ID1, HHEX |
GO:0010623 | BP | programmed cell death involved in cell development | The activation of endogenous cellular processes that result in the death of a cell as part of its development. |
NTRK1 |
GO:0010626 | BP | negative regulation of Schwann cell proliferation | Any process that decreases the frequency or extent of the multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system. |
SKI, DICER1 |
GO:0010628 | BP | positive regulation of gene expression | Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form. |
TLR4, PIK3CD, DDX3X, PDCD5, MUSK, PLSCR1, TLR3, KDM6A, KLF4, SPRY2, PARK2, TLR2, MITF, ROCK2, ZPR1, TADA3, ALDH1A2, KRAS, PDGFB, LDLR, TGFB1, NGF, INS, TNF, IL1A, IL1B, CRP, FN1, PF4, AMH, APOB, MYCN, TP53, IL6, CDK1, INHBA, VIM, CTSH, HSPA1A, HSPA1B, CCL3, AR, KIT, CD28, VDR, BMP2, EZR, CD46, VEGFA, IL7R, GJA1, ATF4, ERBB3, TNC, MT3, ITGA3, ITGB8, DNMT1, CALR, CTGF, ERP29, AVPR2, FGF9, PHB, RDX, BRCA1, STAT3, ID1, PIK3CB, PTGFR, NKX2-1, MAPK8, MAPK9, LIMS1, SLC11A1, PPM1F, STAR, SERPINB9, RAB27A, HMGA2, PRKAG1, WNT3, PLP1, CDC42, TGFB2, ACTA2, ACTG2, ACTC1, SRPK2, SMAD3, CDK6, HNRNPU, MDM2, E2F1, ANK2, ID2, MAP2K1, POU3F1, CAV1, TLE1, MEF2C, CNTN1, ANK3, GAS6, RAB3GAP1, RPS6KA2, TMED2, NR0B2, TWIST1, SMAD1, MAPK14, NTRK2, NFIL3, HIF1A, HFE, SFRP4, PID1, IQGAP3, LILRB1, CTCFL, OSR1, FUBP1, PAWR, SEC16B, QKI, GPER1, OLFM1, CITED1, CITED2, RBM4B, PDCD10, C1QTNF1, TRIM6, EPB41L4B, RGCC, TRPV4, DLL4, CYP26B1, DNMT3B, KDM5B, ZNF580, RIMS2, LAMP3, PTPN22, WNT6, NCOA3 |
GO:0010629 | BP | negative regulation of gene expression | Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form. |
WWP2, ACACB, KLF4, PARK2, STC2, FGF19, PDGFB, LDLR, TGFB1, TNF, CRYAB, ESR1, FYN, RB1, PGR, CCL3, CD28, PC, ACE, MIF, CCNB1, CD46, NME1, GJA1, NFKB1, YY1, ITGB8, RBL1, CTGF, ERP29, AKT1, MAP2K2, ACVR1B, SERPINF1, CDKN1A, XDH, CDC42, TGFB2, RACK1, TMF1, ID2, MAP2K1, REL, MEF2C, AES, TARDBP, PICALM, HDAC1, DIP2A, NR0B2, RNASEH2B, PLAG1, IQGAP3, SFRP1, FLCN, ZNF503, MYADM, GPER1, OLFM1, CITED2, NDFIP1, UPK3B, PDCD10, BBS2, PINK1, TRIM6, MKKS, SLC35C2, DLL4, NDFIP2, TBK1, CNOT7, NOCT, SNX12, ZNF148, CNPY2, PTPN22 |
GO:0010631 | BP | epithelial cell migration | The orderly movement of an epithelial cell from one site to another, often during the development of a multicellular organism. |
PKN1, PKN2, NANOS1 |
GO:0010632 | BP | regulation of epithelial cell migration | Any process that modulates the frequency, rate or extent of epithelial cell migration. |
ARSB, PTK2, CORO1C, MACF1 |
GO:0010633 | BP | negative regulation of epithelial cell migration | Any process that stops, prevents, or reduces the frequency, rate or extent of epithelial cell migration. |
PTPRG, PBLD, SEMA3A, ADIPOR1, MARVELD3, EVL, CORO1C |
GO:0010634 | BP | positive regulation of epithelial cell migration | Any process that activates or increases the frequency, rate or extent of epithelial cell migration. |
JUN, PFN1, CTSH, ITGA2, ITGA3, TGFBR2, SOX9, PPM1F, INSL3, TGFB2, RAB11A, ENPP2, BMPR2, HIF1A, GLIPR2, DOCK5, HDAC6 |
GO:0010635 | BP | regulation of mitochondrial fusion | Any process that modulates the frequency, rate or extent of merging of two or more mitochondria within a cell to form a single compartment. |
PID1 |
GO:0010636 | BP | positive regulation of mitochondrial fusion | Any process that increases the frequency, rate or extent of merging of two or more mitochondria within a cell to form a single compartment. |
PARK2, OPA1 |
GO:0010637 | BP | negative regulation of mitochondrial fusion | Any process that decreases the frequency, rate or extent of merging of two or more mitochondria within a cell to form a single compartment. |
PARK2, BNIP3, OMA1 |
GO:0010638 | BP | positive regulation of organelle organization | Any process that increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle. |
SURF4 |
GO:0010640 | BP | regulation of platelet-derived growth factor receptor signaling pathway | Any process that modulates the frequency, rate or extent of the platelet-derived growth factor receptor signaling pathway. |
LRIG2 |
GO:0010642 | BP | negative regulation of platelet-derived growth factor receptor signaling pathway | Any process that stops, prevents, or reduces the frequency, rate or extent of the platelet-derived growth factor receptor signaling pathway. |
APOD, SNCA, PTPRJ, ADIPOQ, NDRG4 |
GO:0010643 | BP | cell communication by chemical coupling | The process that mediates signaling interactions between one cell and another cell by the transfer of small, water-soluble molecules or metabolites between their adjacent cytoplasms via intercellular protein channels. |
GJA1, GJA5, DBN1 |
GO:0010644 | BP | cell communication by electrical coupling | The process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels. |
GJA1, KCNA1, DBN1 |
GO:0010649 | BP | regulation of cell communication by electrical coupling | Any process that modulates the frequency, rate or extent of cell communication via electrical coupling. Cell communication via electrical coupling is the process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels. |
SRI, CAMK2D |
GO:0010650 | BP | positive regulation of cell communication by electrical coupling | Any process that increases the frequency, rate or extent of cell communication via electrical coupling. Cell communication via electrical coupling is the process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels. |
ANK3 |
GO:0010652 | BP | positive regulation of cell communication by chemical coupling | Any process that increases the frequency, rate or extent of cell communication via chemical coupling. Cell communication by chemical coupling is the process that mediates signaling interactions between one cell and another cell by the transfer of small, water-soluble molecules or metabolites between their adjacent cytoplasms via intercellular protein channels. |
GJA1, GJA5 |
GO:0010656 | BP | negative regulation of muscle cell apoptotic process | Any process that decreases the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death. |
HMOX1 |
GO:0010657 | BP | muscle cell apoptotic process | A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a muscle cell and result in its death. A muscle cell is a mature contractile cell, commonly known as a myocyte, that forms one of three kinds of muscle. |
DMPK |
GO:0010659 | BP | cardiac muscle cell apoptotic process | A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a cardiac muscle cell and result in its death. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. |
NOL3, HSP90AA1, GNB1, RPS6KA2 |
GO:0010664 | BP | negative regulation of striated muscle cell apoptotic process | Any process that increases the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death. |
HMGCR |
GO:0010666 | BP | positive regulation of cardiac muscle cell apoptotic process | Any process that increases the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death. |
AGT, HMGCR, CXCR2, LTK, BNIP3, CAMK2D, MAP3K5 |
GO:0010667 | BP | negative regulation of cardiac muscle cell apoptotic process | Any process that decreases the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death. |
JAK2, NOL3, HSF1, ILK |
GO:0010668 | BP | ectodermal cell differentiation | The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an ectodermal cell. Differentiation includes the processes involved in commitment of a cell to a specific fate. |
ITGAM, ITGA6, VPS52 |
GO:0010669 | BP | epithelial structure maintenance | A tissue homeostatic process required for the maintenance of epithelial structure. |
LDB2, CXADR, CROCC, MKS1 |
GO:0010693 | BP | negative regulation of alkaline phosphatase activity | Any process that decreases the frequency, rate or extent of alkaline phosphatase activity, the catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum. |
TNF, TGFB2 |
GO:0010694 | BP | positive regulation of alkaline phosphatase activity | Any process that increases the frequency, rate or extent of alkaline phosphatase activity, the catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum. |
ITGA2, GPLD1, SMAD3, MEF2C, PPARGC1B |
GO:0010698 | MF | acetyltransferase activator activity | Binds to and increases the activity of an acetyltransferase, an enzyme which catalyzes the transfer of an acetyl group to an acceptor molecule. |
PDCD5 |
GO:0010700 | BP | negative regulation of norepinephrine secretion | Any process that decreases the frequency, rate or extent of the regulated release of norepinephrine. |
ADRA2B, AGTR2 |
GO:0010701 | BP | positive regulation of norepinephrine secretion | Any process that increases the frequency, rate or extent of the regulated release of norepinephrine. |
OXTR |