| GO ID | Ontology | GO Term | Term Definition |
Proteins |
GO:0009817 | BP | defense response to fungus, incompatible interaction | A response of an organism to a fungus that prevents the occurrence or spread of disease. |
TGFB1 |
GO:0009820 | BP | alkaloid metabolic process | The chemical reactions and pathways involving alkaloids, nitrogen containing natural products which are not otherwise classified as peptides, nonprotein amino acids, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones or primary metabolites (such as purine or pyrimidine bases). |
CYP2D6 |
GO:0009822 | BP | alkaloid catabolic process | The chemical reactions and pathways resulting in the breakdown of alkaloids, nitrogen containing natural products not otherwise classified as peptides, nonprotein amino acids, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones or primary metabolites (such as purine or pyrimidine bases). |
CYP3A4, CYP2D6, CYP3A5 |
GO:0009838 | BP | abscission | The controlled shedding of a body part. |
IST1, SPG20, AURKB, ZFYVE19 |
GO:0009841 | CC | mitochondrial endopeptidase Clp complex | A Clp endopeptidase complex located in the mitochondrion. |
CLPX |
GO:0009855 | BP | determination of bilateral symmetry | The establishment of an organism's body plan or part of an organism with respect to a single longitudinal plane. The pattern can either be symmetric, such that the halves are mirror images, or asymmetric where the pattern deviates from this symmetry. |
ALDH1A2 |
GO:0009880 | BP | embryonic pattern specification | The process that results in the patterns of cell differentiation that will arise in an embryo. |
LRP6, FGFR2, SMAD3, ZBTB16, SIM2, ERBB4, SMAD1, PGAP1, DISP1, SMAD5 |
GO:0009881 | MF | photoreceptor activity | The function of absorbing and responding to incidental electromagnetic radiation, particularly visible light. The response may involve a change in conformation. |
OPN3 |
GO:0009882 | MF | blue light photoreceptor activity | The function of absorbing and responding to electromagnetic radiation with a wavelength of approximately 400-470nm. The response may involve a change in conformation. |
CRY1 |
GO:0009887 | BP | animal organ morphogenesis | Morphogenesis of an animal organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. |
ABLIM1, NRP1, TNFSF11, EREG, PAX4, GMNN, PDGFA, TH, DCN, FGF2, BMP2, CCL2, ITGA2, ITGAX, COL9A1, FGFR2, STX2, COL18A1, SYK, CRKL, COMP, VEGFC, GSK3B, EFNB2, HCCS, NLRP5, RELA, NOTCH2, TLE1, TLE3, AES, EP300, PTCH1, FHL1, DGCR6, TMEM176B, PHLDA2, NEK8, SMARCC1, SEMA6A, PDGFC, TRPS1, EVL |
GO:0009888 | BP | tissue development | The process whose specific outcome is the progression of a tissue over time, from its formation to the mature structure. |
NR5A2, MBD3, GAA, WT1, DHCR24, TNFRSF19, TRPS1, CNPY2 |
GO:0009890 | BP | negative regulation of biosynthetic process | Any process that stops, prevents, or reduces the rate of the chemical reactions and pathways resulting in the formation of substances. |
GSTP1 |
GO:0009893 | BP | positive regulation of metabolic process | Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism. |
PIGA |
GO:0009897 | CC | external side of plasma membrane | The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface. |
IGLL5, TLR4, SEMA7A, GPC4, ABCA1, CLPTM1, GSR, ADA, LDLR, TNF, CD4, FGA, FGB, FGG, TFRC, CD74, SERPINA5, IL6, ICAM1, ITGB1, ITGAV, P4HB, THBS1, PTPRC, ITGA5, ANXA5, KIT, CD28, LAMP1, ACE, NCAM1, SELL, SLC2A4, B4GALT1, CD36, IL7R, ITGA2, LAG3, SDC1, VCAM1, CD33, S1PR1, CD9, ITGA6, FAS, ITGA3, CD27, CALR, CD40LG, CDH5, CHRNA7, BMPR1A, TGFBR2, ITGAE, IL6ST, IL12RB1, ECE1, MCAM, CXCL12, BCAM, SCNN1G, CLCN3, EPHA5, CDH13, ANTXR2, B2M, CD83, IL1RL1, NRG1, TGFBR3, MFGE8, ALCAM, ADGRE1, SPA17, HFE, AMOT, CD276, VTCN1, RTN4RL1, PDPN, ADGRA3, SCUBE1, NLGN1, TRPV1, LILRB1, STAB2, NRCAM, MAP3K5, CD244, HEG1, TFR2, TNFRSF11A |
GO:0009898 | CC | cytoplasmic side of plasma membrane | The leaflet the plasma membrane that faces the cytoplasm and any proteins embedded or anchored in it or attached to its surface. |
TH, KIT, G6PD, JUP, GM2A, ATP2B1, PTPN4, MAP2K2, RGS2, GEM, PTEN, DLG1, LDLRAP1, PTP4A1, PKP4, ASPSCR1, CHMP4B, RAB21, PTPN22 |
GO:0009912 | BP | auditory receptor cell fate commitment | The process in which the cellular identity of auditory hair cells is acquired and determined. |
NOTCH1 |
GO:0009913 | BP | epidermal cell differentiation | The process in which a relatively unspecialized cell acquires specialized features of an epidermal cell, any of the cells making up the epidermis. |
KLF4, HDAC1, HDAC2 |
GO:0009917 | MF | sterol 5-alpha reductase activity | Catalysis of the removal of a C-5 double bond in the B ring of a sterol. |
SRD5A2 |
GO:0009922 | MF | fatty acid elongase activity | Catalysis of the reaction: fatty acid (C-16 or longer) + 2-C = fatty acid (C-16 or longer + 2-C). |
ELOVL7, ELOVL1, ELOVL4, ELOVL6, ELOVL5 |
GO:0009925 | CC | basal plasma membrane | The region of the plasma membrane located at the basal end of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis. |
MYO1C, CLDN4, TF, MET, ITGA6, EPS15, TEK, DST, ANK3, PKD2, ITGA9, BMPR2, LDLRAP1, MUC20, SLC23A2 |
GO:0009931 | MF | calcium-dependent protein serine/threonine kinase activity | Catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; and ATP + a protein threonine = ADP + protein threonine phosphate. These reactions are dependent on the presence of calcium ions. |
MAPKAPK2, MKNK1, MKNK2 |
GO:0009948 | BP | anterior/posterior axis specification | The establishment, maintenance and elaboration of the anterior/posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism. |
AURKA, BMP4, SKI, CTNNB1, WNT3, WLS, PGAP1 |
GO:0009950 | BP | dorsal/ventral axis specification | The establishment, maintenance and elaboration of the dorsal/ventral axis. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism. |
AXIN1, CTNNB1, BMPR1A, WNT3, SFRP1, MDFI |
GO:0009952 | BP | anterior/posterior pattern specification | The regionalization process in which specific areas of cell differentiation are determined along the anterior-posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism. |
HOXA2, HOXA3, TBX1, LRP5, TULP3, ALDH1A2, HOXC4, HOXB5, GLI2, GLI3, NR2F2, YY1, ACVR2A, HOXD10, HOXA10, HOXA6, TGFBR1, PBX1, CRKL, BTG2, HHEX, EMX2, ZBTB16, RING1, GRSF1, ACVR2B, BMPR2, SMAD2, TSHZ1, ARC, PCSK5, HIPK2 |
GO:0009953 | BP | dorsal/ventral pattern formation | The regionalization process in which the areas along the dorsal/ventral axis are established that will lead to differences in cell differentiation. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism. |
HOXA2, EDN1, LHX2, PTCH1, DUSP6, DISP1, HHIP, FBXL15 |
GO:0009954 | BP | proximal/distal pattern formation | The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis. The proximal/distal axis is defined by a line that runs from main body (proximal end) of an organism outward (distal end). |
GREM1, ALDH1A2, GLI2, GLI3, HOXD10, HOXA10, CTNNB1, PBX1, PBX2, DLX2, CHSY1, CYP26B1 |
GO:0009956 | BP | radial pattern formation | The regionalization process that results in defined areas around a point in which specific types of cell differentiation will occur. |
NR2F2 |
GO:0009957 | BP | epidermal cell fate specification | The process in which a cell becomes capable of differentiating autonomously into an epidermal cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. |
PTCH1 |
GO:0009966 | BP | regulation of signal transduction | Any process that modulates the frequency, rate or extent of signal transduction. |
SOCS2, BIRC5, FURIN, TDGF1, NUP62, PPP1R2, NCLN, VWCE, MGLL, TSPYL2, CDC42SE2, GLRX2 |
GO:0009967 | BP | positive regulation of signal transduction | Any process that activates or increases the frequency, rate or extent of signal transduction. |
SOCS2, IRS4, ARHGAP6, SKAP2, PTH, CHN1, SH3BGR, ADAMTS20, GRB2, KHDRBS1, EPS8, GRB14, SHB, ADIPOQ, LDLRAP1, HOMER1, BLNK, STAM, SORBS1, SH2B1, PAG1, CDKN2AIP, ITSN2, HDAC6, VAV3, MAPK8IP1, SH2B3 |
GO:0009968 | BP | negative regulation of signal transduction | Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction. |
RGS12, RGS5, RGS10, SOCS5, IGFBP3, ERBB3, RGS7, ACVR1, RGS7BP, RGS22, UBASH3B, INPP5D, HHIP, PAK1IP1 |
GO:0009972 | BP | cytidine deamination | The removal of amino group in the presence of water. |
APOBEC3G |
GO:0009982 | MF | pseudouridine synthase activity | Catalysis of the reaction: RNA uridine = RNA pseudouridine. Conversion of uridine in an RNA molecule to pseudouridine by rotation of the C1'-N-1 glycosidic bond of uridine in RNA to a C1'-C5. |
DKC1, RPUSD3, TRUB1, RPUSD4, PUS7, PUS3 |
GO:0009986 | CC | cell surface | The external part of the cell wall and/or plasma membrane. |
TLR4, ADAM10, NRP1, PLXNB2, CAPN5, NRDC, TYROBP, FZD6, GREM1, TLR2, SRPX2, RAMP1, RAMP3, SDC3, HMMR, ENTPD6, VAMP4, LRP6, CLSTN1, CSPG5, MPZL1, BMP10, GOT2, EGFR, PLG, PLAU, PLAT, ADA, PDGFB, LDLR, TGFA, TGFB1, TNF, HLA-B, HLA-DRA, CRYAB, APOA1, FGA, FGB, FGG, APOH, AMBP, TFRC, TF, ANXA1, PDGFA, PRNP, CD74, NTRK1, APP, ITGB3, ITGB2, ICAM1, ITGB1, ITGAV, LPL, CSF1R, ANXA2, HSP90AA1, THBS1, NGFR, CD55, SLC3A2, HSP90AB1, PTPRC, MET, MFI2, ITGA5, IL6R, LGALS1, HMGB1, SPARC, ANXA4, PDGFRB, FURIN, TFPI, CD28, HSPD1, CLU, GHR, HSPA5, ITGAM, MBL2, RALA, DMD, IGF2R, BMP2, TDGF1, CFTR, NCAM1, PDIA4, HLA-E, MIF, CPM, IDE, IL1R1, PVR, FOLR1, AREG, CD46, VEGFA, CD1D, ARSB, TIMP2, CD44, ITGB4, EPCAM, PRLR, CD36, ITGA2, CR1, ITGB5, SDC1, PAM, CD58, VCAM1, CD53, HLA-DPA1, ITGAX, NT5E, C5AR1, FGFR2, BGN, FUT4, ENPP1, CA4, MRC1, ITGA6, TNFSF4, CXCR2, CD24, F2R, FAS, ITGA3, ITGB8, ACVR2A, DPP4, CALR, PCSK6, CD40LG, ERP29, PDIA3, HLA-A, HLA-F, SLC6A1, LRPAP1, SDC4, CDH5, SDC2, PHB, ACVR1B, TGFBR1, WNT5A, ADCYAP1R1, SLC1A3, SLC1A2, SLC1A4, NOTCH1, SLC11A2, PSEN1, MMP16, CLCN3, VAMP7, EPHA4, EMP2, SYNJ2BP, CXCR4, CXADR, ADAM8, ADAM17, PKD1, NDP, HNRNPU, TEK, TGFBR3, NOTCH2, C1QBP, KCNA1, BST2, KCNH2, STX4, CDH17, GRIN2A, HYAL2, PTPRJ, ANK3, SLC39A6, ADAM9, IQGAP2, BMPR2, DSG2, DIP2A, PTPRK, VAMP3, ADIPOQ, AOC3, MICB, MICA, ANO6, SFRP4, CSPG4, RTN4RL1, LRRC8A, SULF2, SULF1, SCUBE1, SCUBE3, NLGN4X, NLGN1, SFRP1, PCSK9, TSPAN14, CYP2W1, HM13, ADAMTS15, DEFB104A, SCARB1, GPR98, TNR, GHSR, KISS1R, SLC46A1, DCBLD2, HHIP, HBEGF, PHB2, ERP44, SLC46A2, ULBP2, WNT5B, CLSTN2, C10orf54, TMEM206, TRPV4, RC3H2, TNS1, ROBO2, APMAP, CD209, TNFRSF12A, CD93, PDGFC, IL17RB, CLDND1, GPRC5B, ADAMTS9, ADAMTS7, NRXN1, INTU, FZD4, PROCR, SLC7A11, TLN1, HILPDA, TRPV2, LIPG, WNT6 |
GO:0009987 | BP | cellular process | Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. |
APP, TUBB, MAP1B, HDGFL1 |
GO:0009988 | BP | cell-cell recognition | Cell recognition between cells. May involve the formation of specialized cell junctions. |
CD209 |
GO:0009991 | BP | response to extracellular stimulus | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an extracellular stimulus. |
NOCT |
GO:0009992 | BP | cellular water homeostasis | Any process involved in the maintenance of an internal steady state of water within a cell. |
AQP9, AQP8, MIP, AQP2, AQP3 |
GO:0009994 | BP | oocyte differentiation | The process in which a relatively unspecialized immature germ cell acquires the specialized features of a mature female gamete. |
LGR5, KMT2B |
GO:0010001 | BP | glial cell differentiation | The process in which a relatively unspecialized cell acquires the specialized features of a glial cell. |
NFIB, GAP43, CDH2, DNER, KLF15, MMP24 |
GO:0010002 | BP | cardioblast differentiation | The process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. |
TGFB2 |
GO:0010008 | CC | endosome membrane | The lipid bilayer surrounding an endosome. |
VPS37C, TLR4, RHOD, GOLIM4, AP3D1, LEPROT, ATP6V0E1, TLR3, IRAK2, MAP3K7, SNX3, VPS4B, VPS26A, AP1G2, EGFR, LDLR, HLA-DQA2, HLA-DQA1, HLA-DQB1, TF, APOB, ERBB2, INSR, CD14, UBC, LAMP1, HLA-DOB, CD1D, HLA-DPA1, RAB5A, UBA1, MRC1, CD68, RAB7A, IRAK1, CLCN4, CLCN5, CLCN6, ANTXR2, UBE2D3, ATP6V0D1, RHOB, RPS27A, UBA52, CD164, TCIRG1, SNX1, GRB14, ACAP2, NCF4, TAB1, NTRK2, WDR44, WIPI1, PARM1, RABEPK, VPS52, TAB3, COMMD1, APPL2, VPS37A, TPCN2, RFFL, TBC1D5, ATP6V0A1, PMEPA1, TMBIM1, VPS35, SNX18, TM9SF2, NDFIP1, TMEM165, ABCB6, VTA1, CD320, EHD3, ANKFY1, VPS29, SUN2, LAMTOR3, TBK1, LAMP5, GGA2, GGA1, RAB22A, RAB23, ITM2B, PIKFYVE, LAMTOR2 |
GO:0010021 | BP | amylopectin biosynthetic process | The chemical reactions and pathways resulting in the formation of amylopectin, the (1->4) linked alpha glucose units with alpha-(1->6) linkages. |
SLC2A4 |
GO:0010025 | BP | wax biosynthetic process | The chemical reactions and pathways resulting in the formation of wax, which includes C16 and C18 fatty acids. |
FAR2 |
GO:0010032 | BP | meiotic chromosome condensation | Compaction of chromatin structure prior to meiosis in eukaryotic cells. |
SMC2, NCAPD3, NCAPD2, SMC4 |
GO:0010033 | BP | response to organic substance | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus. |
SUPT5H, AQP9, ANXA5, CREB1, GART, S100P, PPP2R1A, TIMP3, WNT5A, CTSC, RELA, SQLE, GLRX2, HDAC6 |
GO:0010035 | BP | response to inorganic substance | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inorganic substance stimulus. |
GART, EEF1A2 |
GO:0010038 | BP | response to metal ion | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus. |
MT2A, MT3, MT1X, MTF1, NDRG1, NEDD4L |
GO:0010039 | BP | response to iron ion | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus. |
APBB1, C1QA, BCL2, ALAD, DRD2, CPOX, SLC11A2, ABAT, HAMP, MDM2, FXN, HFE, CYBRD1, TFR2 |
GO:0010040 | BP | response to iron(II) ion | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron(II) ion stimulus. |
SNCA |
GO:0010041 | BP | response to iron(III) ion | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron(III) ion stimulus. |
CYP1A1, G6PD |
GO:0010042 | BP | response to manganese ion | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a manganese ion stimulus. |
TSPO, PTGS2, ADAM9 |
GO:0010043 | BP | response to zinc ion | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a zinc ion stimulus. |
CA2, ASS1, BGLAP, S100A8, TH, ALAD, VCAM1, PLN, PTEN, HAMP, SLC30A8, GGH, SLC30A1 |
GO:0010044 | BP | response to aluminum ion | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aluminum ion stimulus. |
QDPR, ALAD, MAOB |
GO:0010045 | BP | response to nickel cation | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nickel cation stimulus. |
CACNA1G |
GO:0010046 | BP | response to mycotoxin | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mycotoxin stimulus. A mycotoxin is a toxic chemical substance produced by fungi. |
ASS1 |
GO:0010106 | BP | cellular response to iron ion starvation | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of iron ions. |
HFE |
GO:0010107 | BP | potassium ion import | The directed movement of potassium ions into a cell or organelle. |
ATP1B1, ATP1A2, ATP12A, ATP1B3, KCNJ12, KCNJ11 |
GO:0010133 | BP | proline catabolic process to glutamate | The chemical reactions and pathways resulting in the breakdown of proline into other compounds, including glutamate. |
PRODH |
GO:0010155 | BP | regulation of proton transport | Any process that modulates the frequency, rate or extent of proton transport into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
NOX5 |
GO:0010157 | BP | response to chlorate | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chlorate stimulus. |
PTCH1 |
GO:0010159 | BP | specification of organ position | The regionalization process in which information that determines the correct position at which organ primordia are formed is generated and perceived resulting in correct positioning of the new organ. |
HOXA3, BMP4 |
GO:0010164 | BP | response to cesium ion | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cesium stimulus. |
CYP2R1 |
GO:0010165 | BP | response to X-ray | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of X-ray radiation. An X-ray is a form of electromagnetic radiation with a wavelength in the range of 10 nanometers to 100 picometers (corresponding to frequencies in the range 30 PHz to 3 EHz). |
ANXA1, TP53, ERCC1, CDKN1A, MSH2, BRCC3, BRCA2, BLM, RAD51, XRCC4, PMAIP1, IKBIP |
GO:0010172 | BP | embryonic body morphogenesis | The process in which the anatomical structures of the embryonic soma are generated and organized. |
GREM2, IFT122 |
GO:0010181 | MF | FMN binding | Interacting selectively and non-covalently with flavin mono nucleotide. Flavin mono nucleotide (FMN) is the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes. |
CREG1, NOS3, DHODH, HAO2 |
GO:0010193 | BP | response to ozone | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ozone stimulus. |
CYP2E1, EDN1 |
GO:0010212 | BP | response to ionizing radiation | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ionizing radiation stimulus. Ionizing radiation is radiation with sufficient energy to remove electrons from atoms and may arise from spontaneous decay of unstable isotopes, resulting in alpha and beta particles and gamma rays. Ionizing radiation also includes X-rays. |
RAD51C, RAD51D, RNF8, ICAM1, ALAD, H2AFX, VCAM1, RRM1, BRCA1, BRCC3, STAR, CLK2, MTA1, STK11, INTS3, RFWD3, BRAT1, CYP2R1, LZIC, TOPBP1, RAD54L, NABP1, USP28, DCLRE1C, NABP2, INIP, DNMT3B |
GO:0010216 | BP | maintenance of DNA methylation | Any process involved in maintaining the methylation state of a nucleotide sequence. |
DNMT1, UHRF2, UHRF1, HELLS |
GO:0010224 | BP | response to UV-B | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-B radiation stimulus. UV-B radiation (UV-B light) spans the wavelengths 280 to 315 nm. |
BCL2, IL12A, MSH2, XPC, RELA |
GO:0010225 | BP | response to UV-C | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-C radiation stimulus. UV-C radiation (UV-C light) spans the wavelengths 100 to 280 nm. |
BCL3, YY1, BRCA2, POLH, MAP3K4 |
GO:0010226 | BP | response to lithium ion | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lithium (Li+) ion stimulus. |
IGFBP2, PTGS2, ASCL1, EIF2B5 |
GO:0010232 | BP | vascular transport | The directed movement of substances, into, out of or within a cell, either in a vascular tissue or in the vascular membrane. |
GJA1 |
GO:0010243 | BP | response to organonitrogen compound | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organonitrogen stimulus. An organonitrogen compound is formally a compound containing at least one carbon-nitrogen bond. |
MGST3, ABCC4, CYP2E1, MGST1, CDKN1A, NNMT, MGST2 |
GO:0010248 | BP | establishment or maintenance of transmembrane electrochemical gradient | The directed movement of ions to establish or maintain an electrochemical gradient across a membrane by means of some agent such as a transporter or pore. |
SLC22A1, ATP1B1, ATP1A2, ATP12A, ATP1B3, BAX |
GO:0010256 | BP | endomembrane system organization | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endomembrane system. |
ARFGEF2 |
GO:0010259 | BP | multicellular organism aging | An aging process that has as participant a whole multicellular organism. Multicellular organism aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Multicellular organisms aging includes processes like cellular senescence and organ senescence, but is more inclusive. May precede death (GO:0016265) of an organism and may succeed developmental maturation (GO:0021700). |
NDUFS6, EDN1, TH, ERCC1, SLC1A2, HYAL2, RNF165, CISD2, SEC63 |
GO:0010260 | BP | animal organ senescence | The process that occurs in an animal organ near the end of its active life that is associated with the dismantling of cell components and membranes, and an overall decline in metabolism. |
ERO1A |
GO:0010265 | BP | SCF complex assembly | The aggregation, arrangement and bonding together of a set of components to form the SKP1-Cullin/Cdc53-F-box protein ubiquitin ligase (SCF) complex. |
CAND1 |
GO:0010266 | BP | response to vitamin B1 | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B1 stimulus. |
ALAD, TSPO |
GO:0010269 | BP | response to selenium ion | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from selenium ion. |
APOB, RPLP0, GPX1, ALAD, MAOB |
GO:0010273 | BP | detoxification of copper ion | Any process that reduces or removes the toxicity of copper ion. These include transport of copper away from sensitive areas and to compartments or complexes whose purpose is sequestration of copper ion. |
MT1X |
GO:0010288 | BP | response to lead ion | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lead ion stimulus. |
PTH, APP, QDPR, SPARC, CDK4, SLC6A1, CPOX, STAR |
GO:0010309 | MF | acireductone dioxygenase [iron(II)-requiring] activity | Catalysis of the reaction: 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + O(2) = 4-methylthio-2-oxobutanoate + formate + H(+). |
ADI1 |
GO:0010310 | BP | regulation of hydrogen peroxide metabolic process | Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving hydrogen peroxide. |
RAC2, RAC1, NOXA1, PINK1 |
GO:0010314 | MF | phosphatidylinositol-5-phosphate binding | Interacting selectively and non-covalently with phosphatidylinositol-5-phosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 5' position. |
SH3PXD2B, SNX3, PLEKHA5, SNX24 |
GO:0010324 | BP | membrane invagination | The infolding of a membrane. |
CHMP2A, SNX3, FCHO2, FNBP1L |
GO:0010332 | BP | response to gamma radiation | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gamma radiation stimulus. Gamma radiation is a form of electromagnetic radiation (EMR) or light emission of a specific frequency produced from sub-atomic particle interaction, such as electron-positron annihilation and radioactive decay. Gamma rays are generally characterized as EMR having the highest frequency and energy, and also the shortest wavelength, within the electromagnetic radiation spectrum. |
TRIM13, MYC, TP53, GPX1, PARP1, BCL2, CCL2, BRCA2, POLG, PRKDC, BAX, FANCD2 |
GO:0010369 | CC | chromocenter | A region in which centric, heterochromatic portions of one or more chromosomes form a compact structure. |
OIP5, CBX5, CBX1, FMR1, CDCA8, ESCO2, MBD6, AURKB, MBD5 |
GO:0010385 | MF | double-stranded methylated DNA binding | Interacting selectively and non-covalently with double-stranded methylated DNA. Methylation of cytosine or adenine in DNA is an important mechanism for establishing stable heritable epigenetic marks. |
H2AFY, EGR1, WT1 |
GO:0010387 | BP | COP9 signalosome assembly | The aggregation, arrangement and bonding together of a set of components to form a COP9 signalosome. |
COPS8 |
GO:0010388 | BP | cullin deneddylation | The modification of cullins by removal of ubiquitin-like protein NEDD8 (RUB1). |
COPS6, COPS8, COPS7B |
GO:0010389 | BP | regulation of G2/M transition of mitotic cell cycle | Any process that modulates the rate or extent of progression from G2 phase to M phase of the mitotic cell cycle. |
CENPF, PKIA, CAMK2D, KIF14, RNASEH2B |
GO:0010390 | BP | histone monoubiquitination | The modification of histones by addition of a single ubiquitin group. |
RAG1, UBE2E1, UHRF1, WAC |
GO:0010424 | BP | DNA methylation on cytosine within a CG sequence | The covalent transfer of a methyl group to C-5 or N-4 of a cytosine located within a CG sequence in a DNA molecule. |
DNMT3B |
GO:0010428 | MF | methyl-CpNpG binding | Interacting selectively and non-covalently with a methylated cytosine/unspecified/guanine trinucleotide. |
ZBTB4 |
GO:0010430 | BP | fatty acid omega-oxidation | A fatty acid oxidation process in which the methyl group at the end of the fatty acid molecule (the omega carbon) is first oxidized to a hydroxyl group, then to an oxo group, and finally to a carboxyl group. The long chain dicarboxylates derived from omega-oxidation then enter the beta-oxidation pathway for further degradation. |
ADH7, CYP4V2 |
GO:0010447 | BP | response to acidic pH | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH < 7. pH is a measure of the acidity or basicity of an aqueous solution. |
CTSS, SERPINF1, ASIC2, ASIC3 |
GO:0010452 | BP | histone H3-K36 methylation | The modification of histone H3 by addition of one or more methyl groups to lysine at position 36 of the histone. |
WHSC1 |
GO:0010453 | BP | regulation of cell fate commitment | Any process that modulates the frequency, rate or extent of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field. |
BMP4, FGFR2 |