| GO ID | Ontology | GO Term | Term Definition |
Proteins |
GO:0006003 | BP | fructose 2,6-bisphosphate metabolic process | The chemical reactions and pathways involving fructose 2,6-bisphosphate. The D enantiomer is an important regulator of the glycolytic and gluconeogenic pathways. It inhibits fructose 1,6-bisphosphatase and activates phosphofructokinase. |
PFKFB2, PFKFB1, PFKFB3, PFKFB4 |
GO:0006004 | BP | fucose metabolic process | The chemical reactions and pathways involving fucose, or 6-deoxygalactose, which has two enantiomers, D-fucose and L-fucose. |
FUCA1, FUCA2 |
GO:0006006 | BP | glucose metabolic process | The chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. D-glucose is dextrorotatory and is sometimes known as dextrose; it is an important source of energy for living organisms and is found free as well as combined in homo- and hetero-oligosaccharides and polysaccharides. |
SLC37A4, H6PD, INS, IGF2, TNF, APOD, BPGM, PDHA1, GAA, DLAT, PDHB, G6PD, IGFBP5, NPY1R, AKT1, AKT2, PCK1, PGM1, LEP, PIK3CA, GNPDA1, CPT1A, SORD, FABP5, CREM, PPARD, KCNJ11, PDK1, ADIPOQ, MAPK14, PDK4, BRAT1, DCXR, OMA1, PGM2, GHRL, NISCH, IRS2 |
GO:0006007 | BP | glucose catabolic process | The chemical reactions and pathways resulting in the breakdown of glucose, the aldohexose gluco-hexose. |
LRP5, BAD |
GO:0006011 | BP | UDP-glucose metabolic process | The chemical reactions and pathways involving UDP-glucose, uridinediphosphoglucose, a substance composed of glucose in glycosidic linkage with uridine diphosphate. |
UGDH, UGP2 |
GO:0006012 | BP | galactose metabolic process | The chemical reactions and pathways involving galactose, the aldohexose galacto-hexose. D-galactose is widely distributed in combined form in plants, animals and microorganisms as a constituent of oligo- and polysaccharides; it also occurs in galactolipids and as its glucoside in lactose and melibiose. |
GALT, B4GALT1, SLC35A2, GALK2, PPARGC1A |
GO:0006013 | BP | mannose metabolic process | The chemical reactions and pathways involving mannose, the aldohexose manno-hexose, the C-2 epimer of glucose. The D-(+)-form is widely distributed in mannans and hemicelluloses and is of major importance in the core oligosaccharide of N-linked oligosaccharides of glycoproteins. |
MAN2B1, MAN2A2, MAN2B2 |
GO:0006015 | BP | 5-phosphoribose 1-diphosphate biosynthetic process | The chemical reactions and pathways resulting in the formation of 5-phosphoribose 1-diphosphate, also known as 5-phosphoribosyl-1-pyrophosphate. |
PRPS2, PRPS1 |
GO:0006020 | BP | inositol metabolic process | The chemical reactions and pathways involving inositol, 1,2,3,4,5,6-cyclohexanehexol, a growth factor for animals and microorganisms. |
ITPKA, IMPA1, PPIP5K1 |
GO:0006021 | BP | inositol biosynthetic process | The chemical reactions and pathways resulting in the formation of inositol, 1,2,3,4,5,6-cyclohexanehexol, a growth factor for animals and microorganisms. |
IMPA1, ISYNA1 |
GO:0006024 | BP | glycosaminoglycan biosynthetic process | The chemical reactions and pathways resulting in the formation of glycosaminoglycans, any of a group of polysaccharides that contain amino sugars. |
HS3ST1, HS6ST1, UGDH, SDC3, GPC4, HEXA, PDGFRB, SDC1, SDC4, SDC2, GPC1, NDST1, HSPG2, EXT1, SLC35D2, HS2ST1, GALNT5, GCNT2, GPC2, PXYLP1, EXT2, HS6ST2, XYLT2, GPC6, HS3ST3B1 |
GO:0006027 | BP | glycosaminoglycan catabolic process | The chemical reactions and pathways resulting in the breakdown of glycosaminoglycans, any one of a group of polysaccharides that contain amino sugars. |
SDC3, GPC4, FUCA1, GNS, SDC1, SDC4, SDC2, GPC1, SGSH, NAGLU, HSPG2, HYAL2, HGSNAT, GPC2, HPSE, GPC6 |
GO:0006029 | BP | proteoglycan metabolic process | The chemical reactions and pathways involving proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans. |
COL11A1, BMP2, PPARD, HPSE |
GO:0006032 | BP | chitin catabolic process | The chemical reactions and pathways resulting in the breakdown of chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues. |
CTBS, CHIT1 |
GO:0006040 | BP | amino sugar metabolic process | The chemical reactions and pathways involving any amino sugar, sugars containing an amino group in place of a hydroxyl group. |
ST3GAL2 |
GO:0006043 | BP | glucosamine catabolic process | The chemical reactions and pathways resulting in the breakdown of glucosamine (2-amino-2-deoxyglucopyranose), an aminodeoxysugar that occurs in combined form in chitin. |
GNPDA1 |
GO:0006044 | BP | N-acetylglucosamine metabolic process | The chemical reactions and pathways involving N-acetylglucosamine. The D isomer is a common structural unit of glycoproteins in plants, bacteria and animals; it is often the terminal sugar of an oligosaccharide group of a glycoprotein. |
MGEA5, LARGE, CHST4, CHST5, CHST6, CHST7, CHST2 |
GO:0006045 | BP | N-acetylglucosamine biosynthetic process | The chemical reactions and pathways resulting in the formation of N-acetylglucosamine. The D isomer is a common structural unit of glycoproteins in plants, bacteria and animals; it is often the terminal sugar of an oligosaccharide group of a glycoprotein. |
GNE |
GO:0006046 | BP | N-acetylglucosamine catabolic process | The chemical reactions and pathways resulting in the breakdown of N-acetylglucosamine. The D isomer is a common structural unit of glycoproteins in plants, bacteria and animals; it is often the terminal sugar of an oligosaccharide group of a glycoprotein. |
GNPDA1 |
GO:0006047 | BP | UDP-N-acetylglucosamine metabolic process | The chemical reactions and pathways involving UDP-N-acetylglucosamine, a substance composed of N-acetylglucosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate. |
GFPT1, GNE, SLC35A3 |
GO:0006048 | BP | UDP-N-acetylglucosamine biosynthetic process | The chemical reactions and pathways resulting in the formation of UDP-N-acetylglucosamine, a substance composed of N-acetylglucosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate. |
GNPDA1, GFPT1, UAP1 |
GO:0006054 | BP | N-acetylneuraminate metabolic process | The chemical reactions and pathways involving N-acetylneuraminate, the anion of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid. |
ST6GAL1, ST3GAL1, CMAS, GNE |
GO:0006061 | BP | sorbitol biosynthetic process | The chemical reactions and pathways resulting in the formation of sorbitol (D-glucitol), one of the ten stereoisomeric hexitols. It can be derived from glucose by reduction of the aldehyde group. |
AKR1B1 |
GO:0006062 | BP | sorbitol catabolic process | The chemical reactions and pathways resulting in the breakdown of sorbitol (D-glucitol), one of the ten stereoisomeric hexitols. It can be derived from glucose by reduction of the aldehyde group. |
SORD |
GO:0006065 | BP | UDP-glucuronate biosynthetic process | The chemical reactions and pathways resulting in the formation of UDP-glucuronate, a substance composed of glucuronic acid in glycosidic linkage with uridine diphosphate. |
UGDH, UGP2, SLC35D1 |
GO:0006066 | BP | alcohol metabolic process | The chemical reactions and pathways involving alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom. |
ALDH2, ALDH3B2, DHRS4 |
GO:0006068 | BP | ethanol catabolic process | The chemical reactions and pathways resulting in the breakdown of ethanol, CH3-CH2-OH, a colorless, water-miscible, flammable liquid produced by alcoholic fermentation. |
ALDH2, ALDH1B1, ADH7, ALDH3B2 |
GO:0006069 | BP | ethanol oxidation | An ethanol metabolic process in which ethanol is converted to acetyl-CoA via acetaldehyde and acetate. |
ADH1B, ALDH1A1, ALDH2, ALDH1B1, ADH7, ACSS2, ACSS1 |
GO:0006071 | BP | glycerol metabolic process | The chemical reactions and pathways involving glycerol, 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids. |
GK, TKFC, COQ2, DGAT2, COQ3 |
GO:0006072 | BP | glycerol-3-phosphate metabolic process | The chemical reactions and pathways involving glycerol-3-phosphate, a phosphoric monoester of glycerol. |
GPD2 |
GO:0006081 | BP | cellular aldehyde metabolic process | The chemical reactions and pathways involving aldehydes, any organic compound with the formula R-CH=O, as carried out by individual cells. |
AKR7A2, ALDH1A1, ALDH9A1, ALDH7A1, ALDH3A2 |
GO:0006082 | BP | organic acid metabolic process | The chemical reactions and pathways involving organic acids, any acidic compound containing carbon in covalent linkage. |
FMO2 |
GO:0006084 | BP | acetyl-CoA metabolic process | The chemical reactions and pathways involving acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis. |
ACACB, FASN |
GO:0006085 | BP | acetyl-CoA biosynthetic process | The chemical reactions and pathways resulting in the formation of acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated. |
ACSS1 |
GO:0006086 | BP | acetyl-CoA biosynthetic process from pyruvate | The chemical reactions and pathways resulting in the formation of acetyl-CoA from pyruvate. |
PDHA1, DLAT, PDHB |
GO:0006089 | BP | lactate metabolic process | The chemical reactions and pathways involving lactate, the anion of lactic acid. |
PFKFB2, LDHA, LDHB, HIF1A |
GO:0006090 | BP | pyruvate metabolic process | The chemical reactions and pathways involving pyruvate, 2-oxopropanoate. |
SLC16A3, LDHA, LDHB, PDHA1, DLD, DLAT, PDHB, PC, BSG, GLO1, HAGH, ME3, PCK2 |
GO:0006091 | BP | generation of precursor metabolites and energy | The chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and any process involved in the liberation of energy from these substances. |
UQCR11, POMC, COX6C, COX6A1, SLC25A4, ADRB3, COX7C, ENPP1, DLST, PPP1R2, PHKA2, PHKA1, GNPDA1, GYS2, SLC25A3, OGDH, PPARD, GBE1, COX17, ACOX1, ADIPOQ, ACO2, CROT |
GO:0006094 | BP | gluconeogenesis | The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol. |
FBP2, SLC25A12, GOT2, PGK1, RBP4, ALDOA, GAPDH, ENO1, GPI, BPGM, ENO2, FBP1, ALDOC, PC, ENO3, PFKFB1, PGAM1, ATF3, ATF4, PCK1, G6PC, PGM1, MDH1, MDH2, GPD2, SLC25A1, TPI1, CRY1, PCK2, G6PC3, PPARGC1A, SLC25A10, SLC25A13 |
GO:0006096 | BP | glycolytic process | The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules. |
PFKFB2, LDHA, ALDOA, BPGM, PFKFB1, PFKL, PGAM1, HK1, PGM1, TPI1, OGDH, HKDC1 |
GO:0006097 | BP | glyoxylate cycle | A modification of the TCA cycle occurring in some plants and microorganisms, in which isocitrate is cleaved to glyoxylate and succinate. Glyoxylate can then react with acetyl-CoA to form malate. |
IDH1, IDH2 |
GO:0006098 | BP | pentose-phosphate shunt | The glucose-6-phosphate catabolic process in which, coupled to NADPH synthesis, glucose-6-P is oxidized with the formation of carbon dioxide (CO2) and ribulose 5-phosphate; ribulose 5-P then enters a series of reactions interconverting sugar phosphates. The pentose phosphate pathway is a major source of reducing equivalents for biosynthesis reactions and is also important for the conversion of hexoses to pentoses. |
PGLS, H6PD, G6PD, TKT, TALDO1, PGD, TPI1, PGM2, DERA |
GO:0006099 | BP | tricarboxylic acid cycle | A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate cycle. |
IDH3B, IDH1, FH, PDHA1, DLD, DLAT, PDHB, SDHB, SDHA, DLST, MDH1, MDH2, IDH2, SUCLG1, OGDH, MDH1B, SDHC, ACO2, SUCLA2 |
GO:0006101 | BP | citrate metabolic process | The chemical reactions and pathways involving citrate, 2-hydroxy-1,2,3-propanetricarboyxlate. Citrate is widely distributed in nature and is an important intermediate in the TCA cycle and the glyoxylate cycle. |
GHR, STAT5A, STAT5B, ACO2 |
GO:0006102 | BP | isocitrate metabolic process | The chemical reactions and pathways involving isocitrate, the anion of isocitric acid, 1-hydroxy-1,2,3-propanetricarboxylic acid. Isocitrate is an important intermediate in the TCA cycle and the glycoxylate cycle. |
IDH3B, IDH1, IDH2, ACO2 |
GO:0006103 | BP | 2-oxoglutarate metabolic process | The chemical reactions and pathways involving oxoglutarate, the dianion of 2-oxoglutaric acid. It is a key constituent of the TCA cycle and a key intermediate in amino-acid metabolism. |
IDH3B, IDH1, GOT2, DLD, GHR, STAT5A, IDH2, STAT5B, MRPS36, OGDH, ADHFE1, GPT2 |
GO:0006104 | BP | succinyl-CoA metabolic process | The chemical reactions and pathways involving succinyl-CoA, a compound composed of the monovalent acyl group 3-carboxypropanoyl, derived from succinic acid by loss of one OH group, linked to coenzyme A. |
SUCLG1, OGDH, ACOT4, SUCLA2 |
GO:0006105 | BP | succinate metabolic process | The chemical reactions and pathways involving succinate, also known as butanedioate or ethane dicarboxylate, the dianion of succinic acid. Succinate is an important intermediate in metabolism and a component of the TCA cycle. |
GHR, SDHB, SDHA, STAT5A, STAT5B, SUCLG1, SUCLA2 |
GO:0006106 | BP | fumarate metabolic process | The chemical reactions and pathways involving fumarate, the anion of trans-1,2-ethenedicarboxylic acid, the diastereoisomer of maleate. It is a key intermediate in metabolism and is formed in the TCA cycle from succinate and converted into malate. |
FH |
GO:0006107 | BP | oxaloacetate metabolic process | The chemical reactions and pathways involving oxaloacetate, the anion of oxobutanedioic acid, an important intermediate in metabolism, especially as a component of the TCA cycle. |
GOT2, GHR, PCK1, MDH1, MDH2, STAT5A, STAT5B, PCK2, MDH1B |
GO:0006108 | BP | malate metabolic process | The chemical reactions and pathways involving malate, the anion of hydroxybutanedioic acid, a chiral hydroxydicarboxylic acid. The (+) enantiomer is an important intermediate in metabolism as a component of both the TCA cycle and the glyoxylate cycle. |
FH, ME2, MDH1, MDH2, ME3, MDH1B |
GO:0006110 | BP | regulation of glycolytic process | Any process that modulates the frequency, rate or extent of glycolysis. |
OGT, PGAM1, PRKAG1, EIF6 |
GO:0006111 | BP | regulation of gluconeogenesis | Any process that modulates the frequency, rate or extent of gluconeogenesis, the formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol. |
FBP1, LEP, VIMP, NLN, SDHAF3 |
GO:0006112 | BP | energy reserve metabolic process | The chemical reactions and pathways by which a cell derives energy from stored compounds such as fats or glycogen. |
MYC, ADRB3, MT3, MC4R, LEP, LEPR, GNAS, GFPT1, GNAS, PID1, MRAP2, KL |
GO:0006114 | BP | glycerol biosynthetic process | The chemical reactions and pathways resulting in the formation of glycerol, 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids. |
LEP |
GO:0006116 | BP | NADH oxidation | A metabolic process that results in the oxidation of reduced nicotinamide adenine dinucleotide, NADH, to the oxidized form, NAD. |
PCK2 |
GO:0006117 | BP | acetaldehyde metabolic process | The chemical reactions and pathways involving acetaldehyde, a colorless, flammable liquid intermediate in the metabolism of alcohol. |
RELA |
GO:0006119 | BP | oxidative phosphorylation | The phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis. |
UQCRH, UQCRB, UQCRC2, ATP5D, UQCRC1, ATP5C1, MSH2, FXN, CHCHD10, TEFM |
GO:0006120 | BP | mitochondrial electron transport, NADH to ubiquinone | The transfer of electrons from NADH to ubiquinone that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex I. |
NDUFS8, NDUFA4, NDUFAB1, NDUFA1, NDUFS4, NDUFA2, NDUFS2, NDUFS6, NDUFB6, NDUFB4, NDUFB8, NDUFA7, NDUFA10, NDUFB10, DLD, NDUFB7, NDUFV2, NDUFS1, NDUFV3, NDUFA5, NDUFA11, NDUFB11, NDUFA13 |
GO:0006121 | BP | mitochondrial electron transport, succinate to ubiquinone | The transfer of electrons from succinate to ubiquinone that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex II. |
SDHC |
GO:0006122 | BP | mitochondrial electron transport, ubiquinol to cytochrome c | The transfer of electrons from ubiquinol to cytochrome c that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex III. |
UQCRHL, UQCRQ, UQCR11, PMPCB, UQCRH, CYC1, UQCRB, UQCRC2, UQCRC1, UQCRFS1, CYCS, UQCC3, UQCR10 |
GO:0006123 | BP | mitochondrial electron transport, cytochrome c to oxygen | The transfer of electrons from cytochrome c to oxygen that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex IV. |
NDUFA4, COX6C, COX5B, COX6A1, COX6B1, COX7C, COX5A, COX7B, CYCS |
GO:0006139 | BP | nucleobase-containing compound metabolic process | Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids. |
TK2, PNP, TK1, TYMS, PRPS2, CTPS1, DUT, TPMT, ERH, MTAP, DPYSL2, UPP1, SLC29A1, ZNRD1, SLC23A2, REXO2 |
GO:0006144 | BP | purine nucleobase metabolic process | The chemical reactions and pathways involving purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, which include adenine and guanine. |
ACPP, GMPR, PRPS1 |
GO:0006145 | BP | purine nucleobase catabolic process | The chemical reactions and pathways resulting in the breakdown of purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, which include adenine and guanine. |
DPYD |
GO:0006148 | BP | inosine catabolic process | The chemical reactions and pathways resulting in the breakdown of inosine, hypoxanthine riboside, a nucleoside found free but not in combination in nucleic acids except in the anticodons of some tRNAs. |
PNP |
GO:0006154 | BP | adenosine catabolic process | The chemical reactions and pathways resulting in the breakdown of adenosine, adenine riboside, a ribonucleoside found widely distributed in cells of every type as the free nucleoside and in combination in nucleic acids and various nucleoside coenzymes. |
ADA |
GO:0006157 | BP | deoxyadenosine catabolic process | The chemical reactions and pathways resulting in the breakdown of deoxyadenosine, 2-deoxyribosyladenine, one of the four major nucleosides of DNA. |
ADA |
GO:0006163 | BP | purine nucleotide metabolic process | The chemical reactions and pathways involving a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. |
NME4, NME1, NME2, FHIT, GUK1 |
GO:0006164 | BP | purine nucleotide biosynthetic process | The chemical reactions and pathways resulting in the formation of a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. |
PFAS, MTHFD1, ADSL, PRPS1, PPAT, MTHFD2L |
GO:0006165 | BP | nucleoside diphosphate phosphorylation | The process of introducing a phosphate group into a nucleoside diphosphate to produce a nucleoside triphosphate. |
NME4, NME6, AK1, NME1, NME2, AK4, CMPK1, PCK1, CMPK2, AK8, NME7 |
GO:0006166 | BP | purine ribonucleoside salvage | Any process which produces a purine nucleoside from derivatives of it, without de novo synthesis. |
MTAP |
GO:0006167 | BP | AMP biosynthetic process | The chemical reactions and pathways resulting in the formation of AMP, adenosine monophosphate. |
ADSS, ADSL, PRPS1, ADSSL1 |
GO:0006168 | BP | adenine salvage | Any process that generates adenine, 6-aminopurine, from derivatives of it without de novo synthesis. |
APRT |
GO:0006171 | BP | cAMP biosynthetic process | The chemical reactions and pathways resulting in the formation of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate). |
ADCY3, ADCY9, ADM, ADCY7 |
GO:0006172 | BP | ADP biosynthetic process | The chemical reactions and pathways resulting in the formation of ADP, adenosine 5'-diphosphate. |
AK1, AK4, AK3 |
GO:0006177 | BP | GMP biosynthetic process | The chemical reactions and pathways resulting in the formation of GMP, guanosine monophosphate. |
GMPS |
GO:0006182 | BP | cGMP biosynthetic process | The chemical reactions and pathways resulting in the formation of cyclic GMP, guanosine 3',5'-phosphate. |
NPPB, NPR2, HTR2C, HTR2B, GUCY2D |
GO:0006183 | BP | GTP biosynthetic process | The chemical reactions and pathways resulting in the formation of GTP, guanosine triphosphate. |
NME4, NME6, NME1, NME2, NME7 |
GO:0006185 | BP | dGDP biosynthetic process | The chemical reactions and pathways resulting in the formation of dGDP, deoxyguanosine diphosphate, (2'-deoxyguanosine 5'-diphosphate). |
GUK1 |
GO:0006189 | BP | de novo' IMP biosynthetic process | The chemical reactions and pathways resulting in the formation of IMP, inosine monophosphate, by the stepwise assembly of a purine ring on ribose 5-phosphate. |
PFAS, GART, PAICS, ADSL, PPAT |
GO:0006195 | BP | purine nucleotide catabolic process | The chemical reactions and pathways resulting in the breakdown of a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. |
PNP, GPX1, NT5E, NUDT1, XDH, NT5C, NUDT15 |
GO:0006196 | BP | AMP catabolic process | The chemical reactions and pathways resulting in the breakdown of AMP, adenosine monophosphate. |
NT5E, AMPD3 |
GO:0006198 | BP | cAMP catabolic process | The chemical reactions and pathways resulting in the breakdown of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate). |
PDE8A, PDE8B, PDE4C, PDE4D, PDE3B, PDE7A, PDE3A, PDE7B |
GO:0006203 | BP | dGTP catabolic process | The chemical reactions and pathways resulting in the breakdown of dGTP, guanosine triphosphate. |
NUDT1, NUDT15, SAMHD1 |
GO:0006206 | BP | pyrimidine nucleobase metabolic process | The chemical reactions and pathways involving pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases. |
TYMP, RRM1, UPRT, UCK2, UCK1, UCKL1 |
GO:0006207 | BP | de novo' pyrimidine nucleobase biosynthetic process | The chemical reactions and pathways resulting in the formation of pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases, beginning with the synthesis of a pyrimidine ring from simpler precursors. |
UMPS, CAD, CMPK1, DHODH |
GO:0006208 | BP | pyrimidine nucleobase catabolic process | The chemical reactions and pathways resulting in the breakdown of pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases. |
DPYD |
GO:0006210 | BP | thymine catabolic process | The chemical reactions and pathways resulting in the breakdown of thymine, 5-methyluracil, one of the two major pyrimidine bases present (as thymidine) in DNA but not found in RNA other than (as ribothymidine) in transfer RNA, where it is a minor base. |
ALDH6A1, DPYD |
GO:0006212 | BP | uracil catabolic process | The chemical reactions and pathways resulting in the breakdown of uracil, 2,4-dioxopyrimidine, one of the pyrimidine bases occurring in RNA, but not in DNA. |
DPYD |
GO:0006213 | BP | pyrimidine nucleoside metabolic process | The chemical reactions and pathways involving any pyrimidine nucleoside, one of a family of organic molecules consisting of a pyrimidine base covalently bonded to ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside). |
ERH |
GO:0006214 | BP | thymidine catabolic process | The chemical reactions and pathways resulting in the breakdown of thymidine, deoxyribosylthymine thymine 2-deoxyriboside, a deoxynucleoside very widely distributed but occurring almost entirely as phosphoric esters in deoxynucleotides and deoxyribonucleic acid, DNA. |
DPYD |
GO:0006218 | BP | uridine catabolic process | The chemical reactions and pathways resulting in the breakdown of uridine, uracil riboside, a ribonucleoside very widely distributed but occurring almost entirely as phosphoric esters in ribonucleotides and ribonucleic acids. |
UPP1 |
GO:0006220 | BP | pyrimidine nucleotide metabolic process | The chemical reactions and pathways involving a pyrimidine nucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. |
NME4, NME1, NME2, DCK, DCTD, CTPS2 |
GO:0006221 | BP | pyrimidine nucleotide biosynthetic process | The chemical reactions and pathways resulting in the formation of a pyrimidine nucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. |
PRPS1, ERH |
GO:0006222 | BP | UMP biosynthetic process | The chemical reactions and pathways resulting in the formation of UMP, uridine monophosphate. |
UMPS, CMPK1, UPRT |
GO:0006226 | BP | dUMP biosynthetic process | The chemical reactions and pathways resulting in the formation of dUMP, deoxyuridine monophosphate (2'-deoxyuridine 5'-phosphate). |
DUT |
GO:0006227 | BP | dUDP biosynthetic process | The chemical reactions and pathways resulting in the formation of dUDP, deoxyuridine diphosphate (2'-deoxy-5'-uridylyl phosphate). |
DTYMK, CMPK2 |
GO:0006228 | BP | UTP biosynthetic process | The chemical reactions and pathways resulting in the formation of UTP, uridine (5'-)triphosphate. |
NME4, NME6, NME1, NME2, CAD, NME7 |
GO:0006231 | BP | dTMP biosynthetic process | The chemical reactions and pathways resulting in the formation of dTMP, deoxyribosylthymine monophosphate (2'-deoxyribosylthymine 5'-phosphate). |
TYMS, SHMT1 |