| GO ID | Ontology | GO Term | Term Definition |
Proteins |
GO:2000753 | BP | positive regulation of glucosylceramide catabolic process | Any process that activates or increases the frequency, rate or extent of glucosylceramide catabolic process. |
PRKCD |
GO:2000755 | BP | positive regulation of sphingomyelin catabolic process | Any process that activates or increases the frequency, rate or extent of sphingomyelin catabolic process. |
PRKCD |
GO:2000757 | BP | negative regulation of peptidyl-lysine acetylation | Any process that stops, prevents or reduces the frequency, rate or extent of peptidyl-lysine acetylation. |
HDAC1, HDAC2, KLF15 |
GO:2000761 | BP | positive regulation of N-terminal peptidyl-lysine acetylation | Any process that activates or increases the frequency, rate or extent of N-terminal peptidyl-lysine acetylation. |
SOX4 |
GO:2000766 | BP | negative regulation of cytoplasmic translation | Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translation. |
FMR1, CPEB4, CPEB2, CPEB3, UNK |
GO:2000767 | BP | positive regulation of cytoplasmic translation | Any process that activates or increases the frequency, rate or extent of cytoplasmic translation. |
EEF2 |
GO:2000768 | BP | positive regulation of nephron tubule epithelial cell differentiation | Any process that activates or increases the frequency, rate or extent of nephron tubule epithelial cell differentiation. |
CD24 |
GO:2000772 | BP | regulation of cellular senescence | Any process that modulates the frequency, rate or extent of cellular senescence. |
ARNTL, NUAK1, RSL1D1, BMPR1A, NEK4, PNPT1, NEK6, ZNF277 |
GO:2000773 | BP | negative regulation of cellular senescence | Any process that stops, prevents or reduces the frequency, rate or extent of cellular senescence. |
BCL6, PRKDC, CDK6, TWIST1, BCL2L12 |
GO:2000774 | BP | positive regulation of cellular senescence | Any process that activates or increases the frequency, rate or extent of cellular senescence. |
EEF1E1, KRAS, HMGA1, HMGA2, YPEL3, PAWR |
GO:2000775 | BP | histone H3-S10 phosphorylation involved in chromosome condensation | Any histone H3-S10 phosphorylation that is involved in chromosome condensation. |
CCNB1 |
GO:2000777 | BP | positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia | Any positive regulation of proteasomal ubiquitin-dependent protein catabolic process that is involved in a cellular response to hypoxia. |
SIRT2 |
GO:2000778 | BP | positive regulation of interleukin-6 secretion | Any process that activates or increases the frequency, rate or extent of interleukin-6 secretion. |
IL1B, HMGB1, PAEP, HSPD1, XBP1, F2R, F2RL1, HYAL2, TWIST1, TRPV4, IL1RAP, PYCARD |
GO:2000779 | BP | regulation of double-strand break repair | Any process that modulates the frequency, rate or extent of double-strand break repair. |
DEK |
GO:2000780 | BP | negative regulation of double-strand break repair | Any process that stops, prevents or reduces the frequency, rate or extent of double-strand break repair. |
UBR5, TWIST1, RNF169, OTUB1 |
GO:2000781 | BP | positive regulation of double-strand break repair | Any process that activates or increases the frequency, rate or extent of double-strand break repair. |
FOXM1, SPIDR, SLF2, NUDT16, SLF1 |
GO:2000785 | BP | regulation of autophagosome assembly | Any process that modulates the frequency, rate or extent of autophagosome assembly. |
TBC1D12, RAB5A, RAB7A, NPRL3, RAB33A, RAB1B, TBC1D14, PIKFYVE |
GO:2000786 | BP | positive regulation of autophagosome assembly | Any process that activates or increases the frequency, rate or extent of autophagic vacuole assembly. |
RALB, PIP4K2B, RAB3GAP1, KIAA1324, RAB3GAP2, SH3GLB1 |
GO:2000791 | BP | negative regulation of mesenchymal cell proliferation involved in lung development | Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell proliferation involved in lung development. |
NFIB |
GO:2000793 | BP | cell proliferation involved in heart valve development | Any cell proliferation that is involved in heart valve development. |
TWIST1 |
GO:2000794 | BP | regulation of epithelial cell proliferation involved in lung morphogenesis | Any process that modulates the frequency, rate or extent of epithelial cell proliferation involved in lung morphogenesis. |
SOX9 |
GO:2000795 | BP | negative regulation of epithelial cell proliferation involved in lung morphogenesis | Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell proliferation involved in lung morphogenesis. |
NFIB |
GO:2000802 | BP | positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation | Any process that activates or increases the frequency, rate or extent of endocardial cushion to mesenchymal transition involved in heart valve formation. |
TWIST1 |
GO:2000806 | BP | positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled | Any process that activates or increases the frequency, rate or extent of termination of RNA polymerase II transcription, poly(A)-coupled. |
SETX |
GO:2000807 | BP | regulation of synaptic vesicle clustering | Any process that modulates the frequency, rate or extent of synaptic vesicle clustering. |
PCDH17 |
GO:2000808 | BP | negative regulation of synaptic vesicle clustering | Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle clustering. |
PTEN |
GO:2000809 | BP | positive regulation of synaptic vesicle clustering | Any process that activates or increases the frequency, rate or extent of synaptic vesicle clustering. |
CDH2, MAGI2, NLGN1 |
GO:2000810 | BP | regulation of bicellular tight junction assembly | Any process that modulates the frequency, rate or extent of tight junction assembly. |
MYO1C, SNAI2, GJA1, PRKACA, PKP2 |
GO:2000811 | BP | negative regulation of anoikis | Any process that stops, prevents or reduces the frequency, rate or extent of anoikis. |
SNAI2, ITGB1, ITGA5, BCL2, PIK3CA, NOTCH1, CAV1, TLE1, PTK2, MCL1, NTRK2, PDK4 |
GO:2000812 | BP | regulation of barbed-end actin filament capping | Any process that modulates the frequency, rate or extent of barbed-end actin filament capping. |
MTPN |
GO:2000813 | BP | negative regulation of barbed-end actin filament capping | Any process that stops, prevents or reduces the frequency, rate or extent of barbed-end actin filament capping. |
LRRC16A |
GO:2000818 | BP | negative regulation of myoblast proliferation | Any process that stops, prevents or reduces the frequency, rate or extent of myoblast proliferation. |
MSTN |
GO:2000819 | BP | regulation of nucleotide-excision repair | Any process that modulates the frequency, rate or extent of nucleotide-excision repair. |
CUL4A |
GO:2000820 | BP | negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation | Any negative regulation of transcription from RNA polymerase II promoter that is involved in smooth muscle cell differentiation. |
HEY1 |
GO:2000821 | BP | regulation of grooming behavior | Any process that modulates the frequency, rate or extent of grooming behavior. |
MC4R, DLG4, NRXN1 |
GO:2000824 | BP | negative regulation of androgen receptor activity | Any process that stops, prevents or reduces the frequency, rate or extent of androgen receptor activity. |
HEYL |
GO:2000825 | BP | positive regulation of androgen receptor activity | Any process that activates or increases the frequency, rate or extent of androgen receptor activity. |
BUD31 |
GO:2000827 | BP | mitochondrial RNA surveillance | The set of processes involved in identifying and degrading defective or aberrant RNAs that takes place in the mitochondrion. |
SUPV3L1 |
GO:2000828 | BP | regulation of parathyroid hormone secretion | Any process that modulates the frequency, rate or extent of parathyroid hormone secretion. |
GNAS, GNAS |
GO:2000830 | BP | positive regulation of parathyroid hormone secretion | Any process that activates or increases the frequency, rate or extent of parathyroid hormone secretion. |
FGFR1 |
GO:2000845 | BP | positive regulation of testosterone secretion | Any process that activates or increases the frequency, rate or extent of testosterone secretion. |
TMF1 |
GO:2000850 | BP | negative regulation of glucocorticoid secretion | Any process that stops, prevents or reduces the frequency, rate or extent of glucocorticoid secretion. |
CRY1 |
GO:2000852 | BP | regulation of corticosterone secretion | Any process that modulates the frequency, rate or extent of corticosterone secretion. |
POMC |
GO:2000860 | BP | positive regulation of aldosterone secretion | Any process that activates or increases the frequency, rate or extent of aldosterone secretion. |
BMP6, C1QTNF1 |
GO:2000864 | BP | regulation of estradiol secretion | Any process that modulates the frequency, rate or extent of estradiol secretion. |
KDM5B |
GO:2000870 | BP | regulation of progesterone secretion | Any process that modulates the frequency, rate or extent of progesterone secretion. |
GDF9 |
GO:2000872 | BP | positive regulation of progesterone secretion | Any process that activates or increases the frequency, rate or extent of progesterone secretion. |
RETN |
GO:2000969 | BP | positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity | Any process that activates or increases the frequency, rate or extent of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity. |
ARC |
GO:2000973 | BP | regulation of pro-B cell differentiation | Any process that modulates the frequency, rate or extent of pro-B cell differentiation. |
SOS1, FLCN, FNIP1 |
GO:2000974 | BP | negative regulation of pro-B cell differentiation | Any process that stops, prevents or reduces the frequency, rate or extent of pro-B cell differentiation. |
NOTCH1, HES1 |
GO:2000978 | BP | negative regulation of forebrain neuron differentiation | Any process that stops, prevents or reduces the frequency, rate or extent of forebrain neuron differentiation. |
HES1 |
GO:2000979 | BP | positive regulation of forebrain neuron differentiation | Any process that activates or increases the frequency, rate or extent of forebrain neuron differentiation. |
PROX1 |
GO:2000984 | BP | negative regulation of ATP citrate synthase activity | Any process that stops, prevents or reduces the frequency, rate or extent of ATP citrate synthase activity. |
CHCHD10, PHPT1 |
GO:2000987 | BP | positive regulation of behavioral fear response | Any process that activates or increases the frequency, rate or extent of behavioral fear response. |
PENK, GJA1, MEF2C |
GO:2001013 | BP | epithelial cell proliferation involved in renal tubule morphogenesis | Any epithelial cell proliferation that is involved in renal tubule morphogenesis. |
MTSS1, LGR5, MEF2C, LGR4 |
GO:2001014 | BP | regulation of skeletal muscle cell differentiation | Any process that modulates the frequency, rate or extent of skeletal muscle cell differentiation. |
DDX5, NR1D2, DDX17, UQCC2 |
GO:2001015 | BP | negative regulation of skeletal muscle cell differentiation | Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle cell differentiation. |
S100B, CAPN3 |
GO:2001016 | BP | positive regulation of skeletal muscle cell differentiation | Any process that activates or increases the frequency, rate or extent of skeletal muscle cell differentiation. |
ARNTL, GPC1, MEF2C |
GO:2001020 | BP | regulation of response to DNA damage stimulus | Any process that modulates the frequency, rate or extent of response to DNA damage stimulus. |
IER3, NEK4, CASP9, MCL1, NPAS2 |
GO:2001022 | BP | positive regulation of response to DNA damage stimulus | Any process that activates or increases the frequency, rate or extent of response to DNA damage stimulus. |
MYC, HMGA2, PRKCD, FMR1, NSMCE4A, BCLAF1 |
GO:2001023 | BP | regulation of response to drug | Any process that modulates the frequency, rate or extent of response to drug. |
ADIRF |
GO:2001027 | BP | negative regulation of endothelial cell chemotaxis | Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell chemotaxis. |
THBS1, NOTCH1 |
GO:2001028 | BP | positive regulation of endothelial cell chemotaxis | Any process that activates or increases the frequency, rate or extent of endothelial cell chemotaxis. |
HSPB1, MET, SEMA5A, PRKD1, PRKD2 |
GO:2001032 | BP | regulation of double-strand break repair via nonhomologous end joining | Any process that modulates the frequency, rate or extent of double-strand break repair via nonhomologous end joining. |
WHSC1, DEK |
GO:2001033 | BP | negative regulation of double-strand break repair via nonhomologous end joining | Any process that stops, prevents or reduces the frequency, rate or extent of double-strand break repair via nonhomologous end joining. |
HMGA2 |
GO:2001034 | BP | positive regulation of double-strand break repair via nonhomologous end joining | Any process that activates or increases the frequency, rate or extent of double-strand break repair via nonhomologous end joining. |
RIF1 |
GO:2001037 | BP | positive regulation of tongue muscle cell differentiation | Any process that activates or increases the frequency, rate or extent of tongue muscle cell differentiation. |
TBX1, CYP26B1 |
GO:2001038 | BP | regulation of cellular response to drug | Any process that modulates the frequency, rate or extent of cellular response to drug. |
HMGA2, NCOA1 |
GO:2001044 | BP | regulation of integrin-mediated signaling pathway | Any process that modulates the frequency, rate or extent of integrin-mediated signaling pathway. |
ITGB1BP1, TIMP1, PRKD1 |
GO:2001045 | BP | negative regulation of integrin-mediated signaling pathway | Any process that stops, prevents or reduces the frequency, rate or extent of integrin-mediated signaling pathway. |
CTNNA1, PHACTR4 |
GO:2001046 | BP | positive regulation of integrin-mediated signaling pathway | Any process that activates or increases the frequency, rate or extent of integrin-mediated signaling pathway. |
FLNA, EMP2 |
GO:2001054 | BP | negative regulation of mesenchymal cell apoptotic process | Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell apoptotic process. |
TBX1, GDF5, SOX9, HIF1A |
GO:2001056 | BP | positive regulation of cysteine-type endopeptidase activity | Any process that activates or increases the frequency, rate or extent of cysteine-type endopeptidase activity. |
PYCARD |
GO:2001065 | MF | mannan binding | Interacting selectively and non-covalently with mannan. |
FCN2 |
GO:2001069 | MF | glycogen binding | Interacting selectively and non-covalently with glycogen. |
PPP1R3F |
GO:2001076 | BP | positive regulation of metanephric ureteric bud development | Any process that activates or increases the frequency, rate or extent of metanephric ureteric bud development. |
WT1 |
GO:2001106 | BP | regulation of Rho guanyl-nucleotide exchange factor activity | Any process that modulates the frequency, rate or extent of Rho guanyl-nucleotide exchange factor activity. |
CCPG1 |
GO:2001108 | BP | positive regulation of Rho guanyl-nucleotide exchange factor activity | Any process that activates or increases the frequency, rate or extent of Rho guanyl-nucleotide exchange factor activity. |
EPHA4 |
GO:2001113 | BP | negative regulation of cellular response to hepatocyte growth factor stimulus | Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to hepatocyte growth factor stimulus. |
ADAMTS12 |
GO:2001135 | BP | regulation of endocytic recycling | Any process that modulates the frequency, rate or extent of endocytic recycling. |
RAB11B, BVES, NDRG4 |
GO:2001137 | BP | positive regulation of endocytic recycling | Any process that activates or increases the frequency, rate or extent of endocytic recycling. |
ACTN2, SORL1 |
GO:2001140 | BP | positive regulation of phospholipid transport | Any process that activates or increases the frequency, rate or extent of phospholipid transport. |
TRIAP1, PRELID1 |
GO:2001141 | BP | regulation of RNA biosynthetic process | Any process that modulates the frequency, rate or extent of RNA biosynthetic process. |
MITF, NCOA3 |
GO:2001150 | BP | positive regulation of dipeptide transmembrane transport | Any process that activates or increases the frequency, rate or extent of dipeptide transmembrane transport. |
CA2 |
GO:2001153 | BP | positive regulation of renal water transport | Any process that activates or increases the frequency, rate or extent of renal water transport. |
INPP5K |
GO:2001170 | BP | negative regulation of ATP biosynthetic process | Any process that stops, prevents or reduces the frequency, rate or extent of ATP biosynthetic process. |
PID1, FLCN |
GO:2001171 | BP | positive regulation of ATP biosynthetic process | Any process that activates or increases the frequency, rate or extent of ATP biosynthetic process. |
STAT3, VCP, PID1, PINK1, PPARGC1A |
GO:2001180 | BP | negative regulation of interleukin-10 secretion | Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-10 secretion. |
TNFRSF21, LILRB1 |
GO:2001181 | BP | positive regulation of interleukin-10 secretion | Any process that activates or increases the frequency, rate or extent of interleukin-10 secretion. |
PYCARD |
GO:2001182 | BP | regulation of interleukin-12 secretion | Any process that modulates the frequency, rate or extent of interleukin-12 secretion. |
FOXP1 |
GO:2001183 | BP | negative regulation of interleukin-12 secretion | Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-12 secretion. |
LILRB1 |
GO:2001184 | BP | positive regulation of interleukin-12 secretion | Any process that activates or increases the frequency, rate or extent of interleukin-12 secretion. |
MAPK14 |
GO:2001186 | BP | negative regulation of CD8-positive, alpha-beta T cell activation | Any process that stops, prevents or reduces the frequency, rate or extent of CD8-positive, alpha-beta T cell activation. |
HFE, LILRB1 |
GO:2001189 | BP | negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell | Any process that stops, prevents or reduces the frequency, rate or extent of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell. |
LGALS3, LILRB1 |
GO:2001190 | BP | positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell | Any process that activates or increases the frequency, rate or extent of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell. |
HLA-DMB |
GO:2001193 | BP | positive regulation of gamma-delta T cell activation involved in immune response | Any process that activates or increases the frequency, rate or extent of gamma-delta T cell activation involved in immune response. |
LILRB1 |
GO:2001199 | BP | negative regulation of dendritic cell differentiation | Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell differentiation. |
HLA-G, TMEM176B, LILRB1, TMEM176A |
GO:2001200 | BP | positive regulation of dendritic cell differentiation | Any process that activates or increases the frequency, rate or extent of dendritic cell differentiation. |
HMGB1 |
GO:2001202 | BP | negative regulation of transforming growth factor-beta secretion | Any process that stops, prevents or reduces the frequency, rate or extent of transforming growth factor-beta secretion. |
FN1, LILRB1 |
GO:2001204 | BP | regulation of osteoclast development | Any process that modulates the frequency, rate or extent of osteoclast development. |
TYROBP |