| GO ID | Ontology | GO Term | Term Definition |
Proteins |
GO:2000158 | BP | positive regulation of ubiquitin-specific protease activity | Any process that activates or increases the frequency, rate or extent of ubiquitin-specific protease (deubiquitinase) activity. |
VCP, TANK |
GO:2000167 | BP | regulation of planar cell polarity pathway involved in neural tube closure | Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in neural tube closure. |
NPHP3 |
GO:2000170 | BP | positive regulation of peptidyl-cysteine S-nitrosylation | Any process that activates or increases the frequency, rate or extent of peptidyl-cysteine S-nitrosylation. |
ACE |
GO:2000171 | BP | negative regulation of dendrite development | Any process that stops, prevents, or reduces the frequency, rate or extent of dendrite development. |
CARM1 |
GO:2000172 | BP | regulation of branching morphogenesis of a nerve | Any process that modulates the frequency, rate or extent of branching morphogenesis of a nerve. |
SHOX2, RTN4 |
GO:2000177 | BP | regulation of neural precursor cell proliferation | Any process that modulates the frequency, rate or extent of neural precursor cell proliferation. |
FOXO3, NF2, FOXO1, SHCBP1, PTBP2 |
GO:2000178 | BP | negative regulation of neural precursor cell proliferation | Any process that stops, prevents, or reduces the frequency, rate or extent of neural precursor cell proliferation. |
SPINT2, BTG2, ID2, ILK, RAPGEF1 |
GO:2000179 | BP | positive regulation of neural precursor cell proliferation | Any process that activates or increases the frequency, rate or extent of neural precursor cell proliferation. |
KDM1A, NES, ASCL1, GNG5, INSM1, KIAA1524, PROX1, DLL4, ADGRG1 |
GO:2000182 | BP | regulation of progesterone biosynthetic process | Any process that modulates the frequency, rate or extent of progesterone biosynthetic process. |
EGR1 |
GO:2000184 | BP | positive regulation of progesterone biosynthetic process | Any process that activates or increases the frequency, rate or extent of progesterone biosynthetic process. |
PPARGC1A |
GO:2000188 | BP | regulation of cholesterol homeostasis | Any process that modulates the frequency, rate or extent of cholesterol homeostasis. |
LDLR, NR1D1, RORA, NR1H2, SREBF2, NR1H3, NR1H4 |
GO:2000189 | BP | positive regulation of cholesterol homeostasis | Any process that activates or increases the frequency, rate or extent of cholesterol homeostasis. |
NPC1, NR1H3 |
GO:2000191 | BP | regulation of fatty acid transport | Any process that modulates the frequency, rate or extent of fatty acid transport. |
NCOR1, REPIN1 |
GO:2000194 | BP | regulation of female gonad development | Any process that modulates the frequency, rate or extent of female gonad development. |
NUPR1, INSR |
GO:2000195 | BP | negative regulation of female gonad development | Any process that stops, prevents, or reduces the frequency, rate or extent of female gonad development. |
WT1, ZFPM2 |
GO:2000210 | BP | positive regulation of anoikis | Any process that activates or increases the frequency, rate or extent of anoikis. |
SIK1, AES, MYBBP1A |
GO:2000213 | BP | positive regulation of glutamate metabolic process | Any process that activates or increases the frequency, rate or extent of glutamate metabolic process. |
NR1H4 |
GO:2000224 | BP | regulation of testosterone biosynthetic process | Any process that modulates the frequency, rate or extent of testosterone biosynthetic process. |
AKR1C3 |
GO:2000227 | BP | negative regulation of pancreatic A cell differentiation | Any process that stops, prevents, or reduces the frequency, rate or extent of pancreatic A cell differentiation. |
HES1 |
GO:2000230 | BP | negative regulation of pancreatic stellate cell proliferation | Any process that stops, prevents, or reduces the frequency, rate or extent of pancreatic stellate cell proliferation. |
PPARG |
GO:2000233 | BP | negative regulation of rRNA processing | Any process that stops, prevents, or reduces the frequency, rate or extent of rRNA processing. |
SHQ1, NUDT16 |
GO:2000249 | BP | regulation of actin cytoskeleton reorganization | Any process that modulates the frequency, rate or extent of actin cytoskeleton reorganization. |
RHOD, SEMA3E, DAPK3, TGFB1, CSF1R, PDGFRA, ABL2, ARHGDIA, ARHGDIB, PHPT1, F11R |
GO:2000251 | BP | positive regulation of actin cytoskeleton reorganization | Any process that activates or increases the frequency, rate or extent of actin cytoskeleton reorganization. |
HAX1, HCLS1, CDK5, TEK, BAIAP2L1 |
GO:2000252 | BP | negative regulation of feeding behavior | Any process that stops, prevents or reduces the frequency, rate or extent of feeding behavior. |
INS, TRH, MC4R, NPY2R, RETN |
GO:2000253 | BP | positive regulation of feeding behavior | Any process that activates or increases the frequency, rate or extent of feeding behavior. |
AGRP, NR4A3 |
GO:2000255 | BP | negative regulation of male germ cell proliferation | Any process that stops, prevents or reduces the frequency, rate or extent of male germ cell proliferation. |
PTGDS, PRDX4 |
GO:2000256 | BP | positive regulation of male germ cell proliferation | Any process that activates or increases the frequency, rate or extent of male germ cell proliferation. |
CIB1 |
GO:2000266 | BP | regulation of blood coagulation, intrinsic pathway | Any process that modulates the frequency, rate or extent of blood coagulation, intrinsic pathway. |
SERPINC1 |
GO:2000269 | BP | regulation of fibroblast apoptotic process | Any process that modulates the frequency, rate or extent of fibroblast apoptotic process. |
IER3IP1 |
GO:2000270 | BP | negative regulation of fibroblast apoptotic process | Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast apoptotic process. |
PIK3CA, PIK3CG, GAS6, SFRP1, CHD8, CFDP1 |
GO:2000271 | BP | positive regulation of fibroblast apoptotic process | Any process that activates or increases the frequency, rate or extent of fibroblast apoptotic process. |
BCL2L11, STK17B, BTG1, SFRP1 |
GO:2000272 | BP | negative regulation of receptor activity | Any process that stops, prevents or reduces the frequency, rate or extent of receptor activity. |
HFE, LYPD1, PCSK9, PPARGC1A |
GO:2000273 | BP | positive regulation of receptor activity | Any process that activates or increases the frequency, rate or extent of receptor activity. |
GREM1, IGF2, ANXA2, ACTN2, CDK5, NCOA2, HFE, PPARGC1B, SRA1, BAZ1B, MED16 |
GO:2000276 | BP | negative regulation of oxidative phosphorylation uncoupler activity | Any process that stops, prevents or reduces the frequency, rate or extent of oxidative phosphorylation uncoupler activity. |
PPIF, TWIST1 |
GO:2000278 | BP | regulation of DNA biosynthetic process | Any process that modulates the frequency, rate or extent of DNA biosynthetic process. |
CDKN1A, SH2B1 |
GO:2000279 | BP | negative regulation of DNA biosynthetic process | Any process that stops, prevents or reduces the frequency, rate or extent of DNA biosynthetic process. |
GJA1, DUSP1, BMPR2, ANKRD1, RGN, ADIPOQ, DACH1 |
GO:2000286 | BP | receptor internalization involved in canonical Wnt signaling pathway | A receptor internalization process that contributes to canonical Wnt signaling pathway. |
RAB5A, CAV1 |
GO:2000288 | BP | positive regulation of myoblast proliferation | Any process that activates or increases the frequency, rate or extent of myoblast proliferation. |
SOX15, PPARD, PITX2, PAXBP1 |
GO:2000296 | BP | negative regulation of hydrogen peroxide catabolic process | Any process that stops, prevents or reduces the frequency, rate or extent of hydrogen peroxide catabolic process. |
HP, MT3 |
GO:2000297 | BP | negative regulation of synapse maturation | Any process that stops, prevents or reduces the frequency, rate or extent of synapse maturation. |
NFATC4 |
GO:2000299 | BP | negative regulation of Rho-dependent protein serine/threonine kinase activity | Any process that stops, prevents or reduces the frequency, rate or extent of Rho-dependent protein serine/threonine kinase activity. |
CHORDC1 |
GO:2000300 | BP | regulation of synaptic vesicle exocytosis | Any process that modulates the frequency, rate or extent of synaptic vesicle exocytosis. |
SYN1, RAB5A, RIMS4, RIMS2 |
GO:2000301 | BP | negative regulation of synaptic vesicle exocytosis | Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle exocytosis. |
RAP1A, FMR1 |
GO:2000302 | BP | positive regulation of synaptic vesicle exocytosis | Any process that activates or increases the frequency, rate or extent of synaptic vesicle exocytosis. |
NLGN1 |
GO:2000304 | BP | positive regulation of ceramide biosynthetic process | Any process that activates or increases the frequency, rate or extent of ceramide biosynthetic process. |
CYR61, TNF, RACK1, PRKCD, NSMAF |
GO:2000309 | BP | positive regulation of tumor necrosis factor (ligand) superfamily member 11 production | Any process that activates or increases the frequency, rate or extent of tumor necrosis factor (ligand) superfamily member 11 production. |
ADAM8 |
GO:2000310 | BP | regulation of N-methyl-D-aspartate selective glutamate receptor activity | Any process that modulates the frequency, rate or extent of N-methyl-D-aspartate selective glutamate receptor activity. |
DAPK1, DLG4, MEF2C, MAPK8IP2, NLGN1, PPARGC1A |
GO:2000311 | BP | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity | Any process that modulates the frequency, rate or extent of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity. |
MEF2C, MAPK8IP2, NLGN1, MINK1, CACNG8 |
GO:2000312 | BP | regulation of kainate selective glutamate receptor activity | Any process that modulates the frequency, rate or extent of kainate selective glutamate receptor activity. |
KLHL24, NETO2 |
GO:2000318 | BP | positive regulation of T-helper 17 type immune response | Any process that activates or increases the frequency, rate or extent of T-helper 17 type immune response. |
IL12RB1, PRKCQ |
GO:2000320 | BP | negative regulation of T-helper 17 cell differentiation | Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 17 cell differentiation. |
FOXP3 |
GO:2000323 | BP | negative regulation of glucocorticoid receptor signaling pathway | Any process that stops, prevents or reduces the frequency, rate or extent of glucocorticoid receptor signaling pathway. |
ARNTL, PER1, PHB, CRY1 |
GO:2000327 | BP | positive regulation of ligand-dependent nuclear receptor transcription coactivator activity | Any process that activates or increases the frequency, rate or extent of ligand-dependent nuclear receptor transcription coactivator activity. |
CNOT6 |
GO:2000330 | BP | positive regulation of T-helper 17 cell lineage commitment | Any process that activates or increases the frequency, rate or extent of T-helper 17 cell lineage commitment. |
IL12RB1 |
GO:2000334 | BP | positive regulation of blood microparticle formation | Any process that activates or increases the frequency, rate or extent of blood microparticle formation. |
TNF, CD36 |
GO:2000340 | BP | positive regulation of chemokine (C-X-C motif) ligand 1 production | Any process that activates or increases the frequency, rate or extent of chemokine (C-X-C motif) ligand 1 production. |
TIRAP, TRPV4 |
GO:2000342 | BP | negative regulation of chemokine (C-X-C motif) ligand 2 production | Any process that stops, prevents or reduces the frequency, rate or extent of chemokine (C-X-C motif) ligand 2 production. |
KLF4, MAP2K5 |
GO:2000343 | BP | positive regulation of chemokine (C-X-C motif) ligand 2 production | Any process that activates or increases the frequency, rate or extent of chemokine (C-X-C motif) ligand 2 production. |
TNF, CD74, MIF, TIRAP, HDAC1 |
GO:2000344 | BP | positive regulation of acrosome reaction | Any process that activates or increases the frequency, rate or extent of the acrosome reaction. |
ZP3, PLCB1 |
GO:2000345 | BP | regulation of hepatocyte proliferation | Any process that modulates the frequency, rate or extent of hepatocyte proliferation. |
SULF2 |
GO:2000346 | BP | negative regulation of hepatocyte proliferation | Any process that stops, prevents or reduces the frequency, rate or extent of hepatocyte proliferation. |
CPB2 |
GO:2000347 | BP | positive regulation of hepatocyte proliferation | Any process that activates or increases the frequency, rate or extent of hepatocyte proliferation. |
XBP1, TNFAIP3 |
GO:2000348 | BP | regulation of CD40 signaling pathway | Any process that modulates the frequency, rate or extent of signaling via the CD40 signaling pathway. |
FANCD2 |
GO:2000349 | BP | negative regulation of CD40 signaling pathway | Any process that stops, prevents or reduces the frequency, rate or extent of signaling via the CD40 signaling pathway. |
TNFAIP3 |
GO:2000351 | BP | regulation of endothelial cell apoptotic process | Any process that modulates the frequency, rate or extent of endothelial cell apoptotic process. |
TEK |
GO:2000352 | BP | negative regulation of endothelial cell apoptotic process | Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell apoptotic process. |
KRIT1, FGA, FGB, FGG, SERPINE1, ICAM1, SCG2, TNFAIP3, TEK, MAPK7, SEMA5A, GAS6, ANGPT1, NDNF |
GO:2000353 | BP | positive regulation of endothelial cell apoptotic process | Any process that activates or increases the frequency, rate or extent of endothelial cell apoptotic process. |
FOXO3, THBS1, CD40LG, COL18A1, PRKCI, AKR1C3, ANO6, GPER1, RGCC, CD248 |
GO:2000354 | BP | regulation of ovarian follicle development | Any process that modulates the frequency, rate or extent of ovarian follicle development. |
GNRH1 |
GO:2000355 | BP | negative regulation of ovarian follicle development | Any process that stops, prevents or reduces the frequency, rate or extent of ovarian follicle development. |
AMH |
GO:2000360 | BP | negative regulation of binding of sperm to zona pellucida | Any process that stops, prevents or reduces the frequency, rate or extent of binding of sperm to the zona pellucida. |
ZP3 |
GO:2000366 | BP | positive regulation of STAT protein import into nucleus | Any process that activates or increases the frequency, rate or extent of STAT protein import into nucleus. |
IL6, LEP, ERBB4 |
GO:2000368 | BP | positive regulation of acrosomal vesicle exocytosis | Any process that activates or increases the frequency, rate or extent of acrosomal vesicle exocytosis. |
ZP3 |
GO:2000369 | BP | regulation of clathrin-dependent endocytosis | Any process that modulates the frequency, rate or extent of clathrin-mediated endocytosis. |
PIK3CB, TNK2, AAK1 |
GO:2000370 | BP | positive regulation of clathrin-dependent endocytosis | Any process that activates or increases the frequency, rate or extent of clathrin-mediated endocytosis. |
WASL, DAB2 |
GO:2000373 | BP | positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity | Any process that activates or increases the frequency, rate or extent of DNA topoisomerase (ATP-hydrolyzing) activity. |
PLSCR1, HNRNPU, UHRF1 |
GO:2000376 | BP | positive regulation of oxygen metabolic process | Any process that activates or increases the frequency, rate or extent of oxygen metabolic process. |
MT3 |
GO:2000377 | BP | regulation of reactive oxygen species metabolic process | Any process that modulates the frequency, rate or extent of reactive oxygen species metabolic process. |
PARK2, TUSC2, ARF4, MPV17, EIF6, FOXM1, FOXO1, CYP1B1, PID1, PINK1 |
GO:2000378 | BP | negative regulation of reactive oxygen species metabolic process | Any process that stops, prevents or reduces the frequency, rate or extent of reactive oxygen species metabolic process. |
PARK2, CRYAB, MYCN, BCL2, G6PD, MT3, BRCA1, PLIN5, BNIP3, HIF1A, SIRT2, PINK1, AATF |
GO:2000379 | BP | positive regulation of reactive oxygen species metabolic process | Any process that activates or increases the frequency, rate or extent of reactive oxygen species metabolic process. |
F2, AGT, PDGFB, TP53, THBS1, PDGFRB, NQO2, CD36, GADD45A, TSPO, AGTR1, TGFBR2, CDKN1A, LEP, AKR1C3, XDH, ROMO1, GRB2, RIPK1, MAPK14, DUOXA1, PID1, NOX4 |
GO:2000386 | BP | positive regulation of ovarian follicle development | Any process that activates or increases the frequency, rate or extent of ovarian follicle development. |
ZP3 |
GO:2000388 | BP | positive regulation of antral ovarian follicle growth | Any process that activates or increases the frequency, rate or extent of antral ovarian follicle growth. |
ZP3 |
GO:2000391 | BP | positive regulation of neutrophil extravasation | Any process that activates or increases the frequency, rate or extent of neutrophil extravasation. |
IL1A, IL1R1, ADAM8 |
GO:2000393 | BP | negative regulation of lamellipodium morphogenesis | Any process that stops, prevents or reduces the frequency, rate or extent of lamellipodium morphogenesis. |
KANK1, ARPIN |
GO:2000394 | BP | positive regulation of lamellipodium morphogenesis | Any process that activates or increases the frequency, rate or extent of lamellipodium morphogenesis. |
ENPP2, ARHGEF7, CORO1B, CORO1C |
GO:2000402 | BP | negative regulation of lymphocyte migration | Any process that stops, prevents or reduces the frequency, rate or extent of lymphocyte migration. |
WASL |
GO:2000405 | BP | negative regulation of T cell migration | Any process that stops, prevents or reduces the frequency, rate or extent of T cell migration. |
APOD |
GO:2000406 | BP | positive regulation of T cell migration | Any process that activates or increases the frequency, rate or extent of T cell migration. |
CCL5, CXCL12, CCL20, PYCARD |
GO:2000415 | BP | positive regulation of fibronectin-dependent thymocyte migration | Any process that activates or increases the frequency, rate or extent of fibronectin-dependent thymocyte migration. |
ADAM8 |
GO:2000418 | BP | positive regulation of eosinophil migration | Any process that activates or increases the frequency, rate or extent of eosinophil migration. |
ADAM8 |
GO:2000420 | BP | negative regulation of eosinophil extravasation | Any process that stops, prevents or reduces the frequency, rate or extent of eosinophil extravasation. |
PTGER4 |
GO:2000425 | BP | regulation of apoptotic cell clearance | Any process that modulates the frequency, rate or extent of apoptotic cell clearance. |
ITGAV |
GO:2000427 | BP | positive regulation of apoptotic cell clearance | Any process that activates or increases the frequency, rate or extent of apoptotic cell clearance. |
C3, C4A, C4B, CCL2, MFGE8 |
GO:2000438 | BP | negative regulation of monocyte extravasation | Any process that stops, prevents or reduces the frequency, rate or extent of monocyte extravasation. |
PLCB1 |
GO:2000439 | BP | positive regulation of monocyte extravasation | Any process that activates or increases the frequency, rate or extent of monocyte extravasation. |
PDGFD |
GO:2000446 | BP | regulation of macrophage migration inhibitory factor signaling pathway | Any process that modulates the frequency, rate or extent of macrophage migration inhibitory factor signaling pathway. |
ANGPT1 |
GO:2000454 | BP | positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation | Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta cytotoxic T cell extravasation. |
FADD |
GO:2000458 | BP | regulation of astrocyte chemotaxis | Any process that modulates the frequency, rate or extent of astrocyte chemotaxis. |
GPR183 |
GO:2000463 | BP | positive regulation of excitatory postsynaptic potential | Any process that enhances the establishment or increases the extent of the excitatory postsynaptic potential (EPSP) which is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential. |
PTEN, DLG4, NLGN1, NRXN1, RIMS2 |
GO:2000465 | BP | regulation of glycogen (starch) synthase activity | Any process that modulates the frequency, rate or extent of glycogen (starch) synthase activity. |
PPP1R3F |
GO:2000466 | BP | negative regulation of glycogen (starch) synthase activity | Any process that stops, prevents or reduces the frequency, rate or extent of glycogen (starch) synthase activity. |
GSK3B, INPP5K |