| GO ID | Ontology | GO Term | Term Definition |
Proteins |
GO:1904685 | BP | positive regulation of metalloendopeptidase activity | Any process that activates or increases the frequency, rate or extent of metalloendopeptidase activity. |
STAT3 |
GO:1904693 | BP | midbrain morphogenesis | The developmental process by which a midbrain is generated and organized. |
FZD6, SOS1 |
GO:1904694 | BP | negative regulation of vascular smooth muscle contraction | Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle contraction. |
ARHGAP42, DOCK5 |
GO:1904706 | BP | negative regulation of vascular smooth muscle cell proliferation | Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell proliferation. |
GSTP1, TPM1, HMOX1, IL10, CDKN1B, CNN1, GPER1 |
GO:1904707 | BP | positive regulation of vascular smooth muscle cell proliferation | Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell proliferation. |
JAK2, ERN1, AGT, PDGFB, MMP2, MMP9, NQO2, IL10, BMPR1A, MDM2, MAP3K5 |
GO:1904708 | BP | regulation of granulosa cell apoptotic process | Any process that modulates the frequency, rate or extent of granulosa cell apoptotic process. |
BOK |
GO:1904714 | BP | regulation of chaperone-mediated autophagy | Any process that modulates the frequency, rate or extent of chaperone-mediated autophagy. |
EEF1A1, EEF1A2, ATP13A2 |
GO:1904715 | BP | negative regulation of chaperone-mediated autophagy | Any process that stops, prevents or reduces the frequency, rate or extent of chaperone-mediated autophagy. |
SNCA |
GO:1904722 | BP | positive regulation of mRNA endonucleolytic cleavage involved in unfolded protein response | Any process that activates or increases the frequency, rate or extent of mRNA endonucleolytic cleavage involved in unfolded protein response. |
HSPA1A, HSPA1B |
GO:1904723 | BP | negative regulation of Wnt-Frizzled-LRP5/6 complex assembly | Any process that stops, prevents or reduces the frequency, rate or extent of Wnt-Frizzled-LRP5/6 complex assembly. |
DKK1 |
GO:1904733 | BP | negative regulation of electron carrier activity | Any process that stops, prevents or reduces the frequency, rate or extent of electron carrier activity. |
ETFBKMT |
GO:1904736 | BP | negative regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase | Any process that stops, prevents or reduces the frequency, rate or extent of fatty acid beta-oxidation using acyl-CoA dehydrogenase. |
ETFBKMT |
GO:1904743 | BP | negative regulation of telomeric DNA binding | Any process that stops, prevents or reduces the frequency, rate or extent of telomeric DNA binding. |
TNKS |
GO:1904753 | BP | negative regulation of vascular associated smooth muscle cell migration | Any process that stops, prevents or reduces the frequency, rate or extent of vascular associated smooth muscle cell migration. |
TPM1 |
GO:1904754 | BP | positive regulation of vascular associated smooth muscle cell migration | Any process that activates or increases the frequency, rate or extent of vascular associated smooth muscle cell migration. |
AGT, PDGFB, IQGAP1, MDM2, DOCK7, DOCK5 |
GO:1904761 | BP | negative regulation of myofibroblast differentiation | Any process that stops, prevents or reduces the frequency, rate or extent of myofibroblast differentiation. |
PDCD4 |
GO:1904762 | BP | positive regulation of myofibroblast differentiation | Any process that activates or increases the frequency, rate or extent of myofibroblast differentiation. |
PARP1 |
GO:1904772 | BP | response to tetrachloromethane | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetrachloromethane stimulus. |
EZH2 |
GO:1904792 | BP | positive regulation of telosome assembly | Any process that activates or increases the frequency, rate or extent of telosome assembly. |
TERF1 |
GO:1904793 | BP | regulation of euchromatin binding | Any process that modulates the frequency, rate or extent of euchromatin binding. |
CTNNB1 |
GO:1904796 | BP | regulation of core promoter binding | Any process that modulates the frequency, rate or extent of core promoter binding. |
CTNNB1 |
GO:1904808 | BP | positive regulation of protein oxidation | Any process that activates or increases the frequency, rate or extent of protein oxidation. |
TRABD2A |
GO:1904815 | BP | negative regulation of protein localization to chromosome, telomeric region | Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to chromosome, telomeric region. |
H2AFY |
GO:1904816 | BP | positive regulation of protein localization to chromosome, telomeric region | Any process that activates or increases the frequency, rate or extent of protein localization to chromosome, telomeric region. |
GNL3, GNL3L |
GO:1904823 | BP | purine nucleobase transmembrane transport | The directed movement of purine nucleobase across a membrane. |
AQP9, SLC28A3 |
GO:1904831 | BP | positive regulation of aortic smooth muscle cell differentiation | Any process that activates or increases the frequency, rate or extent of aortic smooth muscle cell differentiation. |
CTH |
GO:1904835 | BP | dorsal root ganglion morphogenesis | The developmental process by which a dorsal root ganglion is generated and organized. |
NRP1 |
GO:1904837 | BP | beta-catenin-TCF complex assembly | The aggregation, arrangement and bonding together of a set of components to form a beta-catenin-TCF complex. |
MYC, CTNNB1, SMARCA4, HIST1H4A, TLE1, TLE3, EP300, HDAC1, RBBP5, CREBBP, PYGO2, TCF7L1, TCF7L2, ASH2L, RUVBL1, TRRAP |
GO:1904843 | BP | cellular response to nitroglycerin | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitroglycerin stimulus. |
HSF1 |
GO:1904845 | BP | cellular response to L-glutamine | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-glutamine stimulus. |
CYBB, HSF1 |
GO:1904850 | BP | negative regulation of establishment of protein localization to telomere | Any process that stops, prevents or reduces the frequency, rate or extent of establishment of protein localization to telomere. |
TERF1 |
GO:1904851 | BP | positive regulation of establishment of protein localization to telomere | Any process that activates or increases the frequency, rate or extent of establishment of protein localization to telomere. |
DKC1, TCP1, CCT6A, CCT8, CCT2, CCT7 |
GO:1904861 | BP | excitatory synapse assembly | The aggregation, arrangement and bonding together of a set of components to form an excitatory synapse. |
WNT5A, NLGN1 |
GO:1904862 | BP | inhibitory synapse assembly | The aggregation, arrangement and bonding together of a set of components to form an inhibitory synapse. |
WNT5A |
GO:1904864 | BP | negative regulation of beta-catenin-TCF complex assembly | Any process that stops, prevents or reduces the frequency, rate or extent of beta-catenin-TCF complex assembly. |
DACT1 |
GO:1904871 | BP | positive regulation of protein localization to Cajal body | Any process that activates or increases the frequency, rate or extent of protein localization to Cajal body. |
TCP1, CCT6A, CCT3, CCT8, CCT2, CCT7 |
GO:1904874 | BP | positive regulation of telomerase RNA localization to Cajal body | Any process that activates or increases the frequency, rate or extent of telomerase RNA localization to Cajal body. |
DKC1, TCP1, CCT6A, CCT3, CCT8, CCT2, SHQ1, NAF1, CCT7, NOP10, RUVBL2, RUVBL1 |
GO:1904879 | BP | positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel | Any process that activates or increases the frequency, rate or extent of calcium ion transmembrane transport via high voltage-gated calcium channel. |
G6PD |
GO:1904885 | BP | beta-catenin destruction complex assembly | The aggregation, arrangement and bonding together of a set of components to form a beta-catenin destruction complex. |
AXIN1, APC, CSNK1A1, GSK3B |
GO:1904886 | BP | beta-catenin destruction complex disassembly | The disaggregation of a beta-catenin destruction complex into its constituent components. |
AXIN1, LRP5, LRP6, APC, CTNNB1, CSNK1A1, GSK3B, PPP1CA, CAV1 |
GO:1904888 | BP | cranial skeletal system development | The process whose specific outcome is the progression of a cranial skeletal system over time, from its formation to the mature structure. The cranial skeletal system is the skeletal subdivision of the head, and includes the skull (cranium plus mandible), pharyngeal and/or hyoid apparatus. |
CTNNB1, TGFB2 |
GO:1904903 | BP | ESCRT III complex disassembly | The disaggregation of an ESCRT III complex into its constituent components. |
CHMP2A, VPS4B, IST1, VTA1 |
GO:1904908 | BP | negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric | Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion, telomeric. |
TNKS, ATRX |
GO:1904911 | BP | negative regulation of establishment of RNA localization to telomere | Any process that stops, prevents or reduces the frequency, rate or extent of establishment of RNA localization to telomere. |
TERF1 |
GO:1904914 | BP | negative regulation of establishment of macromolecular complex localization to telomere | Any process that stops, prevents or reduces the frequency, rate or extent of establishment of macromolecular complex localization to telomere. |
TERF1 |
GO:1904928 | MF | coreceptor activity involved in canonical Wnt signaling pathway | Any coreceptor activity that is involved in a canonical Wnt signaling pathway. |
LRP5, LRP6 |
GO:1904929 | MF | coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway | Any coreceptor activity that is involved in Wnt signaling pathway, planar cell polarity pathway. |
GPC4, ROR1, PTK7, GPC6 |
GO:1904934 | BP | negative regulation of cell proliferation in midbrain | Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation in midbrain. |
WNT5A |
GO:1904938 | BP | planar cell polarity pathway involved in axon guidance | Any Wnt signaling pathway, planar cell polarity pathway that is involved in axon guidance. |
WNT5A, CELSR3 |
GO:1904948 | BP | midbrain dopaminergic neuron differentiation | The process in which a relatively unspecialized cell acquires the specialized features of a midbrain dopaminergic neuron. |
LRP6, WNT2, CTNNB1, NR4A2, RAC1 |
GO:1904953 | BP | Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation | Any Wnt signaling pathway that is involved in midbrain dopaminergic neuron differentiation. |
LRP6, WNT5A |
GO:1904954 | BP | canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation | Any canonical Wnt signaling pathway that is involved in midbrain dopaminergic neuron differentiation. |
WNT2, CTNNB1 |
GO:1904955 | BP | planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation | Any Wnt signaling pathway, planar cell polarity pathway that is involved in midbrain dopaminergic neuron differentiation. |
WNT5A |
GO:1904956 | BP | regulation of midbrain dopaminergic neuron differentiation | Any process that modulates the frequency, rate or extent of midbrain dopaminergic neuron differentiation. |
SFRP1 |
GO:1904958 | BP | positive regulation of midbrain dopaminergic neuron differentiation | Any process that activates or increases the frequency, rate or extent of midbrain dopaminergic neuron differentiation. |
DKK1 |
GO:1904980 | BP | positive regulation of endosome organization | Any process that activates or increases the frequency, rate or extent of endosome organization. |
SYNJ1 |
GO:1904988 | BP | negative regulation of endothelial cell activation | Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell activation. |
SOCS5 |
GO:1904996 | BP | positive regulation of leukocyte adhesion to vascular endothelial cell | Any process that activates or increases the frequency, rate or extent of leukocyte adhesion to vascular endothelial cell. |
TNF, ETS1 |
GO:1904998 | BP | negative regulation of leukocyte adhesion to arterial endothelial cell | Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte adhesion to arterial endothelial cell. |
KLF4 |
GO:1904999 | BP | positive regulation of leukocyte adhesion to arterial endothelial cell | Any process that activates or increases the frequency, rate or extent of leukocyte adhesion to arterial endothelial cell. |
TNF |
GO:1905006 | BP | negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation | Any process that stops, prevents or reduces the frequency, rate or extent of epithelial to mesenchymal transition involved in endocardial cushion formation. |
TGFB2 |
GO:1905007 | BP | positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation | Any process that activates or increases the frequency, rate or extent of epithelial to mesenchymal transition involved in endocardial cushion formation. |
TGFBR1, TGFBR2, TGFB2, ACVR1 |
GO:1905010 | BP | positive regulation of L-lysine import into cell | Any process that activates or increases the frequency, rate or extent of L-lysine import into cell. |
AGT |
GO:1905037 | BP | autophagosome organization | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an autophagosome. |
ATP13A2 |
GO:1905039 | BP | carboxylic acid transmembrane transport | The directed movement of carboxylic acid across a membrane. |
AQP9 |
GO:1905040 | BP | otic placode development | The process whose specific outcome is the progression of an otic placode over time, from its formation to the mature structure. |
NRP1 |
GO:1905053 | BP | positive regulation of base-excision repair | Any process that activates or increases the frequency, rate or extent of base-excision repair. |
FAM168A |
GO:1905064 | BP | negative regulation of vascular smooth muscle cell differentiation | Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell differentiation. |
PDGFB |
GO:1905065 | BP | positive regulation of vascular smooth muscle cell differentiation | Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell differentiation. |
KIT |
GO:1905075 | BP | positive regulation of occluding junction disassembly | Any process that activates or increases the frequency, rate or extent of occluding junction disassembly. |
TGFBR1 |
GO:1905090 | BP | negative regulation of parkin-mediated mitophagy in response to mitochondrial depolarization | Any process that stops, prevents or reduces the frequency, rate or extent of parkin-mediated mitophagy in response to mitochondrial depolarization. |
VPS13C |
GO:1905098 | BP | negative regulation of guanyl-nucleotide exchange factor activity | Any process that stops, prevents or reduces the frequency, rate or extent of guanyl-nucleotide exchange factor activity. |
EIF2S1 |
GO:1905103 | CC | integral component of lysosomal membrane | The component of the lysosome membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
ATP13A2 |
GO:1905122 | BP | polyamine import | The directed movement of polyamine macromolecule into a cell or organelle. |
ATP13A2 |
GO:1905123 | BP | regulation of glucosylceramidase activity | Any process that modulates the frequency, rate or extent of glucosylceramidase activity. |
ATP13A2 |
GO:1905143 | BP | eukaryotic translation initiation factor 2 complex assembly | The aggregation, arrangement and bonding together of a set of components to form an eukaryotic translation initiation factor 2 complex. |
CDC123 |
GO:1905150 | BP | regulation of voltage-gated sodium channel activity | Any process that modulates the frequency, rate or extent of voltage-gated sodium channel activity. |
FGF12 |
GO:1905154 | BP | negative regulation of membrane invagination | Any process that stops, prevents or reduces the frequency, rate or extent of membrane invagination. |
SYT11 |
GO:1905162 | BP | regulation of phagosome maturation | Any process that modulates the frequency, rate or extent of phagosome maturation. |
SYT11 |
GO:1905165 | BP | regulation of lysosomal protein catabolic process | Any process that modulates the frequency, rate or extent of lysosomal protein catabolic process. |
ATP13A2 |
GO:1905166 | BP | negative regulation of lysosomal protein catabolic process | Any process that stops, prevents or reduces the frequency, rate or extent of lysosomal protein catabolic process. |
ATP13A2 |
GO:1905171 | BP | positive regulation of protein localization to phagocytic vesicle | Any process that activates or increases the frequency, rate or extent of protein localization to phagocytic vesicle. |
SYT11 |
GO:1905176 | BP | positive regulation of vascular smooth muscle cell dedifferentiation | Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell dedifferentiation. |
PDGFB |
GO:1905202 | CC | methylcrotonoyl-CoA carboxylase complex | A protein complex which is capable of methylcrotonoyl-CoA carboxylase activity. |
MCCC1, MCCC2 |
GO:1905206 | BP | positive regulation of hydrogen peroxide-induced cell death | Any process that activates or increases the frequency, rate or extent of cell death in response to hydrogen peroxide. |
RIPK1 |
GO:1905223 | BP | epicardium morphogenesis | The developmental process by which an epicardium is generated and organized. |
TGFBR1 |
GO:1905259 | BP | negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway | Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to nitrosative stress. |
DNAJA1 |
GO:1905285 | BP | fibrous ring of heart morphogenesis | The developmental process by which a fibrous ring of heart is generated and organized. |
BMPR1A |
GO:1905305 | BP | negative regulation of cardiac myofibril assembly | Any process that stops, prevents or reduces the frequency, rate or extent of cardiac myofibril assembly. |
SMAD4 |
GO:1905313 | BP | transforming growth factor beta receptor signaling pathway involved in heart development | Any transforming growth factor beta receptor signaling pathway that is involved in heart development. |
TGFB1 |
GO:1905314 | BP | semi-lunar valve development | The process whose specific outcome is the progression of a semi-lunar valve over time, from its formation to the mature structure. |
BMPR2 |
GO:1905337 | BP | positive regulation of aggrephagy | Any process that activates or increases the frequency, rate or extent of aggrephagy. |
HTT |
GO:1905342 | BP | positive regulation of protein localization to kinetochore | Any process that activates or increases the frequency, rate or extent of protein localization to kinetochore. |
CENPQ |
GO:1905394 | MF | retromer complex binding | Interacting selectively and non-covalently with a retromer complex. |
RAB7A, TBC1D5 |
GO:1905408 | BP | negative regulation of creatine transmembrane transporter activity | Any process that stops, prevents or reduces the frequency, rate or extent of creatine transmembrane transporter activity. |
OSR1 |
GO:1905426 | BP | positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation | Any process that activates or increases the frequency, rate or extent of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation. |
CSNK1D, CSNK1E |
GO:1990000 | BP | amyloid fibril formation | The generation of amyloid fibrils, insoluble fibrous protein aggregates exhibiting beta sheet structure, from proteins. An example of this is seen when human RIP1 and RIP3 kinases form a heterodimeric functional amyloid signaling complex (PMID:22817896). |
APP, CD36, RIPK1 |
GO:1990001 | BP | inhibition of cysteine-type endopeptidase activity involved in apoptotic process | Any process that prevents the activation of an inactive cysteine-type endopeptidase involved in an apoptotic process. |
BIRC5, NOL3, XIAP, BIRC3, BCL2L12 |
GO:1990008 | CC | neurosecretory vesicle | A large cytoplasmic membrane-bounded vesicle with an electron dense granular core, up to 150-200 nm in diameter, found in neurosecretory cells in the hypothalamus. |
GNRH1 |
GO:1990023 | CC | mitotic spindle midzone | The area in the center of the anaphase spindle consisting of microtubules, microtubule bundling factors and kinesin motors where the spindle microtubules from opposite poles overlap in an antiparallel manner. |
EML1, CENPE, CTTN, MAP9, KIF18A, KIF20B |