Search Geneontologies

Geneontologies

GO ID Ontology GO Term Term Definition Proteins

GO:1903428

BP

positive regulation of reactive oxygen species biosynthetic process

Any process that activates or increases the frequency, rate or extent of reactive oxygen species biosynthetic process.

FOXO3, RAB27A, HDAC4

GO:1903429

BP

regulation of cell maturation

Any process that modulates the frequency, rate or extent of cell maturation.

KIF14

GO:1903432

BP

regulation of TORC1 signaling

Any process that modulates the frequency, rate or extent of TORC1 signaling.

RRAGC

GO:1903435

BP

positive regulation of constitutive secretory pathway

Any process that activates or increases the frequency, rate or extent of constitutive secretory pathway.

RAB27A

GO:1903438

BP

positive regulation of mitotic cytokinetic process

Any process that activates or increases the frequency, rate or extent of mitotic cytokinetic process.

KIF20B

GO:1903441

BP

protein localization to ciliary membrane

A process in which a protein is transported to, or maintained in, a location within a ciliary membrane.

RAB29, BBS2

GO:1903444

BP

negative regulation of brown fat cell differentiation

Any process that stops, prevents or reduces the frequency, rate or extent of brown fat cell differentiation.

TRPV4

GO:1903461

BP

Okazaki fragment processing involved in mitotic DNA replication

Any DNA replication, Okazaki fragment processing that is involved in mitotic cell cycle DNA replication.

LIG1

GO:1903489

BP

positive regulation of lactation

Any process that activates or increases the frequency, rate or extent of lactation.

XBP1

GO:1903506

BP

regulation of nucleic acid-templated transcription

Any process that modulates the frequency, rate or extent of nucleic acid-templated transcription.

AIP, ACTN4, ACTN1, ACTN2, FUS, NMI, TRIP11, TRIP13, PSMC3IP

GO:1903507

BP

negative regulation of nucleic acid-templated transcription

Any process that stops, prevents or reduces the frequency, rate or extent of nucleic acid-templated transcription.

SAP18, TFEC, SIAH2, CREG1, TDP2, PSMC3, YAP1, MXI1, HIRA, SRSF2, ZNF85, MTA1, TOB2, NPAT, CCAR1, TRIM22, DDX54, ZNF274, TONSL, NIF3L1, CDYL

GO:1903515

BP

calcium ion transport from cytosol to endoplasmic reticulum

The directed movement of calcium ion from cytosol to endoplasmic reticulum.

ATP2A2

GO:1903526

BP

negative regulation of membrane tubulation

Any process that stops, prevents or reduces the frequency, rate or extent of membrane tubulation.

WASL

GO:1903527

BP

positive regulation of membrane tubulation

Any process that activates or increases the frequency, rate or extent of membrane tubulation.

SH3GLB1

GO:1903531

BP

negative regulation of secretion by cell

Any process that stops, prevents or reduces the frequency, rate or extent of secretion by cell.

VAMP3

GO:1903533

BP

regulation of protein targeting

Any process that modulates the frequency, rate or extent of protein targeting.

NUCB1

GO:1903538

BP

regulation of meiotic cell cycle process involved in oocyte maturation

Any process that modulates the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation.

PPP2R1A

GO:1903542

BP

negative regulation of exosomal secretion

Any process that stops, prevents or reduces the frequency, rate or extent of exosomal secretion.

VPS4B

GO:1903543

BP

positive regulation of exosomal secretion

Any process that activates or increases the frequency, rate or extent of exosomal secretion.

SDCBP, CHMP2A, VPS4B, SDC1, SDC4, RAB7A, PDCD6IP, STAM, ATP13A2

GO:1903546

BP

protein localization to photoreceptor outer segment

A process in which a protein is transported to, or maintained in, a location within a photoreceptor outer segment.

TULP3, SPATA7

GO:1903551

BP

regulation of extracellular exosome assembly

Any process that modulates the frequency, rate or extent of extracellular vesicular exosome assembly.

PDCD6IP, STAM

GO:1903553

BP

positive regulation of extracellular exosome assembly

Any process that activates or increases the frequency, rate or extent of extracellular vesicular exosome assembly.

SDCBP, SDC1, SDC4, PDCD6IP

GO:1903561

CC

extracellular vesicle

Any vesicle that is part of the extracellular region.

SDCBP, EDIL3, EFEMP2, APOA1, APOE, FGA, FGB, TFRC, GNAI2, ATP1B1, ITGB2, SERPINE2, COL6A2, COL6A3, F5, PKM, CBR1, OGN, CD9, PCMT1, GRIA4, ATP1A2, SLC12A2, GNB1, TUBB4B, FBLN2, MFGE8, DNAJC3, TUBB2A, PDCD6IP, SLC5A5, COL12A1, OLFML3, CTSF, MAN1B1

GO:1903572

BP

positive regulation of protein kinase D signaling

Any process that activates or increases the frequency, rate or extent of protein kinase D signaling.

VEGFA

GO:1903575

BP

cornified envelope assembly

The aggregation, arrangement and bonding together of a set of components to form a cornified envelope.

STX2, DMKN

GO:1903576

BP

response to L-arginine

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-arginine stimulus.

DHODH

GO:1903579

BP

negative regulation of ATP metabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of ATP metabolic process.

TSPO

GO:1903586

BP

positive regulation of histone deubiquitination

Any process that activates or increases the frequency, rate or extent of histone deubiquitination.

SART3

GO:1903588

BP

negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis

Any process that stops, prevents or reduces the frequency, rate or extent of blood vessel endothelial cell proliferation involved in sprouting angiogenesis.

NGFR, PDCD10, DLL4

GO:1903595

BP

positive regulation of histamine secretion by mast cell

Any process that activates or increases the frequency, rate or extent of histamine secretion by mast cell.

SNX4, VAMP7

GO:1903597

BP

negative regulation of gap junction assembly

Any process that stops, prevents or reduces the frequency, rate or extent of gap junction assembly.

ACE

GO:1903598

BP

positive regulation of gap junction assembly

Any process that activates or increases the frequency, rate or extent of gap junction assembly.

AGT, CAV1

GO:1903599

BP

positive regulation of mitophagy

Any process that activates or increases the frequency, rate or extent of mitochondrion degradation.

HTT, HIF1A

GO:1903608

BP

protein localization to cytoplasmic stress granule

A process in which a protein is transported to, or maintained in, a location within a cytoplasmic stress granule.

DDX3X, SSB, TIA1, YBX1

GO:1903611

BP

negative regulation of calcium-dependent ATPase activity

Any process that stops, prevents or reduces the frequency, rate or extent of calcium-dependent ATPase activity.

RGN

GO:1903615

BP

positive regulation of protein tyrosine phosphatase activity

Any process that activates or increases the frequency, rate or extent of protein tyrosine phosphatase activity.

SLC39A10

GO:1903621

BP

protein localization to photoreceptor connecting cilium

A process in which a protein is transported to, or maintained in, a location within a photoreceptor connecting cilium.

SPATA7

GO:1903625

BP

negative regulation of DNA catabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of DNA catabolic process.

RGN

GO:1903629

BP

positive regulation of dUTP diphosphatase activity

Any process that activates or increases the frequency, rate or extent of dUTP diphosphatase activity.

RGN

GO:1903634

BP

negative regulation of leucine-tRNA ligase activity

Any process that stops, prevents or reduces the frequency, rate or extent of leucine-tRNA ligase activity.

RGN

GO:1903638

BP

positive regulation of protein import into mitochondrial outer membrane

Any process that activates or increases the frequency, rate or extent of protein import into mitochondrial outer membrane.

PDCD5

GO:1903640

BP

negative regulation of gastrin-induced gastric acid secretion

Any process that stops, prevents or reduces the frequency, rate or extent of gastrin-induced gastric acid secretion.

SCT

GO:1903645

BP

negative regulation of chaperone-mediated protein folding

Any process that stops, prevents or reduces the frequency, rate or extent of chaperone-mediated protein folding.

PDCD5

GO:1903660

BP

negative regulation of complement-dependent cytotoxicity

Any process that stops, prevents or reduces the frequency, rate or extent of complement-dependent cytotoxicity.

HSP90AB1

GO:1903671

BP

negative regulation of sprouting angiogenesis

Any process that stops, prevents or reduces the frequency, rate or extent of sprouting angiogenesis.

SYNJ2BP

GO:1903672

BP

positive regulation of sprouting angiogenesis

Any process that activates or increases the frequency, rate or extent of sprouting angiogenesis.

ITGA5, FGF2, JAK1

GO:1903673

BP

mitotic cleavage furrow formation

Any cleavage furrow formation that is involved in mitotic cell cycle.

RHOA

GO:1903679

BP

positive regulation of cap-independent translational initiation

Any process that activates or increases the frequency, rate or extent of cap-independent translational initiation.

YTHDF2

GO:1903690

BP

negative regulation of wound healing, spreading of epidermal cells

Any process that stops, prevents or reduces the frequency, rate or extent of wound healing, spreading of epidermal cells.

PHLDB2

GO:1903701

BP

substantia propria of cornea development

The process whose specific outcome is the progression of a substantia propria of cornea over time, from its formation to the mature structure.

TGFB2

GO:1903715

BP

regulation of aerobic respiration

Any process that modulates the frequency, rate or extent of aerobic respiration.

VCP, BNIP3, HIF1A

GO:1903723

BP

negative regulation of centriole elongation

Any process that stops, prevents or reduces the frequency, rate or extent of centriole elongation.

CHMP2A

GO:1903724

BP

positive regulation of centriole elongation

Any process that activates or increases the frequency, rate or extent of centriole elongation.

VPS4B

GO:1903725

BP

regulation of phospholipid metabolic process

Any process that modulates the frequency, rate or extent of phospholipid metabolic process.

ARF1

GO:1903748

BP

negative regulation of establishment of protein localization to mitochondrion

Any process that stops, prevents or reduces the frequency, rate or extent of establishment of protein localization to mitochondrion.

DNAJA1, HSPH1

GO:1903751

BP

negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide

Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to hydrogen peroxide.

HSPH1, PINK1

GO:1903753

BP

negative regulation of p38MAPK cascade

Any process that stops, prevents or reduces the frequency, rate or extent of p38MAPK cascade.

EZR, DLG1, HSPH1, PTPN22

GO:1903755

BP

positive regulation of SUMO transferase activity

Any process that activates or increases the frequency, rate or extent of SUMO transferase activity.

UBE2I

GO:1903759

BP

signal transduction involved in regulation of aerobic respiration

Any signal transduction that is involved in regulation of aerobic respiration.

TRPV4

GO:1903763

MF

gap junction channel activity involved in cell communication by electrical coupling

Any gap junction channel activity that is involved in cell communication by electrical coupling.

GJA1

GO:1903772

BP

regulation of viral budding via host ESCRT complex

Any process that modulates the frequency, rate or extent of viral budding via host ESCRT complex.

MVB12A

GO:1903778

BP

protein localization to vacuolar membrane

A process in which a protein is transported to, or maintained in, a location within a vacuolar membrane.

SH3GLB1

GO:1903779

BP

regulation of cardiac conduction

Any process that modulates the frequency, rate or extent of cardiac conduction.

FXYD1, AHCYL1, AGT, ATP1B1, ATP2A2, PRKACA, TNNI3, ATP2B1, NPR2, ATP2B4, PLN, TRPC1, ATP1A2, ATP1B3, FXYD4, DMPK, ASPH, ITPR2, ITPR3, ITPR1, KCNJ11, RYR3, TMEM65, RYR2, EHD3

GO:1903799

BP

negative regulation of production of miRNAs involved in gene silencing by miRNA

Any process that stops, prevents or reduces the frequency, rate or extent of production of miRNAs involved in gene silencing by miRNA.

NCOR1, TGFB1, ESR1, NCOR2

GO:1903800

BP

positive regulation of production of miRNAs involved in gene silencing by miRNA

Any process that activates or increases the frequency, rate or extent of production of miRNAs involved in gene silencing by miRNA.

EGFR, MAP2K2, MAP2K1

GO:1903827

BP

regulation of cellular protein localization

Any process that modulates the frequency, rate or extent of cellular protein localization. Cellular protein localization is any process in which a protein is transported to, and/or maintained in, a specific location and encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell.

STX6, KDM1A, PARP1, WNT5A, CSNK1E

GO:1903828

BP

negative regulation of cellular protein localization

Any process that stops, prevents or reduces the frequency, rate or extent of cellular protein localization. Cellular protein localization is any process in which a protein is transported to, and/or maintained in, a specific location and encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell.

TP53INP2

GO:1903829

BP

positive regulation of cellular protein localization

Any process that activates or increases the frequency, rate or extent of cellular protein localization. Cellular protein localization is any process in which a protein is transported to, and/or maintained in, a specific location and encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell.

IQGAP1

GO:1903830

BP

magnesium ion transmembrane transport

The directed movement of magnesium ion across a membrane.

ZDHHC17, NIPA2, SLC41A2, CNNM2

GO:1903849

BP

positive regulation of aorta morphogenesis

Any process that activates or increases the frequency, rate or extent of aorta morphogenesis.

NOTCH1, EFNB2

GO:1903852

BP

positive regulation of cristae formation

Any process that activates or increases the frequency, rate or extent of cristae formation.

PINK1

GO:1903861

BP

positive regulation of dendrite extension

Any process that activates or increases the frequency, rate or extent of dendrite extension.

PARK2, SYT1, CPNE9, NEDD4L, ITSN2, RIMS2

GO:1903862

BP

positive regulation of oxidative phosphorylation

Any process that activates or increases the frequency, rate or extent of oxidative phosphorylation.

VCP, GADD45GIP1

GO:1903874

BP

ferrous iron transmembrane transport

The directed movement of ferrous iron (iron(2+)) across a membrane.

SLC11A2, SLC39A14, SLC25A37

GO:1903887

BP

motile primary cilium assembly

The aggregation, arrangement and bonding together of a set of components to form a motile primary cilium.

CENPJ, MKS1, CC2D2A, INTU

GO:1903891

BP

regulation of ATF6-mediated unfolded protein response

Any process that modulates the frequency, rate or extent of the ATF6-mediated unfolded protein response.

HSPA5

GO:1903894

BP

regulation of IRE1-mediated unfolded protein response

Any process that modulates the frequency, rate or extent of the IRE1-mediated unfolded protein response.

HSPA5

GO:1903896

BP

positive regulation of IRE1-mediated unfolded protein response

Any process that activates or increases the frequency, rate or extent of the IRE1-mediated unfolded protein response.

BCL2L11, BAX

GO:1903897

BP

regulation of PERK-mediated unfolded protein response

Any process that modulates the frequency, rate or extent of the PERK-mediated unfolded protein response.

HSPA5

GO:1903898

BP

negative regulation of PERK-mediated unfolded protein response

Any process that stops, prevents or reduces the frequency, rate or extent of the PERK-mediated unfolded protein response.

PPP1R15A

GO:1903899

BP

positive regulation of PERK-mediated unfolded protein response

Any process that activates or increases the frequency, rate or extent of the PERK-mediated unfolded protein response.

PTPN2

GO:1903900

BP

regulation of viral life cycle

Any process that modulates the frequency, rate or extent of viral life cycle.

LAMP3

GO:1903902

BP

positive regulation of viral life cycle

Any process that activates or increases the frequency, rate or extent of viral life cycle.

VPS4B

GO:1903911

BP

positive regulation of receptor clustering

Any process that activates or increases the frequency, rate or extent of receptor clustering.

TGFB1

GO:1903912

BP

negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation

Any process that stops, prevents or reduces the frequency, rate or extent of endoplasmic reticulum stress-induced eiF2alpha phosphorylation.

PPP1R15A, DNAJC3

GO:1903917

BP

positive regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation

Any process that activates or increases the frequency, rate or extent of endoplasmic reticulum stress-induced eIF2alpha dephosphorylation.

PPP1R15A

GO:1903919

BP

negative regulation of actin filament severing

Any process that stops, prevents or reduces the frequency, rate or extent of actin filament severing.

MYH9

GO:1903923

BP

positive regulation of protein processing in phagocytic vesicle

Any process that activates or increases the frequency, rate or extent of protein processing in phagocytic vesicle.

MYH9

GO:1903949

BP

positive regulation of atrial cardiac muscle cell action potential

Any process that activates or increases the frequency, rate or extent of atrial cardiac muscle cell action potential.

TRPM4

GO:1903955

BP

positive regulation of protein targeting to mitochondrion

Any process that activates or increases the frequency, rate or extent of protein targeting to mitochondrion.

LEPROT, FAM20B, ATG13, ABLIM3, ACTL6A, RNASE2, RAC2, ITGAX, HSPA1L, CTSK, RPL28, HNMT, NPEPPS, UBE2D3, MYBPC1, IL9R, NRG1, SREBF2, ZBTB17, HES1, UGCG, RHOU, HUWE1, UBE2J2, NKAP, BAP1, LRRC46, ZBED3, PINK1, EPT1, NBPF3, HPS4, STARD7, MIS18A, TOMM7, USP36, SAE1, PEMT, RUVBL1, SH3GLB1

GO:1903959

BP

regulation of anion transmembrane transport

Any process that modulates the frequency, rate or extent of anion transmembrane transport.

GPR89A, GPR89B, VDAC2, CLCN3, CLCN4, CLCN5, CLCN6, CLCN7, CLCNKA, CLCNKB, ANO6, VDAC3

GO:1903966

BP

monounsaturated fatty acid biosynthetic process

The chemical reactions and pathways resulting in the formation of monounsaturated fatty acid.

SCD

GO:1903984

BP

positive regulation of TRAIL-activated apoptotic signaling pathway

Any process that activates or increases the frequency, rate or extent of TRAIL-activated apoptotic signaling pathway.

ATF3, TIMP3, PTEN

GO:1903988

BP

ferrous iron export

The directed movement of iron(2+) out of a cell or organelle.

SLC40A1

GO:1903991

BP

positive regulation of ferrous iron import into cell

Any process that activates or increases the frequency, rate or extent of ferrous iron import into cell.

B2M, HFE

GO:1903999

BP

negative regulation of eating behavior

Any process that stops, prevents or reduces the frequency, rate or extent of eating behavior.

NAPEPLD

GO:1904012

MF

platinum binding

Interacting selectively and non-covalently with platinum.

HRSP12

GO:1904013

MF

xenon atom binding

Interacting selectively and non-covalently with xenon atom.

HRSP12

GO:1904017

BP

cellular response to Thyroglobulin triiodothyronine

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Thyroglobulin triiodothyronine stimulus.

NCOA2, NCOA1

GO:1904031

BP

positive regulation of cyclin-dependent protein kinase activity

Any process that activates or increases the frequency, rate or extent of cyclin-dependent protein kinase activity.

CDKN1A

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