| GO ID | Ontology | GO Term | Term Definition |
Proteins |
GO:1902953 | BP | positive regulation of ER to Golgi vesicle-mediated transport | Any process that activates or increases the frequency, rate or extent of ER to Golgi vesicle-mediated transport. |
ARF1, SORL1 |
GO:1902955 | BP | positive regulation of early endosome to recycling endosome transport | Any process that activates or increases the frequency, rate or extent of early endosome to recycling endosome transport. |
SORL1 |
GO:1902957 | BP | negative regulation of mitochondrial electron transport, NADH to ubiquinone | Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial electron transport, NADH to ubiquinone. |
SNCA, DNAJC15 |
GO:1902958 | BP | positive regulation of mitochondrial electron transport, NADH to ubiquinone | Any process that activates or increases the frequency, rate or extent of mitochondrial electron transport, NADH to ubiquinone. |
PINK1 |
GO:1902959 | BP | regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process | Any process that modulates the frequency, rate or extent of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process. |
PICALM |
GO:1902960 | BP | negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process | Any process that stops, prevents or reduces the frequency, rate or extent of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process. |
SORL1 |
GO:1902961 | BP | positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process | Any process that activates or increases the frequency, rate or extent of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process. |
PICALM |
GO:1902963 | BP | negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process | Any process that stops, prevents or reduces the frequency, rate or extent of metalloendopeptidase activity involved in amyloid precursor protein catabolic process. |
PICALM, SORL1 |
GO:1902966 | BP | positive regulation of protein localization to early endosome | Any process that activates or increases the frequency, rate or extent of protein localization to early endosome. |
EZR, RDX, SORL1 |
GO:1902975 | BP | mitotic DNA replication initiation | Any DNA replication initiation involved in mitotic cell cycle DNA replication. |
GINS2 |
GO:1902979 | BP | mitotic DNA replication termination | Any DNA replication termination involved in mitotic cell cycle DNA replication. |
RTFDC1 |
GO:1902983 | BP | DNA strand elongation involved in mitotic DNA replication | Any DNA strand elongation involved in mitotic cell cycle DNA replication. |
GINS1 |
GO:1902990 | BP | mitotic telomere maintenance via semi-conservative replication | Any telomere maintenance via semi-conservative replication that is involved in mitotic cell cycle. |
PCNA, DNA2 |
GO:1902995 | BP | positive regulation of phospholipid efflux | Any process that activates or increases the frequency, rate or extent of phospholipid efflux. |
APOE |
GO:1902997 | BP | negative regulation of neurofibrillary tangle assembly | Any process that stops, prevents or reduces the frequency, rate or extent of neurofibrillary tangle assembly. |
SORL1 |
GO:1902998 | BP | positive regulation of neurofibrillary tangle assembly | Any process that activates or increases the frequency, rate or extent of neurofibrillary tangle assembly. |
CLU |
GO:1903002 | BP | positive regulation of lipid transport across blood brain barrier | Any process that activates or increases the frequency, rate or extent of lipid transport across blood brain barrier. |
APOE |
GO:1903003 | BP | positive regulation of protein deubiquitination | Any process that activates or increases the frequency, rate or extent of protein deubiquitination. |
TANK |
GO:1903006 | BP | positive regulation of protein K63-linked deubiquitination | Any process that activates or increases the frequency, rate or extent of protein K63-linked deubiquitination. |
VCP |
GO:1903007 | BP | positive regulation of Lys63-specific deubiquitinase activity | Any process that activates or increases the frequency, rate or extent of Lys63-specific deubiquitinase activity. |
VCP |
GO:1903010 | BP | regulation of bone development | Any process that modulates the frequency, rate or extent of bone development. |
GLI3 |
GO:1903011 | BP | negative regulation of bone development | Any process that stops, prevents or reduces the frequency, rate or extent of bone development. |
RGN |
GO:1903016 | BP | negative regulation of exo-alpha-sialidase activity | Any process that stops, prevents or reduces the frequency, rate or extent of exo-alpha-sialidase activity. |
APCS, PTX3 |
GO:1903019 | BP | negative regulation of glycoprotein metabolic process | Any process that stops, prevents or reduces the frequency, rate or extent of glycoprotein metabolic process. |
APCS, PTX3 |
GO:1903020 | BP | positive regulation of glycoprotein metabolic process | Any process that activates or increases the frequency, rate or extent of glycoprotein metabolic process. |
RAB1A, RAB1B |
GO:1903025 | BP | regulation of RNA polymerase II regulatory region sequence-specific DNA binding | Any process that modulates the frequency, rate or extent of RNA polymerase II regulatory region sequence-specific DNA binding. |
LIF |
GO:1903026 | BP | negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding | Any process that stops, prevents or reduces the frequency, rate or extent of RNA polymerase II regulatory region sequence-specific DNA binding. |
DDIT3, ID1 |
GO:1903033 | BP | positive regulation of microtubule plus-end binding | Any process that activates or increases the frequency, rate or extent of microtubule plus-end binding. |
MAPRE1, MAPRE3 |
GO:1903034 | BP | regulation of response to wounding | Any process that modulates the frequency, rate or extent of response to wounding. |
IL10 |
GO:1903038 | BP | negative regulation of leukocyte cell-cell adhesion | Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte cell-cell adhesion. |
ASS1, PPARA |
GO:1903044 | BP | protein localization to membrane raft | A process in which a protein is transported to, or maintained in, a location within a membrane raft. |
FLOT1, RFTN1 |
GO:1903045 | BP | neural crest cell migration involved in sympathetic nervous system development | Any neural crest cell migration that is involved in sympathetic nervous system development. |
SEMA3A |
GO:1903047 | BP | mitotic cell cycle process | A process that is part of the mitotic cell cycle. |
KIF14 |
GO:1903052 | BP | positive regulation of proteolysis involved in cellular protein catabolic process | Any process that activates or increases the frequency, rate or extent of proteolysis involved in cellular protein catabolic process. |
CTSC, RGN |
GO:1903053 | BP | regulation of extracellular matrix organization | Any process that modulates the frequency, rate or extent of extracellular matrix organization. |
TCF15 |
GO:1903056 | BP | regulation of melanosome organization | Any process that modulates the frequency, rate or extent of melanosome organization. |
ZEB2 |
GO:1903061 | BP | positive regulation of protein lipidation | Any process that activates or increases the frequency, rate or extent of protein lipidation. |
RAB3GAP1, SVIP, RAB3GAP2 |
GO:1903070 | BP | negative regulation of ER-associated ubiquitin-dependent protein catabolic process | Any process that stops, prevents or reduces the frequency, rate or extent of ER-associated ubiquitin-dependent protein catabolic process. |
SVIP |
GO:1903071 | BP | positive regulation of ER-associated ubiquitin-dependent protein catabolic process | Any process that activates or increases the frequency, rate or extent of ER-associated ubiquitin-dependent protein catabolic process. |
SGTA, BCAP31, CAV1 |
GO:1903076 | BP | regulation of protein localization to plasma membrane | Any process that modulates the frequency, rate or extent of protein localization to plasma membrane. |
STX7, GBP1, SPTBN1, VTI1B |
GO:1903077 | BP | negative regulation of protein localization to plasma membrane | Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to plasma membrane. |
TGFB1, GBP1, NUMB, DAB2, AP2M1 |
GO:1903078 | BP | positive regulation of protein localization to plasma membrane | Any process that activates or increases the frequency, rate or extent of protein localization to plasma membrane. |
SPTBN1, STX4, STX3 |
GO:1903126 | BP | negative regulation of centriole-centriole cohesion | Any process that stops, prevents or reduces the frequency, rate or extent of centriole-centriole cohesion. |
NEK2 |
GO:1903135 | MF | cupric ion binding | Interacting selectively and non-covalently with cupric ion, copper(2+). |
ATP13A2 |
GO:1903140 | BP | regulation of establishment of endothelial barrier | Any process that modulates the frequency, rate or extent of establishment of endothelial barrier. |
ROCK2, TNF, IL1B |
GO:1903141 | BP | negative regulation of establishment of endothelial barrier | Any process that stops, prevents or reduces the frequency, rate or extent of establishment of endothelial barrier. |
S1PR3 |
GO:1903142 | BP | positive regulation of establishment of endothelial barrier | Any process that activates or increases the frequency, rate or extent of establishment of endothelial barrier. |
CDH5 |
GO:1903146 | BP | regulation of mitophagy | Any process that modulates the frequency, rate or extent of mitochondrion degradation (mitophagy). |
HAX1, BNIP3L, ACTL6A, SREBF1, CTSK, RPL28, SREBF2, ZBTB17, CTTN, PINK1, MAP1LC3B, ATP13A2, USP36, HDAC6, RUVBL1 |
GO:1903147 | BP | negative regulation of mitophagy | Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrion degradation (mitophagy). |
TSPO, PINK1 |
GO:1903169 | BP | regulation of calcium ion transmembrane transport | Any process that modulates the frequency, rate or extent of calcium ion transmembrane transport. |
TSPAN13, PIK3CG |
GO:1903170 | BP | negative regulation of calcium ion transmembrane transport | Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion transmembrane transport. |
ATP1A2 |
GO:1903202 | BP | negative regulation of oxidative stress-induced cell death | Any process that stops, prevents or reduces the frequency, rate or extent of oxidative stress-induced cell death. |
PARK2, PINK1 |
GO:1903204 | BP | negative regulation of oxidative stress-induced neuron death | Any process that stops, prevents or reduces the frequency, rate or extent of oxidative stress-induced neuron death. |
ATF4, PINK1 |
GO:1903206 | BP | negative regulation of hydrogen peroxide-induced cell death | Any process that stops, prevents or reduces the frequency, rate or extent of hydrogen peroxide-induced cell death. |
GPR37, PSAP, TXN, NUP93 |
GO:1903208 | BP | negative regulation of hydrogen peroxide-induced neuron death | Any process that stops, prevents or reduces the frequency, rate or extent of hydrogen peroxide-induced neuron death. |
RACK1, NR4A3 |
GO:1903214 | BP | regulation of protein targeting to mitochondrion | Any process that modulates the frequency, rate or extent of protein targeting to mitochondrion. |
HAX1, BNIP3L, PARK2, SREBF1, PINK1 |
GO:1903225 | BP | negative regulation of endodermal cell differentiation | Any process that stops, prevents or reduces the frequency, rate or extent of endodermal cell differentiation. |
COL5A2, COL5A1 |
GO:1903232 | BP | melanosome assembly | The aggregation, arrangement and bonding together of a set of components to form a melanosome, a tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored. |
TRAPPC6A, RAB32, HPS1, HPS4 |
GO:1903233 | BP | regulation of calcium ion-dependent exocytosis of neurotransmitter | Any process that modulates the frequency, rate or extent of calcium ion-dependent exocytosis of neurotransmitter. |
ATP2A2, RAB3GAP1 |
GO:1903237 | BP | negative regulation of leukocyte tethering or rolling | Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte tethering or rolling. |
CXCL12 |
GO:1903238 | BP | positive regulation of leukocyte tethering or rolling | Any process that activates or increases the frequency, rate or extent of leukocyte tethering or rolling. |
PTAFR |
GO:1903242 | BP | regulation of cardiac muscle hypertrophy in response to stress | Any process that modulates the frequency, rate or extent of cardiac muscle hypertrophy in response to stress. |
BMP10 |
GO:1903243 | BP | negative regulation of cardiac muscle hypertrophy in response to stress | Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle hypertrophy in response to stress. |
ATP2B4, ERRFI1 |
GO:1903244 | BP | positive regulation of cardiac muscle hypertrophy in response to stress | Any process that activates or increases the frequency, rate or extent of cardiac muscle hypertrophy in response to stress. |
PPP3CA, TRPC3 |
GO:1903249 | BP | negative regulation of citrulline biosynthetic process | Any process that stops, prevents or reduces the frequency, rate or extent of citrulline biosynthetic process. |
ATP2B4 |
GO:1903262 | BP | negative regulation of serine phosphorylation of STAT3 protein | Any process that stops, prevents or reduces the frequency, rate or extent of serine phosphorylation of STAT3 protein. |
PWP1 |
GO:1903265 | BP | positive regulation of tumor necrosis factor-mediated signaling pathway | Any process that activates or increases the frequency, rate or extent of tumor necrosis factor-mediated signaling pathway. |
PARK2, HSPA1A, HSPA1B |
GO:1903278 | BP | positive regulation of sodium ion export from cell | Any process that activates or increases the frequency, rate or extent of sodium ion export from cell. |
FXYD1, ATP1B1, ATP1B3 |
GO:1903280 | BP | negative regulation of calcium:sodium antiporter activity | Any process that stops, prevents or reduces the frequency, rate or extent of calcium:sodium antiporter activity. |
ATP1A2 |
GO:1903281 | BP | positive regulation of calcium:sodium antiporter activity | Any process that activates or increases the frequency, rate or extent of calcium:sodium antiporter activity. |
ATP1B1 |
GO:1903284 | BP | positive regulation of glutathione peroxidase activity | Any process that activates or increases the frequency, rate or extent of glutathione peroxidase activity. |
SNCA |
GO:1903285 | BP | positive regulation of hydrogen peroxide catabolic process | Any process that activates or increases the frequency, rate or extent of hydrogen peroxide catabolic process. |
SNCA |
GO:1903288 | BP | positive regulation of potassium ion import | Any process that activates or increases the frequency, rate or extent of potassium ion import. |
ATP1B1, ATP1B3 |
GO:1903298 | BP | negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway | Any process that stops, prevents or reduces the frequency, rate or extent of hypoxia-induced intrinsic apoptotic signaling pathway. |
PINK1, HYOU1 |
GO:1903305 | BP | regulation of regulated secretory pathway | Any process that modulates the frequency, rate or extent of regulated secretory pathway. |
SYT1 |
GO:1903307 | BP | positive regulation of regulated secretory pathway | Any process that activates or increases the frequency, rate or extent of regulated secretory pathway. |
RAB27A |
GO:1903319 | BP | positive regulation of protein maturation | Any process that activates or increases the frequency, rate or extent of protein maturation. |
TFR2 |
GO:1903347 | BP | negative regulation of bicellular tight junction assembly | Any process that stops, prevents or reduces the frequency, rate or extent of tight junction assembly. |
ROCK2, TNF |
GO:1903348 | BP | positive regulation of bicellular tight junction assembly | Any process that activates or increases the frequency, rate or extent of tight junction assembly. |
NPHP1 |
GO:1903351 | BP | cellular response to dopamine | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dopamine stimulus. |
PARK2, ID1, HDAC2 |
GO:1903352 | BP | L-ornithine transmembrane transport | The directed movement of L-ornithine across a membrane. |
SLC25A15 |
GO:1903358 | BP | regulation of Golgi organization | Any process that modulates the frequency, rate or extent of Golgi organization. |
USP6NL, EHD3 |
GO:1903361 | BP | protein localization to basolateral plasma membrane | A process in which a protein is transported to, or maintained in, a location within a basolateral plasma membrane. |
CAV1, PDZD11, LIN7B, LIN7C |
GO:1903364 | BP | positive regulation of cellular protein catabolic process | Any process that activates or increases the frequency, rate or extent of cellular protein catabolic process. |
EZR, TNFAIP3, RDX, PTTG1IP, UQCC2, DACT1 |
GO:1903373 | BP | positive regulation of endoplasmic reticulum tubular network organization | Any process that activates or increases the frequency, rate or extent of endoplasmic reticulum tubular network organization. |
RAB3GAP1, RAB3GAP2 |
GO:1903375 | BP | facioacoustic ganglion development | The process whose specific outcome is the progression of an acoustico-facial VII-VIII ganglion complex over time, from its formation to the mature structure. |
NRP1, SEMA3A |
GO:1903376 | BP | regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway | Any process that modulates the frequency, rate or extent of oxidative stress-induced neuron intrinsic apoptotic signaling pathway. |
PARP1 |
GO:1903377 | BP | negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway | Any process that stops, prevents or reduces the frequency, rate or extent of oxidative stress-induced neuron intrinsic apoptotic signaling pathway. |
PARK2, NONO, HIF1A |
GO:1903378 | BP | positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway | Any process that activates or increases the frequency, rate or extent of oxidative stress-induced neuron intrinsic apoptotic signaling pathway. |
PARK2, MCL1 |
GO:1903382 | BP | negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway | Any process that stops, prevents or reduces the frequency, rate or extent of an endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway. |
PARK2, HYOU1 |
GO:1903384 | BP | negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway | Any process that stops, prevents or reduces the frequency, rate or extent of a hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway. |
PINK1 |
GO:1903392 | BP | negative regulation of adherens junction organization | Any process that stops, prevents or reduces the frequency, rate or extent of adherens junction organization. |
RDX |
GO:1903403 | BP | negative regulation of renal phosphate excretion | Any process that stops, prevents or reduces the frequency, rate or extent of renal phosphate excretion. |
STC1 |
GO:1903409 | BP | reactive oxygen species biosynthetic process | The chemical reactions and pathways resulting in the formation of reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen. |
GBF1 |
GO:1903413 | BP | cellular response to bile acid | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bile acid stimulus. |
HAMP |
GO:1903416 | BP | response to glycoside | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycoside stimulus. |
ATP1A2 |
GO:1903420 | BP | protein localization to endoplasmic reticulum tubular network | A process in which a protein is transported to, or maintained in, a location within an endoplasmic reticulum tubular network. |
GBF1 |
GO:1903421 | BP | regulation of synaptic vesicle recycling | Any process that modulates the frequency, rate or extent of synaptic vesicle recycling. |
SNCA, CDK5, FGF14 |
GO:1903426 | BP | regulation of reactive oxygen species biosynthetic process | Any process that modulates the frequency, rate or extent of reactive oxygen species biosynthetic process. |
SNCA |
GO:1903427 | BP | negative regulation of reactive oxygen species biosynthetic process | Any process that stops, prevents or reduces the frequency, rate or extent of reactive oxygen species biosynthetic process. |
HSPD1, SLC18A2 |