Search Geneontologies

Geneontologies

GO ID Ontology GO Term Term Definition Proteins

GO:1901863

BP

positive regulation of muscle tissue development

Any process that activates or increases the frequency, rate or extent of muscle tissue development.

PPARGC1A

GO:1901874

BP

negative regulation of post-translational protein modification

Any process that stops, prevents or reduces the frequency, rate or extent of post-translational protein modification.

CRTAP, FLCN

GO:1901877

BP

negative regulation of calcium ion binding

Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion binding.

PLN

GO:1901888

BP

regulation of cell junction assembly

Any process that modulates the frequency, rate or extent of cell junction assembly.

RAP1A, RAPGEF1

GO:1901890

BP

positive regulation of cell junction assembly

Any process that activates or increases the frequency, rate or extent of cell junction assembly.

FLOT1

GO:1901894

BP

regulation of calcium-transporting ATPase activity

Any process that modulates the frequency, rate or extent of calcium-transporting ATPase activity.

PLN

GO:1901895

BP

negative regulation of calcium-transporting ATPase activity

Any process that stops, prevents or reduces the frequency, rate or extent of calcium-transporting ATPase activity.

PLN

GO:1901896

BP

positive regulation of calcium-transporting ATPase activity

Any process that activates or increases the frequency, rate or extent of calcium-transporting ATPase activity.

RGN, RYR2

GO:1901897

BP

regulation of relaxation of cardiac muscle

Any process that modulates the frequency, rate or extent of relaxation of cardiac muscle.

PLN, CAMK2D

GO:1901898

BP

negative regulation of relaxation of cardiac muscle

Any process that stops, prevents or reduces the frequency, rate or extent of relaxation of cardiac muscle.

PDE4D

GO:1901907

BP

diadenosine pentaphosphate catabolic process

The chemical reactions and pathways resulting in the breakdown of diadenosine pentaphosphate.

NUDT3, NUDT10, NUDT11

GO:1901909

BP

diadenosine hexaphosphate catabolic process

The chemical reactions and pathways resulting in the breakdown of diadenosine hexaphosphate.

NUDT3, NUDT10, NUDT11

GO:1901911

BP

adenosine 5'-(hexahydrogen pentaphosphate) catabolic process

The chemical reactions and pathways resulting in the breakdown of adenosine 5'-(hexahydrogen pentaphosphate).

NUDT3, NUDT10, NUDT11

GO:1901962

BP

S-adenosyl-L-methionine transmembrane transport

The directed movement of S-adenosyl-L-methionine across a membrane.

SLC25A26

GO:1901964

BP

positive regulation of cell proliferation involved in outflow tract morphogenesis

Any process that activates or increases the frequency, rate or extent of cell proliferation involved in outflow tract morphogenesis.

BMP4

GO:1901970

BP

positive regulation of mitotic sister chromatid separation

Any process that activates or increases the frequency, rate or extent of mitotic sister chromatid separation.

ESPL1

GO:1901976

BP

regulation of cell cycle checkpoint

Any process that modulates the frequency, rate or extent of cell cycle checkpoint.

AKT1

GO:1901978

BP

positive regulation of cell cycle checkpoint

Any process that activates or increases the frequency, rate or extent of cell cycle checkpoint.

PROX1

GO:1901979

BP

regulation of inward rectifier potassium channel activity

Any process that modulates the frequency, rate or extent of inward rectifier potassium channel activity.

CAV1

GO:1901981

MF

phosphatidylinositol phosphate binding

Interacting selectively and non-covalently with phosphatidylinositol phosphate.

GAP43, PLCD1, FGD2, DENND1A, ANKFY1

GO:1901985

BP

positive regulation of protein acetylation

Any process that activates or increases the frequency, rate or extent of protein acetylation.

CAMK1

GO:1901989

BP

positive regulation of cell cycle phase transition

Any process that activates or increases the frequency, rate or extent of cell cycle phase transition.

CDCA5

GO:1901990

BP

regulation of mitotic cell cycle phase transition

Any process that modulates the frequency, rate or extent of mitotic cell cycle phase transition.

ERCC2, XPC, NEK11

GO:1901991

BP

negative regulation of mitotic cell cycle phase transition

Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cell cycle phase transition.

ZFP36L2, ZFP36L1, TPRA1, RGCC

GO:1901998

BP

toxin transport

The directed movement of a toxin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

ARID1A, NRP1, LRP6, SLC22A3, HSPA5, TCP1, CASP1, DNAJA1, CCT3, CCT8, RAB28, ANTXR2, COPZ1, CCT2, BNIP3, ATP6V0A1, CCT7, SLC7A8, GGA1

GO:1902003

BP

regulation of beta-amyloid formation

Any process that modulates the frequency, rate or extent of beta-amyloid formation.

TMED10

GO:1902004

BP

positive regulation of beta-amyloid formation

Any process that activates or increases the frequency, rate or extent of beta-amyloid formation.

GSAP, CLU, CSNK1E, PICALM

GO:1902010

BP

negative regulation of translation in response to endoplasmic reticulum stress

Any process that stops, prevents, or reduces the frequency, rate or extent of translation as a result of endoplasmic reticulum stress.

SESN2

GO:1902017

BP

regulation of cilium assembly

Any process that modulates the frequency, rate or extent of cilium assembly.

CYLD, DCDC2, VDAC3

GO:1902018

BP

negative regulation of cilium assembly

Any process that stops, prevents or reduces the frequency, rate or extent of cilium assembly.

EVI5L

GO:1902031

BP

regulation of NADP metabolic process

Any process that modulates the frequency, rate or extent of NADP metabolic process.

ME2

GO:1902033

BP

regulation of hematopoietic stem cell proliferation

Any process that modulates the frequency, rate or extent of hematopoietic stem cell proliferation.

ACE

GO:1902035

BP

positive regulation of hematopoietic stem cell proliferation

Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell proliferation.

KITLG, PDCD2, N4BP2L2

GO:1902037

BP

negative regulation of hematopoietic stem cell differentiation

Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic stem cell differentiation.

N4BP2L2

GO:1902038

BP

positive regulation of hematopoietic stem cell differentiation

Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell differentiation.

FOXC1

GO:1902041

BP

regulation of extrinsic apoptotic signaling pathway via death domain receptors

Any process that modulates the frequency, rate or extent of extrinsic apoptotic signaling pathway via death domain receptors.

CFLAR, LGALS3, SP100, FAS, TNFSF10, STX4, FADD, RIPK1, CASP8, TRADD, FEM1B

GO:1902042

BP

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

Any process that stops, prevents or reduces the frequency, rate or extent of extrinsic apoptotic signaling pathway via death domain receptors.

CFLAR, FGA, FGB, FGG, RAF1, SERPINE1, ICAM1, GPX1, HMOX1, HGF, TNFAIP3, FAS, HMGB2, NOS3, BRCA1, TNFSF10, DAPK1, FADD, RIPK1, CASP8, PEA15, TRADD, RFFL, ARHGEF2, TMBIM1

GO:1902043

BP

positive regulation of extrinsic apoptotic signaling pathway via death domain receptors

Any process that activates or increases the frequency, rate or extent of extrinsic apoptotic signaling pathway via death domain receptors.

THBS1, SKIL, MAL, STK4, FADD, PMAIP1, PEA15, SFRP1, FAF1

GO:1902044

BP

regulation of Fas signaling pathway

Any process that modulates the frequency, rate or extent of Fas signaling pathway.

SP100

GO:1902045

BP

negative regulation of Fas signaling pathway

Any process that stops, prevents or reduces the frequency, rate or extent of Fas signaling pathway.

TMBIM1

GO:1902065

BP

response to L-glutamate

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an L-glutamate stimulus.

AIFM1, PCNA, CREB1

GO:1902068

BP

regulation of sphingolipid mediated signaling pathway

Any process that modulates the frequency, rate or extent of sphingolipid signaling.

PLPP3

GO:1902074

BP

response to salt

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salt stimulus.

EDN1, HRSP12

GO:1902081

BP

negative regulation of calcium ion import into sarcoplasmic reticulum

Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion import into sarcoplasmic reticulum.

PLN

GO:1902083

BP

negative regulation of peptidyl-cysteine S-nitrosylation

Any process that stops, prevents or reduces the frequency, rate or extent of peptidyl-cysteine S-nitrosylation.

DMD, ATP2B4, SNTA1

GO:1902098

MF

calcitriol binding

Interacting selectively and non-covalently with calcitriol. Calcitriol (1,25-dihydroxycholecalciferol) is the hormonally active form of vitamin D3.

VDR

GO:1902108

BP

regulation of mitochondrial membrane permeability involved in apoptotic process

Any regulation of mitochondrial membrane permeability that is involved in apoptotic process.

THEM4

GO:1902109

BP

negative regulation of mitochondrial membrane permeability involved in apoptotic process

Any negative regulation of mitochondrial membrane permeability that is involved in apoptotic process.

NOL3

GO:1902115

BP

regulation of organelle assembly

Any process that modulates the frequency, rate or extent of organelle assembly.

EZR, RDX

GO:1902118

MF

calcidiol binding

Interacting selectively and non-covalently with calcidiol.

GC

GO:1902121

MF

lithocholic acid binding

Interacting selectively and non-covalently with lithocholic acid.

VDR

GO:1902122

MF

chenodeoxycholic acid binding

Interacting selectively and non-covalently with chenodeoxycholic acid.

NR1H4

GO:1902161

BP

positive regulation of cyclic nucleotide-gated ion channel activity

Any process that activates or increases the frequency, rate or extent of cyclic nucleotide-gated ion channel activity.

CFTR

GO:1902166

BP

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator.

TRIAP1, KDM1A, CD74, MIF, MUC1, CD44, BCL2L12, TAF9B

GO:1902170

BP

cellular response to reactive nitrogen species

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive nitrogen species stimulus.

MAP3K5

GO:1902172

BP

regulation of keratinocyte apoptotic process

Any process that modulates the frequency, rate or extent of keratinocyte apoptotic process.

ZFP36, ZFP36L1

GO:1902173

BP

negative regulation of keratinocyte apoptotic process

Any process that stops, prevents or reduces the frequency, rate or extent of keratinocyte apoptotic process.

SERPINB13

GO:1902174

BP

positive regulation of keratinocyte apoptotic process

Any process that activates or increases the frequency, rate or extent of keratinocyte apoptotic process.

SFRP4

GO:1902175

BP

regulation of oxidative stress-induced intrinsic apoptotic signaling pathway

Any process that modulates the frequency, rate or extent of an oxidative stress-induced intrinsic apoptotic signaling pathway.

P4HB

GO:1902176

BP

negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway

Any process that stops, prevents or reduces the frequency, rate or extent of an oxidative stress-induced intrinsic apoptotic signaling pathway.

NOL3, VNN1, INS, SOD2, HSPB1, GPX1, AKT1, MAPK7, BAG5

GO:1902177

BP

positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway

Any process that activates or increases the frequency, rate or extent of an oxidative stress-induced intrinsic apoptotic signaling pathway.

SFPQ

GO:1902186

BP

regulation of viral release from host cell

Any process that modulates the frequency, rate or extent of viral release from host cell.

TRIM25, TRIM62

GO:1902187

BP

negative regulation of viral release from host cell

Any process that stops, prevents or reduces the frequency, rate or extent of viral release from host cell.

TRIM13, TRIM26, TRIM28, TRIM25, TRIM8, TRIM35

GO:1902188

BP

positive regulation of viral release from host cell

Any process that activates or increases the frequency, rate or extent of viral release from host cell.

CHMP2A, VPS4B, CHMP4B

GO:1902202

BP

regulation of hepatocyte growth factor receptor signaling pathway

Any process that modulates the frequency, rate or extent of hepatocyte growth factor receptor signaling pathway.

PTPN2

GO:1902203

BP

negative regulation of hepatocyte growth factor receptor signaling pathway

Any process that stops, prevents or reduces the frequency, rate or extent of hepatocyte growth factor receptor signaling pathway.

ADAMTS12

GO:1902204

BP

positive regulation of hepatocyte growth factor receptor signaling pathway

Any process that activates or increases the frequency, rate or extent of hepatocyte growth factor receptor signaling pathway.

ESM1

GO:1902206

BP

negative regulation of interleukin-2-mediated signaling pathway

Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-2-mediated signaling pathway.

PTPN2

GO:1902212

BP

negative regulation of prolactin signaling pathway

Any process that stops, prevents or reduces the frequency, rate or extent of prolactin signaling pathway.

PTPN2

GO:1902213

BP

positive regulation of prolactin signaling pathway

Any process that activates or increases the frequency, rate or extent of prolactin signaling pathway.

CREBRF

GO:1902215

BP

negative regulation of interleukin-4-mediated signaling pathway

Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-4-mediated signaling pathway.

PTPN2

GO:1902219

BP

negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress

Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress.

ARHGEF2

GO:1902227

BP

negative regulation of macrophage colony-stimulating factor signaling pathway

Any process that stops, prevents or reduces the frequency, rate or extent of macrophage colony-stimulating factor signaling pathway.

PTPN2

GO:1902230

BP

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage

Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage.

SNAI2, CLU, TPT1, CXCL12, CCAR2

GO:1902231

BP

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage

Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage.

SKIL, FBXO18, RAD9A

GO:1902233

BP

negative regulation of positive thymic T cell selection

Any process that stops, prevents or reduces the frequency, rate or extent of positive thymic T cell selection.

PTPN2

GO:1902235

BP

regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

Any process that modulates the frequency, rate or extent of an endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway.

ERP29

GO:1902236

BP

negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

Any process that stops, prevents or reduces the frequency, rate or extent of an endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway.

PARK2, OPA1, HSPA1A, HSPA1B, XBP1, GRINA, SYVN1, CREB3L1, VIMP

GO:1902237

BP

positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

Any process that activates or increases the frequency, rate or extent of an endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway.

BCL2L11, PTPN2, DDIT3, SERINC3, PMAIP1

GO:1902254

BP

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator

Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway by p53 class mediator.

PARK2, PTTG1IP, RRN3

GO:1902256

BP

regulation of apoptotic process involved in outflow tract morphogenesis

Any process that modulates the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis.

TGFB2

GO:1902257

BP

negative regulation of apoptotic process involved in outflow tract morphogenesis

Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis.

FOXC1

GO:1902259

BP

regulation of delayed rectifier potassium channel activity

Any process that modulates the frequency, rate or extent of delayed rectifier potassium channel activity.

VAMP2, KCNG1

GO:1902260

BP

negative regulation of delayed rectifier potassium channel activity

Any process that stops, prevents or reduces the frequency, rate or extent of delayed rectifier potassium channel activity.

ANK3

GO:1902261

BP

positive regulation of delayed rectifier potassium channel activity

Any process that activates or increases the frequency, rate or extent of delayed rectifier potassium channel activity.

AKAP6

GO:1902262

BP

apoptotic process involved in patterning of blood vessels

Any apoptotic process that is involved in patterning of blood vessels.

LRP5, BAX

GO:1902263

BP

apoptotic process involved in embryonic digit morphogenesis

Any apoptotic process that is involved in embryonic digit morphogenesis.

BCL2L11, NOTCH1, BAX

GO:1902268

BP

negative regulation of polyamine transmembrane transport

Any process that stops, prevents or reduces the frequency, rate or extent of polyamine transmembrane transport.

OAZ2, OAZ1

GO:1902269

BP

positive regulation of polyamine transmembrane transport

Any process that activates or increases the frequency, rate or extent of polyamine transmembrane transport.

AZIN1

GO:1902275

BP

regulation of chromatin organization

Any process that modulates the frequency, rate or extent of chromatin organization.

MKI67

GO:1902282

MF

voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization

Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of a ventricular cardiomyocyte contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.

KCNH2

GO:1902283

BP

negative regulation of primary amine oxidase activity

Any process that stops, prevents or reduces the frequency, rate or extent of primary amine oxidase activity.

PARK2

GO:1902285

BP

semaphorin-plexin signaling pathway involved in neuron projection guidance

Any semaphorin-plexin signaling pathway that is involved in neuron projection guidance.

NRP1, NRP2, SEMA3A

GO:1902287

BP

semaphorin-plexin signaling pathway involved in axon guidance

Any semaphorin-plexin signaling pathway that is involved in axon guidance.

NRP1, PLXNB2, PLXNC1, PLXNA2, PLXNA3, SEMA3A, PLXNA1, PLXND1

GO:1902303

BP

negative regulation of potassium ion export

Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion export.

KCNH2

GO:1902304

BP

positive regulation of potassium ion export

Any process that activates or increases the frequency, rate or extent of potassium ion export.

ANO6

GO:1902305

BP

regulation of sodium ion transmembrane transport

Any process that modulates the frequency, rate or extent of sodium ion transmembrane transport.

ATP2B4, FGF12, DLG1, SNTA1, RANGRF

GO:1902306

BP

negative regulation of sodium ion transmembrane transport

Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion transmembrane transport.

CAMK2D, COMMD1, NEDD4L

GO:1902307

BP

positive regulation of sodium ion transmembrane transport

Any process that activates or increases the frequency, rate or extent of sodium ion transmembrane transport.

ARF1

GO:1902309

BP

negative regulation of peptidyl-serine dephosphorylation

Any process that stops, prevents or reduces the frequency, rate or extent of peptidyl-serine dephosphorylation.

YWHAE

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