| GO ID | Ontology | GO Term | Term Definition |
Proteins |
GO:1901142 | BP | insulin metabolic process | The chemical reactions and pathways involving insulin. |
ERN1, IDE |
GO:1901143 | BP | insulin catabolic process | The chemical reactions and pathways resulting in the breakdown of insulin. |
IDE |
GO:1901164 | BP | negative regulation of trophoblast cell migration | Any process that stops, prevents or reduces the frequency, rate or extent of trophoblast cell migration. |
TIMP1, ARHGDIB |
GO:1901165 | BP | positive regulation of trophoblast cell migration | Any process that activates or increases the frequency, rate or extent of trophoblast cell migration. |
ACVR1B, C1QBP, SMURF2 |
GO:1901166 | BP | neural crest cell migration involved in autonomic nervous system development | Any neural crest cell migration that is involved in autonomic nervous system development. |
NRP1, SEMA3A |
GO:1901184 | BP | regulation of ERBB signaling pathway | Any process that modulates the frequency, rate or extent of ERBB signaling pathway. |
SH3TC2 |
GO:1901187 | BP | regulation of ephrin receptor signaling pathway | Any process that modulates the frequency, rate or extent of ephrin receptor signaling pathway. |
ANKS1A |
GO:1901194 | BP | negative regulation of formation of translation preinitiation complex | Any process that stops, prevents or reduces the frequency, rate or extent of formation of translation preinitiation complex. |
RPL13A |
GO:1901201 | BP | regulation of extracellular matrix assembly | Any process that modulates the frequency, rate or extent of extracellular matrix assembly. |
AGT, NOTCH1 |
GO:1901203 | BP | positive regulation of extracellular matrix assembly | Any process that activates or increases the frequency, rate or extent of extracellular matrix assembly. |
TGFB1, SOX9, SMAD3, RGCC |
GO:1901205 | BP | negative regulation of adrenergic receptor signaling pathway involved in heart process | Any process that stops, prevents or reduces the frequency, rate or extent of a cardiac adrenergic receptor signaling pathway. |
ATP2B4 |
GO:1901214 | BP | regulation of neuron death | Any process that modulates the frequency, rate or extent of neuron death. |
RAB29, CLU, CCL5, EPHB1, RRAS2, DHCR24, SARM1, CHP1, TBK1 |
GO:1901215 | BP | negative regulation of neuron death | Any process that stops, prevents or reduces the frequency, rate or extent of neuron death. |
PARK2, APOE, IL6, CREB1, AKT1, CTNNB1, SERPINF1, SNCA, STAT3, PSMC1, CDK5, HSF1, REL, PPARA, TMEM259, SORL1, CHMP4B, ATP13A2, PPARGC1A |
GO:1901216 | BP | positive regulation of neuron death | Any process that activates or increases the frequency, rate or extent of neuron death. |
EIF2S1, PARP1, CLU, ELK1, GSK3B, PICALM, TP53BP2, BAD, MAP3K5, DDIT4 |
GO:1901222 | BP | regulation of NIK/NF-kappaB signaling | Any process that modulates the frequency, rate or extent of NIK/NF-kappaB signaling. |
UACA, AKIP1, PTPN22 |
GO:1901223 | BP | negative regulation of NIK/NF-kappaB signaling | Any process that stops, prevents or reduces the frequency, rate or extent of NIK/NF-kappaB signaling. |
TSPAN6, RELA, HDAC7, ADIPOR1 |
GO:1901224 | BP | positive regulation of NIK/NF-kappaB signaling | Any process that activates or increases the frequency, rate or extent of NIK/NF-kappaB signaling. |
ACTN4, TNF, CALR, RC3H2 |
GO:1901253 | BP | negative regulation of intracellular transport of viral material | Any process that stops, prevents or reduces the frequency, rate or extent of intracellular transport of viral material. |
BST2 |
GO:1901254 | BP | positive regulation of intracellular transport of viral material | Any process that activates or increases the frequency, rate or extent of intracellular transport of viral material. |
FMR1 |
GO:1901255 | BP | nucleotide-excision repair involved in interstrand cross-link repair | Any nucleotide-excision repair that is involved in interstrand cross-link repair. |
XPA, ERCC4 |
GO:1901256 | BP | regulation of macrophage colony-stimulating factor production | Any process that modulates the frequency, rate or extent of macrophage colony-stimulating factor production. |
FOXP1 |
GO:1901264 | BP | carbohydrate derivative transport | The directed movement of a carbohydrate derivative into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
SLC35E3 |
GO:1901292 | BP | nucleoside phosphate catabolic process | The chemical reactions and pathways resulting in the breakdown of a nucleoside phosphate. |
NUDT15 |
GO:1901296 | BP | negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment | Any process that stops, prevents or reduces the frequency, rate or extent of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment. |
DKK1 |
GO:1901299 | BP | negative regulation of hydrogen peroxide-mediated programmed cell death | Any process that stops, prevents or reduces the frequency, rate or extent of hydrogen peroxide-mediated programmed cell death. |
MET, HGF |
GO:1901300 | BP | positive regulation of hydrogen peroxide-mediated programmed cell death | Any process that activates or increases the frequency, rate or extent of hydrogen peroxide-mediated programmed cell death. |
FOXO3, PAWR, HDAC6 |
GO:1901303 | BP | negative regulation of cargo loading into COPII-coated vesicle | Any process that stops, prevents or reduces the frequency, rate or extent of cargo loading into a COPII-coated vesicle. |
INSIG1 |
GO:1901315 | BP | negative regulation of histone H2A K63-linked ubiquitination | Any process that stops, prevents or reduces the frequency, rate or extent of histone H2A K63-linked ubiquitination. |
UBR5, OTUB1 |
GO:1901318 | BP | negative regulation of flagellated sperm motility | Any process that stops, prevents or reduces the frequency, rate or extent of flagellated sperm motility. |
RGN |
GO:1901350 | BP | cell-cell signaling involved in cell-cell junction organization | Any cell-cell signaling that is involved in cell-cell junction organization. |
TJP1 |
GO:1901355 | BP | response to rapamycin | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rapamycin stimulus. |
HNRNPD |
GO:1901373 | BP | lipid hydroperoxide transport | The directed movement of a lipid hydroperoxide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
SCP2 |
GO:1901374 | BP | acetate ester transport | The directed movement of an acetate ester into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
SLC22A1 |
GO:1901379 | BP | regulation of potassium ion transmembrane transport | Any process that modulates the frequency, rate or extent of potassium ion transmembrane transport. |
PRNP, DPP6, KCNH2, KCNIP2 |
GO:1901380 | BP | negative regulation of potassium ion transmembrane transport | Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion transmembrane transport. |
CAV1, KCNH2, NEDD4L, CAB39 |
GO:1901381 | BP | positive regulation of potassium ion transmembrane transport | Any process that activates or increases the frequency, rate or extent of potassium ion transmembrane transport. |
KCNH2, AKAP6 |
GO:1901382 | BP | regulation of chorionic trophoblast cell proliferation | Any process that modulates the frequency, rate or extent of chorionic trophoblast cell proliferation. |
BOK |
GO:1901385 | BP | regulation of voltage-gated calcium channel activity | Any process that modulates the frequency, rate or extent of voltage-gated calcium channel activity. |
DMD, CACNB3, AHNAK, STAC |
GO:1901386 | BP | negative regulation of voltage-gated calcium channel activity | Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated calcium channel activity. |
DRD2, OPRL1, FMR1 |
GO:1901387 | BP | positive regulation of voltage-gated calcium channel activity | Any process that activates or increases the frequency, rate or extent of voltage-gated calcium channel activity. |
EHD3 |
GO:1901407 | BP | regulation of phosphorylation of RNA polymerase II C-terminal domain | Any process that modulates the frequency, rate or extent of phosphorylation of RNA polymerase II C-terminal domain. |
BRD4 |
GO:1901409 | BP | positive regulation of phosphorylation of RNA polymerase II C-terminal domain | Any process that activates or increases the frequency, rate or extent of phosphorylation of RNA polymerase II C-terminal domain. |
CCNT1, CCNT2, CCNL2, CCNL1 |
GO:1901475 | BP | pyruvate transmembrane transport | The directed movement of pyruvate across a membrane. |
SLC16A7 |
GO:1901491 | BP | negative regulation of lymphangiogenesis | Any process that stops, prevents or reduces the frequency, rate or extent of lymphangiogenesis. |
FOXC1 |
GO:1901492 | BP | positive regulation of lymphangiogenesis | Any process that activates or increases the frequency, rate or extent of lymphangiogenesis. |
VEGFC, CCBE1 |
GO:1901509 | BP | regulation of endothelial tube morphogenesis | Any process that modulates the frequency, rate or extent of endothelial tube morphogenesis. |
ADAMTS12, FOXP1 |
GO:1901522 | BP | positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus | Any positive regulation of transcription from RNA polymerase II promoter that is involved in cellular response to chemical stimulus. |
SMAD9, BMP2, DLX5, SMAD4, RUNX2, SMAD1, SMAD5 |
GO:1901529 | BP | positive regulation of anion channel activity | Any process that activates or increases the frequency, rate or extent of anion channel activity. |
TCAF1 |
GO:1901532 | BP | regulation of hematopoietic progenitor cell differentiation | Any process that modulates the frequency, rate or extent of hematopoietic progenitor cell differentiation. |
PDCD2 |
GO:1901534 | BP | positive regulation of hematopoietic progenitor cell differentiation | Any process that activates or increases the frequency, rate or extent of hematopoietic progenitor cell differentiation. |
FOXC1 |
GO:1901536 | BP | negative regulation of DNA demethylation | Any process that stops, prevents or reduces the frequency, rate or extent of DNA demethylation. |
TRIM28 |
GO:1901558 | BP | response to metformin | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metformin stimulus. |
PPARG, PPARGC1A |
GO:1901581 | BP | negative regulation of telomeric RNA transcription from RNA pol II promoter | Any process that stops, prevents or reduces the frequency, rate or extent of telomeric RNA transcription from RNA pol II promoter. |
ATRX |
GO:1901582 | BP | positive regulation of telomeric RNA transcription from RNA pol II promoter | Any process that activates or increases the frequency, rate or extent of telomeric RNA transcription from RNA pol II promoter. |
ATRX |
GO:1901585 | BP | regulation of acid-sensing ion channel activity | Any process that modulates the frequency, rate or extent of acid-sensing ion channel activity. |
STOM |
GO:1901594 | BP | response to capsazepine | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a capsazepine stimulus. |
TRPV1 |
GO:1901611 | MF | phosphatidylglycerol binding | Interacting selectively and non-covalently with phosphatidylglycerol. |
PITPNA, PITPNC1 |
GO:1901612 | MF | cardiolipin binding | Interacting selectively and non-covalently with cardiolipin. |
ATP8B1, UQCC3 |
GO:1901620 | BP | regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning | Any process that modulates the frequency, rate or extent of smoothened signaling pathway involved in dorsal/ventral neural tube patterning. |
MKS1 |
GO:1901621 | BP | negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning | Any process that stops, prevents or reduces the frequency, rate or extent of smoothened signaling pathway involved in dorsal/ventral neural tube patterning. |
TULP3, PRKACA, SUFU |
GO:1901628 | BP | positive regulation of postsynaptic membrane organization | Any process that activates or increases the frequency, rate or extent of postsynaptic membrane organization. |
APOE |
GO:1901630 | BP | negative regulation of presynaptic membrane organization | Any process that stops, prevents or reduces the frequency, rate or extent of presynaptic membrane organization. |
APOE |
GO:1901639 | BP | XDP catabolic process | The chemical reactions and pathways resulting in the breakdown of XDP. |
NUDT16 |
GO:1901640 | MF | XTP binding | Interacting selectively and non-covalently with XTP. |
NUDT16 |
GO:1901641 | MF | ITP binding | Interacting selectively and non-covalently with ITP. |
NUDT16 |
GO:1901642 | BP | nucleoside transmembrane transport | The directed movement of nucleoside across a membrane. |
SLC29A1 |
GO:1901652 | BP | response to peptide | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide stimulus. |
AVPR2, OXTR |
GO:1901653 | BP | cellular response to peptide | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide stimulus. |
KLF4, AKR1B1, ID1, KLF3, KLF10, KLF15, KLF2 |
GO:1901657 | BP | glycosyl compound metabolic process | The chemical reactions and pathways involving glycosyl compound. |
LCT, KL |
GO:1901660 | BP | calcium ion export | The directed movement of calcium ion out of a cell or organelle. |
ATP2B1, ATP2B4 |
GO:1901661 | BP | quinone metabolic process | The chemical reactions and pathways involving quinone. |
CRYZL1 |
GO:1901666 | BP | positive regulation of NAD+ ADP-ribosyltransferase activity | Any process that activates or increases the frequency, rate or extent of NAD+ ADP-ribosyltransferase activity. |
TGFB1 |
GO:1901671 | BP | positive regulation of superoxide dismutase activity | Any process that activates or increases the frequency, rate or extent of superoxide dismutase activity. |
TNF, RGN |
GO:1901673 | BP | regulation of mitotic spindle assembly | Any process that modulates the frequency, rate or extent of mitotic spindle assembly. |
CHMP2A, VPS4B, TPR, PLK1, CHMP4B |
GO:1901676 | BP | positive regulation of histone H3-K27 acetylation | Any process that activates or increases the frequency, rate or extent of histone H3-K27 acetylation. |
LIF |
GO:1901687 | BP | glutathione derivative biosynthetic process | The chemical reactions and pathways resulting in the formation of glutathione derivative. |
MGST3, GSTA4, GSTZ1, GSTA1, GSTP1, GSTM1, MGST1, GSTM3, GSTM2, GSTT1, GSTO1, GSTM4, MGST2, GSTO2, GSTK1 |
GO:1901707 | MF | leptomycin B binding | Interacting selectively and non-covalently with leptomycin B. |
ID3 |
GO:1901723 | BP | negative regulation of cell proliferation involved in kidney development | Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation involved in kidney development. |
FLCN |
GO:1901724 | BP | positive regulation of cell proliferation involved in kidney development | Any process that activates or increases the frequency, rate or extent of cell proliferation involved in kidney development. |
LIN28A |
GO:1901725 | BP | regulation of histone deacetylase activity | Any process that modulates the frequency, rate or extent of histone deacetylase activity. |
CAMK2D |
GO:1901726 | BP | negative regulation of histone deacetylase activity | Any process that stops, prevents or reduces the frequency, rate or extent of histone deacetylase activity. |
KDM5A |
GO:1901727 | BP | positive regulation of histone deacetylase activity | Any process that activates or increases the frequency, rate or extent of histone deacetylase activity. |
VEGFA, PRKD1, C6orf89, PINK1, PRKD2 |
GO:1901740 | BP | negative regulation of myoblast fusion | Any process that stops, prevents or reduces the frequency, rate or extent of myoblast fusion. |
CFLAR |
GO:1901741 | BP | positive regulation of myoblast fusion | Any process that activates or increases the frequency, rate or extent of myoblast fusion. |
FLOT1, CD53, IL4R, NFATC2, MAPK14, GDF15 |
GO:1901796 | BP | regulation of signal transduction by p53 class mediator | Any process that modulates the frequency, rate or extent of signal transduction by p53 class mediator. |
CHEK1, AURKA, MDM4, NUAK1, RAD1, NBN, MBD3, TP53, UBC, CDK2, AKT1, RPA3, RFC4, RFC2, BRCA1, RFC5, RFC3, MRE11A, DNA2, BLM, PRKAG1, PRKAA2, RPS27A, UBA52, CDK5, MDM2, SSRP1, RBBP4, EP300, TAF10, HDAC1, TP53BP2, CHD4, TAF5, TAF11, STK11, TAF12, MAPK14, RAD9B, JMY, BANP, SETD9, PPP1R13L, ATRIP, TOPBP1, DYRK2, HDAC2, KAT6A, RAD50, TP53INP1, AURKB, EHMT2, TP53RK, RAD9A, BARD1, RHNO1, PHF20, HIPK2, MEAF6, TAF9B, BRD7, KMT5A, PRKAG3, TPX2, EXO1, NOC2L, L3MBTL1, SUPT16H |
GO:1901797 | BP | negative regulation of signal transduction by p53 class mediator | Any process that stops, prevents or reduces the frequency, rate or extent of signal transduction by p53 class mediator. |
MDM2, RFFL |
GO:1901798 | BP | positive regulation of signal transduction by p53 class mediator | Any process that activates or increases the frequency, rate or extent of signal transduction by p53 class mediator. |
HEXIM1 |
GO:1901799 | BP | negative regulation of proteasomal protein catabolic process | Any process that stops, prevents or reduces the frequency, rate or extent of proteasomal protein catabolic process. |
GABARAPL2, LAMP3 |
GO:1901800 | BP | positive regulation of proteasomal protein catabolic process | Any process that activates or increases the frequency, rate or extent of proteasomal protein catabolic process. |
PARK2, XBP1, PSMC3, PSMC2, PSMC4, PSMC1, PSMC6, FMR1 |
GO:1901835 | BP | positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA | Any process that activates or increases the frequency, rate or extent of deadenylation-independent decapping of nuclear-transcribed mRNA. |
ZFP36 |
GO:1901837 | BP | negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter | Any process that stops, prevents or reduces the frequency, rate or extent of transcription of nuclear large rRNA transcript from RNA polymerase I promoter. |
H2AFY, H2AFY2 |
GO:1901838 | BP | positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter | Any process that activates or increases the frequency, rate or extent of transcription of nuclear large rRNA transcript from RNA polymerase I promoter. |
SMARCA4, NOL11 |
GO:1901841 | BP | regulation of high voltage-gated calcium channel activity | Any process that modulates the frequency, rate or extent of high voltage-gated calcium channel activity. |
SRI, CALM2 |
GO:1901843 | BP | positive regulation of high voltage-gated calcium channel activity | Any process that activates or increases the frequency, rate or extent of high voltage-gated calcium channel activity. |
CACNA2D1, FGF14 |
GO:1901844 | BP | regulation of cell communication by electrical coupling involved in cardiac conduction | Any process that modulates the frequency, rate or extent of cell communication by electrical coupling involved in cardiac conduction. |
SRI, CALM2, CAV1, PDE4D, CAMK2D |
GO:1901856 | BP | negative regulation of cellular respiration | Any process that stops, prevents or reduces the frequency, rate or extent of cellular respiration. |
FLCN |
GO:1901857 | BP | positive regulation of cellular respiration | Any process that activates or increases the frequency, rate or extent of cellular respiration. |
PPARGC1A, PRELID1 |
GO:1901859 | BP | negative regulation of mitochondrial DNA metabolic process | Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial DNA metabolic process. |
FLCN |
GO:1901860 | BP | positive regulation of mitochondrial DNA metabolic process | Any process that activates or increases the frequency, rate or extent of mitochondrial DNA metabolic process. |
PPARGC1A |
GO:1901862 | BP | negative regulation of muscle tissue development | Any process that stops, prevents or reduces the frequency, rate or extent of muscle tissue development. |
IGFBP5, FLCN |