| GO ID | Ontology | GO Term | Term Definition |
Proteins |
GO:1900042 | BP | positive regulation of interleukin-2 secretion | Any process that activates or increases the frequency, rate or extent of interleukin-2 secretion. |
SPTBN1, CD276, VTCN1 |
GO:1900053 | BP | negative regulation of retinoic acid biosynthetic process | Any process that stops, prevents or reduces the frequency, rate or extent of retinoic acid biosynthetic process. |
AKR1C3 |
GO:1900060 | BP | negative regulation of ceramide biosynthetic process | Any process that stops, prevents or reduces the frequency, rate or extent of a ceramide biosynthetic process. |
ORMDL2 |
GO:1900062 | BP | regulation of replicative cell aging | Any process that modulates the frequency, rate or extent of replicative cell aging. |
NEK4 |
GO:1900063 | BP | regulation of peroxisome organization | Any process that modulates the frequency, rate or extent of peroxisome organization. |
MAVS, MFF |
GO:1900076 | BP | regulation of cellular response to insulin stimulus | Any process that modulates the frequency, rate or extent of cellular response to insulin stimulus. |
GPLD1 |
GO:1900078 | BP | positive regulation of cellular response to insulin stimulus | Any process that activates or increases the frequency, rate or extent of cellular response to insulin stimulus. |
MYO1C, ESRRA |
GO:1900082 | BP | negative regulation of arginine catabolic process | Any process that stops, prevents or reduces the frequency, rate or extent of arginine catabolic process. |
ATP2B4 |
GO:1900085 | BP | negative regulation of peptidyl-tyrosine autophosphorylation | Any process that stops, prevents or reduces the frequency, rate or extent of peptidyl-tyrosine autophosphorylation. |
CAV1 |
GO:1900086 | BP | positive regulation of peptidyl-tyrosine autophosphorylation | Any process that activates or increases the frequency, rate or extent of peptidyl-tyrosine autophosphorylation. |
GREM1, ACE, VEGFA, IQGAP1 |
GO:1900087 | BP | positive regulation of G1/S transition of mitotic cell cycle | Any cell cycle regulatory process that promotes the commitment of a cell from G1 to S phase of the mitotic cell cycle. |
DDX3X, PLRG1, ANXA1, CYP1A1, CCND2, RDX, CUL4A, CUL4B, UBE2E2, PLCB1 |
GO:1900095 | BP | regulation of dosage compensation by inactivation of X chromosome | Any process that modulates the frequency, rate or extent of dosage compensation, by inactivation of X chromosome. |
RLIM |
GO:1900100 | BP | positive regulation of plasma cell differentiation | Any process that activates or increases the frequency, rate or extent of plasma cell differentiation. |
XBP1 |
GO:1900102 | BP | negative regulation of endoplasmic reticulum unfolded protein response | Any process that stops, prevents or reduces the frequency, rate or extent of endoplasmic reticulum unfolded protein response. |
RACK1 |
GO:1900103 | BP | positive regulation of endoplasmic reticulum unfolded protein response | Any process that activates or increases the frequency, rate or extent of endoplasmic reticulum unfolded protein response. |
ERN1, XBP1, PIK3R1, BAX |
GO:1900112 | BP | regulation of histone H3-K9 trimethylation | Any process that modulates the frequency, rate or extent of histone H3-K9 trimethylation. |
ATRX, ZNF274 |
GO:1900116 | BP | extracellular negative regulation of signal transduction | Any negative regulation of signal transduction that takes place in extracellular region. |
DKK1, LRPAP1, ADH7, AGTR2, ESR2 |
GO:1900118 | BP | negative regulation of execution phase of apoptosis | Any process that stops, prevents or reduces the frequency, rate or extent of execution phase of apoptosis. |
DFFA, GCG |
GO:1900119 | BP | positive regulation of execution phase of apoptosis | Any process that activates or increases the frequency, rate or extent of execution phase of apoptosis. |
TP53, TP53BP2, PTGIS, SIRT2, DLC1, BOK |
GO:1900121 | BP | negative regulation of receptor binding | Any process that stops, prevents or reduces the frequency, rate or extent of a protein or other molecule binding to a receptor. |
ANXA2, PTPRF, B2M, ADIPOQ, HFE, CRTAC1 |
GO:1900122 | BP | positive regulation of receptor binding | Any process that activates or increases the frequency, rate or extent of a protein or other molecule binding to a receptor. |
MMP9, B2M, PLCL1, HFE, PLCL2 |
GO:1900126 | BP | negative regulation of hyaluronan biosynthetic process | Any process that stops, prevents or reduces the frequency, rate or extent of hyaluronan biosynthetic process. |
TGFB1 |
GO:1900127 | BP | positive regulation of hyaluronan biosynthetic process | Any process that activates or increases the frequency, rate or extent of hyaluronan biosynthetic process. |
PDGFB, NFKB1, HAS2 |
GO:1900133 | BP | regulation of renin secretion into blood stream | Any process that modulates the frequency, rate or extent of renin secretion into blood stream. |
GJA5 |
GO:1900134 | BP | negative regulation of renin secretion into blood stream | Any process that stops, prevents or reduces the frequency, rate or extent of renin secretion into blood stream. |
F2R |
GO:1900135 | BP | positive regulation of renin secretion into blood stream | Any process that activates or increases the frequency, rate or extent of renin secretion into blood stream. |
F2RL1, OR51E2 |
GO:1900138 | BP | negative regulation of phospholipase A2 activity | Any process that stops, prevents or reduces the frequency, rate or extent of phospholipase A2 activity. |
ANXA1 |
GO:1900142 | BP | negative regulation of oligodendrocyte apoptotic process | Any process that stops, prevents or reduces the frequency, rate or extent of oligodendrocyte apoptotic process. |
GAS6 |
GO:1900153 | BP | positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay | Any process that activates or increases the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay. |
CNOT1, ZFP36, ZFP36L2, ZFP36L1, CPEB3, NANOS1, TNRC6C, CNOT7, AGO2, TNRC6B |
GO:1900155 | BP | negative regulation of bone trabecula formation | Any process that stops, prevents or reduces the frequency, rate or extent of bone trabecula formation. |
GREM1 |
GO:1900158 | BP | negative regulation of bone mineralization involved in bone maturation | Any process that stops, prevents or reduces the frequency, rate or extent of bone mineralization involved in bone maturation. |
GREM1, FAM101A, FAM101B |
GO:1900163 | BP | positive regulation of phospholipid scramblase activity | Any process that activates or increases the frequency, rate or extent of phospholipid scramblase activity. |
PRKCD |
GO:1900164 | BP | nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry | A series of molecular signals initiated by the binding of a nodal protein to an activin receptor on the surface of a target cell, which contributes to the establishment of lateral mesoderm with respect to the left and right halves. |
CITED2 |
GO:1900165 | BP | negative regulation of interleukin-6 secretion | Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-6 secretion. |
GAS6, SYT11, C1QTNF3, RABGEF1, PTPN22 |
GO:1900168 | BP | positive regulation of glial cell-derived neurotrophic factor secretion | Any process that activates or increases the frequency, rate or extent of glial cell-derived neurotrophic factor secretion. |
DRD2 |
GO:1900169 | BP | regulation of glucocorticoid mediated signaling pathway | Any process that modulates the frequency, rate or extent of glucocorticoid mediated signaling pathway. |
AKAP13 |
GO:1900170 | BP | negative regulation of glucocorticoid mediated signaling pathway | Any process that stops, prevents or reduces the frequency, rate or extent of glucocorticoid mediated signaling pathway. |
CREBRF |
GO:1900180 | BP | regulation of protein localization to nucleus | Any process that modulates the frequency, rate or extent of protein localization to nucleus. |
LMNA, NF2, RASSF5 |
GO:1900181 | BP | negative regulation of protein localization to nucleus | Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to nucleus. |
DCLK1, GSK3B, OTUD7B, FLCN |
GO:1900182 | BP | positive regulation of protein localization to nucleus | Any process that activates or increases the frequency, rate or extent of protein localization to nucleus. |
F2, INS, FYN, CDK1, NGFR, LIF, AKT1, PLK1, SESN2, TGFB2, STK11, TRIM8, GTSE1 |
GO:1900186 | BP | negative regulation of clathrin-dependent endocytosis | Any process that stops, prevents or reduces the frequency, rate or extent of clathrin-mediated endocytosis. |
UNC119 |
GO:1900194 | BP | negative regulation of oocyte maturation | Any process that stops, prevents or reduces the frequency, rate or extent of oocyte maturation. |
NPR2, SHB |
GO:1900195 | BP | positive regulation of oocyte maturation | Any process that activates or increases the frequency, rate or extent of oocyte maturation. |
AURKA, SIRT2 |
GO:1900212 | BP | negative regulation of mesenchymal cell apoptotic process involved in metanephros development | Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell apoptotic process involved in metanephros development. |
PAX8 |
GO:1900215 | BP | negative regulation of apoptotic process involved in metanephric collecting duct development | Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in metanephric collecting duct development. |
PAX8 |
GO:1900218 | BP | negative regulation of apoptotic process involved in metanephric nephron tubule development | Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in metanephric nephron tubule development. |
PAX8 |
GO:1900221 | BP | regulation of beta-amyloid clearance | Any process that modulates the frequency, rate or extent of beta-amyloid clearance. |
APOE, CLU |
GO:1900222 | BP | negative regulation of beta-amyloid clearance | Any process that stops, prevents or reduces the frequency, rate or extent of beta-amyloid clearance. |
LRPAP1 |
GO:1900224 | BP | positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry | Any process that activates or increases the frequency, rate or extent of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry. |
SMAD2 |
GO:1900226 | BP | negative regulation of NLRP3 inflammasome complex assembly | Any process that stops, prevents or reduces the frequency, rate or extent of NLRP3 inflammasome complex assembly. |
SIRT2 |
GO:1900227 | BP | positive regulation of NLRP3 inflammasome complex assembly | Any process that activates or increases the frequency, rate or extent of NLRP3 inflammasome complex assembly. |
TLR4, CD36 |
GO:1900235 | BP | negative regulation of Kit signaling pathway | Any process that stops, prevents or reduces the frequency, rate or extent of Kit signaling pathway. |
RABGEF1 |
GO:1900242 | BP | regulation of synaptic vesicle endocytosis | Any process that modulates the frequency, rate or extent of synaptic vesicle endocytosis. |
BTBD9 |
GO:1900243 | BP | negative regulation of synaptic vesicle endocytosis | Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle endocytosis. |
SYT11 |
GO:1900244 | BP | positive regulation of synaptic vesicle endocytosis | Any process that activates or increases the frequency, rate or extent of synaptic vesicle endocytosis. |
TOR1A, NLGN1 |
GO:1900246 | BP | positive regulation of RIG-I signaling pathway | Any process that activates or increases the frequency, rate or extent of RIG-I signaling pathway. |
PUM1, PUM2 |
GO:1900248 | BP | negative regulation of cytoplasmic translational elongation | Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translational elongation. |
CPEB2, CPEB3 |
GO:1900260 | BP | negative regulation of RNA-directed RNA polymerase activity | Any process that stops, prevents or reduces the frequency, rate or extent of RNA-directed RNA polymerase activity. |
EIF4A2 |
GO:1900264 | BP | positive regulation of DNA-directed DNA polymerase activity | Any process that activates or increases the frequency, rate or extent of DNA-directed DNA polymerase activity. |
RFC4, RFC2, RFC5, RFC3, CHTF18, DSCC1 |
GO:1900271 | BP | regulation of long-term synaptic potentiation | Any process that modulates the frequency, rate or extent of long-term synaptic potentiation. |
PAIP2 |
GO:1900273 | BP | positive regulation of long-term synaptic potentiation | Any process that activates or increases the frequency, rate or extent of long-term synaptic potentiation. |
STAU1, DRD2, CREB1, GRIN2A, EIF2AK4 |
GO:1900275 | BP | negative regulation of phospholipase C activity | Any process that stops, prevents or reduces the frequency, rate or extent of phospholipase C activity. |
BICD1 |
GO:1900276 | BP | regulation of proteinase activated receptor activity | Any process that modulates the frequency, rate or extent of proteinase activated receptor activity. |
BICD1 |
GO:1900281 | BP | positive regulation of CD4-positive, alpha-beta T cell costimulation | Any process that activates or increases the frequency, rate or extent of CD4-positive, alpha-beta T cell costimulation. |
TNFSF4 |
GO:1900363 | BP | regulation of mRNA polyadenylation | Any process that modulates the frequency, rate or extent of mRNA polyadenylation. |
SNRPA |
GO:1900364 | BP | negative regulation of mRNA polyadenylation | Any process that stops, prevents or reduces the frequency, rate or extent of mRNA polyadenylation. |
SUPT5H, CCNT1, ZC3H14 |
GO:1900365 | BP | positive regulation of mRNA polyadenylation | Any process that activates or increases the frequency, rate or extent of mRNA polyadenylation. |
CPEB3 |
GO:1900387 | BP | negative regulation of cell-cell adhesion by negative regulation of transcription from RNA polymerase II promoter | A negative regulation of transcription from RNA polymerase II promoter that results in negative regulation of cell-cell adhesion. |
SNAI2 |
GO:1900407 | BP | regulation of cellular response to oxidative stress | Any process that modulates the frequency, rate or extent of cellular response to oxidative stress. |
PARK2, PINK1, FUT8 |
GO:1900424 | BP | regulation of defense response to bacterium | Any process that modulates the frequency, rate or extent of defense response to bacterium. |
SYT11, FOXP1 |
GO:1900425 | BP | negative regulation of defense response to bacterium | Any process that stops, prevents or reduces the frequency, rate or extent of defense response to bacterium. |
SIRT2 |
GO:1900453 | BP | negative regulation of long term synaptic depression | Any process that stops, prevents or reduces the frequency, rate or extent of long term synaptic depression. |
ADORA1, FMR1 |
GO:1900483 | BP | regulation of protein targeting to vacuolar membrane | Any process that modulates the frequency, rate or extent of protein targeting to vacuolar membrane. |
VAMP7 |
GO:1900535 | BP | palmitic acid biosynthetic process | The chemical reactions and pathways resulting in the formation of palmitic acid. |
ACOT7 |
GO:1900625 | BP | positive regulation of monocyte aggregation | Any process that activates or increases the frequency, rate or extent of monocyte aggregation. |
CD44, NR4A3, HAS2 |
GO:1900737 | BP | negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway | Any process that stops, prevents or reduces the frequency, rate or extent of phospholipase C-activating G-protein coupled receptor signaling pathway. |
BICD1 |
GO:1900738 | BP | positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway | Any process that activates or increases the frequency, rate or extent of phospholipase C-activating G-protein coupled receptor signaling pathway. |
F2, GPR27 |
GO:1900740 | BP | positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway | Any process that activates or increases the frequency, rate or extent of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway. |
BCL2L11, TP53, BCL2, YWHAB, SFN, MAPK8, BID, YWHAE, YWHAZ, DYNLL1, E2F1, YWHAH, TP53BP2, PMAIP1, TFDP1, CASP8, BAD |
GO:1900744 | BP | regulation of p38MAPK cascade | Any process that modulates the frequency, rate or extent of p38MAPK cascade. |
PER1, HGF, ULK4 |
GO:1900745 | BP | positive regulation of p38MAPK cascade | Any process that activates or increases the frequency, rate or extent of p38MAPK cascade. |
GADD45B, GADD45G, BMP2, VEGFA, GADD45A, LEP, XDH, MAP3K5, PRMT1, MAP3K4 |
GO:1900747 | BP | negative regulation of vascular endothelial growth factor signaling pathway | Any process that stops, prevents or reduces the frequency, rate or extent of vascular endothelial growth factor signaling pathway. |
DCN, XDH |
GO:1900748 | BP | positive regulation of vascular endothelial growth factor signaling pathway | Any process that activates or increases the frequency, rate or extent of vascular endothelial growth factor signaling pathway. |
MYO1C, CCBE1 |
GO:1900825 | BP | regulation of membrane depolarization during cardiac muscle cell action potential | Any process that modulates the frequency, rate or extent of membrane depolarization during a cardiac muscle cell action potential. |
GJA5, RANGRF |
GO:1900827 | BP | positive regulation of membrane depolarization during cardiac muscle cell action potential | Any process that activates or increases the frequency, rate or extent of membrane depolarization during a cardiac muscle cell action potential. |
ANK3 |
GO:1901003 | BP | negative regulation of fermentation | Any process that stops, prevents or reduces the frequency, rate or extent of fermentation. |
PRKCDBP |
GO:1901016 | BP | regulation of potassium ion transmembrane transporter activity | Any process that modulates the frequency, rate or extent of potassium ion transmembrane transporter activity. |
WWP2, YWHAE, FHL1, NEDD4L |
GO:1901017 | BP | negative regulation of potassium ion transmembrane transporter activity | Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion transmembrane transporter activity. |
ACTN2, NEDD4L, CAB39 |
GO:1901018 | BP | positive regulation of potassium ion transmembrane transporter activity | Any process that activates or increases the frequency, rate or extent of potassium ion transmembrane transporter activity. |
ATP1B1, ACTN2, ATP1B3, ANK2 |
GO:1901019 | BP | regulation of calcium ion transmembrane transporter activity | Any process that modulates the frequency, rate or extent of calcium ion transmembrane transporter activity. |
ANK2 |
GO:1901020 | BP | negative regulation of calcium ion transmembrane transporter activity | Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion transmembrane transporter activity. |
PLN |
GO:1901021 | BP | positive regulation of calcium ion transmembrane transporter activity | Any process that activates or increases the frequency, rate or extent of calcium ion transmembrane transporter activity. |
ANK2 |
GO:1901026 | BP | ripoptosome assembly involved in necroptotic process | The aggregation, arrangement and bonding together of ripoptosome components leading to a necroptotic process. |
RIPK1, SIRT2 |
GO:1901029 | BP | negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway | Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway. |
SLC25A5, HSPA1A, HSPA1B |
GO:1901030 | BP | positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway | Any process that activates or increases the frequency, rate or extent of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway. |
ZNF205, GSK3B, BID, BAX |
GO:1901031 | BP | regulation of response to reactive oxygen species | Any process that modulates the frequency, rate or extent of response to reactive oxygen species. |
SESN2, SESN3, SESN1 |
GO:1901074 | BP | regulation of engulfment of apoptotic cell | Any process that modulates the frequency, rate or extent of engulfment of apoptotic cell. |
ALOX15 |
GO:1901077 | BP | regulation of relaxation of muscle | Any process that modulates the frequency, rate or extent of relaxation of muscle. |
SRI |
GO:1901094 | BP | negative regulation of protein homotetramerization | Any process that stops, prevents or reduces the frequency, rate or extent of protein homotetramerization. |
PEX14 |
GO:1901097 | BP | negative regulation of autophagosome maturation | Any process that stops, prevents or reduces the frequency, rate or extent of autophagosome maturation. |
UBQLN4 |
GO:1901098 | BP | positive regulation of autophagosome maturation | Any process that activates or increases the frequency, rate or extent of autophagosome maturation. |
ADRB2, CALCOCO2 |