GO:0098519

MF

nucleotide phosphatase activity, acting on free nucleotides

Catalysis of the reaction: nucleotide + H2O = nucleotide + phosphate.

DUSP11, NUDT16

GO:0098531

MF

transcription factor activity, direct ligand regulated sequence-specific DNA binding

A DNA binding transcription factor activity that is directly regulated by binding of a ligand to the protein with this activity. Examples include the lac and trp repressors in E.coli and many steroid hormone receptors.

RORA

GO:0098532

BP

histone H3-K27 trimethylation

The modification of histone H3 by addition of three methyl groups to lysine at position 27 of the histone.

HIST1H1E, HIST1H1C, EZH2

GO:0098535

BP

de novo centriole assembly

Centriole assembly in which a centriole arises de novo by a process involving an electron dense structure known as a deuterosome, rather than by duplication of an existing centriole.

PLK4, CEP152

GO:0098536

CC

deuterosome

A spherical, electron dense, cytoplasmic structure that is involved in de novo assembly of centrioles.

PLK4, CEP152

GO:0098547

CC

lumenal side of Golgi membrane

The side of the Golgi membrane that faces the lumen.

NUCB1

GO:0098554

CC

cytoplasmic side of endoplasmic reticulum membrane

The side (leaflet) of the plasma membrane that faces the cytoplasm.

DNAJA1

GO:0098556

CC

cytoplasmic side of rough endoplasmic reticulum membrane

The side (leaflet) of the rough endoplasmic reticulum membrane that faces the cytoplasm.

GNRH1

GO:0098559

CC

cytoplasmic side of early endosome membrane

The side (leaflet) of the early endosome membrane that faces the cytoplasm.

RAB5A, RAB21

GO:0098574

CC

cytoplasmic side of lysosomal membrane

The side (leaflet) of the lysosomal membrane that faces the cytoplasm.

EEF1A1, EEF1A2, LOH12CR1

GO:0098586

BP

cellular response to virus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a virus.

PENK, IL12A, FMR1, MAPK14, TRIM6

GO:0098592

CC

cytoplasmic side of apical plasma membrane

The side (leaflet) of the apical region of the plasma membrane that faces the cytoplasm.

EZR, EXOC1

GO:0098599

MF

palmitoyl hydrolase activity

Catalysis of a hydrolase reaction that removes a palmitoyl moiety from some substrate.

PPT2

GO:0098609

BP

cell-cell adhesion

The attachment of one cell to another cell via adhesion molecules.

ESYT2, PDLIM1, SDCBP, NOP56, DDX3X, CCS, PPL, EXOC3, FLNB, IDH1, RSL1D1, CCNB2, VAPB, LYPLA2, LDHA, ALDOA, KRT18, ENO1, ANXA2, PFN1, SLC3A2, HSP90AB1, HSPA1A, HSPA1B, HSPA5, EEF2, PKM, RPS2, EPCAM, CAST, PCMT1, PAICS, DNAJB1, S100P, EEF1D, PRDX6, YWHAB, SFN, S100A11, RDX, BSG, TAGLN2, CAPG, EIF2S3, TMPO, TMPO, EPS15, RANBP1, RANGAP1, CRKL, IQGAP1, CAPZB, RPL29, CSNK1D, RPL34, FASN, NUMB, MRE11A, EMD, RPL14, CCT8, CAPZA1, ARFIP1, IST1, RARS, EIF5, RPL15, YWHAE, RPL7A, RPL23A, RAB1A, RPS26, YWHAZ, RACK1, HIST1H3D, RPL24, HDLBP, SPTBN1, CALD1, PRDX1, TJP1, GOLGA2, AHNAK, TWF1, PAK2, PICALM, SNX1, CKAP5, CTTN, TRIM25, SEPT2, STK38, PCBP1, CNN3, MAPRE1, RAB11B, SEPT7, PKN2, DBN1, FSCN1, LRRFIP1, COBLL1, FNBP1L, ARHGEF16, TWF2, LARP1, MPRIP, GIGYF2, BZW1, DHX29, PHLDB2, KTN1, ERC1, ABI1, ARHGAP18, SERBP1, GPRC5A, STXBP6, KIAA1524, ZC3H15, PPP1R13L, ATXN2L, H1FX, NDRG1, GCN1, EFHD2, PERP, PDLIM5, SCYL1, FMNL2, FAM129B, TMEM47, CORO1B, EHD4, CHMP4B, EPB41L1, ADGRL3, RTN4, ANLN, DIAPH3, ARGLU1, FLRT3, VAPA, TJP2, TES, LIMA1, BAIAP2L1, PUF60, ASAP1, MKL2, MYO6, MACF1, RUVBL1, SH3GLB1, PPME1, MMP24, SNX9, SNX5, F11R, STK24, BZW2, WASF2

GO:0098619

MF

selenocysteine-tRNA ligase activity

Catalysis of the reaction: tRNASec + L-Ser + ATP ---> Ser-tRNASec + AMP + Diphosphate.

SARS

GO:0098621

MF

phosphoseryl-selenocysteinyl-tRNA selenium transferase activity

Catalysis of the reaction: O-Phosphoseryl-tRNA(Sec) + Selenophosphoric acid + H2O => L-Selenocysteinyl-tRNA(Sec) + 2 phosphoric acid.

SEPSECS

GO:0098625

MF

methylselenol reductase activity

Catalysis of the reaction: NADPH + H+ + CH3SeOH => NADP+ + CH3SeH + H2O

TXNRD1

GO:0098626

MF

methylseleninic acid reductase activity

Catalysis of the reaction: NADPH + H+ + CH3SeO2H => NADP+ + CH3SeOH + H2O.

TXNRD1

GO:0098636

CC

protein complex involved in cell adhesion

Any protein complex that is capable of carrying out some part of the process of cell-cell adhesion.

CD28

GO:0098639

MF

collagen binding involved in cell-matrix adhesion

Any collagen binding that occurs as part of cell-matrix adhesion.

ITGA10, ITGB1, ITGA2, ITGA11

GO:0098641

MF

cadherin binding involved in cell-cell adhesion

Any cadherin binding that occurs as part of the process of cell-cell adhesion.

ESYT2, PDLIM1, CLIC1, SDCBP, NOP56, DDX3X, CCS, PPL, EXOC3, CTNND1, FLNB, IDH1, RSL1D1, CCNB2, VAPB, LYPLA2, LDHA, EGFR, ALDOA, ANXA1, ITGB1, KRT18, ENO1, ANXA2, PFN1, SLC3A2, HSP90AB1, HSPA1A, HSPA1B, HSPA5, EEF2, PKM, JUP, EZR, RPS2, EPCAM, CAST, FLNA, PCMT1, PAICS, ITGA6, DNAJB1, S100P, CTNNA2, EEF1D, PRDX6, YWHAB, SFN, S100A11, CTNNA1, CTNNB1, RDX, MYH9, BSG, TAGLN2, CAPG, EIF2S3, TMPO, TMPO, EPS15, RANBP1, RANGAP1, CRKL, IQGAP1, CAPZB, RPL29, CSNK1D, RPL34, FASN, NUMB, MRE11A, EMD, RPL14, CCT8, CAPZA1, ARFIP1, IST1, RARS, EIF5, RPL15, YWHAE, RPL7A, RPL23A, RAB1A, RPS26, YWHAZ, RACK1, HIST1H3D, RPL24, HDLBP, SPTBN1, CALD1, PRDX1, TJP1, GOLGA2, AHNAK, TWF1, DLG1, PAK2, PICALM, SNX1, CKAP5, CTTN, TRIM25, SEPT2, STK38, PCBP1, CNN3, MAPRE1, RAB11B, SEPT7, PKN2, DBN1, FSCN1, LRRFIP1, COBLL1, FNBP1L, ARHGEF16, TWF2, LARP1, MPRIP, GIGYF2, BZW1, DHX29, PHLDB2, KTN1, ERC1, ABI1, ARHGAP18, SERBP1, GPRC5A, STXBP6, KIAA1524, ZC3H15, PPP1R13L, ATXN2L, H1FX, NDRG1, GCN1, EFHD2, PDLIM5, SCYL1, FMNL2, FAM129B, PKP2, CORO1B, EHD4, CHMP4B, EPB41L1, RTN4, ANLN, DIAPH3, PARVA, ARGLU1, VAPA, TJP2, TES, LIMA1, BAIAP2L1, PUF60, ASAP1, MKL2, MYO6, MACF1, RUVBL1, SH3GLB1, PKP3, TLN1, PPME1, SNX9, SNX5, F11R, STK24, BZW2, WASF2

GO:0098655

BP

cation transmembrane transport

A process in which a cation is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.

SLC22A5, CHRNB1, CHRNA5, CHRNA7, ATP13A5, FAM26F, SLC30A9, PIEZO1, SLC41A3, SLC41A2, P2RX4, ATP13A3, CALHM2, ATP13A2, GAR1

GO:0098656

BP

anion transmembrane transport

A process in which an anion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.

ABCC4, ABCC5, ABCA1, ABCC1, SLC4A8, ABCC10, LRRC8B, LRRC8A, LRRC8C, SLC5A5, SLC4A4

GO:0098700

BP

neurotransmitter loading into synaptic vesicle

The active transport of neurotransmitters into a synaptic vesicle. This import is fuelled by an electrochemical gradient across the vesicle membrane, established by the action proton pumps.

SLC18A2

GO:0098703

BP

calcium ion import across plasma membrane

The directed movement of calcium ions from outside of a cell, across the plasma membrane and into the cytosol.

ATP2B4

GO:0098719

BP

sodium ion import across plasma membrane

The directed movement of sodium ions from outside of a cell, across the plasma membrane and into the cytosol.

SLC9A6, SLC9A2

GO:0098734

BP

macromolecule depalmitoylation

The removal of palymitoyl groups from a macromolecule.

PPT2

GO:0098735

BP

positive regulation of the force of heart contraction

Any process that increases the force of heart muscle contraction.

RYR2

GO:0098736

BP

negative regulation of the force of heart contraction

Any process that decreases the force of heart muscle contraction.

ATP2B4

GO:0098745

CC

Dcp1-Dcp2 complex

A protein complex consisting of a Dcp1 regulatory subunit and a Dcp2 catalytic subunit that has mRNA cap binding activity and is involved in decapping of nuclear-transcribed mRNA.

ZFP36

GO:0098746

BP

fast, calcium ion-dependent exocytosis of neurotransmitter

The fast, initial phase of calcium ion-induced neurotransmitter release, via exocytosis, into the synaptic cleft. This depends on low affinity calcium sensors and typically begins a fraction of a millisecond after Ca2+ influx, and decays rapidly (1-10ms) with a decay constant of around 5-10ms. The underlying molecular mechanisms of this process are distinct from those of the later, slow phase of release.

SYT1

GO:0098749

BP

cerebellar neuron development

The process whose specific outcome is the progression of a cerebellar neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.

NANOS1

GO:0098759

BP

cellular response to interleukin-8

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-8 stimulus.

EGR1

GO:0098770

MF

FBXO family protein binding

Interacting selectively and non-covalently with any member of the FBXO protein family. Members of this family have an F-box protein motif of approximately 50 amino acids that functions as a site of protein-protein interaction.

CDK6

GO:0098772

MF

molecular function regulator

A molecular function that modulates the activity of a gene product or complex. Examples include enzyme regulators and channel regulators.

SEC14L1

GO:0098779

BP

mitophagy in response to mitochondrial depolarization

The macromitophagy process that is triggered by a detection of the loss of mitochondrial membrane potential.

PARK2, ATG13, SQSTM1, CDC37, PINK1, TOMM7, HDAC6

GO:0098789

BP

pre-mRNA cleavage required for polyadenylation

The targeted, endonucleolytic cleavage of a pre-mRNA, required for polyadenylation of the 3' end. This cleavage is directed by binding sites near the 3' end of the mRNA and leaves a 3' hydoxyl end which then becomes a target for adenylation.

NCBP1, CPSF1

GO:0098792

BP

xenophagy

The macroautophagy process in which a region of cytoplasm containing an intracellular pathogen or some part of an intracellular pathogen (e.g. viral capsid) is enclosed in a double membrane bound autophagosome, which then fuses with the lysosome leading to degradation of the contents.

LGALS8, CALCOCO2, OPTN

GO:0098793

CC

presynapse

The part of a synapse that is part of the presynaptic cell.

SNAP23, SYNJ1, PARK2, PIP5K1C, SNAP29, PSEN1, CDK5, FMR1, EEA1, PDZD11, NLGN1, SYTL5, SYTL4, SYT11, LIN7B, LIN7C, BLOC1S6, HRH3

GO:0098794

CC

postsynapse

The part of a synapse that is part of the post-synaptic cell.

AKT1, SNCA, GSK3B, MEF2C, FMR1, PPP3CA, RAB3GAP1, SLC29A1, GHRL

GO:0098821

MF

BMP receptor activity

Combining with a member of the bone morphogenetic protein (BMP) family, and transmitting a signal across the plasma membrane to initiate a change in cell activity.

ACVR2A, BMPR1A, BMPR2

GO:0098829

BP

intestinal folate absorption

Uptake of folic into the blood by absorption from the small intestine.

SLC46A1

GO:0098838

BP

reduced folate transmembrane transport

The directed movement of reduced folate (dihydrofolate, tetrahydrofolate, methylene-tetrahydrofolate or methyl-tetrahydrofolate) across a membrane.

SLC19A1

GO:0098847

MF

sequence-specific single stranded DNA binding

Interacting selectively and non-covalently with single-stranded DNA of a specific nucleotide composition.

HSF1, PCBP1

GO:0098857

CC

membrane microdomain

A membrane region with a lipid composition that is distinct from that of the membrane regions that surround it.

LAMP2

GO:0098868

BP

bone growth

The increase in size or mass of a bone that contributes to the shaping of that bone.

LEP, LEPR

GO:0098869

BP

cellular oxidant detoxification

Any process carried out at the cellular level that reduces or removes the toxicity superoxide radicals or hydrogen peroxide.

MGST3, GSTZ1, GSR, HP, APOE, ALB, S100A9, GPX1, GSTA1, GSTP1, MGST1, GPX3, PTGS1, GSTM2, PRDX6, GSTT1, PTGS2, GPX4, SESN2, HBB, HBA1, GSTO1, PRDX4, TXNRD1, AAED1, GPX8, CYGB, IPCEF1, TP53INP1, GPX7, MGST2, VIMP, FAM213A, GSTO2, DUOX2, DUOX1, GSTK1, SESN1

GO:0098883

BP

synapse disassembly

A cellular process that results in the controlled breakdown of synapse.

DKK1

GO:0098901

BP

regulation of cardiac muscle cell action potential

Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a cardiac muscle cell. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.

CAMK2D

GO:0098903

BP

regulation of membrane repolarization during action potential

Any process that modulates the rate, frequency or extent of membrane repolarization during an action potential. Membrane repolarization is the process in which membrane potential changes in the repolarizing direction, towards the resting potential.

CACNB3, CACNA2D1, CAV1

GO:0098904

BP

regulation of AV node cell action potential

Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in an atrioventricular node myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.

GJA5, RYR2

GO:0098905

BP

regulation of bundle of His cell action potential

Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a cardiac muscle cell of the bundle of His. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.

GJA5

GO:0098906

BP

regulation of Purkinje myocyte action potential

Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a Purkinje myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.

GJA5

GO:0098907

BP

regulation of SA node cell action potential

Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in an SA node cardiac myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.

ANK2, RYR2

GO:0098908

BP

regulation of neuronal action potential

Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a neuron. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.

FGF12, FMR1

GO:0098909

BP

regulation of cardiac muscle cell action potential involved in regulation of contraction

Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a cardiac muscle cell contributing to the regulation of its contraction.

ATP2A2, CAV1, CAMK2D

GO:0098910

BP

regulation of atrial cardiac muscle cell action potential

Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in an atrial cardiac muscle cell contributing to the regulation of its contraction. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.

GJA5, ANK2, RYR2

GO:0098911

BP

regulation of ventricular cardiac muscle cell action potential

Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a ventricular cardiac muscle cell contributing to the regulation of its contraction. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.

JUP, DSP, DSC2, CAV1, CACNA1C, DSG2, RYR2, PKP2

GO:0098912

BP

membrane depolarization during atrial cardiac muscle cell action potential

The process in which atrial cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential.

CACNA1C

GO:0098915

BP

membrane repolarization during ventricular cardiac muscle cell action potential

The process in which ions are transported across a membrane such that the ventricular cardiomyocyte membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential.

KCNH2

GO:0099053

CC

activating signal cointegrator 1 complex

A protein complex that contains TRIP4 (ASC1) and acts a transcriptional coactivator by interacting with transcription factors such as NF-kappa B. In humans this complex has 4 subunits: TRIP4 + ASCC1-3.

ASCC3, ASCC2

GO:0099054

BP

presynapse assembly

The aggregation, arrangement and bonding together of a set of components to form a presynapse.

WNT5A

GO:0099068

BP

postsynapse assembly

The aggregation, arrangement and bonding together of a set of components to form a postsynapse.

WNT5A

GO:0099073

CC

mitochondrion-derived vesicle

A vesicle derived via budding from a mitochondrion. These vesicles often contain inner membrane and, much more rarely, cristae.

PARK2

GO:0099074

BP

mitochondrion to lysosome transport

Transport from the mitochondrion to the lysosome, mediated by mitochondrion-derived vesicles

PARK2

GO:0099078

CC

BORC complex

A protein complex that is invovled in positioning of the lysosome within the cytoplasm and which is composed of BLOC1S1, BLOC1S2, BORCS5, BORCS6, BORCS7, BORCS8, KXD1 and SNAPIN. The BORC complex recruits ARL8 at the cytosolic face of lysosomes and couples them to microtubule plus-end-directed kinesin motors.

SNAPIN, BLOC1S1, LOH12CR1, BORCS7, BORCS6

GO:0099503

CC

secretory vesicle

A cytoplasmic, membrane bound vesicle that is capable of fusing to the plasma membrane to release its contents into the extracellular space.

DYNLT1

GO:0099565

BP

chemical synaptic transmission, postsynaptic

The part of synaptic transmission occurring in the post-synapse: a signal transduction pathway consisting of neurotransmitter receptor activation and its effects on postsynaptic membrane potential and the ionic composition of the postsynaptic cytosol.

DRD2, AKT1, GSK3B

GO:0099607

BP

lateral attachment of mitotic spindle microtubules to kinetochore

The cell cycle process in which sister chromatids become laterally attached to spindle microtubules as part of mitotic metaphase plate congression. Attachment precedes migration along microtubules towards the spindle equator (metaphase plate).

CENPE

GO:0099639

BP

neurotransmitter receptor transport, endosome to plasma membrane

The directed movement of neurotransmitter receptor from the endosome to the plasma membrane in transport vesicles.

VPS35

GO:0100002

BP

negative regulation of protein kinase activity by protein phosphorylation

Any protein phosphorylation process that negatively_regulates protein kinase activity

AKT1

GO:0101020

MF

estrogen 16-alpha-hydroxylase activity

Catalysis of the reaction: estrogen + donor-H2 + O2 = 16-alpha-hydroxyestrogen + H2O.

CYP1A1, CYP3A4, CYP3A5, CYP3A7

GO:0102007

MF

acyl-L-homoserine-lactone lactonohydrolase activity

Catalysis of the reaction: H2O + an N-acyl-L-homoserine lactone <=> H+ + an N-acyl-L-homoserine.

PON1

GO:0102132

MF

3-oxo-pimeloyl-[acp] methyl ester reductase activity

Catalysis of the reaction: NADP + a 3R-hydroxypimeloyl-[acp] methyl ester <=> NADPH + H+ + a 3-oxo-pimeloyl-[acp] methyl ester.

FASN

GO:0102336

MF

3-oxo-arachidoyl-CoA synthase activity

Catalysis of the reaction: stearoyl-CoA(4-) + malonyl-CoA(5-) + H+ <=> 3-oxoicosanoyl-CoA. + carbon dioxide + coenzyme A.

ELOVL7, ELOVL1, ELOVL4, ELOVL6, ELOVL5

GO:0102337

MF

3-oxo-cerotoyl-CoA synthase activity

Catalysis of the reaction: tetracosanoyl-CoA(4-) + malonyl-CoA(5-) + H+ <=> 3-oxohexacosanoyl-CoA + carbon dioxide + coenzyme A.

ELOVL7, ELOVL1, ELOVL4, ELOVL6, ELOVL5

GO:0102338

MF

3-oxo-lignoceronyl-CoA synthase activity

Catalysis of the reaction: behenoyl-CoA(4-) + malonyl-CoA(5-) + H+ <=> 3-oxotetracosanoyl-CoA. + carbon dioxide + coenzyme A.

ELOVL7, ELOVL1, ELOVL4, ELOVL6, ELOVL5

GO:0102339

MF

3-oxo-arachidoyl-CoA reductase activity

Catalysis of the reaction: (R)-3-hydroxyicosanoyl-CoA(4-) + NADP(3-) <=> 3-oxoicosanoyl-CoA + NADPH + H+.

HSD17B12

GO:0102340

MF

3-oxo-behenoyl-CoA reductase activity

Catalysis of the reaction: (R)-3-hydroxybehenoyl-CoA(4-) + NADP(3-) <=> 3-oxodocosanoyl-CoA + NADPH + H+.

HSD17B12

GO:0102341

MF

3-oxo-lignoceroyl-CoA reductase activity

Catalysis of the reaction: (R)-3-hydroxylignoceroyl-CoA + NADP <=> 3-oxotetracosanoyl-CoA + NADPH + H+.

HSD17B12

GO:0102344

MF

3-hydroxy-behenoyl-CoA dehydratase activity

Catalysis of the reaction: (R)-3-hydroxybehenoyl-CoA <=> trans-2-docosenoyl-CoA + H2O.

HACD1, HACD4, HACD2, HACD3

GO:0102345

MF

3-hydroxy-lignoceroyl-CoA dehydratase activity

Catalysis of the reaction: (R)-3-hydroxylignoceroyl-CoA(4-) <=> trans-2-tetracosenoyl-CoA + H2O.

HACD1, HACD4, HACD2, HACD3

GO:0102390

MF

mycophenolic acid acyl-glucuronide esterase activity

Catalysis of the reaction: mycophenolic acid O-acyl-glucuronide(1-) + H2O <=> mycophenolate + H+ + D-glucopyranuronate

ABHD10

GO:0102391

MF

decanoate--CoA ligase activity

Catalysis of the reaction: decanoate + ATP(4-) + coenzyme A(4-) <=> decanoyl-CoA(4-) + AMP(2-) + diphosphoric acid

SLC27A2, ACSL4, ACSL1, ACSL6

GO:1900004

BP

negative regulation of serine-type endopeptidase activity

Any process that stops, prevents or reduces the frequency, rate or extent of serine-type endopeptidase activity.

SPINK1, CR1

GO:1900005

BP

positive regulation of serine-type endopeptidase activity

Any process that activates or increases the frequency, rate or extent of serine-type endopeptidase activity.

CR1

GO:1900006

BP

positive regulation of dendrite development

Any process that activates or increases the frequency, rate or extent of dendrite development.

OPA1, COBL, CLIP1, IQGAP1, VLDLR, EZH2, PACSIN1, IL1RAP, TMEM106B

GO:1900015

BP

regulation of cytokine production involved in inflammatory response

Any process that modulates the frequency, rate or extent of cytokine production involved in inflammatory response.

PER1, LEP, MAPK14

GO:1900016

BP

negative regulation of cytokine production involved in inflammatory response

Any process that stops, prevents or reduces the frequency, rate or extent of cytokine production involved in inflammatory response.

APOD, IL1R2, C5orf30

GO:1900017

BP

positive regulation of cytokine production involved in inflammatory response

Any process that activates or increases the frequency, rate or extent of cytokine production involved in inflammatory response.

CD6, GPSM3

GO:1900020

BP

positive regulation of protein kinase C activity

Any process that activates or increases the frequency, rate or extent of protein kinase C activity.

WNT5A, CEMIP

GO:1900024

BP

regulation of substrate adhesion-dependent cell spreading

Any process that modulates the frequency, rate or extent of substrate adhesion-dependent cell spreading.

PTK2, CORO1C

GO:1900025

BP

negative regulation of substrate adhesion-dependent cell spreading

Any process that stops, prevents or reduces the frequency, rate or extent of substrate adhesion-dependent cell spreading.

ITGB1BP1, ACTN4, MFI2, FBLN1, GBP1, EFNA5, KANK1, POSTN, CORO1C

GO:1900026

BP

positive regulation of substrate adhesion-dependent cell spreading

Any process that activates or increases the frequency, rate or extent of substrate adhesion-dependent cell spreading.

ARPC2, APOA1, FGA, FGB, FGG, FLNA, CALR, CRKL, LIMS1, RAC3, S100A10, CDC42, RAC1, C1QBP, ARHGEF7, LRRC16A, OLFM4, NET1, HAS2, MYADM, CIB1, TRIOBP, DOCK5

GO:1900027

BP

regulation of ruffle assembly

Any process that modulates the frequency, rate or extent of ruffle assembly.

ICAM1, RDX, CAV1, SH3YL1, CORO1C

GO:1900028

BP

negative regulation of ruffle assembly

Any process that stops, prevents or reduces the frequency, rate or extent of ruffle assembly.

KANK1, EVL

GO:1900029

BP

positive regulation of ruffle assembly

Any process that activates or increases the frequency, rate or extent of ruffle assembly.

COBL, PFN1, NLGN1

GO:1900034

BP

regulation of cellular response to heat

Any process that modulates the frequency, rate or extent of cellular response to heat.

NUPL2, DNAJB6, HSBP1, NUP155, BAG2, CRYAB, HSP90AA1, HSP90AB1, HSPA1A, HSPA1B, TPR, DNAJB1, MAPK3, MAPK1, HSPA1L, RPA3, NUP62, MAPKAPK2, NUP153, RANBP2, GSK3B, NUP107, YWHAE, RAE1, HSF1, FKBP4, EP300, NUP160, CAMK2D, PTGES3, C11orf73, CCAR2, NUP93, NUP43, NUP37, NUP35, NUP210, HSPH1, NUP205, CREBBP, SEH1L, NUP88, DNAJC7, NDC1, MLST8, NUP58, NUP85, CHORDC1, NUP50, BAG5

GO:1900037

BP

regulation of cellular response to hypoxia

Any process that modulates the frequency, rate or extent of cellular response to hypoxia.

AJUBA, CHCHD2

GO:1900041

BP

negative regulation of interleukin-2 secretion

Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-2 secretion.

EZR, GBP1