| GO ID | Ontology | GO Term | Term Definition |
Proteins |
GO:0071532 | MF | ankyrin repeat binding | Interacting selectively and non-covalently with an ankyrin repeat of a protein. Ankyrin repeats are tandemly repeated modules of about 33 amino acids; each repeat folds into a helix-loop-helix structure with a beta-hairpin/loop region projecting out from the helices at a 90-degree angle, and repeats stack to form an L-shaped structure. |
RELA |
GO:0071535 | MF | RING-like zinc finger domain binding | Interacting selectively and non-covalently with a RING-like zinc finger domain domain of a protein. The RING-like domain is a zinc finger domain that is related to the C3HC4 RING finger domain. |
UBE2I |
GO:0071539 | BP | protein localization to centrosome | A process in which a protein is transported to, or maintained at, the centrosome. |
AURKA, CSNK1D, DCTN2, PCM1, STIL, CCDC14, HOOK3, PIBF1, SPAG5, CEP83 |
GO:0071540 | CC | eukaryotic translation initiation factor 3 complex, eIF3e | An eukaryotic translation initiation factor 3 complex that contains the PCI-domain protein eIF3e. |
EIF3A |
GO:0071541 | CC | eukaryotic translation initiation factor 3 complex, eIF3m | An eukaryotic translation initiation factor 3 complex that contains the PCI-domain protein eIF3m. |
EIF3B, EIF3A |
GO:0071542 | BP | dopaminergic neuron differentiation | The process in which a neuroblast acquires the specialized structural and functional features of a dopaminergic neuron, a neuron that secretes dopamine. |
LRP6, VEGFA, OTX2, NR4A2, HIF1A, SFRP1 |
GO:0071543 | BP | diphosphoinositol polyphosphate metabolic process | The chemical reactions and pathways involving a diphosphoinositol polyphosphate, 1,2,3,4,5,6-cyclohexanehexol with one or more diphosphate groups and multiple monophosphate groups attached. |
NUDT10, NUDT11 |
GO:0071544 | BP | diphosphoinositol polyphosphate catabolic process | The chemical reactions and pathways resulting in the breakdown of a diphosphoinositol polyphosphate, 1,2,3,4,5,6-cyclohexanehexol with one or more diphosphate groups and multiple monophosphate groups attached. |
NUDT3 |
GO:0071547 | CC | piP-body | A P granule that contains the PIWIL4-TDRD9 module, a set of proteins that act in the secondary piRNA pathway. |
PIWIL4, TDRD9 |
GO:0071548 | BP | response to dexamethasone | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dexamethasone stimulus. |
FOXO3, EDN1, PCNA, PTAFR, PCK2 |
GO:0071549 | BP | cellular response to dexamethasone stimulus | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dexamethasone stimulus. |
MSTN, EGFR, ASS1, TGFB1, IL6, CCL2, SRD5A1, SERPINF1, STAR, AGTR2, CASP9, RPL32, HNRNPU, FOXO1, FBXO32, SMYD3, DNMT3B, ERRFI1 |
GO:0071550 | BP | death-inducing signaling complex assembly | A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by a death domain (DD) interaction, as part of the extrinsic apoptotic signaling pathway. |
TNF, RAF1, FADD, RIPK1, CASP8, TRADD |
GO:0071554 | BP | cell wall organization or biogenesis | A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cell wall. |
SPATA20 |
GO:0071556 | CC | integral component of lumenal side of endoplasmic reticulum membrane | The component of the endoplasmic reticulum membrane consisting of the gene products that penetrate only the lumenal side of the membrane. |
HLA-B, HLA-DRA, HLA-DQA2, HLA-DQA1, HLA-DQB1, CD74, HLA-E, HLA-DRB4, HLA-G, HLA-DPA1, CALR, CANX, HLA-A, HLA-F, BCAP31, HLA-DRB3, PKD2, HLA-DRB5, SPPL3, SPPL2A, HM13 |
GO:0071557 | BP | histone H3-K27 demethylation | The modification of histone H3 by the removal of a methyl group from lysine at position 27 of the histone. |
UTY, KDM6A, KDM7A |
GO:0071558 | MF | histone demethylase activity (H3-K27 specific) | Catalysis of the removal of a methyl group from lysine at position 27 of the histone H3 protein. |
UTY, KDM6A, KDM7A |
GO:0071559 | BP | response to transforming growth factor beta | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transforming growth factor beta stimulus. |
SMAD4, RUNX3, ZFHX3, CITED1 |
GO:0071560 | BP | cellular response to transforming growth factor beta stimulus | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transforming growth factor beta stimulus. |
PDCD5, SMAD7, TGFB1, PENK, COL1A1, EDN1, CLEC3B, FYN, COL4A2, WNT2, FBN1, SOX6, TGFBR1, WNT5A, ZFP36L2, LIMS1, SOX9, STAR, CAV1, MEF2C, ZFP36L1, HYAL2, MAPK7, PDE3A, POSTN, ANKRD1, SFRP1, HDAC2, PDGFD, NOX4, PPARGC1A |
GO:0071561 | CC | nucleus-vacuole junction | An organelle membrane contact site formed between the vacuole membrane and the outer nuclear membrane. In S. cerevisiae these contacts are mediated through direct physical interaction between Vac8p and Nvj1p. |
PIK3R4 |
GO:0071564 | CC | npBAF complex | A SWI/SNF-type complex that is found in neural stem or progenitor cells, and in human contains actin and proteins encoded by the ARID1A/BAF250A or ARID1B/BAF250B, SMARCD1/BAF60A, SMARCD3/BAF60C, SMARCA2/BRM/BAF190B, SMARCA4/BRG1/BAF190A, SMARCB1/BAF47, SMARCC1/BAF155, SMARCE1/BAF57, SMARCC2/BAF170, PHF10/BAF45A, ACTL6A/BAF53A genes. The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. |
ARID1A, ACTL6A, SMARCA2, SMARCA4, SMARCD3, SMARCC2, PHF10, SMARCC1, SMARCD1 |
GO:0071565 | CC | nBAF complex | A SWI/SNF-type complex that is found in post-mitotic neurons, and in human contains actin and proteins encoded by the ARID1A/BAF250A or ARID1B/BAF250B, SMARCD1/BAF60A, SMARCD3/BAF60C, SMARCA2/BRM/BAF190B, SMARCA4/BRG1/BAF190A, SMARCB1/BAF47, SMARCC1/BAF155, SMARCE1/BAF57, SMARCC2/BAF170, DPF1/BAF45B, DPF3/BAF45C, ACTL6B/BAF53B genes. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth. |
ARID1A, SMARCA2, SMARCA4, SMARCD3, ARID1B, SMARCC2, DPF3, SMARCC1, SMARCD1 |
GO:0071566 | MF | UFM1 activating enzyme activity | Catalysis of the activation of the small ubiquitin-related modifier UFM1, through the formation of an ATP-dependent high-energy thiolester bond. |
UBA5 |
GO:0071567 | MF | UFM1 hydrolase activity | Catalysis of the hydrolysis of UFM1, a small ubiquitin-related modifier, from previously modified substrates. |
UFSP2 |
GO:0071569 | BP | protein ufmylation | Covalent attachment of the ubiquitin-like protein UFM1 to another protein. |
UFM1, UBA5 |
GO:0071577 | BP | zinc II ion transmembrane transport | A process in which a zinc II ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. |
SLC39A6, SLC39A14, SLC30A8, SLC30A1 |
GO:0071578 | BP | zinc II ion transmembrane import | The directed movement of zinc II ions across a membrane into a cell or organelle. |
SLC39A6, SLC39A14, SLC39A4, SLC39A8, SLC39A10 |
GO:0071584 | BP | negative regulation of zinc ion transmembrane import | Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of zinc ions (Zn2+) from one side of a membrane to the other. |
SLC30A1 |
GO:0071585 | BP | detoxification of cadmium ion | Any process that reduces or removes the toxicity of cadmium ion. These may include transport of cadmium away from sensitive areas and to compartments or complexes whose purpose is sequestration of cadmium ion. |
SLC30A1 |
GO:0071586 | BP | CAAX-box protein processing | The second process in a series of specific posttranslational modifications to the CAAX box region of CAAX box proteins, in which the last three amino acids of the protein (AAX) are removed by proteolysis. |
RCE1 |
GO:0071593 | BP | lymphocyte aggregation | The adhesion of one lymphocyte to one or more other lymphocytes via adhesion molecules. |
RAC2 |
GO:0071595 | CC | Nem1-Spo7 phosphatase complex | A protein serine/threonine phosphatase complex that is involved in nuclear envelope organization, and contains proteins known in budding yeast as Nem1p and Spo7p. |
CTDNEP1, CNEP1R1 |
GO:0071596 | BP | ubiquitin-dependent protein catabolic process via the N-end rule pathway | The chemical reactions and pathways resulting in the breakdown of a protein or peptide covalently tagged with ubiquitin, via the N-end rule pathway. In the N-end rule pathway, destabilizing N-terminal residues (N-degrons) in substrates are recognized by E3 ligases (N-recognins), whereupon the substrates are linked to ubiquitin and then delivered to the proteasome for degradation. |
UBR3, UBR1 |
GO:0071598 | CC | neuronal ribonucleoprotein granule | A ribonucleoprotein complex that is found in the cytoplasm of axons and dendrites, and transports translationally silenced mRNAs to dendritic synapses, where they are released and translated in response to specific exogenous stimuli. |
PQBP1, FMR1, UHMK1 |
GO:0071599 | BP | otic vesicle development | The process whose specific outcome is the progression of the otic vesicle over time, from its formation to the mature structure. The otic vesicle is a transient embryonic structure formed during development of the vertebrate inner ear. |
PAX8, AHI1 |
GO:0071603 | BP | endothelial cell-cell adhesion | The attachment of an endothelial cell to another endothelial cell via adhesion molecules. |
JUP, THBS4, CYP1B1 |
GO:0071609 | BP | chemokine (C-C motif) ligand 5 production | The appearance of chemokine (C-C motif) ligand 5 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. |
TUSC2 |
GO:0071621 | BP | granulocyte chemotaxis | The movement of a granulocyte in response to an external stimulus. |
ANXA1, CCL3 |
GO:0071622 | BP | regulation of granulocyte chemotaxis | Any process that modulates the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus. |
CAMK1D |
GO:0071624 | BP | positive regulation of granulocyte chemotaxis | Any process that increases the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus. |
S100A7 |
GO:0071625 | BP | vocalization behavior | The behavior in which an organism produces sounds by a mechanism involving its respiratory system. |
SRPX2, DLG4, NLGN4X, NRXN1 |
GO:0071629 | BP | cytoplasm-associated proteasomal ubiquitin-dependent protein catabolic process | The chemical reactions and pathways resulting in the breakdown of misfolded proteins in the cytoplasm, which are targeted to cytoplasmic proteasomes for degradation. |
RNF126 |
GO:0071636 | BP | positive regulation of transforming growth factor beta production | Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta. |
CD46, PTGS2 |
GO:0071638 | BP | negative regulation of monocyte chemotactic protein-1 production | Any process that stops, prevents, or reduces the frequency, rate, or extent of production of monocyte chemotactic protein-1. |
SOCS5, APOD, GSTP1, NR1H4, C1QTNF3 |
GO:0071639 | BP | positive regulation of monocyte chemotactic protein-1 production | Any process that activates or increases the frequency, rate, or extent of production of monocyte chemotactic protein-1. |
IL1A, IL1B, TWIST1, ADIPOQ, TRPV4 |
GO:0071642 | BP | positive regulation of macrophage inflammatory protein 1 alpha production | Any process that activates or increases the frequency, rate, or extent of production of macrophage inflammatory protein 1 alpha. |
TRPV4 |
GO:0071650 | BP | negative regulation of chemokine (C-C motif) ligand 5 production | Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-C motif) ligand 5. |
IL10 |
GO:0071651 | BP | positive regulation of chemokine (C-C motif) ligand 5 production | Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-C motif) ligand 5. |
DDX3X, MAVS, TRPV4 |
GO:0071660 | BP | positive regulation of IP-10 production | Any process that activates or increases the frequency, rate, or extent of production of IP-10. |
MAVS |
GO:0071663 | BP | positive regulation of granzyme B production | Any process that activates or increases the frequency, rate, or extent of production of granzyme B. |
CD244 |
GO:0071665 | CC | gamma-catenin-TCF7L2 complex | A protein complex that contains gamma-catenin and TCF7L2 (TCF4), binds to the TCF DNA motif within a promoter element, and is involved in the regulation of WNT target gene transcription. |
JUP |
GO:0071670 | BP | smooth muscle cell chemotaxis | The directed movement of a smooth muscle cell in response to an external stimulus. |
PDGFRB, PARVA |
GO:0071672 | BP | negative regulation of smooth muscle cell chemotaxis | Any process that stops, prevents, or reduces the frequency, rate, or extent of smooth muscle cell chemotaxis. |
SLIT2, GSTP1, CORO1B |
GO:0071673 | BP | positive regulation of smooth muscle cell chemotaxis | Any process that activates or increases the frequency, rate, or extent of smooth muscle cell chemotaxis. |
PDGFD |
GO:0071674 | BP | mononuclear cell migration | The movement of a mononuclear cell within or between different tissues and organs of the body. |
LGALS3 |
GO:0071676 | BP | negative regulation of mononuclear cell migration | Any process that decreases the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body. |
SLIT2 |
GO:0071677 | BP | positive regulation of mononuclear cell migration | Any process that increases the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body. |
TGFB1, TNF, LGALS3 |
GO:0071679 | BP | commissural neuron axon guidance | The process in which the migration of an axon growth cone of a commissural neuron is directed to its target in the brain in response to a combination of attractive and repulsive cues. |
NFIB, NRP1, VEGFA, EPHB2, DAG1 |
GO:0071681 | BP | cellular response to indole-3-methanol | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an indole-3-methanol stimulus. |
JUP, CTNNA1, CTNNB1, BRCA1 |
GO:0071682 | CC | endocytic vesicle lumen | The volume enclosed by the membrane of an endocytic vesicle. |
HP, APOA1, APOE, APOB, HSP90AA1, SPARC, SAA1, HSP90B1, CALR, HBB, HBA1, HSPH1, HYOU1 |
GO:0071691 | BP | cardiac muscle thin filament assembly | The aggregation, arrangement and bonding together of proteins to form the actin-based thin filaments of myofibrils in cardiac muscle. |
NEBL |
GO:0071701 | BP | regulation of MAPK export from nucleus | Any process that modulates the frequency, rate or extent of the directed movement of a MAP kinase from the nucleus to the cytoplasm. |
DNAJC27 |
GO:0071709 | BP | membrane assembly | The aggregation, arrangement and bonding together of a set of components to form a membrane. |
SPTBN1, ANK3 |
GO:0071711 | BP | basement membrane organization | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the basement membrane. |
FLRT2, SPINT2, NID1, MMP11, NID2, DAG1 |
GO:0071712 | BP | ER-associated misfolded protein catabolic process | The chemical reactions and pathways resulting in the breakdown of misfolded proteins transported from the endoplasmic reticulum and targeted to cytoplasmic proteasomes for degradation. |
TOR1A, VCP, UFD1L, SDF2, UGGT1, POMT1 |
GO:0071723 | MF | lipopeptide binding | Interacting selectively and non-covalently with a lipopeptide, any of a group of organic compounds comprising two or more amino acids linked by peptide bonds and containing a nonprotein group consisting of a lipid or lipids. |
CD1D, TLR1 |
GO:0071726 | BP | cellular response to diacyl bacterial lipopeptide | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diacylated bacterial lipopeptide stimulus. |
TLR2, CD14, CD36 |
GO:0071727 | BP | cellular response to triacyl bacterial lipopeptide | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triacylated bacterial lipopeptide stimulus. |
TLR2, CD14, TLR1 |
GO:0071732 | BP | cellular response to nitric oxide | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitric oxide stimulus. |
AIFM1, CCNA2, CDK2, MT3, FOXO1, HNRNPD, MTR |
GO:0071733 | BP | transcriptional activation by promoter-enhancer looping | The formation and maintenance of DNA loops that juxtapose the promoter and enhancer regions of RNA polymerase II-transcribed genes and activate transcription from an RNA polymerase II promoter. |
RUVBL2 |
GO:0071763 | BP | nuclear membrane organization | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear inner or outer membrane. |
TOR1A, TMEM43 |
GO:0071765 | BP | nuclear inner membrane organization | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear inner membrane. |
TARDBP |
GO:0071773 | BP | cellular response to BMP stimulus | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bone morphogenetic protein (BMP) stimulus. |
SMAD9, SPINT2, BMP2, BMP4, BMP6, ACVR2A, BMPR1A, DLX5, ADAMTS12, ACVR1, SMAD4, BMPR2, RUNX2, SFRP1, GATA6, HEYL, ADAMTS7 |
GO:0071774 | BP | response to fibroblast growth factor | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fibroblast growth factor stimulus. |
PTH, ELK1, TNC, IER2 |
GO:0071782 | CC | endoplasmic reticulum tubular network | A subcompartment of the endoplasmic reticulum consisting of tubules having membranes with high curvature in cross-section. |
REEP5, KPNB1, RAB3GAP1, ATL3, LNP, REEP1 |
GO:0071786 | BP | endoplasmic reticulum tubular network organization | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum (ER) tubular network. The ER tubular network is the ER part that that has membranes with high curvature in cross-section. |
TMEM170A, LNP, REEP1, RTN4 |
GO:0071787 | BP | endoplasmic reticulum tubular network assembly | The aggregation, arrangement and bonding together of a set of components to form the endoplasmic reticulum (ER) tubular network. The ER tubular network is the ER part that comprises the membranes with high curvature in cross-section. |
ARL6IP1, RTN4 |
GO:0071797 | CC | LUBAC complex | A ubiquitin ligase complex that catalyzes linear head-to-tail polyubiquitin conjugation on its targets. In human the complex consists of RBCK1, RNF31 and SHARPIN, and has an MW of approximately 600 kDa, suggesting a heteromultimeric assembly of its subunits. LUBAC stands for Linear Ubiquitin Chain Assembly Complex. |
PARK2 |
GO:0071799 | BP | cellular response to prostaglandin D stimulus | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin D stimulus. |
TNC, AKR1C3, PTGFR, AKR1C2, PTGDR |
GO:0071800 | BP | podosome assembly | The aggregation, arrangement and bonding together of a set of components to form a podosome, an actin-rich adhesion structure characterized by formation upon cell substrate contact and localization at the substrate-attached part of the cell. |
SH3PXD2B, FARP2, BIN2 |
GO:0071803 | BP | positive regulation of podosome assembly | Any process that activates or increases the rate or extent of podosome assembly. |
TNF, LCP1, MAPK9, ARHGEF5, FSCN1 |
GO:0071805 | BP | potassium ion transmembrane transport | A process in which a potassium ion is transported from one side of a membrane to the other. |
KCNK1, KCNK3, CNGA1, FXYD4, KCNA1, KCNMA1, KCNH2, PKD2, KCNC3, KCNJ11, KCNG3, KCNV2, KCNE4, SLC9A6, KCNK17, KCNK12, KCNIP2, TMEM38B, SLC9A2, KCNG1, KCNK6 |
GO:0071806 | BP | protein transmembrane transport | The directed movement of a protein across a membrane by means of some agent such as a transporter or pore. |
AZGP1, SEC61G, NUTF2, MCL1 |
GO:0071812 | BP | positive regulation of fever generation by positive regulation of prostaglandin secretion | Any process that increases the rate or extent of fever generation via positive regulation of the frequency, rate or extent of the regulated release of a prostaglandin from a cell. |
TNFSF11, TNFRSF11A |
GO:0071813 | MF | lipoprotein particle binding | Interacting selectively and non-covalently with a lipoprotein particle. A lipoprotein particle, also known as a lipoprotein, is a clathrate complex consisting of a lipid enwrapped in a protein host without covalent binding in such a way that the complex has a hydrophilic outer surface consisting of all the protein and the polar ends of any phospholipids. |
APOE, MAPT, CD36, CDH13 |
GO:0071816 | BP | tail-anchored membrane protein insertion into ER membrane | A process of protein insertion into the endoplasmic reticulum (ER) membrane in which a tail-anchored (TA) transmembrane protein is incorporated into an endoplasmic reticulum (ER) membrane. TA transmembrane protein, also named type II transmembrane proteins, contain a single C- terminal transmembrane region. |
WRB |
GO:0071817 | CC | MMXD complex | A protein complex that contains the proteins MMS19, MIP18 and XPD, localizes to mitotic spindle during mitosis, and is required for proper chromosome segregation. |
CIAO1, SLC25A5, ERCC2, FAM96B |
GO:0071819 | CC | DUBm complex | A protein complex that forms part of SAGA-type complexes SAGA and SLIK, and mediates deubiquitination of histone H2B. In S. cerevisiae, the DUBm consists of the proteins Ubp8p, Sgf11p, Sus1p, and Sgf73p. |
ENY2 |
GO:0071820 | MF | N-box binding | Interacting selectively and non-covalently with an N-box, a DNA motif with the consensus sequence CACNAG that is found in the promoters of genes expressed preferentially at synapses. |
HES1 |
GO:0071821 | CC | FANCM-MHF complex | A protein complex contains the proteins FANCM and MHF, or their orthologs, plays an essential role in DNA remodeling, protects replication forks, and is conserved in eukaryotes. |
STRA13, FANCM, APITD1 |
GO:0071837 | MF | HMG box domain binding | Interacting selectively and non-covalently with an HMG box domain, a protein domain that consists of three helices in an irregular array. HMG-box domains are found in one or more copies in HMG-box proteins, which form a large, diverse family involved in the regulation of DNA-dependent processes such as transcription, replication, and strand repair, all of which require the bending and unwinding of chromatin. |
HOXA3, JUN, HOXC4, EGR2, MEOX1, DLX5, HHEX, MEF2C, TCF12 |
GO:0071838 | BP | cell proliferation in bone marrow | The multiplication or reproduction of cells, resulting in the expansion of a cell population in the bone marrow. |
ACE |
GO:0071847 | BP | TNFSF11-mediated signaling pathway | A series of molecular signals initiated by the binding of tumor necrosis factor ligand superfamily member 11 (TNFSF11) to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. |
TNFSF11, TNFRSF11A |
GO:0071848 | BP | positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling | Any TNFSF11-mediated signaling process that increases the rate, frequency, or extent of the ERK1 and ERK2 cascade. |
TNFSF11, TNFRSF11A |
GO:0071850 | BP | mitotic cell cycle arrest | The process in which the mitotic cell cycle is halted during one of the normal phases (G1, S, G2, M). |
GADD45A, DUSP1, CDKN1A, CDKN1B, MAGI2, MCPH1, GADD45GIP1, PNPT1, RGCC, CDC14A |
GO:0071862 | MF | protein phosphatase type 1 activator activity | Increases the activity of the enzyme protein phosphatase type 1. |
PPP1R15A, PHACTR4 |
GO:0071864 | BP | positive regulation of cell proliferation in bone marrow | A process that activates or increases the frequency, rate or extent of cell proliferation in the bone marrow. |
PTH, IL6, MEF2C |
GO:0071866 | BP | negative regulation of apoptotic process in bone marrow | Any process that stops, prevents, or reduces the frequency, rate or extent of the occurrence or rate of cell death by apoptotic process in the bone marrow. |
PTH, HSPD1 |
GO:0071870 | BP | cellular response to catecholamine stimulus | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catecholamine stimulus. A catecholamine is any of a group of biogenic amines that includes 4-(2-aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution. |
GNB1, NR4A3 |
GO:0071871 | BP | response to epinephrine | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epinephrine stimulus. Epinephrine is a catecholamine that has the formula C9H13NO3; it is secreted by the adrenal medulla to act as a hormone, and released by certain neurons to act as a neurotransmitter active in the central nervous system. |
PENK, PPARGC1A |
GO:0071872 | BP | cellular response to epinephrine stimulus | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epinephrine stimulus. Epinephrine is a catecholamine that has the formula C9H13NO3; it is secreted by the adrenal medulla to act as a hormone, and released by certain neurons to act as a neurotransmitter active in the central nervous system. |
PRKACA, SRD5A1, ATP2B4, SNCA, STAR, PDE4D, ADIPOQ, SIRT2, RYR2 |