Search Geneontologies

Geneontologies

GO ID Ontology GO Term Term Definition Proteins

GO:0071314

BP

cellular response to cocaine

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cocaine stimulus. Cocaine is a crystalline alkaloid obtained from the leaves of the coca plant.

CCNA2

GO:0071316

BP

cellular response to nicotine

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nicotine stimulus.

TNF, NTRK1, TH, NFKB1, RELA, KCNJ11, BAD

GO:0071318

BP

cellular response to ATP

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ATP (adenosine 5'-triphosphate) stimulus.

CCL2, HSP90B1, PTGS2, RYR3, TRPV1, P2RX4

GO:0071320

BP

cellular response to cAMP

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) stimulus.

AQP9, KDM1A, AQP8, ASS1, PENK, APP, RPLP0, CFTR, EZR, SRD5A1, WT1, IGFBP5, PTAFR, PCK1, PIK3CG, STAR, STC1, RAP1A, ZFP36L1, AKAP6, RAPGEF1, ITPR2, ADIPOQ, SLC5A5, INPP5K, NOX4

GO:0071321

BP

cellular response to cGMP

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cGMP (cyclic GMP, guanosine 3',5'-cyclophosphate) stimulus.

PDE3A

GO:0071322

BP

cellular response to carbohydrate stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbohydrate stimulus.

PRKCB, RPS6KA2

GO:0071332

BP

cellular response to fructose stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fructose stimulus.

XBP1, SLC2A5, PCK1, PPARGC1A

GO:0071333

BP

cellular response to glucose stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus.

FOXO3, ERN1, ICAM1, TH, LGALS1, NME1, PRKACA, XBP1, NME2, SERPINF1, PIK3CA, GATA4, GCLC, GCLM, STAR, POLG, UCP2, RAP1A, RACK1, MEF2C, SOX4, TJP1, PPP3CA, GAS6, KCNJ11, PCK2, AACS, CPB2, PEO1, GPER1, SLC29A1, NOX4, PPARGC1A, ZNF236, IRS2

GO:0071338

BP

positive regulation of hair follicle cell proliferation

Any process that activates or increases the rate or extent of hair follicle cell proliferation.

CDC42

GO:0071339

CC

MLL1 complex

A protein complex that can methylate lysine-4 of histone H3. MLL1/MLL is the catalytic methyltransferase subunit, and the complex also contains the core components ASH2L, HCFC1/HCF1 WDR5 and RBBP5.

RBBP5, INO80C, MGA, BAP18, PRPF31, PHF20, SENP3, CHD8, ASH2L, RUVBL2, RUVBL1, LAS1L

GO:0071340

BP

skeletal muscle acetylcholine-gated channel clustering

The accumulation of acetylcholine-gated cation channels in a narrow, central region of muscle fibers, in apposition to nerve terminals.

MUSK, ETV5, COLQ

GO:0071344

BP

diphosphate metabolic process

The chemical reactions and pathways involving diphosphate, the anion or salt of diphosphoric acid.

PPA2

GO:0071345

BP

cellular response to cytokine stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus.

HAX1, CSF1R, MME, HCLS1, CXCR4, AKAP6, DPYSL3, PID1, KHSRP

GO:0071346

BP

cellular response to interferon-gamma

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus. Interferon gamma is the only member of the type II interferon found so far.

TLR3, DAPK3, SYNCRIP, ASS1, GAPDH, EDN1, EPRS, CCL3, CCL4, TDGF1, CCL2, CCL5, CD58, HLA-DPA1, MRC1, RPL13A, WNT5A, IL12RB1, STAR, DAPK1, CCL20, CCL8, GBP6

GO:0071347

BP

cellular response to interleukin-1

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-1 stimulus.

FGB, IL6, EDN1, ICAM1, CXCL8, CCL3, TFPI, CCL4, CCL2, CCL5, CEBPB, NFKB1, YY1, RORA, PCK1, CHI3L1, RBMX, SOX9, ADAMTS12, CCL20, CCL8, RELA, HYAL2, ANKRD1, PTGIS, HIF1A, SFRP1, HAS2, TANK, OTUB1, ADAMTS7, PYCARD, KLF2

GO:0071352

BP

cellular response to interleukin-2

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-2 stimulus.

CDC5L

GO:0071353

BP

cellular response to interleukin-4

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-4 stimulus.

RPLP0, HSP90AB1, HSPA5, ALAD, XBP1, MRC1, CORO1A, FASN, MCM2, TUBA1B, NFIL3, SHPK

GO:0071354

BP

cellular response to interleukin-6

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-6 stimulus.

TDGF1, CCL2, NFKB1, PHB, HAMP, RELA, SELPLG, PTGIS, PID1, PPARGC1A, ST3GAL6

GO:0071356

BP

cellular response to tumor necrosis factor

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tumor necrosis factor stimulus.

TNFRSF21, ASS1, COL1A1, APOB, IL6, EDN1, ICAM1, THBS1, CXCL8, CCL3, CCL4, TDGF1, CCL2, CCL5, CD58, VCAM1, ZFP36, RORA, PCK1, CHI3L1, BRCA1, ZFP36L2, HDAC4, ADAMTS12, CCL20, CCL8, HAMP, RELA, ZFP36L1, HYAL2, RIPK1, HDAC1, KCNJ11, POSTN, ANKRD1, PCK2, ZFAND6, PID1, SFRP1, TRPV1, HAS2, TANK, ARHGEF2, GPER1, MAP3K5, CIB1, INPP5K, SMPD4, PPARGC1A, ADAMTS7, PYCARD, KLF2

GO:0071359

BP

cellular response to dsRNA

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a double-stranded RNA stimulus.

NFKB1

GO:0071360

BP

cellular response to exogenous dsRNA

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an exogenous double-stranded RNA stimulus.

TLR3, FLOT1, RALB, CAV1, COLEC12, MAVS

GO:0071361

BP

cellular response to ethanol

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus.

CYBB, ADCY7, ITPR2, TP53INP1

GO:0071363

BP

cellular response to growth factor stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus.

ANGPT2, KLF4, URI1, PDGFB, BGLAP, ERBB2, INSR, TH, PFN1, THBS1, SPARC, SRD5A1, TNFRSF1B, DTYMK, CTNNB1, EMD, STAT5B, RACK1, MDM2, MAP2K5, MAPK7, RIPK1, GAS6, PPP2R5B, TWIST1, TWF2, SFRP1, FEZ1, CIB1, EHD4

GO:0071364

BP

cellular response to epidermal growth factor stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epidermal growth factor stimulus.

SNAI2, ZPR1, EGFR, COL1A1, ERBB2, GSTP1, TDGF1, ZFP36, CAD, AKT1, MCM7, ID1, IQGAP1, ZFP36L2, SOX9, STAT5B, EEF1A1, ZFP36L1, INPP5K, GAREM1, ERRFI1

GO:0071371

BP

cellular response to gonadotropin stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gonadotropin stimulus.

WT1, LHCGR, PAX8, NSMF, GATA6, SLC5A5

GO:0071372

BP

cellular response to follicle-stimulating hormone stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a follicle-stimulating hormone stimulus.

INHBA, NOTCH1, GCLC, GCLM, STAR, EFNA5, HMGCS1, PPARGC1A

GO:0071373

BP

cellular response to luteinizing hormone stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a luteinizing hormone stimulus.

CCNA2, STAR

GO:0071374

BP

cellular response to parathyroid hormone stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a parathyroid hormone stimulus.

PRKACA, HDAC4, MEF2C, SOST

GO:0071375

BP

cellular response to peptide hormone stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals.

CYP11A1, EDN1, FYN, CYP11B1, XBP1, CYP11B2, NFKB1, CSK, MDM2, CAV1, RELA, ZFP36L1, GPER1

GO:0071376

BP

cellular response to corticotropin-releasing hormone stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticotropin-releasing hormone stimulus. Corticotropin-releasing hormone is a peptide hormone involved in the stress response.

NR4A1, NR4A2, NR4A3

GO:0071377

BP

cellular response to glucagon stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucagon stimulus.

GNG7, ADCY3, ADCY9, ASS1, GCG, PRKAR1A, PRKAR2A, GNB3, PRKACA, PRKAR2B, PCK1, GNG4, ADCY7, GNG11, GNB1, GNB2, GNG5

GO:0071378

BP

cellular response to growth hormone stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth hormone stimulus. Growth hormone is a peptide hormone that binds to the growth hormone receptor and stimulates growth.

STAR

GO:0071379

BP

cellular response to prostaglandin stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin stimulus.

APOB, AKR1C3

GO:0071380

BP

cellular response to prostaglandin E stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin E stimulus.

TNFSF4, AKT1, PTGER4, PPARG, PTGER2, PRKAA2, GNB1, SFRP1

GO:0071383

BP

cellular response to steroid hormone stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus.

NPC1, URI1, NR3C1, ATP1A2, MGARP

GO:0071384

BP

cellular response to corticosteroid stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosteroid hormone stimulus. A corticosteroid is a steroid hormone that is produced in the adrenal cortex. Corticosteroids are involved in a wide range of physiologic systems such as stress response, immune response and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte levels, and behavior. They include glucocorticoids and mineralocorticoids.

AKR1C3

GO:0071385

BP

cellular response to glucocorticoid stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects.

ANXA1, EDN1, GSTP1, ZFP36, SSTR5, ZFP36L2, STC1, ZFP36L1, HEY1

GO:0071386

BP

cellular response to corticosterone stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosterone stimulus. Corticosterone is a 21 carbon steroid hormone of the corticosteroid type, produced in the cortex of the adrenal glands. In many species, corticosterone is the principal glucocorticoid, involved in regulation of fuel metabolism, immune reactions, and stress responses.

FOXO3, ATP2B1

GO:0071387

BP

cellular response to cortisol stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cortisol stimulus. Cortisol is the major natural glucocorticoid synthesized in the zona fasciculata of the adrenal cortex; it affects the metabolism of glucose, protein, and fats and has appreciable mineralocorticoid activity. It also regulates the immune system and affects many other functions.

KLF9

GO:0071389

BP

cellular response to mineralocorticoid stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mineralocorticoid stimulus. Mineralocorticoids are hormonal C21 corticosteroids synthesized from cholesterol and characterized by their similarity to aldosterone. Mineralocorticoids act primarily on water and electrolyte balance.

EDN1, GPER1

GO:0071391

BP

cellular response to estrogen stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by an estrogen, C18 steroid hormones that can stimulate the development of female sexual characteristics.

ESR1, SERPINB9, MDM2, SFRP1, WBP2

GO:0071392

BP

cellular response to estradiol stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen.

RAMP3, AIFM1, EGFR, ESR1, IL6, H2AFZ, ITGA2, SRD5A1, CCNA2, IL10, SSTR1, NRIP1, HSF1, HNRNPD, SFRP1, GPER1, PPARGC1A, RUVBL2, NCOA3

GO:0071394

BP

cellular response to testosterone stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a testosterone stimulus.

ROCK2, SRD5A1, ELK1, AACS

GO:0071395

BP

cellular response to jasmonic acid stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a jasmonic acid stimulus.

AKR1C3, AKR1C2, AKR1C1

GO:0071396

BP

cellular response to lipid

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus.

BAD

GO:0071397

BP

cellular response to cholesterol

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cholesterol stimulus.

LRP6, ABCA1, INHBA, GPLD1, HMGCS1, PTCH1, AACS

GO:0071398

BP

cellular response to fatty acid

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fatty acid stimulus.

LDLR, EDN1, XRCC5, CCNB1, NME1, CREB1, NME2, PTAFR, SREBF1, CPT1A, E2F1, PDK4, PID1, SMARCD1, NR1H4, OR51E2

GO:0071400

BP

cellular response to oleic acid

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oleic acid stimulus.

ASS1, DGAT2

GO:0071401

BP

cellular response to triglyceride

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triglyceride stimulus.

GPLD1

GO:0071403

BP

cellular response to high density lipoprotein particle stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a high density lipoprotein particle stimulus.

CCL2

GO:0071404

BP

cellular response to low-density lipoprotein particle stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a low-density lipoprotein particle stimulus.

NPC1, ITGB2, ITGB1, CD36, CD9, SYK, CD81

GO:0071407

BP

cellular response to organic cyclic compound

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.

AXIN1, SMAD9, PAK3, TGFB1, TNF, IL1B, CYP1A1, ALPL, HSP90AB1, LGALS1, GLI2, CCL3, BMP2, CCL2, CCL5, CCNB1, CEBPB, ITGA6, IGFBP5, AKT1, STAT3, CDKN1B, RAE1, TMF1, PAK2, IL18, CASP8, ANKRD1, CYP1B1, SMAD5, BTRC

GO:0071409

BP

cellular response to cycloheximide

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cycloheximide stimulus. Cycloheximide (actidione) is an antibiotic produced by some Streptomyces species which interferes with protein synthesis in eukaryotes.

KLF4, KLF2

GO:0071417

BP

cellular response to organonitrogen compound

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organonitrogen stimulus. An organonitrogen compound is formally a compound containing at least one carbon-nitrogen bond.

NR1H4

GO:0071418

BP

cellular response to amine stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amine stimulus. An amine is a compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups.

ASS1

GO:0071420

BP

cellular response to histamine

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histamine stimulus. Histamine, the biogenic amine 2-(1H-imidazol-4-yl)ethanamine, is involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter.

HRH1

GO:0071421

BP

manganese ion transmembrane transport

A process in which a manganese ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.

ZP3, SLC11A1, SLC11A2

GO:0071424

MF

rRNA (cytosine-N4-)-methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N4-methylcytosine.

METTL15

GO:0071425

BP

hematopoietic stem cell proliferation

The expansion of a hematopoietic stem cell population by cell division. A hematopoietic stem cell is a stem cell from which all cells of the lymphoid and myeloid lineages develop.

WNT5A, RUNX1, SART3, SHB, NKAP, WNT2B

GO:0071426

BP

ribonucleoprotein complex export from nucleus

The directed movement of a ribonucleoprotein complex from the nucleus to the cytoplasm.

NUP62, NUP62CL

GO:0071435

BP

potassium ion export

The directed movement of potassium ions out of a cell or organelle.

KCNH2, KCNIP2

GO:0071437

CC

invadopodium

A cell projection that emerges from the ECM-facing surface of a cell, is enriched in actin and associated cytoskeletal proteins, and displays localized proteolytic activity toward the substrate.

WASH1, FSCN1, RUFY3

GO:0071438

CC

invadopodium membrane

The portion of the plasma membrane surrounding an invadopodium.

ITGB1, ITGA3, DPP4, PLAUR

GO:0071439

CC

clathrin complex

A protein complex that consists of three clathrin heavy chains and three clathrin light chains, organized into a symmetrical three-legged structure called a triskelion. In clathrin-coated vesicles clathrin is the main component of the coat and forms a polymeric mechanical scaffold on the vesicle surface.

CLTA

GO:0071442

BP

positive regulation of histone H3-K14 acetylation

Any process that activates or increases the frequency, rate or extent of the addition of an acetyl group to histone H3 at position 14 of the histone.

WBP2, NAP1L2

GO:0071447

BP

cellular response to hydroperoxide

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroperoxide stimulus. Hydroperoxides are monosubstitution products of hydrogen peroxide, HOOH.

CD36, PRKCD, OXR1, TP53INP1

GO:0071449

BP

cellular response to lipid hydroperoxide

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid hydroperoxide stimulus. Lipid hydroperoxide is the highly reactive primary oxygenated products of polyunsaturated fatty acids.

MGST1

GO:0071451

BP

cellular response to superoxide

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a superoxide stimulus. Superoxide is the anion, oxygen-, formed by addition of one electron to dioxygen (O2) or any compound containing the superoxide anion.

GLRX2

GO:0071455

BP

cellular response to hyperoxia

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating increased oxygen tension.

FAS, PPARG, CAV1, FOXO1, DNMT3B

GO:0071456

BP

cellular response to hypoxia

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.

KCNK3, MDM4, FOXO3, BNIP3L, STC2, LMNA, S100B, TP53, EDN1, ICAM1, P4HB, HMOX1, BCL2, CCNB1, SLC2A4, VEGFA, CCNA2, MT3, AKT1, PTGS2, RORA, PCK1, IRAK1, STC1, NPEPPS, PTEN, GNB1, ADAM8, MDM2, E2F1, PPARD, ZFP36L1, BNIP3, EIF4EBP1, PMAIP1, ANKRD1, TWIST1, PTGIS, HIF1A, CPEB2, SIRT2, SFRP1, NDNF, MGARP, NDRG1, GATA6, BAD, FAM162A, ERO1A, SLC29A1, EPAS1, PINK1, HIPK2, RGCC, SUV39H2, FMN2, PPARGC1A, TRPC6, HYOU1, TBL2

GO:0071458

CC

integral component of cytoplasmic side of endoplasmic reticulum membrane

The component of the endoplasmic reticulum membrane consisting of the gene products that penetrate only the cytoplasmic side of the membrane.

PKD2, SPPL3, SPPL2A, HM13

GO:0071459

BP

protein localization to chromosome, centromeric region

Any process in which a protein is transported to, or maintained at, the centromeric region of a chromosome.

RB1, CENPA, GSG2

GO:0071460

BP

cellular response to cell-matrix adhesion

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of cell-matrix adhesion.

GSTP1, SKP2

GO:0071461

BP

cellular response to redox state

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating redox state. Redox state refers to the balance of oxidized versus reduced forms of electron donors and acceptors in an organelle, cell or organ; plastoquinone, glutathione (GSH/GSSG), and nicotinamide nucleotides (NAD+/NADH and NADP+/NADPH) are among the most important.

ARHGDIB

GO:0071464

BP

cellular response to hydrostatic pressure

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrostatic pressure stimulus. Hydrostatic pressure is the force acting on an object in a system where the fluid is at rest (as opposed to moving). The weight of the fluid above the object creates pressure on it.

PKD2

GO:0071466

BP

cellular response to xenobiotic stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a xenobiotic compound stimulus. Xenobiotic compounds are compounds foreign to living organisms.

RB1, MCM7, E2F1

GO:0071467

BP

cellular response to pH

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution.

GNA11, GPLD1

GO:0071468

BP

cellular response to acidic pH

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH < 7. pH is a measure of the acidity or basicity of an aqueous solution.

RAB11B, TRPV1, CHP1, IMPACT

GO:0071470

BP

cellular response to osmotic stress

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.

DDX3X, SLC2A4, RELB, PKD2, TRPV4

GO:0071472

BP

cellular response to salt stress

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.

CAPN3, ZFP36L1

GO:0071474

BP

cellular hyperosmotic response

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hyperosmotic environment, i.e. an environment with a higher concentration of solutes than the organism or cell.

ARHGEF2, ERRFI1

GO:0071475

BP

cellular hyperosmotic salinity response

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, an increase in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.

XRCC5

GO:0071476

BP

cellular hypotonic response

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hypotonic environment, i.e. an environment with a lower concentration of solutes than the organism or cell.

TSPO, MYLK, TRPV4, CAB39

GO:0071477

BP

cellular hypotonic salinity response

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.

TRPV4

GO:0071478

BP

cellular response to radiation

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation.

HSF1, ADIRF

GO:0071479

BP

cellular response to ionizing radiation

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ionizing radiation stimulus. Ionizing radiation is radiation with sufficient energy to remove electrons from atoms and may arise from spontaneous decay of unstable isotopes, resulting in alpha and beta particles and gamma rays. Ionizing radiation also includes X-rays.

SNAI2, RAD1, TGFB1, TP53, GADD45A, EEF1D, CDKN1A, BLM, RHOB, GRB2, RAD51, SPIDR, MAPK14, IFI16, SWI5, RAD9B, NET1, TANK, RAD51AP1, RAD9A, RHNO1, ECT2, INTS7

GO:0071480

BP

cellular response to gamma radiation

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gamma radiation stimulus. Gamma radiation is a form of electromagnetic radiation (EMR) or light emission of a specific frequency produced from sub-atomic particle interaction, such as electron-positron annihilation and radioactive decay. Gamma rays are generally characterized as EMR having the highest frequency and energy, and also the shortest wavelength, within the electromagnetic radiation spectrum.

KDM1A, CRYAB, XRCC5, H2AFX, EGR1, ELK1, YAP1, RAD51, TSPYL5, NOX4

GO:0071481

BP

cellular response to X-ray

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of X-ray radiation. An X-ray is a form of electromagnetic radiation with a wavelength in the range of 10 nanometers to 100 picometers (corresponding to frequencies in the range 30 PHz to 3 EHz).

XRCC5, HAMP, NIPBL, SFRP1, NUCKS1

GO:0071482

BP

cellular response to light stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light.

OPN1SW, OPN3

GO:0071492

BP

cellular response to UV-A

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-A radiation stimulus. UV-A radiation (UV-A light) spans the wavelengths 315 to 400 nm.

MME, PPID

GO:0071493

BP

cellular response to UV-B

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-B radiation stimulus. UV-B radiation (UV-B light) spans the wavelengths 280 to 315 nm.

MME, CDKN1A, HYAL2, STK11

GO:0071494

BP

cellular response to UV-C

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-C radiation stimulus. UV-C radiation (UV-C light) spans the wavelengths 100 to 280 nm.

MDM2, IMPACT, POLH

GO:0071498

BP

cellular response to fluid shear stress

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluid shear stress stimulus. Fluid shear stress is the force acting on an object in a system where the fluid is moving across a solid surface.

HDAC3, MTSS1, CA2, PTGS2, TFPI2, MEF2C, PKD2, HAS2

GO:0071499

BP

cellular response to laminar fluid shear stress

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a laminar fluid shear stress stimulus. Laminar fluid flow is the force acting on an object in a system where the fluid is moving across a solid surface in parallel layers.

KLF4, ASS1, SREBF2, MAP2K5, MAPK7, KLF2

GO:0071502

BP

cellular response to temperature stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus.

HTR2B, TRPV1

GO:0071504

BP

cellular response to heparin

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heparin stimulus.

SLIT2, EGR1, SOX9, SFRP1

GO:0071506

BP

cellular response to mycophenolic acid

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mycophenolic acid stimulus.

PDGFB, EGR1

GO:0071514

BP

genetic imprinting

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules by a mechanism that is mediated by DNA, is mitotically or meiotically heritable, or is stably self-propagated in the cytoplasm of a resting cell, and does not entail a change in DNA sequence.

CDKN1C, GNAS, GNAS

GO:0071526

BP

semaphorin-plexin signaling pathway

A series of molecular signals generated as a consequence of a semaphorin receptor (composed of a plexin and a neurophilin) binding to a semaphorin ligand.

NRP1, PLXNB2, SEMA3E, PLXNA2, FARP2, SEMA3D, MET, FLNA, PLXNA3, ARHGDIA, RAC1, SEMA3B, SEMA5A, SEMA3A, SEMA6D, SEMA3C, SEMA6A, SEMA4A, SEMA6B, PLXND1

GO:0071529

BP

cementum mineralization

The process in which calcium salts, mainly carbonated hydroxyapatite, are deposited into the initial acellular cementum.

ALPL

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