GO:0070192

BP

chromosome organization involved in meiotic cell cycle

A process of chromosome organization that is involved in a meiotic cell cycle.

RAD51C, RAD51, RAD50

GO:0070193

BP

synaptonemal complex organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synaptonemal complex. A synaptonemal complex is a proteinaceous scaffold formed between homologous chromosomes during meiosis.

UBE2B

GO:0070194

BP

synaptonemal complex disassembly

The controlled breakdown of a synaptonemal complex.

PLK1

GO:0070195

CC

growth hormone receptor complex

A receptor complex that consists of two identical subunits and binds growth hormone.

GHR

GO:0070198

BP

protein localization to chromosome, telomeric region

Any process in which a protein is transported to, or maintained at, the telomeric region of a chromosome.

TNKS, ATRX, ACD, TNKS2

GO:0070200

BP

establishment of protein localization to telomere

The directed movement of a protein to a specific location in the telomeric region of a chromosome.

BRCA2, ACD, NABP2, POT1

GO:0070201

BP

regulation of establishment of protein localization

Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location.

WHSC1, HDAC6

GO:0070202

BP

regulation of establishment of protein localization to chromosome

Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location on a chromosome.

SPIDR

GO:0070206

BP

protein trimerization

The formation of a protein trimer, a macromolecular structure consisting of three noncovalently associated identical or nonidentical subunits.

TRIM22, C1QTNF3, TRIM34, TRIM6, TRIM4

GO:0070207

BP

protein homotrimerization

The formation of a protein homotrimer, a macromolecular structure consisting of three noncovalently associated identical subunits.

MGST1, SKI, MIF, PNPT1, SIGMAR1, ATXN10

GO:0070208

BP

protein heterotrimerization

The formation of a protein heterotrimer, a macromolecular structure consisting of three noncovalently associated subunits, of which not all are identical.

WIZ, COL1A1, COL1A2, COL6A1, COL6A2, NUP62, GNB1, ADIPOQ, NUP58, C1QTNF1

GO:0070212

BP

protein poly-ADP-ribosylation

The transfer of multiple ADP-ribose residues from NAD to a protein amino acid, forming a poly(ADP-ribose) chain.

TNKS, PARP1

GO:0070213

BP

protein auto-ADP-ribosylation

The ADP-ribosylation by a protein of one or more of its own amino acid residues, or residues on an identical protein.

TNKS, TNKS2

GO:0070221

BP

sulfide oxidation, using sulfide:quinone oxidoreductase

A sulfide oxidation process that proceeds via the reaction catalyzed by sulfide:quinone oxidoreductase.

ETHE1, SUOX, SLC25A10

GO:0070230

BP

positive regulation of lymphocyte apoptotic process

Any process that activates or increases the frequency, rate or extent of lymphocyte death by apoptotic process.

FAS

GO:0070231

BP

T cell apoptotic process

Any apoptotic process in a T cell, a type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex.

BCL10, RIPK1

GO:0070232

BP

regulation of T cell apoptotic process

Any process that modulates the occurrence or rate of T cell death by apoptotic process.

LGALS3, JAK3

GO:0070233

BP

negative regulation of T cell apoptotic process

Any process that stops, prevents, or reduces the frequency, rate or extent of T cell death by apoptotic process.

CCL5, CD27, PRKCQ, DOCK8, SLC46A2

GO:0070234

BP

positive regulation of T cell apoptotic process

Any process that activates or increases the frequency, rate or extent of T cell death by apoptotic process.

CCL5, LGALS13, PRELID1

GO:0070236

BP

negative regulation of activation-induced cell death of T cells

Any process that stops, prevents, or reduces the frequency, rate or extent of activation-induced cell death of T cells.

FADD, TSC22D3, GPAM

GO:0070237

BP

positive regulation of activation-induced cell death of T cells

Any process that activates or increases the frequency, rate or extent of activation-induced cell death of T cells.

TGFB2

GO:0070242

BP

thymocyte apoptotic process

Any apoptotic process in a thymocyte, an immature T cell located in the thymus.

DFFA, BCL2L11, GLI3, BAX

GO:0070244

BP

negative regulation of thymocyte apoptotic process

Any process that stops, prevents, or reduces the frequency, rate or extent of thymocyte death by apoptotic process.

ADA, BMP4, RAG1, EFNA1, JAK3, HIF1A

GO:0070245

BP

positive regulation of thymocyte apoptotic process

Any process that activates or increases the frequency, rate or extent of thymocyte death by apoptotic process.

TP53, WNT5A, ADAM8

GO:0070251

MF

pristanate-CoA ligase activity

Catalysis of the reaction: ATP + pristanate + CoA = AMP + diphosphate + pristanoyl-CoA.

SLC27A2

GO:0070252

BP

actin-mediated cell contraction

The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of all or part of the cell body.

EMP2, PARVA

GO:0070253

BP

somatostatin secretion

The regulated release of somatostatin from secretory granules in the D cells of the pancreas.

CARTPT

GO:0070256

BP

negative regulation of mucus secretion

Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of mucus from a cell or a tissue.

ADA, ADORA1

GO:0070257

BP

positive regulation of mucus secretion

Any process that activates or increases the frequency, rate or extent of the regulated release of mucus from a cell or a tissue.

SYTL2

GO:0070260

MF

5'-tyrosyl-DNA phosphodiesterase activity

Catalysis of the hydrolysis of 5'-phosphotyrosyl groups formed as covalent intermediates (in DNA backbone breakage) between DNA topoisomerase II and DNA.

TDP2

GO:0070262

BP

peptidyl-serine dephosphorylation

The removal of phosphoric residues from peptidyl-O-phospho-L-serine to form peptidyl-serine.

PPP1R15A, PPP2R1A

GO:0070266

BP

necroptotic process

A programmed necrotic cell death process which begins when a cell receives a signal (e.g. a ligand binding to a death receptor or to a Toll-like receptor), and proceeds through a series of biochemical events (signaling pathways), characterized by activation of receptor-interacting serine/threonine-protein kinase 1 and/or 3 (RIPK1/3, also called RIP1/3) and by critical dependence on mixed lineage kinase domain-like (MLKL), and which typically lead to common morphological features of necrotic cell death. The process ends when the cell has died. The process is divided into a signaling phase, and an execution phase, which is triggered by the former.

TLR4, TLR3, CD14, PPIF, RIPK1, TRPM7, CYLD

GO:0070268

BP

cornification

A type of programmed cell death that occurs in the epidermis, morphologically and biochemically distinct from apoptosis. It leads to the formation of corneocytes, i.e. dead keratinocytes containing an amalgam of specific proteins (e.g., keratin, loricrin, SPR and involucrin) and lipids (e.g., fatty acids and ceramides), which are necessary for the function of the cornified skin layer (mechanical resistance, elasticity, water repellence and structural stability).

CYP26B1

GO:0070269

BP

pyroptosis

A caspase-1-dependent cell death subroutine that is associated with the generation of pyrogenic mediators such as IL-1beta and IL-18.

CASP1

GO:0070273

MF

phosphatidylinositol-4-phosphate binding

Interacting selectively and non-covalently with phosphatidylinositol-4-phosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 4' position.

SH3PXD2B, SNX3, OSBP, ARFIP1, OSBPL8, PLEKHA5, SNX24

GO:0070274

CC

RES complex

A protein complex that is required for efficient splicing, and prevents leakage of unspliced pre-mRNAs from the nucleus (named for pre-mRNA REtention and Splicing). In Saccharomyces, the complex consists of Ist3p, Bud13p, and Pml1p.

BUD13, RBMX2

GO:0070278

BP

extracellular matrix constituent secretion

The controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell.

CTGF, CREB3L1

GO:0070286

BP

axonemal dynein complex assembly

The aggregation, arrangement and bonding together of a set of components to form an axonemal dynein complex, a dynein complex found in eukaryotic cilia and flagella, in which the motor domain heads interact with adjacent microtubules to generate a sliding force which is converted to a bending motion.

CCDC103, DRC1, DNAAF2

GO:0070290

MF

N-acylphosphatidylethanolamine-specific phospholipase D activity

Catalysis of the release of N-acylethanolamine from N-acyl-phosphatidylethanolamine (NAPE) to generate N-acylethanolamine (NAE).

PLD1, NAPEPLD

GO:0070292

BP

N-acylphosphatidylethanolamine metabolic process

The chemical reactions and pathways involving N-acylphosphatidylethanolamines. An N-acylphosphatidylethanolamine is a phosphatidylethanolamine substituted at nitrogen by an acyl group.

HRASLS5

GO:0070293

BP

renal absorption

A renal system process in which water, ions, glucose and proteins are taken up from the collecting ducts, glomerulus and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures (e.g. protein absorption is observed in nephrocytes in Drosophila, see PMID:23264686).

AKR1C3, HBB

GO:0070294

BP

renal sodium ion absorption

A renal system process in which sodium ions are taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures.

KLHL3, MAGED2

GO:0070295

BP

renal water absorption

A renal system process in which water is taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures.

HYAL2, AQP3, HAS2

GO:0070296

BP

sarcoplasmic reticulum calcium ion transport

The directed movement of calcium ions (Ca2+) into, out of or within the sarcoplasmic reticulum.

ATP2A2, ANK2, RYR2

GO:0070300

MF

phosphatidic acid binding

Interacting selectively and non-covalently with phosphatidic acid, any of a class of glycerol phosphate in which both the remaining hydroxyl groups of the glycerol moiety are esterified with fatty acids.

PLCD1, UQCC3, COMMD1, RAPGEF6, MAPKAP1, ATP13A2, MARK1, PITPNC1

GO:0070301

BP

cellular response to hydrogen peroxide

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.

KLF4, AIFM1, CST3, ANXA1, IL6, CDK1, PCNA, ETS1, AKR1B1, TNFAIP3, PPIF, RHOB, HSF1, MDM2, RELA, PRKCD, FOXO1, BNIP3, MAPK7, EZH2, FXN, CYP1B1, SETX, NET1, HDAC2, MAP3K5, PDGFD, ECT2, ZNF277, OSER1, IMPACT, HDAC6, ZNF580, TRPC6, KLF2

GO:0070304

BP

positive regulation of stress-activated protein kinase signaling cascade

Any process that activates or increases the frequency, rate or extent of signaling via the stress-activated protein kinase signaling cascade.

LYN

GO:0070306

BP

lens fiber cell differentiation

The process in which a relatively unspecialized cell acquires specialized features of a lens fiber cell, any of the elongated, tightly packed cells that make up the bulk of the mature lens in the camera-type eye. The cytoplasm of a lens fiber cell is devoid of most intracellular organelles including the cell nucleus, and contains primarily crystallins, a group of water-soluble proteins expressed in vary large quantities.

MAF, TGFB1, SKIL, NF2, SMAD3, KDM5B, FZR1, SLC7A11

GO:0070307

BP

lens fiber cell development

The process whose specific outcome is the progression of a lens fiber cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a lens fiber cell fate. A lens fiber cell is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye.

VIM, TMOD1, FRS2, WNT5B

GO:0070309

BP

lens fiber cell morphogenesis

The process in which the structures of a lens fiber cell are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a lens fiber cell. A lens fiber cell is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye.

PROX1

GO:0070314

BP

G1 to G0 transition

A cell cycle arrest process that results in arrest during G1 phase, whereupon the cell enters a specialized resting state known as G0 or quiescence.

CYP27B1, PHGDH, HRSP12, EZH2

GO:0070315

BP

G1 to G0 transition involved in cell differentiation

A cell cycle arrest process that results in arrest during G1 phase, whereupon the cell enters G0 phase, in the context of cell differentiation.

CAPN3, ZNF503

GO:0070317

BP

negative regulation of G0 to G1 transition

A cell cycle process that stops, prevents, or reduces the rate or extent of the transition from the G0 quiescent state to the G1 phase.

FOXO4, PPP2R5B

GO:0070318

BP

positive regulation of G0 to G1 transition

A cell cycle process that activates or increases the rate or extent of the transition from the G0 quiescent state to the G1 phase.

SOX15, CTGF, RHNO1

GO:0070320

MF

inward rectifier potassium channel inhibitor activity

Stops, prevents, or reduces the activity of an inwardly rectifying potassium channel.

CAV1

GO:0070324

MF

thyroid hormone binding

Interacting selectively and non-covalently with thyroxine (T4) or triiodothyronine (T3), tyrosine-based hormones produced by the thyroid gland.

TTR, CTSH, THRA, ALDH1A3

GO:0070325

MF

lipoprotein particle receptor binding

Interacting selectively and non-covalently with a lipoprotein particle receptor.

APOA5

GO:0070326

MF

very-low-density lipoprotein particle receptor binding

Interacting selectively and non-covalently with a very-low-density lipoprotein receptor.

APOE, LRPAP1, PCSK9

GO:0070327

BP

thyroid hormone transport

The directed movement of thyroid hormone into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

SLC16A10

GO:0070328

BP

triglyceride homeostasis

Any process involved in the maintenance of an internal steady state of triglyceride within an organism or cell.

APOA1, APOE, APOC3, LPL, RORA, SESN2, NR1H3, IL18, APOA5, SCARB1

GO:0070330

MF

aromatase activity

Catalysis of the reduction of an aliphatic ring to yield an aromatic ring.

CYP1A1, CYP3A4, CYP2D6, CYP19A1, CYP3A5, CYP3A7, CYP1B1, CYP2U1, CYP3A43

GO:0070335

MF

aspartate binding

Interacting selectively and non-covalently with aspartate, the alpha-amino-acid anion of 2-aminobutanedioic acid that has formula C4H5NO4.

CAD

GO:0070336

MF

flap-structured DNA binding

Interacting selectively and non-covalently with a flap structure in DNA. A DNA flap structure is one in which a single-stranded length of DNA or RNA protrudes from a double-stranded DNA molecule.

FAN1

GO:0070345

BP

negative regulation of fat cell proliferation

Any process that stops or decreases the rate or extent of fat cell proliferation.

E2F1, TFDP1

GO:0070346

BP

positive regulation of fat cell proliferation

Any process that activates or increases the rate or extent of fat cell proliferation.

PID1

GO:0070350

BP

regulation of white fat cell proliferation

Any process that modulates the frequency, rate or extent of white fat cell proliferation.

FTO

GO:0070358

BP

actin polymerization-dependent cell motility

A process involved in the controlled movement of a bacterial cell powered by the continuous polymerization of actin at one pole of the cell.

EPS8, JMY

GO:0070363

MF

mitochondrial light strand promoter sense binding

Interacting selectively and non-covalently with the sense strand of the light strand promoter, a promoter located on the light, or cytosine-rich, strand of mitochondrial DNA.

TFAM

GO:0070365

BP

hepatocyte differentiation

The process in which a relatively unspecialized cell acquires the specialized features of a hepatocyte. A hepatocyte is specialized epithelial cell that is organized into interconnected plates called lobules, and is the main structural component of the liver.

E2F8, ANXA1, CYP1A1, ITGA2, HHEX, PROX1

GO:0070369

CC

beta-catenin-TCF7L2 complex

A protein complex that contains beta-catenin and TCF7L2 (TCF4), binds to the TCF DNA motif within a promoter element, and is involved in the regulation of WNT target gene transcription.

CTNNB1, TCF7L2

GO:0070370

BP

cellular heat acclimation

Any process that increases heat tolerance of a cell in response to high temperatures.

HSPA1A, HSPA1B

GO:0070371

BP

ERK1 and ERK2 cascade

An intracellular protein kinase cascade containing at least ERK1 or ERK2 (MAPKs), a MEK (a MAPKK) and a MAP3K. The cascade can also contain two additional tiers: the upstream MAP4K and the downstream MAP Kinase-activated kinase (MAPKAPK). The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell.

TNFSF11, AGT, IGF1, ITGAV, CTSH, MT3, MAPK3, MAPK1, OXTR, PTGER4, MAP2K2, HTR2B, ZFP36L2, SOX9, MAP2K1, ZFP36L1, IQGAP3

GO:0070372

BP

regulation of ERK1 and ERK2 cascade

Any process that modulates the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.

CYR61, FN1, ERBB2, LYN, GSTP1, RRAS, FGFR2, SYK, EPHB1, TIAM1, NEK10, FRS2, FAM83D

GO:0070373

BP

negative regulation of ERK1 and ERK2 cascade

Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.

TLR4, ITGB1BP1, KLF4, SPRY2, SPRY1, LYN, GSTP1, LIF, EZR, PTPN2, ATF3, FBLN1, DUSP1, GBP1, PHB, TIMP3, CSK, DUSP3, SYNJ2BP, PTEN, DLG1, SMAD4, RAPGEF1, EIF3A, ADIPOQ, DUSP6, CNKSR3, FLCN, RANBP9, GPER1, DUSP26, SPRY4, ERRFI1, NDRG2

GO:0070374

BP

positive regulation of ERK1 and ERK2 cascade

Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.

TLR4, NRP1, RIPK2, SPRY2, SEMA7A, FGF18, FGF19, EGFR, PDGFB, GCG, TNF, FGA, FGB, FGG, HMGCR, PDGFA, CD74, NTRK1, IL6, ICAM1, JUN, CSF1R, FGF2, HMGB1, PDGFRB, CCL3, BMP2, BMP4, CCL4, CCL2, CCL5, MIF, DRD2, PLA2G2A, ALOX15, CD44, NQO2, PDGFRA, CD36, PRKCA, C5AR1, FGFR2, FSHR, F2R, MT3, MAPK3, HTR2C, CTGF, S100A7, GPR183, PHB, ADRA1A, FLT4, CHI3L1, MAP2K2, PLA2G5, HTR2B, F2RL1, TIRAP, PTEN, RAP1A, CCL20, CCL8, MAP2K1, TEK, PTPN11, CAMK2D, GAS6, ERBB4, ANGPT1, NPY5R, FAM150B, DSTYK, GCNT2, BMPER, PRKCDBP, GPER1, PHB2, CIB1, PRKD2, PDGFD, GLIPR2, GAREM1, TRPV4, NOX4, PDGFC, DNAJC27, NDRG4, PYCARD, PTPN22

GO:0070375

BP

ERK5 cascade

An intracellular protein kinase cascade containing at least ERK5 (also called BMK1; a MAPK), a MEK (a MAPKK) and a MAP3K. The cascade can also contain two additional tiers: the upstream MAP4K and the downstream MAP Kinase-activated kinase (MAPKAPK). The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell.

MEF2A, MAP2K5

GO:0070377

BP

negative regulation of ERK5 cascade

Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the ERK5 cascade.

MAPK7

GO:0070378

BP

positive regulation of ERK5 cascade

Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK5 cascade.

FAM150B

GO:0070382

CC

exocytic vesicle

A transport vesicle that mediates transport from an intracellular compartment to the plasma membrane, and fuses with the plasma membrane to release various cargo molecules, such as proteins or hormones, by exocytosis.

IGF1, RAB27A, DPYSL3, SYTL5, SYTL4, SYTL2

GO:0070383

BP

DNA cytosine deamination

The removal of an amino group from a cytosine residue in DNA, forming a uracil residue.

APOBEC3G

GO:0070384

BP

Harderian gland development

The process whose specific outcome is the progression of the Harderian gland over time, from its formation to the mature structure. The Harderian gland is an anterior orbital structure usually associated with the nictitating membrane, and produces and secretes a variety of substances to the eye, depending upon the species.

SOX9

GO:0070389

BP

chaperone cofactor-dependent protein refolding

The process of assisting in the restoration of the biological activity of an unfolded or misfolded protein, which is dependent on additional protein cofactors. This process occurs over one or several cycles of nucleotide hydrolysis-dependent binding and release.

DNAJB1, PTGES3, DNAJC7

GO:0070390

CC

transcription export complex 2

A protein complex that couples SAGA-dependent gene expression to mRNA export at the inner side of the nuclear pore complex (NPC). The TREX-2 complex is tethered to the inner side of the NPC via the nucleoporins Nup1 and Nup60; in S. cerevisiae it contains Sac3p, Thp1p, Sus1p and Cdc31p.

ENY2

GO:0070401

MF

NADP+ binding

Interacting selectively and non-covalently with the oxidized form, NADP+, of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions.

GMDS

GO:0070402

MF

NADPH binding

Interacting selectively and non-covalently with the reduced form, NADPH, of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions.

DHFR, HMGCR, QDPR, SRD5A1, FASN, CRYZ, DECR1, GRHPR

GO:0070403

MF

NAD+ binding

Interacting selectively and non-covalently with the oxidized form, NAD, of nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions.

HPGD, ALDH1A3, HADH, SIRT2, UXS1, CRYL1

GO:0070404

MF

NADH binding

Interacting selectively and non-covalently with the reduced form, NADH, of nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions.

QDPR

GO:0070410

MF

co-SMAD binding

Interacting selectively and non-covalently with a common mediator SMAD signaling protein.

SMAD6, GATA4, SMAD3, SMAD2, SMAD1, CITED1, TRIM33

GO:0070411

MF

I-SMAD binding

Interacting selectively and non-covalently with an inhibitory SMAD signaling protein.

SMAD7, AXIN1, TGFB1I1, SMAD6, CTNNB1, TGFBR1, SMAD4, SMAD2, SMAD1

GO:0070412

MF

R-SMAD binding

Interacting selectively and non-covalently with a receptor-regulated SMAD signaling protein.

SMAD6, FOS, JUN, PARP1, SMAD3, SMAD4, ANKRD1, SMAD2, ZC3H3, PMEPA1, RGCC, TRIM33

GO:0070417

BP

cellular response to cold

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.

FOXO1, DNAJC3, EIF2AK4

GO:0070419

CC

nonhomologous end joining complex

A protein complex that plays a role in DNA double-strand break repair via nonhomologous end joining. Such complexes typically contain a specialized DNA ligase (e.g. Lig4 in eukaryotes) and one or more proteins that bind to DNA ends.

XRCC5, PRKDC, XRCC4, DCLRE1C

GO:0070423

BP

nucleotide-binding oligomerization domain containing signaling pathway

Any series of molecular signals generated as a consequence of binding to a nucleotide-binding oligomerization domain containing (NOD) protein.

IRAK2, MAP3K7, RIPK2, UBC, TNFAIP3, IRAK1, MAP2K6, RPS27A, UBA52, UBE2V1, CASP8, TAB1, TAB3, ITCH, CYLD

GO:0070424

BP

regulation of nucleotide-binding oligomerization domain containing signaling pathway

Any process that modulates the frequency, rate, or extent of a nucleotide-binding oligomerization domain containing (NOD) pathway.

XIAP, BIRC3

GO:0070427

BP

nucleotide-binding oligomerization domain containing 1 signaling pathway

Any series of molecular signals generated as a consequence of binding to nucleotide-binding oligomerization domain containing 1 (NOD1).

RIPK2

GO:0070429

BP

negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway

Any process that stops, prevents, or reduces the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 1 (NOD1) pathway.

TNFAIP3

GO:0070430

BP

positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway

Any process that activates or increases the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 1 (NOD1) pathway.

TLR4

GO:0070431

BP

nucleotide-binding oligomerization domain containing 2 signaling pathway

Any series of molecular signals generated as a consequence of binding to nucleotide-binding oligomerization domain containing 2 (NOD2).

RIPK2, RELA

GO:0070433

BP

negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway

Any process that stops, prevents, or reduces the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 2 (NOD2) pathway.

TNFAIP3, PTPN22

GO:0070434

BP

positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway

Any process that activates or increases the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 2 (NOD2) pathway.

TLR4, HSPA1A, HSPA1B