| GO ID | Ontology | GO Term | Term Definition |
Proteins |
GO:0061113 | BP | pancreas morphogenesis | Morphogenesis of the pancreas. Morphogenesis is the process in which anatomical structures are generated and organized. |
NR5A2 |
GO:0061114 | BP | branching involved in pancreas morphogenesis | The process in which the branches of the pancreas are generated and organized. |
PROX1 |
GO:0061133 | MF | endopeptidase activator activity | Increases the activity of an endopeptidase, any enzyme that hydrolyzes nonterminal peptide bonds in polypeptides. |
PSME3, ADRM1 |
GO:0061136 | BP | regulation of proteasomal protein catabolic process | Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome. |
GPX1, PRKACA, PSME3, TMF1, PKD1, RHBDF1, PINK1, NUDT15, BTRC, UCHL5 |
GO:0061138 | BP | morphogenesis of a branching epithelium | The process in which the anatomical structures of a branched epithelium are generated and organized. |
SOX9, SOX8 |
GO:0061141 | BP | lung ciliated cell differentiation | The process in which a relatively unspecialized cell acquires specialized features of a lung ciliated cell. A lung ciliated cell is a specialized lung epithelial cell that contains cilia for moving substances released from lung secretory cells. |
NFIB |
GO:0061145 | BP | lung smooth muscle development | The process whose specific outcome is the progression of smooth muscle in the lung over time, from its formation to the mature structure. |
SOX9 |
GO:0061149 | BP | BMP signaling pathway involved in ureter morphogenesis | A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the shaping of the ureter. The ureter is a tube that extends from the kidney to the bladder. |
BMP4 |
GO:0061151 | BP | BMP signaling pathway involved in renal system segmentation | A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the segmentation of the renal system. |
BMP4 |
GO:0061154 | BP | endothelial tube morphogenesis | The process in which the anatomical structures of a tube are generated and organized from an endothelium. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells. |
CTNNB1, RHOB, CCM2, PRKD2 |
GO:0061155 | BP | pulmonary artery endothelial tube morphogenesis | The process in which the anatomical structures of a tube are generated and organized from the pulmonary artery endothelium. An pulmonary artery endothelium is an epithelium that lines the pulmonary artery. |
BMP4 |
GO:0061156 | BP | pulmonary artery morphogenesis | The process in which the anatomical structures of the pulmonary artery are generated and organized. The pulmonary artery is the artery that carries blood from the heart to the lungs. |
JAG1 |
GO:0061157 | BP | mRNA destabilization | Any process that decreases the stability of an mRNA molecule, making it more vulnerable to degradative processes. Messenger RNA is the intermediate molecule between DNA and protein. It includes UTR and coding sequences. It does not contain introns. |
HNRNPR, PUM1, MEX3D, METTL14 |
GO:0061158 | BP | 3'-UTR-mediated mRNA destabilization | An mRNA destabilization process in which one or more RNA-binding proteins associate with the 3'-untranslated region (UTR) of an mRNA. |
ZC3H12D, ZFP36, ZFP36L2, ZFP36L1, HNRNPD, CPEB3, KHSRP, QKI |
GO:0061162 | BP | establishment of monopolar cell polarity | The specification and formation of monopolar intracellular organization or cell growth patterns. Monopolar cell organization is directional organization along an axis. |
MAP1B, GBF1 |
GO:0061178 | BP | regulation of insulin secretion involved in cellular response to glucose stimulus | Any process that modulates the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose. |
LRP5, NR1D1, EFNA5, EPHA5, CDK16, TIAM1, NR1H4, SYBU, NRXN1 |
GO:0061179 | BP | negative regulation of insulin secretion involved in cellular response to glucose stimulus | Any process that decreases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose. |
HMGCR, UCP2, NDUFAF2, ENY2 |
GO:0061180 | BP | mammary gland epithelium development | The process whose specific outcome is the progression of the mammary gland epithelium over time, from its formation to the mature structure. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk. |
JAK2, WNT2, WNT3 |
GO:0061182 | BP | negative regulation of chondrocyte development | Any process that decreases the rate, frequency, or extent of the process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate. |
FAM101A, FAM101B |
GO:0061198 | BP | fungiform papilla formation | The developmental process pertaining to the initial formation of a spongiform papilla from unspecified parts. The fungiform papilla is a mushroom-shaped papilla of the tongue. |
CTNNB1, HDAC1, HDAC2 |
GO:0061202 | CC | clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane | The lipid bilayer surrounding a clathrin-sculpted gamma-aminobutyric acid transport vesicle. |
SYT1, VAMP2 |
GO:0061290 | BP | canonical Wnt signaling pathway involved in metanephric kidney development | The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contribute to the progression of the metanephric kidney over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes. |
LGR4 |
GO:0061298 | BP | retina vasculature development in camera-type eye | The process whose specific outcome is the progression of the vasculature of the retina over time, from its formation to the mature structure. |
PDGFRB, PDGFRA, ACVR2B, BMPR2, HIF1A |
GO:0061299 | BP | retina vasculature morphogenesis in camera-type eye | The process in which the vasculature of the retina is generated and organized. |
NRP1, NDP, RHOJ, FZD4 |
GO:0061301 | BP | cerebellum vasculature morphogenesis | The process in which the vasculature of the cerebellum is generated and organized. |
FZD4 |
GO:0061302 | BP | smooth muscle cell-matrix adhesion | The binding of a smooth muscle cell to the extracellular matrix via adhesion molecules. |
VTN, DDR1 |
GO:0061303 | BP | cornea development in camera-type eye | The progression of the cornea over time, from its formation to the mature structure. The cornea is the transparent structure that covers the anterior of the eye. |
WNT2B, WNT6 |
GO:0061304 | BP | retinal blood vessel morphogenesis | The process whose specific outcome is the progression of a blood vessel of the retina over time, from its formation to the mature structure. |
LRP5, CYP1B1, FZD4 |
GO:0061308 | BP | cardiac neural crest cell development involved in heart development | The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the development of the heart. |
MAPK3, MAPK1 |
GO:0061309 | BP | cardiac neural crest cell development involved in outflow tract morphogenesis | The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the shaping of the outflow tract. |
JAG1, HES1 |
GO:0061312 | BP | BMP signaling pathway involved in heart development | A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the progression of the heart over time. |
BMP4, BMPR1A, ACVR1 |
GO:0061314 | BP | Notch signaling involved in heart development | The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell and contributing to the progression of the heart over time. |
NOTCH1, JAG1, NOTCH2, DLL4, HEY1 |
GO:0061324 | BP | canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation | The canonical Wnt signaling pathway that contributes to the modulation of the expansion of a population of cardiac outflow tract cells. |
CTNNB1 |
GO:0061325 | BP | cell proliferation involved in outflow tract morphogenesis | The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the outflow tract. |
PITX2 |
GO:0061333 | BP | renal tubule morphogenesis | The process in which the renal tubule is generated by specification of cell fate, through the maintenance of cell polarity, regulated cell proliferation and morphogenetic cell rearrangements, shape changes and growth. A renal tubule is a tube that filters, re-absorbs and secretes substances to rid an organism of waste and to play a role in fluid homeostasis. |
MTSS1, MEF2C, PKD2 |
GO:0061337 | BP | cardiac conduction | Transfer of an organized electrical impulse across the heart to coordinate the contraction of cardiac muscles. The process begins with generation of an action potential (in the sinoatrial node (SA) in humans) and ends with a change in the rate, frequency, or extent of the contraction of the heart muscles. |
KCNK1, KCNK3, CACNB3, CACNA2D1, MEF2A, KCNH2, CACNA1C, KCNJ12, TRPM4, CACNG8, CACNG6, SPTBN4, KCNIP2, KCNK6 |
GO:0061343 | BP | cell adhesion involved in heart morphogenesis | The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules that contributes to the shaping of the heart. |
FLRT2 |
GO:0061347 | BP | planar cell polarity pathway involved in outflow tract morphogenesis | The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the outflow tract. |
WNT5A |
GO:0061348 | BP | planar cell polarity pathway involved in ventricular septum morphogenesis | The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the ventricular septum. |
WNT5A |
GO:0061349 | BP | planar cell polarity pathway involved in cardiac right atrium morphogenesis | The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the cardiac right atrium. |
WNT5A |
GO:0061350 | BP | planar cell polarity pathway involved in cardiac muscle tissue morphogenesis | The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the cardiac muscle tissue. |
WNT5A |
GO:0061351 | BP | neural precursor cell proliferation | The multiplication or reproduction of neural precursor cells, resulting in the expansion of a cell population. A neural precursor cell is either a nervous system stem cell or a nervous system progenitor cell. |
EPHB1, MELK, DBN1, ORC3 |
GO:0061354 | BP | planar cell polarity pathway involved in pericardium morphogenesis | The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the pericardium. |
WNT5A |
GO:0061355 | BP | Wnt protein secretion | The controlled release of a Wnt protein from a cell. |
WLS |
GO:0061357 | BP | positive regulation of Wnt protein secretion | Any process that activates or increases the frequency, rate or extent of the controlled release of a Wnt protein from a cell. |
WLS, VPS35 |
GO:0061364 | BP | apoptotic process involved in luteolysis | The apoptotic process that contributes to luteolysis. |
SLIT2, ROBO2 |
GO:0061368 | BP | behavioral response to formalin induced pain | Any process that results in a change in the behaviour of an organism as a result of a formalin pain stimulus. |
NTRK1 |
GO:0061370 | BP | testosterone biosynthetic process | The chemical reactions and pathways resulting in the formation of testosterone, an androgen having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4 C-5. |
HSD17B1, AKR1C3, STAR |
GO:0061383 | BP | trabecula morphogenesis | The process of shaping a trabecula in an organ. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue. |
RHOA |
GO:0061384 | BP | heart trabecula morphogenesis | The process of shaping a trabecula in the heart. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue. |
S1PR1, NOTCH1, TGFBR3, SOS1 |
GO:0061386 | BP | closure of optic fissure | The closure of the temporary ventral gap in the optic cup that contributes to its shaping. |
PHACTR4 |
GO:0061394 | BP | regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance | Modulation of the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of an arsenic stimulus from compounds containing arsenic, including arsenates, arsenites, and arsenides. |
ATF3 |
GO:0061395 | BP | positive regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance | Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of an arsenic stimulus from compounds containing arsenic, including arsenates, arsenites, and arsenides. |
ATF4 |
GO:0061402 | BP | positive regulation of transcription from RNA polymerase II promoter in response to acidic pH | Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a pH stimulus with pH < 7. |
PCK1 |
GO:0061418 | BP | regulation of transcription from RNA polymerase II promoter in response to hypoxia | Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hypoxia stimulus. |
BACH1, UBC, VEGFA, EGR1, ARNT, UBE2D3, RBX1, RPS27A, UBA52, EP300, CUL2, TCEB1, TCEB2, HIF1A, CREBBP, EPAS1, EGLN3, HIF3A |
GO:0061419 | BP | positive regulation of transcription from RNA polymerase II promoter in response to hypoxia | Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hypoxia stimulus. |
VEGFA, NOTCH1, HIF1A |
GO:0061428 | BP | negative regulation of transcription from RNA polymerase II promoter in response to hypoxia | Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hypoxia stimulus. |
SIRT2, CITED2 |
GO:0061433 | BP | cellular response to caloric restriction | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a of caloric restriction, insufficient food energy intake. |
SIRT2 |
GO:0061436 | BP | establishment of skin barrier | Establishment of the epithelial barrier, the functional barrier in the skin that limits its permeability. |
CLDN4, CLDN1, KRT1, KRT16, SFN, CYP26B1 |
GO:0061441 | BP | renal artery morphogenesis | The process in which the anatomical structure of a renal artery is generated and organized. Renal arteries supply the kidneys with blood. |
NRP1, PKD2 |
GO:0061444 | BP | endocardial cushion cell development | The process whose specific outcome is the progression of an endocardial cushion cell over time, from its formation to the mature state. |
JAG1 |
GO:0061445 | BP | endocardial cushion cell fate commitment | The commitment of a cell to an endocardial cushion cell fate and its capacity to differentiate into an endocardial cushion cell. |
ACVR1 |
GO:0061458 | BP | reproductive system development | The progression of the reproductive system over time from its formation to the mature structure. The reproductive system consists of the organs that function in reproduction. |
NDUFS6, PLEKHA5 |
GO:0061462 | BP | protein localization to lysosome | A process in which a protein is transported to, or maintained in, a location within a lysosome. |
CD81, RNF128, SH3BP4 |
GO:0061469 | BP | regulation of type B pancreatic cell proliferation | Any process that modulates the frequency, rate or extent of type B pancreatic cell proliferation. |
NR1D1, NR4A1, NR4A3, C7orf55, ERRFI1 |
GO:0061470 | BP | T follicular helper cell differentiation | The process in which a relatively unspecialized T cell acquires specialized features of a mature T follicular helper cell. |
GPR183, FOXP1, RC3H2 |
GO:0061474 | CC | phagolysosome membrane | The lipid bilayer surrounding a phagolysosome. |
LAMP1 |
GO:0061485 | BP | memory T cell proliferation | The expansion of a memory T cell population by cell division. |
DOCK8 |
GO:0061502 | BP | early endosome to recycling endosome transport | The directed movement of substances, in membrane-bounded vesicles, from the early sorting endosomes to the recycling endosomes. |
MYO1D, CORO1A |
GO:0061503 | MF | tRNA threonylcarbamoyladenosine dehydratase | Catalysis of the ATP-dependent dehydration of t6A to form cyclic t6A. |
UBA5 |
GO:0061504 | BP | cyclic threonylcarbamoyladenosine biosynthetic process | The chemical reactions and pathways resulting in the formation of cyclic threonylcarbamoyladenosine, a modified nucleoside found in some tRNA molecules. |
UBA5 |
GO:0061511 | BP | centriole elongation | The centrosome organization process by which a centriole increases in length as part of the process of replication. |
CENPJ |
GO:0061512 | BP | protein localization to cilium | A process in which a protein is transported to, or maintained in, a location within a cilium. |
RAB11FIP3, ARF4, CSNK1D, BBS1, IFT122, TULP4, WDR35, ATP6V1D |
GO:0061513 | MF | glucose 6-phosphate:inorganic phosphate antiporter activity | Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose 6-phosphate(out) + inorganic phosphate(in) = glucose 6-phosphate(in) + inorganic phosphate(out). |
SLC37A4 |
GO:0061518 | BP | microglial cell proliferation | The expansion of a microglial cell population by cell division. |
IL33, CLU |
GO:0061547 | MF | glycogen synthase activity, transferring glucose-1-phosphate | Catalysis of the reaction: UDP-glucose + (1,4)-alpha-D-glucosyl(n) = UMP + (1,4)-alpha-D-glucosyl(n)-glucose-1-phosphate. |
GYS1, GYS2 |
GO:0061548 | BP | ganglion development | The process whose specific outcome is the progression of a ganglion over time, from its formation to the mature structure. |
TULP3 |
GO:0061549 | BP | sympathetic ganglion development | The process whose specific outcome is the progression of a sympathetic ganglion over time, from its formation to the mature structure. |
NRP1, NRP2, CTNNB1, ASCL1, INSM1, SEMA3A |
GO:0061550 | BP | cranial ganglion development | The process whose specific outcome is the progression of a cranial ganglion over time, from its formation to the mature structure. |
CTNNB1 |
GO:0061551 | BP | trigeminal ganglion development | The process whose specific outcome is the progression of a trigeminal ganglion over time, from its formation to the mature structure. |
NRP1, SEMA3A |
GO:0061564 | BP | axon development | The progression of an axon over time. Covers axonogenesis (de novo generation of an axon) and axon regeneration (regrowth), as well as processes pertaining to the progression of the axon over time (fasciculation and defasciculation). |
TSPAN2, ZPR1, NEFH, GAP43, PLP1 |
GO:0061572 | BP | actin filament bundle organization | A process that results in the assembly, arrangement of constituent parts, or disassembly of an actin filament bundle. |
FAM101A, FAM101B |
GO:0061574 | CC | ASAP complex | A protein complex involved in regulation of mRNA processing and apoptosis. It binds to RNA in a sequence-independent manner and is recruited to the EJC prior to or during the splicing process. In humans the core proteins are RNPS1, SAP18 and ACIN1. |
SAP18, RNPS1 |
GO:0061575 | MF | cyclin-dependent protein serine/threonine kinase activator activity | Binds to and increases the activity of a cyclin-dependent protein serine/threonine kinase. |
CKS2, CKS1B |
GO:0061577 | BP | calcium ion transmembrane transport via high voltage-gated calcium channel | A process in which a calcium ion is transported from one side of a membrane to the other by means of a high voltage-gated calcium channel. |
CACNB3, CACNA2D1, CACNA1C |
GO:0061578 | MF | Lys63-specific deubiquitinase activity | Hydrolysis of Lys63-Linked ubiquitin unit(s) from a ubiquitinated protein. |
USP27X, ATXN3, CYLD |
GO:0061580 | BP | colon epithelial cell migration | The orderly movement of a colonic epithelial cell from one site to another, often during the development of a multicellular organism. |
ARSB |
GO:0061582 | BP | intestinal epithelial cell migration | The orderly movement of an intestinal epithelial cell from one site to another, often during the development of a multicellular organism. |
PTPN11 |
GO:0061589 | BP | calcium activated phosphatidylserine scrambling | The movement of a population of phosphatidylserine molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet as a result of a calcium stimulus. |
ANO6 |
GO:0061590 | BP | calcium activated phosphatidylcholine scrambling | The movement of a population of phosphatidylcholine molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet as a result of a calcium stimulus. |
ANO6 |
GO:0061591 | BP | calcium activated galactosylceramide scrambling | The movement of a population of galactosylceramide molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet as a result of a calcium stimulus. |
ANO6 |
GO:0061598 | MF | molybdopterin adenylyltransferase activity | Catalysis of the reaction ATP + molybdopterin = diphosphate + adenylyl-molybdopterin. |
GPHN |
GO:0061599 | MF | molybdopterin molybdotransferase activity | Catalysis of the reaction adenylyl-molybdopterin + molybdate = molybdenum cofactor + AMP. |
GPHN |
GO:0061614 | BP | pri-miRNA transcription from RNA polymerase II promoter | The cellular synthesis of primary microRNA (pri-miRNA) transcripts from a DNA template by RNA polymerase II, originating at an RNA polymerase II promoter. pri-miRNA transcripts are subsequently processed to produce the ~22nt miRNAs that function in gene regulation. |
ETS1, FOSL1 |
GO:0061617 | CC | MICOS complex | Mitochondrial inner membrane complex involved in maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. In Saccharomyces cerevisiae the complex has six subunits: MIC10, MIC12, MIC19, MIC26, MIC27, and MIC60. |
APOOL, APOO |
GO:0061618 | CC | sublamina densa | The part of the basement membrane that lies beneath the lamina densa, containing anchoring fibrils, anchoring plaques, collagen fibers, and elastic fibers. |
FRAS1 |
GO:0061621 | BP | canonical glycolysis | The glycolytic process that begins with the conversion of glucose to glucose-6-phosphate by glucokinase activity. Glycolytic processes are the chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP. |
PFKFB2, PGK1, ALDOA, GAPDH, ENO1, GPI, ENO2, ALDOC, ENO3, PKM, PFKFB1, PFKL, PGAM1, HK1, TPI1, PFKFB3, PFKFB4 |
GO:0061624 | BP | fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate | The chemical reactions and pathways resulting in the breakdown of fructose that results in the formation of dihydroxyacetone phosphate and glyceraldehyde-3-phosphate. |
ALDH1A1, TKFC |
GO:0061626 | BP | pharyngeal arch artery morphogenesis | The process in which the anatomical structures of a pharyngeal arch artery is generated and organized. The pharyngeal arch arteries are a series of six paired embryological vascular structures, the development of which give rise to several major arteries, such as the stapedial artery, the middle meningeal artery, the internal carotid artery and the pulmonary artery. |
BMP4, FOLR1, BMPR1A, TGFB2, BMPR2, HES1 |
GO:0061630 | MF | ubiquitin protein ligase activity | Catalysis of the transfer of ubiquitin to a substrate protein via the reaction X-ubiquitin + S --> X + S-ubiquitin, where X is either an E2 or E3 enzyme, the X-ubiquitin linkage is a thioester bond, and the S-ubiquitin linkage is an isopeptide bond between the C-terminal glycine of ubiquitin and the epsilon-amino group of lysine residues in the substrate. Note that this may include the extension of ubiquitin chains. |
TMEM189, WWP2, UBE2C, MDM4, SIAH2, MED7, PARK2, TRIM37, RAG1, CDC34, UBE2A, RNF144A, CDC42, UBE2H, RBX1, UBE2B, SKP1, XIAP, MDM2, CBLB, SKP2, PPIL2, UBE2V1, MED21, CUL2, CUL3, CUL4A, CUL4B, UBE2V2, UBE2S, MARCH8, RNF19B, RNF111, RNF165, UBR3, CBLL1, RNF144B, RBBP6, SYVN1, C19orf68, CACUL1, SIAH1, UBR1, UBE2J2, RNF152, RNF149, FBXO30, MARCH1, RNF128, MYLIP, RFFL, CUL5, MED12, MIB2, UBE2W, MED30, ITCH, UHRF2, UHRF1, RNF126, TRIM6, RNF38, WWP1, UBE2Z, AKTIP, RNF121, MED20, SMURF2, UBE2T, RAD18, RNF146, RNF19A, MED17, RLIM, RNF216, RNF181, RNF14, RABGEF1, AMFR, PRPF19, STUB1, PDZRN3, RNF24, RNF6, BTRC, ARIH1, RNF114 |