Search Geneontologies

Geneontologies

GO ID Ontology GO Term Term Definition Proteins

GO:0061113

BP

pancreas morphogenesis

Morphogenesis of the pancreas. Morphogenesis is the process in which anatomical structures are generated and organized.

NR5A2

GO:0061114

BP

branching involved in pancreas morphogenesis

The process in which the branches of the pancreas are generated and organized.

PROX1

GO:0061133

MF

endopeptidase activator activity

Increases the activity of an endopeptidase, any enzyme that hydrolyzes nonterminal peptide bonds in polypeptides.

PSME3, ADRM1

GO:0061136

BP

regulation of proteasomal protein catabolic process

Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome.

GPX1, PRKACA, PSME3, TMF1, PKD1, RHBDF1, PINK1, NUDT15, BTRC, UCHL5

GO:0061138

BP

morphogenesis of a branching epithelium

The process in which the anatomical structures of a branched epithelium are generated and organized.

SOX9, SOX8

GO:0061141

BP

lung ciliated cell differentiation

The process in which a relatively unspecialized cell acquires specialized features of a lung ciliated cell. A lung ciliated cell is a specialized lung epithelial cell that contains cilia for moving substances released from lung secretory cells.

NFIB

GO:0061145

BP

lung smooth muscle development

The process whose specific outcome is the progression of smooth muscle in the lung over time, from its formation to the mature structure.

SOX9

GO:0061149

BP

BMP signaling pathway involved in ureter morphogenesis

A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the shaping of the ureter. The ureter is a tube that extends from the kidney to the bladder.

BMP4

GO:0061151

BP

BMP signaling pathway involved in renal system segmentation

A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the segmentation of the renal system.

BMP4

GO:0061154

BP

endothelial tube morphogenesis

The process in which the anatomical structures of a tube are generated and organized from an endothelium. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells.

CTNNB1, RHOB, CCM2, PRKD2

GO:0061155

BP

pulmonary artery endothelial tube morphogenesis

The process in which the anatomical structures of a tube are generated and organized from the pulmonary artery endothelium. An pulmonary artery endothelium is an epithelium that lines the pulmonary artery.

BMP4

GO:0061156

BP

pulmonary artery morphogenesis

The process in which the anatomical structures of the pulmonary artery are generated and organized. The pulmonary artery is the artery that carries blood from the heart to the lungs.

JAG1

GO:0061157

BP

mRNA destabilization

Any process that decreases the stability of an mRNA molecule, making it more vulnerable to degradative processes. Messenger RNA is the intermediate molecule between DNA and protein. It includes UTR and coding sequences. It does not contain introns.

HNRNPR, PUM1, MEX3D, METTL14

GO:0061158

BP

3'-UTR-mediated mRNA destabilization

An mRNA destabilization process in which one or more RNA-binding proteins associate with the 3'-untranslated region (UTR) of an mRNA.

ZC3H12D, ZFP36, ZFP36L2, ZFP36L1, HNRNPD, CPEB3, KHSRP, QKI

GO:0061162

BP

establishment of monopolar cell polarity

The specification and formation of monopolar intracellular organization or cell growth patterns. Monopolar cell organization is directional organization along an axis.

MAP1B, GBF1

GO:0061178

BP

regulation of insulin secretion involved in cellular response to glucose stimulus

Any process that modulates the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose.

LRP5, NR1D1, EFNA5, EPHA5, CDK16, TIAM1, NR1H4, SYBU, NRXN1

GO:0061179

BP

negative regulation of insulin secretion involved in cellular response to glucose stimulus

Any process that decreases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose.

HMGCR, UCP2, NDUFAF2, ENY2

GO:0061180

BP

mammary gland epithelium development

The process whose specific outcome is the progression of the mammary gland epithelium over time, from its formation to the mature structure. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk.

JAK2, WNT2, WNT3

GO:0061182

BP

negative regulation of chondrocyte development

Any process that decreases the rate, frequency, or extent of the process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate.

FAM101A, FAM101B

GO:0061198

BP

fungiform papilla formation

The developmental process pertaining to the initial formation of a spongiform papilla from unspecified parts. The fungiform papilla is a mushroom-shaped papilla of the tongue.

CTNNB1, HDAC1, HDAC2

GO:0061202

CC

clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane

The lipid bilayer surrounding a clathrin-sculpted gamma-aminobutyric acid transport vesicle.

SYT1, VAMP2

GO:0061290

BP

canonical Wnt signaling pathway involved in metanephric kidney development

The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contribute to the progression of the metanephric kidney over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.

LGR4

GO:0061298

BP

retina vasculature development in camera-type eye

The process whose specific outcome is the progression of the vasculature of the retina over time, from its formation to the mature structure.

PDGFRB, PDGFRA, ACVR2B, BMPR2, HIF1A

GO:0061299

BP

retina vasculature morphogenesis in camera-type eye

The process in which the vasculature of the retina is generated and organized.

NRP1, NDP, RHOJ, FZD4

GO:0061301

BP

cerebellum vasculature morphogenesis

The process in which the vasculature of the cerebellum is generated and organized.

FZD4

GO:0061302

BP

smooth muscle cell-matrix adhesion

The binding of a smooth muscle cell to the extracellular matrix via adhesion molecules.

VTN, DDR1

GO:0061303

BP

cornea development in camera-type eye

The progression of the cornea over time, from its formation to the mature structure. The cornea is the transparent structure that covers the anterior of the eye.

WNT2B, WNT6

GO:0061304

BP

retinal blood vessel morphogenesis

The process whose specific outcome is the progression of a blood vessel of the retina over time, from its formation to the mature structure.

LRP5, CYP1B1, FZD4

GO:0061308

BP

cardiac neural crest cell development involved in heart development

The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the development of the heart.

MAPK3, MAPK1

GO:0061309

BP

cardiac neural crest cell development involved in outflow tract morphogenesis

The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the shaping of the outflow tract.

JAG1, HES1

GO:0061312

BP

BMP signaling pathway involved in heart development

A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the progression of the heart over time.

BMP4, BMPR1A, ACVR1

GO:0061314

BP

Notch signaling involved in heart development

The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell and contributing to the progression of the heart over time.

NOTCH1, JAG1, NOTCH2, DLL4, HEY1

GO:0061324

BP

canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation

The canonical Wnt signaling pathway that contributes to the modulation of the expansion of a population of cardiac outflow tract cells.

CTNNB1

GO:0061325

BP

cell proliferation involved in outflow tract morphogenesis

The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the outflow tract.

PITX2

GO:0061333

BP

renal tubule morphogenesis

The process in which the renal tubule is generated by specification of cell fate, through the maintenance of cell polarity, regulated cell proliferation and morphogenetic cell rearrangements, shape changes and growth. A renal tubule is a tube that filters, re-absorbs and secretes substances to rid an organism of waste and to play a role in fluid homeostasis.

MTSS1, MEF2C, PKD2

GO:0061337

BP

cardiac conduction

Transfer of an organized electrical impulse across the heart to coordinate the contraction of cardiac muscles. The process begins with generation of an action potential (in the sinoatrial node (SA) in humans) and ends with a change in the rate, frequency, or extent of the contraction of the heart muscles.

KCNK1, KCNK3, CACNB3, CACNA2D1, MEF2A, KCNH2, CACNA1C, KCNJ12, TRPM4, CACNG8, CACNG6, SPTBN4, KCNIP2, KCNK6

GO:0061343

BP

cell adhesion involved in heart morphogenesis

The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules that contributes to the shaping of the heart.

FLRT2

GO:0061347

BP

planar cell polarity pathway involved in outflow tract morphogenesis

The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the outflow tract.

WNT5A

GO:0061348

BP

planar cell polarity pathway involved in ventricular septum morphogenesis

The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the ventricular septum.

WNT5A

GO:0061349

BP

planar cell polarity pathway involved in cardiac right atrium morphogenesis

The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the cardiac right atrium.

WNT5A

GO:0061350

BP

planar cell polarity pathway involved in cardiac muscle tissue morphogenesis

The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the cardiac muscle tissue.

WNT5A

GO:0061351

BP

neural precursor cell proliferation

The multiplication or reproduction of neural precursor cells, resulting in the expansion of a cell population. A neural precursor cell is either a nervous system stem cell or a nervous system progenitor cell.

EPHB1, MELK, DBN1, ORC3

GO:0061354

BP

planar cell polarity pathway involved in pericardium morphogenesis

The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the pericardium.

WNT5A

GO:0061355

BP

Wnt protein secretion

The controlled release of a Wnt protein from a cell.

WLS

GO:0061357

BP

positive regulation of Wnt protein secretion

Any process that activates or increases the frequency, rate or extent of the controlled release of a Wnt protein from a cell.

WLS, VPS35

GO:0061364

BP

apoptotic process involved in luteolysis

The apoptotic process that contributes to luteolysis.

SLIT2, ROBO2

GO:0061368

BP

behavioral response to formalin induced pain

Any process that results in a change in the behaviour of an organism as a result of a formalin pain stimulus.

NTRK1

GO:0061370

BP

testosterone biosynthetic process

The chemical reactions and pathways resulting in the formation of testosterone, an androgen having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4 C-5.

HSD17B1, AKR1C3, STAR

GO:0061383

BP

trabecula morphogenesis

The process of shaping a trabecula in an organ. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue.

RHOA

GO:0061384

BP

heart trabecula morphogenesis

The process of shaping a trabecula in the heart. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue.

S1PR1, NOTCH1, TGFBR3, SOS1

GO:0061386

BP

closure of optic fissure

The closure of the temporary ventral gap in the optic cup that contributes to its shaping.

PHACTR4

GO:0061394

BP

regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance

Modulation of the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of an arsenic stimulus from compounds containing arsenic, including arsenates, arsenites, and arsenides.

ATF3

GO:0061395

BP

positive regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance

Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of an arsenic stimulus from compounds containing arsenic, including arsenates, arsenites, and arsenides.

ATF4

GO:0061402

BP

positive regulation of transcription from RNA polymerase II promoter in response to acidic pH

Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a pH stimulus with pH < 7.

PCK1

GO:0061418

BP

regulation of transcription from RNA polymerase II promoter in response to hypoxia

Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hypoxia stimulus.

BACH1, UBC, VEGFA, EGR1, ARNT, UBE2D3, RBX1, RPS27A, UBA52, EP300, CUL2, TCEB1, TCEB2, HIF1A, CREBBP, EPAS1, EGLN3, HIF3A

GO:0061419

BP

positive regulation of transcription from RNA polymerase II promoter in response to hypoxia

Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hypoxia stimulus.

VEGFA, NOTCH1, HIF1A

GO:0061428

BP

negative regulation of transcription from RNA polymerase II promoter in response to hypoxia

Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hypoxia stimulus.

SIRT2, CITED2

GO:0061433

BP

cellular response to caloric restriction

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a of caloric restriction, insufficient food energy intake.

SIRT2

GO:0061436

BP

establishment of skin barrier

Establishment of the epithelial barrier, the functional barrier in the skin that limits its permeability.

CLDN4, CLDN1, KRT1, KRT16, SFN, CYP26B1

GO:0061441

BP

renal artery morphogenesis

The process in which the anatomical structure of a renal artery is generated and organized. Renal arteries supply the kidneys with blood.

NRP1, PKD2

GO:0061444

BP

endocardial cushion cell development

The process whose specific outcome is the progression of an endocardial cushion cell over time, from its formation to the mature state.

JAG1

GO:0061445

BP

endocardial cushion cell fate commitment

The commitment of a cell to an endocardial cushion cell fate and its capacity to differentiate into an endocardial cushion cell.

ACVR1

GO:0061458

BP

reproductive system development

The progression of the reproductive system over time from its formation to the mature structure. The reproductive system consists of the organs that function in reproduction.

NDUFS6, PLEKHA5

GO:0061462

BP

protein localization to lysosome

A process in which a protein is transported to, or maintained in, a location within a lysosome.

CD81, RNF128, SH3BP4

GO:0061469

BP

regulation of type B pancreatic cell proliferation

Any process that modulates the frequency, rate or extent of type B pancreatic cell proliferation.

NR1D1, NR4A1, NR4A3, C7orf55, ERRFI1

GO:0061470

BP

T follicular helper cell differentiation

The process in which a relatively unspecialized T cell acquires specialized features of a mature T follicular helper cell.

GPR183, FOXP1, RC3H2

GO:0061474

CC

phagolysosome membrane

The lipid bilayer surrounding a phagolysosome.

LAMP1

GO:0061485

BP

memory T cell proliferation

The expansion of a memory T cell population by cell division.

DOCK8

GO:0061502

BP

early endosome to recycling endosome transport

The directed movement of substances, in membrane-bounded vesicles, from the early sorting endosomes to the recycling endosomes.

MYO1D, CORO1A

GO:0061503

MF

tRNA threonylcarbamoyladenosine dehydratase

Catalysis of the ATP-dependent dehydration of t6A to form cyclic t6A.

UBA5

GO:0061504

BP

cyclic threonylcarbamoyladenosine biosynthetic process

The chemical reactions and pathways resulting in the formation of cyclic threonylcarbamoyladenosine, a modified nucleoside found in some tRNA molecules.

UBA5

GO:0061511

BP

centriole elongation

The centrosome organization process by which a centriole increases in length as part of the process of replication.

CENPJ

GO:0061512

BP

protein localization to cilium

A process in which a protein is transported to, or maintained in, a location within a cilium.

RAB11FIP3, ARF4, CSNK1D, BBS1, IFT122, TULP4, WDR35, ATP6V1D

GO:0061513

MF

glucose 6-phosphate:inorganic phosphate antiporter activity

Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose 6-phosphate(out) + inorganic phosphate(in) = glucose 6-phosphate(in) + inorganic phosphate(out).

SLC37A4

GO:0061518

BP

microglial cell proliferation

The expansion of a microglial cell population by cell division.

IL33, CLU

GO:0061547

MF

glycogen synthase activity, transferring glucose-1-phosphate

Catalysis of the reaction: UDP-glucose + (1,4)-alpha-D-glucosyl(n) = UMP + (1,4)-alpha-D-glucosyl(n)-glucose-1-phosphate.

GYS1, GYS2

GO:0061548

BP

ganglion development

The process whose specific outcome is the progression of a ganglion over time, from its formation to the mature structure.

TULP3

GO:0061549

BP

sympathetic ganglion development

The process whose specific outcome is the progression of a sympathetic ganglion over time, from its formation to the mature structure.

NRP1, NRP2, CTNNB1, ASCL1, INSM1, SEMA3A

GO:0061550

BP

cranial ganglion development

The process whose specific outcome is the progression of a cranial ganglion over time, from its formation to the mature structure.

CTNNB1

GO:0061551

BP

trigeminal ganglion development

The process whose specific outcome is the progression of a trigeminal ganglion over time, from its formation to the mature structure.

NRP1, SEMA3A

GO:0061564

BP

axon development

The progression of an axon over time. Covers axonogenesis (de novo generation of an axon) and axon regeneration (regrowth), as well as processes pertaining to the progression of the axon over time (fasciculation and defasciculation).

TSPAN2, ZPR1, NEFH, GAP43, PLP1

GO:0061572

BP

actin filament bundle organization

A process that results in the assembly, arrangement of constituent parts, or disassembly of an actin filament bundle.

FAM101A, FAM101B

GO:0061574

CC

ASAP complex

A protein complex involved in regulation of mRNA processing and apoptosis. It binds to RNA in a sequence-independent manner and is recruited to the EJC prior to or during the splicing process. In humans the core proteins are RNPS1, SAP18 and ACIN1.

SAP18, RNPS1

GO:0061575

MF

cyclin-dependent protein serine/threonine kinase activator activity

Binds to and increases the activity of a cyclin-dependent protein serine/threonine kinase.

CKS2, CKS1B

GO:0061577

BP

calcium ion transmembrane transport via high voltage-gated calcium channel

A process in which a calcium ion is transported from one side of a membrane to the other by means of a high voltage-gated calcium channel.

CACNB3, CACNA2D1, CACNA1C

GO:0061578

MF

Lys63-specific deubiquitinase activity

Hydrolysis of Lys63-Linked ubiquitin unit(s) from a ubiquitinated protein.

USP27X, ATXN3, CYLD

GO:0061580

BP

colon epithelial cell migration

The orderly movement of a colonic epithelial cell from one site to another, often during the development of a multicellular organism.

ARSB

GO:0061582

BP

intestinal epithelial cell migration

The orderly movement of an intestinal epithelial cell from one site to another, often during the development of a multicellular organism.

PTPN11

GO:0061589

BP

calcium activated phosphatidylserine scrambling

The movement of a population of phosphatidylserine molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet as a result of a calcium stimulus.

ANO6

GO:0061590

BP

calcium activated phosphatidylcholine scrambling

The movement of a population of phosphatidylcholine molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet as a result of a calcium stimulus.

ANO6

GO:0061591

BP

calcium activated galactosylceramide scrambling

The movement of a population of galactosylceramide molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet as a result of a calcium stimulus.

ANO6

GO:0061598

MF

molybdopterin adenylyltransferase activity

Catalysis of the reaction ATP + molybdopterin = diphosphate + adenylyl-molybdopterin.

GPHN

GO:0061599

MF

molybdopterin molybdotransferase activity

Catalysis of the reaction adenylyl-molybdopterin + molybdate = molybdenum cofactor + AMP.

GPHN

GO:0061614

BP

pri-miRNA transcription from RNA polymerase II promoter

The cellular synthesis of primary microRNA (pri-miRNA) transcripts from a DNA template by RNA polymerase II, originating at an RNA polymerase II promoter. pri-miRNA transcripts are subsequently processed to produce the ~22nt miRNAs that function in gene regulation.

ETS1, FOSL1

GO:0061617

CC

MICOS complex

Mitochondrial inner membrane complex involved in maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. In Saccharomyces cerevisiae the complex has six subunits: MIC10, MIC12, MIC19, MIC26, MIC27, and MIC60.

APOOL, APOO

GO:0061618

CC

sublamina densa

The part of the basement membrane that lies beneath the lamina densa, containing anchoring fibrils, anchoring plaques, collagen fibers, and elastic fibers.

FRAS1

GO:0061621

BP

canonical glycolysis

The glycolytic process that begins with the conversion of glucose to glucose-6-phosphate by glucokinase activity. Glycolytic processes are the chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP.

PFKFB2, PGK1, ALDOA, GAPDH, ENO1, GPI, ENO2, ALDOC, ENO3, PKM, PFKFB1, PFKL, PGAM1, HK1, TPI1, PFKFB3, PFKFB4

GO:0061624

BP

fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate

The chemical reactions and pathways resulting in the breakdown of fructose that results in the formation of dihydroxyacetone phosphate and glyceraldehyde-3-phosphate.

ALDH1A1, TKFC

GO:0061626

BP

pharyngeal arch artery morphogenesis

The process in which the anatomical structures of a pharyngeal arch artery is generated and organized. The pharyngeal arch arteries are a series of six paired embryological vascular structures, the development of which give rise to several major arteries, such as the stapedial artery, the middle meningeal artery, the internal carotid artery and the pulmonary artery.

BMP4, FOLR1, BMPR1A, TGFB2, BMPR2, HES1

GO:0061630

MF

ubiquitin protein ligase activity

Catalysis of the transfer of ubiquitin to a substrate protein via the reaction X-ubiquitin + S --> X + S-ubiquitin, where X is either an E2 or E3 enzyme, the X-ubiquitin linkage is a thioester bond, and the S-ubiquitin linkage is an isopeptide bond between the C-terminal glycine of ubiquitin and the epsilon-amino group of lysine residues in the substrate. Note that this may include the extension of ubiquitin chains.

TMEM189, WWP2, UBE2C, MDM4, SIAH2, MED7, PARK2, TRIM37, RAG1, CDC34, UBE2A, RNF144A, CDC42, UBE2H, RBX1, UBE2B, SKP1, XIAP, MDM2, CBLB, SKP2, PPIL2, UBE2V1, MED21, CUL2, CUL3, CUL4A, CUL4B, UBE2V2, UBE2S, MARCH8, RNF19B, RNF111, RNF165, UBR3, CBLL1, RNF144B, RBBP6, SYVN1, C19orf68, CACUL1, SIAH1, UBR1, UBE2J2, RNF152, RNF149, FBXO30, MARCH1, RNF128, MYLIP, RFFL, CUL5, MED12, MIB2, UBE2W, MED30, ITCH, UHRF2, UHRF1, RNF126, TRIM6, RNF38, WWP1, UBE2Z, AKTIP, RNF121, MED20, SMURF2, UBE2T, RAD18, RNF146, RNF19A, MED17, RLIM, RNF216, RNF181, RNF14, RABGEF1, AMFR, PRPF19, STUB1, PDZRN3, RNF24, RNF6, BTRC, ARIH1, RNF114

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