GO:0060842

BP

arterial endothelial cell differentiation

The process in which a relatively unspecialized endothelial cell acquires specialized features of an arterial endothelial cell, a thin flattened cell that lines the inside surfaces of arteries.

NOTCH1, HEY1

GO:0060843

BP

venous endothelial cell differentiation

The process in which a relatively unspecialized endothelial cell acquires specialized features of a venous endothelial cell, a thin flattened cell that lines the inside surfaces of veins.

NOTCH1

GO:0060849

BP

regulation of transcription involved in lymphatic endothelial cell fate commitment

Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the commitment of a venous endothelial cell to a lymphatic endothelial cell.

NR2F2, PROX1

GO:0060850

BP

regulation of transcription involved in cell fate commitment

Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the commitment of a cell to a specific fate.

CEBPB, RORA, PPARG

GO:0060856

BP

establishment of blood-brain barrier

Establishment of the barrier between the blood and the brain. The cells in the brain are packed tightly together preventing the passage of most molecules from the blood into the brain. Only lipid soluble molecules or those that are actively transported can pass through the blood-brain barrier.

LSR, MFSD2A

GO:0060873

BP

anterior semicircular canal development

The progession of the anterior semicircular canal from its initial formation to the mature structure.

GLI3

GO:0060875

BP

lateral semicircular canal development

The progession of the lateral semicircular canal from its initial formation to the mature structure.

GLI3

GO:0060876

BP

semicircular canal formation

The developmental process pertaining to the initial formation of the semicircular canal from the otic vesicle. This process begins with the regionalization of the vesicle that specifies the area where the vesicles will form and continues through the process of fusion which forms the initial tubes.

HOXA1

GO:0060900

BP

embryonic camera-type eye formation

The developmental process pertaining to the initial formation of a camera-type eye from unspecified neurectoderm. This process begins with the differentiation of cells that form the optic field and ends when the optic cup has attained its shape.

TWIST1

GO:0060904

BP

regulation of protein folding in endoplasmic reticulum

Any process that modulates the rate, frequency or extent of the protein folding process that takes place in the endoplasmic reticulum (ER). Secreted, plasma membrane and organelle proteins are folded in the ER, assisted by chaperones and foldases (protein disulphide isomerases), and additional factors required for optimal folding (ATP, Ca2+ and an oxidizing environment to allow disulfide bond formation).

HSPA5

GO:0060907

BP

positive regulation of macrophage cytokine production

Any process that increases the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.

TLR4, SEMA7A, CD74, CD36, WNT5A, SPON2, GPRC5B

GO:0060912

BP

cardiac cell fate specification

The process involved in the specification of cardiac cell identity. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment.

TENM4

GO:0060913

BP

cardiac cell fate determination

The process involved in cardiac cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment.

SOX17

GO:0060914

BP

heart formation

The developmental process pertaining to the initial formation of the heart from unspecified parts. This process begins with the specific processes that contribute to the appearance of the heart field and the arrival of cardiac neural crest to the heart region. The process ends when the structural rudiment is recognizable.

BMPR1A, SOX17

GO:0060915

BP

mesenchymal cell differentiation involved in lung development

The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell of the lung. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types.

FGFR2

GO:0060916

BP

mesenchymal cell proliferation involved in lung development

The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population that contributes to the progression of the lung over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets.

FGFR2, CTNNB1

GO:0060923

BP

cardiac muscle cell fate commitment

The commitment of cells to specific cardiac muscle cell fates and their capacity to differentiate into cardiac muscle cells. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction.

WT1, ACVR1

GO:0060931

BP

sinoatrial node cell development

The process whose specific outcome is the progression of a sinoatrial (SA) node cell over time, from its formation to the mature state. SA node cells are pacemaker cells that are found in the sinoatrial node.

BVES

GO:0060939

BP

epicardium-derived cardiac fibroblast cell development

The process whose specific outcome is the progression of an epicardial-derived cardiac fibroblast over time, from its formation to the mature state. A epicardial-derived cardiac fibroblast is a connective tissue cell of the heart that arises from the epicardium and secretes an extracellular matrix rich in collagen and other macromolecules.

TGFBR3

GO:0060947

BP

cardiac vascular smooth muscle cell differentiation

The process in which a relatively unspecialized cell acquires specialized features of a cardiac vascular smooth muscle cell. A cardiac vascular smooth muscle cell covers the heart vasculature and lacks transverse striations in its constituent fibers.

GATA6

GO:0060948

BP

cardiac vascular smooth muscle cell development

The process whose specific outcome is the progression of a cardiac vascular smooth muscle cell over time, from its formation to the mature state.

VEGFA, NOTCH1

GO:0060956

BP

endocardial cell differentiation

The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an endocardial cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart. The endocardium is the innermost layer of tissue of the heart, and lines the heart chambers.

NOTCH1, NRG1, SMAD4, SOX17

GO:0060964

BP

regulation of gene silencing by miRNA

Any process that modulates the rate, frequency, or extent of the downregulation of gene expression through the action of microRNAs (miRNAs), endogenous 21-24 nucleotide small RNAs processed from stem-loop RNA precursors (pre-miRNAs). Once incorporated into a RNA-induced silencing complex (RISC), miRNAs can downregulate gene expression by either of two posttranscriptional mechanisms: mRNA cleavage or translational repression.

FMR1, PUM1, PUM2, LIN28A

GO:0060965

BP

negative regulation of gene silencing by miRNA

Any process that decreases the rate, frequency, or extent of the downregulation of gene expression through the action of microRNAs (miRNAs), endogenous 21-24 nucleotide small RNAs processed from stem-loop RNA precursors (pre-miRNAs). Once incorporated into a RNA-induced silencing complex (RISC), miRNAs can downregulate gene expression by either of two posttranscriptional mechanisms: mRNA cleavage or translational repression.

TGFB1, POU5F1, ELAVL1

GO:0060968

BP

regulation of gene silencing

Any process that modulates the rate, frequency, or extent of gene silencing, the transcriptional or post-transcriptional process carried out at the cellular level that results in long-term gene inactivation.

CDK2, HIST1H3D

GO:0060971

BP

embryonic heart tube left/right pattern formation

The pattern specification process that results in the subdivision of the left/right axis of the embryonic heart tube in space to define an area or volume in which specific patterns of cell differentiation will take place.

CITED2, IFT122

GO:0060972

BP

left/right pattern formation

The pattern specification process that results in the subdivision of the left/right axis in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment.

CITED2

GO:0060973

BP

cell migration involved in heart development

The orderly movement of a cell from one site to another that will contribute to the progression of the heart over time, from its initial formation, to the mature organ.

BVES, NDRG4

GO:0060976

BP

coronary vasculature development

The process whose specific outcome is the progression of the blood vessels of the heart over time, from its formation to the mature structure.

SMAD6, BMP4, VEGFB, NDST1, AP2B1, LRP2, PTK7, LTBP1, TAB1, PCSK5, PRICKLE1, DCTN5, ADAMTS6, SUFU, PLXND1

GO:0060978

BP

angiogenesis involved in coronary vascular morphogenesis

Blood vessel formation in the heart when new vessels emerge from the proliferation of pre-existing blood vessels.

NRP1, TGFBR1

GO:0060979

BP

vasculogenesis involved in coronary vascular morphogenesis

The differentiation of endothelial cells from progenitor cells that contributes to blood vessel development in the heart, and the de novo formation of blood vessels and tubes.

NOTCH1, TGFBR3

GO:0060981

BP

cell migration involved in coronary angiogenesis

The orderly movement of a cell from one site to another that will contribute to the formation of new blood vessels in the heart from pre-existing blood vessels.

PDGFRB

GO:0060982

BP

coronary artery morphogenesis

The process in which the anatomical structures of coronary arteries are generated and organized. Coronary arteries are blood vessels that transport blood to the heart muscle.

NRP1, TBX1, VEGFA, TGFBR1, NOTCH1

GO:0060987

CC

lipid tube

A macromolecular complex that contains a tube of lipid surrounded by a protein coat.

BIN1

GO:0060988

BP

lipid tube assembly

The aggregation, arrangement and bonding together of a set of macromolecules to form a macromolecular complex that contains a tube of lipid surrounded by a protein coat involved in membrane shaping of vesicle membranes as they fuse or undergo fission.

BIN1, SNX9

GO:0060992

BP

response to fungicide

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fungicide stimulus. Fungicides are chemicals used to kill fungi.

KDM1A, SRD5A1, STAR, KDM5B

GO:0060993

BP

kidney morphogenesis

Morphogenesis of a kidney. A kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.

PRKX, SOX4, NPHP3

GO:0060996

BP

dendritic spine development

The process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission.

UBA6, ACSL4, ARF4, EPHB2, EPHB1, PAK2, SLC9A6

GO:0060997

BP

dendritic spine morphogenesis

The process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission.

PAK3, EPHB2, EPHB1, PTEN, DLG4, HDAC6

GO:0060998

BP

regulation of dendritic spine development

Any process that modulates the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure.

MEF2C, FMR1, SDK1, CPEB3

GO:0060999

BP

positive regulation of dendritic spine development

Any process that increases the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure.

APOE, PSEN1, ARF1, NRG1, FMR1, CAMK1, NLGN1, CPEB3, LLPH

GO:0061000

BP

negative regulation of dendritic spine development

Any process that decreases the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure.

HDAC2, PLK2, ASAP1

GO:0061001

BP

regulation of dendritic spine morphogenesis

Any process that modulates the rate, frequency, or extent of dendritic spine morphogenesis, the process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission.

CFL1, EPHA4, CDK5, PDLIM5

GO:0061002

BP

negative regulation of dendritic spine morphogenesis

Any process that decreases the rate, frequency, or extent of dendritic spine morphogenesis, the process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission.

EFNA1, PTEN, NLGN1

GO:0061003

BP

positive regulation of dendritic spine morphogenesis

Any process that modulates the rate, frequency, or extent of dendritic spine morphogenesis, the process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission.

PAK3, ITPKA, TIAM1, CAPRIN1

GO:0061005

BP

cell differentiation involved in kidney development

The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the kidney as it progresses from its formation to the mature state.

GLI3, PTCH1

GO:0061009

BP

common bile duct development

The progression of the common bile duct over time, from its formation to the mature structure. The common bile duct is formed from the joining of the common hepatic duct running from the liver, and the cystic duct running from the gall bladder. The common bile duct transports bile from the liver and gall bladder to the intestine.

HES1, SOX17, MKS1

GO:0061010

BP

gall bladder development

The progression of the gall bladder over time, from its initial formation to the mature structure. The gall bladder is a cavitated organ that stores bile.

HHEX, NIPBL, SOX17

GO:0061011

BP

hepatic duct development

The progression of the hepatic duct over time, from its formation to the mature structure. The hepatic duct is the duct that leads from the liver to the common bile duct.

HHEX

GO:0061014

BP

positive regulation of mRNA catabolic process

Any process that increases the rate, frequency, or extent of a mRNA catabolic process, the chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.

CNOT1, HNRNPR, PNPT1, KHSRP, CNOT7

GO:0061017

BP

hepatoblast differentiation

The process in which a relatively unspecialized cell acquires specialized features of a hepatoblast. A hepatoblast is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into hepatocytes and cholangiocytes.

HHEX

GO:0061024

BP

membrane organization

A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

GNPAT, TBC1D4, PMP2, RALA, YWHAB, SFN, PRKCI, YWHAE, YWHAZ, YWHAH, CLN3, DHCR24, SGCB, CCDC88A, LPCAT2, SGCD, SGCZ, CHP1, LNPEP

GO:0061025

BP

membrane fusion

The membrane organization process that joins two lipid bilayers to form a single membrane.

SNAP23, GOSR2, STX11, SNAP29, VAMP2, RABEP1, VAMP3, HACE1, CHP1, NAPB, BET1L, VAPA, VTI1B, BLOC1S6, NSFL1C

GO:0061026

BP

cardiac muscle tissue regeneration

The regrowth of cardiac muscle tissue to repair injured or damaged muscle fibers in the postnatal stage.

ERBB4

GO:0061028

BP

establishment of endothelial barrier

The establishment of a barrier between endothelial cell layers, such as those in the brain, lung or intestine, to exert specific and selective control over the passage of water and solutes, thus allowing formation and maintenance of compartments that differ in fluid and solute composition.

ICAM1, EZR, RDX, F2RL1, RAP1A, PDE4D, RAPGEF1, MYADM

GO:0061029

BP

eyelid development in camera-type eye

The progression of the eyelid in a camera-type eye from its formation to the mature state. The eyelid is a membranous cover that helps protect and lubricate the eye.

EGFR, JUN, INHBA, SOS1, HDAC1, TWIST1, HDAC2

GO:0061030

BP

epithelial cell differentiation involved in mammary gland alveolus development

The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland alveolus.

ID2, HIF1A

GO:0061031

BP

endodermal digestive tract morphogenesis

The process in which the anatomical structures of the endodermal digestive tract are generated and organized. The endodermal digestive tract includes those portions of the digestive tract that are derived from endoderm.

ID2, PITX2, SOX17

GO:0061032

BP

visceral serous pericardium development

The progression of the visceral serous pericardium from its formation to the mature structure. The visceral serous pericardium is the inner layer of the pericardium.

WT1

GO:0061033

BP

secretion by lung epithelial cell involved in lung growth

The controlled release of liquid by a lung epithelial cell that contributes to an increase in size of the lung as part of its development.

FGF7

GO:0061034

BP

olfactory bulb mitral cell layer development

The progression of the olfactory bulb mitral cell layer over time from its initial formation until its mature state. The mitral cell layer is composed of pyramidal neurons whose cell bodies are located between the granule cell layer and the plexiform layer.

OGDH

GO:0061035

BP

regulation of cartilage development

Any process that modulates the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.

TGFB1

GO:0061036

BP

positive regulation of cartilage development

Any process that increases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.

CYR61, BMP10, BMP2, BMP4, BMP1, SOX6, WNT5A, SOX9, ZBTB16, BMPR2, SMAD1

GO:0061037

BP

negative regulation of cartilage development

Any process that decreases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.

LEP, TGFB2

GO:0061038

BP

uterus morphogenesis

The process in which anatomical structures of the uterus are generated and organized.

NIPBL, KDM5B

GO:0061040

BP

female gonad morphogenesis

The process in which a female gonad is generated and organized.

SMAD4

GO:0061041

BP

regulation of wound healing

Any process that modulates the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury.

PLAU, SRSF6, TNFRSF12A

GO:0061042

BP

vascular wound healing

Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature.

MCAM, ADIPOR2, NDNF, HPSE

GO:0061043

BP

regulation of vascular wound healing

Any process that modulates the rate, frequency, or extent of blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature.

TNFAIP3

GO:0061044

BP

negative regulation of vascular wound healing

Any process that decreases the rate, frequency, or extent of blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature.

SERPINE1

GO:0061045

BP

negative regulation of wound healing

Any process that decreases the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury.

CASK, APCS, HMGCR, SERPINE1, FGF2, GJA1, SMAD3, WFDC1

GO:0061046

BP

regulation of branching involved in lung morphogenesis

Any process that modulates the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units.

SOX9

GO:0061047

BP

positive regulation of branching involved in lung morphogenesis

Any process that modulates the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units.

BMP4

GO:0061048

BP

negative regulation of branching involved in lung morphogenesis

Any process that decreases the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units.

TNF

GO:0061049

BP

cell growth involved in cardiac muscle cell development

The growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state.

SORBS2, AGT, GATA4, AGTR2, CAMK2D, PDLIM5

GO:0061051

BP

positive regulation of cell growth involved in cardiac muscle cell development

Any process that increases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state.

IGF1, EDN1, HAMP, AKAP6

GO:0061052

BP

negative regulation of cell growth involved in cardiac muscle cell development

Any process that decreases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state.

G6PD

GO:0061053

BP

somite development

The progression of a somite from its initial formation to the mature structure. Somites are mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo.

MTHFD1, MEOX1, PPP2R3A, PTCH1, RBBP6

GO:0061056

BP

sclerotome development

The progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra.

MEOX1

GO:0061061

BP

muscle structure development

The progression of a muscle structure over time, from its formation to its mature state. Muscle structures are contractile cells, tissues or organs that are found in multicellular organisms.

CAPN3, RNF165

GO:0061072

BP

iris morphogenesis

The process in which the iris is generated and organized. The iris is an anatomical structure in the eye whose opening forms the pupil. The iris is responsible for controlling the diameter and size of the pupil and the amount of light reaching the retina.

WNT2, HIF1A, WNT2B, PITX2, HIPK2

GO:0061073

BP

ciliary body morphogenesis

The process in which the ciliary body generated and organized. The ciliary body is the circumferential tissue inside the eye composed of the ciliary muscle and ciliary processes.

JAG1

GO:0061074

BP

regulation of neural retina development

Any process that modulates the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells.

DLL4

GO:0061077

BP

chaperone-mediated protein folding

The process of inhibiting aggregation and assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that is dependent on interaction with a chaperone.

TOR1A, CRTAP, CLU, PDIA4, PPIB, FKBP2, CALR, CANX, FKBP3, FKBP4, PPID, FKBP5, FKBP10, FKBP14, FKBP11, CHORDC1, FKBP7

GO:0061078

BP

positive regulation of prostaglandin secretion involved in immune response

Any process that activates or increases the frequency, rate or extent of the regulated release of a prostaglandin from a cell and contributes to the immune response.

MIF

GO:0061081

BP

positive regulation of myeloid leukocyte cytokine production involved in immune response

Any process that modulates the rate, frequency, or extent of the production of a cytokine that contributes to the immune response.

MIF

GO:0061084

BP

negative regulation of protein refolding

Any process that decreases the rate, frequency, or extent of protein refolding. Protein refolding is the process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones.

PDCL, BAG5

GO:0061086

BP

negative regulation of histone H3-K27 methylation

Any process that decreases the rate, frequency, or extent of histone H3-K27 methylation. Histone H3-K27 methylation is the modification of histone H3 by addition of a methyl group to lysine at position 27 of the histone.

H2AFY, SUPT6H, MTF2

GO:0061087

BP

positive regulation of histone H3-K27 methylation

Any process that increases the rate, frequency, or extent of histone H3-K27 methylation. Histone H3-K27 methylation is the modification of histone H3 by addition of a methyl group to lysine at position 27 of the histone.

OGT, PHF19, MTF2

GO:0061088

BP

regulation of sequestering of zinc ion

Any process that modulates the rate, frequency, or extent of sequestering of zinc ion. Sequestering of zinc ion is the process of binding or confining zinc ions such that they are separated from other components of a biological system.

AP3D1, SLC30A8, SLC30A1

GO:0061097

BP

regulation of protein tyrosine kinase activity

Any process that modulates the rate, frequency, or extent of protein tyrosine kinase activity.

RAP2B

GO:0061098

BP

positive regulation of protein tyrosine kinase activity

Any process that increases the rate, frequency, or extent of protein tyrosine kinase activity.

GREM1, AGT, PDGFB, CSF1R, ACE, CCL5, ERBB3, CD24, PAK2, UNC119, GAS6, FAM150B, ABI1, AFAP1L2, HSPH1, GPRC5B, GHRL

GO:0061099

BP

negative regulation of protein tyrosine kinase activity

Any process that decreases the rate, frequency, or extent of protein tyrosine kinase activity.

SH3BP5, PTPN2, RACK1, CAV1, HYAL2, SH3BP5L

GO:0061100

BP

lung neuroendocrine cell differentiation

The process in which a relatively unspecialized cell acquires specialized features of a neuroendocrine cell of the lung epithelium.

ASCL1

GO:0061101

BP

neuroendocrine cell differentiation

The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a neuroendocrine cell. A neuroendocrine cell is a cell that receives input form a neuron which controls the secretion of an endocrine substance.

BCCIP

GO:0061102

BP

stomach neuroendocrine cell differentiation

The process in which a relatively unspecialized cell acquires specialized features of a neuroendocrine cell of the stomach epithelium.

ASCL1

GO:0061103

BP

carotid body glomus cell differentiation

The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a glomus cell of the carotid body. The carotid body is a specialized chemosensory organ that helps respond to hypoxia.

ASCL1

GO:0061104

BP

adrenal chromaffin cell differentiation

The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an adrenal chromaffin cell. An adrenal chromaffin cell is a neuroendocrine cell that stores epinephrine secretory vesicles.

ASCL1, INSM1

GO:0061106

BP

negative regulation of stomach neuroendocrine cell differentiation

Any process that decreases the rate, frequency or extent of the differentiation of a neuroendocrine cell in the stomach.

HES1

GO:0061108

BP

seminal vesicle epithelium development

The progression of the seminal vesicle epithelium over time, from its formation to the mature structure.

SERPINE2