| GO ID | Ontology | GO Term | Term Definition |
Proteins |
GO:0060397 | BP | JAK-STAT cascade involved in growth hormone signaling pathway | The process in which STAT proteins (Signal Transducers and Activators of Transcription) are activated by members of the JAK (janus activated kinase) family of tyrosine kinases, following the binding of physiological ligands to the growth hormone receptor. Once activated, STATs dimerize and translocate to the nucleus and modulate the expression of target genes. |
JAK2, PRL, GH1, LYN, GHR, PRLR, MAPK3, MAPK1, STAT3, STAT5A, STAT5B, JAK3 |
GO:0060399 | BP | positive regulation of growth hormone receptor signaling pathway | Any process that increases the rate, frequency or extent of the growth hormone receptor signaling pathway. The growth hormone receptor signaling pathway is the series of molecular signals generated as a consequence of growth hormone receptor binding to its physiological ligand. |
JAK2, MBD5, GHRL |
GO:0060400 | BP | negative regulation of growth hormone receptor signaling pathway | Any process that decreases the rate, frequency or extent of the growth hormone receptor signaling pathway. The growth hormone receptor signaling pathway is the series of molecular signals generated as a consequence of growth hormone receptor binding to its physiological ligand. |
LEPROT |
GO:0060401 | BP | cytosolic calcium ion transport | The directed movement of calcium ions (Ca2+) into, out of or within the cytosol. |
CTGF |
GO:0060402 | BP | calcium ion transport into cytosol | The directed movement of calcium ions (Ca2+) into the cytosol. |
ADRA1A, CACNB3, CACNA2D1, CACNA1C, ITPR3, RYR2 |
GO:0060405 | BP | regulation of penile erection | Any process that modulates the rate, frequency or extent of penile erection. Penile erection is the hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow. |
CNR1 |
GO:0060406 | BP | positive regulation of penile erection | Any process that increases the rate, frequency or extent of penile erection. Penile erection is the hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow. |
OXTR |
GO:0060407 | BP | negative regulation of penile erection | Any process that increases the rate, frequency or extent of penile erection. Penile erection is the hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow. |
ADA |
GO:0060411 | BP | cardiac septum morphogenesis | The process in which the anatomical structure of a cardiac septum is generated and organized. A cardiac septum is a partition that separates parts of the heart. |
DHRS3, NOTCH1, JAG1, MDM2, CHD7, HEY1 |
GO:0060412 | BP | ventricular septum morphogenesis | The developmental process in which a ventricular septum is generated and organized. A ventricular septum is an anatomical structure that separates the lower chambers (ventricles) of the heart from one another. |
SMAD7, GJA5, TGFBR1, TGFBR2, NOTCH1, TGFB2, TGFBR3, ACVR1, SOX4, SMAD4, BMPR2, HES1, ZFPM2, PROX1, RBM15, PITX2, CITED2, HEYL, HEY1 |
GO:0060413 | BP | atrial septum morphogenesis | The developmental process in which atrial septum is generated and organized. The atrial septum separates the upper chambers (the atria) of the heart from one another. |
CYR61, GJA5, GATA4, TGFB2, NOTCH2, BMPR2 |
GO:0060414 | BP | aorta smooth muscle tissue morphogenesis | The process in which the structure of the smooth muscle tissue surrounding the aorta is generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body. |
COL3A1, MYLK, PROX1 |
GO:0060415 | BP | muscle tissue morphogenesis | The process in which the anatomical structures of muscle tissue are generated and organized. Muscle tissue consists of a set of cells that are part of an organ and carry out a contractive function. |
TBX1, SHOX2 |
GO:0060416 | BP | response to growth hormone | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth hormone stimulus. Growth hormone is a peptide hormone that binds to the growth hormone receptor and stimulates growth. |
ASS1, SRD5A1, NME2, IGFBP5, AKT1, RBBP4, CACYBP |
GO:0060420 | BP | regulation of heart growth | Any process that modulates the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart. |
DUSP6 |
GO:0060421 | BP | positive regulation of heart growth | Any process that increases the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart. |
ACACB, WT1, PROX1 |
GO:0060425 | BP | lung morphogenesis | The process in which the anatomical structures of the lung are generated and organized. |
TCF21, BMP4, MAPK3, MAPK1, ID1, MAPK8IP3 |
GO:0060426 | BP | lung vasculature development | The biological process whose specific outcome is the progression of a lung vasculature from an initial condition to its mature state. This process begins with the formation of the lung vasculature and ends with the mature structure. The lung vasculature is composed of the tubule structures that carry blood or lymph in the lungs. |
TCF21, LIF, ID1, ERRFI1 |
GO:0060428 | BP | lung epithelium development | The biological process whose specific outcome is the progression of the lung epithelium from an initial condition to its mature state. This process begins with the formation of lung epithelium and ends with the mature structure. The lung epithelium is the specialized epithelium that lines the inside of the lung. |
PKD1, ERRFI1 |
GO:0060429 | BP | epithelium development | The process whose specific outcome is the progression of an epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. |
SNAI2, CHD7 |
GO:0060430 | BP | lung saccule development | The biological process whose specific outcome is the progression of a lung saccule from an initial condition to its mature state. The lung saccule is the primitive gas exchange portion of the lung composed of type I and type II cells. |
CREB1, NKX2-1, GATA6 |
GO:0060431 | BP | primary lung bud formation | The morphogenetic process in which the foregut region specified to become the lung forms the initial left and right buds. |
HHEX, RDH10 |
GO:0060433 | BP | bronchus development | The biological process whose specific outcome is the progression of a bronchus from an initial condition to its mature state. This process begins with the formation of the bronchus and ends with the mature structure. The bronchus is the portion of the airway that connects to the lungs. |
BMP4 |
GO:0060434 | BP | bronchus morphogenesis | The process in which the bronchus is generated and organized. The bronchus is the portion of the airway that connects to the lungs. |
TULP3, TGFBR2 |
GO:0060435 | BP | bronchiole development | The biological process whose specific outcome is the progression of a bronchiole from an initial condition to its mature state. This process begins with the formation of the bronchiole and ends with the mature structure. A bronchiole is the first airway branch that no longer contains cartilage; it is a branch of the bronchi. |
TCF21 |
GO:0060437 | BP | lung growth | The increase in size or mass of a lung. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax. |
SPRY2 |
GO:0060438 | BP | trachea development | The process whose specific outcome is the progression of a trachea over time, from its formation to the mature structure. The trachea is the portion of the airway that attaches to the bronchi as it branches. |
BMP4 |
GO:0060440 | BP | trachea formation | The process pertaining to the initial formation of a trachea from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the trachea is recognizable. The trachea is the portion of the airway that attaches to the bronchi as it branches. |
BMP4, MAPK3, MAPK1, CTNNB1, TGFBR2, MAP2K1 |
GO:0060441 | BP | epithelial tube branching involved in lung morphogenesis | The process in which a highly ordered sequence of patterning events generates the branched epithelial tubes of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units. |
KRAS, BMP4, CTNNB1, NKX2-1, SOX9, DAG1, DLG5, HHIP, ESRP2, CTSZ |
GO:0060442 | BP | branching involved in prostate gland morphogenesis | The process in which the branching structure of the prostate gland is generated and organized. A branch is a division or offshoot from a main stem. |
BMP4, FGFR2, FEM1B |
GO:0060443 | BP | mammary gland morphogenesis | The process in which anatomical structures of the mammary gland are generated and organized. Morphogenesis refers to the creation of shape. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk. |
TGFBR2 |
GO:0060444 | BP | branching involved in mammary gland duct morphogenesis | The process in which the branching structure of the mammary gland duct is generated and organized. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk. |
LRP5, DDR1, KDM5B, BTRC |
GO:0060445 | BP | branching involved in salivary gland morphogenesis | The process in which the branching structure of the salivary gland is generated and organized. |
IL6, FGFR1, FGF7, FGFR2, TGM2, DAG1, ESRP2 |
GO:0060447 | BP | bud outgrowth involved in lung branching | The process in which a region of the lung epithelium initiates an outgrowth. |
TNC |
GO:0060448 | BP | dichotomous subdivision of terminal units involved in lung branching | The process in which a lung bud bifurcates. |
CTSH |
GO:0060449 | BP | bud elongation involved in lung branching | The process in which a bud in the lung grows out from the point where it is formed. |
SPRY2, SPRY1, BMP4, FGFR2, YAP1, RDH10 |
GO:0060452 | BP | positive regulation of cardiac muscle contraction | Any process that increases the frequency, rate or extent of cardiac muscle contraction. |
HSP90AA1, CTGF, ADRA1A, RGS2 |
GO:0060454 | BP | positive regulation of gastric acid secretion | Any process that increases the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion. |
OPRL1, TRPV1 |
GO:0060455 | BP | negative regulation of gastric acid secretion | Any process that decreases the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion. |
OXTR, PTGER3 |
GO:0060460 | BP | left lung morphogenesis | The process in which anatomical structures of the left lung are generated and organized. |
PITX2 |
GO:0060463 | BP | lung lobe morphogenesis | The process in which the anatomical structures of a lung lobe are generated and organized. A lung lobe is a projection that extends from the lung. |
LIF, FGFR2, TGFBR2 |
GO:0060466 | BP | activation of meiosis involved in egg activation | Any process that starts the inactive process of meiosis in an egg after the egg has been fertilized or physiologically activated. Eggs generally arrest in meiosis and complete the process after activation. |
PLCB1 |
GO:0060479 | BP | lung cell differentiation | The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features of a mature cell found in the lung. Differentiation includes the processes involved in commitment of a cell to a specific fate. |
CTNNB1 |
GO:0060484 | BP | lung-associated mesenchyme development | The biological process whose specific outcome is the progression of a lung-associated mesenchyme from an initial condition to its mature state. This process begins with the formation of lung-associated mesenchyme and ends with the mature structure. Lung-associated mesenchyme is the tissue made up of loosely connected mesenchymal cells in the lung. |
FGFR1, FGFR2, FGF9, CTNNB1, PTK7 |
GO:0060485 | BP | mesenchyme development | The process whose specific outcome is the progression of a mesenchymal tissue over time, from its formation to the mature structure. A mesenchymal tissue is made up of loosely packed stellate cells. |
BMP2, BNC2 |
GO:0060486 | BP | Clara cell differentiation | The process in which a relatively unspecialized cell acquires specialized features of a Clara cell. A Clara cell is an unciliated epithelial cell found in the respiratory and terminal bronchioles. |
NFIB, NKX2-1, GATA6 |
GO:0060487 | BP | lung epithelial cell differentiation | The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell that contributes to the epithelium of the lung. |
YAP1, SOX9, NUMB, ASCL1, GPSM2 |
GO:0060491 | BP | regulation of cell projection assembly | Any process that modulates the rate, frequency, or extent of cell projection assembly. |
FAM110C |
GO:0060492 | BP | lung induction | The close range interaction of two or more cells or tissues that causes the cells of the foregut to change their fates and specify the development of the lung. |
WNT2, CTNNB1, WNT2B |
GO:0060501 | BP | positive regulation of epithelial cell proliferation involved in lung morphogenesis | Any process that increases the rate or frequency of epithelial cell proliferation that results in the lung attaining its shape. |
FOXP2, WNT2, FGF7, FGFR2, CDC42, SRSF6 |
GO:0060502 | BP | epithelial cell proliferation involved in lung morphogenesis | The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the shaping of the lung. |
BMP4, MAP2K1 |
GO:0060503 | BP | bud dilation involved in lung branching | The process in which a bud in the lung increases radially. |
BMP4 |
GO:0060509 | BP | Type I pneumocyte differentiation | The process in which a relatively unspecialized cell acquires specialized features of a Type I pneumocyte. A type I pneumocyte is a flattened cell with greatly attenuated cytoplasm and a paucity of organelles. |
NFIB, THRA, CREB1, KLF2 |
GO:0060510 | BP | Type II pneumocyte differentiation | The process in which a relatively unspecialized cell acquires specialized features of a Type II pneumocyte. A Type II pneumocyte is a surfactant secreting cell that contains abundant cytoplasm containing numerous lipid-rich multilamellar bodies. |
NFIB, NKX2-1, GATA6 |
GO:0060512 | BP | prostate gland morphogenesis | The process in which the anatomical structures of a prostate gland are generated and organized. |
FGFR2, SERPINB5 |
GO:0060513 | BP | prostatic bud formation | The morphogenetic process in which a region of the fetal urogenital sinus epithelium is specified to become the prostate, resulting in prostate bud outgrowth. |
GLI2 |
GO:0060517 | BP | epithelial cell proliferation involved in prostatic bud elongation | The multiplication of epithelial cells, contributing to the expansion of the primary prostatic bud. |
SOX9 |
GO:0060520 | BP | activation of prostate induction by androgen receptor signaling pathway | Any series of molecular signals generated as a consequence of an androgen binding to its receptor in the urogenital sinus mesenchyme that initiates prostate induction. Prostate induction is the close range interaction of the urogenital sinus mesenchyme and the urogenital sinus epithelium that causes the cells of the urogenital sinus epithelium to change their fates and specify the development of the prostate gland. |
AR |
GO:0060523 | BP | prostate epithelial cord elongation | The developmental growth process in which solid chords of prostate epithelium increase in length. |
ESR1, FGFR2 |
GO:0060527 | BP | prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis | The branching morphogenesis process in which the prostate epithelial cords branch freely to create the structure of the prostate acini. |
ESR1, FGFR2, SFRP1, FRS2 |
GO:0060528 | BP | secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development | The process in which a relatively unspecialized epithelial cell acquires specialized features of a secretory columnal luminar epithelial cell of the prostate. |
NOTCH1 |
GO:0060529 | BP | squamous basal epithelial stem cell differentiation involved in prostate gland acinus development | The process in which a relatively unspecialized epithelial cell acquires specialized features of a squamous basal epithelial stem cell of the prostate. |
FGFR2 |
GO:0060532 | BP | bronchus cartilage development | The process whose specific outcome is the progression of lung cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate. |
SOX9 |
GO:0060534 | BP | trachea cartilage development | The process whose specific outcome is the progression of the tracheal cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate. |
SOX9 |
GO:0060535 | BP | trachea cartilage morphogenesis | The process in which the anatomical structures of cartilage in the trachea are generated and organized. |
LRP6 |
GO:0060536 | BP | cartilage morphogenesis | The process in which the anatomical structures of cartilage are generated and organized. |
SNAI2, MEF2C |
GO:0060538 | BP | skeletal muscle organ development | The progression of a skeletal muscle organ over time from its initial formation to its mature state. A skeletal muscle organ includes the skeletal muscle tissue and its associated connective tissue. |
LARGE |
GO:0060539 | BP | diaphragm development | The progression of the diaphragm over time from its initial formation to the mature structure. The diaphragm is a skeletal muscle that is responsible for contraction and expansion of the lungs. |
TCF21, ASS1, WT1, DISP1 |
GO:0060541 | BP | respiratory system development | The progression of the respiratory system over time from its formation to its mature structure. The respiratory system carries out respiratory gaseous exchange. |
TCF21 |
GO:0060544 | BP | regulation of necroptotic process | Any process that modulates the rate, frequency or extent of a necroptotic process, a necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors or Toll-like receptors. |
CFLAR, BIRC3 |
GO:0060545 | BP | positive regulation of necroptotic process | Any process that increases the rate, frequency or extent of a necroptotic process, a necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors or Toll-like receptors. |
RIPK1 |
GO:0060546 | BP | negative regulation of necroptotic process | Any process that decreases the rate, frequency or extent of a necroptotic process, a necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors or Toll-like receptors. |
SLC25A4, CAV1, FADD, BIRC3, ARHGEF2 |
GO:0060547 | BP | negative regulation of necrotic cell death | Any process that decreases the rate, frequency or extent of necrotic cell death. Necrotic cell death is a cell death process that is morphologically characterized by a gain in cell volume (oncosis), swelling of organelles, plasma membrane rupture and subsequent loss of intracellular contents. |
NOL3, MT3 |
GO:0060548 | BP | negative regulation of cell death | Any process that decreases the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death. |
CYR61, NPC1, CHMP2A, BNIP3L, PARK2, VPS4B, WISP2, WISP1, CST3, FGF2, HSPA1A, HSPA1B, BMP4, CTGF, ADCYAP1R1, HTR2B, SOX4, BNIP3, SRSF6, SMAD4, PRKD1, TEAD2, ADNP2, AGR3, ZFPM2, PACRG, NPAS2, CHMP4B, CACYBP, RAD18, IMPACT |
GO:0060557 | BP | positive regulation of vitamin D biosynthetic process | Any process that increases the rate, frequency or extent of a vitamin D biosynthetic process. Vitamin D biosynthesis is the chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3). |
TNF |
GO:0060558 | BP | regulation of calcidiol 1-monooxygenase activity | Any process that modulates the rate, frequency or extent of calcidiol 1-monooxygenase activity. Calcidiol 1-monooxygenase activity is catalysis of the reaction: calcidiol + NADPH + H+ + O2 = calcitriol + NADP+ + H2O. |
VDR |
GO:0060559 | BP | positive regulation of calcidiol 1-monooxygenase activity | Any process that increases the rate, frequency or extent of calcidiol 1-monooxygenase activity. Calcidiol 1-monooxygenase activity is the catalysis of the reaction: calcidiol + NADPH + H+ + O2 = calcitriol + NADP+ + H2O. |
TNF, IL1B |
GO:0060561 | BP | apoptotic process involved in morphogenesis | Any apoptotic process that contributes to the shaping of an anatomical structure. |
CRYAB, PPP2R1B |
GO:0060562 | BP | epithelial tube morphogenesis | The process in which the anatomical structures of a tube are generated and organized from an epithelium. Epithelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system. |
PRKX |
GO:0060563 | BP | neuroepithelial cell differentiation | The process in which epiblast cells acquire specialized features of neuroepithelial cells. |
CDH2, SOX4, B9D1 |
GO:0060566 | BP | positive regulation of DNA-templated transcription, termination | Any process that increases the rate, frequency or extent of DNA-templated transcription termination, the process in which transcription is completed; the formation of phosphodiester bonds ceases, the RNA-DNA hybrid dissociates, and RNA polymerase releases the DNA. |
SETX |
GO:0060571 | BP | morphogenesis of an epithelial fold | The morphogenetic process in which an epithelial sheet bends along a linear axis. |
EGFR, AR |
GO:0060574 | BP | intestinal epithelial cell maturation | The developmental process, independent of morphogenetic (shape) change, that is required for a columna/cuboidal epithelial cell of the intestine to attain its fully functional state. A columnar/cuboidal epithelial cell of the intestine mature as they migrate from the intestinal crypt to the villus. |
TYMS, CDKN1A, HIF1A |
GO:0060575 | BP | intestinal epithelial cell differentiation | The process in which a relatively unspecialized cell acquires specialized features of a columnar/cuboidal epithelial cell of the intestine. |
GATA4, GATA6 |
GO:0060576 | BP | intestinal epithelial cell development | The process whose specific outcome is the progression of a columnar/cuboidal epithelial cell of the intestine over time, from its formation to the mature structure. |
YIPF6 |
GO:0060577 | BP | pulmonary vein morphogenesis | The process in which the anatomical structure of the pulmonary venous blood vessels are generated and organized. Pulmonary veins are blood vessels that transport blood from the lungs to the heart. |
PITX2 |
GO:0060578 | BP | superior vena cava morphogenesis | The process in which the anatomical structure of superior vena cava generated and organized. The superior vena cava is a blood vessel that transports blood from the upper body to the heart. |
PITX2 |
GO:0060579 | BP | ventral spinal cord interneuron fate commitment | The process in which the developmental fate of a cell becomes restricted such that it will develop into a ventral spinal cord interneuron. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses. |
ASCL1, DLL4 |
GO:0060585 | BP | positive regulation of prostaglandin-endoperoxide synthase activity | Any process that increases the rate, frequency or extent of prostaglandin-endoperoxide synthase activity. Prostaglandin-endoperoxide synthase activity is the catalysis of the reaction: arachidonate + donor-H2 + 2 O2 = prostaglandin H2 + acceptor + H2O. |
EDN1, EDN2 |
GO:0060586 | BP | multicellular organismal iron ion homeostasis | Any process involved in the maintenance of the distribution of iron stores within tissues and organs of a multicellular organism. |
BMP6, SLC11A1, SLC11A2, HAMP, HYAL2, HFE, BTBD9, SLC40A1 |
GO:0060587 | BP | regulation of lipoprotein lipid oxidation | Any process that modulates the rate, frequency or extent of lipoprotein lipid oxidation. Lipoprotein lipid oxidation is the modification of a lipoprotein by oxidation of the lipid group. |
LEP |
GO:0060588 | BP | negative regulation of lipoprotein lipid oxidation | Any process that decreases the rate, frequency or extent of lipoprotein lipid oxidation. Lipoprotein lipid oxidation is the modification of a lipoprotein by oxidation of the lipid group. |
APOD |
GO:0060591 | BP | chondroblast differentiation | The process in which a mesenchymal cell, acquires specialized structural and/or functional features of a chondroblast. Differentiation includes the processes involved in commitment of a cell to a chondroblast fate. A chondroblast is a precursor cell to chondrocytes. |
CYR61, FGF2, GDF5 |
GO:0060592 | BP | mammary gland formation | The process pertaining to the initial formation of the mammary gland from unspecified parts. The process begins with formation of the mammary line and ends when the solid mammary bud invades the primary mammary mesenchyme. |
BMP4 |
GO:0060594 | BP | mammary gland specification | The regionalization process in which the mammary line is specified. The mammary line is a ridge of epidermal cells that will form the mammary placodes. |
GLI3 |
GO:0060595 | BP | fibroblast growth factor receptor signaling pathway involved in mammary gland specification | The series of molecular signals initiated by binding of a fibroblast growth factor to its receptor on the surface of al cell in the epidermis resulting in the formation of the mammary line. The mammary line is a ridge of epidermal cells that will form the mammary placodes. |
FGFR2 |
GO:0060598 | BP | dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis | The process in which the terminal end of a mammary duct bifurcates. |
AREG |
GO:0060599 | BP | lateral sprouting involved in mammary gland duct morphogenesis | The process in which a branch forms along the side of a mammary duct. |
AR, WNT5A |
GO:0060601 | BP | lateral sprouting from an epithelium | The process in which a branch forms along the side of an epithelium. |
FGFR2 |
GO:0060603 | BP | mammary gland duct morphogenesis | The process in which anatomical structures of the mammary ducts are generated and organized. Mammary ducts are epithelial tubes that transport milk. |
CSF1R, GLI2, PTCH1 |