| GO ID | Ontology | GO Term | Term Definition |
Proteins |
GO:0004021 | MF | L-alanine:2-oxoglutarate aminotransferase activity | Catalysis of the reaction: 2-oxoglutarate + L-alanine = L-glutamate + pyruvate. |
GPT2 |
GO:0004022 | MF | alcohol dehydrogenase (NAD) activity | Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+. |
ADH7, DHRS9 |
GO:0004024 | MF | alcohol dehydrogenase activity, zinc-dependent | Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+, requiring the presence of zinc. |
ADH1B, ADH7 |
GO:0004028 | MF | 3-chloroallyl aldehyde dehydrogenase activity | Catalysis of the reaction: 3-chloroallyl aldehyde + H2O = 2 H+ + 2 e- + 3-chloroacrylic acid. |
ALDH1A2, ALDH3B2, ALDH9A1, ALDH3A2 |
GO:0004029 | MF | aldehyde dehydrogenase (NAD) activity | Catalysis of the reaction: an aldehyde + NAD+ + H2O = an acid + NADH + H+. |
ALDH1L1, ALDH1A2, ALDH1A1, ALDH2, ALDH1B1, ALDH1A3, ALDH3B2, ALDH9A1, ALDH7A1, ALDH3A2, ALDH6A1, ALDH1L2, ALDH8A1 |
GO:0004030 | MF | aldehyde dehydrogenase [NAD(P)+] activity | Catalysis of the reaction: an aldehyde + NAD(P)+ + H2O = an acid + NAD(P)H + H+. |
ALDH2, ALDH1A3, ALDH3B2, ALDH3A2 |
GO:0004031 | MF | aldehyde oxidase activity | Catalysis of the reaction: an aldehyde + H2O + O2 = a carboxylic acid + hydrogen peroxide. |
ADH7, AOX1 |
GO:0004032 | MF | alditol:NADP+ 1-oxidoreductase activity | Catalysis of the reaction: an alditol + NADP+ = an aldose + NADPH + H+. |
AKR7A2, AKR1B1, AKR1C3, AKR1C2, AKR1C1 |
GO:0004033 | MF | aldo-keto reductase (NADP) activity | Catalysis of the reaction: an alcohol + NADP+ = an aldehyde or a ketone + NADPH + H+. |
AKR7A2, CYB5A, AKR1B1, AKR1C3, AKR1C1, MIOX |
GO:0004035 | MF | alkaline phosphatase activity | Catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum. |
ALPL |
GO:0004043 | MF | L-aminoadipate-semialdehyde dehydrogenase activity | Catalysis of the reaction: L-2-aminoadipate 6-semialdehyde + NADP+ + H2O = L-2-aminoadipate + NADPH + H+. |
ALDH7A1 |
GO:0004044 | MF | amidophosphoribosyltransferase activity | Catalysis of the reaction: 5-phospho-beta-D-ribosylamine + L-glutamate + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + L-glutamine + H(2)O. |
PPAT |
GO:0004045 | MF | aminoacyl-tRNA hydrolase activity | Catalysis of the reaction: N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA. |
ICT1, PTRHD1, C12orf65 |
GO:0004046 | MF | aminoacylase activity | Catalysis of the reaction: an N-acyl-L-amino acid + H2O = a carboxylate + an L-amino acid. |
DARS |
GO:0004047 | MF | aminomethyltransferase activity | Catalysis of the reaction: (6S)-tetrahydrofolate + S-aminomethyldihydrolipoylprotein = (6R)-5,10-methylenetetrahydrofolate + NH3 + dihydrolipoylprotein. |
GCSH |
GO:0004051 | MF | arachidonate 5-lipoxygenase activity | Catalysis of the reaction: arachidonate + O2 = (6E,8Z,11Z,14Z)-(5S)-5-hydroperoxycosa-6,8,11,14-tetraenoate. |
ALOX5 |
GO:0004052 | MF | arachidonate 12-lipoxygenase activity | Catalysis of the reaction: arachidonate + O(2) = (5Z,8Z,10E,12S,14Z)-12-hydroperoxyicosa-5,8,10,14-tetraenoate. |
ALOX15 |
GO:0004055 | MF | argininosuccinate synthase activity | Catalysis of the reaction: ATP + L-citrulline + L-aspartate = AMP + diphosphate + (N(omega)-L-arginino)succinate. |
ASS1 |
GO:0004062 | MF | aryl sulfotransferase activity | Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + a phenol = adenosine 3',5'-bisphosphate + an aryl sulfate. |
SULT1A3, SULT2A1 |
GO:0004063 | MF | aryldialkylphosphatase activity | Catalysis of the reaction: aryl dialkyl phosphate + H2O = dialkyl phosphate + an aryl alcohol. |
PON1 |
GO:0004064 | MF | arylesterase activity | Catalysis of the reaction: a phenyl acetate + H2O = a phenol + acetate. |
CA2, PON1, APMAP |
GO:0004065 | MF | arylsulfatase activity | Catalysis of the reaction: a phenol sulfate + H2O = a phenol + sulfate. |
ARSA, ARSB, ARSD, ARSK, SULF2, SULF1 |
GO:0004066 | MF | asparagine synthase (glutamine-hydrolyzing) activity | Catalysis of the reaction: ATP + L-aspartate + L-glutamine = AMP + diphosphate + L-asparagine + L-glutamate. |
ASNS |
GO:0004067 | MF | asparaginase activity | Catalysis of the reaction: L-asparagine + H2O = L-aspartate + NH3. |
ASRGL1 |
GO:0004069 | MF | L-aspartate:2-oxoglutarate aminotransferase activity | Catalysis of the reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate. |
GOT2 |
GO:0004070 | MF | aspartate carbamoyltransferase activity | Catalysis of the reaction: L-aspartate + carbamoyl phosphate = N-carbamoyl-L-aspartate + H(+) + phosphate. |
CAD |
GO:0004074 | MF | biliverdin reductase activity | Catalysis of the reaction: bilirubin + NAD(P)+ = biliverdin + NAD(P)H + H+. |
BLVRB |
GO:0004075 | MF | biotin carboxylase activity | Catalysis of the reaction: ATP + biotin-carboxyl-carrier protein + CO2 = ADP + phosphate + carboxybiotin-carboxyl-carrier protein. |
ACACB, PCCA, PC, MCCC1 |
GO:0004082 | MF | bisphosphoglycerate mutase activity | Catalysis of the reaction: 3-phospho-D-glyceroyl phosphate = 2,3-bisphospho-D-glycerate. |
BPGM, PGAM1 |
GO:0004083 | MF | bisphosphoglycerate 2-phosphatase activity | Catalysis of the reaction: 2,3-bisphospho-D-glycerate + H(2)O = 3-phospho-D-glycerate + phosphate. |
BPGM, PGAM1 |
GO:0004084 | MF | branched-chain-amino-acid transaminase activity | Catalysis of the reaction: a branched-chain amino acid + 2-oxoglutarate = L-glutamate + a 2-oxocarboxylate derived from the branched-chain amino acid. |
BCAT1 |
GO:0004087 | MF | carbamoyl-phosphate synthase (ammonia) activity | Catalysis of the reaction: 2 ATP + CO(2) + H(2)O + NH(4)(+) = 2 ADP + carbamoyl phosphate + 5 H(+) + phosphate. |
CAD |
GO:0004088 | MF | carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity | Catalysis of the reaction: 2 ATP + L-glutamine + CO2 + H2O = 2 ADP + phosphate + glutamate + carbamoyl phosphate. |
CAD |
GO:0004089 | MF | carbonate dehydratase activity | Catalysis of the reaction: H2CO3 = CO2 + H2O. |
CA12, CA2, CA3, CA4, CA8, CA13 |
GO:0004090 | MF | carbonyl reductase (NADPH) activity | Catalysis of the reaction: R-CHOH-R' + NADP+ = R-CO-R' + NADPH + H+. |
CBR1, DHRS4 |
GO:0004092 | MF | carnitine O-acetyltransferase activity | Catalysis of the reaction: acetyl-CoA + carnitine = (R)-O-acetylcarnitine + CoA. |
CRAT |
GO:0004095 | MF | carnitine O-palmitoyltransferase activity | Catalysis of the reaction: palmitoyl-CoA + L-carnitine = CoA + L-palmitoylcarnitine. |
CPT1A, CPT1B |
GO:0004096 | MF | catalase activity | Catalysis of the reaction: 2 hydrogen peroxide = O2 + 2 H2O. |
CYGB, GPX7 |
GO:0004098 | MF | cerebroside-sulfatase activity | Catalysis of the reaction: a cerebroside 3-sulfate + H2O = a cerebroside + sulfate. |
ARSA |
GO:0004103 | MF | choline kinase activity | Catalysis of the reaction: ATP + choline = ADP + choline phosphate + 2 H(+). |
CHKA, CHKB |
GO:0004104 | MF | cholinesterase activity | Catalysis of the reaction: an acylcholine + H2O = choline + a carboxylic acid anion. |
CHKA |
GO:0004105 | MF | choline-phosphate cytidylyltransferase activity | Catalysis of the reaction: CTP + choline phosphate = diphosphate + CDP-choline. |
PCYT1A, PCYT1B |
GO:0004109 | MF | coproporphyrinogen oxidase activity | Catalysis of the reaction: coproporphyrinogen III + 2 H(+) + O(2) = 2 CO(2) + 2 H(2)O + protoporphyrinogen IX. |
CPOX |
GO:0004111 | MF | creatine kinase activity | Catalysis of the reaction: ATP + creatine = N-phosphocreatine + ADP + 2 H(+). |
MAP4K4, CKB, CKMT1A, CKMT2 |
GO:0004113 | MF | 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity | Catalysis of the reaction: nucleoside 2',3'-cyclic phosphate + H2O = nucleoside 2'-phosphate. |
CNP |
GO:0004114 | MF | 3',5'-cyclic-nucleotide phosphodiesterase activity | Catalysis of the reaction: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate. |
PDE6D, PDE8A, PDE5A, PDE9A, PDE8B, PDE4D, PDE3B |
GO:0004115 | MF | 3',5'-cyclic-AMP phosphodiesterase activity | Catalysis of the reaction: adenosine 3',5'-cyclic phosphate + H2O = adenosine 5'-phosphate. |
PDE8A, PDE8B, PDE4C, PDE4D, PDE3B, PDE7A, PDE3A, PDE7B |
GO:0004119 | MF | cGMP-inhibited cyclic-nucleotide phosphodiesterase activity | Catalysis of the reaction: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate; catalytic activity is decreased in the presence of cGMP. |
PDE3B, PDE3A |
GO:0004122 | MF | cystathionine beta-synthase activity | Catalysis of the reaction: L-serine + L-homocysteine = cystathionine + H2O. |
CBS |
GO:0004123 | MF | cystathionine gamma-lyase activity | Catalysis of the reaction: L-cystathionine + H2O = 2-oxobutanoate + L-cysteine + NH4+. |
CTH |
GO:0004124 | MF | cysteine synthase activity | Catalysis of the reaction: O3-acetyl-L-serine + hydrogen sulfide = L-cysteine + acetate. |
CBS |
GO:0004126 | MF | cytidine deaminase activity | Catalysis of the reaction: cytidine + H2O = uridine + NH3. |
APOBEC3G |
GO:0004127 | MF | cytidylate kinase activity | Catalysis of the reaction: ATP + (d)CMP = ADP + (d)CDP. |
CMPK1, CMPK2, AK8 |
GO:0004128 | MF | cytochrome-b5 reductase activity, acting on NAD(P)H | Catalysis of the reaction: NAD(P)H + H+ + 2 ferricytochrome b(5) = NAD(P)+ + 2 ferrocytochrome b(5). |
CYB5R3, NQO1 |
GO:0004129 | MF | cytochrome-c oxidase activity | Catalysis of the reaction: 4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O. |
NDUFA4, CYB5A, COX6C, COX5B, COX6A1, COX6B1, COX7C, COX5A, COX7B, COX7B2, NMES1, COX11 |
GO:0004132 | MF | dCMP deaminase activity | Catalysis of the reaction: dCMP + H2O = dUMP + NH3. |
DCTD |
GO:0004133 | MF | glycogen debranching enzyme activity | Catalysis of the cleavage of branch points in branched glycogen polymers. |
AGL |
GO:0004134 | MF | 4-alpha-glucanotransferase activity | Catalysis of the transfer of a segment of a (1->4)-alpha-D-glucan to a new 4-position in an acceptor, which may be glucose or (1->4)-alpha-D-glucan. |
AGL |
GO:0004135 | MF | amylo-alpha-1,6-glucosidase activity | Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic branch linkages in glycogen phosphorylase limit dextrin. Limit dextrin is the highly branched core that remains after exhaustive treatment of glycogen with glycogen phosphorylase. It is formed because these enzymes cannot hydrolyze the (1->6) glycosidic linkages present. |
AGL |
GO:0004137 | MF | deoxycytidine kinase activity | Catalysis of the reaction: NTP + deoxycytidine = NDP + CMP. |
TK2, DCK |
GO:0004138 | MF | deoxyguanosine kinase activity | Catalysis of the reaction: 2'-deoxyguanosine + ATP = ADP + dGMP + 2 H(+). |
DGUOK |
GO:0004139 | MF | deoxyribose-phosphate aldolase activity | Catalysis of the reaction: 2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde. |
DERA |
GO:0004140 | MF | dephospho-CoA kinase activity | Catalysis of the reaction: 3'-dephospho-CoA + ATP = ADP + CoA + 2 H(+). |
COASY, DCAKD |
GO:0004142 | MF | diacylglycerol cholinephosphotransferase activity | Catalysis of the reaction: CDP-choline + 1,2-diacylglycerol = CMP + a phosphatidylcholine. |
CDS1, CEPT1 |
GO:0004143 | MF | diacylglycerol kinase activity | Catalysis of the reaction: NTP + 1,2-diacylglycerol = NDP + 1,2-diacylglycerol-3-phosphate. |
DGKZ, DGKK, DGKH |
GO:0004144 | MF | diacylglycerol O-acyltransferase activity | Catalysis of the reaction: acyl-CoA + 1,2-diacylglycerol = CoA + triacylglycerol. |
DGAT2 |
GO:0004145 | MF | diamine N-acetyltransferase activity | Catalysis of the reaction: acetyl-CoA + an alkane-alpha,omega-diamine = CoA + an N-acetyldiamine. |
SAT1, SAT2 |
GO:0004146 | MF | dihydrofolate reductase activity | Catalysis of the reaction: 5,6,7,8-tetrahydrofolate + NADP+ = 7,8-dihydrofolate + NADPH + H+. |
DHFR |
GO:0004148 | MF | dihydrolipoyl dehydrogenase activity | Catalysis of the reaction: protein N6-(dihydrolipoyl)lysine + NAD+ = protein N6-(lipoyl)lysine + NADH + H+. |
DLD |
GO:0004149 | MF | dihydrolipoyllysine-residue succinyltransferase activity | Catalysis of the reaction: succinyl-CoA + dihydrolipoamide = CoA + S-succinyldihydrolipoamide. |
DLST |
GO:0004151 | MF | dihydroorotase activity | Catalysis of the reaction: (S)-dihydroorotate + H(2)O = N-carbamoyl-L-aspartate + H(+). |
CAD |
GO:0004152 | MF | dihydroorotate dehydrogenase activity | Catalysis of the reaction: (S)-dihydroorotate + A = AH(2) + orotate. |
DHODH |
GO:0004155 | MF | 6,7-dihydropteridine reductase activity | Catalysis of the reaction: NADP+ + 5,6,7,8-tetrahydropteridine = NADPH + H+ + 6,7-dihydropteridine. |
QDPR |
GO:0004157 | MF | dihydropyrimidinase activity | Catalysis of the reaction: 5,6-dihydrouracil + H2O = 3-ureidopropionate. |
DPYSL2 |
GO:0004161 | MF | dimethylallyltranstransferase activity | Catalysis of the reaction: dimethylallyl diphosphate + isopentenyl diphosphate = diphosphate + geranyl diphosphate. |
FDPS |
GO:0004163 | MF | diphosphomevalonate decarboxylase activity | Catalysis of the reaction: (R)-5-diphosphomevalonate + ATP = ADP + CO(2) + H(+) + isopentenyl diphosphate + phosphate. |
MVD |
GO:0004164 | MF | diphthine synthase activity | Catalysis of the reaction: S-adenosyl-L-methionine + 2-(3-carboxy-3-aminopropyl)-L-histidine = S-adenosyl-L-homocysteine + 2-(3-carboxy-3-(methylammonio)propyl)-L-histidine. |
DPH5 |
GO:0004165 | MF | dodecenoyl-CoA delta-isomerase activity | Catalysis of the reaction: 3-cis-dodecenoyl-CoA = 2-trans-dodecenoyl-CoA. |
ECI2, ECI1 |
GO:0004167 | MF | dopachrome isomerase activity | Catalysis of the reaction: L-dopachrome = 5,6-dihydroxyindole-2-carboxylate. |
MIF, DDT |
GO:0004169 | MF | dolichyl-phosphate-mannose-protein mannosyltransferase activity | Catalysis of the reaction: dolichyl phosphate D-mannose + protein = dolichyl phosphate + O-D-mannosylprotein. |
SDF2, POMT1 |
GO:0004170 | MF | dUTP diphosphatase activity | Catalysis of the reaction: dUTP + H2O = dUMP + diphosphate. |
DUT |
GO:0004174 | MF | electron-transferring-flavoprotein dehydrogenase activity | Catalysis of the reaction: reduced ETF + ubiquinone = ETF + ubiquinol. |
ETFDH, AIFM2 |
GO:0004175 | MF | endopeptidase activity | Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain. |
ADAM10, TPP1, MMP1, KLK3, MME, CTSH, FURIN, ACE, MMP9, PCSK6, TPP2, CASP1, ECE1, PSEN1, PSEN2, HTRA3, PSMD2, FAM76B, ERAP2, TRABD2A, FAM76A, APH1B, APH1A, SENP5, TMEM59, SENP3, ERAP1, RCE1 |
GO:0004176 | MF | ATP-dependent peptidase activity | Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the hydrolysis of peptide bonds. |
CLPX, LONRF1, LONRF2, LONRF3, LONP2, YME1L1 |
GO:0004177 | MF | aminopeptidase activity | Catalysis of the hydrolysis of N-terminal amino acid residues from in a polypeptide chain. |
CTSH, LAP3, TPP2, METAP2, NPEPPS, BLMH, ERAP2, AOPEP, XPNPEP3, ERAP1, LNPEP |
GO:0004180 | MF | carboxypeptidase activity | Catalysis of the hydrolysis of the terminal or penultimate peptide bond at the C-terminal end of a peptide or polypeptide. |
ACE, CPM, CPE, BLMH, AEBP1, CPQ |
GO:0004181 | MF | metallocarboxypeptidase activity | Catalysis of the hydrolysis of C-terminal amino acid residues from a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions. |
CPM, CPN1, CPE, CPZ, AEBP1, CPB2, AGBL1, AGTPBP1 |
GO:0004185 | MF | serine-type carboxypeptidase activity | Catalysis of the hydrolysis of a peptide bond not more than three residues from the C-terminus of a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine). |
CPM, CPN1, CPE, CPZ, AEBP1, SCPEP1 |
GO:0004190 | MF | aspartic-type endopeptidase activity | Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which a water molecule bound by the side chains of aspartic residues at the active center acts as a nucleophile. |
CTSD, PSEN1, PSEN2, NRIP3 |
GO:0004197 | MF | cysteine-type endopeptidase activity | Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile. |
USP12, USP2, USP1, CTSD, CTSL, CTSB, CTSH, UCHL1, CTSS, CASP1, PDIA3, USP6, CTSK, USP11, CTSC, CASP9, CASP6, BLMH, ESPL1, CASP8, USP34, SFRP1, USP13, CTSZ, CTSF, RCE1, USP20, USP15 |
GO:0004198 | MF | calcium-dependent cysteine-type endopeptidase activity | Catalysis of the hydrolysis of nonterminal peptide bonds in a polypeptide chain by a mechanism using a cysteine residue at the enzyme active center, and requiring the presence of calcium. |
CAPN5, PDCD6, CAPN15, CAPN3, SRI, CAPN10 |
GO:0004222 | MF | metalloendopeptidase activity | Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions. |
ADAM10, ADAM12, NRDC, ADAM23, PMPCB, PAPLN, ECEL1, MMP1, MMP2, MME, MMP10, BMP1, IDE, MMP9, UQCRC2, MMP8, MMP11, UQCRC1, ECE1, MMP14, MMP15, MMP16, THOP1, ADAMTS12, YBEY, ADAMTS20, ADAM8, ADAM17, PMPCA, PAPPA, ADAM9, CLCA4, MMEL1, PITRM1, ADAMTSL4, THSD4, TRABD2A, ADAMTS17, ADAMTS15, ADAMTS18, OMA1, YME1L1, MMP19, MIPEP, NLN, ADAM19, ADAMTS10, MMP25, MMP26, ADAMTS9, ADAMTS1, ADAM21, ADAMTS7, ADAMTS6, ADAMTS5, ADAMTS8, RCE1, MMP24, XRCC6BP1 |
GO:0004252 | MF | serine-type endopeptidase activity | Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine). |
MASP2, TPP1, KLK10, PRSS23, F8, F2, C1R, PLG, PLAU, PLAT, CFB, C3, C1QA, MMP1, CFI, KLK3, CTSD, PRSS1, CTSL, CTSB, CELA2A, CELA2B, MMP2, MMP10, CTSH, C1S, FURIN, C4A, C4B, MBL2, F5, BMP1, MMP9, KLK2, MMP8, MMP11, CTSS, MST1, DPP4, PCSK1, PCSK6, TPP2, PRSS3, CTSK, PREP, MMP14, MMP15, CTSC, PRSS12, ADAM8, HTRA3, FCN2, CLPP, MST1L, PREPL, CTRB2, RHBDD2, LONP2, TMPRSS6, PCSK9, RHBDD1, HTRA1, PCSK5, MMP19, C1RL |
GO:0004298 | MF | threonine-type endopeptidase activity | Catalysis of the hydrolysis of internal peptide bonds in a polypeptide chain by a mechanism in which the hydroxyl group of a threonine residue at the active center acts as a nucleophile. |
PSMB1, PSMA1, PSMA2, PSMA3, PSMA4, PSMB8, PSMB9, PSMB4, PSMB5, PSMB10, PSMB3 |
GO:0004300 | MF | enoyl-CoA hydratase activity | Catalysis of the reaction: (3S)-3-hydroxyacyl-CoA = trans-2-enoyl-CoA + H2O. |
ECHS1, HADHB, AUH, ECHDC2 |
GO:0004301 | MF | epoxide hydrolase activity | Catalysis of the reaction: an epoxide + H2O = a glycol. |
EPHX1 |
GO:0004303 | MF | estradiol 17-beta-dehydrogenase activity | Catalysis of the reaction: estradiol-17-beta + NADP+ = estrone + NADPH + H+. |
HSD17B6, HSD17B1, HSD17B2, HSD17B7, HSD17B12, HSD17B11 |
GO:0004304 | MF | estrone sulfotransferase activity | Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + estrone = adenosine 3',5'-bisphosphate + estrone 3-sulfate. |
SULT2A1 |
GO:0004305 | MF | ethanolamine kinase activity | Catalysis of the reaction: ATP + ethanolamine = ADP + 2 H(+) + phosphoethanolamine. |
CHKA, ETNK1, CHKB |
GO:0004306 | MF | ethanolamine-phosphate cytidylyltransferase activity | Catalysis of the reaction: CTP + ethanolamine phosphate = diphosphate + CDP-ethanolamine. |
PCYT2 |