| GO ID | Ontology | GO Term | Term Definition |
Proteins |
GO:0071208 | MF | histone pre-mRNA DCP binding | Interacting selectively and non-covalently with the downstream cleavage product (DCP) generated by histone pre-mRNA 3'-end processing. |
SNRPB, SNRPD3, SLBP |
GO:0071209 | MF | U7 snRNA binding | Interacting selectively and non-covalently with the U7 small nuclear RNA (U7 snRNA). |
SNRPD3 |
GO:0071253 | MF | connexin binding | Interacting selectively and non-covalently with a connexin, any of a group of related proteins that assemble to form gap junctions. |
GJA1, GJA5, CXADR, CNST |
GO:0071424 | MF | rRNA (cytosine-N4-)-methyltransferase activity | Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N4-methylcytosine. |
METTL15 |
GO:0071532 | MF | ankyrin repeat binding | Interacting selectively and non-covalently with an ankyrin repeat of a protein. Ankyrin repeats are tandemly repeated modules of about 33 amino acids; each repeat folds into a helix-loop-helix structure with a beta-hairpin/loop region projecting out from the helices at a 90-degree angle, and repeats stack to form an L-shaped structure. |
RELA |
GO:0071535 | MF | RING-like zinc finger domain binding | Interacting selectively and non-covalently with a RING-like zinc finger domain domain of a protein. The RING-like domain is a zinc finger domain that is related to the C3HC4 RING finger domain. |
UBE2I |
GO:0071558 | MF | histone demethylase activity (H3-K27 specific) | Catalysis of the removal of a methyl group from lysine at position 27 of the histone H3 protein. |
UTY, KDM6A, KDM7A |
GO:0071566 | MF | UFM1 activating enzyme activity | Catalysis of the activation of the small ubiquitin-related modifier UFM1, through the formation of an ATP-dependent high-energy thiolester bond. |
UBA5 |
GO:0071567 | MF | UFM1 hydrolase activity | Catalysis of the hydrolysis of UFM1, a small ubiquitin-related modifier, from previously modified substrates. |
UFSP2 |
GO:0071723 | MF | lipopeptide binding | Interacting selectively and non-covalently with a lipopeptide, any of a group of organic compounds comprising two or more amino acids linked by peptide bonds and containing a nonprotein group consisting of a lipid or lipids. |
CD1D, TLR1 |
GO:0071813 | MF | lipoprotein particle binding | Interacting selectively and non-covalently with a lipoprotein particle. A lipoprotein particle, also known as a lipoprotein, is a clathrate complex consisting of a lipid enwrapped in a protein host without covalent binding in such a way that the complex has a hydrophilic outer surface consisting of all the protein and the polar ends of any phospholipids. |
APOE, MAPT, CD36, CDH13 |
GO:0071820 | MF | N-box binding | Interacting selectively and non-covalently with an N-box, a DNA motif with the consensus sequence CACNAG that is found in the promoters of genes expressed preferentially at synapses. |
HES1 |
GO:0071837 | MF | HMG box domain binding | Interacting selectively and non-covalently with an HMG box domain, a protein domain that consists of three helices in an irregular array. HMG-box domains are found in one or more copies in HMG-box proteins, which form a large, diverse family involved in the regulation of DNA-dependent processes such as transcription, replication, and strand repair, all of which require the bending and unwinding of chromatin. |
HOXA3, JUN, HOXC4, EGR2, MEOX1, DLX5, HHEX, MEF2C, TCF12 |
GO:0071862 | MF | protein phosphatase type 1 activator activity | Increases the activity of the enzyme protein phosphatase type 1. |
PPP1R15A, PHACTR4 |
GO:0071884 | MF | vitamin D receptor activator activity | Interacting (directly or indirectly) with vitamin D receptors such that the proportion of receptors in the active form is increased. |
BAZ1B |
GO:0071886 | MF | 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding | Interacting selectively and non-covalently with the amine 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine, a serotonin receptor agonist that can act as a psychedelic drug. |
HTR2C |
GO:0071889 | MF | 14-3-3 protein binding | Interacting selectively and non-covalently with a 14-3-3 protein. A 14-3-3 protein is any of a large family of approximately 30kDa acidic proteins which exist primarily as homo- and heterodimers within all eukaryotic cells, and have been implicated in the modulation of distinct biological processes by binding to specific phosphorylated sites on diverse target proteins, thereby forcing conformational changes or influencing interactions between their targets and other molecules. Each 14-3-3 protein sequence can be roughly divided into three sections: a divergent amino terminus, the conserved core region and a divergent carboxyl terminus. The conserved middle core region of the 14-3-3s encodes an amphipathic groove that forms the main functional domain, a cradle for interacting with client proteins. |
PPP1R12A, ZFP36, AKT1, SIK1, SRPK2, ZFP36L1, HDAC7, BAD, KIF13B, DDIT4, PI4KB, SYNPO2, IRS2 |
GO:0071933 | MF | Arp2/3 complex binding | Interacting selectively and non-covalently with an Arp2/3 complex, a protein complex that contains two actin-related proteins, Arp2 and Arp3, and five novel proteins (ARPC1-5). |
IQGAP2, CORO1B, SNX9 |
GO:0071936 | MF | coreceptor activity involved in Wnt signaling pathway | In cooperation with a primary Wnt receptor, initiating a change in cell activity through the Wnt signaling pathway. |
LRP5, LRP6 |
GO:0071949 | MF | FAD binding | Interacting selectively and non-covalently with the oxidized form, FAD, of flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes. |
AGPS, KMO, PRODH, MICAL2, AIFM1, MICAL1 |
GO:0071987 | MF | WD40-repeat domain binding | Interacting selectively and non-covalently with a WD40 repeat domain of a protein. The WD40 repeat is a short structural motif of approximately 40 amino acids, often terminating in a tryptophan-aspartic acid (W-D) dipeptide. Several of these repeats are combined to form a type of protein domain called the WD domain. |
CCT6A, CDC5L |
GO:0072320 | MF | volume-sensitive chloride channel activity | Enables the transmembrane transfer of a chloride ion by a volume-sensitive channel. A volume-sensitive channel is a channel that responds to changes in the volume of a cell. |
CLCN3, TTYH1 |
GO:0072341 | MF | modified amino acid binding | Interacting selectively and non-covalently with a modified amino acid. |
CBS, MTHFR, NOX4 |
GO:0072345 | MF | NAADP-sensitive calcium-release channel activity | Enables the transmembrane transfer of a calcium ion by a channel that opens when nicotinic acid adenine dinucleotide phosphate (NAADP) has been bound by the channel complex or one of its constituent parts. |
TPCN2 |
GO:0072354 | MF | histone kinase activity (H3-T3 specific) | Catalysis of the transfer of a phosphate group to the threonine-3 residue of the N-terminal tail of histone H3. |
GSG2, VRK1 |
GO:0072518 | MF | Rho-dependent protein serine/threonine kinase activity | Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires binding of the GTPase Rho. |
ROCK2 |
GO:0072542 | MF | protein phosphatase activator activity | Increases the activity of a protein phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a protein substrate molecule. |
CALM2 |
GO:0072572 | MF | poly-ADP-D-ribose binding | Interacting selectively and non-covalently with polymeric ADP-D-ribose, a polymer that is composed of poly-ADP-D-ribose units linked through 1,2-glycosidic bonds at the ribose ring. |
RNF146 |
GO:0072590 | MF | N-acetyl-L-aspartate-L-glutamate ligase activity | Catalysis of the reaction: ATP + N-acetyl-L-aspartate + L-glutamate = ADP + phosphate + N-acetylaspartyl-glutamate. |
RIMKLB |
GO:0072591 | MF | citrate-L-glutamate ligase activity | Catalysis of the reaction: ATP + citrate + L-glutamate = ADP + phosphate + beta-citryl-L-glutamate. |
RIMKLB |
GO:0080019 | MF | fatty-acyl-CoA reductase (alcohol-forming) activity | Catalysis of the reaction: a very long chain fatty acyl-CoA + NADPH + H+ = a very long chain primary alcohol + NADP+ + CoA. |
FAR2 |
GO:0080023 | MF | 3R-hydroxyacyl-CoA dehydratase activity | Catalysis of the reaction: 3R-hydroxyacyl-CoA = 2E-enoyl-CoA + H2O. |
HACD1, HACD2 |
GO:0080025 | MF | phosphatidylinositol-3,5-bisphosphate binding | Interacting selectively and non-covalently with phosphatidylinositol-3,5-bisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3' and 5' positions. |
SH3PXD2B, SNX3, WIPI1, COMMD1, GBF1, MAPKAP1, PLEKHA5, ATP13A2, WDR45, WIPI2 |
GO:0080101 | MF | phosphatidyl-N-dimethylethanolamine N-methyltransferase activity | Catalysis of the reaction: S-adenosyl-L-methionine + phosphatidyl-N-dimethylethanolamine = S-adenosyl-L-homocysteine + phosphatidylcholine. |
PEMT |
GO:0080122 | MF | AMP transmembrane transporter activity | Enables the transfer of AMP, adenosine monophosphate, from one side of a membrane to the other. |
SLC25A17 |
GO:0080130 | MF | L-phenylalanine:2-oxoglutarate aminotransferase activity | Catalysis of the reaction: L-phenylalanine + 2-oxoglutarate = phenylpyruvate + L-glutamate. |
GOT2 |
GO:0080132 | MF | fatty acid alpha-hydroxylase activity | Catalysis of the conversion of a fatty acid to an alpha-hydroxylated fatty acid. A hydroxyl group is added to the second carbon, counted from the carboxyl end, of a fatty acid chain. |
FA2H |
GO:0080146 | MF | L-cysteine desulfhydrase activity | Catalysis of the reaction: L-cysteine + H2O = ammonia + pyruvate + hydrogen sulfide + H+. |
CTH |
GO:0086007 | MF | voltage-gated calcium channel activity involved in cardiac muscle cell action potential | Enables the transmembrane transfer of a calcium ion by a voltage-gated channel across the plasma membrane of a cardiac muscle cell that contributes to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. |
CACNA2D1, CACNA1C |
GO:0086008 | MF | voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization | Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of a cardiac muscle cell contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. |
KCNH2 |
GO:0086039 | MF | calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential | Catalysis of the transfer of a solute or solutes from one side of a cardiac muscle cell plasma membrane to the other according to the reaction: ATP + H2O + Ca2+(cis) = ADP + phosphate + Ca2+(trans). The transfer contributes to the regulation of the plasma membrane potential. |
ATP2A2 |
GO:0086056 | MF | voltage-gated calcium channel activity involved in AV node cell action potential | Enables the transmembrane transfer of a calcium ion by a voltage-gated channel across the plasma membrane of an AV node cardiac muscle cell that contributes to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. |
CACNA1G, CACNA1C |
GO:0086059 | MF | voltage-gated calcium channel activity involved SA node cell action potential | Enables the transmembrane transfer of a calcium ion by a voltage-gated channel across the plasma membrane of an SA node cardiac muscle cell that contributes to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. |
CACNA1G |
GO:0086075 | MF | gap junction channel activity involved in cardiac conduction electrical coupling | A wide pore channel activity that enables a direct cytoplasmic connection from one cardiomyocyte to an adjacent cardiomyocyte. The gap junction passes electrical signals between the cells contributing to cardiac conduction. |
GJA1, GJA5 |
GO:0086077 | MF | gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling | A wide pore channel activity that enables a direct cytoplasmic connection from an AV node cell to a bundle of His cell. The gap junction passes electrical signals between the cells contributing to cardiac conduction. |
GJA5 |
GO:0086080 | MF | protein binding involved in heterotypic cell-cell adhesion | Interacting selectively and non-covalently with any protein or protein complex contributing to the adhesion of two different types of cells. |
GLDN, NRCAM |
GO:0086083 | MF | cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication | Interacting selectively and non-covalently with any protein or protein complex that results in the connection of a bundle of His cell with a Purkinje myocyte and contributes to the communication between the two cells. |
JUP, DSP, DSC2, DSG2, PKP2 |
GO:0089720 | MF | caspase binding | Interacting selectively and non-covalently with a caspase family protein. |
NOL3, FADD |
GO:0090450 | MF | inosine-diphosphatase activity | Catalysis of the reaction: IDP + H2O = IMP + phosphate. |
NUDT16 |
GO:0090541 | MF | MIT domain binding | Interacting selectively and non-covalently with the MIT domain of a protein. The MIT domain is found in vacuolar sorting proteins, spastin (probable ATPase involved in the assembly or function of nuclear protein complexes), and a sorting nexin, which may play a role in intracellular trafficking. |
IST1 |
GO:0090554 | MF | phosphatidylcholine-translocating ATPase activity | Catalysis of the movement of phosphatidylcholine from one membrane bilayer leaflet to the other, driven by the hydrolysis of ATP. |
ABCA1 |
GO:0090556 | MF | phosphatidylserine-translocating ATPase activity | Catalysis of the movement of phosphatidylserine from one membrane bilayer leaflet to the other, driven by the hydrolysis of ATP. |
ABCA1 |
GO:0090624 | MF | endoribonuclease activity, cleaving miRNA-paired mRNA | Catalysis of the endonucleolytic cleavage of the mRNA in a double-stranded RNA molecule formed by the base pairing of an mRNA with an miRNA. |
AGO2 |
GO:0097003 | MF | adipokinetic hormone receptor activity | Combining with an adipokinetic hormone to initiate a change in cell activity. Adipokinetic hormones (AKHs) are peptide hormones that are involved in the mobilization of sugar and lipids from the insect fat body during energy-requiring activities such as flight and locomotion. They also contribute to hemolymph sugar homeostasis. |
ADIPOR2, ADIPOR1 |
GO:0097016 | MF | L27 domain binding | Interacting selectively and non-covalently with a L27 domain of a protein. L27 is composed of conserved negatively charged amino acids and a conserved aromatic amino acid. L27 domains can assemble proteins involved in signaling and establishment and maintenance of cell polarity into complexes by interacting in a heterodimeric manner. |
DLG1, LIN7C |
GO:0097020 | MF | COPII adaptor activity | The binding activity of a molecule that brings together the COPII vesicle proteins and one or more other molecules, permitting them to function in a coordinated way. |
TEX261 |
GO:0097027 | MF | ubiquitin-protein transferase activator activity | Increases the activity of a ubiquitin-protein transferase, an enzyme that catalyzes the covalent attachment of ubiquitin to lysine in a substrate protein. |
RING1, CDC20, FZR1 |
GO:0097100 | MF | supercoiled DNA binding | Interacting selectively and non-covalently with supercoiled DNA. For example, during replication and transcription, template DNA is negatively supercoiled in the receding downstream DNA and positively supercoiled in the approaching downstream DNA. |
PSIP1, HMGB1, HMGB2 |
GO:0097108 | MF | hedgehog family protein binding | Interacting selectively and non-covalently with a member of the hedgehog protein family, signaling proteins involved in development. |
PTCH1, HHIP |
GO:0097109 | MF | neuroligin family protein binding | Interacting selectively and non-covalently with a member of the neuroligin protein family, neuronal cell surface proteins that mediate synapse formation. |
DLG4, NRXN1 |
GO:0097110 | MF | scaffold protein binding | Interacting selectively and non-covalently with a scaffold protein. Scaffold proteins are crucial regulators of many key signaling pathways. Although not strictly defined in function, they are known to interact and/or bind with multiple members of a signaling pathway, tethering them into complexes. |
MAP3K7, CACNA1G, KRT18, KRT8, VIM, DSP, GJA1, ATP2B4, MAPK3, NOS3, MAP2K2, CAV2, DLG4, MDM2, PDE4D, KCNH2, CASP8, NLGN4X, NLGN1, PANX1, TREM1, CRIPT |
GO:0097153 | MF | cysteine-type endopeptidase activity involved in apoptotic process | Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile, and contributing to the apoptotic process. |
CASP9, CASP6, CASP8, PYCARD |
GO:0097157 | MF | pre-mRNA intronic binding | Interacting selectively and non-covalently with an intronic sequence of a pre-messenger RNA (pre-mRNA). |
HNRNPL, HNRNPA2B1, SOX9, EP300, RNPC3, RBM4 |
GO:0097158 | MF | pre-mRNA intronic pyrimidine-rich binding | Interacting selectively and non-covalently with a pyrimidine-rich (CU-rich) intronic sequence of a pre-messenger RNA (pre-mRNA). |
RBM4 |
GO:0097159 | MF | organic cyclic compound binding | Interacting selectively and non-covalently with an organic cyclic compound, any molecular entity that contains carbon arranged in a cyclic molecular structure. |
MTNR1A |
GO:0097161 | MF | DH domain binding | Interacting selectively and non-covalently with a DH (Dbl homology) domain of a protein. The DH domain contains three structurally conserved regions separated by more variable regions. It is composed of 11 alpha helices that are folded into a flattened, elongated alpha-helix bundle in which two of the three conserved regions, conserved region 1 (CR1) and conserved region 3 (CR3), are exposed near the centre of one surface. CR1 and CR3, together with a part of alpha-6 and the DH/PH (pleckstrin homology) junction site, constitute the Rho GTPase interacting pocket. |
EPHA4 |
GO:0097177 | MF | mitochondrial ribosome binding | Interacting selectively and non-covalently with any part of a mitochondrial ribosome, a ribosome found in the mitochondrion of a eukaryotic cell. |
C1QBP |
GO:0097199 | MF | cysteine-type endopeptidase activity involved in apoptotic signaling pathway | Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile, and contributing to the apoptotic signaling pathway. |
CASP8 |
GO:0097200 | MF | cysteine-type endopeptidase activity involved in execution phase of apoptosis | Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile, and contributing to the execution phase of apoptosis. |
CFLAR |
GO:0097260 | MF | eoxin A4 synthase activity | Catalysis of the reaction: leukotriene A4 = eoxin A4. |
ALOX15 |
GO:0097322 | MF | 7SK snRNA binding | Interacting selectively and non-covalently with a 7SK small nuclear RNA (7SK snRNA). |
CCNT1, CCNT2, HEXIM1 |
GO:0097363 | MF | protein O-GlcNAc transferase activity | Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + [protein]-L-serine = UDP + [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine, or UDP-N-acetyl-D-glucosamine + [protein]-L-threonine = UDP + [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine. |
OGT, POMGNT2 |
GO:0097371 | MF | MDM2/MDM4 family protein binding | Interacting selectively and non-covalently with any isoform of the MDM2/MDM4 protein family, comprising negative regulators of p53. |
PSME3, PPARA, RFWD3 |
GO:0097383 | MF | dIDP diphosphatase activity | Catalysis of the reaction: dIDP + H2O = dIMP + phosphate. |
NUDT16 |
GO:0097493 | MF | structural molecule activity conferring elasticity | The action of a molecule that contributes to the structural integrity of a complex or assembly within or outside a cell, providing elasticity and recoiling. |
AHNAK, TTN |
GO:0097573 | MF | glutathione oxidoreductase activity | Catalysis of the reaction: protein-S-S-glutathione + glutathione-SH = protein-SH + glutathione-S-S-glutathione. |
GLRX |
GO:0097602 | MF | cullin family protein binding | Interacting selectively and non-covalently with any member of the cullin family, hydrophobic proteins that act as scaffolds for ubiquitin ligases (E3). |
PARK2, RBX1, SKP1, DCUN1D4, DCUN1D1 |
GO:0097603 | MF | temperature-gated ion channel activity | Enables the transmembrane transfer of an ion by a channel that opens in response to a temperature stimulus (e.g. exposure to a temperature range different than the optimal temperature for that organism). |
TRPV1 |
GO:0097626 | MF | low-affinity L-arginine transmembrane transporter activity | Catalysis of the transfer of L-arginine from one side of a membrane to the other. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations. |
SLC7A2 |
GO:0097627 | MF | high-affinity L-ornithine transmembrane transporter activity | Catalysis of the transfer of L-ornithine from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations. |
SLC7A2 |
GO:0097655 | MF | serpin family protein binding | Interacting selectively and non-covalently with any member of the serpin protein family (serine protease inhibitors or classified inhibitor family I4). Serpins are a broadly distributed family of protease inhibitors that use a conformational change to inhibit target enzymes. They are central in controlling many important proteolytic cascades. The majority of serpins inhibit serine proteases, but serpins that inhibit caspases and papain-like cysteine proteases have also been identified. Rarely, serpins perform a non-inhibitory function; for example, several human serpins function as hormone transporters and certain serpins function as molecular chaperones or tumor suppressors. |
CTSL |
GO:0097677 | MF | STAT family protein binding | Interacting selectively and non-covalently with any member of the signal transducers and activators of transcription (STAT) protein family. STATs are, as the name indicates, both signal transducers and transcription factors. STATs are activated by cytokines and some growth factors and thus control important biological processes including cell growth, cell differentiation, apoptosis and immune responses. |
HSF1 |
GO:0097689 | MF | iron channel activity | Enables the facilitated diffusion of an iron ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. |
SLC40A1 |
GO:0098505 | MF | G-rich strand telomeric DNA binding | Interacting selectively and non-covalently with G-rich, single-stranded, telomere-associated DNA. |
HNRNPA1, TERF1, NABP2, POT1 |
GO:0098519 | MF | nucleotide phosphatase activity, acting on free nucleotides | Catalysis of the reaction: nucleotide + H2O = nucleotide + phosphate. |
DUSP11, NUDT16 |
GO:0098531 | MF | transcription factor activity, direct ligand regulated sequence-specific DNA binding | A DNA binding transcription factor activity that is directly regulated by binding of a ligand to the protein with this activity. Examples include the lac and trp repressors in E.coli and many steroid hormone receptors. |
RORA |
GO:0098599 | MF | palmitoyl hydrolase activity | Catalysis of a hydrolase reaction that removes a palmitoyl moiety from some substrate. |
PPT2 |
GO:0098619 | MF | selenocysteine-tRNA ligase activity | Catalysis of the reaction: tRNASec + L-Ser + ATP ---> Ser-tRNASec + AMP + Diphosphate. |
SARS |
GO:0098621 | MF | phosphoseryl-selenocysteinyl-tRNA selenium transferase activity | Catalysis of the reaction: O-Phosphoseryl-tRNA(Sec) + Selenophosphoric acid + H2O => L-Selenocysteinyl-tRNA(Sec) + 2 phosphoric acid. |
SEPSECS |
GO:0098625 | MF | methylselenol reductase activity | Catalysis of the reaction: NADPH + H+ + CH3SeOH => NADP+ + CH3SeH + H2O |
TXNRD1 |
GO:0098626 | MF | methylseleninic acid reductase activity | Catalysis of the reaction: NADPH + H+ + CH3SeO2H => NADP+ + CH3SeOH + H2O. |
TXNRD1 |
GO:0098639 | MF | collagen binding involved in cell-matrix adhesion | Any collagen binding that occurs as part of cell-matrix adhesion. |
ITGA10, ITGB1, ITGA2, ITGA11 |
GO:0098641 | MF | cadherin binding involved in cell-cell adhesion | Any cadherin binding that occurs as part of the process of cell-cell adhesion. |
ESYT2, PDLIM1, CLIC1, SDCBP, NOP56, DDX3X, CCS, PPL, EXOC3, CTNND1, FLNB, IDH1, RSL1D1, CCNB2, VAPB, LYPLA2, LDHA, EGFR, ALDOA, ANXA1, ITGB1, KRT18, ENO1, ANXA2, PFN1, SLC3A2, HSP90AB1, HSPA1A, HSPA1B, HSPA5, EEF2, PKM, JUP, EZR, RPS2, EPCAM, CAST, FLNA, PCMT1, PAICS, ITGA6, DNAJB1, S100P, CTNNA2, EEF1D, PRDX6, YWHAB, SFN, S100A11, CTNNA1, CTNNB1, RDX, MYH9, BSG, TAGLN2, CAPG, EIF2S3, TMPO, TMPO, EPS15, RANBP1, RANGAP1, CRKL, IQGAP1, CAPZB, RPL29, CSNK1D, RPL34, FASN, NUMB, MRE11A, EMD, RPL14, CCT8, CAPZA1, ARFIP1, IST1, RARS, EIF5, RPL15, YWHAE, RPL7A, RPL23A, RAB1A, RPS26, YWHAZ, RACK1, HIST1H3D, RPL24, HDLBP, SPTBN1, CALD1, PRDX1, TJP1, GOLGA2, AHNAK, TWF1, DLG1, PAK2, PICALM, SNX1, CKAP5, CTTN, TRIM25, SEPT2, STK38, PCBP1, CNN3, MAPRE1, RAB11B, SEPT7, PKN2, DBN1, FSCN1, LRRFIP1, COBLL1, FNBP1L, ARHGEF16, TWF2, LARP1, MPRIP, GIGYF2, BZW1, DHX29, PHLDB2, KTN1, ERC1, ABI1, ARHGAP18, SERBP1, GPRC5A, STXBP6, KIAA1524, ZC3H15, PPP1R13L, ATXN2L, H1FX, NDRG1, GCN1, EFHD2, PDLIM5, SCYL1, FMNL2, FAM129B, PKP2, CORO1B, EHD4, CHMP4B, EPB41L1, RTN4, ANLN, DIAPH3, PARVA, ARGLU1, VAPA, TJP2, TES, LIMA1, BAIAP2L1, PUF60, ASAP1, MKL2, MYO6, MACF1, RUVBL1, SH3GLB1, PKP3, TLN1, PPME1, SNX9, SNX5, F11R, STK24, BZW2, WASF2 |
GO:0098770 | MF | FBXO family protein binding | Interacting selectively and non-covalently with any member of the FBXO protein family. Members of this family have an F-box protein motif of approximately 50 amino acids that functions as a site of protein-protein interaction. |
CDK6 |
GO:0098772 | MF | molecular function regulator | A molecular function that modulates the activity of a gene product or complex. Examples include enzyme regulators and channel regulators. |
SEC14L1 |
GO:0098821 | MF | BMP receptor activity | Combining with a member of the bone morphogenetic protein (BMP) family, and transmitting a signal across the plasma membrane to initiate a change in cell activity. |
ACVR2A, BMPR1A, BMPR2 |
GO:0098847 | MF | sequence-specific single stranded DNA binding | Interacting selectively and non-covalently with single-stranded DNA of a specific nucleotide composition. |
HSF1, PCBP1 |
GO:0101020 | MF | estrogen 16-alpha-hydroxylase activity | Catalysis of the reaction: estrogen + donor-H2 + O2 = 16-alpha-hydroxyestrogen + H2O. |
CYP1A1, CYP3A4, CYP3A5, CYP3A7 |
GO:0102007 | MF | acyl-L-homoserine-lactone lactonohydrolase activity | Catalysis of the reaction: H2O + an N-acyl-L-homoserine lactone <=> H+ + an N-acyl-L-homoserine. |
PON1 |
GO:0102132 | MF | 3-oxo-pimeloyl-[acp] methyl ester reductase activity | Catalysis of the reaction: NADP + a 3R-hydroxypimeloyl-[acp] methyl ester <=> NADPH + H+ + a 3-oxo-pimeloyl-[acp] methyl ester. |
FASN |