| GO ID | Ontology | GO Term | Term Definition |
Proteins |
GO:0031996 | MF | thioesterase binding | Interacting selectively and non-covalently with any thioesterase enzyme. |
CDC42, CALM2, RAC1, TRAF1, HAUS7 |
GO:0031997 | MF | N-terminal myristoylation domain binding | Interacting selectively and non-covalently with the N-terminus of a protein that has the potential to be, or has been, modified by N-terminal myristoylation. Binding affinity is typically altered by myristoylation; for example, N-terminal myristoylation of HIV Nef increases its affinity for calmodulin. |
CALM2 |
GO:0032027 | MF | myosin light chain binding | Interacting selectively and non-covalently with a light chain of a myosin complex. |
CXCR4, MYO19 |
GO:0032036 | MF | myosin heavy chain binding | Interacting selectively and non-covalently with a heavy chain of a myosin complex. |
MYL9, CORO1A, PDLIM2 |
GO:0032038 | MF | myosin II heavy chain binding | Interacting selectively and non-covalently with a heavy chain of a myosin II complex. |
MYL4 |
GO:0032041 | MF | NAD-dependent histone deacetylase activity (H3-K14 specific) | Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 14) + H2O = histone H3 L-lysine (position 14) + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from lysine at position 14 of the histone H3 protein. |
HDAC3, HDAC4, HDAC1, HDAC7, HDAC2, HDAC8, HDAC6, HDAC9, HDAC5 |
GO:0032050 | MF | clathrin heavy chain binding | Interacting selectively and non-covalently with a clathrin heavy chain. |
LDLR, CLTA, PICALM, CEMIP |
GO:0032051 | MF | clathrin light chain binding | Interacting selectively and non-covalently with a clathrin light chain. |
NSG1 |
GO:0032052 | MF | bile acid binding | Interacting selectively and non-covalently with bile acids, any of a group of steroid carboxylic acids occurring in bile. |
FABP6, AKR1C2, AKR1C1, NR1H4 |
GO:0032090 | MF | Pyrin domain binding | Interacting selectively and non-covalently with a Pyrin (PAAD/DAPIN) domain, a protein-protein interaction domain that has the same fold as the Death domain. |
PYCARD |
GO:0032093 | MF | SAM domain binding | Interacting selectively and non-covalently with a SAM (Sterile Alpha Motif) domain, which is a 70-amino acid protein sequence that participates in protein-protein, protein-lipid, and protein-RNA interactions and is conserved from lower to higher eukaryotes. |
L3MBTL1 |
GO:0032137 | MF | guanine/thymine mispair binding | Interacting selectively and non-covalently with double-stranded DNA containing a G/T mispair. |
MLH1, MSH2, MSH6 |
GO:0032139 | MF | dinucleotide insertion or deletion binding | Interacting selectively and non-covalently with double-stranded DNA containing a dinucleotide insertion or deletion. |
PCNA, MSH3, MSH2 |
GO:0032142 | MF | single guanine insertion binding | Interacting selectively and non-covalently with double-stranded DNA containing a single guanine insertion or a deletion that results in an unpaired guanine. |
MSH3, MSH2, MSH6 |
GO:0032143 | MF | single thymine insertion binding | Interacting selectively and non-covalently with double-stranded DNA containing a single thymine insertion or a deletion that results in an unpaired thymine. |
MSH2, MSH6 |
GO:0032145 | MF | succinate-semialdehyde dehydrogenase binding | Interacting selectively and non-covalently with succinate-semialdehyde dehydrogenase. |
ABAT |
GO:0032181 | MF | dinucleotide repeat insertion binding | Interacting selectively and non-covalently with double-stranded DNA containing a dinucleotide repeat insertion or a deletion resulting in unpaired dinucleotide repeats. |
MSH3, MSH2 |
GO:0032182 | MF | ubiquitin-like protein binding | Interacting selectively and non-covalently with a small conjugating protein such as ubiquitin or a ubiquitin-like protein. |
DCUN1D4, DCUN1D1 |
GO:0032183 | MF | SUMO binding | Interacting selectively and non-covalently with the small ubiquitin-like protein SUMO. |
TDG, TOLLIP, USP25 |
GO:0032184 | MF | SUMO polymer binding | Interacting selectively and non-covalently with a polymer of the small ubiquitin-like protein SUMO. |
SOBP, RNF111, SIMC1 |
GO:0032190 | MF | acrosin binding | Interacting selectively and non-covalently with acrosin, a protein that is found in the acrosomes of sperm and possesses protease and carbohydrate binding activities. |
SERPINA5, ZP3 |
GO:0032217 | MF | riboflavin transporter activity | Enables the directed movement of riboflavin into, out of or within a cell, or between cells. Riboflavin (vitamin B2) is a water-soluble B-complex vitamin, converted in the cell to FMN and FAD, cofactors required for the function of flavoproteins. |
SLC52A3 |
GO:0032266 | MF | phosphatidylinositol-3-phosphate binding | Interacting selectively and non-covalently with phosphatidylinositol-3-phosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3' position. |
SH3PXD2B, SNX3, NCF4, WIPI1, TECPR1, DENND1A, PARD3, SNX19, SNX21, ZFYVE19, PLEKHA5, SNX24, WDR45, WIPI2 |
GO:0032357 | MF | oxidized purine DNA binding | Interacting selectively and non-covalently with oxidized purine residues in DNA. |
MSH2, MSH6 |
GO:0032393 | MF | MHC class I receptor activity | Combining with an MHC class I protein complex to initiate a change in cellular activity. Class I here refers to classical class I molecules. |
LILRB1, MR1 |
GO:0032395 | MF | MHC class II receptor activity | Combining with an MHC class II protein complex and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. |
HLA-DRA, HLA-DQA2, HLA-DQA1, HLA-DQB1, HLA-DOB, HLA-DPA1, HLA-DRB3, KRT17 |
GO:0032403 | MF | protein complex binding | Interacting selectively and non-covalently with any protein complex (a complex of two or more proteins that may include other nonprotein molecules). |
APBB1, NDUFA4, KRIT1, ITGB1BP1, FYB, CFLAR, ULK1, TULP3, CRTAP, MYC, NRAS, KRAS, NR3C1, ITGB2, ITGB1, KRT8, C8G, TUBB, KRT19, RRAS, PTPRF, HSPD1, THRA, CDK4, HCLS1, EPCAM, ITGA2, ATF1, UQCRC2, FBLN1, PPIB, NFYB, UQCRC1, YWHAB, FBN1, PPP1CC, SREBF1, CDKN1A, CAPG, MTHFR, NSF, CDKN1B, IQGAP1, UQCRFS1, TMED10, RANBP2, BCAP31, KIF11, IST1, EPHB1, ATP6V0D1, PPP1CA, RAP1A, GNB1, RBX1, GNB2, AP2B1, IGBP1, DLG4, SLC25A3, SPTBN1, RELA, KHDRBS1, PPARA, TWF1, STRN3, FADD, PDCL, MAPK8IP2, RIPK1, CUL2, PTCH1, DAG1, GIT2, COG2, CASP8, TCEB1, NR0B2, TRADD, TSN, TAB1, NCOA1, LRRC16A, CYFIP1, SLF2, ABI1, FLCN, KAT6B, KAT2B, UFD1L, TXN2, SLF1, TAPBPL, NDEL1, STRN4, RAD18, ABI2, PLK2, CRIPT, GIT1, WASF2 |
GO:0032405 | MF | MutLalpha complex binding | Interacting selectively and non-covalently with the mismatch repair complex MutLalpha. |
PCNA, MSH2, MSH6 |
GO:0032407 | MF | MutSalpha complex binding | Interacting selectively and non-covalently with the mismatch repair complex MutSalpha. |
MLH1, MUTYH |
GO:0032422 | MF | purine-rich negative regulatory element binding | Interacting selectively and non-covalently with a 30-bp purine-rich negative regulatory element; the best characterized such element is found in the first intronic region of the rat cardiac alpha-myosin heavy chain gene, and contains two palindromic high-affinity Ets-binding sites (CTTCCCTGGAAG). The presence of this element restricts expression of the gene containing it to cardiac myocytes. |
ELK3, PURA |
GO:0032427 | MF | GBD domain binding | Interacting selectively and non-covalently with the GTPase protein binding domain (GDB) domain of a protein. The GBD is a short motif, including a minimum region of 16 amino acids, identified in proteins that bind to small GTPases such as Cdc42 and Rac. |
RHOQ |
GO:0032428 | MF | beta-N-acetylgalactosaminidase activity | Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-galactosamine residues in N-acetyl-beta-D-galactosaminides. |
GM2A |
GO:0032440 | MF | 2-alkenal reductase [NAD(P)] activity | Catalysis of the reaction: n-alkanal + NAD(P)+ = alk-2-enal + NAD(P)H + H+. |
PTGR1 |
GO:0032448 | MF | DNA hairpin binding | Interacting selectively and non-covalently with DNA containing a hairpin. A hairpin structure forms when a DNA strand folds back on itself and intrachain base pairing occurs between inverted repeat sequences. |
NR0B1 |
GO:0032450 | MF | maltose alpha-glucosidase activity | Catalysis of the reaction: alpha-maltose + H2O = 2 alpha-D-glucose. |
MGAM, GAA |
GO:0032451 | MF | demethylase activity | Catalysis of the removal of a methyl group from a substrate. |
KDM1A, CYP1A1 |
GO:0032452 | MF | histone demethylase activity | Catalysis of the removal of a methyl group from a histone. |
UTY, KDM6A, KDM1A, KDM4B, KDM5A, ARID5B, JMJD6, KDM7A, KDM5B, KDM2A |
GO:0032453 | MF | histone demethylase activity (H3-K4 specific) | Catalysis of the removal of a methyl group from lysine at position 4 of the histone H3 protein. |
KDM1A, KDM5B |
GO:0032454 | MF | histone demethylase activity (H3-K9 specific) | Catalysis of the reaction: histone H3 N6-methyl-L-lysine (position 9) + alpha-ketoglutarate + O2 = succinate + CO2 + formaldehyde + lysine. This reaction is the removal of a methyl group from lysine at position 9 of the histone H3 protein. |
KDM1A, JMJD1C, KDM7A |
GO:0032542 | MF | sulfiredoxin activity | Catalysis of the reaction: peroxiredoxin-(S-hydroxy-S-oxocysteine) + ATP + 2 R-SH = peroxiredoxin-(S-hydroxycysteine) + ADP + phosphate + R-S-S-R. |
SESN2 |
GO:0032549 | MF | ribonucleoside binding | Interacting selectively and non-covalently with a ribonucleoside, a compound consisting of a purine or pyrimidine nitrogenous base linked to ribose. |
POLR2B, POLR3B |
GO:0032556 | MF | pyrimidine deoxyribonucleotide binding | Interacting selectively and non-covalently with a pyrimidine deoxyribonucleotide, any compound consisting of a pyrimidine deoxyribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety. |
DCTPP1 |
GO:0032557 | MF | pyrimidine ribonucleotide binding | Interacting selectively and non-covalently with a pyrimidine ribonucleotide, any compound consisting of a pyrimidine ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety. |
UGP2 |
GO:0032564 | MF | dATP binding | Interacting selectively and non-covalently with dATP, deoxyadenosine triphosphate. |
HSP90AA1, HSP90AB1 |
GO:0032567 | MF | dGTP binding | Interacting selectively and non-covalently with dGTP, deoxyguanosine triphosphate. |
SAMHD1 |
GO:0032767 | MF | copper-dependent protein binding | Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules), in the presence of copper. |
ATOX1, FKBP4 |
GO:0032791 | MF | lead ion binding | Interacting selectively and non-covalently with lead (Pb) ions. |
ALAD |
GO:0032794 | MF | GTPase activating protein binding | Interacting selectively and non-covalently with a GTPase activating protein. |
TUBB, GNAI3, AKT1, PLCD1, GNAI1 |
GO:0032795 | MF | heterotrimeric G-protein binding | Interacting selectively and non-covalently with a heterotrimeric G-protein. |
ADORA1 |
GO:0032810 | MF | sterol response element binding | Interacting selectively and non-covalently with the sterol response element (SRE), a nonpalindromic sequence found in the promoters of genes involved in lipid metabolism. |
SREBF1, NR1H3 |
GO:0032813 | MF | tumor necrosis factor receptor superfamily binding | Interacting selectively and non-covalently with any member of the tumor necrosis factor receptor superfamily. |
TNFSF11, TNFSF4, FADD |
GO:0032947 | MF | protein complex scaffold | Functions to provide a physical support for the assembly of a multiprotein complex. |
CNOT1, AXIN1, CAPN3, CAV2, EIF3B, RACK1, CAV1, AKAP13, DLG1, AKAP6, SEPT2, ITSN1, WWC2, LAMTOR1, WWC1, RB1CC1, SMARCD1, MAGI1, PKP2, LAMTOR3, WWC3, LAMTOR2 |
GO:0033130 | MF | acetylcholine receptor binding | Interacting selectively and non-covalently with an acetylcholine receptor. |
JAK2, DLG4, LYPD1, NRXN1 |
GO:0033142 | MF | progesterone receptor binding | Interacting selectively and non-covalently with a progesterone receptor. |
NCOA1 |
GO:0033149 | MF | FFAT motif binding | Interacting selectively and non-covalently with the FFAT motif, a short motif containing diphenylalanine in an acidic tract that targets proteins to the cytosolic surface of the ER and to the nuclear membrane by binding directly to members of the VAP (VAMP-associated protein) protein family. |
VAPB, VAPA |
GO:0033188 | MF | sphingomyelin synthase activity | Catalysis of the reaction: 1,2-diacyl-sn-glycero-3-phosphocholine + ceramide = 1,2-diacyl-sn-glycerol + sphingomyelin. |
SGMS1, SGMS2 |
GO:0033192 | MF | calmodulin-dependent protein phosphatase activity | Catalysis of the reaction: protein serine/threonine phosphate + H2O = protein serine/threonine + phosphate, dependent on the presence of calcium-bound calmodulin. |
PPM1F, PPP3CA |
GO:0033204 | MF | ribonuclease P RNA binding | Interacting selectively and non-covalently with the RNA subunit of ribonuclease P. |
POP4 |
GO:0033218 | MF | amide binding | Interacting selectively and non-covalently with an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group. |
SRD5A1, SRD5A2, PHB2 |
GO:0033265 | MF | choline binding | Interacting selectively and non-covalently with choline, the amine 2-hydroxy-N,N,N-trimethylethanaminium. |
CRP, CHKA |
GO:0033300 | MF | dehydroascorbic acid transporter activity | Enables the directed movement of dehydroascorbate, 5-(1,2-dihydroxyethyl)furan-2,3,4(5H)-trione, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
SLC2A1, SLC2A3 |
GO:0033549 | MF | MAP kinase phosphatase activity | Catalysis of the reaction: a phosphorylated MAP kinase + H2O = a MAP kinase + phosphate. |
DUSP3, DUSP10 |
GO:0033558 | MF | protein deacetylase activity | Catalysis of the hydrolysis of an acetyl group or groups from a protein substrate. |
HDAC3, HDAC4, HDAC1, SIRT2, HDAC2, HDAC9, HDAC5 |
GO:0033560 | MF | folate reductase activity | Catalysis of the reaction: 7,8-dihydrofolate + NADP+ = folate + NADPH + H+. |
DHFR |
GO:0033570 | MF | transferrin transmembrane transporter activity | Enables the transfer of transferrin from one side of a membrane to the other. |
TFRC, SLC11A2 |
GO:0033592 | MF | RNA strand annealing activity | Facilitates the base-pairing of complementary single-stranded RNA. |
EIF4B, FXR1, FMR1 |
GO:0033612 | MF | receptor serine/threonine kinase binding | Interacting selectively and non-covalently with a receptor that possesses protein serine/threonine kinase activity. |
BMP10 |
GO:0033613 | MF | activating transcription factor binding | Interacting selectively and non-covalently with an activating transcription factor, any protein whose activity is required to initiate or upregulate transcription. |
PPARG, GATA4, HDAC4, MEF2A, RELA, MEF2C, EP300, HDAC1, MEF2D, SMAD2, HDAC7, ATOH8 |
GO:0033676 | MF | double-stranded DNA-dependent ATPase activity | Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction requires the presence of double-stranded DNA, and it drives another reaction. |
ANXA1 |
GO:0033682 | MF | ATP-dependent 5'-3' DNA/RNA helicase activity | Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of a DNA/RNA duplex in the direction 5' to 3'. |
PIF1 |
GO:0033691 | MF | sialic acid binding | Interacting selectively and non-covalently with sialic acid, any of a variety of N- or O- substituted derivatives of neuraminic acid, a nine carbon monosaccharide. Sialic acids often occur in polysaccharides, glycoproteins, and glycolipids in animals and bacteria. |
SELE, ADIPOQ, ST8SIA4 |
GO:0033737 | MF | 1-pyrroline dehydrogenase activity | Catalysis of the reaction: 1-pyrroline + NAD+ + 2 H2O = 4-aminobutanoate + NADH + 2 H+. |
ALDH9A1 |
GO:0033743 | MF | peptide-methionine (R)-S-oxide reductase activity | Catalysis of the reaction: peptide-L-methionine + H(2)O + thioredoxin disulfide = peptide-L-methionine (R)-S-oxide + thioredoxin. Can act on oxidized methionine in peptide linkage with specificity for the R enantiomer. Thioredoxin disulfide is the oxidized form of thioredoxin. |
MSRB3, TXN2 |
GO:0033746 | MF | histone demethylase activity (H3-R2 specific) | Catalysis of the removal of a methyl group from arginine at position 2 of the histone H3 protein. |
JMJD6 |
GO:0033749 | MF | histone demethylase activity (H4-R3 specific) | Catalysis of the removal of a methyl group from arginine at position 3 of the histone H4 protein. |
JMJD6 |
GO:0033778 | MF | 7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase activity | Catalysis of the reaction: 7alpha-hydroxycholest-4-en-3-one + H(+) + NADPH + O(2) = 7alpha,12alpha-dihydroxycholest-4-en-3-one + H(2)O + NADP(+). |
CYP8B1 |
GO:0033780 | MF | taurochenodeoxycholate 6alpha-hydroxylase activity | Catalysis of the reactions: taurochenodeoxycholate + NADPH + H+ + O2 = taurohyocholate + NADP+ + H2O, and lithocholate + NADPH + H+ + O2 = hyodeoxycholate + NADP+ + H2O. |
CYP3A4 |
GO:0033791 | MF | 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity | Catalysis of the reaction: (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA + H2O + acceptor = (24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestan-26-oyl-CoA + reduced acceptor. |
ACOX2 |
GO:0033814 | MF | propanoyl-CoA C-acyltransferase activity | Catalysis of the reaction: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA + propanoyl-CoA = CoA + 3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestanoyl-CoA. |
SCP2 |
GO:0033857 | MF | diphosphoinositol-pentakisphosphate kinase activity | Catalysis of the reaction: ATP + 1D-myo-inositol 5-diphosphate pentakisphosphate = ADP + 1D-myo-inositol bisdiphosphate tetrakisphosphate. |
PPIP5K1 |
GO:0033858 | MF | N-acetylgalactosamine kinase activity | Catalysis of the reaction: ATP + N-acetyl-D-galactosamine = ADP + N-acetyl-alpha-D-galactosamine 1-phosphate. |
GALK2 |
GO:0033862 | MF | UMP kinase activity | Catalysis of the reaction: ATP + UMP = ADP + UDP. |
CMPK2 |
GO:0033867 | MF | Fas-activated serine/threonine kinase activity | Catalysis of the reaction: ATP + Fas-activated serine/threonine protein = ADP + Fas-activated serine/threonine phosphoprotein. |
FASTK |
GO:0033872 | MF | [heparan sulfate]-glucosamine 3-sulfotransferase 3 activity | Catalysis of the reaction: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate. |
HS3ST3B1 |
GO:0033878 | MF | hormone-sensitive lipase activity | Catalysis of the reactions: diacylglycerol + H2O = monoacylglycerol + a carboxylate; triacylglycerol + H2O = diacylglycerol + a carboxylate; and monoacylglycerol + H2O = glycerol + a carboxylate. |
LIPE |
GO:0033882 | MF | choloyl-CoA hydrolase activity | Catalysis of the reaction: choloyl-CoA + H2O = cholate + CoA. |
ACOT8 |
GO:0033897 | MF | ribonuclease T2 activity | Catalysis of the two-stage endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides with 2',3'-cyclic phosphate intermediates. |
RNASET2 |
GO:0033906 | MF | hyaluronoglucuronidase activity | Catalysis of the random hydrolysis of 1,3-linkages between beta-D-glucuronate and N-acetyl-D-glucosamine residues in hyaluronate. |
HYAL2 |
GO:0033919 | MF | glucan 1,3-alpha-glucosidase activity | Catalysis of the hydrolysis of terminal (1->3)-alpha-D-glucosidic links in 1,3-alpha-D-glucans. |
GANAB |
GO:0033925 | MF | mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity | Catalysis of the endohydrolysis of the N,N'-diacetylchitobiosyl unit in high-mannose glycopeptides and glycoproteins containing the -[Man(GlcNAc)2]Asn-structure. One N-acetyl-D-glucosamine residue remains attached to the protein; the rest of the oligosaccharide is released intact. |
ENGASE |
GO:0033961 | MF | cis-stilbene-oxide hydrolase activity | Catalysis of the reaction: cis-stilbene oxide + H2O = (+)-(1R,2R)-1,2-diphenylethane-1,2-diol. |
EPHX1 |
GO:0033981 | MF | D-dopachrome decarboxylase activity | Catalysis of the reaction: D-dopachrome + H(+) = 5,6-dihydroxyindole + CO(2). |
DDT |
GO:0033989 | MF | 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity | Catalysis of the reaction: (24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA = (24E)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA + H2O. |
HSD17B4 |
GO:0034012 | MF | FAD-AMP lyase (cyclizing) activity | Catalysis of the reaction: FAD = AMP + riboflavin cyclic-4',5'-phosphate. |
TKFC |
GO:0034038 | MF | deoxyhypusine synthase activity | Catalysis of the reaction: [eIF5A-precursor]-lysine + spermidine = [eIF5A-precursor]-deoxyhypusine + propane-1,3-diamine. Four sub-reactions have been identified,in which the intermediates remain tightly associated with the enzyme: spermidine + NAD+ = dehydrospermidine + NADH; dehydrospermidine + [enzyme]-lysine = N-(4-aminobutylidene)-[enzyme]-lysine + propane-1,3-diamine; N-(4-aminobutylidene)-[enzyme]-lysine + [eIF5A-precursor]-lysine = N-(4-aminobutylidene)-[eIF5A-precursor]-lysine + [enzyme]-lysine; N-(4-aminobutylidene)-[eIF5A-precursor]-lysine + NADH + H+ = [eIF5A-precursor]-deoxyhypusine + NAD+. |
DHPS |
GO:0034046 | MF | poly(G) binding | Interacting selectively and non-covalently with a sequence of guanine residues in an RNA molecule. |
ATXN1, HNRNPU, FMR1, PNPT1 |
GO:0034056 | MF | estrogen response element binding | Interacting selectively and non-covalently with the estrogen response element (ERE), a conserved sequence found in the promoters of genes whose expression is regulated in response to estrogen. |
TOX3, ESR1, ESR2 |
GO:0034057 | MF | RNA strand-exchange activity | Facilitates the displacement of one strand of an RNA-RNA duplex and its replacement with a different strand of higher complementarity. |
EIF4B |
GO:0034062 | MF | RNA polymerase activity | Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); the synthesis of RNA from ribonucleotide triphosphates in the presence of a nucleic acid template. |
TRNT1 |
GO:0034185 | MF | apolipoprotein binding | Interacting selectively and non-covalently with an apolipoprotein, the protein component of a lipoprotein complex. |
LRP6, ABCA1, PLG, LPL, MAPT, CANX, VLDLR, PCSK9, SCARB1 |