| GO ID | Ontology | GO Term | Term Definition |
Proteins |
GO:0015616 | MF | DNA translocase activity | Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive movement along a single- or double-stranded DNA molecule. |
FSBP, ATRX, FBXO18, RAD54B |
GO:0015631 | MF | tubulin binding | Interacting selectively and non-covalently with monomeric or multimeric forms of tubulin, including microtubules. |
EML1, PARK2, TPPP, EML2, ALDOA, PRNP, FYN, TPR, STMN1, CLIP1, BRCA1, NCALD, DAG1, KIF14, IFT81, RITA1, AGBL1, CENPJ, STMN3, AGTPBP1, HDGFRP3, RABGAP1 |
GO:0015639 | MF | ferrous iron uptake transmembrane transporter activity | Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Fe2+(out) + energy = Fe2+(in). |
SLC11A2 |
GO:0015643 | MF | toxic substance binding | Interacting selectively and non-covalently with a toxic substance, a poisonous substance that causes damage to biological systems. |
ASS1, ALB, CHRNA7, PHAX, TMEM181 |
GO:0015645 | MF | fatty acid ligase activity | Catalysis of the ligation of a fatty acid to an acceptor, coupled to the hydrolysis of ATP. |
ACSM3 |
GO:0015651 | MF | quaternary ammonium group transmembrane transporter activity | Enables the transfer of quaternary ammonium groups from one side of a membrane to the other. Quaternary ammonium groups are any compound that can be regarded as derived from ammonium hydroxide or an ammonium salt by replacement of all four hydrogen atoms of the NH4+ ion by organic groups. |
SLC22A1, SLC22A3, SLC22A5 |
GO:0015662 | MF | ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism | Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of ions across a membrane. The reaction is characterized by the transient formation of a high-energy aspartyl-phosphoryl-enzyme intermediate. |
ABCC4 |
GO:0015923 | MF | mannosidase activity | Catalysis of the hydrolysis of mannosyl compounds, substances containing a group derived from a cyclic form of mannose or a mannose derivative. |
MAN1A1 |
GO:0016004 | MF | phospholipase activator activity | Increases the activity of a phospholipase, an enzyme that catalyzes of the hydrolysis of a glycerophospholipid. |
CCL3, CCL5, GM2A, CCL8 |
GO:0016005 | MF | phospholipase A2 activator activity | Increases the activity of the enzyme phospholipase A2. |
PLAA |
GO:0016015 | MF | morphogen activity | Acts as a trigger for a pattern specification process when present at a specific concentration within a gradient. |
GREM1, NBL1 |
GO:0016018 | MF | cyclosporin A binding | Interacting selectively and non-covalently with cyclosporin A, a cyclic undecapeptide that contains several N-methylated and unusual amino acids. |
PPIH, PPIF, NKTR, PPIC, PPID, PPIG, PPIE |
GO:0016019 | MF | peptidoglycan receptor activity | Combining with a peptidoglycan and transmitting the signal to initiate a change in cell activity. |
CD14, PGLYRP2 |
GO:0016034 | MF | maleylacetoacetate isomerase activity | Catalysis of the reaction: 4-maleylacetoacetate = 4-fumarylacetoacetate. |
GSTZ1 |
GO:0016150 | MF | translation release factor activity, codon nonspecific | A translation release factor that is not specific to particular codons; binds to guanine nucleotides. |
ICT1, C12orf65 |
GO:0016151 | MF | nickel cation binding | Interacting selectively and non-covalently with nickel (Ni) cations. |
CA3 |
GO:0016154 | MF | pyrimidine-nucleoside phosphorylase activity | Catalysis of the reaction: pyrimidine nucleoside + phosphate = pyrimidine + alpha-D-ribose 1-phosphate. |
TYMP |
GO:0016155 | MF | formyltetrahydrofolate dehydrogenase activity | Catalysis of the reaction: 10-formyltetrahydrofolate + H(2)O + NADP(+) = (6S)-5,6,7,8-tetrahydrofolate + CO(2) + H(+) + NADPH. |
ALDH1L1, ALDH1L2 |
GO:0016160 | MF | amylase activity | Catalysis of the hydrolysis of amylose or an amylose derivative. |
MGAM |
GO:0016174 | MF | NAD(P)H oxidase activity | Catalysis of the reaction: NAD(P)H + H+ + O2 = NAD(P)+ + hydrogen peroxide. |
KMO, AIFM1, NOX4, DUOX2, DUOX1 |
GO:0016175 | MF | superoxide-generating NADPH oxidase activity | Catalysis of the reaction: NAD(P)H + O2 = NAD(P)H + O2-. |
CYBB, NCF2, NOX5, NOX4 |
GO:0016176 | MF | superoxide-generating NADPH oxidase activator activity | Increases the activity of the enzyme superoxide-generating NADPH oxidase. |
SH3PXD2B, PDGFB, NCF4, NOXA1 |
GO:0016206 | MF | catechol O-methyltransferase activity | Catalysis of the reaction: S-adenosyl-L-methionine + a catechol = S-adenosyl-L-homocysteine + a guaiacol. |
COMT |
GO:0016208 | MF | AMP binding | Interacting selectively and non-covalently with AMP, adenosine monophosphate. |
CYB5R3, APRT, FBP1, PRKAG1, PRPS1, ACSS2, ACSS1 |
GO:0016209 | MF | antioxidant activity | Inhibition of the reactions brought about by dioxygen (O2) or peroxides. Usually the antioxidant is effective because it can itself be more easily oxidized than the substance protected. The term is often applied to components that can trap free radicals, thereby breaking the chain reaction that normally leads to extensive biological damage. |
HP, APOE, ALB, S100A9, MT3, PRDX2, AAED1, TP53INP1, VIMP, FAM213A |
GO:0016212 | MF | kynurenine-oxoglutarate transaminase activity | Catalysis of the reaction: L-kynurenine + 2-oxoglutarate = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-glutamate. |
GOT2 |
GO:0016213 | MF | linoleoyl-CoA desaturase activity | Catalysis of the reaction: linoleoyl-CoA + reduced acceptor + O2 = gamma-linolenoyl-CoA + acceptor + 2 H2O. |
FADS2 |
GO:0016229 | MF | steroid dehydrogenase activity | Catalysis of an oxidation-reduction (redox) reaction in which one substrate is a sterol derivative. |
HSD17B11 |
GO:0016230 | MF | sphingomyelin phosphodiesterase activator activity | Increases the activity of the enzyme sphingomyelin phosphodiesterase. |
STX4, NSMAF |
GO:0016231 | MF | beta-N-acetylglucosaminidase activity | Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-glucosamine residues in N-acetyl-beta-D-glucosaminides. |
MGEA5 |
GO:0016247 | MF | channel regulator activity | Modulates the activity of a channel. A channel catalyzes energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel. |
CACNG8 |
GO:0016248 | MF | channel inhibitor activity | Stops, prevents, or reduces the activity of a channel. A channel catalyzes energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel. |
BCL2 |
GO:0016250 | MF | N-sulfoglucosamine sulfohydrolase activity | Catalysis of the reaction: N-sulfo-D-glucosamine + H2O = D-glucosamine + sulfate. |
SGSH |
GO:0016262 | MF | protein N-acetylglucosaminyltransferase activity | Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + protein = UDP + 4-N-(N-acetyl-D-glucosaminyl)-protein. |
OGT |
GO:0016274 | MF | protein-arginine N-methyltransferase activity | Catalysis of the reaction: S-adenosyl-L-methionine + (protein)-arginine = S-adenosyl-L-homocysteine + (protein)-N-methyl-arginine. |
PRMT3, CARM1, PRMT6, PRMT1 |
GO:0016278 | MF | lysine N-methyltransferase activity | Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the epsilon-amino group of a lysine residue. |
SETD9, KMT5A |
GO:0016279 | MF | protein-lysine N-methyltransferase activity | Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the epsilon-amino group of a lysine residue in a protein substrate. |
EZH2, METTL10, ETFBKMT, SETD6, SETD7, N6AMT2, METTL21A, EHMT2, KMT5A |
GO:0016287 | MF | glycerone-phosphate O-acyltransferase activity | Catalysis of the reaction: acyl-CoA + glycerone phosphate = 1-acylglycerone 3-phosphate + CoA. |
GNPAT |
GO:0016289 | MF | CoA hydrolase activity | Catalysis of the reaction: X-CoA + H2O = X + CoA; X may be any group. |
ACOT8, NUDT7 |
GO:0016290 | MF | palmitoyl-CoA hydrolase activity | Catalysis of the reaction: palmitoyl-CoA + H2O = CoA + palmitate. |
ACOT7, ACOT8, GNPAT, PPT1, THEM4, ACOT4 |
GO:0016295 | MF | myristoyl-[acyl-carrier-protein] hydrolase activity | Catalysis of the reaction: myristoyl-[acyl-carrier protein] + H2O = [acyl-carrier protein] + myristate. |
FASN |
GO:0016296 | MF | palmitoyl-[acyl-carrier-protein] hydrolase activity | Catalysis of the reaction: palmitoyl-[acyl-carrier protein] + H2O = [acyl-carrier protein] + palmitate. |
FASN |
GO:0016298 | MF | lipase activity | Catalysis of the hydrolysis of a lipid or phospholipid. |
LYPLA1, AADAC, LIPA |
GO:0016301 | MF | kinase activity | Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule. |
CDC7, PIK3CD, CHEK1, FAM20B, RAF1, CCL3, BCR, PRPS2, PKM, CDK2, MAPK3, MAPK1, WEE1, AKT1, CSK, PIK3CA, PIK3CB, MAPK8, CSNK1A1, PIK3CG, GSK3B, CDK7, IRAK1, PLK1, PRPS1, CDK5, DGKZ, PRKD1, RPS6KA2, RPS6KA1, PKN2, CERKL, SGMS1, PIK3C3, SGMS2, MASTL, NEK1, PKMYT1, PINK1, TPK1, TRRAP |
GO:0016303 | MF | 1-phosphatidylinositol-3-kinase activity | Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol + ATP = a 1-phosphatidyl-1D-myo-inositol 3-phosphate + ADP + 2 H(+). |
PIK3CD, PIK3C2A, FGF18, FGF19, FGF2, FGFR1, FGF7, FGFR2, PIK3R1, FGF9, IRS1, PIK3CA, PIK3CB, PIK3CG, GRB2, PTPN11, GAB1, PIK3C3, FRS2, PIK3R4, KL, IRS2 |
GO:0016308 | MF | 1-phosphatidylinositol-4-phosphate 5-kinase activity | Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4-phosphate + ATP = 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + ADP + 2 H(+). |
PIP5K1B, PIP5K1C, PIP4K2B, PIKFYVE |
GO:0016309 | MF | 1-phosphatidylinositol-5-phosphate 4-kinase activity | Catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 5-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate. |
PIP4K2B |
GO:0016312 | MF | inositol bisphosphate phosphatase activity | Catalysis of the reaction: myo-inositol bisphosphate + H2O = myo-inositol phosphate + phosphate. |
INPP5K |
GO:0016314 | MF | phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity | Catalysis of the reaction: phosphatidylinositol-3,4,5-trisphosphate + H2O = phosphatidylinositol-4,5-bisphosphate + phosphate. |
PTEN, INPP5D |
GO:0016316 | MF | phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity | Catalysis of the reaction: 1-phosphatidyl-myo-inositol 3,4-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol 3-phosphate + phosphate. |
INPP4B, INPP4A |
GO:0016361 | MF | activin receptor activity, type I | Combining with activin-bound type II activin receptor to initiate a change in cell activity; upon binding, acts as a downstream transducer of activin signals. |
ACVR1B, ACVR1 |
GO:0016362 | MF | activin receptor activity, type II | Combining with activin to initiate a change in cell activity; upon ligand binding, binds to and catalyses the phosphorylation of a type I activin receptor. |
ACVR2B, BMPR2 |
GO:0016402 | MF | pristanoyl-CoA oxidase activity | Catalysis of the reaction: pristanoyl-CoA + O2 = trans-2,3-dehydropristanoyl-CoA + hydrogen peroxide. |
ACOX3, ACOX2 |
GO:0016403 | MF | dimethylargininase activity | Catalysis of the reaction: N(G),N(G)-dimethyl-L-arginine + H2O = dimethylamine + L-citrulline. |
DDAH1, DDAH2 |
GO:0016404 | MF | 15-hydroxyprostaglandin dehydrogenase (NAD+) activity | Catalysis of the reaction: (5Z,13E)-(15S)-11-alpha,15-dihydroxy-9-oxoprost-13-enoate + NAD+ = (5Z,13E)-11-alpha-hydroxy-9,15-dioxoprost-13-enoate + NADH + H+. |
ABCC4, HPGD |
GO:0016407 | MF | acetyltransferase activity | Catalysis of the transfer of an acetyl group to an acceptor molecule. |
EP300, KAT6B, CREBBP, KAT6A, KAT2B, NAA15 |
GO:0016409 | MF | palmitoyltransferase activity | Catalysis of the transfer of a palmitoyl (CH3-[CH2]14-CO-) group to an acceptor molecule. |
ZDHHC20, ZDHHC17, ZDHHC14, ZDHHC6, ZDHHC7, ZDHHC2, ZDHHC9 |
GO:0016410 | MF | N-acyltransferase activity | Catalysis of the transfer of an acyl group to a nitrogen atom on the acceptor molecule. |
HRASLS5 |
GO:0016411 | MF | acylglycerol O-acyltransferase activity | Catalysis of the transfer of an acyl group to an oxygen atom on the acylglycerol molecule. |
PNPLA2, PNPLA3 |
GO:0016422 | MF | mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity | Catalysis of the reaction: S-adenosyl-L-methionine + m(7)G(5')pppAm = S-adenosyl-L-homocysteine + m(7)G(5')pppm(6)Am. |
METTL14 |
GO:0016423 | MF | tRNA (guanine) methyltransferase activity | Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing methylguanine. |
THUMPD3 |
GO:0016427 | MF | tRNA (cytosine) methyltransferase activity | Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing methylcytosine. |
METTL2B, METTL2A |
GO:0016428 | MF | tRNA (cytosine-5-)-methyltransferase activity | Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing 5-methylcytosine. |
NSUN2 |
GO:0016430 | MF | tRNA (adenine-N6-)-methyltransferase activity | Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing N6-methyladenine. |
TRMO |
GO:0016462 | MF | pyrophosphatase activity | Catalysis of the hydrolysis of a pyrophosphate bond between two phosphate groups, leaving one phosphate on each of the two fragments. |
ALPL, GMPS, PRUNE2 |
GO:0016491 | MF | oxidoreductase activity | Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced. |
DHRS12, SCD, HSD17B6, KDM1A, FADS1, CREG1, F8, CYP1A1, CYP2E1, CYP3A4, CYP2D6, CYP2C9, CYP3A5, CHM, CHML, GDI1, FDFT1, SNCA, GDI2, SESN3, GSTO1, PIGF, PDIA5, ETFDH, DHRS13, HSDL2, SCD5, ERO1B, ZADH2, OXR1, SUMF1, RDH13, ENOX1, RTN4IP1, KIAA1191, ERO1A, FAR2, DHRS1, HTATIP2, ADI1, C1orf43, GSTO2, SEPN1, OSGIN1, DHRS7 |
GO:0016494 | MF | C-X-C chemokine receptor activity | Combining with a C-X-C chemokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. A C-X-C chemokine has a single amino acid between the first two cysteines of the characteristic four cysteine motif. |
CXCR2, CXCR4 |
GO:0016501 | MF | prostacyclin receptor activity | Combining with prostacyclin (PGI(2)) to initiate a change in cell activity. |
PTGDR |
GO:0016504 | MF | peptidase activator activity | Binds to and increases the activity of a peptidase, any enzyme that catalyzes the hydrolysis peptide bonds. |
CLPX, FN1, APP, FBLN1, MMP14, CAV1, PSME4, PCOLCE, PINK1, PCOLCE2 |
GO:0016505 | MF | peptidase activator activity involved in apoptotic process | Increases the activity of a peptidase that is involved in the apoptotic process. |
EBAG9, MAL, CTSC |
GO:0016508 | MF | long-chain-enoyl-CoA hydratase activity | Catalysis of the reaction: a long-chain (3S)-3-hydroxyacyl-CoA = a long-chain trans-2-enoyl-CoA + H2O. A long-chain acyl-CoA is an acyl-CoA thioester where the acyl chain contains 13 to 22 carbon atoms. |
HSD17B4 |
GO:0016509 | MF | long-chain-3-hydroxyacyl-CoA dehydrogenase activity | Catalysis of the reaction: (S)-3-hydroxyacyl-CoA + NAD(P)+ = 3-oxoacyl-CoA + NAD(P)H + H+, where the acyl group is a long-chain fatty acid residue. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22. |
HADHB, HSD17B12 |
GO:0016517 | MF | interleukin-12 receptor activity | Combining with interleukin-12 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. |
IL12RB1 |
GO:0016520 | MF | growth hormone-releasing hormone receptor activity | Combining with growth hormone-releasing hormone to initiate a change in cell activity. |
GHSR |
GO:0016524 | MF | latrotoxin receptor activity | Combining with alpha-latrotoxin, a potent presynaptic neurotoxin, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. |
ADGRL2 |
GO:0016530 | MF | metallochaperone activity | Assists in the delivery of metal ions to target proteins or compartments. |
ATOX1 |
GO:0016531 | MF | copper chaperone activity | Assists in the delivery of copper ions to target proteins or compartments. |
ATOX1, COX17 |
GO:0016532 | MF | superoxide dismutase copper chaperone activity | A copper chaperone activity that specifically delivers copper to the Cu-Zn superoxide dismutase, to activate superoxide dismutase activity. |
CCS |
GO:0016538 | MF | cyclin-dependent protein serine/threonine kinase regulator activity | Modulates the activity of a cyclin-dependent protein serine/threonine kinase, enzymes of the protein kinase family that are regulated through association with cyclins and other proteins. |
CCNT1, CCNT2, CCNE2, CDK4, CCNL2, CCNL1 |
GO:0016594 | MF | glycine binding | Interacting selectively and non-covalently with glycine, aminoethanoic acid. |
CEP104, GLRB |
GO:0016595 | MF | glutamate binding | Interacting selectively and non-covalently with glutamate, the anion of 2-aminopentanedioic acid. |
CEP104, SLC1A3, GCLC |
GO:0016596 | MF | thienylcyclohexylpiperidine binding | Interacting selectively and non-covalently with thienylcyclohexylpiperidine. |
CEP104 |
GO:0016597 | MF | amino acid binding | Interacting selectively and non-covalently with an amino acid, organic acids containing one or more amino substituents. |
DDAH1, DDAH2, GOT2, ASS1, TH, AGXT, SHMT1, SLC1A3, KARS, TPH2 |
GO:0016603 | MF | glutaminyl-peptide cyclotransferase activity | Catalysis of the reaction: L-glutaminyl-peptide = 5-oxoprolyl-peptide + NH3. |
QPCT |
GO:0016608 | MF | growth hormone-releasing hormone activity | The action characteristic of growth hormone-releasing hormone, any of a family of peptide hormones that act on the anterior pituitary to stimulate the secretion of growth hormone and exert a trophic effect on the gland. |
GHRH, GHRL |
GO:0016614 | MF | oxidoreductase activity, acting on CH-OH group of donors | Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group act as a hydrogen or electron donor and reduces a hydrogen or electron acceptor. |
AGPS, XDH, AOX1, DHCR24 |
GO:0016616 | MF | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP. |
CTBP2, ADHFE1, RDH11 |
GO:0016618 | MF | hydroxypyruvate reductase activity | Catalysis of the reaction: D-glycerate + NADP+ = hydroxypyruvate + NADPH + H+. |
GRHPR |
GO:0016627 | MF | oxidoreductase activity, acting on the CH-CH group of donors | Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor. |
TM7SF2, TECRL |
GO:0016628 | MF | oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor | Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces NAD or NADP. |
DHCR24, BDH2 |
GO:0016641 | MF | oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor | Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces an oxygen molecule. |
LOXL1, LOXL4 |
GO:0016651 | MF | oxidoreductase activity, acting on NAD(P)H | Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor. |
AIFM1, DECR1, MIOX |
GO:0016655 | MF | oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor | Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a quinone or a similar acceptor molecule. |
CBR1, AKR1C3, AKR1C2, AKR1C1, DCXR, DHRS4 |
GO:0016671 | MF | oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor | Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces disulfide. |
TXN, ERO1B, DNAJC10, ERO1A, TXN2 |
GO:0016679 | MF | oxidoreductase activity, acting on diphenols and related substances as donors | Catalysis of an oxidation-reduction (redox) reaction in which a diphenol or related substance acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor. |
CYP1A1 |
GO:0016684 | MF | oxidoreductase activity, acting on peroxide as acceptor | Catalysis of an oxidation-reduction (redox) reaction in which the peroxide group acts as a hydrogen or electron acceptor. |
SESN2 |
GO:0016701 | MF | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen | Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from one donor, and molecular oxygen is incorporated into a donor. |
MIOX |
GO:0016702 | MF | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen | Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from one donor, and two oxygen atoms is incorporated into a donor. |
P4HA2, P4HA1 |
GO:0016705 | MF | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and molecular oxygen is reduced or incorporated into a donor. |
PTGIS, OGFOD3, CYP2R1, CYP4V2, CYP2W1 |
GO:0016706 | MF | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors | Catalysis of the reaction: A + 2-oxoglutarate + O2 = B + succinate + CO2. This is an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from 2-oxoglutarate and one other donor, and one atom of oxygen is incorporated into each donor. |
KDM5A, ALKBH5, KDM7A, MINA, EGLN3, KDM5B |