GO:0005229

MF

intracellular calcium activated chloride channel activity

Enables the transmembrane transfer of chloride by a channel that opens in response to stimulus by a calcium ion or ions. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism.

BEST1, CLCA4, ANO6, ANO2

GO:0005230

MF

extracellular ligand-gated ion channel activity

Enables the transmembrane transfer of an ion by a channel that opens when a specific extracellular ligand has been bound by the channel complex or one of its constituent parts.

GABRA5, CHRNA7, CHRFAM7A, TRPV1

GO:0005231

MF

excitatory extracellular ligand-gated ion channel activity

Enables the transmembrane transfer of an ion by a channel that opens when a specific extracellular excitatory ligand has been bound by the channel complex or one of its constituent parts. Excitatory ligands, such as acetylcholine or glutamate, open cation-selective channels.

GRIA4, TRPV1

GO:0005234

MF

extracellular-glutamate-gated ion channel activity

Enables the transmembrane transfer of an ion by a channel that opens when extracellular glutamate has been bound by the channel complex or one of its constituent parts.

GRIA4, GRIN2A

GO:0005242

MF

inward rectifier potassium channel activity

Enables the transmembrane transfer of a potassium ion by an inwardly-rectifying voltage-gated channel. An inwardly rectifying current-voltage relation is one where at any given driving force the inward flow of K+ ions exceeds the outward flow for the opposite driving force. The inward-rectification is due to a voltage-dependent block of the channel pore by a specific ligand or ligands, and as a result the macroscopic conductance depends on the difference between membrane voltage and the K+ equilibrium potential rather than on membrane voltage itself.

KCNK1, KCNH2, KCNJ12, KCNK6

GO:0005243

MF

gap junction channel activity

A wide pore channel activity that enables a direct cytoplasmic connection from one cell to an adjacent cell. The gap junction can pass large solutes as well as electrical signals between cells. Gap junctions consist of two gap junction hemi-channels, or connexons, one contributed by each membrane through which the gap junction passes.

GJA1, MIP, GJC1

GO:0005244

MF

voltage-gated ion channel activity

Enables the transmembrane transfer of an ion by a voltage-gated channel. An ion is an atom or group of atoms carrying an electric charge by virtue of having gained or lost one or more electrons. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.

GPR89A, CLIC1, CLIC3, CYBB, GPR89B, PKD2, ANO6, TMEM37, CLIC6, KCNK17, KCNK12, CLIC5

GO:0005245

MF

voltage-gated calcium channel activity

Enables the transmembrane transfer of a calcium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.

ITGAV, CACNB3, CACNA2D1, NCS1, PKD2, CACNA1C, GAS6, CACNA1E, TPCN2, CACNG8, CACNG6

GO:0005246

MF

calcium channel regulator activity

Modulates the activity of a calcium channel.

TSPAN13, PRKCB, PLN, SRI, NPY2R, GNB2, GRM3, SGK3, STIM2, NRXN1, HPCAL4

GO:0005247

MF

voltage-gated chloride channel activity

Enables the transmembrane transfer of a chloride ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.

CLCN3, CLCN4, CLCN5, CLCN6, CLCN7, CLCNKA, CLCNKB, ANO6

GO:0005248

MF

voltage-gated sodium channel activity

Enables the transmembrane transfer of a sodium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.

PKD2, SCN9A

GO:0005249

MF

voltage-gated potassium channel activity

Enables the transmembrane transfer of a potassium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.

CNGA1, KCNA1, KCNMA1, KCNH2, KCNC3, KCNJ11, KCNE4

GO:0005250

MF

A-type (transient outward) potassium channel activity

Enables the transmembrane transfer of a potassium ion by an outwardly-rectifying voltage-gated channel that produces a transient outward current upon a step change in membrane potential.

KCNIP2

GO:0005251

MF

delayed rectifier potassium channel activity

Enables the transmembrane transfer of a potassium ion by a delayed rectifying voltage-gated channel. A delayed rectifying current-voltage relation is one where channel activation kinetics are time-dependent, and inactivation is slow.

KCNA1, KCNH2, KCNC3, KCNG3, KCNV2, KCNG1

GO:0005252

MF

open rectifier potassium channel activity

Enables the transmembrane transfer of a potassium ion by an open rectifier voltage-gated channel. An open rectifier current-voltage relationship is one in which the direction of rectification depends on the external potassium ion concentration.

KCNK3

GO:0005253

MF

anion channel activity

Enables the energy-independent passage of anions across a lipid bilayer down a concentration gradient.

LRRC8A

GO:0005254

MF

chloride channel activity

Enables the facilitated diffusion of a chloride (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.

FXYD1, CLIC1, BEST1, CLIC3, CFTR, GABRA5, SLC1A4, SLC26A2, CLCN3, CLCN4, CLCN5, CLCN7, CLCA4, SLC26A11, BEST3, CLIC6, SLC26A1, TTYH1, CLIC5

GO:0005260

MF

channel-conductance-controlling ATPase activity

Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate. An animal enzyme that is active in forming a chloride channel, the absence of which brings about cystic fibrosis. It is also involved in the functioning of other transmembrane channels.

CFTR

GO:0005261

MF

cation channel activity

Enables the energy-independent passage of cations across a lipid bilayer down a concentration gradient.

TRPC1, FAM26F, PIEZO1, CALHM2, TRPV4, GAR1, ASIC3, TRPV2

GO:0005262

MF

calcium channel activity

Enables the facilitated diffusion of a calcium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.

TRPC1, PSEN1, CACNB3, PKD1, GRIN2A, TRPC3, CACNA1E, DENND5A, DENND5B, TRPV1, TRPM4, TMEM37, RYR2, CUL5, TRPM7, PANX1, TRPM6, TRPV6, TRPV4, SLC24A3, TMCO1, TRPC6, TRPV2

GO:0005267

MF

potassium channel activity

Enables the facilitated diffusion of a potassium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.

KCNK1, KCNK3, FXYD4, KCNA1, PKD2, KCNK17, TMEM38B, KCNG1, KCNK6

GO:0005272

MF

sodium channel activity

Enables the facilitated diffusion of a sodium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.

KCNK1, SCNN1G, TRPM4, ASIC3

GO:0005275

MF

amine transmembrane transporter activity

Enables the transfer of amines, including polyamines, from one side of the membrane to the other. Amines are organic compounds that are weakly basic in character and contain an amino (-NH2) or substituted amino group.

AQP9

GO:0005277

MF

acetylcholine transmembrane transporter activity

Enables the transfer of acetylcholine from one side of the membrane to the other. Acetylcholine is an acetic acid ester of the organic base choline and functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions.

SLC22A1

GO:0005280

MF

hydrogen:amino acid symporter activity

Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: amino acid(out) + H+(out) = amino acid(in) + H+(in).

SLC36A1

GO:0005283

MF

sodium:amino acid symporter activity

Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: amino acid(out) + Na+(out) = amino acid(in) + Na+(in).

SLC38A1

GO:0005289

MF

high-affinity arginine transmembrane transporter activity

Catalysis of the transfer of arginine from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.

SLC7A2

GO:0005290

MF

L-histidine transmembrane transporter activity

Enables the transfer of L-histidine from one side of a membrane to the other. L-histidine is 2-amino-3-(1H-imidazol-4-yl)propanoic acid.

SLC38A1

GO:0005292

MF

high-affinity lysine transmembrane transporter activity

Catalysis of the transfer of lysine from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.

SLC7A2

GO:0005308

MF

creatine transmembrane transporter activity

Enables the directed movement of creatine across a membrane. Creatine is a compound synthesized from the amino acids arginine, glycine, and methionine that occurs in muscle.

SLC6A8, SLC16A12

GO:0005309

MF

creatine:sodium symporter activity

Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: creatine(out) + Na+(out) = creatine(in) + Na+(in).

SLC6A8

GO:0005310

MF

dicarboxylic acid transmembrane transporter activity

Enables the transfer of dicarboxylic acids from one side of the membrane to the other. A dicarboxylic acid is an organic acid with two COOH groups.

SLC25A10

GO:0005313

MF

L-glutamate transmembrane transporter activity

Enables the transfer of L-glutamate from one side of a membrane to the other. L-glutamate is the anion of 2-aminopentanedioic acid.

SLC25A12, SLC1A3, SLC1A2, SLC25A13

GO:0005314

MF

high-affinity glutamate transmembrane transporter activity

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glutamate(out) + H+(out) = glutamate(in) + H+(in). In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.

SLC1A3, SLC1A2, SLC1A6

GO:0005315

MF

inorganic phosphate transmembrane transporter activity

Enables the transfer of a inorganic phosphate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport.

SLC20A2, SLC20A1, ANKH

GO:0005316

MF

high-affinity inorganic phosphate:sodium symporter activity

Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: HPO42-(out) + Na+(out) = HPO42-(in) + Na+(in). In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.

SLC20A1

GO:0005319

MF

lipid transporter activity

Enables the directed movement of lipids into, out of or within a cell, or between cells.

APOE, APOA2, APOD, GM2A, SLCO2A1

GO:0005324

MF

long-chain fatty acid transporter activity

Enables the directed movement of long-chain fatty acids into, out of or within a cell, or between cells. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22.

FABP3, ABCD3

GO:0005328

MF

neurotransmitter:sodium symporter activity

Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: neurotransmitter(out) + Na+(out) = neurotransmitter(in) + Na+(in).

SLC6A1, SLC6A6, SLC6A8, SLC6A14

GO:0005329

MF

dopamine transmembrane transporter activity

Enables the transfer of dopamine from one side of the membrane to the other. Dopamine is a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.

SLC22A1, SLC22A3

GO:0005332

MF

gamma-aminobutyric acid:sodium symporter activity

Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: gamma-aminobutyric acid(out) + Na+(out) = gamma-aminobutyric acid(in) + Na+(in).

SLC6A1

GO:0005333

MF

norepinephrine transmembrane transporter activity

Enables the transfer of norepinephrine from one side of the membrane to the other. Norepinephrine (3,4-dihydroxyphenyl-2-aminoethanol) is a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine.

SLC22A1

GO:0005337

MF

nucleoside transmembrane transporter activity

Enables the transfer of a nucleoside, a nucleobase linked to either beta-D-ribofuranose (ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleotide) from one side of a membrane to the other.

SLC29A1

GO:0005338

MF

nucleotide-sugar transmembrane transporter activity

Enables the transfer of a nucleotide-sugar from one side of the membrane to the other. A nucleotide-sugar is any nucleotide in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative.

SLC35D2, SLC35E3

GO:0005344

MF

oxygen transporter activity

Enables the directed movement of oxygen into, out of or within a cell, or between cells.

HBB, HBG1, HBA1, CYGB, IPCEF1, NGB

GO:0005345

MF

purine nucleobase transmembrane transporter activity

Enables the transfer of purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, from one side of a membrane to the other.

AQP9

GO:0005347

MF

ATP transmembrane transporter activity

Enables the transfer of ATP, adenosine triphosphate, from one side of a membrane to the other.

SLC25A17

GO:0005350

MF

pyrimidine nucleobase transmembrane transporter activity

Enables the transfer of pyrimidine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, from one side of a membrane to the other.

AQP9

GO:0005351

MF

sugar:proton symporter activity

Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sugar(out) + H+(out) = sugar(in) + H+(in).

SLC2A10, SLC35A2, SLC35A1, SLC35A5, SLC2A6, SLC35A3

GO:0005353

MF

fructose transmembrane transporter activity

Enables the transfer of fructose from one side of the membrane to the other. Fructose exists in a open chain form or as a ring compound. D-fructose is the sweetest of the sugars and is found free in a large number of fruits and honey.

SLC2A5

GO:0005355

MF

glucose transmembrane transporter activity

Enables the transfer of the hexose monosaccharide glucose from one side of the membrane to the other.

SLC2A10, PPBP, SLC2A1, SLC2A3, SLC2A4, SLC2A5, MFSD4B, SLC2A14, SLC2A6

GO:0005369

MF

taurine:sodium symporter activity

Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: taurine(out) + Na+(out) = taurine(in) + Na+(in).

SLC6A6

GO:0005372

MF

water transmembrane transporter activity

Enables the directed movement of water (H2O) from one side of a membrane to the other.

AQP9, AQP2, SLC14A1

GO:0005375

MF

copper ion transmembrane transporter activity

Catalysis of the transfer of copper (Cu) ions from one side of a membrane to the other.

ATOX1, SLC31A1, SLC31A2, SLC11A2

GO:0005381

MF

iron ion transmembrane transporter activity

Catalysis of the transfer of iron (Fe) ions from one side of a membrane to the other.

SLC11A2, TTYH1, SLC40A1

GO:0005384

MF

manganese ion transmembrane transporter activity

Catalysis of the transfer of manganese (Mn) ions from one side of a membrane to the other.

ZP3, SLC11A1, SLC11A2

GO:0005385

MF

zinc ion transmembrane transporter activity

Enables the transfer of zinc (Zn) ions from one side of a membrane to the other.

SLC39A6, SLC39A14, SLC39A4, SLC30A8, SLC39A8, SLC39A10, SLC30A1

GO:0005388

MF

calcium-transporting ATPase activity

Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Ca2+(cis) = ADP + phosphate + Ca2+(trans).

ATP2A2, ATP2B1, ATP2B4, ATP2C1

GO:0005391

MF

sodium:potassium-exchanging ATPase activity

Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Na+(in) + K+(out) = ADP + phosphate + Na+(out) + K+(in).

ATP1B1, ATP1A2, ATP12A, ATP1B3

GO:0005415

MF

nucleoside:sodium symporter activity

Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: nucleoside(out) + Na+(out) = nucleoside(in) + Na+(in).

SLC28A3

GO:0005427

MF

proton-dependent oligopeptide secondary active transmembrane transporter activity

Catalysis of the transfer of a oligopeptide from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by proton movement.

CDH17

GO:0005432

MF

calcium:sodium antiporter activity

Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + Na+(out) = Ca2+(out) + Na+(in).

SLC3A2

GO:0005436

MF

sodium:phosphate symporter activity

Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + phosphate(out) = Na+(in) + phosphate(in).

SLC20A2, SLC20A1

GO:0005451

MF

monovalent cation:proton antiporter activity

Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: monovalent cation(out) + H+(in) = monovalent cation(in) + H+(out).

SLC47A1

GO:0005452

MF

inorganic anion exchanger activity

Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: inorganic anion A(out) + inorganic anion B(in) = inorganic anion A(in) + inorganic anion B(out).

SLC4A2, SLC4A8, SLC4A4

GO:0005456

MF

CMP-N-acetylneuraminate transmembrane transporter activity

Enables the transfer of a CMP-N-acetylneuraminate from one side of the membrane to the other.

SLC35A1

GO:0005459

MF

UDP-galactose transmembrane transporter activity

Catalysis of the transfer of a UDP-galactose from one side of the membrane to the other. UDP-galactose is a substance composed of galactose in glycosidic linkage with uridine diphosphate.

SLC35A2

GO:0005461

MF

UDP-glucuronic acid transmembrane transporter activity

Catalysis of the transfer of a UDP-glucuronic acid from one side of the membrane to the other. UDP-glucuronic acid is a substance composed of glucuronic acid in glycosidic linkage with uridine diphosphate.

SLC35D1

GO:0005462

MF

UDP-N-acetylglucosamine transmembrane transporter activity

Enables the transfer of a UDP-N-acetylglucosamine from one side of the membrane to the other. N-acetylglucosamine is a substance composed of N-acetylglucosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate.

SLC35A3

GO:0005477

MF

pyruvate secondary active transmembrane transporter activity

Catalysis of the transfer of pyruvate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport.

SLC16A7

GO:0005483

MF

soluble NSF attachment protein activity

Interacting selectively and non-covalently with both N-ethylmaleimide-sensitive fusion protein (NSF) and a cis-SNARE complex (i.e. a SNARE complex in which all proteins are associated with the same membrane) and increasing the ATPase activity of NSF, thereby allowing ATP hydrolysis by NSF to disassemble the cis-SNARE complex.

NAPB

GO:0005484

MF

SNAP receptor activity

Acting as a marker to identify a membrane and interacting selectively with one or more SNAREs on another membrane to mediate membrane fusion.

SNAP23, GOSR2, STX7, STX6, VAMP4, SEC22B, STX11, SNAP29, STX2, VAMP7, SNAP25, VAMP2, STX4, STX3, VAMP3, SEC22A, BET1L, VTI1B

GO:0005487

MF

nucleocytoplasmic transporter activity

Enables the directed movement of substances between the nucleus and the cytoplasm of a cell.

XPO1, TPR, NUP62, NUP153, NUP107, NUP160, NUP35, NUP58, UPF3A, NUP62CL, RBM22, NXF1

GO:0005496

MF

steroid binding

Interacting selectively and non-covalently with a steroid, any of a large group of substances that have in common a ring system based on 1,2-cyclopentanoperhydrophenanthrene.

PGRMC2, ESR1, NR3C1, SHBG, PGR, CYP3A4, CYP21A2, AR, ESRRA, HSD11B2, PAQR8, ESR2, GPER1, PAQR5

GO:0005497

MF

androgen binding

Interacting selectively and non-covalently with any androgen, male sex hormones.

ALDH1A1, SHBG, AR, TSPO

GO:0005499

MF

vitamin D binding

Interacting selectively and non-covalently with vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).

GC, KL

GO:0005501

MF

retinoid binding

Interacting selectively and non-covalently with retinoids, any member of a class of isoprenoids that contain or are derived from four prenyl groups linked head-to-tail. Retinoids include retinol and retinal and structurally similar natural derivatives or synthetic compounds, but need not have vitamin A activity.

RBP1, PTGDS

GO:0005504

MF

fatty acid binding

Interacting selectively and non-covalently with fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.

NDUFAB1, APOC1, PMP2, ALB, FABP4, NME2, PTGDS, FABP5

GO:0005506

MF

iron ion binding

Interacting selectively and non-covalently with iron (Fe) ions.

PLOD2, SCD, P4HA2, CYP27B1, CYP26A1, SC5D, ETHE1, CH25H, FTL, FTH1, CYP1A1, CYP17A1, CYP11A1, CYP2E1, MFI2, CYP3A4, CYP21A2, ALOX5, FDX1, CYP2D6, CYP2A6, CYP19A1, CYP2C9, P4HA1, CYP11B1, ALOX15, CYP11B2, CYP2B6, CYP3A5, CYP3A7, CALR, NOS3, XDH, ABCE1, HBB, HBG1, HBA1, LCN2, PLOD1, AOX1, MSMO1, PTGIS, CYP1B1, CYP51A1, JMJD6, OGFOD3, CYP2R1, KDM7A, CYP4V2, FA2H, CYP2U1, SCD5, MINA, P3H2, TPH2, CYP2W1, CYGB, ACO2, ADI1, EGLN3, CYP3A43, CYP26B1, NFU1, CYP8B1

GO:0005507

MF

copper ion binding

Interacting selectively and non-covalently with copper (Cu) ions.

ATOX1, CCS, AOC2, F8, IL1A, ALB, ANG, PRNP, TP53, SOD3, F5, TYR, PAM, MT3, LOX, GPC1, SNCA, LOXL1, COX17, AOC3, MOXD1, COMMD1, LOXL4, P2RX4, S100A13, HEPH, METTL17, PRND, LOXL2, COX11

GO:0005509

MF

calcium ion binding

Interacting selectively and non-covalently with calcium ions (Ca2+).

ESYT2, CIB4, MASP2, MATN2, EML1, NDUFAB1, NCAN, PRRG1, PCDH17, CLGN, PLSCR1, CETN3, DHH, ACTN4, CALU, EDIL3, NOL3, EFCAB14, RAB11FIP3, PDCD6, SLC25A12, SLIT2, CLSTN1, LETM1, GUCA1C, EFEMP2, F2, C1R, LDLR, CRP, APCS, BGLAP, MMP1, ANXA1, S100B, S100A8, CLEC3B, S100A9, S100A6, ANXA2, THBS1, ANXA6, MGP, ANXA5, MMP10, SPARC, ANXA4, C1S, HSPA5, MBL2, ANXA3, ACTN1, MYL4, BMP1, VCAN, TPT1, LCP1, PRKCSH, NID1, PLA2G2A, HSP90B1, MYL6B, ARSA, ATP2A2, PAM, CDH2, MYL12A, CAPN3, SYT1, ENPP1, CALB2, MMP8, FBLN1, MMP11, MYL9, S100P, S100A4, PON1, CALR, CANX, S100A2, SRI, S100A7, S100A11, CDH5, MAN1A1, PRSS3, THBS4, FBN1, FBN2, ACTN2, HPCAL1, SNCA, PLA2G5, EPS15, GPD2, NOTCH1, IQGAP1, PLA2G4A, CD97, COMP, MMP14, ANXA11, PLCD1, MMP15, MMP16, CDH6, CDH11, CDH12, CDH13, CDH15, TPD52, MYL6, S100A10, NCALD, CALM2, NCS1, TPM4, ADAM8, JAG1, NUCB2, DLK1, CRB1, FBLN2, VLDLR, HSPG2, LRP2, MYL7, MYL5, DSC2, NUCB1, DST, NOTCH2, PPP2R3A, PCDH1, PPP3CA, TBC1D8B, ASPH, EFEMP1, FSTL1, CDH17, CBLB, MMRN1, PKD2, ENPP2, NID2, DAG1, DSG2, ADGRE1, RCN2, GAS6, SPARCL1, FAT1, ITPR2, ITPR3, ITPR1, PLS1, MELK, LTBP1, RCN1, RYR3, RGN, ITSN1, CACNA1E, AOC3, PGS1, GNPTAB, EYS, EFCAB2, TBC1D9B, MCTP1, CRELD2, CCBE1, PAMR1, TBC1D9, FBN3, LPCAT2, RASGRP2, NOTCH2NL, SPATA21, NECAB2, S100A7A, C2CD5, SULF2, SULF1, SCUBE1, SCUBE3, FAM20C, MICU2, RASEF, NIN, EFCAB3, USP32, REPS2, DNER, MCFD2, PCDH19, SYTL5, FAT3, STAB2, GPR98, TTN, SPOCK2, EDEM1, RYR2, CCDC47, FKBP10, EFHD2, SYTL4, REPS1, VWCE, S100A16, CALML4, PPP3R2, NECAB3, NOX5, NELL2, MMP19, S100A13, CHP1, CIB1, EGFL8, SPOCK3, AIF1L, SDF4, EFCAB11, SLC25A23, CDHR2, PCDH11Y, PLA2G12A, EDEM3, PCDHAC1, EHD4, TTYH1, SMOC2, CLSTN2, EFCAB1, ADGRL3, PCDH9, SLC24A3, SYTL2, PCDH18, CD248, MMP25, CD93, PLCB1, CRTAC1, MAN1C1, DLL4, DUOX2, DUOX1, PLSCR4, LTBP3, KCNIP2, FKBP14, STAB1, CELSR3, ITSN2, EHD3, SEPN1, DSPP, STIM2, PCDH10, ANXA10, CDH22, SLC25A13, MAN1B1, NRXN1, HEG1, PADI4, HPCAL4, EPDR1, GUCA1B, PCDHGC3, PCDHA7, PCDHA6, PCDHA4, PCDHA12, RPH3AL, MACF1, MYO5A, PCDHB9, PCDHB3, PCDHB14, PCDHA9, PCDHA8, PCDHA5, PCDHA3, PCDHA2, PCDHA13, PCDHA11, PCDHA10, PCDHA1, PCDHAC2, MMP24, FKBP7, PCLO

GO:0005515

MF

protein binding

Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).

UBA6, MED19, CIB4, UBE2QL1, ELOVL7, SH3PXD2B, ZC3H12D, VPS37C, CNOT1, UNC119B, WASH1, NEURL1B, STRA13, BBIP1, MIF4GD, FAM195B, AGPS, UBXN8, DDX39A, ACOT7, MYO1C, SNAP23, HAX1, EYA2, AIP, MASP2, RAB27B, TLR4, APBB1, LGALS8, RNF103, ATOX1, SUPT5H, DFFA, HIP1, CLIC1, WWP2, CDC7, ARNTL, PIK3CD, WASL, FOXN3, IPO5, IGF2BP3, PLK4, MEIS1, EXOC5, NR5A2, NDUFA4, BIN1, KPNA3, KRIT1, SDCBP, NOP56, DDX3X, PEX12, KPNA4, TRIM38, PPP6C, FBP2, UBE2C, ACACB, DLGAP1, PLPP3, ARID1A, BHLHE40, SOCS2, CDK2AP1, SOCS3, SOCS6, TRAFD1, DYNC1I1, COPE, CTDSP2, CCS, GOSR2, TOR1A, ADAM10, ENC1, ITGB1BP1, MAP2K7, ACOT8, PDCD5, CHEK1, TPP1, NDC80, TNPO2, MSTN, TSPAN4, IRF6, TAX1BP3, PCDH17, TIMM23, CASK, EREG, AURKA, RAB29, PPP1R12A, XPO1, PIP5K1B, U2SURP, ANKRD28, SMAD7, FYB, NPC1, ANGPT2, SCAMP1, SCAMP2, KPNA5, ARPC2, ARPC3, MDM4, POLR1C, PLSCR1, AXIN1, CETN3, UBD, GSTA4, NPHP1, FANCG, OGT, GRM6, SIVA1, PMM2, INPP4B, MID1, HMGB3, GPR37, HDAC3, BIRC5, STX7, TOX3, FOXP2, TLR3, MAGEB4, INSIG1, NUPL2, CFLAR, SOCS1, MAFG, ZSCAN9, DHX15, ASAP2, ZBTB24, PSMD3, RBFOX2, SIAH2, ZNHIT1, MAP3K13, DAPK3, TGFB1I1, AP5Z1, CTIF, MAP3K7, DHH, RIPK2, HOXA3, PRPF3, COCH, CBFA2T2, PPIH, OIP5, RAD51C, MED7, ATP8B1, BCL2L11, FOXO3, SPRY2, SPRY1, CHMP2A, TSPAN6, PLRG1, PRC1, ZNF207, BUB1, BUB3, ACTN4, TRIAP1, TRAF3IP2, STX6, SGTA, SSNA1, SLC25A17, NUDT21, C21orf2, NRDC, CALU, AHCYL1, ORC5, TYROBP, PDE6D, RAD21, PPP1R12B, BNIP3L, PARK2, SMARCA5, SPAG9, KIF5C, NUAK1, TRAK2, OPA1, ZEB2, PIP5K1C, KIF1B, KDM1A, FZD6, PPL, BRINP1, PLXNC1, SNX3, SORBS3, GMDS, CCNT1, GREM1, BUB1B, EIF4E2, CCNT2, TLR2, TSPAN2, EXOC3, RAD1, REV3L, JAK2, PRMT3, SRPX2, LPXN, CTNND1, SLC19A2, PFKFB2, PQBP1, DKC1, TRIM13, EDF1, BRD4, RAMP1, RAMP3, TBL1X, NBN, NOL3, MITF, ADAM23, LDB3, ROCK2, MFAP3L, ATG13, OBSL1, ZC3H11A, RAB11FIP3, SOCS5, CNOT3, SIN3B, DNAJB6, LRP5, GADD45B, NDUFS2, ZPR1, USP12, SEMA7A, PDCD6, ATP6V1G1, VPS4B, MPDU1, ZNF217, H2AFY, FLNB, NCOR1, VAMP4, PEX14, ULK1, TULP3, SEC22B, PRPF40A, TACC1, POLQ, VPS26A, ERN1, LGR5, PSIP1, SRSF10, GMNN, CLN5, HSBP1, KHDRBS3, TADA3, BANF1, STX11, PRKRA, LRP6, USP2, OFD1, PPM1B, ADAP1, UTP20, RP2, WDHD1, RAD51D, BCAR3, POP7, PSMD10, TRAPPC6A, STAM2, TUSC2, RASSF9, FLOT1, CLPX, NEBL, RNF8, CIAO1, SLC22A5, PDE9A, SRP72, URI1, USP1, TPPP, SLIT2, ATG12, TOX4, SEC24D, SUPT7L, FCHSD2, UBXN7, ERLIN2, DKK1, GLS, RHOBTB3, TRIM37, SEC31A, CLSTN1, CEP152, HEXIM1, CCNB2, UBR5, FSBP, MFN2, IKBKAP, OAZ2, CSPG5, LETM1, SNX4, ZWINT, LUC7L3, KIF20A, KIF4A, MBD4, GADD45G, TNKS, VAPB, SNAPIN, SMC2, FARS2, ZBTB7A, BMP10, CD2BP2, PARN, PSMG1, ABCA1, TDP2, POLR1A, PCNT, YEATS4, CNOT4, STAMBP, NFATC1, EYA4, APBB3, SNAP29, FGF19, LSM8, WIZ, STAU1, MAP4K4, AIFM1, CLIC3, LATS1, DDAH2, CBX7, EFEMP2, MBD3, PTTG1, BCL10, NDUFB10, ZBED1, PEX11B, ACTL6A, CCNE2, WHSC1, LDHA, F8, EGFR, F2, HP, PLG, PLAU, PLAT, ADA, CA2, SPINK1, SERPINC1, SERPINA1, SERPINA3, AGT, A2M, C3, TIMP1, CST3, KNG1, FOS, MYC, PDGFB, LDLR, TGFA, TGFB1, NGF, PRL, GH1, INS, IGF2, TNF, IL1A, CD4, COL1A1, COL3A1, CRYAB, LMNA, APOA1, APOE, APOA2, FGA, FGB, FGG, CRP, APOH, FN1, RBP4, TTR, ALB, TFRC, TF, FTL, FTH1, MT2A, ESR1, ANG, SLPI, VTN, HMGCR, RAF1, ANXA1, PDGFA, APOB, NR3C1, MYCN, KRT1, S100B, VWF, GAPDH, ERBB2, NTRK1, TP53, CYBB, GNAI2, GYPC, IGF1, ATP1B1, APP, APOD, ITGB3, ITGB2, S100A8, INHA, SERPINE1, SLC25A5, SERPINA5, SERPING1, CFI, ISG15, ALPL, EIF2S1, IL6, ICAM1, RPLP1, RPLP0, SCG5, JUN, FABP3, SSB, ITGB1, PRKCB, KRT18, KRT8, INSR, FYN, RB1, PGR, PTMA, CDK1, S100A9, S100A6, EIF4E, ENO1, NPM1, TPM3, ITGAV, LPL, SERPINE2, TH, LDHB, P4HB, KLK3, ANXA2, TUBB, ADRB2, DCN, PSAP, CTSL, PFN1, EPRS, CTSB, HSP90AA1, HNRNPC, UQCRH, LYN, ERCC1, THBS1, IGF1R, COL1A2, ANXA6, CD55, SLC3A2, HSP90AB1, SOD3, MME, INHBA, MGP, CD14, PTPRC, MET, MFI2, ADRB1, CFH, ITGA5, VIM, KRT19, KRT7, GNAI3, KRT16, RPSA, IL6R, SNRPA, FGF2, HOXB5, GSTP1, CST2, SNRPC, CD48, LGALS1, HMGB1, PAEP, FBP1, SPARC, INHBB, WNT2, HMOX1, PDGFRB, HNRNPA1, SNRPA1, CTSH, FGR, PARP1, POLA1, ALOX5, ALDOC, H2AFZ, HIST1H2AG, FBXO45, UBC, TRAPPC2, HSPA1A, HSPA1B, GLI2, GLI3, RAP2A, SRGN, CXCL8, CCL3, MYBL2, AR, RRAS, HIST1H1E, BCL2, SPP1, DLAT, NR2F1, TXN, COX5B, MAPT, PRKAR1A, KIT, CD28, HSPD1, THRA, CLU, GHR, IRF1, HSPA5, EGR2, SLC2A1, PDHB, ITGAM, PYGB, PYGM, MBL2, RALA, RALB, LAMP1, FGFR1, TOP1, TOP2A, VDR, ESRRA, PC, DMD, SFTPC, IGF2R, CDK4, PRPS2, ODC1, PCNA, SLC25A4, F5, TPR, CKB, FCGR1A, BMP2, BMP4, BCKDHA, SKI, ACTN1, XRCC5, UNG, IFITM1, GP1BB, CCL4, TDGF1, LAMP2, RNH1, CCL5, CFTR, EEF2, PDIA4, P4HA1, TPT1, GYS1, PRKAR2A, ADRB3, GTF2F2, SELL, MIF, HGF, HCLS1, DRD2, PKM, HSP90B1, CCNB1, MYL6B, SLC2A4, SNRPB, TYR, IDE, IL1R1, MMP9, POU2F1, HNRNPL, DARS, ETS1, JUP, ETS2, PVR, GSPT1, ARSA, EZR, FOSL1, FOSL2, VAV1, AREG, CD46, NME1, VEGFA, HIVEP1, RPS2, CHN1, TCF4, ST6GAL1, TCF3, DSP, MUC1, ALOX15, H2AFX, PFKFB1, ITGB4, CREB1, PDGFRA, PECAM1, HIST1H1C, EPCAM, SELE, ATP2A2, CD36, PLCG2, ZNF20, ZNF24, HMGA1, TMEM11, IFNAR1, PRKCA, JUNB, ITGA2, GJA1, UBTF, JUND, TAL1, ATF7, PRKACA, DES, CEBPB, PTPN2, DDX5, PFKL, LGALS3, IGFBP3, PSMC3, TCP1, ERCC2, RPL35A, ITGB5, ARF4, ADRA2B, RPL7, EGR1, SON, RPL17, RCC1, SDC1, ATF1, ATF3, ATF4, ATF6, PAM, EPOR, CD58, POLR2E, CD53, ELK1, TNNI3, WT1, NFKB1, NCF2, FST, ATP2B1, CD33, CCNA2, TNFRSF1B, RAB3B, RAB5A, NR1D1, MSH3, PSMB1, ITGAX, BCL3, MAK, HNF1A, EFNA1, RASA1, MAL, FLNA, AGXT, SYT1, TNFAIP3, SAT1, ZP3, FGFR2, ERBB3, SDHB, CD9, BCKDHB, TGM2, OSBP, IL10, SCP2, UBA1, NME2, ENPP1, GAL, HNRNPA2B1, NR4A1, CA4, MRC1, XPA, ITGA6, SFPQ, TUBG1, PPIB, ANOS1, JAK1, PTPRB, PTPRD, SP100, AHCY, CFL1, ATP2B4, FSHR, IL32, IL4R, NR2F2, GADD45A, EEF1B2, IGFBP5, POLR2A, CDK2, APC, CD24, ADRA1D, F2R, MCM3, NFYB, AZGP1, BRD2, FAS, YY1, DNAJB1, MT3, PSMA1, PSMA2, PSMA3, PSMA4, LMO2, S100P, ITGA3, PTX3, CTNNA2, DNMT1, RPL13, S100A4, HMGB2, PTBP1, TARS, ZFP36, PLN, KLRC1, CD27, MST1, ACVR2A, MAPK3, G0S2, DPP4, ARNT, RPL10, CALR, CANX, IL1R2, PIK3R1, PSMB5, GSTM2, ABCD3, LOX, NDUFS1, POLD1, SMARCA1, MAPK1, MZF1, RXRB, RBL1, GRN, PTPRM, S100A2, CTGF, EPHA3, KDM5A, IL12A, CASP1, NOS3, CD40LG, PBLD, PRDX6, ECHS1, PEBP1, PDIA3, PPP2R1A, PPP2R1B, CDC27, CCND2, CCND3, CDC25A, PPIF, HLA-A, AVPR2, LRPAP1, AGTR1, CLIP1, SRI, POLR2B, SDHA, CORO1A, GDI1, S100A7, MAT2A, PRKAR2B, RRM2, SDC4, TIA1, DNAJA1, AKT1, AKT2, HNRNPH3, HNRNPH1, YWHAB, SFN, FCGR2B, CCKBR, OTX2, MC4R, DCTD, GBP1, GTF2H1, STX2, CTH, CDH5, CKS2, HIST1H2BB, TTK, MCM4, MCM5, MCM7, SDC2, SHMT1, HSPA4, GRK5, PRSS3, BTC, USP6, CA8, CTNNA1, CTNNB1, PHB, NF2, RDX, RPA3, RFC4, RFC2, RPL22, GTF2F1, ADM, PTGS2, RORA, PTGER4, THBS4, CBS, FBN1, FBN2, IRS1, AGL, MYH9, ACTN2, BSG, TIMP3, FUS, DDIT3, AHR, FLT4, PSMC2, TRIM23, MAP2K2, RPL4, PPP1CC, BMPR1A, ACVR1B, TGFBR1, LTBR, SERPINB5, SERPINF1, SREBF1, SCNN1A, SRP14, TGFBR2, NUP62, PPARG, HPCAL1, ZEB1, PIGA, TALDO1, SNCA, RBMX, BRCA1, COIL, CDKN1A, FEN1, CAPG, IL6ST, CCT6A, PBX1, MLH1, STAT3, RFC5, RFC3, PMEL, CCNF, EIF2S3, ID1, ETV5, BCL6, RGS2, BUD31, UBA7, PPP1R2, CSK, MAP3K8, ADCYAP1R1, PRKCI, STAT5A, SKIV2L2, PIK3CA, PIK3CB, EPS15, RPS27, ABL2, NCAPD3, LIFR, LRPPRC, CDKN2B, CDKN2C, NSG1, HTT, ECE1, GDF5, CTSK, MATR3, MSH2, SYK, PSMC4, GATA4, NKX2-1, PPIC, CBX5, MAPK8, MAPK9, MKI67, RANGAP1, RECQL, NOP2, ATRX, CRKL, NSF, CDKN1B, NOTCH1, IER3, BRCC3, RPL5, RPL21, RPL28, RPS9, RPS5, RPS10, MAP1B, YAP1, IQGAP1, EIF1AX, ZFP36L2, MTNR1A, ATP5O, LIMS1, NPBWR1, PREP, GLRB, LEPR, SOX9, CD151, IFNAR2, NRIP1, NMU, CSNK1A1, CSNK1D, PIK3CG, CD97, TRPC1, MAPKAPK2, SLC11A2, FASN, CDK8, DHPS, CCT3, CDC34, CENPA, CENPF, SRP9, UBE2A, PPM1F, HOXA1, CSNK1E, ARL4D, PSMB3, MCM2, COMP, TMED10, RBM25, CLK2, VEGFB, PSEN1, NUP153, RANBP2, PSEN2, TSC2, GSK3B, SEPHS1, CDKN1C, MRE11A, AGTR2, GNAQ, MEOX1, MMP14, GDI2, EMD, SERPINB9, PDLIM4, MXI1, ASCL1, TNFSF10, KNTC1, PPT1, CCT8, ATP1A2, ANXA11, PAPOLA, FXR1, RAB5C, RAB7A, RAB9A, RAB27A, SCNN1G, DAP3, ZNF83, DNA2, SMARCA2, SMARCA4, BCAP31, BRCA2, IRAK1, CAV2, PSMD7, STAT5B, USP11, CLCN3, VAMP7, PRKX, NR0B1, NEK2, CCNG1, HNRNPA3, HNRNPM, KPNA2, KPNA1, POLR2J, MAP2K6, ARHGDIA, ARHGDIB, AGFG1, STAT2, GTF2A1, GTF2A2, MSH6, ZNF136, RBM5, EFNA4, MRPL12, NDST1, HMGA2, PLK1, DAPK1, CEBPG, RABGGTB, AP2S1, TTC3, PLA2G16, IST1, POLG, BLM, RARS, HIRA, ATXN3, ATXN1, ATN1, TERF1, OAZ1, YARS, PRKAG1, PRKAA2, RAD23A, RAD23B, EPHB4, EPHB1, EPHA4, GAS1, EMP1, EMP2, EMP3, EIF5, GEM, RRAD, NR1H2, CSE1L, VCP, HADHB, F2RL1, MLLT10, NAP1L1, CASP9, CASP6, CDH15, FOXG1, TPD52, SEC13, SNU13, GFER, HNRNPH2, SUMO3, EIF3B, BID, POLE2, AP1S2, HDAC4, EIF6, CTBP2, PEX3, SYNJ2BP, GEMIN4, KLF3, NUP107, SESN2, FOXL2, ANTXR2, ADAMTS12, TIRAP, ARPC4, CD81, PTEN, PPP4C, GABARAPL2, ACTB, RAC3, EIF4A1, SNAP25, PRPS1, SHFM1, S100A10, CDC42, DSTN, SRP54, RAB2A, RAB5B, CKS1B, CXCR4, UBE2D3, UBE2M, ABCE1, RPS3A, RPL26, PSME3, RPL15, ATP6V0D1, RPL37A, RHOA, NCALD, HSPE1, SEC61A1, STXBP1, B2M, TGFB2, NPC2, PKIA, SUMO2, DCAF7, LMO4, NUTF2, USP46, RPS7, PPP1CA, PPP1CB, CALM2, NCS1, PSMC1, RPS15A, UBE2H, YWHAE, RPS14, RPS18, RPS13, SNRPF, LSM3, LSM6, SNRPD1, SNRPD2, SNRPD3, BTG1, TMSB4X, PSMC6, RPL7A, RAB11A, PPP2CB, RPL23A, RPS6, HIST1H4A, RAB1A, RAP1A, RPS25, RPS26, RBX1, GNB2, RPL30, RPL31, RPL10A, RPL11, PPIA, RPS27A, UBA52, GRB2, TRA2B, RAC1, AP2B1, VAMP2, GNAI1, YWHAZ, UBE2B, SNRPN, DYNLL1, DYNLT1, SKP1, EIF5A, RACK1, ACTG1, UBE2I, YBX1, TPM4, EEF1A1, TUBA1B, TUBA4A, HIST1H3D, HBB, HBA1, CXADR, IGBP1, ADAM8, RPP30, GTF2I, DLG4, PIP4K2B, SRPK2, CCT2, JAG1, PRKDC, ADAM17, BLOC1S1, BTG2, ELF3, NTHL1, MAP1A, CRADD, ADARB1, MT1H, MT1X, GPSM2, SLC7A9, SARNP, HTRA3, RPL24, RPL36A, CBX1, SMAD3, ARF1, ARF5, ERH, RPL19, H3F3A, GNAS, TNFAIP6, SHC2, DAB2, VLDLR, HSPG2, PKD1, LRP2, XIAP, FOXO4, RBM3, CYCS, MPP1, GTF2B, CDK6, CDK5, CDK16, PURA, HSF1, REEP5, HNRNPU, IRF9, MDM2, SPTBN1, E2F1, SET, SRSF2, RUNX1, PMP22, FABP5, ANK2, IL1RL1, DR1, MC2R, XPC, EWSR1, POU5F1, COL4A3, OCRL, ROR1, MEF2A, CENPE, KIF23, ID2, APBA1, SP3, DSC2, ID3, RPL18A, MAP2K1, TEK, FKBP4, GUCY2D, CREB5, DST, HHEX, GNA12, CAV1, TGFBR3, PLAUR, COL10A1, RELA, NOTCH2, TLE1, TLE3, PRKCQ, ACVR1, AKR1C1, REL, CD164, YWHAH, PTK2, LIPE, ZBTB16, SRSF11, PRKCD, RNASEL, DUSP2, PTPN11, PPP2R3A, EXOSC9, MEF2C, TYRO3, APLP2, SULT2A1, RING1, RAD51, PAX8, FMR1, PRDX1, SOX4, C1QBP, COL16A1, TJP1, ZFP36L1, KHDRBS1, BAX, MCL1, PPARA, SOS1, SOS2, TNK2, SRSF1, FOXM1, AES, PPP3CA, IL10RB, DDR1, GOLGA2, CD47, PPID, SSRP1, ZNF844, DMPK, RBBP4, NCBP1, KCNA1, EP300, AHNAK, ARL16, HSPA14, AP1B1, CPSF1, BST2, NUP160, SREBF2, ARHGEF5, FOXO1, TBL3, KCNMA1, ASPH, TFCP2, AKAP13, EFEMP1, KCNH2, TROAP, CDC20, FSTL1, STX4, MERTK, GRIN2A, HYAL2, TRIM26, ILF2, ILF3, PTPRJ, EPS8, FOXC1, ANK3, DLG1, TAF10, MYO1E, BNIP3, CSTF3, TIAM1, MALL, AKAP6, STRN3, STK4, TRAF1, ZBTB17, CHAF1A, NR1H3, CALCOCO2, EIF2B5, TARDBP, FADD, MAP2K5, MAPK7, PAK2, CBX3, CBLB, PSMD2, MMRN1, GPS2, SELENBP1, SRSF9, SRSF5, SRSF6, MAD2L1, PTGDR, TRIM28, STX3, G3BP1, CLN3, NMI, PTK7, SKP2, GRB10, MTA1, PPIL2, PPP2R5C, PDE3B, PDCL, MAPK8IP2, UBE2V1, ORC1, ILK, IKZF1, SNTA1, SNTB2, XRCC4, UNC119, OS9, GOLGA4, ADAM9, MYO9B, NFATC2, GAB1, SMAD4, BIRC3, PICALM, MTM1, SQSTM1, MED21, TRPC3, PRPF4B, EIF4EBP1, EIF4EBP2, RIPK1, HDAC1, CAMK2D, DCTN2, PKD2, NAE1, DGKZ, SNX1, MTMR2, CUL2, CUL3, CUL4A, CUL4B, TP53BP2, PTCH1, RAB32, FHL1, ACVR2B, ALCAM, RUNX3, PMAIP1, EXOSC2, BMPR2, SNTB1, GTF2H2, C1D, RAPGEF1, CACNA1C, RUNX2, CBFB, NFYC, CDK13, CKAP5, CIRBP, CAMK1, HNRNPD, TOB2, NID2, DAG1, BOP1, SEPT6, EIF3A, ARHGEF7, SPIDR, GIT2, TFDP1, DCTN1, NPAT, E2F2, EIF2B1, EIF4A2, SELPLG, CTTN, TRIM25, FASTK, FLNC, GAS6, HES1, SLBP, RBM39, NEDD9, FAT1, MCM6, ITPR3, MXD4, NBR1, ITPR1, PUM1, ESPL1, MDC1, KANK1, MELK, SMC1A, GSE1, DIP2A, LTBP1, CASP8, KIF22, MEF2D, CHD4, ARID5B, DRAP1, KPNB1, NR1D2, CUL7, FRMPD4, NCAPH, KIAA0101, EMC2, WTAP, MORF4L2, SEPT2, SART3, NCAPD2, SUZ12, EXOSC7, TRAM2, JOSD1, ARL6IP1, KARS, RRS1, POLD3, KIF14, POSTN, EEA1, NCF4, PDIA6, PAFAH1B3, PCOLCE, PEA15, CDK10, PRKD1, PCM1, PPP2R5A, PTGES3, STK38, NECTIN1, NONO, PTPRK, RABEP1, RNPS1, RBBP5, ERBB4, RALBP1, ZMYND11, ANKRD1, TMED2, PCBP1, TCEB1, TCEB2, UBE3C, TOMM20, PUM3, DLGAP5, TLR1, SEC23A, SHB, NR0B2, STIL, FCN2, SPA17, TAF5, TAF11, MAPRE2, TEAD4, TEAD2, TAF1A, TGFBI, NCOA2, DIXDC1, TRADD, TSN, TRIP11, TRIP13, TRIP6, TWIST1, MAPRE1, TSC22D1, ELAVL1, KISS1, TAB1, SLC1A5, MPPED2, NCOA1, SMAD2, SMAD1, ITSN1, UBE2V2, STK11, STXBP2, CCDC85B, VAMP3, NEDD8, ADIPOQ, USF2, RAB11B, EZH2, ZFHX3, ZYX, ZNF124, HSPB2, SEPT7, ADRM1, CCDC6, IGFBP7, PDCD2, SLC15A2, PKN1, PKN2, TAF12, CRY1, MAPK14, CDC37, DPYSL2, FXN, OCLN, DBN1, PTGIS, NFIL3, HIF1A, IFI16, CDKN3, CLPP, UGP2, AOC3, ATP6V1F, TPD52L1, LONRF1, SWI5, PDS5A, ZNF423, KIZ, QRICH1, HFE, FAM161A, TKFC, TBRG1, TIMM50, LGALSL, ANO6, MRPL51, AMOT, C4orf46, PDCD4, CEP55, NCBP3, KLHL12, PLEKHO1, HSD17B12, CDCA8, SGOL2, CCDC93, PAN3, TMEM97, ODF2, ZNF326, TTMP, NOM1, PDZD11, CENPW, DNAJC21, SGOL1, FAM76B, DOCK11, TJAP1, GNAS, BRMS1L, LDLRAP1, PLEKHS1, FNBP1L, UBR4, ARHGAP21, AVPI1, PHF19, RBM26, WLS, CPSF3L, DCAF8, COL13A1, DEPDC1, ATPAF1, CROCC, CDC42BPA, PDE4DIP, ARHGEF16, SHE, LRRC16A, CD276, TNS2, KANK2, ICE2, CEP135, TBC1D9B, INTS3, ANKRD40, ATL3, TTC19, SFRP4, ZFAND6, OTUD7B, LAIR1, THOC7, SIGIRR, LAMTOR1, JADE1, PTCRA, NIPBL, CXorf57, JMJD6, FAAP20, PTRF, MAST2, FAM117B, TATDN1, MTFR2, NFRKB, KLC3, LRRC8B, RFWD3, KLHL35, PSRC1, BORA, SHQ1, SPSB3, BRAT1, ZC3H14, LARP1, RICTOR, AGTRAP, FIP1L1, MOXD1, C6orf89, OLFM4, PLXDC2, APOOL, ATF7IP, RAD9B, MPRIP, HACD2, RNF111, CCDC141, RBPMS2, TBC1D9, C11orf57, PHLPP2, BBS12, USP34, RAPH1, IKBIP, KCTD1, RPS27L, CBLL1, NOL8, SUPT6H, RUFY3, RHOU, DHX30, CYFIP1, MCM10, COPS6, EPM2AIP1, DHX32, RAB11FIP2, CXXC5, SETX, NOTCH2NL, ZFYVE16, TMC6, NUFIP2, RNF144B, MAVS, NPHP3, COMMD6, WAPL, SPRED1, RBBP6, NECAB2, TECPR1, HUWE1, NEK8, SDCCAG8, ZBTB33, TMEM150A, PEG10, SYVN1, TTC7B, PABPN1, MTDH, MAGI2, RTN4RL1, NOXA1, ALYREF, CD163, TAX1BP1, CAND1, HOOK3, LONP2, NLRC5, CHD1L, GPBP1, RPS19BP1, CARM1, COMMD2, ANKLE2, CEP57, CACUL1, KIF18B, KMT5C, HOMER1, GATAD2A, DCP2, TMPRSS6, ERC1, ZDHHC17, CRLF3, SIAH1, TRAPPC5, CREBRF, FOXP4, MAP4K3, NOSTRIN, CCDC103, CARKD, FAM114A1, LRRC8A, CHERP, TRIM42, BBS7, WWC1, CCAR1, SLF2, SCUBE3, SKA3, DNAJC10, TP53INP2, SIRT2, FAM20C, TMEM183A, SMC5, YAF2, AMOTL1, SUPV3L1, FANCM, ZNF440, C1orf174, TRIM22, C6orf165, HACE1, MICU2, ZBED8, KIAA0319L, ZNF101, KMT2E, SCYL3, XRN1, UNC5B, ABI1, NLGN4X, SPG20, CNTROB, AHI1, CCAR2, VPS52, NUP93, CRIPAK, CFAP52, ARHGAP24, APITD1, AGGF1, ASCC3, CLIP4, PPM1K, MPP5, FNBP4, ZCCHC7, NIN, MINK1, ZNF276, TAB3, NKAP, CISD2, RPP25L, TBC1D19, COMMD1, RNF182, EID2, NATD1, CD177, ZNF655, KIAA1958, JMY, BANP, EIF1AD, SREK1IP1, IQUB, FAM73A, ZBTB38, FAM184A, GOLM1, PCSK9, POC1A, SPC24, SLC38A9, INO80E, SERBP1, KCTD6, HJURP, C11orf65, SMG8, TNRC6A, CPEB3, ABCF1, BVES, PIK3C3, MCPH1, ARMC2, APPL2, VPS37A, ZMIZ2, ZNF397, TMEM185A, FLCN, NUP43, NUP37, NUP35, REPS2, GPRC5A, BBS1, SPTSSB, DNER, MYRIP, FBXO18, CASC5, NPB, SVIP, ATL2, CEP70, TPCN2, THOC2, INADL, CTCFL, KIF18A, RP9, C1orf216, KCNG3, GADD45GIP1, WDR48, RHEBL1, GABPB2, BBS10, TTC8, MPLKIP, SMARCC2, ZNF420, UHMK1, OSR1, DEPTOR, PUM2, ZCCHC10, TBC1D16, ZNF502, ZNF564, TBC1D15, POC1B, SPATA18, ENOX1, LRRC20, PIFO, PNPT1, SPPL3, SPPL2A, HM13, AGR3, BICD2, NEK9, MGARP, LRRC8C, RB1CC1, MICAL1, PXYLP1, RNF128, SH3RF2, UTP15, GEMIN5, FBF1, RAPGEF6, PARD3, IPO4, FNIP1, UBASH3B, DUSP19, SETD7, SCARB1, THAP3, FRS2, ZC3H15, RAB2B, PPP1R13L, HDAC7, CEMIP, PTPMT1, PDCD6IP, FBLIM1, BLNK, TRIM41, MITD1, ZFAND2B, CHTF18, TMEM170A, SKA2, TNFAIP8L1, UBLCP1, ZFPM2, APH1B, KCNE4, PHIP, RASSF5, PRPF31, EDARADD, PALLD, METTL21A, GEMIN6, ATRIP, PSPC1, GPR98, SYNE2, NANOS1, PPM1E, MYLIP, KAT6B, RSPH1, KCTD13, TTN, RFFL, RAPGEF4, SEC14L1, CPT1B, GBF1, RTF1, TOPBP1, ELMO1, BAP1, FAM168A, NR4A3, NDRG1, DOCK2, TBC1D5, EDEM1, NUP205, APPBP2, ANKS1A, NSMAF, PIGK, SORL1, ANP32B, ESR2, TFG, RYR2, GTF2H4, HDAC2, STAM, PROX1, CREBBP, KAT6A, SYMPK, N4BP2L2, TAF15, GOLGA1, NRCAM, KAT2B, RPGR, INPP5D, DDX17, BCL2L2, TANK, KIFAP3, APBB2, RAD50, ERCC4, UFD1L, HPS1, GATA6, FGF13, FGF14, SMARCC1, RAB8B, BAD, KHSRP, ARHGEF2, EMG1, GLMN, USP13, CUL5, ATP6V0A1, LPP, RBPMS, EXT2, KISS1R, PRKCDBP, POP5, MYDGF, LOH12CR1, MAL2, PIGT, FBXO32, L3MBTL2, TMEM203, UBE2E3, WBP2, FBXW5, NCLN, TEKT1, PMEPA1, ERGIC1, UTP4, TP53INP1, MARVELD3, EXOC4, JAKMIP2, TTC17, CLUAP1, ACD, PBXIP1, MCUR1, KIAA1143, EME1, RAD51AP1, EXOSC8, BORCS7, ARRDC3, CREB3L1, SKA1, APH1A, ARL8A, TRIM43, UPRT, MOAP1, MIEF2, SYTL4, RPUSD4, HAUS1, FAF2, PLEKHB2, OPTN, AP2M1, TUBGCP3, GPRASP2, REPS1, DNAJC19, MSI2, SPDL1, ELP4, YIPF6, HOOK2, SEH1L, FBXO17, C19orf60, SGF29, MVB12A, PTCD3, CYFIP2, NRBF2, EDC3, CDCA5, STAMBPL1, CPNE2, DTD2, S100A16, OTUB1, DPH3, BICD1, MRPL48, ZNF274, VMP1, AURKB, DCUN1D1, SMARCD1, CDCA7L, DDX27, BORCS6, C5orf30, ZC2HC1A, TONSL, GRAMD3, SH3YL1, MED30, NAF1, INTS4, RBM17, AJUBA, ABHD14B, SEC22A, NSL1, PAWR, RSRC1, ITCH, LOXL4, EAF1, CHAMP1, L3MBTL3, SLC41A2, ZFYVE19, RITA1, ZC3H10, PBK, DNAJC1, ZNF512B, FAM84B, EXOC2, EHMT2, MARK4, PRMT6, DHRS1, CEP19, UBE2E2, C9orf72, PRIMPOL, AK8, PRICKLE1, YTHDC1, KREMEN1, VSTM2L, SPATA13, ZMAT2, ANKRD27, IPO9, NECAB3, INPP4A, UHRF2, NEDD4L, QKI, NEK1, SMG1, KIF20B, DLC1, TEFM, RAB3IP, MTMR9, VPS35, PHF12, HHIP, MAGI1, SPAG5, ZNF300, SNX18, PASK, NR1H4, CIC, MED15, ERGIC2, MCCC1, USP28, FNBP1, TRIB3, TP53RK, RANBP9, CSRNP1, UBL7, SRPK1, SMC6, DCLRE1C, STRBP, ORAI2, ZNF587, CEP89, RSF1, RBM15, SPEN, UHRF1, TCF12, MYCBP, CDC5L, PFDN5, GPER1, MPHOSPH8, PKP4, PIK3R4, P2RX4, S100A13, SCAF11, TEAD3, KLF6, TTC1, CDCA3, PHB2, RAD9A, PKMYT1, CHP1, KIF2C, MAP3K5, FEZ1, LYST, DOK1, HSD17B10, SMAD5, BARD1, HNRNPAB, LITAF, CDC6, NPAS2, MDFI, TXN2, EPAS1, CIB1, CCT7, PRMT1, PKP2, SH3GL2, CITED1, CITED2, RARRES2, VRK1, GDF15, NIPSNAP1, NCAPG, PAIP2, NABP2, ZFYVE21, TCF25, SOST, VIMP, SLF1, DBNDD2, CORO1B, BUD13, ORAI3, UQCC2, GINS4, UTP23, CENPK, RHNO1, FAM64A, CCM2, INPP5K, NDFIP1, SYT11, WAC, PAGR1, TMEM43, TBCD, NDUFAF3, CENPO, DOHH, SPON2, POLR3C, HNRNPUL1, PDCD10, RPP25, HTATIP2, DDX23, APOO, FAM195A, RSRP1, C9orf16, C1orf50, SLC25A23, DUSP26, ADI1, RNF126, SNRNP25, DSCC1, MLST8, PHF20, DUSP23, NUP58, GGACT, GNL3, TIMM21, TIPIN, TMEM106C, NUP85, ELOVL1, KATNAL1, HIRIP3, IFT27, CCDC94, RBM4, CARD10, SSBP3, SORBS1, TRPM6, LGR4, BBS2, BBC3, C1QTNF1, NAA15, PINK1, CLEC7A, TMEM59, OSBPL1A, FANCD2, EMILIN2, BEX2, PACSIN1, HDAC8, CADM1, POLDIP3, CDHR2, NIFK, PARD6B, HELZ2, NUF2, ASPSCR1, UACA, RAB34, WDR11, TBL1XR1, PRKD2, FAM129A, FOXP3, UBXN6, CD244, SPRY4, TRIM9, TRIM6, TRIM2, XPO4, CEP44, STRADB, WDR12, TINAGL1, NDEL1, DERL2, MAP1LC3B, SENP6, ELOVL4, CCDC90B, NIF3L1, CTDSP1, EIF5A2, MFF, NAA50, UBA5, MKRN2, PAIP1, KATNBL1, COMMD4, TOLLIP, USP44, RACGAP1, ENKD1, CCDC113, WWP1, GBP3, GABARAPL1, DDX47, RAB1B, NAPB, DNTTIP1, CSRNP2, SDCBP2, METTL9, TRPV6, UPF3A, CDT1, EHD4, SEMA6A, HSD3B7, BLZF1, SLC38A1, PDCL3, TNKS2, RASSF4, DHX36, HIPK2, ADAMTS10, FOXP1, KCTD10, TXNIP, ACBD3, CENPH, DSN1, CHMP4B, FBXL15, MAP1LC3A, RHOJ, FAM83D, SMARCAD1, FBXO44, RGCC, ZNF335, ELOVL6, FAM96A, OBFC1, ARMC7, RPAP3, EGLN3, GAREM1, DOCK5, METTL17, SUDS3, AUNIP, PHAX, CSRP2BP, NOL11, DDX31, MOB1A, AKTIP, ECT2, PLEKHF2, ZWILCH, REEP1, MED20, ELP3, LIN28A, MEAF6, ADGRL3, PLEKHA5, SMURF2, UPF2, PLEKHA2, CACYBP, RRAGC, BEX1, TNS1, SPC25, TAF9B, LGR6, APOBEC3G, CENPJ, MCCC2, METTL14, CWC22, SYTL2, TNRC6C, ROBO2, AGO4, CHD8, TRIM39, POLD4, GOPC, MYO10, CD209, SLC40A1, HMG20A, SSU72, VTA1, TNFRSF12A, MYOZ1, PARD6A, ACKR4, EXOSC4, NOP10, NGB, BRD7, MKKS, PNRC2, MED4, CD93, MRPL40, CRTAC1, HEYL, TCF7L2, RTN4, CYLD, HPS4, RRAGD, PFDN4, KMT5A, NECTIN3, EXOSC3, KIF13B, GPHN, NPDC1, PDLIM7, POLE4, EIF2B3, MBNL1, DLL4, ARHGEF4, ARHGEF3, EIF4ENIF1, TSHZ2, SH2B1, POLE3, CHRAC1, PRTFDC1, BAZ1A, LATS2, AASDHPPT, PLSCR4, SMCO4, CDC42SE2, UBQLN4, SNX15, RAB6B, INIP, RASSF1, RPRM, TOMM22, RAD18, HOMER3, PDS5B, RNF146, ACSS1, TMEM106B, UFSP2, TDP1, POT1, NUDT15, EXOC1, NDFIP2, TMEM30A, PARVA, INTS7, FANCI, ARL8B, GNL3L, ASF1B, INTS10, DNAAF2, THAP1, MED9, RNF216, PAG1, PARPBP, PAK1IP1, AURKAIP1, CLN6, NMRK1, GEMIN8, NDUFB11, HYPK, LYAR, SYBU, MKS1, NDE1, CDKN2AIP, GAR1, STAB1, AATF, SPHK1, ABI2, DACT1, BCLAF1, ELOVL5, MIS18A, UGGT1, CDK12, PLK2, ERAP1, PRR13, CLIC5, DTL, ZNF224, MAT2B, EHD3, FLRT3, SEPN1, MPP6, CWC15, MRPL15, CRIPT, NDUFAF4, HACD3, NDUFA13, VAPA, AKAP7, SH3BP4, HMG20B, SPATA7, ZBTB4, STIM2, SLAIN2, FNIP2, BCCIP, ARMCX1, CTTNBP2NL, CHD7, CPSF2, RCOR3, KLHL42, ANKFY1, RERE, SUCLA2, WRAP73, DPM3, ATXN10, NFKBIL1, DNMT3B, SPRR3, ORC3, CLCF1, SAE1, NLK, PI4KB, MYOT, PPARGC1A, UXT, ASH2L, HDAC6, SPAST, VPS29, EIF3K, CTSZ, DNAJB9, RNF14, CTNNAL1, MORF4L1, NXF1, SEL1L, SLC25A10, TJP2, DNAJB4, VTI1B, LRWD1, ZRANB1, TES, KDM5B, DMBT1, PARP2, LIMD1, SEC63, ZC3H7B, KLHL3, SUN2, LAMTOR3, AFF4, MLH3, MKRN1, CHORDC1, TBK1, TRPS1, DCDC2, SLC7A8, DDX20, NUFIP1, USP25, SAP30BP, LGALS13, PUF60, EVL, EIF2B4, ATP6V1H, DACH1, DNAI1, ZNF639, MUTYH, BAZ1B, KLF15, DUSP13, AK3, SCOC, CNOT7, TSPYL4, GGT7, RABGEF1, ANXA10, ZMYM5, ERRFI1, TSKS, CDC23, GGA2, GGA1, NAGPA, ZNF580, LSM7, FEM1B, FBXO10, FBXO9, FBXL2, TNIK, PITPNC1, PILRB, PILRA, NXT1, NUDT5, GTF3C4, ADAMTS7, FBXO5, AMFR, AGO2, VAV3, MYH2, NUP50, ZHX1, INTS6, BAG5, RAB21, RAB22A, PNMA2, BLOC1S6, NRXN1, RAB23, CCPG1, ASAP1, MKL2, ANKRD50, YEATS2, CNOT6, MYO5B, FZD4, CORO1C, PYCARD, PADI4, FZR1, HPCAL4, MYO6, COL17A1, NFU1, PRPF19, SYNPO2, SUFU, BOK, SNX12, G3BP2, POLI, STUB1, MAGED2, CDC14A, SNX6, FAF1, PPIE, TIMELESS, TTF2, TFR2, MACF1, PPP6R1, TNRC6B, SMG5, EXOC7, USP22, TBC1D2B, TRAK1, DICER1, MAPRE3, PA2G4, EXO1, SMC3, MAPK8IP1, HDAC5, ZNF148, HHLA3, TRPC6, NIP7, RUVBL2, CDYL, AKT3, GINS2, LZTS1, HPSE, RNF6, POLH, PRELID1, RUVBL1, TNFSF13B, BCS1L, INVS, FARSA, ITM2B, ASF1A, DRG1, BTRC, CNPY2, SSX2IP, ATP11B, DLGAP4, STK38L, NISCH, PIKFYVE, EPB41L3, SIK3, USP20, FAN1, LAMTOR2, COA3, PTPN22, POLR1D, AP3M1, LEMD3, CARHSP1, THRAP3, GIT1, UBE2D4, SUGT1, LSM2, SH3GLB1, CAB39, LUC7L2, SBDS, CCDC53, FAM96B, PAM16, BOLA1, RABGAP1, TSC22D4, NOC2L, KNSTRN, L3MBTL1, ZNF175, TLN1, KIF3A, TRRAP, TCAF1, DAAM1, PLXND1, USP15, FAM65B, GPSM3, DTNA, LOXL2, MAP4K5, WIPI2, AMMECR1, ARIH1, LSM5, LSM4, SAMM50, CSDC2, HSPB11, CEP83, NUB1, YTHDF2, NME7, PCDHB14, HEY1, UCHL5, ATP6V1D, TNPO3, N6AMT1, GMPPB, MAFB, RBM8A, WIF1, SNX9, SNX5, HEBP2, FHOD1, NCOR2, F11R, SPIN1, FKBP7, TACC3, EID1, ARFGEF2, MAD1L1, STK24, COMMD10, SNCAIP, TEX264, IGF2BP2, SLC30A1, SESN1, TNFRSF11A, NCOA3, SLC4A4, MAP3K4, WASF2, LOC93622

GO:0005516

MF

calmodulin binding

Interacting selectively and non-covalently with calmodulin, a calcium-binding protein with many roles, both in the calcium-bound and calcium-free states.

MYO1G, MYO1C, CASK, ADCY3, EDF1, MYO1D, PCNT, EGFR, MAP2, GAP43, DDX5, ATP2B1, SYT1, ATP2B4, ITPKA, NOS3, MARCKS, MIP, CTH, USP6, MYH9, MYH11, RGS2, PHKA2, PHKA1, IQGAP1, MAPKAPK2, PCYT1A, RGS4, CNN1, DAPK1, GEM, RRAD, VAMP2, SPTBN1, EWSR1, CALD1, TJP1, PPP3CA, CAMSAP2, MYO1E, STRN3, SNTA1, SNTB2, MYO9B, CAMK2D, IQGAP2, SNTB1, CACNA1C, CAMK1, EEA1, RYR3, CNN3, MYLK, UBR4, CAMSAP1, PNCK, IQGAP3, CAMK1D, AEBP1, ASPM, TRPV1, ENKUR, TRPM4, TTN, RYR2, RIT1, MKNK1, IQCG, TRPV6, TRPV4, MKNK2, MYO10, PLCB1, STRN4, SPHK1, NDUFAF4, CAMSAP3, ARPP21, ADD3, FBXL2, MYH2, MYO5B, MYO6, INVS, MYO5A, MYH4

GO:0005518

MF

collagen binding

Interacting selectively and non-covalently with collagen, a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%).

SMAD7, COCH, ITGA10, PDGFB, FN1, VTN, PDGFA, VWF, DCN, CTSL, CTSB, SPARC, SRGN, NID1, MMP9, CD44, ITGA2, PPIB, CTSS, COL5A3, ITGA3, CTSK, COMP, SERPINH1, LUM, SMAD3, COL14A1, DDR1, ADAM9, SMAD4, ITGA9, NID2, SPARCL1, PCOLCE, TGFBI, HSD17B12, CCBE1, PODN, GPR126, C1QTNF1, DSPP, ITGA11, PCOLCE2, ADGRG1

GO:0005519

MF

cytoskeletal regulatory protein binding

Interacting selectively and non-covalently with any protein involved in modulating the reorganization of the cytoskeleton.

CDC42EP3

GO:0005520

MF

insulin-like growth factor binding

Interacting selectively and non-covalently with an insulin-like growth factor, any member of a group of polypeptides that are structurally homologous to insulin and share many of its biological activities, but are immunologically distinct from it.

CYR61, WISP2, WISP1, IGF1R, IGFBP1, IGFBP3, CTGF, HTRA3, IGFBP7, HTRA1, KAZALD1, ESM1, CRIM1

GO:0005521

MF

lamin binding

Interacting selectively and non-covalently with lamin; any of a group of intermediate-filament proteins that form the fibrous matrix on the inner surface of the nuclear envelope.

BNIP3L, PRNP, PPP1CC, IFI27, TMPO, TMPO, PLCB1, SUN2

GO:0005522

MF

profilin binding

Interacting selectively and non-covalently with profilin, an actin-binding protein that forms a complex with G-actin and prevents it from polymerizing to form F-actin.

RHOQ, HTT, CTTN, DBN1, EVL, PCLO

GO:0005523

MF

tropomyosin binding

Interacting selectively and non-covalently with tropomyosin, a protein associated with actin filaments both in cytoplasm and, in association with troponin, in the thin filament of striated muscle.

NEBL, S100A6, TNNT1, TMOD1, LMOD1, CALD1, PYCARD

GO:0005524

MF

ATP binding

Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.

UBA6, UBE2QL1, VWA8, SMCHD1, MYO1G, TK2, DDX39A, MYO1C, CDC7, PIK3CD, RTCA, PIK3C2A, PLK4, DDX3X, NME4, UBE2C, ACACB, PDXK, CHD1, CHD2, TOR1A, ABCD4, RIOK3, MAP2K7, CHEK1, OPLAH, CASK, AURKA, SLC27A2, BTAF1, PIP5K1B, MAST4, PFAS, DCLK1, MUSK, MAPK13, ABCC4, ABCC5, DHX15, IRAK2, DYNC1LI2, MAP3K13, DAPK3, MAP3K7, RIPK2, RAD51C, ATP8B1, ASNA1, BUB1, GATC, KIF1C, ORC5, DHX16, SMARCA5, ADCY3, KIF5C, NUAK1, PIP5K1C, KIF1B, ACSL4, ADCY9, BUB1B, JAK2, PFKFB2, DNAJA2, FAM20B, ATP9A, ROCK2, VPS4B, ENTPD3, ULK1, NME6, POLQ, ERN1, RPS6KA5, TRMU, RAD51D, GATB, PAK3, CLPX, SLC22A5, RECQL4, STK17B, MYO1D, ABCA8, RHOBTB3, FSBP, UBE4B, KIF20A, KIF4A, PAPSS2, SMC2, FARS2, ABCA1, MAP4K4, LATS1, TTLL1, EGFR, PGK1, AK1, ASS1, RAF1, TK1, ERBB2, NTRK1, TP53, ATP1B1, PCCA, PRKCB, INSR, FYN, CDK1, CSF1R, EPRS, HSP90AA1, LYN, IGF1R, HSP90AB1, ASNS, MET, PDGFRB, FGR, HSPA1A, HSPA1B, KIT, HSPD1, HSPA5, BCR, FGFR1, TOP2A, PC, MTHFD1, PSKH1, CDK4, PRPS2, HARS, CKB, CKMT1A, XRCC5, CFTR, GTF2F2, PKM, HSP90B1, IDE, DARS, NME1, PFKFB1, PDGFRA, ATP2A2, HSPA6, PRKCA, CKMT2, SYN1, PRKACA, CTPS1, DDX5, PFKL, PSMC3, TCP1, ERCC2, LIG1, HK1, ATP2B1, MSH3, NPR2, MAK, CDK11B, ATP6V1B2, FGFR2, ERBB3, GART, PAICS, UBA1, NME2, ENPP1, JAK1, ATP2B4, ITPKA, DTYMK, RRM1, CDK2, MCM3, TARS, ACVR2A, AK4, MAPK3, DCK, CAD, ABCD3, SMARCA1, MAPK1, EPHA3, EPHB2, LTK, ATP5D, CMPK1, PEBP1, WEE1, MAT2A, DNAJA1, AKT1, AKT2, GK, ACSL1, ABCC1, TTK, MCM4, MCM5, MCM7, HSPA1L, HSPA4, GRK5, RFC4, RFC2, MYH9, TIE1, ADRBK2, MYH11, CHKA, FLT4, PSMC2, MAP2K2, BMPR1A, ACVR1B, TGFBR1, TGFBR2, CCT6A, MLH1, RFC5, UBA7, CSK, MAP3K8, PRKCI, ACTR1B, SKIV2L2, PIK3CA, PIK3CB, ABL2, HELZ, MSH2, GRK6, SYK, PSMC4, MAPK8, MAPK9, MKI67, RECQL, ATRX, NSF, GCLC, CSNK1A1, CSNK1D, PIK3CG, MAPKAPK2, CDK8, CCT3, CDC34, UBE2A, HARS2, SARS, CSNK1E, MCM2, CLK2, GSK3B, SEPHS1, MTHFS, GMPS, CDK7, CCT8, ATP1A2, PAPOLA, DNA2, SMARCA2, SMARCA4, IRAK1, CLCN3, CLCN4, CLCN5, CLCN6, CLCN7, PRKX, ADCY7, NEK2, NEK3, NEK4, UBE2E1, JAK3, MAP2K6, MSH6, KIF11, PLK1, DAPK1, MVD, LIMK2, BLM, RARS, PMS1, YARS, PRKAG1, PRKAA2, ATP12A, EPHA5, EPHB4, EPHB1, EPHA4, ALDH18A1, VCP, SIK1, NLRP5, ACTB, EIF4A1, PRPS1, UBE2D3, UBE2M, ACTR3, ACTR2, ABCE1, HSPE1, PSMC1, UBE2H, PSMC6, ACTA2, UBE2B, ACTG1, ACTG2, UBE2I, ACTC1, PIP4K2B, SRPK2, CCT2, PRKDC, ATP2C1, CDK3, CDK6, CDK5, CDK16, HNRNPU, RUNX1, GALK2, ROR1, CENPE, KIF23, MAP2K1, TEK, FKBP4, GUCY2D, MVK, PRKCQ, ACVR1, PTK2, PRKCD, RNASEL, TYRO3, RAD51, TNK2, DDR1, SLFN5, DMPK, DNAH14, HSPA14, TWF1, MERTK, ILF2, MYO1E, STK4, COASY, MAP2K5, MAPK7, PAK2, G3BP1, PTK7, ORC1, ILK, MYO9B, PRPF4B, RIPK1, CAMK2D, ITPK1, DGKZ, ACVR2B, RUNX3, BMPR2, RUNX2, CDK13, CAMK1, DYNC1H1, EIF4A2, FASTK, MCM6, KCNJ11, MELK, SMC1A, KIF22, CHD4, SHPRH, LARS2, KARS, KIF14, PDK1, CDK10, PRKD1, STK38, PPP2R4, ERBB4, RPS6KA2, RPS6KA1, TESK1, TRIP13, MYLK, STK11, PKN1, PKN2, MAPK14, NTRK2, PDK4, AMHR2, UBE2S, GUK1, DGUOK, PFKFB3, PFKFB4, AAK1, ERCC6L, HKDC1, PGS1, CHD9, TKFC, TTLL9, NADK2, AASDH, ATP13A5, SBK1, ACSM3, PAN3, CMPK2, DDX60L, EARS2, TOR2A, DGKK, ABCC10, IDNK, ERCC6L2, ATAD3B, MLK4, CDC42BPA, NADSYN1, TWF2, STYK1, MAST2, PNCK, PPIP5K1, PAPD4, ATAD2, MTHFD1L, DSTYK, AATK, DNAH12, GK5, BBS12, NEK10, DDX46, DHX30, PARS2, DHX32, NRK, SETX, DHX29, NEK8, STK32C, AACS, LONP2, NLRC5, CHD1L, DGKH, KIF18B, SGK223, CAMK1D, DNAH10, MAP4K3, NAV2, CARKD, TEX14, DHX40, FAM20C, SMC5, DHX37, SUPV3L1, FANCM, SCYL3, ABCA6, TOR2A, UBE2J2, ASCC3, MINK1, ATAD1, TDRD9, STKLD1, ABCF1, PIK3C3, TRPV1, ANKK1, FBXO18, NEK11, TTL, KIF18A, BBS10, UHMK1, NUBPL, NEK9, TRPM4, DDX54, HELQ, STK35, NEK7, DNAH5, ATP8B4, GSG2, CHTF18, DCAKD, DNAJA4, ABCA5, TTN, HSPH1, KIAA0232, DYRK2, RAD54L, SYN2, DDX17, RAD50, RFK, UBE2E3, UBE2W, SGK3, ULK4, DNAH11, KTI12, MMAB, AURKB, DDX27, MASTL, MYO19, PBK, SCYL1, MARK4, UBE2E2, AK8, NEK1, TRNT1, SMG1, KIF20B, ALPK1, TRPM7, MAGI1, PASK, MCCC1, PEO1, TRIB3, TP53RK, SRPK1, SMC6, NMNAT3, YME1L1, PIK3R4, P2RX4, PKMYT1, KIF2C, MAP3K5, CDC6, CCT7, TEP1, VRK1, MKNK1, DDX23, FICD, KIFC1, KATNAL1, PAPOLG, CDK19, TRPM6, PINK1, HELZ2, WNK3, PANK2, PRKD2, UCK2, STRADB, DDX24, UBA5, SIK2, QRSL1, DDX47, ABCG8, EHD4, TAOK3, DHX36, HIPK2, TPK1, TOR3A, WNK1, SMARCAD1, DHX35, PIF1, ACSS3, YTHDC2, ATP13A3, UBE2Z, DDX31, CNNM2, PANK3, UCK1, CLK4, TRPV4, MKNK2, ETNK1, NEK6, MCCC2, CHD8, CSNK1G1, MYO10, ABCB6, PNPLA8, UBE2T, MKKS, ATP13A2, KIF13B, GPHN, ACSS2, CTPS2, ABCB10, LATS2, HELLS, KIF15, NRBP2, BMP2K, PDS5B, SMC4, MDN1, ACSS1, DDX28, ATAD3A, MTPAP, NMRK1, UCKL1, DDX43, SPHK1, DNAH9, ZAK, CDK12, PLK2, EHD3, NDUFA13, MARK1, PAK7, CHD7, DNAH1, EIF2AK4, STARD9, SUCLA2, NLK, PI4KB, SPAST, EPHA6, ABCF2, PRKAG3, MLH3, CHORDC1, TBK1, IP6K2, DDX20, SHPK, BAZ1B, AK3, MCM8, TNIK, TLK1, ACSL6, MYH2, TAOK2, RIMKLB, MYO5B, TPX2, MYO6, TTF2, DICER1, CDK11A, SMC3, GNE, RUVBL2, AKT3, CHKB, RUVBL1, BCS1L, FARSA, ITM2B, ATP11B, STK38L, PIKFYVE, SIK3, DDX52, THRAP3, UBE2D4, RTCB, KIF3A, MYO5A, MAP4K5, HYOU1, NME7, CDC42BPB, IRAK3, RAD54B, MYH4, STK24, CSNK1G3, MAP3K4, DDX49

GO:0005525

MF

GTP binding

Interacting selectively and non-covalently with GTP, guanosine triphosphate.

GTPBP10, RAB27B, RHOD, RAB29, OPA1, EIF5B, RP2, MFN2, DIRAS3, NRAS, KRAS, TUBB4A, GNAI2, SCG5, INSR, TUBB, HSP90AA1, ANXA6, HSP90AB1, GNAI3, RAP2A, RRAS, RALA, RALB, EEF2, RAC2, GSPT1, NME1, RHOQ, ARF4, RAB3B, RAB5A, NPR2, TGM2, TUBG1, AK4, GNA11, ADSS, GBP1, GBP2, PCK1, TRIM23, GNL1, EIF2S3, GLUD2, ARL4D, SEPHS1, GNAQ, RAB5C, RAB7A, RAB9A, RAB28, RAB27A, DAPK1, SUCLG1, EIF5, GEM, RRAD, RAC3, CDC42, SRP54, RAB4B, RAB2A, RAB5B, RAP2B, RHOA, RRAS2, RAB11A, RHOB, RAB1A, RAP1A, RAC1, GNAI1, EEF1A1, TUBA1B, TUBA4A, TUBB4B, ARF1, ARF5, GNAS, FKBP4, GUCY2D, GNA12, EEF1A2, ARL16, ARHGEF5, RAB40B, ARHGAP5, TUBB3, RAB31, RAB32, TUBA3C, TUBB2A, RAB33A, SEPT6, SEPT2, RHEB, RAB11B, SEPT7, PCK2, TSR1, RABL6, IFI44L, GNAS, ATL3, RAB12, GBP6, TUBA1A, RHOU, MMAA, ARL17A, RASEF, ADSSL1, GTPBP8, GUF1, NIN, ARL14, ATL2, RHEBL1, URGCP, RAB2B, RAB8B, RIT1, GTPBP3, RERG, ARL8A, UPRT, RASD2, RAB39B, NUDT16, ARL5B, GFM1, RASL10B, RASL11B, MTG1, TUBB6, TUBB2B, GNL3, IFT27, RAB34, GBP3, RAB1B, EHD4, TUBB1, RHOJ, MTG2, RRAGC, RRAGD, RAB6B, ARL8B, GNL3L, NKIRAS1, EHD3, DNAJC27, AK3, TUBE1, TUBD1, RAB21, RAB22A, RAB23, TPX2, AGAP1, RASD1, DRG1, HBS1L, MFHAS1, SRPRB, GMPPB, ARL5A, SAR1B

GO:0005528

MF

FK506 binding

Interacting selectively and non-covalently with the 23-membered macrolide lactone FK506.

NFATC1, FKBP2, FKBP3, FKBP4, FKBP5, FKBP10, FKBP14, FKBP11, FKBP7

GO:0005534

MF

galactose binding

Interacting selectively and non-covalently with the aldohexose galactose (galacto-hexose), a common constituent of many oligo- and polysaccharides.

COLEC12

GO:0005536

MF

glucose binding

Interacting selectively and non-covalently with the D- or L-enantiomer of glucose.

SLC2A3, G6PD, GYS1, HK1, UGP2, HKDC1

GO:0005537

MF

mannose binding

Interacting selectively and non-covalently with mannose, a monosaccharide hexose, stereoisomeric with glucose, that occurs naturally only in polymerized forms called mannans.

CLN5, MBL2, IGF2R, MRC1, BSG, LMAN2L, CD209

GO:0005539

MF

glycosaminoglycan binding

Interacting selectively and non-covalently with any glycan (polysaccharide) containing a substantial proportion of aminomonosaccharide residues.

SERPINA5, SERPINE2, DCN, VCAN, BGN, TGFBR2, TGFBR3, NDNF, SPOCK2, EPYC, SPOCK3

GO:0005540

MF

hyaluronic acid binding

Interacting selectively and non-covalently with hyaluronic acid, a polymer composed of repeating dimeric units of glucuronic acid and N-acetyl glucosamine.

NCAN, HMMR, HAPLN1, VCAN, CD44, TNFAIP6, C1QBP, HYAL2, CEMIP, STAB2, BCAN, STAB1, LYVE1

GO:0005542

MF

folic acid binding

Interacting selectively and non-covalently with folic acid, pteroylglutamic acid. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines.

DHFR, TYMS, FOLR1, SLC19A1, MTHFS, SLC46A1

GO:0005543

MF

phospholipid binding

Interacting selectively and non-covalently with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester.

NR5A2, SEC14L2, ABCA1, GOT2, APOA1, APOE, APOA2, APOC3, APOH, ANXA1, APOB, ANXA5, PLA2G2A, PTAFR, PON1, GRK5, NUP62, SNCA, PRKCI, VAMP2, SPTBN1, PLA2G7, APOA5, NBEAL1, NUP35, NSMAF, BAD, SYTL4, OSBPL1A, PACSIN1, NUP62CL, SPTBN4, MAP1LC3A, BIN2, ARHGAP26, NSFL1C, PLA2G4C, AGAP1

GO:0005544

MF

calcium-dependent phospholipid binding

Interacting selectively and non-covalently with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester, in the presence of calcium.

ESYT2, ANXA1, ANXA2, ANXA6, ANXA5, ANXA4, ANXA3, SYT1, PLA2G4A, ANXA11, C2CD5, SYTL5, SYTL4, SYTL2, ANXA10, PCLO