Search Geneontologies

Geneontologies

GO ID Ontology GO Term Term Definition Proteins

GO:2001033

BP

negative regulation of double-strand break repair via nonhomologous end joining

Any process that stops, prevents or reduces the frequency, rate or extent of double-strand break repair via nonhomologous end joining.

HMGA2

GO:2001034

BP

positive regulation of double-strand break repair via nonhomologous end joining

Any process that activates or increases the frequency, rate or extent of double-strand break repair via nonhomologous end joining.

RIF1

GO:2001037

BP

positive regulation of tongue muscle cell differentiation

Any process that activates or increases the frequency, rate or extent of tongue muscle cell differentiation.

TBX1, CYP26B1

GO:2001038

BP

regulation of cellular response to drug

Any process that modulates the frequency, rate or extent of cellular response to drug.

HMGA2, NCOA1

GO:2001044

BP

regulation of integrin-mediated signaling pathway

Any process that modulates the frequency, rate or extent of integrin-mediated signaling pathway.

ITGB1BP1, TIMP1, PRKD1

GO:2001045

BP

negative regulation of integrin-mediated signaling pathway

Any process that stops, prevents or reduces the frequency, rate or extent of integrin-mediated signaling pathway.

CTNNA1, PHACTR4

GO:2001046

BP

positive regulation of integrin-mediated signaling pathway

Any process that activates or increases the frequency, rate or extent of integrin-mediated signaling pathway.

FLNA, EMP2

GO:2001054

BP

negative regulation of mesenchymal cell apoptotic process

Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell apoptotic process.

TBX1, GDF5, SOX9, HIF1A

GO:2001056

BP

positive regulation of cysteine-type endopeptidase activity

Any process that activates or increases the frequency, rate or extent of cysteine-type endopeptidase activity.

PYCARD

GO:2001076

BP

positive regulation of metanephric ureteric bud development

Any process that activates or increases the frequency, rate or extent of metanephric ureteric bud development.

WT1

GO:2001106

BP

regulation of Rho guanyl-nucleotide exchange factor activity

Any process that modulates the frequency, rate or extent of Rho guanyl-nucleotide exchange factor activity.

CCPG1

GO:2001108

BP

positive regulation of Rho guanyl-nucleotide exchange factor activity

Any process that activates or increases the frequency, rate or extent of Rho guanyl-nucleotide exchange factor activity.

EPHA4

GO:2001113

BP

negative regulation of cellular response to hepatocyte growth factor stimulus

Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to hepatocyte growth factor stimulus.

ADAMTS12

GO:2001135

BP

regulation of endocytic recycling

Any process that modulates the frequency, rate or extent of endocytic recycling.

RAB11B, BVES, NDRG4

GO:2001137

BP

positive regulation of endocytic recycling

Any process that activates or increases the frequency, rate or extent of endocytic recycling.

ACTN2, SORL1

GO:2001140

BP

positive regulation of phospholipid transport

Any process that activates or increases the frequency, rate or extent of phospholipid transport.

TRIAP1, PRELID1

GO:2001141

BP

regulation of RNA biosynthetic process

Any process that modulates the frequency, rate or extent of RNA biosynthetic process.

MITF, NCOA3

GO:2001150

BP

positive regulation of dipeptide transmembrane transport

Any process that activates or increases the frequency, rate or extent of dipeptide transmembrane transport.

CA2

GO:2001153

BP

positive regulation of renal water transport

Any process that activates or increases the frequency, rate or extent of renal water transport.

INPP5K

GO:2001170

BP

negative regulation of ATP biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of ATP biosynthetic process.

PID1, FLCN

GO:2001171

BP

positive regulation of ATP biosynthetic process

Any process that activates or increases the frequency, rate or extent of ATP biosynthetic process.

STAT3, VCP, PID1, PINK1, PPARGC1A

GO:2001180

BP

negative regulation of interleukin-10 secretion

Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-10 secretion.

TNFRSF21, LILRB1

GO:2001181

BP

positive regulation of interleukin-10 secretion

Any process that activates or increases the frequency, rate or extent of interleukin-10 secretion.

PYCARD

GO:2001182

BP

regulation of interleukin-12 secretion

Any process that modulates the frequency, rate or extent of interleukin-12 secretion.

FOXP1

GO:2001183

BP

negative regulation of interleukin-12 secretion

Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-12 secretion.

LILRB1

GO:2001184

BP

positive regulation of interleukin-12 secretion

Any process that activates or increases the frequency, rate or extent of interleukin-12 secretion.

MAPK14

GO:2001186

BP

negative regulation of CD8-positive, alpha-beta T cell activation

Any process that stops, prevents or reduces the frequency, rate or extent of CD8-positive, alpha-beta T cell activation.

HFE, LILRB1

GO:2001189

BP

negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell

Any process that stops, prevents or reduces the frequency, rate or extent of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell.

LGALS3, LILRB1

GO:2001190

BP

positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell

Any process that activates or increases the frequency, rate or extent of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell.

HLA-DMB

GO:2001193

BP

positive regulation of gamma-delta T cell activation involved in immune response

Any process that activates or increases the frequency, rate or extent of gamma-delta T cell activation involved in immune response.

LILRB1

GO:2001199

BP

negative regulation of dendritic cell differentiation

Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell differentiation.

HLA-G, TMEM176B, LILRB1, TMEM176A

GO:2001200

BP

positive regulation of dendritic cell differentiation

Any process that activates or increases the frequency, rate or extent of dendritic cell differentiation.

HMGB1

GO:2001202

BP

negative regulation of transforming growth factor-beta secretion

Any process that stops, prevents or reduces the frequency, rate or extent of transforming growth factor-beta secretion.

FN1, LILRB1

GO:2001204

BP

regulation of osteoclast development

Any process that modulates the frequency, rate or extent of osteoclast development.

TYROBP

GO:2001205

BP

negative regulation of osteoclast development

Any process that stops, prevents or reduces the frequency, rate or extent of osteoclast development.

FBN1, LILRB1

GO:2001206

BP

positive regulation of osteoclast development

Any process that activates or increases the frequency, rate or extent of osteoclast development.

TNFSF11

GO:2001212

BP

regulation of vasculogenesis

Any process that modulates the frequency, rate or extent of vasculogenesis.

EMP2, HEY1

GO:2001213

BP

negative regulation of vasculogenesis

Any process that stops, prevents or reduces the frequency, rate or extent of vasculogenesis.

XDH

GO:2001214

BP

positive regulation of vasculogenesis

Any process that activates or increases the frequency, rate or extent of vasculogenesis.

ADM, RAP1A

GO:2001222

BP

regulation of neuron migration

Any process that modulates the frequency, rate or extent of neuron migration.

PLXNB2, FLRT2, ULK4, ZSWIM6

GO:2001223

BP

negative regulation of neuron migration

Any process that stops, prevents or reduces the frequency, rate or extent of neuron migration.

GNRH1, COL3A1, STAT3, NRG1, ERBB4, ADGRG1

GO:2001224

BP

positive regulation of neuron migration

Any process that activates or increases the frequency, rate or extent of neuron migration.

SEMA3A, NSMF, KIF20B, SEMA6A

GO:2001225

BP

regulation of chloride transport

Any process that modulates the frequency, rate or extent of chloride transport.

CA2

GO:2001229

BP

negative regulation of response to gamma radiation

Any process that stops, prevents or reduces the frequency, rate or extent of response to gamma radiation.

PRKDC

GO:2001234

BP

negative regulation of apoptotic signaling pathway

Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic signaling pathway.

BCL2, CTH, CTNNB1, NR4A2, PSEN1, IGBP1, BAX, MNT, MEIS3

GO:2001235

BP

positive regulation of apoptotic signaling pathway

Any process that activates or increases the frequency, rate or extent of apoptotic signaling pathway.

INHBB, CTSH, TGFBR1, MAPK9, CTSC, CRADD, PRKCD, NFATC4, TPD52L1, TP53INP1, TRIM39

GO:2001236

BP

regulation of extrinsic apoptotic signaling pathway

Any process that modulates the frequency, rate or extent of extrinsic apoptotic signaling pathway.

TRAF1, DEPTOR

GO:2001237

BP

negative regulation of extrinsic apoptotic signaling pathway

Any process that stops, prevents or reduces the frequency, rate or extent of extrinsic apoptotic signaling pathway.

NRP1, CFLAR, SIAH2, NOL3, LMNA, IGF1, ITGAV, THBS1, GSTP1, AR, BMP4, SCG2, LGALS3, ITGA6, TGFBR1, HTT, YAP1, GCLC, GCLM, PSME3, RELA, ACVR1, RIPK1, CTTN, ZMYND11, RB1CC1, PHIP, TCF7L2, PAK7

GO:2001238

BP

positive regulation of extrinsic apoptotic signaling pathway

Any process that activates or increases the frequency, rate or extent of extrinsic apoptotic signaling pathway.

BCL10, AGT, G0S2, PDIA3, LTBR, AGTR2, TNFSF10, BID, CAV1, HYAL2, FADD, PAK2, RIPK1, GPER1, TNFRSF12A, CYLD, PYCARD

GO:2001239

BP

regulation of extrinsic apoptotic signaling pathway in absence of ligand

Any process that modulates the frequency, rate or extent of extrinsic apoptotic signaling pathway in absence of ligand.

FGFR1

GO:2001240

BP

negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Any process that stops, prevents or reduces the frequency, rate or extent of extrinsic apoptotic signaling pathway in absence of ligand.

EYA2, SNAI2, EYA4, TNF, IL1A, IL1B, PF4, FYN, HSPA1A, HSPA1B, BCL2, AKT1, CTNNA1, MCL1, MAP2K5, MAPK7, RIPK1, UNC5B, STRADB

GO:2001241

BP

positive regulation of extrinsic apoptotic signaling pathway in absence of ligand

Any process that activates or increases the frequency, rate or extent of extrinsic apoptotic signaling pathway in absence of ligand.

DAPK3, INHBA, FAS, PPP2R1A, PPP2R1B, CTNNA1, TGFB2, PPP1CA, BAX

GO:2001242

BP

regulation of intrinsic apoptotic signaling pathway

Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway.

CYLD, PYCARD

GO:2001243

BP

negative regulation of intrinsic apoptotic signaling pathway

Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway.

DDX3X, URI1, GCG, BCL2, MMP9, PPIF, VDAC2, PLAUR, MCL1, BCL2L2, NDUFA13, MAPK8IP1, NOC2L, IVNS1ABP

GO:2001244

BP

positive regulation of intrinsic apoptotic signaling pathway

Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway.

BCL2L11, PRKRA, TP53, S100A8, S100A9, BCL2, BCAP31, BID, RACK1, CAV1, BAX, PMAIP1, SIAH1, FLCN, BAD, BCLAF1

GO:2001250

BP

positive regulation of ammonia assimilation cycle

Any process that activates or increases the frequency, rate or extent of ammonia assimilation cycle.

NR1H4

GO:2001256

BP

regulation of store-operated calcium entry

Any process that modulates the frequency, rate or extent of store-operated calcium entry.

STC2, SPINK1, HOMER1

GO:2001257

BP

regulation of cation channel activity

Any process that modulates the frequency, rate or extent of cation channel activity.

HOMER1, KCNIP2

GO:2001258

BP

negative regulation of cation channel activity

Any process that stops, prevents or reduces the frequency, rate or extent of cation channel activity.

MMP9, FGF12

GO:2001259

BP

positive regulation of cation channel activity

Any process that activates or increases the frequency, rate or extent of cation channel activity.

CTSS, ACTN2, ANK2, ANK3, KCNJ11

GO:2001268

BP

negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

Any process that stops, prevents or reduces the frequency, rate or extent of cysteine-type endopeptidase activity involved in apoptotic signaling pathway.

MMP9, PLAUR

GO:2001271

BP

negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis

Any process that stops, prevents or reduces the frequency, rate or extent of cysteine-type endopeptidase activity involved in execution phase of apoptosis.

PAK2, RFFL

GO:2001273

BP

regulation of glucose import in response to insulin stimulus

Any process that modulates the frequency, rate or extent of glucose import in response to insulin stimulus.

NGFR, REPIN1

GO:2001274

BP

negative regulation of glucose import in response to insulin stimulus

Any process that stops, prevents or reduces the frequency, rate or extent of glucose import in response to insulin stimulus.

PID1

GO:2001275

BP

positive regulation of glucose import in response to insulin stimulus

Any process that activates or increases the frequency, rate or extent of glucose import in response to insulin stimulus.

AGT, PIK3R1, AKT2, IRS1, RNASEL, PTPN11, C2CD5, NR1H4, RARRES2, OSBPL8

GO:2001287

BP

negative regulation of caveolin-mediated endocytosis

Any process that stops, prevents or reduces the frequency, rate or extent of caveolin-mediated endocytosis.

UNC119

GO:2001288

BP

positive regulation of caveolin-mediated endocytosis

Any process that activates or increases the frequency, rate or extent of caveolin-mediated endocytosis.

NEDD4L

GO:2001295

BP

malonyl-CoA biosynthetic process

The chemical reactions and pathways resulting in the formation of malonyl-CoA, the S-malonyl derivative of coenzyme A.

ACACB

GO:2001300

BP

lipoxin metabolic process

The chemical reactions and pathways involving a lipoxin. A lipoxin is a non-classic eicosanoid and signalling molecule that has four conjugated double bonds and is derived from arachidonic acid.

ALOX5, HPGD

GO:2001303

BP

lipoxin A4 biosynthetic process

The chemical reactions and pathways resulting in the formation of lipoxin A4. Lipoxin A4 is a C20 hydroxy fatty acid having (5S)-, (6R)- and (15S)-hydroxy groups as well as (7E)- (9E)-, (11Z)- and (13E)-double bonds.

ALOX15

GO:2001311

BP

lysobisphosphatidic acid metabolic process

The chemical reactions and pathways involving a lysobisphosphatidic acid. A lysobisphosphatidic acid is a lysophosphatidic acid having the unusual property of a phosphodiester moiety linked to positions sn-1 and sn1' of glycerol; and two additional fatty acids esterified to the glycerol head group.

ACP6

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