| GO ID | Ontology | GO Term | Term Definition |
Proteins |
GO:2000649 | BP | regulation of sodium ion transmembrane transporter activity | Any process that modulates the frequency, rate or extent of sodium ion transmembrane transporter activity. |
FXYD1, FXYD4, FGF12, YWHAH, RANGRF |
GO:2000650 | BP | negative regulation of sodium ion transmembrane transporter activity | Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion transmembrane transporter activity. |
CAMK2D, PCSK9, OSR1, NEDD4L |
GO:2000651 | BP | positive regulation of sodium ion transmembrane transporter activity | Any process that activates or increases the frequency, rate or extent of sodium ion transmembrane transporter activity. |
DMD, GLRX, ANK3, WNK3 |
GO:2000653 | BP | regulation of genetic imprinting | Any process that modulates the frequency, rate or extent of genetic imprinting. |
PIK3CA, TRIM28 |
GO:2000657 | BP | negative regulation of apolipoprotein binding | Any process that stops, prevents or reduces the frequency, rate or extent of apolipoprotein binding. |
MAPK3 |
GO:2000660 | BP | negative regulation of interleukin-1-mediated signaling pathway | Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-1-mediated signaling pathway. |
IL6, IL1RN, IL1R2, ZNF675 |
GO:2000661 | BP | positive regulation of interleukin-1-mediated signaling pathway | Any process that activates or increases the frequency, rate or extent of interleukin-1-mediated signaling pathway. |
IL1R1 |
GO:2000663 | BP | negative regulation of interleukin-5 secretion | Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-5 secretion. |
TNFRSF21 |
GO:2000664 | BP | positive regulation of interleukin-5 secretion | Any process that activates or increases the frequency, rate or extent of interleukin-5 secretion. |
IL17RB |
GO:2000666 | BP | negative regulation of interleukin-13 secretion | Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-13 secretion. |
TNFRSF21 |
GO:2000667 | BP | positive regulation of interleukin-13 secretion | Any process that activates or increases the frequency, rate or extent of interleukin-13 secretion. |
PAEP, IL17RB |
GO:2000669 | BP | negative regulation of dendritic cell apoptotic process | Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell apoptotic process. |
GAS6, LILRB1 |
GO:2000670 | BP | positive regulation of dendritic cell apoptotic process | Any process that activates or increases the frequency, rate or extent of dendritic cell apoptotic process. |
LYN |
GO:2000672 | BP | negative regulation of motor neuron apoptotic process | Any process that stops, prevents or reduces the frequency, rate or extent of motor neuron apoptotic process. |
ZPR1 |
GO:2000675 | BP | negative regulation of type B pancreatic cell apoptotic process | Any process that stops, prevents or reduces the frequency, rate or extent of type B pancreatic cell apoptotic process. |
CAST, SRSF6, TCF7L2 |
GO:2000676 | BP | positive regulation of type B pancreatic cell apoptotic process | Any process that activates or increases the frequency, rate or extent of type B pancreatic cell apoptotic process. |
EIF2S1, IL6, HDAC1, CAPN10 |
GO:2000678 | BP | negative regulation of transcription regulatory region DNA binding | Any process that stops, prevents or reduces the frequency, rate or extent of transcription regulatory region DNA binding. |
SRI, LHX2, PPARA, ZNF675, HEY1 |
GO:2000679 | BP | positive regulation of transcription regulatory region DNA binding | Any process that activates or increases the frequency, rate or extent of transcription regulatory region DNA binding. |
KLF4, TGFB1, IGF1, RB1, PARP1, HMGA2, TWIST1, TRIM6 |
GO:2000681 | BP | negative regulation of rubidium ion transport | Any process that stops, prevents or reduces the frequency, rate or extent of rubidium ion transport. |
CAB39 |
GO:2000682 | BP | positive regulation of rubidium ion transport | Any process that activates or increases the frequency, rate or extent of rubidium ion transport. |
WNK3 |
GO:2000685 | BP | positive regulation of cellular response to X-ray | Any process that activates or increases the frequency, rate or extent of cellular response to X-ray. |
HMGA2 |
GO:2000687 | BP | negative regulation of rubidium ion transmembrane transporter activity | Any process that stops, prevents or reduces the frequency, rate or extent of rubidium ion transmembrane transporter activity. |
CAB39 |
GO:2000688 | BP | positive regulation of rubidium ion transmembrane transporter activity | Any process that activates or increases the frequency, rate or extent of rubidium ion transmembrane transporter activity. |
WNK3 |
GO:2000691 | BP | negative regulation of cardiac muscle cell myoblast differentiation | Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle cell myoblast differentiation. |
PRICKLE1 |
GO:2000696 | BP | regulation of epithelial cell differentiation involved in kidney development | Any process that modulates the frequency, rate or extent of epithelial cell differentiation involved in kidney development. |
PRKX |
GO:2000707 | BP | positive regulation of dense core granule biogenesis | Any process that activates or increases the frequency, rate or extent of dense core granule biogenesis. |
PRKCA |
GO:2000724 | BP | positive regulation of cardiac vascular smooth muscle cell differentiation | Any process that activates or increases the frequency, rate or extent of cardiac vascular smooth muscle cell differentiation. |
GPER1 |
GO:2000726 | BP | negative regulation of cardiac muscle cell differentiation | Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle cell differentiation. |
DKK1, BMP2, SOX6 |
GO:2000727 | BP | positive regulation of cardiac muscle cell differentiation | Any process that activates or increases the frequency, rate or extent of cardiac muscle cell differentiation. |
GREM1, TGFB1, EFNB2, NRG1, MEF2C |
GO:2000736 | BP | regulation of stem cell differentiation | Any process that modulates the frequency, rate or extent of stem cell differentiation. |
TEAD2 |
GO:2000737 | BP | negative regulation of stem cell differentiation | Any process that stops, prevents or reduces the frequency, rate or extent of stem cell differentiation. |
STAT3, NOTCH1, YAP1, ZFP36L2, JAG1, HES1, TRIM6 |
GO:2000738 | BP | positive regulation of stem cell differentiation | Any process that activates or increases the frequency, rate or extent of stem cell differentiation. |
GSK3B, PWP1 |
GO:2000739 | BP | regulation of mesenchymal stem cell differentiation | Any process that modulates the frequency, rate or extent of mesenchymal stem cell differentiation. |
PDGFRA |
GO:2000741 | BP | positive regulation of mesenchymal stem cell differentiation | Any process that activates or increases the frequency, rate or extent of mesenchymal stem cell differentiation. |
SOX6, SOX9, LTBP3 |
GO:2000744 | BP | positive regulation of anterior head development | Any process that activates or increases the frequency, rate or extent of anterior head development. |
SSBP3 |
GO:2000751 | BP | histone H3-T3 phosphorylation involved in chromosome passenger complex localization to kinetochore | Any histone H3-T3 phosphorylation that is involved in chromosome passenger complex localization to kinetochore. |
GSG2 |
GO:2000753 | BP | positive regulation of glucosylceramide catabolic process | Any process that activates or increases the frequency, rate or extent of glucosylceramide catabolic process. |
PRKCD |
GO:2000755 | BP | positive regulation of sphingomyelin catabolic process | Any process that activates or increases the frequency, rate or extent of sphingomyelin catabolic process. |
PRKCD |
GO:2000757 | BP | negative regulation of peptidyl-lysine acetylation | Any process that stops, prevents or reduces the frequency, rate or extent of peptidyl-lysine acetylation. |
HDAC1, HDAC2, KLF15 |
GO:2000761 | BP | positive regulation of N-terminal peptidyl-lysine acetylation | Any process that activates or increases the frequency, rate or extent of N-terminal peptidyl-lysine acetylation. |
SOX4 |
GO:2000766 | BP | negative regulation of cytoplasmic translation | Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translation. |
FMR1, CPEB4, CPEB2, CPEB3, UNK |
GO:2000767 | BP | positive regulation of cytoplasmic translation | Any process that activates or increases the frequency, rate or extent of cytoplasmic translation. |
EEF2 |
GO:2000768 | BP | positive regulation of nephron tubule epithelial cell differentiation | Any process that activates or increases the frequency, rate or extent of nephron tubule epithelial cell differentiation. |
CD24 |
GO:2000772 | BP | regulation of cellular senescence | Any process that modulates the frequency, rate or extent of cellular senescence. |
ARNTL, NUAK1, RSL1D1, BMPR1A, NEK4, PNPT1, NEK6, ZNF277 |
GO:2000773 | BP | negative regulation of cellular senescence | Any process that stops, prevents or reduces the frequency, rate or extent of cellular senescence. |
BCL6, PRKDC, CDK6, TWIST1, BCL2L12 |
GO:2000774 | BP | positive regulation of cellular senescence | Any process that activates or increases the frequency, rate or extent of cellular senescence. |
EEF1E1, KRAS, HMGA1, HMGA2, YPEL3, PAWR |
GO:2000775 | BP | histone H3-S10 phosphorylation involved in chromosome condensation | Any histone H3-S10 phosphorylation that is involved in chromosome condensation. |
CCNB1 |
GO:2000777 | BP | positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia | Any positive regulation of proteasomal ubiquitin-dependent protein catabolic process that is involved in a cellular response to hypoxia. |
SIRT2 |
GO:2000778 | BP | positive regulation of interleukin-6 secretion | Any process that activates or increases the frequency, rate or extent of interleukin-6 secretion. |
IL1B, HMGB1, PAEP, HSPD1, XBP1, F2R, F2RL1, HYAL2, TWIST1, TRPV4, IL1RAP, PYCARD |
GO:2000779 | BP | regulation of double-strand break repair | Any process that modulates the frequency, rate or extent of double-strand break repair. |
DEK |
GO:2000780 | BP | negative regulation of double-strand break repair | Any process that stops, prevents or reduces the frequency, rate or extent of double-strand break repair. |
UBR5, TWIST1, RNF169, OTUB1 |
GO:2000781 | BP | positive regulation of double-strand break repair | Any process that activates or increases the frequency, rate or extent of double-strand break repair. |
FOXM1, SPIDR, SLF2, NUDT16, SLF1 |
GO:2000785 | BP | regulation of autophagosome assembly | Any process that modulates the frequency, rate or extent of autophagosome assembly. |
TBC1D12, RAB5A, RAB7A, NPRL3, RAB33A, RAB1B, TBC1D14, PIKFYVE |
GO:2000786 | BP | positive regulation of autophagosome assembly | Any process that activates or increases the frequency, rate or extent of autophagic vacuole assembly. |
RALB, PIP4K2B, RAB3GAP1, KIAA1324, RAB3GAP2, SH3GLB1 |
GO:2000791 | BP | negative regulation of mesenchymal cell proliferation involved in lung development | Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell proliferation involved in lung development. |
NFIB |
GO:2000793 | BP | cell proliferation involved in heart valve development | Any cell proliferation that is involved in heart valve development. |
TWIST1 |
GO:2000794 | BP | regulation of epithelial cell proliferation involved in lung morphogenesis | Any process that modulates the frequency, rate or extent of epithelial cell proliferation involved in lung morphogenesis. |
SOX9 |
GO:2000795 | BP | negative regulation of epithelial cell proliferation involved in lung morphogenesis | Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell proliferation involved in lung morphogenesis. |
NFIB |
GO:2000802 | BP | positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation | Any process that activates or increases the frequency, rate or extent of endocardial cushion to mesenchymal transition involved in heart valve formation. |
TWIST1 |
GO:2000806 | BP | positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled | Any process that activates or increases the frequency, rate or extent of termination of RNA polymerase II transcription, poly(A)-coupled. |
SETX |
GO:2000807 | BP | regulation of synaptic vesicle clustering | Any process that modulates the frequency, rate or extent of synaptic vesicle clustering. |
PCDH17 |
GO:2000808 | BP | negative regulation of synaptic vesicle clustering | Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle clustering. |
PTEN |
GO:2000809 | BP | positive regulation of synaptic vesicle clustering | Any process that activates or increases the frequency, rate or extent of synaptic vesicle clustering. |
CDH2, MAGI2, NLGN1 |
GO:2000810 | BP | regulation of bicellular tight junction assembly | Any process that modulates the frequency, rate or extent of tight junction assembly. |
MYO1C, SNAI2, GJA1, PRKACA, PKP2 |
GO:2000811 | BP | negative regulation of anoikis | Any process that stops, prevents or reduces the frequency, rate or extent of anoikis. |
SNAI2, ITGB1, ITGA5, BCL2, PIK3CA, NOTCH1, CAV1, TLE1, PTK2, MCL1, NTRK2, PDK4 |
GO:2000812 | BP | regulation of barbed-end actin filament capping | Any process that modulates the frequency, rate or extent of barbed-end actin filament capping. |
MTPN |
GO:2000813 | BP | negative regulation of barbed-end actin filament capping | Any process that stops, prevents or reduces the frequency, rate or extent of barbed-end actin filament capping. |
LRRC16A |
GO:2000818 | BP | negative regulation of myoblast proliferation | Any process that stops, prevents or reduces the frequency, rate or extent of myoblast proliferation. |
MSTN |
GO:2000819 | BP | regulation of nucleotide-excision repair | Any process that modulates the frequency, rate or extent of nucleotide-excision repair. |
CUL4A |
GO:2000820 | BP | negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation | Any negative regulation of transcription from RNA polymerase II promoter that is involved in smooth muscle cell differentiation. |
HEY1 |
GO:2000821 | BP | regulation of grooming behavior | Any process that modulates the frequency, rate or extent of grooming behavior. |
MC4R, DLG4, NRXN1 |
GO:2000824 | BP | negative regulation of androgen receptor activity | Any process that stops, prevents or reduces the frequency, rate or extent of androgen receptor activity. |
HEYL |
GO:2000825 | BP | positive regulation of androgen receptor activity | Any process that activates or increases the frequency, rate or extent of androgen receptor activity. |
BUD31 |
GO:2000827 | BP | mitochondrial RNA surveillance | The set of processes involved in identifying and degrading defective or aberrant RNAs that takes place in the mitochondrion. |
SUPV3L1 |
GO:2000828 | BP | regulation of parathyroid hormone secretion | Any process that modulates the frequency, rate or extent of parathyroid hormone secretion. |
GNAS, GNAS |
GO:2000830 | BP | positive regulation of parathyroid hormone secretion | Any process that activates or increases the frequency, rate or extent of parathyroid hormone secretion. |
FGFR1 |
GO:2000845 | BP | positive regulation of testosterone secretion | Any process that activates or increases the frequency, rate or extent of testosterone secretion. |
TMF1 |
GO:2000850 | BP | negative regulation of glucocorticoid secretion | Any process that stops, prevents or reduces the frequency, rate or extent of glucocorticoid secretion. |
CRY1 |
GO:2000852 | BP | regulation of corticosterone secretion | Any process that modulates the frequency, rate or extent of corticosterone secretion. |
POMC |
GO:2000860 | BP | positive regulation of aldosterone secretion | Any process that activates or increases the frequency, rate or extent of aldosterone secretion. |
BMP6, C1QTNF1 |
GO:2000864 | BP | regulation of estradiol secretion | Any process that modulates the frequency, rate or extent of estradiol secretion. |
KDM5B |
GO:2000870 | BP | regulation of progesterone secretion | Any process that modulates the frequency, rate or extent of progesterone secretion. |
GDF9 |
GO:2000872 | BP | positive regulation of progesterone secretion | Any process that activates or increases the frequency, rate or extent of progesterone secretion. |
RETN |
GO:2000969 | BP | positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity | Any process that activates or increases the frequency, rate or extent of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity. |
ARC |
GO:2000973 | BP | regulation of pro-B cell differentiation | Any process that modulates the frequency, rate or extent of pro-B cell differentiation. |
SOS1, FLCN, FNIP1 |
GO:2000974 | BP | negative regulation of pro-B cell differentiation | Any process that stops, prevents or reduces the frequency, rate or extent of pro-B cell differentiation. |
NOTCH1, HES1 |
GO:2000978 | BP | negative regulation of forebrain neuron differentiation | Any process that stops, prevents or reduces the frequency, rate or extent of forebrain neuron differentiation. |
HES1 |
GO:2000979 | BP | positive regulation of forebrain neuron differentiation | Any process that activates or increases the frequency, rate or extent of forebrain neuron differentiation. |
PROX1 |
GO:2000984 | BP | negative regulation of ATP citrate synthase activity | Any process that stops, prevents or reduces the frequency, rate or extent of ATP citrate synthase activity. |
CHCHD10, PHPT1 |
GO:2000987 | BP | positive regulation of behavioral fear response | Any process that activates or increases the frequency, rate or extent of behavioral fear response. |
PENK, GJA1, MEF2C |
GO:2001013 | BP | epithelial cell proliferation involved in renal tubule morphogenesis | Any epithelial cell proliferation that is involved in renal tubule morphogenesis. |
MTSS1, LGR5, MEF2C, LGR4 |
GO:2001014 | BP | regulation of skeletal muscle cell differentiation | Any process that modulates the frequency, rate or extent of skeletal muscle cell differentiation. |
DDX5, NR1D2, DDX17, UQCC2 |
GO:2001015 | BP | negative regulation of skeletal muscle cell differentiation | Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle cell differentiation. |
S100B, CAPN3 |
GO:2001016 | BP | positive regulation of skeletal muscle cell differentiation | Any process that activates or increases the frequency, rate or extent of skeletal muscle cell differentiation. |
ARNTL, GPC1, MEF2C |
GO:2001020 | BP | regulation of response to DNA damage stimulus | Any process that modulates the frequency, rate or extent of response to DNA damage stimulus. |
IER3, NEK4, CASP9, MCL1, NPAS2 |
GO:2001022 | BP | positive regulation of response to DNA damage stimulus | Any process that activates or increases the frequency, rate or extent of response to DNA damage stimulus. |
MYC, HMGA2, PRKCD, FMR1, NSMCE4A, BCLAF1 |
GO:2001023 | BP | regulation of response to drug | Any process that modulates the frequency, rate or extent of response to drug. |
ADIRF |
GO:2001027 | BP | negative regulation of endothelial cell chemotaxis | Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell chemotaxis. |
THBS1, NOTCH1 |
GO:2001028 | BP | positive regulation of endothelial cell chemotaxis | Any process that activates or increases the frequency, rate or extent of endothelial cell chemotaxis. |
HSPB1, MET, SEMA5A, PRKD1, PRKD2 |
GO:2001032 | BP | regulation of double-strand break repair via nonhomologous end joining | Any process that modulates the frequency, rate or extent of double-strand break repair via nonhomologous end joining. |
WHSC1, DEK |