| GO ID | Ontology | GO Term | Term Definition |
Proteins |
GO:2000054 | BP | negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification | Any process that stops, prevents, or reduces the frequency, rate or extent of Wnt signaling pathway involved in dorsal/ventral axis specification. |
SFRP1, SOST |
GO:2000055 | BP | positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification | Any process that activates or increases the frequency, rate or extent of Wnt signaling pathway involved in dorsal/ventral axis specification. |
LRP6 |
GO:2000057 | BP | negative regulation of Wnt signaling pathway involved in digestive tract morphogenesis | Any process that stops, prevents, or reduces the frequency, rate or extent of Wnt signaling pathway involved in digestive tract morphogenesis. |
SFRP5 |
GO:2000059 | BP | negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process | Any process that stops, prevents, or reduces the frequency, rate or extent of protein ubiquitination involved in ubiquitin-dependent protein catabolic process. |
PSEN1, HFE, PDCL3, TRIM39, SUFU |
GO:2000060 | BP | positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process | Any process that activates or increases the frequency, rate or extent of protein ubiquitination involved in ubiquitin-dependent protein catabolic process. |
AXIN1, CLU, PTEN, PTK2, FBXO22 |
GO:2000065 | BP | negative regulation of cortisol biosynthetic process | Any process that stops, prevents, or reduces the frequency, rate or extent of cortisol biosynthetic process. |
BMP2, DKK3 |
GO:2000074 | BP | regulation of type B pancreatic cell development | Any process that modulates the frequency, rate or extent of pancreatic B cell development. |
ARNTL, RHEB |
GO:2000077 | BP | negative regulation of type B pancreatic cell development | Any process that stops, prevents, or reduces the frequency, rate or extent of pancreatic B cell development. |
GSK3B |
GO:2000078 | BP | positive regulation of type B pancreatic cell development | Any process that activates or increases the frequency, rate or extent of pancreatic B cell development. |
BAD |
GO:2000080 | BP | negative regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation | Any process that stops, prevents, or reduces the frequency, rate or extent of canonical Wnt signaling pathway modulating the rate or frequency of pancreatic B cell proliferation. |
SFRP1 |
GO:2000095 | BP | regulation of Wnt signaling pathway, planar cell polarity pathway | Any process that modulates the frequency, rate or extent of Wnt signaling pathway, planar cell polarity pathway. |
NPHP3, MKS1, DACT1 |
GO:2000096 | BP | positive regulation of Wnt signaling pathway, planar cell polarity pathway | Any process that activates or increases the frequency, rate or extent of Wnt signaling pathway, planar cell polarity pathway. |
DAB2, RSPO3 |
GO:2000097 | BP | regulation of smooth muscle cell-matrix adhesion | Any process that modulates the frequency, rate or extent of smooth muscle cell-matrix adhesion. |
PLAU |
GO:2000098 | BP | negative regulation of smooth muscle cell-matrix adhesion | Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell-matrix adhesion. |
APOD, SERPINE1 |
GO:2000105 | BP | positive regulation of DNA-dependent DNA replication | Any process that activates or increases the frequency, rate or extent of DNA-dependent DNA replication. |
BMP4, BMP6 |
GO:2000107 | BP | negative regulation of leukocyte apoptotic process | Any process that stops, prevents, or reduces the frequency, rate or extent of leukocyte apoptotic process. |
HCLS1, CXCL12, MERTK |
GO:2000108 | BP | positive regulation of leukocyte apoptotic process | Any process that activates or increases the frequency, rate or extent of leukocyte apoptotic process. |
NR4A3 |
GO:2000109 | BP | regulation of macrophage apoptotic process | Any process that modulates the frequency, rate or extent of macrophage apoptotic process. |
TCP1 |
GO:2000110 | BP | negative regulation of macrophage apoptotic process | Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage apoptotic process. |
CCL5, VIMP |
GO:2000111 | BP | positive regulation of macrophage apoptotic process | Any process that activates or increases the frequency, rate or extent of macrophage apoptotic process. |
MEF2C |
GO:2000114 | BP | regulation of establishment of cell polarity | Any process that modulates the frequency, rate or extent of establishment of cell polarity. |
KRIT1, ROCK2, CDH5, RACK1, KANK1, RICTOR, RUFY3, KIF20B |
GO:2000116 | BP | regulation of cysteine-type endopeptidase activity | Any process that modulates the frequency, rate or extent of cysteine-type endopeptidase activity. |
PSMB9, BIRC3 |
GO:2000117 | BP | negative regulation of cysteine-type endopeptidase activity | Any process that stops, prevents, or reduces the frequency, rate or extent of cysteine-type endopeptidase activity. |
CST3, CST2, MT3, IFI16 |
GO:2000119 | BP | negative regulation of sodium-dependent phosphate transport | Any process that stops, prevents, or reduces the frequency, rate or extent of sodium-dependent phosphate transport. |
SFRP4 |
GO:2000121 | BP | regulation of removal of superoxide radicals | Any process that modulates the frequency, rate or extent of removal of superoxide radicals. |
DHFR, CD36 |
GO:2000124 | BP | regulation of endocannabinoid signaling pathway | Any process that modulates the frequency, rate or extent of endocannabinoid signaling pathway. |
MGLL, ABHD6 |
GO:2000134 | BP | negative regulation of G1/S transition of mitotic cell cycle | Any cell cycle regulatory process that prevents the commitment of a cell from G1 to S phase of the mitotic cell cycle. |
CTDSP2, CTDSPL, RB1, BCL2, CDKN1A, CDKN2B, SMARCA4, PTEN, PKD2, FHL1, EZH2, KANK2, JADE1, ZNF655, CTDSP1, BRD7, DACT1 |
GO:2000137 | BP | negative regulation of cell proliferation involved in heart morphogenesis | Any process that stops, prevents, or reduces the frequency, rate or extent of cell proliferation involved in heart morphogenesis. |
BMP4 |
GO:2000138 | BP | positive regulation of cell proliferation involved in heart morphogenesis | Any process that activates or increases the frequency, rate or extent of cell proliferation involved in heart morphogenesis. |
BMP10, SOX9 |
GO:2000142 | BP | regulation of DNA-templated transcription, initiation | Any process that modulates the frequency, rate or extent of DNA-templated transcription initiation. |
RRN3 |
GO:2000143 | BP | negative regulation of DNA-templated transcription, initiation | Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-templated transcription initiation. |
THRA |
GO:2000144 | BP | positive regulation of DNA-templated transcription, initiation | Any process that activates or increases the frequency, rate or extent of DNA-templated transcription initiation. |
MITF, JUN, FOSL1, CTNNB1, TWIST1, SETX, BCLAF1 |
GO:2000145 | BP | regulation of cell motility | Any process that modulates the frequency, rate or extent of cell motility. |
EREG, DAPK3, ROCK2, EGFR, RAF1, ERBB2, ERBB3, BTC, ABL2, CD81, RHOA, CDK6, NRG1, ERBB4, PKN1, PKN2, ARHGAP18, HBEGF, SSX2IP |
GO:2000146 | BP | negative regulation of cell motility | Any process that stops, prevents, or reduces the frequency, rate or extent of cell motility. |
SPINT2, FBLN1, CTNNA1, SPOCK3 |
GO:2000147 | BP | positive regulation of cell motility | Any process that activates or increases the frequency, rate or extent of cell motility. |
CSF1R, EPCAM, AKT2, TWIST1, SPOCK2, PHPT1 |
GO:2000156 | BP | regulation of retrograde vesicle-mediated transport, Golgi to ER | Any process that modulates the frequency, rate or extent of retrograde vesicle-mediated transport, Golgi to ER. |
BET1L |
GO:2000158 | BP | positive regulation of ubiquitin-specific protease activity | Any process that activates or increases the frequency, rate or extent of ubiquitin-specific protease (deubiquitinase) activity. |
VCP, TANK |
GO:2000167 | BP | regulation of planar cell polarity pathway involved in neural tube closure | Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in neural tube closure. |
NPHP3 |
GO:2000170 | BP | positive regulation of peptidyl-cysteine S-nitrosylation | Any process that activates or increases the frequency, rate or extent of peptidyl-cysteine S-nitrosylation. |
ACE |
GO:2000171 | BP | negative regulation of dendrite development | Any process that stops, prevents, or reduces the frequency, rate or extent of dendrite development. |
CARM1 |
GO:2000172 | BP | regulation of branching morphogenesis of a nerve | Any process that modulates the frequency, rate or extent of branching morphogenesis of a nerve. |
SHOX2, RTN4 |
GO:2000177 | BP | regulation of neural precursor cell proliferation | Any process that modulates the frequency, rate or extent of neural precursor cell proliferation. |
FOXO3, NF2, FOXO1, SHCBP1, PTBP2 |
GO:2000178 | BP | negative regulation of neural precursor cell proliferation | Any process that stops, prevents, or reduces the frequency, rate or extent of neural precursor cell proliferation. |
SPINT2, BTG2, ID2, ILK, RAPGEF1 |
GO:2000179 | BP | positive regulation of neural precursor cell proliferation | Any process that activates or increases the frequency, rate or extent of neural precursor cell proliferation. |
KDM1A, NES, ASCL1, GNG5, INSM1, KIAA1524, PROX1, DLL4, ADGRG1 |
GO:2000182 | BP | regulation of progesterone biosynthetic process | Any process that modulates the frequency, rate or extent of progesterone biosynthetic process. |
EGR1 |
GO:2000184 | BP | positive regulation of progesterone biosynthetic process | Any process that activates or increases the frequency, rate or extent of progesterone biosynthetic process. |
PPARGC1A |
GO:2000188 | BP | regulation of cholesterol homeostasis | Any process that modulates the frequency, rate or extent of cholesterol homeostasis. |
LDLR, NR1D1, RORA, NR1H2, SREBF2, NR1H3, NR1H4 |
GO:2000189 | BP | positive regulation of cholesterol homeostasis | Any process that activates or increases the frequency, rate or extent of cholesterol homeostasis. |
NPC1, NR1H3 |
GO:2000191 | BP | regulation of fatty acid transport | Any process that modulates the frequency, rate or extent of fatty acid transport. |
NCOR1, REPIN1 |
GO:2000194 | BP | regulation of female gonad development | Any process that modulates the frequency, rate or extent of female gonad development. |
NUPR1, INSR |
GO:2000195 | BP | negative regulation of female gonad development | Any process that stops, prevents, or reduces the frequency, rate or extent of female gonad development. |
WT1, ZFPM2 |
GO:2000210 | BP | positive regulation of anoikis | Any process that activates or increases the frequency, rate or extent of anoikis. |
SIK1, AES, MYBBP1A |
GO:2000213 | BP | positive regulation of glutamate metabolic process | Any process that activates or increases the frequency, rate or extent of glutamate metabolic process. |
NR1H4 |
GO:2000224 | BP | regulation of testosterone biosynthetic process | Any process that modulates the frequency, rate or extent of testosterone biosynthetic process. |
AKR1C3 |
GO:2000227 | BP | negative regulation of pancreatic A cell differentiation | Any process that stops, prevents, or reduces the frequency, rate or extent of pancreatic A cell differentiation. |
HES1 |
GO:2000230 | BP | negative regulation of pancreatic stellate cell proliferation | Any process that stops, prevents, or reduces the frequency, rate or extent of pancreatic stellate cell proliferation. |
PPARG |
GO:2000233 | BP | negative regulation of rRNA processing | Any process that stops, prevents, or reduces the frequency, rate or extent of rRNA processing. |
SHQ1, NUDT16 |
GO:2000249 | BP | regulation of actin cytoskeleton reorganization | Any process that modulates the frequency, rate or extent of actin cytoskeleton reorganization. |
RHOD, SEMA3E, DAPK3, TGFB1, CSF1R, PDGFRA, ABL2, ARHGDIA, ARHGDIB, PHPT1, F11R |
GO:2000251 | BP | positive regulation of actin cytoskeleton reorganization | Any process that activates or increases the frequency, rate or extent of actin cytoskeleton reorganization. |
HAX1, HCLS1, CDK5, TEK, BAIAP2L1 |
GO:2000252 | BP | negative regulation of feeding behavior | Any process that stops, prevents or reduces the frequency, rate or extent of feeding behavior. |
INS, TRH, MC4R, NPY2R, RETN |
GO:2000253 | BP | positive regulation of feeding behavior | Any process that activates or increases the frequency, rate or extent of feeding behavior. |
AGRP, NR4A3 |
GO:2000255 | BP | negative regulation of male germ cell proliferation | Any process that stops, prevents or reduces the frequency, rate or extent of male germ cell proliferation. |
PTGDS, PRDX4 |
GO:2000256 | BP | positive regulation of male germ cell proliferation | Any process that activates or increases the frequency, rate or extent of male germ cell proliferation. |
CIB1 |
GO:2000266 | BP | regulation of blood coagulation, intrinsic pathway | Any process that modulates the frequency, rate or extent of blood coagulation, intrinsic pathway. |
SERPINC1 |
GO:2000269 | BP | regulation of fibroblast apoptotic process | Any process that modulates the frequency, rate or extent of fibroblast apoptotic process. |
IER3IP1 |
GO:2000270 | BP | negative regulation of fibroblast apoptotic process | Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast apoptotic process. |
PIK3CA, PIK3CG, GAS6, SFRP1, CHD8, CFDP1 |
GO:2000271 | BP | positive regulation of fibroblast apoptotic process | Any process that activates or increases the frequency, rate or extent of fibroblast apoptotic process. |
BCL2L11, STK17B, BTG1, SFRP1 |
GO:2000272 | BP | negative regulation of receptor activity | Any process that stops, prevents or reduces the frequency, rate or extent of receptor activity. |
HFE, LYPD1, PCSK9, PPARGC1A |
GO:2000273 | BP | positive regulation of receptor activity | Any process that activates or increases the frequency, rate or extent of receptor activity. |
GREM1, IGF2, ANXA2, ACTN2, CDK5, NCOA2, HFE, PPARGC1B, SRA1, BAZ1B, MED16 |
GO:2000276 | BP | negative regulation of oxidative phosphorylation uncoupler activity | Any process that stops, prevents or reduces the frequency, rate or extent of oxidative phosphorylation uncoupler activity. |
PPIF, TWIST1 |
GO:2000278 | BP | regulation of DNA biosynthetic process | Any process that modulates the frequency, rate or extent of DNA biosynthetic process. |
CDKN1A, SH2B1 |
GO:2000279 | BP | negative regulation of DNA biosynthetic process | Any process that stops, prevents or reduces the frequency, rate or extent of DNA biosynthetic process. |
GJA1, DUSP1, BMPR2, ANKRD1, RGN, ADIPOQ, DACH1 |
GO:2000286 | BP | receptor internalization involved in canonical Wnt signaling pathway | A receptor internalization process that contributes to canonical Wnt signaling pathway. |
RAB5A, CAV1 |
GO:2000288 | BP | positive regulation of myoblast proliferation | Any process that activates or increases the frequency, rate or extent of myoblast proliferation. |
SOX15, PPARD, PITX2, PAXBP1 |
GO:2000296 | BP | negative regulation of hydrogen peroxide catabolic process | Any process that stops, prevents or reduces the frequency, rate or extent of hydrogen peroxide catabolic process. |
HP, MT3 |
GO:2000297 | BP | negative regulation of synapse maturation | Any process that stops, prevents or reduces the frequency, rate or extent of synapse maturation. |
NFATC4 |
GO:2000299 | BP | negative regulation of Rho-dependent protein serine/threonine kinase activity | Any process that stops, prevents or reduces the frequency, rate or extent of Rho-dependent protein serine/threonine kinase activity. |
CHORDC1 |
GO:2000300 | BP | regulation of synaptic vesicle exocytosis | Any process that modulates the frequency, rate or extent of synaptic vesicle exocytosis. |
SYN1, RAB5A, RIMS4, RIMS2 |
GO:2000301 | BP | negative regulation of synaptic vesicle exocytosis | Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle exocytosis. |
RAP1A, FMR1 |
GO:2000302 | BP | positive regulation of synaptic vesicle exocytosis | Any process that activates or increases the frequency, rate or extent of synaptic vesicle exocytosis. |
NLGN1 |
GO:2000304 | BP | positive regulation of ceramide biosynthetic process | Any process that activates or increases the frequency, rate or extent of ceramide biosynthetic process. |
CYR61, TNF, RACK1, PRKCD, NSMAF |
GO:2000309 | BP | positive regulation of tumor necrosis factor (ligand) superfamily member 11 production | Any process that activates or increases the frequency, rate or extent of tumor necrosis factor (ligand) superfamily member 11 production. |
ADAM8 |
GO:2000310 | BP | regulation of N-methyl-D-aspartate selective glutamate receptor activity | Any process that modulates the frequency, rate or extent of N-methyl-D-aspartate selective glutamate receptor activity. |
DAPK1, DLG4, MEF2C, MAPK8IP2, NLGN1, PPARGC1A |
GO:2000311 | BP | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity | Any process that modulates the frequency, rate or extent of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity. |
MEF2C, MAPK8IP2, NLGN1, MINK1, CACNG8 |
GO:2000312 | BP | regulation of kainate selective glutamate receptor activity | Any process that modulates the frequency, rate or extent of kainate selective glutamate receptor activity. |
KLHL24, NETO2 |
GO:2000318 | BP | positive regulation of T-helper 17 type immune response | Any process that activates or increases the frequency, rate or extent of T-helper 17 type immune response. |
IL12RB1, PRKCQ |
GO:2000320 | BP | negative regulation of T-helper 17 cell differentiation | Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 17 cell differentiation. |
FOXP3 |
GO:2000323 | BP | negative regulation of glucocorticoid receptor signaling pathway | Any process that stops, prevents or reduces the frequency, rate or extent of glucocorticoid receptor signaling pathway. |
ARNTL, PER1, PHB, CRY1 |
GO:2000327 | BP | positive regulation of ligand-dependent nuclear receptor transcription coactivator activity | Any process that activates or increases the frequency, rate or extent of ligand-dependent nuclear receptor transcription coactivator activity. |
CNOT6 |
GO:2000330 | BP | positive regulation of T-helper 17 cell lineage commitment | Any process that activates or increases the frequency, rate or extent of T-helper 17 cell lineage commitment. |
IL12RB1 |
GO:2000334 | BP | positive regulation of blood microparticle formation | Any process that activates or increases the frequency, rate or extent of blood microparticle formation. |
TNF, CD36 |
GO:2000340 | BP | positive regulation of chemokine (C-X-C motif) ligand 1 production | Any process that activates or increases the frequency, rate or extent of chemokine (C-X-C motif) ligand 1 production. |
TIRAP, TRPV4 |
GO:2000342 | BP | negative regulation of chemokine (C-X-C motif) ligand 2 production | Any process that stops, prevents or reduces the frequency, rate or extent of chemokine (C-X-C motif) ligand 2 production. |
KLF4, MAP2K5 |
GO:2000343 | BP | positive regulation of chemokine (C-X-C motif) ligand 2 production | Any process that activates or increases the frequency, rate or extent of chemokine (C-X-C motif) ligand 2 production. |
TNF, CD74, MIF, TIRAP, HDAC1 |
GO:2000344 | BP | positive regulation of acrosome reaction | Any process that activates or increases the frequency, rate or extent of the acrosome reaction. |
ZP3, PLCB1 |
GO:2000345 | BP | regulation of hepatocyte proliferation | Any process that modulates the frequency, rate or extent of hepatocyte proliferation. |
SULF2 |
GO:2000346 | BP | negative regulation of hepatocyte proliferation | Any process that stops, prevents or reduces the frequency, rate or extent of hepatocyte proliferation. |
CPB2 |
GO:2000347 | BP | positive regulation of hepatocyte proliferation | Any process that activates or increases the frequency, rate or extent of hepatocyte proliferation. |
XBP1, TNFAIP3 |
GO:2000348 | BP | regulation of CD40 signaling pathway | Any process that modulates the frequency, rate or extent of signaling via the CD40 signaling pathway. |
FANCD2 |
GO:2000349 | BP | negative regulation of CD40 signaling pathway | Any process that stops, prevents or reduces the frequency, rate or extent of signaling via the CD40 signaling pathway. |
TNFAIP3 |